All Publications since 2000
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Mengel, D. ; Röskam, S. ; Neff, F. ; Balakrishnan, K. ; Deuster, O. ; Gold, M. ; Oertel, W.H. ; Bacher, M. ; Bach, J.P. ; Dodel, R.
Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment.Aichler, M.
Bildgebende MS in biomedizinischer Forschung und Diagnostik.Sluka, S.H.M. ; Akhmedov, A. ; Klein-Rodewald, T. ; Horsch, M. ; Rathkolb, B. ; Neff, F. ; Hrabě de Angelis, M. ; Ruf, W. ; Luescher, T.F. ; Tanner, F.C.
Single housing reduces lung hemorrhages in male mice with tissue factor disulfide mutation and protects them from lethality.Frankó, A. ; Baris, O.R. ; Bergschneider, E. ; von Toerne, C. ; Hauck, S.M. ; Aichler, M. ; Walch, A.K. ; Wurst, W. ; Wiesner, R.J. ; Johnston, I.C.D. ; Hrabě de Angelis, M.
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.Serpi, R. ; Klein-Rodewald, T. ; Calzada-Wack, J. ; Neff, F. ; Schuster, T. ; Gailus-Durner, V. ; Fuchs, H. ; Poutanen, M. ; Hrabě de Angelis, M. ; Esposito, I.
Inbred wild type mouse strains have distinct spontaneous morphological phenotypes.Ale, A.B.F ; Siebenhaar, F. ; Kosanke, K. ; Aichler, M. ; Radrich, K. ; Heydrich, S. ; Schiemann, M. ; Bielicki, I. ; Noel, P.B. ; Braren, R. ; Maurer, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Wildgruber, M.
Cardioprotective C-kit+ bone marrow cells attenuate apoptosis after acute myocardial infarction in mice – in-vivo assessment with fluorescence molecular imaging.Mittermeyer, G. ; Malinowsky, K. ; Beese, C. ; Höfler, H. ; Schmalfeldt, B. ; Becker, K.F. ; Avril, S.
Variation in cell signaling protein expression may introduce sampling bias in primary epithelial ovarian cancer.Gaertner, F.C. ; Wiedemann, T. ; Yousefi, B.H. ; Lee, M.S. ; Repokis, I. ; Higuchi, T. ; Nekolla, S.G. ; Yu, M. ; Robinson, S. ; Schwaiger, M. ; Pellegata, N.S.
Preclinical evaluation of 18F-LMI1195 for in vivo imaging of pheochromocytoma in the MENX tumor model.Lee, M. ; Pellegata, N.S.
Multiple endocrine neoplasia syndromes associated with mutation of p27.Falkenberg, N. ; Anastasov, N. ; Rappl, K. ; Braselmann, H. ; Auer, G. ; Walch, A.K. ; Huber, M. ; Höfig, I. ; Schmitt, M. ; Höfler, H. ; Atkinson, M.J. ; Aubele, M.
MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion.Gross, E. ; Meul, C. ; Raab, S. ; Propping, C. ; Avril, S. ; Aubele, M. ; Gkazepis, A. ; Schuster, T. ; Grebenchtchikov, N. ; Schmitt, M. ; Kiechle, M. ; Meijer, J. ; Vijzelaar, R. ; Meindl, A. ; van Kuilenburg, A.B.
Somatic copy number changes in DPYD are associated with lower risk of recurrence in triple-negative breast cancers.Altomonte, J. ; Marozin, S. ; de Toni, E.N. ; Rizzani, A. ; Esposito, I. ; Steiger, K. ; Feuchtinger, A. ; Hellerbrand, C. ; Schmid, R.M. ; Ebert, O.
Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.Grunewald, T.G. ; Willier, S. ; Janik, D. ; Unland, R. ; Reiss, C. ; da Costa, O.P. ; Buch, T. ; Dirksen, U. ; Richter, G.H. ; Neff, F. ; Burdach, S. ; Butt, E.
The zyxin-related protein Thyroid Receptor Interacting Protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth.Poos, K. ; Smida, J. ; Nathrath, M. ; Maugg, D. ; Baumhoer, D. ; Korsching, E.
How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation.Hahne, H. ; Pachl, F. ; Ruprecht, B. ; Maier, S.K. ; Klaeger, S. ; Helm, D. ; Médard, G. ; Wilm, M. ; Lemeer, S. ; Kuster, B.
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.Schmitt, S. ; Saathoff, F. ; Meissner, L. ; Schropp, E.-M. ; Lichtmannegger, J. ; Schulz, S. ; Eberhagen, C. ; Borchard, S. ; Aichler, M. ; Adamski, J. ; Plesnila, N. ; Rothenfusser, S. ; Kroemer, G. ; Zischka, H.
A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.Pallua, J.D. ; Schaefer, G. ; Seifarth, C. ; Becker, M. ; Meding, S. ; Rauser, S. ; Walch, A.K. ; Handler, M. ; Netzer, M. ; Popovscaia, M. ; Osl, M. ; Baumgartner, C. ; Lindner, H. ; Kremser, L. ; Sarg, B. ; Bartsch, G. ; Huck, C.W. ; Bonn, G.K. ; Klocker, H.
MALDI-MS tissue imaging identification of biliverdin reductase B overexpression in prostate cancer.Simon, M.M. ; Greenaway, S. ; White, J.K. ; Fuchs, H. ; Gailus-Durner, V. ; Sorg, T. ; Wong, K. ; Bedu, E. ; Cartwright, E.J. ; Dacquin, R. ; Estabel, J. ; Graw, J. ; Ingham, N.J. ; Jackson, I.J. ; Lengeling, A. ; Mandillo, S. ; Marvel, J. ; Meziane, H. ; Preitner, F. ; Puk, O. ; Roux, M. ; Adams, D.J. ; Atkins, S. ; Ayadi, A. ; Becker, L. ; Blake, A. ; Brooker, D. ; Cater, H. ; Champy, M.-F. ; Combe, R. ; Danecek, P. ; di Fenza, A. ; Gates, H. ; Gerdin, A.-K. ; Golini, E. ; Hancock, J.M. ; Hans, W. ; Hölter, S.M. ; Hough, T. ; Jurdic, P. ; Keane, T.M ; Morgan, H. ; Müller, W. ; Neff, F. ; Nicholson, G. ; Pasche, B. ; Roberson, L.-A. ; Rozman, J. ; Sanderson, M. ; Santos, L. ; Selloum, M. ; Shannon, C. ; Southwell, A. ; Tocchini-Valentini, G.P. ; Vancollie, V.E. ; Wells, S. ; Westerberg, H. ; Wurst, W. ; Zi, M. ; Yalcin, B. ; Ramirez-Solis, R. ; Steel, K.P. ; Mallon, A.-M. ; Hrabě de Angelis, M. ; Herault, Y. ; Brown, S.D.M.
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Balluff, B.
MALDI imaging mass spectrometry in clinical proteomics research of gastric cancer tissues.Neubert, P. ; Walch, A.K.
Current frontiers in clinical research application of MALDI imaging mass spectrometry.Slotta-Huspenina, J. ; Wolff, C. ; Drecoll, E. ; Feith, M. ; Bettstetter, M. ; Malinowsky, K. ; Bauer, L. ; Becker, K. ; Ott, K. ; Höfler, H. ; Becker, K.F. ; Langer, R.
A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas.Berezowska, S. ; Novotny, A. ; Bauer, K. ; Feuchtinger, A. ; Slotta-Huspenina, J. ; Becker, K. ; Langer, R. ; Walch, A.K.
Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.Sun, N. ; Walch, A.K.
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels.Neff, F. ; Flores-Dominguez, D. ; Ryan, D.P. ; Horsch, M. ; Schröder, S. ; Adler, T. ; Afonso, L.C. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hans, W. ; Hettich, M.M. ; Holtmeier, R. ; Hölter, S.M. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Naton, B. ; Ordemann, R. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Ehninger, G. ; Graw, J. ; Höfler, H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Stypmann, J. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Ehniger, D.
Rapamycin extends murine lifespan but has limited effects on aging.Sabrautzki, S. ; Janas, E. ; Lorenz-Depiereux, B. ; Calzada-Wack, J. ; Aguilar-Pimentel, J.A. ; Rathkolb, B. ; Adler, T. ; Cohrs, C.M. ; Hans, W. ; Diener, S. ; Fuchs, H. ; Gailus-Durner, V. ; Busch, D.H. ; Höfler, H. ; Ollert, M. ; Strom, T.M. ; Wolf, E. ; Neff, F. ; Hrabě de Angelis, M.
An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease.Hilber, B.H.J.
Klinisch-pathologische Bedeutung des Signalweges des Rezeptors des epidermalen Wachstumsfaktors (EGFR) beim Adenokarzinom des gastroösophagealen Übergangs Typ I (Barrett-Karzinom).Maier, S.K. ; Hahne, H. ; Moghaddas Gholami, A. ; Balluff, B. ; Meding, S. ; Schoene, C. ; Walch, A.K. ; Kuster, B.
Comprehensive identification of proteins from MALDI imaging.Wortmann, M. ; Schneider, M. ; Pircher, J. ; Hellfritsch, J. ; Aichler, M. ; Vegi, N. ; Koelle, P. ; Kuhlencordt, P. ; Walch, A.K. ; Pohl, U. ; Bornkamm, G.W. ; Conrad, M. ; Beck, H.
Combined deficiency in glutathione peroxidase 4 and vitamin E causes multi-organ thrombus formation and early death in mice.Bonzheim, I. ; Irmler, M. ; Klier-Richter, M. ; Steinhilber, J. ; Anastasov, N. ; Schafer, S. ; Adam, P. ; Beckers, J. ; Raffeld, M. ; Fend, F. ; Quintanilla-Martinez, L.
Identification of C/EBPβ target genes in ALK+ Anaplastic Large Cell Lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation.Lee, M.S. ; Marinoni, I. ; Irmler, M. ; Psaras, T. ; Honegger, J.B. ; Beschorner, R. ; Anastasov, N. ; Beckers, J. ; Theodoropoulou, M. ; Roncaroli, F. ; Pellegata, N.S.
Transcriptome analysis of MENX-associated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas.Schulz, S. ; Schmitt, S. ; Wimmer, R. ; Aichler, M. ; Eisenhofer, S. ; Lichtmannegger, J. ; Eberhagen, C. ; Artmann, R. ; Toókos, F. ; Walch, A.K. ; Krappmann, D. ; Brenner-Jan, C. ; Rust, C. ; Zischka, H.
Progressive stages of mitochondrial destruction caused by cell toxic bile salts.Richter, G.H.S. ; Fasan, A. ; Hauer, K. ; Grunewald, T.G.P. ; Berns, C. ; Rössler, S. ; Naumann, I. ; Staege, M.S. ; Fulda, S. ; Esposito, I. ; Burdach, S.
G-protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1.Taruttis, A. ; Wildgruber, M. ; Kosanke, K. ; Bézière, N. ; Licha, K. ; Haag, R. ; Aichler, M. ; Walch, A.K. ; Rummeny, E. ; Ntziachristos, V.
Multispectral optoacoustic tomography of myocardial infarction.Krebs, K.M. ; Böttinger, N. ; Huang, L.R. ; Chmielewski, M. ; Arzberger, S. ; Gasteiger, G. ; Jager, C. ; Schmitt, E. ; Bohne, F. ; Aichler, M. ; Uckert, W. ; Abken, H. ; Heikenwälder, M. ; Knolle, P. ; Protzer, U.
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.Ludyga, N. ; Englert, S. ; Pflieger, K. ; Rauser, S. ; Braselmann, H. ; Walch, A.K. ; Auer, G. ; Höfler, H. ; Aubele, M.
The impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) in human breast cancer.Azimzadeh, O. ; Sievert, W. ; Sarioglu, H. ; Yentrapalli, R. ; Barjaktarovic, Z. ; Sriharshan, A. ; Ueffing, M. ; Janik, D. ; Aichler, M. ; Atkinson, M.J. ; Multhoff, G. ; Tapio, S.
PPAR alpha: A novel radiation target in locally exposed Mus musculus heart revealed by quantitative proteomics.Tapfer, A. ; Braren, R. ; Bech, M. ; Willner, M. ; Zanette, I. ; Weitkamp, T. ; Trajkovic-Arsic, M. ; Siveke, J.T. ; Settles, M. ; Aichler, M. ; Walch, A.K. ; Pfeiffer, F.
X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.Aichler, M. ; Elsner, M. ; Ludyga, N. ; Feuchtinger, A. ; Zangen, V. ; Maier, S.K. ; Balluff, B. ; Schöne, C. ; Hierber, L. ; Braselmann, H. ; Meding, S. ; Rauser, S. ; Zischka, H. ; Aubele, M. ; Schmitt, M. ; Feith, M. ; Hauck, S.M. ; Ueffing, M. ; Langer, R. ; Kuester, B. ; Zitzelsberger, H. ; Höfler, H. ; Walch, A.K.
Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria.Vogel, K.U. ; Edelmann, S.L. ; Jeltsch, K. ; Bertossi, A. ; Heger, K. ; Heinz, G.A. ; Zöller, J. ; Warth, S.C. ; Höfig, K.P. ; Lohs, C. ; Neff, F. ; Kremmer, E. ; Schick, J. ; Repsilber, D. ; Geerlof, A. ; Blum, H. ; Wurst, W. ; Heikenwälder, M. ; Schmidt-Supprian, M. ; Heissmeyer, V.
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.Oetjen, J. ; Aichler, M. ; Trede, D. ; Strehlow, J. ; Berger, J. ; Heldmann, S. ; Becker, M. ; Gottschalk, M. ; Kobarg, J.H. ; Wirtz, S. ; Schiffler, S. ; Thiele, H. ; Walch, A.K. ; Maass, P. ; Alexandrov, T.
MRI-compatible pipeline for three-dimensional MALDI imaging mass spectrometry using PAXgene fixation.Occhi, G. ; Regazzo, D. ; Trivellin, G. ; Boaretto, F. ; Ciato, D. ; Bobisse, S. ; Ferasin, S. ; Cetani, F. ; Pardi, E. ; Korbonits, M. ; Pellegata, N.S. ; Sidarovich, V. ; Quattrone, A. ; Opocher, G. ; Mantero, F. ; Scaroni, C.
A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.Lee, M.S. ; Pellegata, N.S.
Folate receptor-mediated drug targeting: A possible strategy for nonfunctioning pituitary adenomas?Ludyga, N. ; Anastasov, N. ; Rosemann, M. ; Seiler, J. ; Lohmann, N. ; Braselmann, H. ; Mengele, K. ; Schmitt, M. ; Höfler, H. ; Aubele, M.
Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells.Schöne, C. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry in cancer research: Combining proteomic profiling and histological evaluation.Meding, S. ; Walch, A.K.
MALDI imaging mass spectrometry for direct tissue analysis.Müller, T.D. ; Lee, S.J. ; Jastroch, M. ; Kabra, D. ; Stemmer, K. ; Aichler, M. ; Abplanalp, B. ; Ananthakrishnan, G. ; Bhardwaj, N. ; Collins, S. ; Divanovic, S. ; Endele, M. ; Finan, B. ; Gao, Y. ; Habegger, K.M. ; Hembree, J. ; Heppner, K.M. ; Hofmann, S. ; Holland, J. ; Küchler, D. ; Kutschke, M. ; Krishna, R. ; Lehti, M. ; Oelkrug, R. ; Ottaway, N. ; Perez-Tilve, D. ; Raver, C. ; Walch, A.K. ; Schriever, S.C. ; Speakman, J. ; Tseng, Y.H. ; Diaz-Meco, M. ; Pfluger, P.T. ; Moscat, J. ; Tschöp, M.H.
P62 links β-adrenergic input to mitochondrial function and thermogenesis.Marinoni, I. ; Lee, M.S. ; Mountford, S. ; Perren, A. ; Bravi, I. ; Jennen, L. ; Feuchtinger, A. ; Drouin, J. ; Roncaroli, F. ; Pellegata, N.S.
Characterization of MENX-associated pituitary tumours.Bettstetter, M. ; Berezowska, S. ; Keller, G. ; Walch, A.K. ; Feuchtinger, A. ; Slotta-Huspenina, J. ; Feith, M. ; Drecoll, E. ; Höfler, H. ; Langer, R.
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: Loss of PTEN is associated with worse clinical outcome.Hauer, K. ; Calzada-Wack, J. ; Steiger, K. ; Grunewald, T.G. ; Baumhoer, D. ; Plehm, S. ; Buch, T. ; Prazeres da Costa, O. ; Esposito, I. ; Burdach, S. ; Richter, G.H.
DKK2 mediates osteolysis, invasiveness and metastatic spread in Ewing sarcoma.