Publications
2025 Oncogene Oncogene 44:336 (2025)
Correction: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
2025 Scientific Article in Redox Biology Redox Biol. 80:103503 (2025)
Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition.
2025 Review in FEBS Journal, The FEBS J., DOI: 10.1111/febs.17411 (2025)
Protective effects of neutrophil serine protease inhibition against ischemia-reperfusion injury in lung or heart transplantation.
2025 Review in Appetite Appetite 207:107840 (2025)
Best practices for including sex as a variable in appetite research.
2025 Review in Zeitschrift für Gerontologie und Geriatrie Z. Gerontol. Geriatr. 58, 85-90 (2025)
Physiologische und pathophysiologische Veränderungen der alternden Lunge.
2025 Scientific Article in The journal of allergy and clinical immunology. In practice J. Allergy Clin. Immunol. Pract., DOI: 10.1016/j.jaip.2025.01.010 (2025)
Mucus Plug Score predicts clinical and pulmonary function response to biologic therapy in patients with severe Asthma.
2025 Scientific Article in Aerosol Science and Technology Aerosol Sci. Technol., DOI: 10.1080/02786826.2024.2442524 (2025)
Cellular responses of lung cells cultured at an air-liquid interface are influenced by spatial nanoparticle deposition patterns in an in vitro aerosol exposure system.
2025 Review in World Journal of Experimental Medicine World J. Exp. Med. 15:100402 (2025)
Alcohol and alcoholism associated neurological disorders: Current updates in a global perspective and recent recommendations.
2025 Review in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 72, 16-31 (2025)
Precision-cut lung slices: Emerging tools for preclinical and translational lung research an official american thoracic society workshop report.
Lecture Notes in Computer Science In: (Computer Vision – ECCV 2024). Gewerbestrasse 11, Cham, Ch-6330, Switzerland: Springer International Publishing Ag, 2025. 413-430 (Lect. Notes Comput. Sc. ; 15144)
Fast context-based low-light image enhancement via neural implicit representations.
2025 Scientific Article in Human Gene Hum. Gene 43:201361 (2025)
Exploring the relationship between ERCC1 polymorphisms and colorectal cancer risk: Insights from an in-depth meta-analysis.
2025 Scientific Article in Avian Pathology Avian Pathol. 54, 40-49 (2025)
The first report and biological characterization of Avian Orthoavulavirus 16 in wild migratory waterfowl and domestic poultry in China reveal a potential threat to birds.
2024 Scientific Article in Research Square Research Square, DOI: 10.21203/rs.3.rs-5046381/v1 (2024)
Topographic atlas of cell states identifies regional gene expression in the adult human lung.
In: Bio-Nano Interfaces: Perspectives, Properties, and Applications. 2024. 795-818
Colloidal stability and surface chemistry are key factors for the composition of the protein corona of inorganic gold nanoparticles.
In: Bio-Nano Interfaces: Perspectives, Properties, and Applications. 2024. 1019-1032
In vivo integrity of polymer-coated gold nanoparticles.
In: Bio-Nano Interfaces: Perspectives, Properties, and Applications. 2024. 381-396
Multifunctional nanoparticles for dual imaging.
2024 Scientific Article in Journal of Aerosol Science J. Aerosol Sci. 181:106425 (2024)
Aerosol dosimetry in the whole conducting zone of a murine left-lung using CF-PD and LSFM images.
2024 Editorial in ERJ Open Research ERJ Open Res. 10:00659-2024 (2024)
Early career member highlights from the 22nd ERS Lung Science Conference: Development of chronic lung diseases - from life-spanning mechanisms to preventive therapy.
2024 Review in Nature Methods Nat. Methods, DOI: 10.1038/s41592-024-02532-y (2024)
Considerations for building and using integrated single-cell atlases.
2024 Scientific Article in Nano Letters Nano Lett. 24, 15683-15692 (2024)
Molecular dynamics simulations elucidate the molecular organization of poly(beta-amino ester) based polyplexes for siRNA delivery.
2024 Editorial in Breathe Breathe 20:240175 (2024)
The more stars, the brighter! Interview with the ECM award winner 2023.
2024 Scientific Article in Nature biomedical engineering Nat. Bio. Eng., DOI: 10.1038/s41551-024-01273-9 (2024)
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.
2024 Editorial in European Respiratory Journal Eur. Respir. J. 64:2401531 (2024)
A breath of the future: A novel human model for COPD and beyond.
2024 Scientific Article in Cell Host & Microbe Cell Host Microbe 32, 2112-2130.e10 (2024)
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19.
2024 Scientific Article in Nature Communications Nat. Commun. 15:10138 (2024)
LungVis 1.0: An automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages.
2024 Scientific Article in ACS Nano ACS Nano 18, 33168−33180 (2024)
Advanced nanoplatform mediated by CRISPR-Cas9 and aggregation-induced emission photosensitizers to boost cancer theranostics.
2024 Scientific Article in Nature Methods Nat. Methods 21, 2260–2270 (2024)
Probe set selection for targeted spatial transcriptomics.
2024 Scientific Article in Bioinformatics Bioinformatics 40:btae609 (2024)
Cluster-efficient pangenome graph construction with nf-core/pangenome.
2024 Scientific Article in Cellular & Molecular Immunology Cell. Mol. Immunol., DOI: 10.1038/s41423-024-01219-w (2024)
CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells.
2024 Scientific Article in Oncogene Oncogene, DOI: 10.1038/s41388-024-03141-x (2024)
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
2024 Scientific Article in JCI insight JCI insight 9:e180239 (2024)
Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD.
2024 Scientific Article in Microbiology and Immunology Microbiol. Immunol. 68, 399-405 (2024)
First detection and biological characterization of an avian metaavulavirus 8 isolated from a migratory swan goose in Qinghai Lake, Northwest China.
2024 Scientific Article in JCI insight JCI insight 9:e168889 (2024)
Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis.
2024 Review in Non-coding RNA Non-coding RNA 10:50 (2024)
Non-coding RNA as a biomarker in lung cancer.
2024 Review in Microorganisms Microorganisms 12:2030 (2024)
Interplay between lung diseases and viral infections: A comprehensive review.
2024 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 20, 629–630 (2024)
The role of DNA damage in diabetic complications.
2024 Scientific Article in Nature medicine Nat. Med., DOI: 10.1038/s41591-024-03214-0 (2024)
An open-source framework for end-to-end analysis of electronic health record data.
2024 Scientific Article in Transplantation Transplantation, DOI: 10.1097/TP.0000000000005189 (2024)
Characterization of baseline lung allograft dysfunction in single lung transplant recipients.
2024 Editorial in European Respiratory Journal Eur. Respir. J. 64:2400921 (2024)
COPD-iNET: A call to the lung community for action to combat the global epidemic of COPD.
2024 Review in New Phytologist New Phytol. 244, 786-797 (2024)
Interorgan, intraorgan and interplant communication mediated by nitric oxide and related species.
2024 Scientific Article in Cancers Cancers 16:2885 (2024)
Perioperative predictive factors for tumor regression and survival in non-Small cell lung cancer patients undergoing neoadjuvant treatment and lung resection.
2024 Scientific Article in Advanced science Adv. Sci.:e2404661 (2024)
The eATP/P2×7R axis drives quantum dot-nanoparticle induced neutrophil recruitment in the pulmonary microcirculation.
2024 Scientific Article in European Radiology Eur. Radiol., DOI: 10.1007/s00330-024-11031-9 (2024)
Preserved prenatal lung growth assessed by fetal MRI in the omicron-dominated phase of the SARS-CoV-2 pandemic.
2024 Scientific Article in Translational Oncology Transl. Oncol. 49:102070 (2024)
Improved survival of patients with stage III small-cell lung cancer with primary resection: A SEER-based analysis.
2024 Scientific Article in European Respiratory Journal Eur. Respir. J. 64, DOI: 10.1183/13993003.02071-2023 (2024)
Airway derived emphysema-specific alveolar type II cells exhibit impaired regenerative potential in COPD.
2024 Scientific Article in Frontiers in Cellular and Infection Microbiology Front. Cell. Infect. Microbiol. 14:1383917 (2024)
Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication.
2024 Review in American Journal of Transplantation Am. J. Transplant., DOI: 10.1016/j.ajt.2024.07.033 (2024)
Murine orthotopic lung transplant models: A comprehensive overview of genetic mismatch degrees and histopathological insights into chronic lung allograft dysfunction.
2024 Scientific Article in Nano Today Nano Today 58:19 (2024)
Transdermal microneedles integrating biomimetic self-adjuvant particles for enhanced immunity.
2024 Scientific Article in NanoImpact NanoImpact 35:100523 (2024)
Next generation risk assessment approaches for advanced nanomaterials: current status and future perspectives.
2024 Scientific Article in Cells Cells 13:1129 (2024)
Stimuli-specific senescence of primary human lung fibroblasts modulates alveolar stem cell function.
In: Progress and Prospect of Nanocarriers: Design, Concept, and Recent Advances. 2024. 289-326
Polymeric micelles for drug delivery: Properties, designs and applications.
2024 Scientific Article in Molecular Carcinogenesis Mol. Carcinog. 63, 1024-1037 (2024)
Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer.
2024 Scientific Article in Gut (eGut) Gut, DOI: 10.1136/gutjnl-2023-331519 (2024)
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2.
2024 Scientific Article in Apoptosis Apoptosis 29, 1145-1160 (2024)
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP.
2024 Scientific Article in Frontiers in Immunology Front. Immunol. 15:1425938 (2024)
Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction.
2024 Scientific Article in Cell Death Discovery Cell Death Discov. 10:311 (2024)
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung.
2024 Scientific Article in International Journal of Chronic Obstructive Pulmonary Disease Int. J. Chron. Obstruct. Pulmon. Dis. 19, 1515-1529 (2024)
Expiratory venous volume and arterial tortuosity are associated with disease severity and mortality risk in patients with COPD: Results from COSYCONET.
2024 Review in Journal of Clinical Medicine J. Clin. Med. 13:3977 (2024)
Revolutionizing gastrointestinal disorder management: Cutting-edge advances and future prospects.
Methods in Molecular Biology In: RNA Amplification and Analysis. 2024. 187-203 (Methods Mol. Biol. ; 2822)
Fluorescent Techniques for RNA Detection in Nanoparticles.
2024 Scientific Article in Genome Biology Genome Biol. 25:181 (2024)
Panpipes: A pipeline for multiomic single-cell and spatial transcriptomic data analysis.
2024 Review in Biomedicine & pharmacotherapy BIOMED. PHARMACOTHER. 177:117001 (2024)
Advances in biomedical applications of vitamin D for VDR targeted management of obesity and cancer.
2024 Scientific Article in Genome Biology Genome Biol. 25:109 (2024)
hadge: A comprehensive pipeline for donor deconvolution in single-cell studies.
2024 Scientific Article in World Journal of Diabetes World J. Diabetes 15, 1045-1047 (2024)
Tailored nutritional interventions: A precision approach to managing gestational diabetes mellitus.
2024 Review in Redox Biology Redox Biol. 75:103211 (2024)
Ferroptosis in health and disease.
2024 Review in Biomedicine & pharmacotherapy BIOMED. PHARMACOTHER. 176:116849 (2024)
Impacts of oxidative stress and anti-oxidants on the development, pathogenesis, and therapy of sickle cell disease: A comprehensive review.
2024 Scientific Article in Environmental Science: Nano Environ. Sci.-Nano, DOI: 10.1039/d3en00831b (2024)
Advanced materials earliest assessment (AMEA).
2024 Scientific Article in Journal of extracellular vesicles J. Extra. Vesicles 13:e12447 (2024)
Lipid A in outer membrane vesicles shields bacteria from polymyxins.
2024 Review in Diseases Diseases 12:93 (2024)
Unravelling the triad of lung cancer, drug resistance, and metabolic pathways.
2024 Scientific Article in Cytometry Part A Cytometry A, DOI: 10.1002/cyto.a.24843 (2024)
Impact of different tissue dissociation protocols on endothelial cell recovery from developing mouse lungs.
2024 Scientific Article in BMC Pediatrics BMC Pediatr. 24:249 (2024)
Delineating morbidity patterns in preterm infants at near-term age using a data-driven approach.
2024 Scientific Article in Nature Communications Nat. Commun. 15:1960 (2024)
Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization.
2024 Scientific Article in Journal of the World Federation of Orthodontists J. World Fed. Orthod., DOI: 10.1016/j.ejwf.2024.01.002 (2024)
Increased susceptibility for nonsyndromic cleft lip with or without cleft palate by SLC19A1 80G>A genetic variation.
2024 Scientific Article in EBioMedicine EBioMedicine 101:105030 (2024)
Ventilatory capacity in CLAD is driven by dysfunctional airway structure.
2024 Review in Current Treatment Options in Oncology Curr. Treat. Options Oncol. 25, 465-495 (2024)
A comprehensive review of cancer drug-induced cardiotoxicity in blood cancer patients: Current perspectives and therapeutic strategies.
2024 Scientific Article in Nature Methods Nat. Methods 21, 365-367 (2024)
OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data.
2024 Scientific Article in Cells Cells 13:241 (2024)
The immunopathology of pulmonary rejection after murine lung transplantation.
2024 Scientific Article in Thorax Thorax 79, 524-537 (2024)
COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors.
2024 Scientific Article in Environmental Science: Nano Environ. Sci.-Nano 11, 924-941 (2024)
Similarity of multicomponent nanomaterials in a safer-by-design context: The case of core-shell quantum dots.
2024 Review in Advanced science Adv. Sci. 11:e2308659 (2024)
Bridging smart nanosystems with clinically relevant models and advanced imaging for precision drug delivery.
2024 Nature Nature 625:E4 (2024)
Author Correction: CD201+ fascia progenitors choreograph injury repair.
2024 Scientific Article in European Respiratory Journal Eur. Respir. J. 63:2301326 (2024)
Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts.
Handbook of Experimental Pharmacology In:. 2024. DOI: 10.1007/164_2023_703 (Handb. Exp. Pharmacol.)
Targeted molecular therapeutics for pulmonary diseases: Addressing the need for precise drug delivery.
2024 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 209, 427-443 (2024)
Inhalable textile microplastic fibers impair airway epithelial differentiation.
In: Multifunctional And Targeted Theranostic Nanomedicines: Formulation, Design And Applications. 2023. 187-213
Functionalized carbon nanotubes, graphene oxide, fullerenes, and nanodiamonds: Emerging theranostic nanomedicines.
2023 Scientific Article in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 42, 102-114 (2023)
Risk stratification and response to therapy in patients with pulmonary arterial hypertension and comorbidities: A COMPERA analysis.
In: (Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference). 2023. 1-5 ( ; 2023)
Colorimetric Sensor Reading and Illumination Correction via Multi-Task Deep-Learning.
2023 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 207, 283-299 (2023)
Notch1 induces defective epithelial surfactant processing and pulmonary fibrosis.
2023 Review in World Journal of Virology World J. Virol. 12, 242-255 (2023)
Emerging perspectives on RNA virus-mediated infections: From pathogenesis to therapeutic interventions.
2023 Meeting abstract in European Respiratory Journal Eur. Respir. J. 62:2 (2023)
Evolution of epithelial-mesenchymal cell circuits in the progression of pulmonary fibrosis.
2023 Meeting abstract in European Respiratory Journal Eur. Respir. J. 62:3 (2023)
A spatially resolved extracellular matrix proteome atlas of the distal human lung.
2023 Scientific Article in Pulmonary Circulation Pulm. Circ. 13:e12320 (2023)
Current diagnosis and treatment practice for pulmonary hypertension in bronchopulmonary dysplasia-A survey study in Germany (PUsH BPD).
2023 Scientific Article in Cells Cells 12:22 (2023)
A mouse model to study the pathogenesis of γ-herpesviral infections in germinal center B cells.
2023 Scientific Article in Radiology. Artificial intelligence Radiol. Artif. Intell. 5:e220239 (2023)
Automated MRI lung segmentation and 3D morphologic features for quantification of neonatal lung disease.
2023 Letter to the Editor in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 70, 155-156 (2023)
A NEAT discovery hints at altered golgi signaling in lung fibrosis.
2023 Scientific Article in Science Translational Medicine Sci. Transl. Med. 15, 19:eadh0908 (2023)
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis.
2023 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 209, 683-692 (2023)
Small airways disease in Pre-COPD with emphysema: A cross-sectional study.
2023 Review in Current Oncology Curr. Oncol. 30, 9542-9568 (2023)
Unveiling therapeutic targets for esophageal cancer: A comprehensive review.
2023 Scientific Article in Science Advances Sci. Adv. 9:eadj3793 (2023)
Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus.
In: Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges. 2023. 103-134
Hormonal delivery systems.
2023 Scientific Article in BioSpektrum BioSpektrum 29, 755-757 (2023)
Bioinspirierte Lunge–auf–Chip als Alternative zu Tierversuchen.
2023 Review in Turkish Journal of Immunology Turk. J. Immunol. 11, 1-16 (2023)
Advances in the molecular etiology of severe combined immunodeficiency and its screening.
2023 Scientific Article in OpenNano OpenNano 12:100161 (2023)
Lab-scale siRNA and mRNA LNP manufacturing by various microfluidic mixing techniques – an evaluation of particle properties and efficiency.
2023 Review in Atemwegs- und Lungenkrankheiten Atemwegs- Lungenkr. 49, 140-146 (2023)
Aging and regeneration in the lung – Significance for COPD.
2023 Scientific Article in Environment International Environ. Int. 179:108169 (2023)
Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents.
2023 Scientific Article in European Respiratory Journal Eur. Respir. J. 62:14 (2023)
MRI pulmonary artery flow detects lung vascular pathology in preterms with lung disease.
2023 Scientific Article in American Journal of Pathology, The Am. J. Pathol. 193, 2001-2016 (2023)
Granulocyte colony-stimulating factor is a determinant of severe bronchopulmonary dysplasia and coincident retinopathy.
2023 Scientific Article in European Respiratory Journal Eur. Respir. J. 62:14 (2023)
The impact of the immune system on lung injury and regeneration in COPD.
2023 Scientific Article in Nanomedicine Nanomed. 18, 1261-1279 (2023)
Multifunctional nanotherapeutics for intracellular trafficking of doxorubicin against breast cancer.
2023 Scientific Article in Translational Oncology Transl. Oncol. 39:101800 (2023)
Clinical identification of malignant pleural effusions.
2023 Editorial in Alternatives to Animal Experimentation : ALTEX ALTEX 40, 689-693 (2023)
Report of the 3rd and 4th Mystery of Reactive Oxygen Species Conference.
2023 Scientific Article in iScience iScience 26:108345 (2023)
Mass spectrometry-based autoimmune profiling reveals predictive autoantigens in idiopathic pulmonary fibrosis.
2023 Scientific Article in Nature Nature 623, 792-802 (2023)
CD201+ fascia progenitors choreograph injury repair.
2023 Scientific Article in European Respiratory Journal Eur. Respir. J. 63:2300127 (2023)
Mortality surrogates in combined pulmonary fibrosis and emphysema.
2023 Scientific Article in EBioMedicine EBioMedicine 98:104869 (2023)
ACE2-independent SARS-CoV-2 virus entry through cell surface GRP78 on monocytes - evidence from a translational clinical and experimental approach.
2023 Scientific Article in Frontiers in Medicine Front. Med. 10:1118715 (2023)
The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD.
2023 Editorial in Cell Stem Cell Cell Stem Cell 30, 1397-1399 (2023)
Multilineage circuits of regenerative cell states.
2023 Scientific Article in ACS Nano ACS Nano 17, 21056-21072 (2023)
Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice.
2023 Scientific Article in Journal of Drug Delivery Science and Technology J. Drug Deli. Sci. Technol. 82:104316 (2023)
Breathing-induced stretch enhances the efficacy of an inhaled and orally delivered anti-fibrosis drug in vitro.
2023 Scientific Article in Experimental Hematology and Oncology Exp. Hematol. Oncol. 12:80 (2023)
Recent advances and future perspectives in the therapeutics of prostate cancer.
2023 Editorial in Signal transduction and targeted therapy Signal Transduct. Target. Ther. 8:332 (2023)
Fumarate hydratase: A new checkpoint of metabolic regulation in inflammatory macrophages.
2023 Scientific Article in Frontiers in Microbiology Front. Microbiol. 14:1072053 (2023)
Physiological changes during torpor favor association with Endozoicomonas endosymbionts in the urochordate Botrylloides leachii.
2023 Scientific Article in Frontiers in Plant Science Front. Plant Sci. 14:1124899 (2023)
Arabidopsis histone deacetylase HD2A and HD2B regulate seed dormancy by repressing DELAY OF GERMINATION 1.
2023 Scientific Article in European Respiratory Journal Eur. Respir. J. 62:16 (2023)
Antiviral CD8+T-cell immune responses are impaired by cigarette smoke and in COPD.
2023 Scientific Article in Nature Methods Nat. Methods 20, 1530-1536 (2023)
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome.
2023 Scientific Article in Mathematical Biosciences Math. Biosci. 365:109076 (2023)
Age structure, replicator equation, and the prisoner's dilemma.
2023 Scientific Article in Biomolecules Biomolecules 13:18 (2023)
A lysine residue at the C-terminus of MHC class I ligands correlates with low C-terminal proteasomal cleavage probability.
2023 Scientific Article in Genes Genes 14:27 (2023)
Histone deacetylases HD2A and HD2B undergo feedback regulation by ABA and modulate drought tolerance via mediating ABA-induced transcriptional repression.
2023 Scientific Article in Advances in Experimental Medicine and Biology Adv. Exp. Med. Biol. 1413, 213-244 (2023)
Assessment of collagen in translational models of lung research.
2023 Review in Nature Biotechnology Nat. Biotechnol. 41, 604-606 (2023)
The scverse project provides a computational ecosystem for single-cell omics data analysis.
2023 Scientific Article in Cancers Cancers 15:23 (2023)
Non-oncogene addiction of KRAS-mutant cancers to IL-1β via versican and mononuclear IKKβ.
2023 Scientific Article in Frontiers in Immunology Front. Immunol. 14:1112608 (2023)
Monocyte signature as a predictor of chronic lung disease in the preterm infant.
ERJ Open Research In:. 442 Glossop Rd, Sheffield S10 2px, England: European Respiratory Soc Journals Ltd, 2023.:12 (ERJ Open Res. ; 9)
ERS International Congress 2022: Highlights from the Basic and Translational Science Assembly.
2023 Scientific Article in Science Advances Sci. Adv. 9:eadd8564 (2023)
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy.
2023 Scientific Article in EMBO Journal, The EMBO J. 42:e110597 (2023)
DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity.
2023 Editorial in European Respiratory Journal Eur. Respir. J. 61:3 (2023)
Another piece in the pirfenidone puzzle.
2023 Frontiers in Immunology Front. Immunol. 14:1209992 (2023)
Corrigendum: Monocyte signature as a predictor of chronic lung disease in the preterm infant.
2023 Review in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 396, 2287-2310 (2023)
Advancement in nanotechnology for treatment of rheumatoid arthritis: Scope and potential applications.
2023 Scientific Article in NanoImpact NanoImpact 31:100466 (2023)
Transferability and reproducibility of exposed air-liquid interface co-culture lung models.
2023 Scientific Article in Frontiers in Immunology Front. Immunol. 14:1128239 (2023)
Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures.
2023 Scientific Article in Nature Cancer Nat. Cancer 4, 629-647 (2023)
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.
2023 Scientific Article in Antioxidants Antioxidants 12:16 (2023)
L-aminoguanidine induces imbalance of ROS/RNS homeostasis and polyamine catabolism of tomato roots after short-term salt exposure.
2023 Scientific Article in Nature Communications Nat. Commun. 14:4564 (2023)
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.
2023 Scientific Article in Pharmaceuticals Pharmaceuticals 16:20 (2023)
Numerical and experimental analysis of drug inhalation in realistic human upper airway model.
2023 Scientific Article in Bioinformatics Bioinformatics 39:8 (2023)
mlf-core: A framework for deterministic machine learning.
2023 Scientific Article in Nature Reviews - Genetics Nat. Rev. Genet. 24, 550-572 (2023)
Best practices for single-cell analysis across modalities.
2023 Scientific Article in Nature medicine Nat. Med. 29, 1563-1577 (2023)
An integrated cell atlas of the lung in health and disease.
2023 Editorial in Frontiers in Toxicology Front. Toxicology 5:1148374 (2023)
Editorial: Exploring impacts of combined exposures to particles and chemicals on immune reactions across living organisms.
2023 Scientific Article in Diagnostics Diagnostics 13:14 (2023)
Histology of the primary tumor correlates with false positivity of integrated 18F-FDG-PET/CT lymph node staging in resectable lung cancer patients.
2023 Scientific Article in Cell Reports Cell Rep. 42:112533 (2023)
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer.
2023 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 325, L95-L103 (2023)
Prenatal vitamin D supplementation mitigates inflammation-related alveolar remodeling in neonatal mice.
2023 Scientific Article in Cell Reports Cell Rep. 42:112525 (2023)
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.
2023 Scientific Article in Nature Communications Nat. Commun. 14:3020 (2023)
Wound infiltrating adipocytes are not myofibroblasts.
2023 Scientific Article in Chest Chest 164, 1476-1480 (2023)
Intrafamilial correlation and variability in the clinical evolution of pulmonary fibrosis.
2023 Review in Journal of Investigative Dermatology, The J. Invest. Dermatol. 143, 1667-1677 (2023)
A Roadmap for a consensus human skin cell atlas and single-cell data standardization.
2023 Scientific Article in BMC Public Health BMC Public Health 23:416 (2023)
High variability of COVID-19 case fatality rate in Germany.
2023 Editorial in European Respiratory Journal Eur. Respir. J. 61:2202417 (2023)
Oxysterol metabolism dictates macrophage influx during SARS-CoV-2 infection.
2023 Scientific Article in BMC Surgery BMC Surg. 23:44 (2023)
Preoperative risk factors predict perioperative allogenic blood transfusion in patients undergoing primary lung cancer resections: a retrospective cohort study from a high-volume thoracic surgery center.
2023 Review in Advanced materials Adv. Mater. 35:e2210519 (2023)
Biomimetic in vitro lung models: Current challenges and future perspective.
2023 Scientific Article in Frontiers in Microbiology Front. Microbiol. 13:957830 (2023)
Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection.
2023 Scientific Article in Pharmaceuticals Pharmaceuticals 16:14 (2023)
Numerical and machine Learning analysis of the parameters affecting the regionally delivered nasal dose of nano- and micro-sized aerosolized drugs.
2023 Scientific Article in Journal of Controlled Release J. Control. Release 354, 305-315 (2023)
Targeted GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma.
2023 Scientific Article in Pediatric Research Pediatr. Res. 93, 625-632 (2023)
Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia.
2022 Scientific Article in IEEE Xplore IEEE Xplore, 28-33 (2022)
Evaluating the Potential of Ellipsoidal Particles for Inhalation Therapy in Comparison to Spherical Particles.
2022 Scientific Article in European Respiratory Journal Eur. Respir. J. 61:2201506 (2022)
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.
2022 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:15666 (2022)
Lung organoids for hazard assessment of nanomaterials.
2022 Scientific Article in Sarcoidosis Vasculitis and Diffuse Lung Diseases Sarcoidosis Vasc. Diffus. Lung Dis. 39:e2022016 (2022)
Bronchoscopic probe-based confocal laser endomicroscopy to diagnose diffuse parenchymal lung diseases.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:21028 (2022)
Exome variants associated with asthma and allergy.
2022 Scientific Article in Frontiers in Medicine Front. Med. 9:988927 (2022)
Transferability of radiomic signatures from experimental to human interstitial lung disease.
2022 Scientific Article in Pneumologie Pneumologie, DOI: 10.1055/a-1956-8800 (2022)
Impact of short-term pausing of oral corticosteroids on blood eosinophil count in patients with severe asthma.
2022 Scientific Article in Respiratory physiology & neurobiology Respir. Physiol. Neurobiol. 308:103986 (2022)
Targeted drug delivery with polydisperse particle transport and deposition in patient-specific upper airway during inhalation and exhalation.
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Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
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Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung (Nature, (2020), 588, 7836, (151-156), 10.1038/s41586-020-2882-8).
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Connexin43 gap junction drives fascia mobilization and repair of deep skin wounds.
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2021 Letter to the Editor in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 64, 271-272 (2021)
Scientific integrity is threatened by image duplications.
2021 Scientific Article in Journal of Proteome Research J. Proteome Res. 20, 751-762 (2021)
Multiplatform approach for plasma proteomics: Complementarity of olink proximity extension assay technology to mass spectrometry-based protein profiling.
2021 Scientific Article in Chem Chem 7, 480-494 (2021)
Synergistic combination of calcium and citrate in mesoporous nanoparticles targets pleural tumors.
2021 Scientific Article in Advanced materials Adv. Mater. 33:2005476 (2021)
Extracellular-matrix-reinforced bioinks for 3D bioprinting human tissue.
2021 Scientific Article in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 146, E1-E9 (2021)
Die frühe Phase der COVID-19-Pandemie in Bayern.
2021 Scientific Article in Biotechnology and Bioengineering Biotechnol. Bioeng. 118, 690-702 (2021)
Development of a dynamic in vitro stretch model of the alveolar interface with aerosol delivery.
2021 Scientific Article in Lancet Respiratory Medicine, The Lancet Resp. Med. 9, 85-95 (2021)
Efficacy and safety of sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A double-blind, randomised, placebo-controlled, phase 2b trial.
2021 Scientific Article in The journal of allergy and clinical immunology J. Allergy Clin. Immunol. 147, 1041-1048 (2021)
Human milk oligosaccharide profiles and allergic disease up to 18 years.
2020 Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 146, e1-e9 (2020)
Erratum: Die frühe Phase der COVID-19-Pandemie in Bayern.
2020 Scientific Article in European Respiratory Journal Eur. Respir. J. 56:2001400 (2020)
Socioeconomic correlates of SARS-CoV-2 and influenza H1N1 outbreaks.
2020 Other: Opinion in Immunity, Inflammation and Disease Immun. Inflamm. Dis. 9, 74-75 (2020)
Allergy protection at farms-just a myth?
2020 Review in ERJ Open Research ERJ Open Res. 6:00350-2019 (2020)
ERS International Congress, Madrid, 2019: Highlights from the basic and translational science assembly.
2020 Scientific Article in Advanced Therapeutics Adv. Therap. 3:2000017 (2020)
Organ‐restricted vascular delivery of nanoparticles for lung cancer therapy.
2020 Scientific Article in Frontiers in Medicine Front. Med. 7:606330 (2020)
Senescent cells in IPF: Locked in repair?
2020 Scientific Article in Advanced functional materials Adv. Func. Mat., DOI: 10.1002/adfm.202004707 (2020)
A biomimetic, copolymeric membrane for cell-stretch experiments with pulmonary epithelial cells at the air-liquid interface.
2020 Scientific Article in Frontiers in Medicine Front. Med. 7:601279 (2020)
Idiopathic pulmonary fibrosis in elderly patients: Analysis of the INSIGHTS-IPF Observational Study.
2020 Scientific Article in European Respiratory Journal Eur. Respir. J. 57, DOI: 10.1183/13993003.01416-2020 (2020)
Cathepsin B promotes collagen biosynthesis driving Bronchiolitis Obliterans Syndrome.
2020 Scientific Article in Annals of Thoracic Surgery Ann. Thorac. Surg. 110, e461-e463 (2020)
Clinical course of three postoperative symptomatic COVID-19 cases in patients after lung lobectomy.
2020 Scientific Article in International Journal of Chronic Obstructive Pulmonary Disease Int. J. Chron. Obstruct. Pulmon. Dis. 15, 2787-2798 (2020)
Impact of education on COPD severity and all-cause mortality in lifetime never-smokers and longtime ex-smokers: Results of the COSYCONET cohort.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:18444 (2020)
A proof-of principal study using phase-contrast imaging for the detection of large airway pathologies after lung transplantation.
2020 Scientific Article in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 39, 1435-1444 (2020)
Idiopathic pulmonary arterial hypertension phenotypes determined by cluster analysis from the COMPERA registry.
2020 Scientific Article in European Respiratory Review Eur. Respir. Rev. 29:200222 (2020)
Lung regeneration: Implications of the diseased niche and ageing.
2020 Scientific Article in Respiratory Research Respir. Res. 21:270 (2020)
Variability of forced vital capacity in progressive interstitial lung disease: A prospective observational study.
2020 Scientific Article in Nature Communications Nat. Commun. 11:5653 (2020)
Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin.
2020 Scientific Article in Nature Nature 588, 151–156 (2020)
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
2020 Scientific Article in Respiratory Medicine Respir. Med. 175:106194 (2020)
Effect of BMI on health care expenditures stratified by COPD GOLD severity grades: Results from the LQ-DMP study.
2020 Scientific Article in Thorax Thorax 75, 1004-1008 (2020)
Patient-derived malignant pleural mesothelioma cell cultures: A tool to advance biomarker-driven treatments.
2020 Scientific Article in Physics of Fluids Phys. Fluids 32:101905 (2020)
Large eddy simulations of airflow and particle deposition in pulsating bi-directional nasal drug delivery.
2020 Scientific Article in Advanced healthcare materials Adv. Healthc. Mater. 9:2000918 (2020)
Precision 3D-printed cell scaffolds mimicking native tissue composition and mechanics.
2020 Scientific Article in JCI insight JCI insight 5:e134464 (2020)
TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema.
2020 Scientific Article in Health and Quality of Life Outcomes Health Qual. Life Outcomes 18:334 (2020)
Determinants of health-related quality of life decline in interstitial lung disease.
2020 Scientific Article in Advanced materials Adv. Mater. 32:e2003913 (2020)
Prediction of chronic inflammation for inhaled particles: The impact of material cycling and quarantining in the lung epithelium.
2020 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 17:44 (2020)
Quartz crystal microbalances (QCM) are suitable for real-time dosimetry in nanotoxicological studies using VITROCELL®Cloud cell exposure systems.
2020 Scientific Article in The journal of allergy and clinical immunology. In practice J. Allergy Clin. Immunol. Pract. 9, 1177-1185.e4 (2020)
Dupilumab improves asthma control and lung function in patients with insufficient outcome during previous antibody therapy.
2020 Scientific Article in European Respiratory Journal Eur. Respir. J. 56:1902279 (2020)
Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: Long-term results of the INSIGHTS-IPF registry.
2020 Scientific Article in Nature Communications Nat. Commun. 11:4527 (2020)
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.
2020 Review in Radiation Oncology Radiat. Oncol. 15:214 (2020)
Radiation-induced lung toxicity - cellular and molecular mechanisms of pathogenesis, management, and literature review.
2020 Scientific Article in Journal of Proteome Research J. Proteome Res. 19, 2950-2963 (2020)
Proteomics analysis revealed the importance of inflammation mediated downstream pathways and the protective role of curcumin during bleomycin-induced pulmonary fibrosis in C57BL/6 mice.
2020 Scientific Article in Respiratory Medicine Respir. Med. 172:106117 (2020)
Relationship between clinical and radiological signs of bronchiectasis in COPD patients: Results from COSYCONET.
2020 Review in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 8:697 (2020)
Mesenchymal stem cells adaptively respond to environmental cues thereby improving granulation tissue formation and wound healing.
2020 Review in European Respiratory Review Eur. Respir. Rev. 29:200126 (2020)
The ageing lung under stress.
2020 Scientific Article in Computers in Biology and Medicine Comput. Biol. Med. 123:103816 (2020)
Simulation of patient-specific bi-directional pulsating nasal aerosol dispersion and deposition with clockwise 45 degrees and 90 degrees nosepieces.
2020 Scientific Article in Nature Communications Nat. Commun. 11:3559 (2020)
Alveolar regeneration through a Krt8+transitional stem cell state that persists in human lung fibrosis.
München, Ludwig Maximilian Universität, Medizinische Fakultät, Diss., 2020, 144 S.
An in vivo inflammatory loop potentiates KRAS blockade.
2020 Scientific Article in Cell Reports Cell Rep. 32:108059 (2020)
Mitochondrial regulation of the 26S proteasome.
2020 Letter to the Editor in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 117, 287-287 (2020)
Environmental science or environmental activism?
2020 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 9:1567 (2020)
Short-term effects of comprehensive pulmonary rehabilitation and its maintenance in patients with idiopathic pulmonary fibrosis: A randomized controlled trial.
2020 Scientific Article in Science Advances Sci. Adv. 6:eaaz6105 (2020)
Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer.
2020 Scientific Article in Journal of Molecular Histology J. Mol. Histol. 51, 385-400 (2020)
Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival.
2020 Scientific Article in Nature Communications Nat. Commun. 11:3068 (2020)
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.
2020 Review in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 62, 681-691 (2020)
Applications and approaches for three-dimensional precision-cut lung slices disease modeling and drug discovery.
2020 Scientific Article in BMC Pulmonary Medicine BMC Pulm. Med. 20:168 (2020)
How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire?
2020 Scientific Article in Stem Cells Stem Cells 38, 1467-1478 (2020)
Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema.
2020 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 17:21 (2020)
Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm silver nanoparticle aerosols in healthy adult rats after a single 11/2-hour inhalation exposure.
2020 Review in Particle and Fibre Toxicology Part. Fibre Toxicol. 17:16 (2020)
Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale.
2020 Review in Advances in Experimental Medicine and Biology Adv. Exp. Med. Biol. 1233, 55-100 (2020)
The proteasome system in health and disease.
2020 Scientific Article in EMBO Reports EMBO Rep. 21:e48777 (2020)
TLR4-dependent shaping of the wound site by MSCs accelerates wound healing.
2020 Review in Pharmacology & Therapeutics. Pharmacol. Ther. 211:107526 (2020)
Exploring the proteasome system: A novel concept of proteasome inhibition and regulation.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0232847 (2020)
Automated evaluation of probe-based confocal laser endomicroscopy in the lung.
2020 Review in Cell Proliferation Cell Prolif. 53:e12828 (2020)
Role of exosomal microRNAs in lung cancer biology and clinical applications.
2020 Scientific Article in Allergy Allergy 75, 1979-1990 (2020)
Antibiotic use during pregnancy increases offspring asthma severity in a dose-dependent manner.
2020 Scientific Article in Frontiers in Cardiovascular Medicine Front. Cardiovasc. Med. 7:51 (2020)
Comparison of MRI and VQ-SPECT as a screening test for patients with suspected CTEPH: CHANGE-MRI study design and rationale.
2020 Scientific Article in BMC Biology BMC Biol. 18:42 (2020)
Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation.
2020 Scientific Article in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 39, S22 (2020)
Rapid activation of pro-lymphangiogenic phenotype and consequent increase of lymphatic density occurs during the development of chronic lung allograft dysfunction.
2020 Meeting abstract in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 39, S356-S357 (2020)
Regulation of cysteine-protease activity prevents graft dysfunction during ischemia-lung reperfusion.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A16-A16 (2020)
Scar formation is driven by N-cadherin dependent collective fibroblast migration.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A6-A6 (2020)
Subcutaneous fascia is a cell repository for scars.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A10-A10 (2020)
Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A1-A1 (2020)
HIPSC in vitro model for therapeutic strategies in fibrotic regeneration.
2020 Review in Biochemical Society Transactions Biochem. Soc. Trans. 48, 231-243 (2020)
Noncanonical Wnt planar cell polarity signaling in lung development and disease.
2020 Scientific Article in Cellular Signalling Cell. Signal. 70:109588 (2020)
Chronic WNT/β-catenin signaling induces cellular senescence in lung epithelial cells.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A6-A6 (2020)
Rebuilding new lungs: Studying homing of progenitor lung cell types into their native niche of decellularized ex vivo human lung slices by 4D live-cell light-sheet microscopy.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A15-A15 (2020)
Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A13-A13 (2020)
Regeneration of airway epithelial cell regulated by arginine methylation.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A7-A7 (2020)
Fate trajectory modeling reveals convergence of airway derived progenitors and AT2 cells on transient KRT8+alveolar cell state during lung regeneration.
2020 Scientific Article in Clinical & Experimental Allergy Clin. Exp. Allergy 50, 520-531 (2020)
Maternal asthma is associated with persistent changes in allergic offspring antibody glycosylation.
2020 Review in Expert Opinion on Drug Delivery Expert Opin. Drug Deliv. 17, 463-478 (2020)
Innovative preclinical models for pulmonary drug delivery research.
2020 Review in Small Small 16:1907476 (2020)
Acute phase response as a biological mechanism-of-action of (nano)particle-induced cardiovascular disease.
2020 Scientific Article in Mammalian Genome Mamm. Genome 31, 30-48 (2020)
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
2020 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:617 (2020)
Scars or regeneration?-Dermal fibroblasts as drivers of diverse skin in wound responses.
2020 Review in Expert Review of Pharmacoeconomics and Outcomes Research Expert Rev. Pharmacoecon. Outcomes Res. 20, 79-91 (2020)
Effectiveness of non-pharmacological COPD management on health-related quality of life-a systematic review.
2020 Meeting abstract in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 393, 37-37 (2020)
Essential functions of TRPV4 channels in alveolar epithelium.
Advances in Experimental Medicine and Biology In: Tumor Microenvironment. Gewerbestrasse 11, Cham, Ch-6330, Switzerland: Springer International Publishing Ag, 2020. 53-69 (Adv. Exp. Med. Biol. ; 1225)
Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment.
2020 Scientific Article in Environmental Toxicology and Pharmacology Environ. Toxicol. Pharmacol. 74:103303 (2020)
Pulmonary toxicity of Fe2O3, ZnFe2O4, NiFe2O4 and NiZnFe4O8 nanomaterials: Inflammation and DNA strand breaks.
2020 Scientific Article in Toxicology and Applied Pharmacology Toxicol. Appl. Pharmacol. 386:114830 (2020)
Effects of physicochemical properties of TiO2 nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally exposed mice.
2020 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 117, 1201-1206 (2020)
Variable functional connectivity architecture of the preterm human brain: Impact of developmental cortical expansion and maturation.
2020 Scientific Article in European Respiratory Journal Eur. Respir. J. 55:1900460 (2020)
CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases.
2020 Scientific Article in Wound repair and regeneration Wound Repair Regen. 28, 49-60 (2020)
Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing.
2020 Scientific Article in Allergy Allergy 75, 370-380 (2020)
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.
2020 Scientific Article in Cardiovascular Research Cardiovasc. Res. 116, 406-415 (2020)
Altered proteasome function in right ventricular hypertrophy.
2020 Scientific Article in Thorax Thorax 75, 184-187 (2020)
Altered relaxation times in MRI indicate bronchopulmonary dysplasia.
2019 Scientific Article in Padiatrische Praxis Padiat. Praxis 92, 604-611 (2019)
Neue diagnostische Werkzeuge für die frühzeitige Identifikation und strukturelle Charakterisierung der Bronchopulmonalen Dysplasie.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Prevotella genera abundance in bronchial brush samples differentiates COPD from health and is associated with gene expression.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Association between COPD bronchial brush microbiome-determined ?Proteobacteria:Firmicutes (G:F) ratio and GOLD grade and symptoms.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
LSC-2019-Relevant murine model to study the development of COPD pathogenesis in smokers with viral infections.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Hyperoxia exposure induces age-dependent changes in gene expression in healthy mouse lung.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Late Breaking Abstract - WNT/beta-catenin signaling induces cellular senescence in lung alveolar epithelial cells.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Expression profiling of genes differentially regulated under hyperoxia andmechanical ventilation in mouse model of neonatal chronic lung disease.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
LSC-2019-Validating immunoproteasome activity as a potential biomarker in non-invasive samples from COPD patients.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
LSC-2019-Effect of cigarette smoke on immunoproteasome function during virus infection.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Mitochondrial dysfunction activates MHC class I adaptive immune responses in lung aging.
2019 Meeting abstract in European Respiratory Journal Eur. Respir. J. 54 (2019)
Late Breaking Abstract - Survival and course of lung function in patients with idiopathic pulmonary fibrosis with or without antifibrotic treatment: Long-term results of the INSIGHTS-IPF registry.
2019 Scientific Article in Proceedings of SPIE Proc. SPIE 11113:111130G (2019)
In vivo x-ray imaging of the respiratory system using synchrotron sources and a compact light source.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:20158 (2019)
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.
2019 Scientific Article in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 61, 713-726 (2019)
The oncogene ECT2 contributes to a hyperplastic, proliferative lung epithelial cell phenotype in idiopathic pulmonary fibrosis.
2019 Scientific Article in Nature Nature 576, 287-292 (2019)
Patch repair of deep wounds by mobilized fascia.
2019 Scientific Article in Nature Nature 575, 693-698 (2019)
FSP1 is a glutathione-independent ferroptosis suppressor.
2019 Scientific Article in Thorax Thorax 75, 8-16 (2019)
Resistome analyses of sputum from COPD and healthy subjects reveals bacterial load-related prevalence of target genes.
2019 Scientific Article in Carcinogenesis Carcinogenesis 41, 1134-1144 (2019)
Osteopontin drives KRAS-mutant lung adenocarcinoma.
2019 Scientific Article in Frontiers in Pharmacology Front. Pharmacol. 10:1293 (2019)
Unpredictable nanoparticle retention in commonly used plastic syringes introduces dosage uncertainties that may compromise the accuracy of nanomedicine and nanotoxicology studies.
2019 Scientific Article in International journal of applied pharmaceutics Int. J. Appl. Pharm. 11, 24-30 (2019)
Mannosylated multiwalled carbon nanotubes assisted artesunate delivery for cerebral malaria.
2019 Scientific Article in FASEB Journal FASEB J. 33, 12392-12408 (2019)
Susceptibility of microtubule-associated protein 1 light chain 3 beta (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.
2019 Scientific Article in Frontiers in Immunology Front. Immunol. 10:2467 (2019)
Remote activation of a latent epitope in an autoantigen decoded with simulated B-factors.
2019 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 317, L602-L614 (2019)
CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis.
2019 Review in Nature reviews - Rheumatology Nat. Rev. Rheumatol. 15, 705-730 (2019)
Shared and distinct mechanisms of fibrosis.
2019 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 317, L625-L638 (2019)
Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 1594-1595 (2019)
Antibiotic use during pregnancy impacts neonatal microbiota composition and increases offspring asthma severity.
2019 Meeting abstract in Journal of thoracic oncology J. Thorac. Oncol. 14, S454-S454 (2019)
An in vivo inflammatory loop potentiates KRAS blockade.
2019 Meeting abstract in European Journal of Human Genetics Eur. J. Hum. Genet. 27, 470-471 (2019)
The role of Trp53 in chemical-induced lung adenocarcinoma.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:15224 (2019)
Proteasome activator PA200 regulates myofibroblast differentiation.
2019 Scientific Article in Small Small 15:1904112 (2019)
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.
2019 Scientific Article in Review of Scientific Instruments Rev. Sci. Instruments 90:103103 (2019)
Optimization of in vivo murine X-ray dark-field computed tomography.
2019 Scientific Article in Journal of Cellular and Molecular Medicine J. Cell. Mol. Med. 23, 7985-7998 (2019)
HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization.
2019 Scientific Article in Blood advances Blood Adv. 3, 2713-2721 (2019)
Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation.
2019 Scientific Article in Journal of Pharmacology and Experimental Therapeutics J. Pharmacol. Exp. Ther. 370, 772-785 (2019)
Cellular vesicles: New insights in engineering methods, interaction with cells and potential for brain targeting.
2019 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 20:4747 (2019)
Processing and maturation of cathepsin C zymogen: A biochemical and molecular modeling analysis.
2019 Scientific Article in Science Signaling Sci. Signal. 12:eaaw2300 (2019)
Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity.
2019 Meeting abstract in Rheumatology Rheumatology 58, 222 (2019)
Preferential binding to an unexpected epitope of a chimeric recombinant proteinase 3 variant by anti-neutrophil cytoplasmic antibodies.
2019 Review in Cells Cells 8:815 (2019)
Osteopontin as a link between inflammation and cancer: The thorax in the spotlight.
2019 Scientific Article in Viruses Viruses 11:646 (2019)
The emergence of avian orthoavulavirus 13 in wild migratory waterfowl in China revealed the existence of diversified trailer region sequences and HN gene lengths within this serotype.
2019 Scientific Article in ACS applied materials & interfaces ACS Appl. Mater. Interfaces 11, 27503-27511 (2019)
Facile surface modification method for synergistically enhancing the biocompatibility and bioactivity of poly(ether ether ketone) that induced osteodifferentiation.
2019 Review in ERJ Open Research ERJ Open Res. 5:00194-2018 (2019)
From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 "Basic and Translational Science.".
2019 Review in Advanced functional materials Adv. Func. Mat. 29:1903114 (2019)
Evolution of bioengineered lung models: Recent advances and challenges in tissue mimicry for studying the role of mechanical forces in cell biology.
2019 Scientific Article in Matrix biology plus Matrix biology plus 1, DOI: 10.1016/j.mbplus.2019.04.002:100005 (2019)
Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro model of lung fibrosis.
2019 Scientific Article in Zeitschrift für Geburtshilfe und Neonatologie Z. Geburtsh. u. Neonat. 223, 178-178 (2019)
Langzeitentwicklung von Kindern nach Extra Corporaler Membran Oxygenierung (ECMO).
2019 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 317, L14-L28 (2019)
TGF-beta activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.
2019 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 16:29 (2019)
Quantitative biokinetics over a 28day period of freshly generated, pristine, 20 nm titanium dioxide nanoparticle aerosols in healthy adult rats after a single two-hour inhalation exposure.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:9925 (2019)
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.
2019 Scientific Article in Frontiers in Immunology Front. Immunol. 10:1189 (2019)
The glycosylation site of myelin oligodendrocyte glycoprotein affects autoantibody recognition in a large proportion of patients.
2019 Scientific Article in Journal of Controlled Release J. Control. Release 307, 282-291 (2019)
Visualizing treatment delivery and deposition in mouse lungs using in vivo x-ray imaging.
2019 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 17:68 (2019)
Cholecystokinin type B receptor-mediated inhibition of A-type K+ channels enhances sensory neuronal excitability through the phosphatidylinositol 3-kinase and c-Src-dependent JNK pathway.
2019 Meeting abstract in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 32, A9-A9 (2019)
Numerical models of respiratory drug deposition and pharmacokinetics: Application to liposomal ciclosporin a (L-CSA).
2019 Meeting abstract in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 32, A4-A4 (2019)
Advanced in vitro and in silico models improve predictions of in vivo/clinical pharmacokinetics of nanocarrier-laden inhaled drugs.
2019 Meeting abstract in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 32, A12-A12 (2019)
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.
2019 Scientific Article in Journal of thoracic disease J. Thorac. Dis. 11, 1963-1972 (2019)
Pleurectomy/decortication and hyperthermic intrathoracic chemoperfusion using cisplatin and doxorubicin for malignant pleural mesothelioma.
2019 Meeting abstract in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 32, A7-A7 (2019)
Towards prediction of the pharmacokinetics of inhaled nanomedicine from physiological cell models: A case study with liposomal ciclosporin A (L-CSA) using the vitrocell cloud system.
2019 Scientific Article in International Journal of Nanomedicine Int. J. Nanomed. 14, 3773-3784 (2019)
Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection.
2019 Scientific Article in ERJ Open Research ERJ Open Res. 5:00226-2018 (2019)
Novel mouse model of indwelling pleural catheter in mice with malignant pleural effusion.
2019 Scientific Article in eLife eLife 8:e45571 (2019)
Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Arginine methylation epigenetically regulates airway epithelial cell injury in COPD pathogenesis.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Developing oxysterol inhibitors as a novel therapeutic target for iBALT driven chronic pulmonary diseases.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Metabolomic regulation of B cells drives the pathogenesis of COPD.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Quantitative proteomic profiling of extracellular matrix and collagen posttranslational modifications in an in vitro model of lung fibrosis.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Epithelial cell transforming sequence 2 contributes to alveolar epithelial cell reprogramming in idiopathic pulmonary fibrosis.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Myeloid-derived suppressor cells orchestrate immunosuppressive networks in idiopathic pulmonary fibrosis.
2019 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 199 (2019)
Wnt1-inducible signaling protein 1 (WISP1) augments nuclear factor (NF)-kB signaling in primary human lung fibroblasts.
In: (Trans. Annu. Meet. Soc. Biomater. Annu. Int. Biomater. Symp., 03-06 April 2019, Seattle, USA). 2019. 560 ( ; 40)
Fine-tuning lung cancer nanotherapy using closed cardiopulmonary circulation.
2019 Scientific Article in NanoImpact NanoImpact 14:100158 (2019)
Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses.
2019 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 200, 199-208 (2019)
Resequencing study confirms host defense and cell senescence gene variants contribute to the risk of idiopathic pulmonary fibrosis.
2019 Scientific Article in EBioMedicine EBioMedicine 43, 562-575 (2019)
The Notch ligand DNER regulates macrophage IFN gamma release in chronic obstructive pulmonary disease.
2019 Scientific Article in Molecular Cell Mol. Cell 74, 951-965.e13 (2019)
Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition.
2019 Scientific Article in Annals of Internal Medicine Ann. Intern. Med. 170, 332-335 (2019)
Are requirements to deposit data in research repositories compatible with the european union's general data protection regulation?
2019 Scientific Article in OncoImmunology OncoImmunology 8:1593802 (2019)
Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma.
2019 Editorial in Allergy Allergy 74, 2052-2053 (2019)
We are still confused but on a higher level.
2019 Scientific Article in Experimental Eye Research Exp. Eye Res. 188:107632 (2019)
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
2019 Scientific Article in Nature Communications Nat. Commun. 10:1405 (2019)
Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma.
2019 Meeting abstract in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 38, S250-S250 (2019)
Elevetad cysteine-protease activity in bronchiolitis obliterans syndrome.
2019 Meeting abstract in Experimental Dermatology Exp. Dermatol. 28, E13-E13 (2019)
Visualizing scar development in living tissues reveals the collective migration of fibroblasts mediated by N-cadherin.
2019 Scientific Article in Carcinogenesis Carcinogenesis 40, 1240-1250 (2019)
Risk of lung adenocarcinoma from smoking and radiation arises in distinct molecular pathways.
2019 Scientific Article in Journal of Visualized Experiments J. Vis. Exp.:e58437 (2019)
Generation of human 3D lung tissue cultures (3D-LTCs) for disease modeling.
2019 Scientific Article in Carcinogenesis Carcinogenesis 40, 1352-1362 (2019)
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.
2019 Scientific Article in Journal of Immunology J. Immunol. 202, 1406-1416 (2019)
ARTD1 in myeloid cells controls the IL-12/18-IFN-γ axis in a model of sterile sepsis, chronic bacterial infection, and cancer.
2019 Scientific Article in Cancer Medicine Cancer Med. 8, 1486-1499 (2019)
Comprehensive clinical profiling of the Gauting locoregional lung adenocarcinoma donors.
2019 Meeting abstract in Annals of Surgical Oncology Ann. Surg. Oncol. 26, S192-S192 (2019)
Adhesions are derived from hypoxia responsive mesothelin-positive mesothelial cells and are resolved via targeted therapies.
Methods in Molecular Biology In: Mouse Cell Culture. 2019. 275-295 (Methods Mol. Biol. ; 1940)
The preparation of decellularized mouse lung matrix scaffolds for analysis of lung regenerative cell potential.
2019 Scientific Article in JCI insight JCI insight 4:123971 (2019)
Inhibition of B cell–dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation.
2019 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 294, 5496-5507 (2019)
Melanocortin type 4 receptor-mediated inhibition of A-type K+ current enhances sensory neuronal excitability and mechanical pain sensitivity in rats.
2019 Scientific Article in Small Small 15:1805400 (2019)
Biocompatibility of amine-functionalized silica nanoparticles: The role of surface coverage.
2019 Scientific Article in Nature Communications Nat. Commun. 10:963 (2019)
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics.
2019 Scientific Article in Respiratory Research Respir. Res. 20:30 (2019)
Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: Results from the COSYCONET cohort study.
2019 Review in Frontiers in Microbiology Front. Microbiol. 9:3207 (2019)
"Novel" triggers of herpesvirus reactivation and their potential health relevance.
2019 Scientific Article in Journal of Environmental Management J. Environ. Manage. 233, 417-426 (2019)
Evacuation characteristics of released airborne TiO2 nanomaterial particles under different ventilation rates in a confined environment.
2019 Scientific Article in Journal of Proteomics J. Proteomics 193, 1-9 (2019)
Dissecting the molecular effects of cigarette smoke on proteasome function.
2019 Scientific Article in ACS Nano ACS Nano 13, 1029-1041 (2019)
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.
2019 Scientific Article in European Journal of Immunology Eur. J. Immunol. 49, 351-352 (2019)
B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?
2019 Scientific Article in Clinical & Experimental Allergy Clin. Exp. Allergy 49, 331-340 (2019)
Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization.
2019 Scientific Article in Microbial pathogenesis Microb. Pathog. 126, 109-115 (2019)
The virulence of NDV NA-1 strain regulated by the 3 ' leader or 5 ' trailer sequences.
2019 Scientific Article in IEEE Transactions on Medical Imaging IEEE Trans. Med. Imaging 38, 649-656 (2019)
Dynamic in vivo chest x-ray dark field imaging in mice.
2018 Other: Biografic acticle in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 31, 119-119 (2018)
In Memoriam: Dr. Winfried Moller.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2018, 188 S.
Dissecting the role of proteasome activators in lung biology and disease.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Alteration patterns of tobacco carcinogens in lung adenocarcinoma reveal novel KRAS-addicted candidate oncogenes.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Development of a hybrid alginate-ECM hydrogel as a potential bioink for 3D bioprinting.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Analyzing the role of proteasome activator 200 (PA200) in lung cancer.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
FKBP10 regulates fibroblast migration via synthesis of collagen VI.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Tumor-derived granulocyte chemotactic protein 2 cooperates with neutrophil proteinase 3 to drive lung adenocarcinoma.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Circulating MDSC modulate IPF progression by orchestrating immunosuppressive and pro-fibrotic networks.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Associations between early life exposure to pollen and adolescent lung function are modified by residential greenness.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Novel compounds for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Cigarette smoke induces overexpression of cathepsin S in active smokers with and without COPD.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Late Breaking Abstract - Protein signature stratifies severity of chronic lung disease in preterms after birth.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
The novel notch ligand DNER modulates IFN. Levels in recruited macrophages by enhancing non-canonical notch during COPD progression.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Human anti-Wnt1-inducible signaling protein (WISP) 1 antibodies attenuate experimental lung fibrosis ex vivo.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Preclinical experiments support recent clinical switch to delivered dose during methacholine bronchoprovocation testing.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
A quantitative proteomics profiling of murine lung grafts indicates novel pathways associated with chronic lung allograft dysfunction.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
A proteomic analysis of extracellular matrix from idiopathic pulmonary fibrosis patient-derived fibroblasts in response to transforming growth factor beta 1.
2018 Scientific Article in Science Translational Medicine Sci. Transl. Med. 10:eaan6735 (2018)
Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Increased peribronchiolar and perivascular cysteine protease activity is associated with bronchiolitis obliterans syndrome.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Age-dependent deposition patterns and quantitative biokinetics of inhaled 20nm gold nanoparticles in rat lungs.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Immuno-metabolomic regulation of B cell guided iBALT positioning drives cigarette smoke-induced COPD.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Quantitative MRI measurements to detect pulmonary hypertension in bronchopulomnary dysplasia.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
The progenitor cell marker LGR5 is reduced in epithelial cells in emphysema.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Diagnosis of bronchopulmonary dysplasia using magnetic resonance imaging analysis.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
DPPIV expression in human lung fibroblasts affects phenotypic changes in fibrosis.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Gender specific response of the neonatal lung to postnatal injury.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Pharmacometabolic response to pirfenidone treatment in pulmonary fibrosis detected by high resolution MALDI FTICR-mass spectrometry imaging.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
FK506 binding protein 11, a plasma cell-specific antibody folding catalyst, is increased in pulmonary fibrosis.
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Drug repurposing for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease.
2018 Scientific Article in Human genomics Hum. Genomics 12:50 (2018)
Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine.
2018 Review in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 6, 133 (2018)
Defining skin fibroblastic cell types beyond CD90.
2018 Scientific Article in Respiratory Medicine Respir. Med. 145, 89-94 (2018)
Asthma features in severe COPD: Identifying treatable traits.
2018 Meeting abstract in Arthritis & Rheumatology Arthritis Rheum. 70 (2018)
Characterization of preferential recognition of a chimeric recombinant proteinase 3 variant by anti-neutrophil cytoplasmic antibodies.
2018 Review in Frontiers in Immunology Front. Immunol. 9:979 (2018)
Interleukin-2-inducible T-cell kinase deficiency-new patients, new insight?
2018 Review in Communications Biology Comm. Biol. 1:170 (2018)
Mesothelial to mesenchyme transition as a major developmental and pathological player in trunk organs and their cavities.
2018 Frontiers in Immunology Front. Immunol. 9, 2197:979 (2018)
Erratum: Corrigendum: Interleukin-2-inducible T-cell kinase deficiency-new patients, new insight? (Frontiers in immunology (2018) 9 (979)).
2018 Meeting abstract in Public Health Genomics Public Health Genomics 21, 19-20 (2018)
Trp53 signaling in chemically induced lung adenocarcinoma.
2018 Scientific Article in EBioMedicine EBioMedicine 36, 461-474 (2018)
Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.
2018 Scientific Article in Cytokine Cytokine, DOI: 10.1016/j.cyto.2018.08.006 (2018)
Role of angiopoietins in mesothelioma progression.
2018 Scientific Article in ACS Nano ACS Nano 12, 7771-7790 (2018)
Age-dependent rat lung deposition patterns of inhaled 20 manometer gold nanoparticles and their quantitative biokinetics in adult rats.
2018 Scientific Article in Transboundary and emerging diseases Transboundary Emer. Dis. 65, 1421-1428 (2018)
Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China.
2018 Scientific Article in Aging Aging 10, 2122-2135 (2018)
A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:13008 (2018)
Gas exchange mechanisms in preterm infants on HFOV - a computational approach.
2018 Meeting abstract in Allergy Allergy 73, 10-10 (2018)
Where have all the flowers gone?
2018 Scientific Article in Respiratory Research Respir. Res. 19:175 (2018)
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:12983 (2018)
Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis.
2018 Review in European Respiratory Journal Eur. Respir. J. 52:1601355 (2018)
How to build a lung: Latest advances and emerging themes in lung bioengineering.
2018 Scientific Article in European Respiratory Journal Eur. Respir. J. 52:1702314 (2018)
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.
2018 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 198, 1527-1538 (2018)
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.
2018 Scientific Article in HLA : immune response genetics HLA 92, 24-32 (2018)
Persistence of de novo donor-specific HLA-antibodies after lung transplantation: A potential marker of decreased patient survival.
2018 Scientific Article in Annals of Neurology Ann. Neurol. 84, 315-328 (2018)
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.
2018 Scientific Article in Cancer Research Cancer Res. 78, 3634-3644 (2018)
The autotaxin - lysophosphatidic acid axis promotes lung carcinogenesis.
European Respiratory Review In:. 2018.:180040 (Eur. Respir. Rev. ; 27)
Cell–matrix interactions in lung disease and regeneration: ERS lung science conference 2018 report.
2018 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 315, L682-L696 (2018)
Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
2018 Scientific Article in Lancet Oncology, The Lancet Oncol. 19, 930-939 (2018)
Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): A multicohort analysis.
2018 Scientific Article in Journal of Visualized Experiments J. Vis. Exp.:57302 (2018)
Partial lobular hepatectomy: A surgical model for morphologic liver regeneration.
2018 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 293, 12415-12428 (2018)
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
2018 Scientific Article in Nanoscale Nanoscale 10, 11564-11577 (2018)
Quantum dots cause acute systemic toxicity in lactating rats and growth restriction of offspring.
2018 Scientific Article in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 37, 1021-1028 (2018)
Preservation with alpha(1)-antitrypsin improves primary graft function of murine lung transplants.
2018 Scientific Article in Pflügers Archiv Pflugers Arch. 47, 1231–1241 (2018)
TRPA1 channels: Expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia.
2018 Review in Translational research Transl. Res., DOI: 10.1016/j.trsl.2018.03.003 (2018)
The ubiquitin proteasome system as a potential therapeutic target for systemic sclerosis.
2018 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 315, L87-L101 (2018)
Activation of the NF-kappa B pathway alters the phenotype of MSCs in the tracheal aspirates of preterm infants with severe BPD.
2018 Letter to the Editor in Pediatric Allergy and Immunology Pediatr. Allergy Immunol. 29, 457-457 (2018)
Comments on Filipiak-Pittroff et al.
2018 Scientific Article in Archives of Toxicology Arch. Toxicol. 92, 2163-2174 (2018)
Revisiting the stress paradigm for silica nanoparticles: Decoupling of the anti-oxidative defense, pro-inflammatory response and cytotoxicity.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:6078 (2018)
P52 expression enhances lung cancer progression.
2018 Meeting abstract in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 37, S123-S123 (2018)
Inhibition of neutrophil serine proteases by alpha 1 antitrypsin in during storage preserves primary graft functions of transplanted murine donor lungs.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:6788 (2018)
In vivo dynamic phase-contrast X-ray Imaging using a compact light source.
2018 Scientific Article in Frontiers in Immunology Front. Immunol. 9:1216 (2018)
S100a4 is secreted by alternatively activated alveolar macrophages and promotes activation of lung fibroblasts in pulmonary fibrosis.
2018 Scientific Article in Frontiers in Immunology Front. Immunol. 9:366 (2018)
Enhanced replication of virulent Newcastle disease virus in chicken macrophages is due to polarized activation of cells by inhibition of TLR7.
2018 Scientific Article in Cancer Research Cancer Res. 78, 2939-2951 (2018)
IkB kinase a Is required for development and progression of KRAS-mutant lung adenocarcinoma.
2018 Scientific Article in Respiratory Research Respir. Res. 19:67 (2018)
FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis.
2018 Review in Journal of Innate Immunity J. Innate Immun. 10, 487-501 (2018)
Innate immunity of the lung: From basic mechanisms to translational medicine.
In: Abstract submission (American Thoracic Society (ATS) International Conference 2018, 18-23 May 2018, American Thoracic Society (ATS) International Conference 2018). 2018.:13993 - Fractalkine/CX3CR1 Axis ( ; Annual)
Fractalkine/CX3CR1 axis drives kinetic changes of monocytes in fibrotic Interstitial Lung Disease.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:7547 (2018)
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.
2018 Scientific Article in Nature Cell Biology Nat. Cell Biol. 20, 422-431 (2018)
Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring.
2018 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 10:e8349 (2018)
Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.
2018 Scientific Article in Journal of Medicinal Chemistry J. Med. Chem. 61, 1858-1870 (2018)
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.
2018 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 314, L695-L707 (2018)
Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation.
2018 Scientific Article in JCI insight JCI insight 3:93203 (2018)
mTOR pathway activation drives lung cell senescence and emphysema.
2018 Scientific Article in Journal of Nanoparticle Research J. Nanopart. Res. 20:33 (2018)
A nanomaterial release model for waste shredding using a Bayesian belief network.
2018 Review in Pediatrics Pediatrics 141:e20170889 (2018)
Acid-suppressive drug use during pregnancy and the risk of childhood asthma: A meta-analysis.
2018 Scientific Article in Nature Communications Nat. Commun. 9:672 (2018)
Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:2096 (2018)
X-ray dark-field imaging to depict acute lung inflammation in mice.
2018 Scientific Article in Nature Communications Nat. Commun. 9:288 (2018)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
2018 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 314, L708-L723 (2018)
Distinct niches within the extracellular matrix dictate fibroblast function in (cell free) 3D lung tissue cultures.
2018 Scientific Article in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 59, 77-86 (2018)
Upregulation and nuclear location of MMP28 in alveolar epithelium of idiopathic pulmonary fibrosis.
2018 Editorial in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197, 981-983 (2018)
Epithelial progenitor cells take center stage in lung transplantation.
2018 Review in Pharmacology & Therapeutics. Pharmacol. Ther. 187, 150-166 (2018)
WNT receptor signalling in lung physiology and pathology.
2018 Review in Biotechnology Journal Biotechnol. J. 13:1700341 (2018)
Human pulmonary 3D models for translational research.
2018 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197, 1076-1080 (2018)
Early identification of bronchopulmonary dysplasia using novel biomarkers by proteomic screening.
2018 Scientific Article in Journal of Community Genetics J. Community Genet. 9, 103-116 (2018)
The challenges of the expanded availability of genomic information: An agenda-setting paper.
2018 Scientific Article in Microbial Ecology Microb. Ecol. 75, 529-542 (2018)
Development of a stable lung microbiome in healthy neonatal mice.
2018 Scientific Article in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 37, 268-274 (2018)
Outcome of lung transplantation in idiopathic pulmonary fibrosis with previous anti-fibrotic therapy.
Breathe In:. 2017. 323-326 (Breathe ; 13)
Early career members at the ers lsc 2017: Mechanistic overlap between chronic lung injury and cancer.
2017 Meeting abstract in Molecular Biology of the Cell Mol. Biol. Cell 28 (2017)
MMP28 is overexpressed in bronchial and alveolar epithelial cells in Idiopathic Pulmonary Fibrosis.
2017 Scientific Article in OncoTarget Oncotarget 8, 114019-114030 (2017)
A link between ReIB expression and tumor progression in laryngeal cancer.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:340 (2017)
X-ray dark-field radiography facilitates the diagnosis of pulmonary fibrosis in a mouse model.
2017 Other: Opinion in Allergy Allergy 72, 329-330 (2017)
Linking vitamin D, the microbiome and allergy.
2017 Scientific Article in Annals of Work Exposures and Health Ann. Work Expo. Health 61, 1132-1144 (2017)
Nano-object release during machining of polymer-based manocomposites depends on process factors and the type of nanofiller.
2017 Scientific Article in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 30, 411-424 (2017)
Biokinetics of aerosolized liposomal ciclosporin A in human lung cells in vitro using an air-liquid cell interface exposure system.
2017 Meeting abstract in Multiple Sclerosis Journal Mult. Scler. J. 23, 976-976 (2017)
Pathogenic mechanisms of human autoantibodies against myelin oligodendrocyte glycoprotein.
2017 Editorial in Particle and Fibre Toxicology Part. Fibre Toxicol. 14:52 (2017)
On the pivotal role of dose for particle toxicology and risk assessment: exposure is a poor surrogate for delivered dose.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 12994-12999 (2017)
Cancer cells induce interleukin-22 production from memory CD4+T cells via interleukin-1 to promote tumor growth.
2017 Scientific Article in European Respiratory Review Eur. Respir. Rev. 26:170073 (2017)
Lung ageing and COPD: Is there a role for ageing in abnormal tissue repair?
2017 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 196, 1249-1254 (2017)
A standardized diagnostic ontology for fibrotic interstitial lung disease. An International Working Group Perspective.
2017 Review in Molecular and Cellular Pediatrics Mol. Cell. Pediatr. 4:11 (2017)
The BPD trio? Interaction of dysregulated PDGF, VEGF, and TGF signaling in neonatal chronic lung disease.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:15453 (2017)
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
2017 Scientific Article in Nervenarzt, Der Nervenarzt 88, 1395–1401 (2017)
Entwicklungsneurologie – vernetzte Medizin und neue Perspektiven.
2017 Scientific Article in Nature Communications Nat. Commun. 8:886 (2017)
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
2017 Scientific Article in FASEB Journal FASEB J. 32, 703-716 (2017)
Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis.
2017 Scientific Article in Behavioural Brain Research Behav. Brain Res. 352, 187-196 (2017)
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
2017 Journal of Aerosol Science J. Aerosol Sci. 113, 276 (2017)
Corrigendum to “Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung” [Journal of Aerosol Science 99 (2016) 133–143](S0021850215301166)(10.1016/j.jaerosci.2015.12.006).
2017 Review in European Respiratory Review Eur. Respir. Rev. 26:170021 (2017)
Systems medicine advances in interstitial lung disease.
2017 Scientific Article in Advanced functional materials Adv. Func. Mat. 27:1701956 (2017)
Colloidal stability and surface chemistry are key factors for the composition of the protein corona of inorganic gold nanoparticles.
2017 Meeting abstract in Allergy Allergy 72, 59-59 (2017)
The metabolite D-tryptophan from probiotic bacteria ameliorates allergic airway disease and influences the gut microbiome.
2017 Scientific Article in International Journal of Pharmaceutics Int. J. Pharm. 532, 537-546 (2017)
A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery.
2017 Scientific Article in Immunologic research Immunol. Res. 65, 1065–1073 (2017)
Growth arrest-specific protein 7 regulates the murine M1 alveolar macrophage polarization.
2017 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 9, 1504-1520 (2017)
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.
2017 Scientific Article in Placenta Placenta 57, 144-151 (2017)
Maternal BMI and gestational diabetes alter placental lipid transporters and fatty acid composition.
2017 Scientific Article in Thorax Thorax 72, 1007-1020 (2017)
Pulmonary CCR2+CD4+ T cells are immune regulatory and attenuate lung fibrosis development.
2017 Scientific Article in Molecular & Cellular Oncology Mol. Cell. Oncol. 4:e1345711 (2017)
RAS oncogenes direct metastasis.
2017 Scientific Article in European Respiratory Journal Eur. Respir. J. 50:1602367 (2017)
Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.
2017 Scientific Article in European Respiratory Review Eur. Respir. Rev. 26:170048 (2017)
Shared epithelial pathways to lung repair and disease.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0180859 (2017)
Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:4908 (2017)
Propagation-based phase-contrast x-ray imaging at a compact light source.
2017 Scientific Article in European Respiratory Journal Eur. Respir. J. 50:1601805 (2017)
The instructive extracellular matrix of the lung: Basic composition and alterations in chronic lung disease.
2017 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 196, 1298-1310 (2017)
Deep proteome profiling reveals common prevalence of MZB1-positive plasma B cells in human lung and skin fibrosis.
2017 Scientific Article in Developmental and comparative immunology Dev. Comp. Immunol. 77, 69-76 (2017)
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.
2017 Scientific Article in Pneumologe, Der Pneumologe 14, 244-245 (2017)
Positive Wirkung inhalativer Kortikoide bei Asthma mit < 2 Symptomtagen.
2017 Scientific Article in Nature Communications Nat. Commun. 8:15475 (2017)
Prevalence of sexual dimorphism in mammalian phenotypic traits.
2017 Scientific Article in Immunology Immunology 152, 402-413 (2017)
microRNA cluster 106a~363 is involved in T-Helper 17 (Th17) cell differentiation.
2017 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 14:19 (2017)
Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: Comparison of inhalation versus intra-arterial infusion exposures in mice.
2017 Scientific Article in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 193, 392-401 (2017)
Clinical relevance of the M1b and M1c descriptors from the proposed TNM 8 classification of lung cancer.
2017 Scientific Article in The journal of allergy and clinical immunology J. Allergy Clin. Immunol. 139, 1935-1945.e12 (2017)
Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts.
2017 Scientific Article in Molecular Neurobiology Mol. Neurobiol. 55, 4580–4595 (2017)
Fgf9Y162C mutation alters information processing and social memory in mice.
2017 Scientific Article in Nature Communications Nat. Commun. 8:15205 (2017)
Mutant KRAS promotes malignant pleural effusion formation.
2017 Scientific Article in Immunobiology : Experimental and Clinical Immunobiology 222, 831-840 (2017)
Reprint of: MicroRNA profiling of human intermediate monocytes.
2017 Scientific Article in Allergy Allergy 72, 1962-1971 (2017)
Identification of a plasma miRNA biomarker-signature for allergic asthma: A translational approach.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Monocyte immunophenotyping reflects aberrant activation patterns in interstitial lung disease patients.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Cd82 is a novel mediator of fibroblast proliferation.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Quantitative proteomics reveals novel fibrotic networks of myeloid-derived suppressor cell and monocytes in ipf.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Lymphotoxin-beta-receptor blockade prevents cigarette smoke-induced COPD.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
2d cross-omics integrated enrichment analysis of human and mice COPD lungs reveal novel pathological mechanisms of disease progression.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Loss of the cholesterol metabolizing enzyme Ch25h protects against cigarette smoke-induced COPD.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Different effects of pulmonary rehabilitation in Anxious Vs. Non-Anxious patients with idiopathic pulmonary fibrosis - a pilot study.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Matrix metalloproteinase (mmp)-28 is expressed in alveolar epithelial cells in idiopathic pulmonary fibrosis and increases their proliferation and migration.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Regulation and function of non-canonical Wnt-5a in human lung fibroblasts.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Proteasomal activator 200 (pa200) regulates cellular proliferation: A putative role for Ipf and lung cancer pathogenesis.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Hopx-Wnt crosstalk regulates alveolar homeostasis.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:46026 (2017)
Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.
2017 Scientific Article in Proceedings of SPIE Proc. SPIE 10132:101325L (2017)
First experiences with in-vivo x-ray dark-field imaging of lung cancer in mice.
2017 Scientific Article in European Respiratory Journal Eur. Respir. J. 49:1601315 (2017)
Lung volumes predict survival in patients with chronic lung allograft dysfunction.
2017 Review in Current opinion in Pulmonary Medicine Curr. Opin. Pulm. Med. 23, 290-297 (2017)
Lung carcinogenesis and fibrosis taken together: Just coincidence?
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Effects of nintedanib and pirfenidone on alveolar epithelial cells in 2d and 3d lung cultures.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Time dependant effects of mechanical ventilation and hyperoxia on central signalling pathways in the developing lung identified by comprehensive transcriptome analysis.
2017 Scientific Article in Frontiers in Cellular and Infection Microbiology Front. Cell. Infect. Microbiol. 7:212 (2017)
Dispersal and transmission of avian paramyxovirus serotype 4 among wild birds and domestic poultry.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Skewed alveolar macrophage polarization signature in mice with impaired pulmonary function following carbon nanoparticle exposure.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
An ex vivo human model of idiopathic pulmonary fibrosis using precision cut lung slices.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Cub domain containing protein 1/transforming growth factor-beta 1 cross-talk regulates (myo)fibroblast differentiation.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Wnt activity marks lung progenitors capable of forming spheres in vitro.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Epigenetic histone-1 modulator Hmgn5 regulates cellular apoptosis In COPD pathogenesis.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Activation of the Mtor pathway drives lung cell senescence and emphysema in chronic obstructive pulmonary disease (COPD).
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Orthotopic lung transplantation in a single- mismatch-based mouse model shows signs of chronic lung allograft dysfunction (clad) associated to inducible bronchus-associated lymphoid tissue (ibalt) formation.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Discrimination of pulmonary changes in neonatal chronic lung disease by a new Mri score.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Monocyte-centred inflammatory response driving pulmonary injury in neonatal chronic lung disease.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Enhanced vulnerability of the developing lungs by moderate prenatal cigarette smoke upon postnatal injury.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Deficiency of immunoproteasome subunits increases alternative polarization of alveolar macrophages.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Non-canonical Wnt-5a signaling impairs endogenous lung repair in COPD.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Inflammatory response of lung recruited macrophages is partly regulated by non-canonical notch pathway in chronic obstructive pulmonary diseases (COPD).
2017 Scientific Article in Molecular therapy - Nucleic Acids Mol. Ther. Nucleic Acids 7, 350-365 (2017)
Translation of angiotensin-converting enzyme 2 upon liver- and lung-targeted delivery of optimized chemically modified mRNA.
2017 Scientific Article in Biochemical Pharmacology Biochem. Pharmacol. 131, 52-67 (2017)
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:402 (2017)
X-ray dark-field radiography - in-vivo diagnosis of lung cancer in mice.
2017 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 9, 672-686 (2017)
NRAS destines tumor cells to the lungs.
2017 Scientific Article in Clinical and experimental rheumatology Clin. Exp. Rheumatol. 35, 103, 98-101 (2017)
IgA antibodies to myeloperoxidase in patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss).
2017 Scientific Article in Journal of Heart and Lung Transplantation, The J. Heart Lung Transpl. 36, 957-967 (2017)
The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups.
2017 Scientific Article in Nanotoxicology Nanotox. 11, 454-464 (2017)
Quantitative biokinetics of titanium dioxide nanoparticles after intratracheal instillation in rats (Part 3).
2017 Scientific Article in Nanotoxicology Nanotox. 11, 443-453 (2017)
Quantitative biokinetics of titanium dioxide nanoparticles after oral application in rats (Part 2).
2017 Scientific Article in Nanotoxicology Nanotox. 11, 434-442 (2017)
Quantitative biokinetics of titanium dioxide nanoparticles after intravenous injection in rats (Part 1).
2017 Scientific Article in European Journal of Immunology Eur. J. Immunol. 47, 841-847 (2017)
Chronic schistosomiasis during pregnancy epigenetically reprograms T cell differentiation in offspring of infected mothers.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 3654-3659 (2017)
Localized hepatic lobular regeneration by central-vein-associated lineage-restricted progenitors.
2017 Editorial in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 56, 551-552 (2017)
Linking wnt signaling to mucosal inflammation.
2017 Scientific Article in European Respiratory Journal Eur. Respir. J. 49:1501200 (2017)
Protean proteases: At the cutting edge of lung diseases.
2017 Scientific Article in OncoImmunology OncoImmunology 6:e1256528 (2017)
Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis.
2017 Scientific Article in European Journal of Pharmaceutical Sciences Eur. J. Pharm. Sci. 101, 140-148 (2017)
Multifunctional LUV liposomes decorated for BBB and amyloid targeting. A. In vitro proof-of-concept.
2017 Review in Lancet Respiratory Medicine, The Lancet Resp. Med. 5, 224-234 (2017)
Asthma transition from childhood into adulthood.
2017 Editorial in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195, 546-548 (2017)
Asthma and prenatal inflammation.
2017 Meeting abstract in Cytotherapy Cytotherapy 19, S23-S24 (2017)
Amelioration of lung function and pulmonary tissue regeneration after treatment with AAT-expressing human MSCS in a murine model of elastase-induced emphysema.
2017 Scientific Article in Chemico-Biological Interactions Chem. Biol. Interact. 276, 95-104 (2017)
Regulation of 11β-hydroxysteroid dehydrogenase type 1 following caloric restriction and re-feeding is species dependent.
2017 Scientific Article in Advanced science Adv. Sci. 4:1600238 (2017)
Detecting swelling states of red blood cells by "Cell-fluid coupling spectroscopy".
2017 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 10, 409-423 (2017)
Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 3613-3618 (2017)
Common coding variant in SERPINA1 increases the risk for large artery stroke.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0172716 (2017)
Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.
2017 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 312, L896-L902 (2017)
An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.
2017 Scientific Article in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 57, 77-90 (2017)
A novel antifibrotic mechanism of nintedanib and pirfenidone: Inhibition of collagen fibril assembly.
2017 Scientific Article in European Journal of Pharmaceutical Sciences Eur. J. Pharm. Sci. 102, 180-187 (2017)
Multifunctional LUV liposomes decorated for BBB and amyloid targeting - B. In vivo brain targeting potential in wild-type and APP/PS1 mice.
2017 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 196, 172-185 (2017)
Reduced frizzled receptor 4 expression prevents WNT/β-catenin-driven alveolar lung repair in COPD.
2017 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 14:2 (2017)
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0169223 (2017)
Maternal pre-pregnancy obesity is associated with altered placental transcriptome.
2017 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 214, 143-163 (2017)
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.
2017 Scientific Article in Immunobiology : Experimental and Clinical Immunobiology 222, 587-596 (2017)
MicroRNA profiling of human intermediate monocytes.
2017 Scientific Article in Journal of Applied Physiology J. Appl. Physiol. 122, 191-197 (2017)
Nasal high flow reduces dead space.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, E37-E46 (2017)
Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.
2017 Scientific Article in Biochimica et Biophysica Acta Biochim. Biophys. Acta 1863, 560-568 (2017)
Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.
2017 Scientific Article in Proteomics Proteomics 17:1600243 (2017)
Cigarette smoke alters the secretome of lung epithelial cells.
2017 Scientific Article in Thorax Thorax 72, 1-9 (2017)
The effects of growing up on a farm on adult lung function and allergic phenotypes: An international population-based study.
2017 Scientific Article in The journal of allergy and clinical immunology J. Allergy Clin. Immunol. 139, 1525-1535 (2017)
D-Tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease.
2017 Scientific Article in Journal of Molecular Medicine J. Mol. Med. 95, 169-180 (2017)
Gene expression profiling at birth characterizing the preterm infant with early onset infection.
Pharmacogenetics In:. 2016. 21-33 (Pharmacogenet. Genomics)
Methods of genotyping.
2016 Meeting abstract in European Respiratory Journal Eur. Respir. J. 48, PP104 (2016)
LSC Abstract – Early biomarkers indicating the development of neonatal chronic lung disease defined by clinical and imaging parameters.
2016 Scientific Article in JCI insight JCI insight 1:e90301 (2016)
miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways.
2016 Review in MMW - Fortschritte der Medizin MMW-Fortschr. Med. 158, 76-78 (2016)
Ciguatera: A multifaceted and puzzling disorder.
2016 Meeting abstract in Thorax Thorax 71, A7-A7 (2016)
Mouse lung adenocarcinoma cell lines reveal PRL2C2 as a novel lung tumour promoter.
2016 Meeting abstract in Thorax Thorax 71, A7-A7 (2016)
Osteopontin as an airway epithelial tumour promoter.
2016 Review in Microcirculation Microcirc. 23, 621-625 (2016)
Mechanosensitive G(q/11) protein-coupled receptors mediate myogenic vasoconstriction.
2016 Scientific Article in Respiration Respiration 92, 98-106 (2016)
Insights from the German compassionate use program of nintedanib for the treatment of idiopathic pulmonary fibrosis.
2016 Meeting abstract in Human Gene Therapy. Clinical Development Hum. Gene Ther. 27, A34-A34 (2016)
Amelioration of lung function and pulmonary tissue regeneration after treatment with Alpha-1 antitrypsin (AAT)-expressing mesenchymal stem cells (MSCs) in a murine model of elastase-induced emphysema.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:39074 (2016)
High-resolution short-exposure small-animal laboratory x-ray phase-contrast tomography.
2016 Meeting abstract in Allergy Allergy 71, 31-32 (2016)
Age-dependent regulation of remodeling factors during allergic airway inflammation.
2016 Meeting abstract in European Heart Journal Eur. Heart J. 37, 568-568 (2016)
Selective TSC1 deletion in smooth muscle activates mTOR signaling and induces pulmonary hypertension.
2016 Scientific Article in Medicine & Science in Sports & Exercise Med. Sci. Sports Exerc. 48, 1276-1284 (2016)
Exercise reduces lung fibrosis involving serotonin/akt signaling.
2016 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 291, 8486-8499 (2016)
Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases.
2016 Scientific Article in Pharmacological reviews Pharmacol. Rev. 68, 603-630 (2016)
Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease.
2016 Scientific Article in Nature Communications Nat. Commun. 7:10973 (2016)
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.
2016 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193, 792-800 (2016)
An american thoracic society official research statement: Future directions in lung fibrosis research.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Step-up randomized controlled trial of segmental vapor ablation in patients with severe emphysema: 6 month results.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Monocyte-centred inflammatory response characterizing early stages of Bpd development in the preterm infant.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Chronic bronchitis enhancement in newborn mice from exposure to environmental tobacco smoke.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Insights from a multi-centre real life experience in Germany with nintedanib for the Tteatment of idiopathic pulmonary fibrosis.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Hippo signaling is deranged in idiopathic pulmonary fibrosis and correlates with disease severity.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Effects of nintedanib and pirfenidone on expression and maturation of collagen - A comprehensive analysis.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Predictors of mortality in patients with idiopathic pulmonary fibrosis under clinical practice conditions: Insights-Ipf registry.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Increased alveolar epithelial cell senescence in pulmonary fibrosis.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Regulation of non-canonical Wnt-5a by primary human lung fibroblasts.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Cigarette smoke-induced downregulation of the epithelial cell enriched WNT receptor Fzd4 contributes to reduced Wnt/beta-catenin signaling and alveolar epithelial cell proliferation in COPD.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Proteasome-dependent Mhc I antigen presentation is altered by cigarette smoke.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Reduced expression of the epigenetic regulator Hmgn5 enhances susceptibility to emphysema.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Non-canonical Wnt-5a compromises endogenous lung repair In COPD.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Expression and regulation of glutathione peroxidase 3 in interstitial lung disease.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Proteasome activator 200 (pa200) is dysregulated in fibrotic remodeling of the lung.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Enhanced effects of hyperoxia on Vessel development in newborn mice heterozygote for the bmp receptor 2.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Impact of posaconazol liquid vs. tablet formulation on plasma trough levels in lung transplant recipients.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Decellularized wild type and alpha-galactosyltransferase knockout pig lungs stimulate M2 phenotype in human monocyte/macrophages.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Runt-related transcription factor 2 (runx2) regulates mesenchymal cell differentiation and extracellular matrix production in pulmonary fibrosis.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Peripheral blood myeloid-derived suppressor cells reflect disease status In Ipf.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Wisp1 mediates Il6-dependent proliferation in healthy and Ipf-derived primary human lung fibroblasts.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193:A2368 (2016)
Osteopontin as an airway epithelial tumor promoter.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193:A2330 (2016)
Targeting the mtor signaling pathway to inhibit lung cell senescence In chronic obstructive pulmonary disease (COPD).
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193:A1351 (2016)
Towards standardized airway hyperresponsiveness measurements In mice.
2016 Scientific Article in ERJ Open Research ERJ Open Res. 2:00029-2016 (2016)
Total particulate matter concentration skews cigarette smoke’s gene expression profile.
2016 Scientific Article in Heart Heart 102, 2, ii49-ii56 (2016)
Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK.
2016 Scientific Article in Advanced healthcare materials Adv. Healthc. Mater. 6:1600818 (2016)
Validating metal-organic framework nanoparticles for their nanosafety in diverse biomedical applications.
2016 Scientific Article in Genes Genomes Genetics G3 Genes Genomes Genetics G3 6, 4035-4046 (2016)
The first Scube3 mutant mouse line with pleiotropic phenotypic alterations.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:35413 (2016)
Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis.
2016 Scientific Article in Molecular and Cellular Pediatrics Mol. Cell. Pediatr. 3, 34:34 (2016)
Linking bronchopulmonary dysplasia to adult chronic lung diseases: Role of WNT signaling.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0163420 (2016)
Aerobic exercise attenuated bleomycin-induced lung fibrosis in Th2-dominant mice.
2016 Scientific Article in Cell Chemical Biology Cell Chem. Bio. 23, 1302-1313 (2016)
Systematic identification of pharmacological targets from small-molecule phenotypic screens.
2016 Scientific Article in Mammalian Genome Mamm. Genome 27, 587-598 (2016)
Viable EdnraY129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
2016 Scientific Article in Investigative Radiology Invest. Radiol. 51, 597-601 (2016)
Facilitated diagnosis of pneumothoraces in newborn mice using x-ray dark-field radiography.
2016 Scientific Article in European Respiratory Journal Eur. Respir. J. 48, 1171-1183 (2016)
Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis.
2016 Scientific Article in Chest Chest 150, 1361-1370 (2016)
Translational research in pleural infection and beyond.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:32128 (2016)
The small noncoding RNAs (sncRNAs) of murine gammaherpesvirus 68 (MHV-68) are involved in regulating the latent-to-lytic switch in vivo.
2016 Scientific Article in The journal of allergy and clinical immunology J. Allergy Clin. Immunol. 139, 1343-1354.e6 (2016)
Age dictates a steroid resistant cascade of Wnt5a, transglutaminase-2 and leukotrienes in inflamed airways.
2016 Scientific Article in Biochemical and Biophysical Research Communications Biochem. Biophys. Res. Commun. 477, 1051-1058 (2016)
TAGLN2, a novel regulator involved in Hepatitis B virus transcription and replication.
2016 Scientific Article in Antiviral Research Antiviral Res. 133, 140-144 (2016)
A Raf kinase inhibitor demonstrates antiviral activities both in vitro and in vivo against different genotypes of virulent Newcastle disease virus.
2016 Meeting abstract in Acta Physiologica Acta Physiol. 217, 142-143 (2016)
Targeting the mtor signaling pathway to inhibit lung cell senescence in Chronic Obstructive Pulmonary Disease (COPD).
2016 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 311, L602-L610 (2016)
Cigarette smoke causes acute airways disease and exacerbates chronic obstructive lung disease in neonatal mice.
2016 Scientific Article in BMC Cancer BMC Cancer 16:409 (2016)
Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases.
2016 Scientific Article in International Journal of Hygiene and Environmental Health Int. J. Hyg. Environ. Health 219, 343-348 (2016)
No further increase in the parent reported prevalence of allergies in Bavarian preschool children: Results from three cross-sectional studies.
2016 Scientific Article in Respiratory Research Respir. Res. 17:83 (2016)
Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:29952 (2016)
Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease.
2016 Scientific Article in BMC Pulmonary Medicine BMC Pulm. Med. 16:96 (2016)
Heart rate response during 6-minute walking testing predicts outcome in operable chronic thromboembolic pulmonary hypertension.
2016 Scientific Article in Tissue Engineering / Part C: Methods Tissue Eng. Part C Meth. 22, 418-428 (2016)
Residual detergent detection method for nondestructive cytocompatibility evaluation of decellularized whole lung scaffolds.
2016 Review in Molecular and Cellular Pediatrics Mol. Cell. Pediatr. 3:24 (2016)
Early injury of the neonatal lung contributes to premature lung aging: A hypothesis.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:28207 (2016)
IgG1 Fc N-glycan galactosylation as a biomarker for immune activation.
2016 Scientific Article in Journal of Cystic Fibrosis J. Cyst. Fibros. 15, 340-349 (2016)
Microbial colonization and lung function in adolescents with cystic fibrosis.
2016 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 311, L328-L336 (2016)
Proteasome function shapes innate and adaptive immune responses.
2016 Editorial in Thorax Thorax 71, 675-676 (2016)
Repositioning compounds from cancer drug discovery to IPF: PI3K inhibition.
2016 Scientific Article in Tissue Engineering / Part C: Methods Tissue Eng. Part C Meth. 22, 725-739 (2016)
Comparative study to the use of decellularized alpha-Gal KO pig lungs for xenogeneic lung transplantation.
2016 Scientific Article in Cell Reports Cell Rep. 16, 120-132 (2016)
Neutrophil-derived IL-1β impairs the efficacy of NF-κB inhibitors against lung cancer.
2016 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 13:33 (2016)
No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice.
2016 Scientific Article in European Respiratory Review Eur. Respir. Rev. 25, 189-198 (2016)
Malignant pleural effusion: From bench to bedside.
2016 Scientific Article in European Respiratory Journal Eur. Respir. J. 48, 92-103 (2016)
Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography.
2016 Meeting abstract in Biophysical Journal Biophys. J. 110, 134A (2016)
'Optical shaking' of red blood cells: A strategy to measure cell-fluid coupling with optical tweezers.
2016 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 291, 8486-8499 (2016)
Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases.
2016 Scientific Article in Journal of Aerosol Science J. Aerosol Sci. 99, 133-143 (2016)
Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung.
2016 Scientific Article in International Journal of Epidemiology Int. J. Epidemiol. 46, 25-26 (2016)
Cohort profile: Melbourne Atopy Cohort study (MACS).
2016 Scientific Article in Analyst, The Analyst 141, 4293-4298 (2016)
Early apoptosis real-time detection by label-free SERS based on externalized phosphatidylserine.
2016 Scientific Article in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 29, 107-126 (2016)
Bridging the gap between science and clinical efficacy: Physiology, imaging, and modeling of aerosols in the lung.
2016 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 17:485 (2016)
Do variants in GSTs modify the association between traffic air pollution and asthma in adolescence?
2016 Scientific Article in Data in Brief Data Brief 7, 1175-1178 (2016)
Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments.
2016 Review in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 55, 309-322 (2016)
Immune mechanisms in pulmonary fibrosis.
2016 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 291, 13147-13159 (2016)
Inhibition of proteasome activity induces formation of alternative proteasome complexes.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:24269 (2016)
Visualization of neonatal lung injury associated with mechanical ventilation using X-ray dark-field radiography.
2016 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 310, L909-L918 (2016)
Absence of TNF-α enhances inflammatory response in the newborn lung undergoing mechanical ventilation.
2016 Scientific Article in Nanoscale Nanoscale 8, 8058-8069 (2016)
Applicability of avidin protein coated mesoporous silica nanoparticles as drug carriers in the lung.
2016 Scientific Article in Acta Biomaterialia Acta Biomater. 32, 256-263 (2016)
Understanding nature's residual strain engineering at the human dentine-enamel junction interface.
2016 Scientific Article in European Respiratory Journal Eur. Respir. J. 47, 1842-1854 (2016)
"Scar-cinoma": Viewing the fibrotic lung mesenchymal cell in the context of cancer biology.
2016 Scientific Article in Journal of Toxicology and Environmental Health, Part B: Critical reviews J. Toxicol. Environ. Health B Crit. Rev. 19, 1-28 (2016)
A multilaboratory toxicological assessment of a panel of 10 engineered nanomaterials to human health - ENPRA project - the highlights, limitations, and current and future challenges.
2016 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 310, 919-927 (2016)
Systematic phenotyping and correlation of biomarkers with lung function and histology in lung fibrosis.
2016 Scientific Article in Nature Communications Nat. Commun. 7:10973 (2016)
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.
2016 Scientific Article in Cell Death and Differentiation Cell Death Differ. 23, 1026-1037 (2016)
Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0147388 (2016)
Association of forced vital capacity with the developmental gene NCOR2.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:22856 (2016)
PEGylated substrates of NSP4 protease: A tool to study protease specificity.
2016 Scientific Article in JAMA: Journal of the American Medical Association JAMA 315, 672-681 (2016)
Association between interstitial lung abnormalities and all-cause mortality.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:20547 (2016)
WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.
2016 Scientific Article in International Immunology Int. Immunol. 28, 473-487 (2016)
A novel role of MMP-13 for murine DC function: Its inhibition dampens T cell activation.
2016 Scientific Article in International Journal of Biochemistry & Cell Biology, The Int. J. Biochem. Cell Biol. 74, 44-59 (2016)
Surface proteome analysis identifies platelet derived growth factor receptor-alpha as a critical mediator of transforming growth factor-beta-induced collagen secretion.
2016 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193, 1230-1241 (2016)
Impairment of immunoproteasome function by cigarette smoke and in COPD.
2016 Review in Pflügers Archiv Pflugers Arch. 468, 1-2 (2016)
Oxygen physiology: Sensors and ion channels.
2016 Scientific Article in FASEB Journal FASEB J. 30, 1823-1835 (2016)
TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8.
2016 Scientific Article in International Journal of Pharmaceutics Int. J. Pharm. 500, 227-235 (2016)
Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice.
2016 Scientific Article in Applied and Environmental Microbiology Appl. Environ. Microbiol. 82, 1530-1536 (2016)
High genetic diversity of Newcastle disease virus in wild and domestic birds in Northeastern China from 2013 to 2015 reveals potential epidemic trends.
2016 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 145, 201-211 (2016)
Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging.
2016 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193, 847-860 (2016)
Membrane-anchored serine protease matriptase is a trigger of pulmonary fibrogenesis.
2016 Scientific Article in FEBS Journal, The FEBS J. 283, 498-509 (2016)
Analysis of urinary cathepsin C for diagnosing Papillon-Lefèvre syndrome.
2016 Scientific Article in Clinical Science Clin. Sci. 130, 273-287 (2016)
Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema.
2016 Scientific Article in Journal of Cystic Fibrosis J. Cyst. Fibros. 15, 325-331 (2016)
A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation.
2016 Scientific Article in Mucosal Immunology Mucosal Immunol. 9, 240-253 (2016)
A protective role for IL-13 receptor α 1 in bleomycin-induced pulmonary injury and repair.
2016 Scientific Article in OncoTarget Oncotarget 7, 30068-30083 (2016)