All Publications since 2000
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Leinhäuser, I. ; Höfig, I. ; Anastasov, N. ; Beuschlein, F. ; Mannelli, M. ; Atkinson, M.J. ; Pellegata, N.S.
The Bone morphogenic protein 7 (Bmp7) plays a pro-tumorigenic role in pheochromocytoma.Kandemir, M. ; Feuchtinger, A. ; Walch, A.K. ; Hamprecht, F.A.
Digital pathology: Multiple instance learning can detect Barrett's cancer.Huber, M. ; Falkenberg, N. ; Schmitt, M. ; Braselmann, H. ; Mall, R. ; Jakovac, M. ; Walch, A.K. ; Höfler, H. ; Aubele, M.
uPAR and its interaction partners: potential new therapy targets in triple negative breast cancer.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Höfig, I. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Höfig, I. ; Falkenberg, N. ; Rosemann, M. ; Szumielewski, J. ; Richter, S. ; Atkinson, M.J. ; Aubele, M. ; Anastasov, N.
Relevance of 3D-microtissues to investigate the therapeutic oncogenes HER2 and PTK6 in breast cancer.Pellegata, N.S. ; Molatore, S. ; Neff, F. ; Irmler, M. ; Pulz, E. ; Roncaroli, F.
p27 is a haploinsufficient tumor suppressor in MENX rats and this associates with the development of invasive medullary thyroid carcinoma.Lee, M.S. ; Gaertner, F.C. ; Pellegata, N.S.
Regulation of norepinephrine transporter expression in pheochromocytoma by dual PI3K/mTOR inhibition.Leinhäuser, I. ; Atkinson, M.J. ; Pellegata, N.S.
The transcription factor Phox2a plays a pro-tumorigenic role in pheochromocytoma.Becker, L. ; Kling, E. ; Schiller, E. ; Zeh, R. ; Schrewe, A. ; Hölter, S.M. ; Mossbrugger, I. ; Calzada-Wack, J. ; Strecker, V. ; Wittig, I. ; Dumitru, I. ; Wenz, T. ; Bender, A. ; Aichler, M. ; Janik, D. ; Neff, F. ; Walch, A.K. ; Quintanilla-Fend, L. ; Floß, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Meitinger, T. ; Prokisch, H. ; Hrabě de Angelis, M. ; Klopstock, T.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Maier, S.K.
Towards comprehensive identification of proteins from MALDI imaging.Kempf, S.J. ; Casciati, A. ; Buratovic, S. ; Janik, D. ; von Toerne, C. ; Ueffing, M. ; Neff, F. ; Mörtl, S. ; Stenerlöw, B. ; Saran, A. ; Atkinson, M.J. ; Eriksson, P. ; Pazzaglia, S. ; Tapio, S.
The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation.Stering, K.
Etablierung der PLA-Technik an Paraffingewebe von Mammakarzinomen: Identifizierung von PTK6 co-exprimierten Proteinen und ihre medizinische Relevanz.Friedmann Angeli, J.P.F. ; Schneider, M. ; Proneth, B. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Hammond, V.J. ; Herbach, N. ; Aichler, M. ; Walch, A.K. ; Eggenhofer, E. ; Basavarajappa, D. ; Rådmark, O. ; Kobayashi, S. ; Seibt, T. ; Beck, H. ; Neff, F. ; Esposito, I. ; Wanke, R. ; Förster, H. ; Yefremova, O. ; Heinrichmeyer, M. ; Bornkamm, G.W. ; Geissler, E.K. ; Thomas, S.B. ; Stockwell, B.R. ; O'Donnell, V.B. ; Kagan, V.E. ; Schick, J. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Baumgart, S. ; Chen, N. ; Siveke, J.T. ; König, A.O. ; Zhang, J. ; Singh, S.K. ; Wolf, E. ; Bartkuhn, M. ; Esposito, I. ; Heßmann, E. ; Reinecke, J. ; Nikorowitsch, J. ; Brunner, M. ; Singh, G.P. ; Fernández-Zapico, M.E. ; Smyrk, T.C. ; Bamlet, W.R. ; Eilers, M. ; Neeße, A. ; Gress, T.M. ; Billadeau, D.D. ; Tuveson, D.A. ; Urrutia, R.A. ; Ellenrieder, V.
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.Thor, T. ; Künkele, A. ; Pajtler, K.W. ; Wefers, A.K. ; Stephan, H. ; Mestdagh, P. ; Heukamp, L. ; Hartmann, W. ; Vandesompele, J. ; Sadowski, N. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Horsch, M. ; Calzada-Wack, J. ; Klein-Rodewald, T. ; Rácz, I. ; Zimmer, A. ; Beckers, J. ; Neff, F. ; Klopstock, T. ; de Antonellis, P. ; Zollo, M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Schüller, U. ; Hrabě de Angelis, M. ; Eggert, A. ; Schramm, A. ; Schulte, J.H.
MiR-34a deficiency accelerates medulloblastoma formation in vivo.Keller, J. ; Catala-Lehnen, P. ; Huebner, A.K. ; Jeschke, A. ; Heckt, T. ; Lueth, A. ; Krause, M. ; Koehne, T. ; Albers, J. ; Schulze, J. ; Schilling, S. ; Haberland, M. ; Denninger, H. ; Neven, M. ; Hermans-Borgmeyer, I. ; Streichert, T. ; Breer, S. ; Barvencik, F. ; Levkau, B. ; Rathkolb, B. ; Wolf, E. ; Calzada-Wack, J. ; Neff, F. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Klutmann, S. ; Tsourdi, E. ; Hofbauer, L.C. ; Kleuser, B. ; Chun, J. ; Schinke, T. ; Amling, M.
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.Aichler, M. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Proteomic and metabolic prediction of response to therapy in gastric cancer.Huber, K. ; Feuchtinger, A. ; Borgmann, D.M. ; Li, Z. ; Aichler, M. ; Hauck, S.M. ; Zitzelsberger, H. ; Schwaiger, M. ; Keller, U. ; Walch, A.K.
A novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.Gegg, M. ; Böttcher, A. ; Burtscher, I. ; Hasenöder, S. ; van Campenhout, C.A. ; Aichler, M. ; Walch, A.K. ; Grant, S.G. ; Lickert, H.
Flattop regulates basal body docking and positioning in mono- and multiciliated cells.Balluff, B. ; Frese, C.K. ; Maier, S.K. ; Schöne, C. ; Kuster, B. ; Schmitt, M. ; Aubele, M. ; Höfler, H. ; Deelder, A.M. ; Heck, A.J. ; Hogendoorn, P.C.W. ; Morreau, J. ; Altelaar, A.F. ; Walch, A.K. ; McDonnell, L.A.
De novo discovery of phenotypic intra-tumor heterogeneity using imaging mass spectrometry.Aichler, M. ; Motschmann, M. ; Jütting, U. ; Luber, B. ; Becker, K. ; Ott, K. ; Lordick, F. ; Langer, R. ; Feith, M. ; Siewert, J.R. ; Walch, A.K.
Epidermal Growth Factor Receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy.Feuchtinger, A. ; Stiehler, T. ; Jütting, U. ; Marjanovic, G. ; Luber, B. ; Langer, R. ; Walch, A.K.
Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma.Maier, S.K. ; Bashkueva, K. ; Rösli, C. ; Skerra, A. ; Kuster, B.
PAS-cal: A repetitive peptide sequence calibration standard for MALDI mass spectrometry.Weber, E. ; Finsterbusch, K. ; Lindquist, R. ; Nair, S. ; Lienenklaus, S. ; Gekara, N.O. ; Janik, D. ; Weiss, S. ; Kalinke, U. ; Overby, A.K. ; Kröger, A.
Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local anti-viral response.Kraus, P. ; Sivakamasundari, V. ; Yu, H.B. ; Xing, X. ; Lim, S.L. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Janas, E. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Adamski, J. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Eickelberg, O. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Lufkin, T. ; Stanton, L.W.
Pleiotropic functions for transcription factor Zscan10.Rosemann, M. ; Gonzalez-Vasconcellos, I. ; Domke, T. ; Kuosaite, V. ; Schneider, R. ; Kremer, M. ; Favor, J. ; Nathrath, M. ; Atkinson, M.J.
A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.Ehninger, D. ; Neff, F. ; Xie, K.
Longevity, aging and rapamycin.Slotta-Huspenina, J. ; Becker, K.F. ; Feith, M. ; Walch, A.K. ; Langer, R.
Heat Shock Protein 90 (HSP90) and Her2 in adenocarcinomas of the esophagus.Schmitt, S. ; Schulz, S. ; Schropp, E.-M. ; Eberhagen, C. ; Simmons, A. ; Beisker, W. ; Aichler, M. ; Zischka, H.
Why to compare absolute numbers of mitochondria.Arabi, L. ; Gsponer, J.R. ; Smida, J. ; Nathrath, M. ; Perrina, V. ; Jundt, G. ; Ruiz, C. ; Quagliata, L. ; Baumhoer, D.
Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma - reasons and consequences.Buck, A. ; Walch, A.K.
In situ drug and metabolite analyzes in biological and clinical research by MALDI MS imaging.Heimesaat, M.M. ; Fischer, A. ; Plickert, R. ; Wiedemann, T. ; Loddenkemper, C. ; Göbel, U.B. ; Bereswill, S. ; Rieder, G.
Helicobacter pylori induced gastric immunopathology is associated with distinct microbiota changes in the large intestines of long-term infected Mongolian gerbils.Graf, N. ; Li, Z. ; Herrmann, K. ; Weh, D. ; Aichler, M. ; Slawska, J. ; Walch, A.K. ; Peschel, C. ; Schwaiger, M. ; Buck, A.K. ; Dechow, T. ; Keller, U.
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma.Longuini, V.C. ; Lourenco-Jr, D.M. ; Sekiya, T. ; Meirelles, O.D. ; Goncalves, T.D. ; Coutinho, F.L. ; Francisco, G. ; Osaki, L.H. ; Chammas, R. ; Alves, V.A. ; Siqueira, S.A. ; Schlesinger, D. ; Naslavsky, M.S. ; Zatz, M. ; Duarte, Y.A. ; Lebrao, M.L. ; Gama, P. ; Lee, M.S. ; Molatore, S. ; Pereira, M.A. ; Jallad, R.S. ; Bronstein, M.D. ; Cunha Neto, M.B. ; Liberman, B. ; Fragoso, M.C. ; Toledo, S.P. ; Pellegata, N.S. ; Toledo, R.A.
Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.Zumbrennen-Bullough, K.B. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Calzada-Wack, J. ; Mossbrugger, I. ; Quintanilla-Fend, L. ; Rácz, I. ; Rathkolb, B. ; Klopstock, T. ; Wurst, W. ; Zimmer, A. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Romney, S.J. ; Leibold, E.A.
Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments.Poos, K. ; Smida, J. ; Nathrath, M. ; Maugg, D. ; Baumhoer, D. ; Neumann, A. ; Korsching, E.
Structuring osteosarcoma knowledge: An osteosarcoma-gene association database based on literature mining and manual annotation.Gorzolka, K. ; Walch, A.K.
MALDI mass spectrometry imaging of formalin-fixed paraffin-embedded tissues in clinical research.Huber, K. ; Aichler, M. ; Sun, N. ; Buck, A. ; Li, Z. ; Fernandez, I.E. ; Hauck, S.M. ; Zitzelsberger, H. ; Eickelberg, O. ; Janssen, K.P. ; Keller, U. ; Walch, A.K.
A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.Meier, R. ; Braren, R. ; Kosanke, Y. ; Bussemer, J. ; Neff, F. ; Wildgruber, M. ; Schwarzenböck, S. ; Frank, A. ; Haller, B. ; Hohlbaum, A.M. ; Schwaiger, M. ; Gille, H. ; Rummeny, E.J. ; Beer, A.J.
Multimodality multiparametric imaging of early tumor response to a novel antiangiogenic therapy based on anticalins.Dekker, T.J. ; Balluff, B.D. ; Jones, E.A. ; Schöne, C.D. ; Schmitt, M. ; Aubele, M. ; Kroep, J.R. ; Smit, V.T. ; Tollenaar, R.A. ; Mesker, W.E. ; Walch, A.K. ; McDonnell, L.A.
Multicenter Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma.Jin, S. ; Kim, J. ; Willert, T. ; Klein-Rodewald, T. ; Garcia-Dominguez, M. ; Mosqueira, M. ; Fink, R. ; Esposito, I. ; Hofbauer, L.C. ; Charnay, P. ; Kieslinger, M.
Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.Ewald, F. ; Annemann, M. ; Pils, M.C. ; Plaza-Sirvent, C. ; Neff, F. ; Erck, C. ; Reinhold, D. ; Schmitz, I.
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.Bézière, N. ; von Schacky, C. ; Kosanke, Y. ; Kimm, M. ; Nunes, A. ; Licha, K. ; Aichler, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Meier, R.
Optoacoustic imaging and staging of arthritic inflammation.Malinowsky, K. ; Nitsche, U. ; Janssen, K.P. ; Bader, F.G. ; Späth, C. ; Drecoll, E. ; Keller, G. ; Höfler, H. ; Slotta-Huspenina, J. ; Becker, K.F.
Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer.Sekiya, T. ; Bronstein, M.D. ; Benfini, K. ; Longuini, V.C. ; Jallad, R.S. ; Machado, M.C. ; Goncalves, T.D. ; Osaki, L.H. ; Higashi, L. ; Lima-Jr, J.V. ; Kater, C.E. ; Lee, M. ; Molatore, S. ; Francisco, G. ; Chammas, R. ; Naslavsky, M. ; Schlesinger, D. ; Gama, P. ; Duarte, Y.A. ; Lebrao, M.L. ; Zatz, M. ; Meirelles, O. ; Liberman, B. ; Fragoso, M.C. ; Toledo, S.P. ; Pellegata, N.S. ; Toledo, R.A.
p27 variant and corticotropinoma susceptibility: A genetic and in vitro study.Kucharska, J. ; del Río, P. ; Arango-González, B. ; Gorza, M. ; Feuchtinger, A. ; Hauck, S.M. ; Ueffing, M.
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.Niedzielska, M. ; Bodendorfer, B. ; Münch, S. ; Eichner, A. ; Derigs, M. ; da Costa, O.P. ; Schweizer, A. ; Neff, F. ; Nitschke, L. ; Sparwasser, T. ; Keyse, S.M. ; Lang, R.
Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-Like Receptor (TLR)-induced cytokine production.Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E. ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S. ; Reichert, A.S. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T. ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Avitzur, Y. ; Guo, C. ; Mastropaolo, L.A. ; Bahrami, E. ; Chen, H. ; Zhao, Z. ; Elkadri, A. ; Dhillon, S. ; Murchie, R. ; Fattouh, R. ; Huynh, H. ; Walker, J.L. ; Wales, P.W. ; Cutz, E. ; Kakuta, Y. ; Dudley, J. ; Kammermeier, J. ; Powrie, F. ; Shah, N. ; Walz, C. ; Nathrath, M. ; Kotlarz, D. ; Puchaka, J. ; Krieger, J. ; Racek, T. ; Kirchner, T. ; Walters, T.D. ; Brumell, J.H. ; Griffiths, A.M. ; Rezaei, N. ; Rashtian, P. ; Najafi, M. ; Monajemzadeh, M. ; Pelsue, S. ; McGovern, D.P. ; Uhlig, H.H. ; Schadt, E. ; Klein, C. ; Snapper, S.B. ; Muise, A.M.
Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.Sun, N. ; Ly, A. ; Meding, S. ; Witting, M. ; Hauck, S.M. ; Ueffing, M. ; Schmitt-Kopplin, P. ; Aichler, M. ; Walch, A.K.
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry.Li, Z. ; Herrmann, K. ; Pirsig, S. ; Philipp-Abbrederis, K. ; Henninger, M. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Beer, A.J. ; Ringshausen, I. ; Pomykala, K.L. ; Scheidhauer, K. ; Schwaiger, M. ; Keller, U. ; Buck, A.K.
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma.Wildgruber, M. ; Bielicki, I. ; Aichler, M. ; Kosanke, K. ; Feuchtinger, A. ; Settles, M. ; Onthank, D.C. ; Cesati, R.R. ; Robinson, S.P. ; Huber, A.M. ; Rummeny, E.J. ; Walch, A.K. ; Botnar, R.M.
Assessment of myocardial infarction and post-infarction scar remodeling with an elastin-specific magnetic resonance agent.McDonnell, L.A. ; Walch, A.K. ; Stoeckli, M. ; Corthals, G.L.
MSiMass list: A public database of identifications for protein MALDI MSI.Baumhoer, D. ; Brunner, P. ; Eppenberger-Castori, S. ; Smida, J. ; Nathrath, M. ; Jundt, G.
Osteosarcomas of the jaws differ from their peripheral counterparts and require a distinct treatment approach. Experiences from the DOESAK registry.Aichler, M. ; Walch, A.K.
In brief: The (molecular) pathogenesis of Barrett's oesophagus.