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Tower ALI System - with laser detection

 

Exposing in vitro cells at the air liquid interface (ALI) is a powerful tool to investigate the cellular response to different aerosols, such as ultrafine particles or allergen extracts, but is usually limited to very specific sizes or solutions. Therefore, a new ALI System is developed which allows in vitro cell exposure to a wide range of particles, including nanoparticle, fibers, pollen as well as mixtures of different sizes. The particles/fibers are directly used, without changing the chemical and physical properties by e.g. dispersing them in a solution. Additionally, particles and fibers > 0.5 µm can be directly quantified by using a newly developed laser detection approach.

Scientist involved: Elias Zimmermann

Collaboration with Dr Robert Irsig, Photonion GmbH

Tower ALI System - with laser detection

 

Exposing in vitro cells at the air liquid interface (ALI) is a powerful tool to investigate the cellular response to different aerosols, such as ultrafine particles or allergen extracts, but is usually limited to very specific sizes or solutions. Therefore, a new ALI System is developed which allows in vitro cell exposure to a wide range of particles, including nanoparticle, fibers, pollen as well as mixtures of different sizes. The particles/fibers are directly used, without changing the chemical and physical properties by e.g. dispersing them in a solution. Additionally, particles and fibers > 0.5 µm can be directly quantified by using a newly developed laser detection approach.

Scientist involved: Elias Zimmermann

Collaboration with Dr Robert Irsig, Photonion GmbH

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