Staff members

Dr. Simon Dreher
Scientist

Phone: +49 7071 29-85676
E-mail

Research interests: 

  • Diabetology
  • Signaling-Pathways
  • Metabolism
  • Exercise-Intervention
  • Cell-Biology
  • Immunology
  • Tissue-Engineering

Education and career: 

since 01/21         Scientist at the Department for Molecular Diabetology,

                           Institute for clinical chemistry and pathobiogemistry,

                           Universtity Hospital Tübingen

03/15-12/20        Employed as research associate at

                           Ruperto Carola University Heidelberg,

                           Research Center for Experimental Orthopaedics,

                           Orthopedic University Hospital Heidelberg

04/15-06/20         PhD student at the Ruperto Carola University Heidelberg (Dr.rer.nat.)

06/20                   PhD (Dr.rer.nat.) magna cum laude

10/12-07/14         Molecular Cell Biology / Immunology and Parasitology at

                            Eberhard Karls University in Tübingen (M.Sc.)

10/09-09/12         Biology at Eberhard Karls University in Tübingen (B.Sc.)

Prizes and Awards: 

  • The Robert Mathys Prize for Best Student Oral Presentation: Dreher, S.I.: Hypertrophy-associated regulation of RUNX3 and MEF2C during chondrogenesis of human mesenchymal progenitor cells, eCM XVIII: Cartilage & Disc: Repair and Regeneration 25th – 28th June 2018, Davos, Switzerland

Current projects: 

Micro RNAs (miRs) and signaling pathways in exercise response.

Publications: 

Dreher, S.I., Fischer, J., Walker, T., Diederichs, S., and Richter, W. (2020). Significance of MEF2C and RUNX3 regulation for endochondral differentiation of human mesenchymal progenitor cells. Front Cell Dev Biol. 2020 Mar 4;8:81. doi: 10.3389/fcell.2020.00081. eCollection 2020. https://pubmed.ncbi.nlm.nih.gov/32195247/

Diederichs, S., Tonnier, V., Marz, M., Dreher, S.I., Geisbusch, A., and Richter, W. (2019). Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy. Cell Mol Life Sci. 2019 Oct;76(19):3875-3889. doi: 10.1007/s00018-019-03099-0. Epub 2019 Apr 12. https://pubmed.ncbi.nlm.nih.gov/30980110/

Melnik, S., Gabler, J., Dreher, S.I. Hecht, H., Hofmann, N., Großner, T., Richter, W. (2020/21). MiR-218 affects hypertrophic differentiation of human mesenchymal stromal cells during chondrogenesis via targeting RUNX2, MEF2C, and COL10A1. Stem Cell Res Ther. 2020 Dec 10;11(1):532. doi: 10.1186/s13287-020-02026-6 https://pubmed.ncbi.nlm.nih.gov/33303006/