Phototherapy (Hyperthermia and Photodynamic therapy)

Motivation

NIR light enables phototherapy with minimal toxic side effects and high penetration into the biological tissues. Importantly, the dose of NIR light can be regulated or improved for different aspects. In NIR-based phototherapy, the cytotoxic effects are mainly observed due to the direct cellular damage, increased vascular permeability or damage, immune response, and controlled drug delivery.

Research focus

• Cancer treatment with hyperthermia
• Photodynamic cancer therapy
• Monitoring of photoimmunotherapy using MSOT
• MSOT-based monitoring of phototherapy effects on the tissue microenvironment
• Monitoring targeted drug delivery and therapeutic response using photoactivatable agents.