All Publications since 2000
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Aubele, M. ; Ludyga, N. ; Braselmann, H. ; Atkinson, M.J. ; Auer, G. ; Anastasov, N.
Targeted modulation of HER receptor signaling in breast cancer using miR-21 .Schmidl, S.
The role of AID and NF-κB for B cell development and lymphomagenesis.Luber, B. ; Deplazes, J. ; Keller, G. ; Walch, A.K. ; Rauser, S. ; Eichmann, M. ; Langer, R. ; Höfler, H. ; Hegewisch-Becker, S. ; Folprecht, G. ; Wöll, E. ; Decker, T.-M. ; Endlicher, E. ; Lorenzen, S. ; Fend, F. ; Peschel, C. ; Lordick, F.
Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: Results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).Baumhoer, D. ; Elsner, M. ; Smida, J. ; Zillmer, S. ; Rauser, S. ; Schoene, C. ; Balluff, B. ; Bielack, S. ; Jundt, G. ; Walch, A.K. ; Nathrath, M.
CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients.Marjanovic, G. ; Schricker, M. ; Walch, A.K. ; zur Hausen, A. ; Hopt, U.T. ; Imdahl, A. ; Makowiec, F.
Detection of lymph node involvement by cytokeratin immunohistochemistry is an independent prognostic factor after curative resection of esophageal cancer.Pallua, J.D. ; Schaefer, G. ; Bittner, L.K. ; Pezzei, C. ; Huck-Pezzei, V. ; Schoenbichler, S.A. ; Meding, S. ; Rauser, S. ; Walch, A.K. ; Handler, M. ; Netzer, M. ; Osl, M. ; Seger, M. ; Pfeifer, B. ; Baumgartner, C. ; Lindner, H. ; Kremser, L. ; Sarg, B. ; Klocker, H. ; Bartsch, G. ; Bonn, G.K. ; Huck, C.W.
Matrix-assisted laser desorption-ionization imaging mass spectrometry for direct tissue analysis.Walch, A.K. ; Rauser, S. ; Höfler, H.
MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissues.Mutze, K. ; Langer, R. ; Schumacher, F. ; Becker, K. ; Ott, K. ; Novotny, A. ; Hapfelmeier, A. ; Höfler, H. ; Keller, G.
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.Lee, M.S.
The MENX syndrome: An animal model to study the role of p27 in tumor predisposition and the response of neuroendocrine tumors to therapeutic agents.Ewald, P.S.
Untersuchungen zur intratumoralen Heterogenität der Genexpression beim Adenokarzinom des Ösophagus.Thomas, D.M. ; Wilhelm, M. ; Cleton-Jansen, A.M. ; Dirksen, U. ; Entz-Werlé, N. ; Gelderblom, H. ; Hassan, B. ; Jürgens, H. ; Koster, J. ; Kovar, H. ; Lankester, A.C. ; Lewis, I.J. ; Myklebost, O. ; Nathrath, M. ; Picci, P. ; Whelan, J.S. ; Hogendoorn, P.C.W. ; Bielack, S.S.
Workshop report on the European Bone Sarcoma Networking Meeting: Integration of clinical trials with tumor biology.Schumann, R.G. ; Eibl, K.H. ; Zhao, F. ; Scheerbaum, M. ; Scheler, R. ; Schaumberger, M.M. ; Wehnes, H. ; Walch, A.K. ; Haritoglou, C. ; Kampik, A. ; Gandorfer, A.
Immunocytochemical and ultrastructural evidence of glial cells and hyalocytes in internal limiting membrane specimens of idiopathic macular holes.Loos, M. ; Langer, R. ; Schuster, T. ; Gertler, R. ; Walch, A.K. ; Rauser, S. ; Friess, H. ; Feith, M.
Clinical significance of the costimulatory molecule B7-H1 in Barrett carcinoma.Zischka, H. ; Lichtmannegger, J. ; Schmitt, S. ; Jägemann, N. ; Schulz, S. ; Wartini, D. ; Jennen, L. ; Rust, C. ; Larochette, N. ; Galluzzi, L. ; Chajes, V. ; Bandow, N. ; Gilles, V.S. ; DiSpirito, A.A. ; Esposito, I. ; Göttlicher, M. ; Summer, K.H. ; Kroemer, G.
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.Braren, R. ; Altomonte, J. ; Settles, M. ; Neff, F. ; Esposito, I. ; Ebert, O. ; Schwaiger, M. ; Rummeny, E. ; Steingoetter, A.
Validation of preclinical multiparametric imaging for prediction of necrosis in hepatocellular carcinoma after embolization.Balluff, B. ; Schöne, C. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry for direct tissue analysis: Technological advancements and recent applications.Alexandrov, T. ; Meding, S. ; Trede, D. ; Kobarg, J.H. ; Balluff, B. ; Walch, A.K. ; Thiele, H. ; Maass, P.
Super-resolution segmentation of imaging mass spectrometry data: Solving the issue of low lateral resolution.Lian, F. ; Xing, X. ; Yuan, G. ; Schäfer, C. ; Rauser, S. ; Walch, A.K. ; Röcken, C. ; Ebeling, M. ; Wright, M.B. ; Schmid, R.M. ; Ebert, M.P. ; Burgermeister, E.
Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage.Wu, Z. ; Doondeea, J.B. ; Moghaddas Gholami, A. ; Janning, M.C. ; Lemeer, S. ; Kramer, K. ; Eccles, S.A. ; Gollin, S.M. ; Grenman, R. ; Walch, A.K. ; Feller, S.M. ; Kuster, B.
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.Bertossi, A. ; Aichinger, M. ; Sansonetti, P. ; Lech, M. ; Neff, F. ; Pal, M. ; Wunderlich, F.T. ; Anders, H.J. ; Klein, L. ; Schmidt-Supprian, M.
Loss of Roquin induces early death and immune deregulation but not autoimmunity.Waser, B. ; Beetschen, K. ; Pellegata, N.S. ; Reubi, J.C.
Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: Relevance for incretin-based diabetes therapy.Miederer, M. ; Molatore, S. ; Marinoni, I. ; Perren, A. ; Spitzweg, C. ; Reder, S. ; Wester, H.J. ; Buck, A.K. ; Schwaiger, M. ; Pellegata, N.S.
Functional imaging of pheochromocytoma with 68Ga-DOTATOC and 68C-HED in a genetically defined rat model of multiple endocrine neoplasia.Lee, M.S. ; Theodoropoulou, M. ; Graw, J. ; Roncaroli, F. ; Zatelli, M.C. ; Pellegata, N.S.
Levels of p27 sensitize to dual PI3K/mTOR inhibition.Balluff, B. ; Rauser, S. ; Meding, S. ; Elsner, M. ; Schöne, C. ; Feuchtinger, A. ; Schuhmacher, C. ; Novotny, A. ; Jütting, U. ; Maccarrone, G. ; Sarioglu, H. ; Ueffing, M. ; Braselmann, H. ; Zitzelsberger, H. ; Schmid, R.M. ; Höfler, H. ; Ebert, M.P. ; Walch, A.K.
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer.Wirth, E.K. ; Sheu, S.Y. ; Chiu-Ugalde, J. ; Sapin, R. ; Klein, M.O. ; Mossbrugger, I. ; Quintanilla-Martinez, L. ; Hrabě de Angelis, M. ; Krude, H. ; Riebel, T. ; Rothe, K. ; Köhrle, J. ; Schmid, K.W. ; Schweizer, U. ; Grüters, A.
Monocarboxylate transporter 8 deficiency: Altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.Langer, R. ; Rauser, S. ; Feith, M. ; Nährig, J.M. ; Feuchtinger, A. ; Friess, H. ; Höfler, H. ; Walch, A.K.
Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.Schlegel, J. ; Schäfer, A. ; Zimmer, C.
Hirntumorstammzellen und Therapieresistenz in malignen Gliomen.Deininger, S.O. ; Cornett, D.S. ; Paape, R. ; Becker, M. ; Pineau, C. ; Rauser, S. ; Walch, A.K. ; Wolski, E.
Normalization in MALDI-TOF imaging datasets of proteins: Practical considerations.Timme, S. ; Schmitt, E. ; Stein, S. ; Schwarz-Finsterle, J. ; Wagner, J. ; Walch, A.K. ; Werner, M. ; Hausmann, M. ; Wiech, T.
Nuclear position and shape deformation of chromosome 8 territories in pancreatic ductal adenocarcinoma.Ebert, G. ; Poeck, H. ; Lucifora, J. ; Baschuk, N. ; Esser, K. ; Esposito, I. ; Hartmann, G. ; Protzer, U.
5' triphosphorylated small interfering RNAs control replication of hepatitis B virus and induce an interferon response in human liver cells and mice.Paron, I. ; Berchtold, S. ; Vörös, J. ; Shamarla, M. ; Erkan, M. ; Höfler, H. ; Esposito, I.
Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway.Straub, B.K. ; Esposito, I. ; Gotthardt, D. ; Radeleff, B. ; Antolovic, D. ; Flechtenmacher, C. ; Schirmacher, P.
IgG4-associated cholangitis with cholangiocarcinoma.Raab, M. ; Kappel, S. ; Krämer, A. ; Sanhaji, M. ; Matthess, Y. ; Kurunci-Csacsko, E. ; Calzada-Wack, J. ; Rathkolb, B. ; Rozman, J. ; Adler, T. ; Busch, D.H. ; Esposito, I. ; Fuchs, H. ; Gailus-Durner, V. ; Klingenspor, M. ; Wolf, E. ; Sänger, N. ; Prinz, F. ; Hrabě de Angelis, M. ; Seibler, J. ; Yuan, J. ; Bergmann, M. ; Knecht, R. ; Kreft, B. ; Strebhardt, K.
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.Becker, K. ; Langer, R. ; Reim, D. ; Novotny, A. ; Meyer zum Büschenfelde, C. ; Engel, J. ; Friess, H. ; Höfler, H.
Significance of histopathological tumor regression after neoadjuvant chemotherapy in gastric adenocarcinomas: A summary of 480 cases.Berg, D. ; Langer, R. ; Tran, K. ; Walch, A.K. ; Schuster, T. ; Bronger, H. ; Becker, K.F.
Protein microarray-based comparison of HER2, estrogen receptor, and progesterone receptor status in core biopsies and surgical specimens from FFPE breast cancer tissues.Vela-Chávez, T. ; Adam, P. ; Kremer, M. ; Bink, K. ; Bacon, C.M. ; Menon, G. ; Ferry, J.A. ; Fend, F. ; Jaffe, E.S. ; Quintanilla-Martinez, L.
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus.Langer, R. ; Becker, K. ; Feith, M. ; Friess, H. ; Höfler, H. ; Keller, G.
Genetic aberrations in primary esophageal melanomas: Molecular analysis of c-KIT, PDGFR, KRAS, NRAS and BRAF in a series of 10 cases.Schlitter, A.M. ; Esposito, I. ; Klöppel, G.
Klassifikation und Diagnose zystischer Pancreastumoren.Eberhardt, C. ; Amann, B. ; Feuchtinger, A. ; Hauck, S.M. ; Deeg, C.A.
Differential expression of inwardly rectifying K+ channels and aquaporins 4 and 5 in autoimmune uveitis indicates misbalance in Müller glial cell-dependent ion and water homeostasis.Azimzadeh, O. ; Scherthan, H. ; Sarioglu, H. ; Barjaktarovic, Z. ; Conrad, M. ; Vogt, A. ; Calzada-Wack, J. ; Neff, F. ; Aubele, M. ; Buske, C. ; Atkinson, M.J. ; Tapio, S.
Rapid proteomic remodeling of cardiac tissue caused by total body ionizing radiation.Ludyga, N. ; Anastasov, N. ; Gonzalez-Vasconcellos, I. ; Ram, M. ; Höfler, H. ; Aubele, M.
Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer.Baumhoer, D. ; Smida, J. ; Specht, K. ; Bink, K. ; Quintanilla-Martinez, L. ; Rosemann, M. ; Siggelkow, H. ; Nathrath, W.B. ; Atkinson, M.J. ; Bielack, S. ; Jundt, G. ; Nathrath, M.
Aberrant expression of the human epidermal growth factor receptor 2 oncogene is not a common feature in osteosarcoma.Abe, K. ; Fuchs, H. ; Boersma, A. ; Hans, W. ; Yu, P. ; Kalaydjiev, S. ; Klaften, M. ; Adler, T. ; Calzada-Wack, J. ; Mossbrugger, I. ; Rathkolb, B. ; Rozman, J. ; Prehn, C. ; Maraslioglu, M. ; Kametani, Y. ; Shimada, S. ; Adamski, J. ; Busch, D.H. ; Esposito, I. ; Klingenspor, M. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Katan, M. ; Marschall, S. ; Soewarto, D. ; Wagner, S. ; Hrabě de Angelis, M.
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.Bader, S.R. ; Fischer, A. ; Emrich, D. ; Jütting, U. ; Weyh, T. ; Kaspers, B. ; Matiasek, K.
Evaluation of lumbosacral nerve root conduction in chickens by electrophysiological testing including high-resolution spinal magnetic stimulation.Horsch, M. ; Seeburg, PH. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Calzada-Wack, J. ; Garrett, L. ; Götz, A. ; Hans, W. ; Higuchi, M. ; Hölter, S.M. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Adamski, J. ; Busch, D.H. ; Esposito, I. ; Graw, J. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Mempel, M. ; Ollert, M. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Beckers, J.
Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice.Sibbing, D. ; Pfeufer, A. ; Perisic, T. ; Mannes, A.M. ; Fritz-Wolf, K. ; Unwin, S. ; Sinner, M.F. ; Gieger, C. ; Gloeckner, C.J. ; Wichmann, H.-E. ; Kremmer, E. ; Schäfer, Z. ; Walch, A.K. ; Hinterseer, M. ; Näbauer, M. ; Kääb, S. ; Kastrati, A. ; Schömig, A. ; Meitinger, T. ; Bornkamm, G.W. ; Conrad, M. ; von Beckerath, N.
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy.Costa-Guda, J. ; Marinoni, I. ; Molatore, S. ; Pellegata, N.S. ; Arnold, A.
Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomas.Saarikangas, J. ; Mattila, PK. ; Varjosalo, M. ; Bovellan, M. ; Hakanen, J. ; Calzada-Wack, J. ; Tost, M. ; Jennen, L. ; Rathkolb, B. ; Hans, W. ; Horsch, M. ; Hyvönen, M.E. ; Perälä, N. ; Fuchs, H. ; Gailus-Durner, V. ; Esposito, I. ; Wolf, E. ; Hrabě de Angelis, M. ; Frilander, MJ. ; Savilahti, H. ; Sariola, H. ; Sainio, K. ; Lehtonen, S. ; Taipale, J. ; Salminen, M. ; Lappalainen, P.
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.Lagarrigue, M. ; Becker, M. ; Lavigne, R. ; Deininger, S.O. ; Walch, A.K. ; Aubry, F. ; Suckau, D. ; Pineau, C.
Revisiting rat spermatogenesis with MALDI imaging at 20- μm resolution.Fuchs, H. ; Gailus-Durner, V. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Neff, F. ; Götz, A.A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Kastenmüller, G. ; Kemter, E. ; Lengger, C. ; Maier, H. ; Matloka, M. ; Möller, G. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Römisch-Margl, W. ; Rozman, J. ; Wang-Sattler, R. ; Schrewe, A. ; Stoeger, C. ; Tost, M. ; Adamski, J. ; Aigner, B. ; Beckers, J. ; Behrendt, H. ; Busch, D.H. ; Esposito, I. ; Graw, J. ; Illig, T. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Mempel, M. ; Neschen, S. ; Ollert, M. ; Schulz, S. ; Suhre, K. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M.
Mouse phenotyping.González-Vasconcellos, I.M. ; Domke, T.A.J. ; Kuosaite, V. ; Esposito, I. ; Sanli-Bonazzi, B. ; Nathrath, M. ; Atkinson, M.J. ; Rosemann, M.
Differential effects of genes of the Rb1 signalling pathway on osteosarcoma incidence and latency in alpha-particle irradiated mice.Wolff, C. ; Malinowsky, K. ; Berg, D. ; Schragner, K. ; Schuster, T: ; Walch, A.K. ; Bronger, H. ; Höfler, H. ; Becker, K.F.
Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: New insights from protein microarray analysis.Marinoni, I. ; Pellegata, N.S.
p27kip1: A new multiple endocrine neoplasia gene?Stangl, S. ; Gehrmann, M. ; Dressel, R. ; Alves, F. ; Dullin, C. ; Themelis, G. ; Ntziachristos, V. ; Staeblein, E. ; Walch, A.K. ; Winkelmann, I. ; Multhoff, G.
In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody.