Reizdarm - Darm

Senior Scientist at the Research Unit Analytical Biogeochemistry

Dr. Alesia Walker

Research Area

Alesia Walker’s research focuses primarily on non-targeted metabolomics. She uses LC-coupled high-resolution mass spectrometry to study host-microbiota interactions, with an emphasis on diet-related metabolic disorders and inflammatory bowel diseases. By working with large population cohorts, Alesia enhances the statistical power and clinical relevance of her findings. Her work in developing analytical methodologies, both on a global scale and with a focus on specific metabolite classes or lipids, aims to better understand how microbial metabolites affect host health. This often leads to the discovery of previously unknown metabolites.

In addition to providing metabolomics expertise and high-quality data to collaborative research partners and the scientific community, Alesia also shares her knowledge with the next generation of researchers.

Fields of Work and Expertise

Metabolomics LC-MS Human Microbiome Inflammatory Bowel Diseases

Professional Background

Since 2018

Senior Scientist at the Research Unit Analytical Biogeochemistry, Helmholtz Munich

2013 - 2018

Postdoctoral Researcher at Helmholtz Munich

2013

Ph.D. in Analytical Chemistry at the Technical University Munich

2009

M.Sc. in Nutrition Science at the Technical University of Munich

Projects and Fundings

  • ANR DFG 2020 NLE PhaStGut - Mechanisms underlying bacteriophages and bacteria stable coexistence and its consequences on gut microbiome function
  • DFG Research Unit miTarget 5042 - The microbiome as a therapeutic target in inflammatory bowel diseases
  • DECODE - Defining stratification of patients with C3 Glomerulopathies/immune complex-mediated glomerular diseases for better diagnosis and tailored treatment
  • APROSUS - Microbiome-derived asthma and allergy protective substances for prevention

Highlight Publications

Best, L., Dost, T., Esser, D., Flor, S., Gamarra, A. M., Haase, M., Kadibalban, A. S., Marinos, G., Walker, A., Zimmermann, J., Simon, R., Schmidt, S., Taubenheim, J., Künzel, S., Häsler, R., Franzenburg, S., Groth, M., Waschina, S., Rosenstiel, P., ... Kaleta, C.

Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice.

Krause, F. F., Mangold, K. I., Ruppert, A. L., Leister, H., Hellhund-Zingel, A., Lopez Krol, A., ... & Visekruna, A.

Clostridium sporogenes-derived metabolites protect mice against colonic inflammation.

Marques dos Santos, M., Pivniouk, V., Rankl, B., Walker, A., Pagani, G., Hertkorn, N., Schmitt-Kopplin, P., Müller, C., Bracher, F., Merl-Pham, J., Hauck, S. M., Schloter, M., Michael, A. N., Anderson, D., Honeker, L., Gozdz, J., Pivniouk, O., Ober, C., Holbreich, M., ... Vercelli, D.

Asthma-protective agents in dust from traditional farm environments.

Networks and Affiliations