Spatial Transcriptomics
Spatial Transcriptomics as a cutting-edge application using 10x Genomics CytAssist / Visium and Xenium in situ technologies is also in our services portfolio.
It is a molecular profiling method that allows scientists to measure the gene activity in a tissue sample and map where the activity is occurring. Defining the spatial distribution of mRNA molecules uncovers cellular heterogeneity in tissues, tumors, and immune cells, as well as determines the subcellular distribution of transcripts in various conditions. This information provides a unique opportunity to decipher both the cellular and subcellular architecture in tissues and individual cells.
Through a collaborative, cross-cores effort with Core Facility Genomics (see more here), we offer seamless support from tissue preparation to data analysis, empowering researchers with both single-cell and subcellular spatially resolved gene expression data for their studies.
The 10X Genomics Xenium Analyzer, our state-of-the-art instrument, swiftly generates data immediately after the run. Whether your tissues are FFPE or fresh frozen (FF), the processing preserves structural integrity, facilitating additional assays e.g. Hematoxylin and Eosin (H&E), Immunofluorescence (IF) or Visium on the same sample.
The 10X Genomics CytAssist / Visium is a state-of-the art system that enables spatial transcriptomics by transferring mRNA from FFPE or FF tissue on standard histology slides to barcoded Visium slides, ensuring compatibility with pathology workflows. This process preserves tissue morphology while enabling spatially resolved gene expression analysis, seamlessly integrating with downstream sequencing and bioinformatics pipelines.
We are happy to discuss your project needs, please email us for an in-depth discussion of your spatial transcriptomics work at the earliest possible planning stages.
For detailed information about the “Xenium Sample Preparation Workflow,” please click on the button below.
Spatial Transcriptomics as a cutting-edge application using 10x Genomics CytAssist / Visium and Xenium in situ technologies is also in our services portfolio.
It is a molecular profiling method that allows scientists to measure the gene activity in a tissue sample and map where the activity is occurring. Defining the spatial distribution of mRNA molecules uncovers cellular heterogeneity in tissues, tumors, and immune cells, as well as determines the subcellular distribution of transcripts in various conditions. This information provides a unique opportunity to decipher both the cellular and subcellular architecture in tissues and individual cells.
Through a collaborative, cross-cores effort with Core Facility Genomics (see more here), we offer seamless support from tissue preparation to data analysis, empowering researchers with both single-cell and subcellular spatially resolved gene expression data for their studies.
The 10X Genomics Xenium Analyzer, our state-of-the-art instrument, swiftly generates data immediately after the run. Whether your tissues are FFPE or fresh frozen (FF), the processing preserves structural integrity, facilitating additional assays e.g. Hematoxylin and Eosin (H&E), Immunofluorescence (IF) or Visium on the same sample.
The 10X Genomics CytAssist / Visium is a state-of-the art system that enables spatial transcriptomics by transferring mRNA from FFPE or FF tissue on standard histology slides to barcoded Visium slides, ensuring compatibility with pathology workflows. This process preserves tissue morphology while enabling spatially resolved gene expression analysis, seamlessly integrating with downstream sequencing and bioinformatics pipelines.
We are happy to discuss your project needs, please email us for an in-depth discussion of your spatial transcriptomics work at the earliest possible planning stages.
For detailed information about the “Xenium Sample Preparation Workflow,” please click on the button below.
- 10X Genomics Xenium Analyzer
- 10X Genomics Visium CytAssist
