Human Microbiomes
We aim to understand the functional basis of health-promoting microbes within the human microbiome, focusing on barrier organs like the skin and respiratory system, as well as the intestinal tract. Using data form clinical as well as cohort based studies we aim to identify core microbiota that contribute to health-promoting functions. These microorganisms are isolated via targeted isolation-based cultivation techniques and evaluated in vitro for their functional potential, which is further validated using cell culture and animal models. Based on microbial geno- and phenotypes, we will propose strategies to enhance the abundance and activity of these beneficial microbiota, particularly under dysbiotic conditions.
Research Focus
We aim to understand the functional basis of health-promoting microbes within the human microbiome, focusing on barrier organs like the skin and respiratory system, as well as the intestinal tract. Using data form clinical as well as cohort based studies we aim to identify core microbiota that contribute to health-promoting functions. These microorganisms are isolated via targeted isolation-based cultivation techniques and evaluated in vitro for their functional potential, which is further validated using cell culture and animal models. Based on microbial geno- and phenotypes, we will propose strategies to enhance the abundance and activity of these beneficial microbiota, particularly under dysbiotic conditions.
Research Focus
