Staff members

Dr. Simon Dreher

Phone: +49 7071 29-85676

Research interests: 

  • Diabetology
  • Signaling-Pathways
  • Metabolism
  • Exercise-Intervention
  • Cell-Biology
  • Immunology
  • Tissue-Engineering

Education and career: 

since 01/21         Scientist at the Department for Molecular Diabetology,

                           Institute for clinical chemistry and pathobiogemistry,

                           Universtity Hospital Tübingen

03/15-12/20        Employed as research associate at

                           Ruperto Carola University Heidelberg,

                           Research Center for Experimental Orthopaedics,

                           Orthopedic University Hospital Heidelberg

04/15-06/20         PhD student at the Ruperto Carola University Heidelberg (Dr.rer.nat.)

06/20                   PhD (Dr.rer.nat.) magna cum laude

10/12-07/14         Molecular Cell Biology / Immunology and Parasitology at

                            Eberhard Karls University in Tübingen (M.Sc.)

10/09-09/12         Biology at Eberhard Karls University in Tübingen (B.Sc.)

Prizes and Awards: 

  • The Robert Mathys Prize for Best Student Oral Presentation: Dreher, S.I.: Hypertrophy-associated regulation of RUNX3 and MEF2C during chondrogenesis of human mesenchymal progenitor cells, eCM XVIII: Cartilage & Disc: Repair and Regeneration 25th – 28th June 2018, Davos, Switzerland

Current projects: 

Micro RNAs (miRs) and signaling pathways in exercise response.


Dreher, S.I., Fischer, J., Walker, T., Diederichs, S., and Richter, W. (2020). Significance of MEF2C and RUNX3 regulation for endochondral differentiation of human mesenchymal progenitor cells. Front Cell Dev Biol. 2020 Mar 4;8:81. doi: 10.3389/fcell.2020.00081. eCollection 2020.

Diederichs, S., Tonnier, V., Marz, M., Dreher, S.I., Geisbusch, A., and Richter, W. (2019). Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy. Cell Mol Life Sci. 2019 Oct;76(19):3875-3889. doi: 10.1007/s00018-019-03099-0. Epub 2019 Apr 12.

Melnik, S., Gabler, J., Dreher, S.I. Hecht, H., Hofmann, N., Großner, T., Richter, W. (2020/21). MiR-218 affects hypertrophic differentiation of human mesenchymal stromal cells during chondrogenesis via targeting RUNX2, MEF2C, and COL10A1. Stem Cell Res Ther. 2020 Dec 10;11(1):532. doi: 10.1186/s13287-020-02026-6