All IDC Publications
Rostomyan, L. ; Adrian, F.D. ; Pellegata, N.S. ; Potorac, I. ; Betea, D. ; Castermans, E. ; Christ, E. ; Beckers, A.
Long-term management of resistant acromegaly with pasireotide LAR in 2 cases with a familial AIP mutation.Krahmer, N. ; Najafi, B. ; Quagliariini, F. ; Uhlenhaut, N.H. ; Zeigerer, A. ; Borner, G.H. ; Mann, M.
Proteomics identifies organelle specific phosphorylation and reveals major subcellular reorganization in the progression of NAFLD.Giroud, M. ; Scheideler, M.
Long non-coding RNAs in metabolic organs and energy homeostasis.Pereira, M.G. ; Dyar, K.A. ; Nogara, L. ; Solagna, F. ; Marabita, M. ; Baraldo, M. ; Chemello, F. ; Germinario, E. ; Romanello, V. ; Nolte, H. ; Blaauw, B.
Comparative analysis of muscle hypertrophy models reveals divergent gene transcription profiles and points to translational regulation of muscle growth through increased mTOR signaling.Hidmark, A.S. ; Nawroth, P.P. ; Fleming, T.
Analysis of immune cells in single sciatic nerves and dorsal root ganglion from a single mouse using flow cytometry.Marquardt, A. ; Al-Dabet, M.M. ; Ghosh, S. ; Kohli, S. ; Manoharan, J. ; Elwakiel, A. ; Gadi, I. ; Bock, F. ; Nazir, S. ; Wang, H. ; Lindquist, J.A. ; Nawroth, P.P. ; Madhusudhan, T. ; Mertens, P.R. ; Shahzad, K. ; Isermann, B.
Farnesoid X receptor agonism protects against diabetic tubulopathy: Potential add-on therapy for diabetic nephropathy.Kumar, V. ; Fleming, T. ; Terjung, S. ; Gorzelanny, C. ; Gebhardt, C. ; Agrawal, R. ; Mall, M.A. ; Ranzinger, J. ; Zeier, M. ; Madhusudhan, T. ; Ranjan, S. ; Isermann, B. ; Liesz, A. ; Deshpande, D. ; Häring, H.-U. ; Biswas, S.K. ; Reynolds, P.R. ; Hammes, H.P. ; Peperkok, R. ; Angel, P. ; Herzig, S. ; Nawroth, P.P.
Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.Rios Garcia, M. ; Steinbauer, B. ; Srivastava, K. ; Singhal, M. ; Mattijssen, F. ; Maida, A. ; Christian, S. ; Hess-Stumpp, H. ; Augustin, H.G. ; Müller-Decker, K. ; Nawroth, P.P. ; Herzig, S. ; Berriel Diaz, M.
Acetyl-CoA carboxylase 1-dependent protein acetylation controls breast cancer metastasis and recurrence.Scheideler, M. ; Herzig, S. ; Georgiadi, A.
Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes.Morgenstern, J. ; Fuchs, B. ; Schumacher, D. ; Herzig, S. ; Freichel, M. ; Nawroth, P.P. ; Fleming, T.
Loss of glyoxalase 1 in various mammalian cells is associated with an increased resistance against environmental stressors.Nawroth, P.P. ; Bendszus, M. ; Pham, M. ; Jende, J. ; Heiland, S. ; Ries, S. ; Schumann, C. ; Schmelz, M. ; Schuh-Hofer, S. ; Treede, R.D. ; Kuner, R. ; Oikonomou, D. ; Groener, J.B. ; Kopf, S.
The quest for more research on painful diabetic neuropathy.Clauß, K. ; Popp, A.P. ; Schulze, L. ; Hettich, J. ; Reisser, M. ; Escoter Torres, L. ; Uhlenhaut, N.H. ; Gebhardt, J.C.M.
DNA residence time is a regulatory factor of transcription repression.Kumar, V. ; Sulaj, A. ; Fleming, T. ; Nawroth, P.P.
Purification and Characterization of the Soluble form of the Receptor for Advanced Glycation End-Products (sRAGE): A Novel Fast, Economical and Convenient Method.Pfurr, S. ; Chu, Y.H. ; Bohrer, C. ; Greulich, F. ; Beattie, R. ; Mammadzada, K. ; Hils, M. ; Arnold, S.J. ; Taylor, V. ; Schachtrup, K. ; Uhlenhaut, N.H. ; Schachtrup, C.
The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development.Laemmermann, I. ; Terlecki-Zaniewicz, L. ; Weinmuellner, R. ; Schosserer, M. ; Berlin, I. ; Morizot, F. ; Lejeune, F. ; Fuzzati, N. ; Almaraz, J.C.H. ; Scheideler, M. ; Rietveld, M. ; El Ghalbzouri, A. ; Tschachler, E. ; Gruber, F. ; Grillari, J.
Blocking negative effects of senescence in human skin fibroblasts with a plant extract.Terlecki-Zaniewicz, L. ; Pils, V. ; Laemmermann, I. ; Latreille, J. ; Pum, D. ; Scheideler, M. ; Almaraz, J.C.H. ; Morizot, F. ; Gruber, F. ; Grillari, J.
Senescent human fibroblasts selectively secrete miRNAs in extracellular vesicles and modulate keratinocyte functionality during skin aging.Zemva, J. ; Fink, C.A. ; Fleming, T.H. ; Schmidt, L. ; Loft, A. ; Herzig, S. ; Knieß, R.A. ; Mayer, M. ; Bukau, B. ; Nawroth, P.P. ; Tyedmers, J.
Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux.Pfaff, D.H. ; Fleming, T. ; Nawroth, P.P. ; Teleman, A.A.
Reply to Richarme: Evidence against a role of DJ-1 in methylglyoxal detoxification.Dyar, K.A. ; Eckel-Mahan, K.L.
Circadian metabolomics in time and space.Niopek, K. ; Üstünel, B.E. ; Seitz, S. ; Sakurai, M. ; Zota, A. ; Mattijssen, F. ; Wang, X. ; Sijmonsma, T. ; Feuchter, Y. ; Gail, A.M. ; Leuchs, B. ; Niopek, D. ; Staufer, O. ; Brune, M. ; Sticht, C. ; Gretz, N. ; Müller-Decker, K. ; Hammes, H.P. ; Nawroth, P.P. ; Fleming, T. ; Conkright, M.D. ; Blüher, M. ; Zeigerer, A. ; Herzig, S. ; Berriel Diaz, M.
A hepatic GAbp-AMPK axis links inflammatory signaling to systemic vascular damage.Maida, A. ; Chan, J.S.K. ; Sjøberg, K.A. ; Zota, A. ; Schmoll, D. ; Kiens, B. ; Herzig, S. ; Rose, A.J.
Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.Vegiopoulos, A. ; Rohm, M. ; Herzig, S.
Adipose tissue: Between the extremes.Scheideler, M. ; Herzig, S.
Let's burn whatever you have: Mitofusin 2 metabolically re-wires brown adipose tissue.Hidmark, A.S. ; Spanidis, I. ; Fleming, T.H. ; Volk, N. ; Eckstein, V. ; Groener, J.B. ; Kopf, S. ; Nawroth, P.P. ; Oikonomou, D.
Electrical muscle stimulation induces an increase of VEGFR2 on circulating hematopoietic stem cells in patients with diabetes.Metzendorf, C. ; Zeigerer, A. ; Seifert, S. ; Sparla, R. ; Najafi, B. ; Canonne-Hergaux, F. ; Zerial, M. ; Muckenthaler, M.U.
Acute loss of the hepatic endo-lysosomal system in vivo causes compensatory changes in iron homeostasis.Davari, K. ; Lichti, J. ; Gallus, C. ; Greulich, F. ; Uhlenhaut, N.H. ; Heinig, M. ; Friedel, C.C. ; Glasmacher, E.
Rapid genome-wide recruitment of RNA polymerase II drives transcription, splicing, and translation events during T cell responses.Brings, S. ; Fleming, T. ; Freichel, M. ; Muckenthaler, M.U. ; Herzig, S. ; Nawroth, P.P.
Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention.Hidmark, A.S. ; Nawroth, P.P. ; Fleming, T.
STZ causes depletion of immune cells in sciatic nerve and dorsal root ganglion in experimental diabetes.Duteil, D. ; Tosic, M. ; Willmann, D. ; Georgiadi, A. ; Kanouni, T. ; Schuele, R.
Lsd1 prevents age-programed loss of beige adipocytes.Sulaj, A. ; Kopf, S. ; Gröne, E.F. ; Gröne, H.J. ; Hoffmann, S. ; Schleicher, E. ; Häring, H.-U. ; Schwenger, V. ; Herzig, S. ; Fleming, T. ; Nawroth, P.P. ; von Bauer, R.
ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy.Amri, E.Z. ; Scheideler, M.
Small non coding RNAs in adipocyte biology and obesity.Fischer, K. ; Ruiz, H.H. ; Jhun, K. ; Finan, B. ; Oberlin, D.J. ; van der Heide, V. ; Kalinovich, A.V. ; Petrovic, N. ; Wolf, Y. ; Clemmensen, C. ; Shin, A.C. ; Divanovic, S. ; Brombacher, F. ; Glasmacher, E. ; Keipert, S. ; Jastroch, M. ; Nagler, J. ; Schramm, K.-W. ; Medrikova, D. ; Collden, G. ; Woods, S.C. ; Herzig, S. ; Homann, D. ; Jung, S. ; Nedergaard, J. ; Cannon, B. ; Tschöp, M.H. ; Müller, T.D. ; Buettner, C.
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis.Giménez-Dejoz, J. ; Weber, S. ; Barski, O.A. ; Möller, G. ; Adamski, J. ; Parés, X. ; Porté, S. ; Farrés, J.
Characterization of AKR1B16, a novel mouse aldo-keto reductase.Kasperk, C. ; Georgescu, C. ; Nawroth, P.P.
Diabetes mellitus and bone metabolism.Brings, S. ; Fleming, T. ; de Buhr, S. ; Beijer, B. ; Lindner, T. ; Wischnjow, A. ; Kender, Z. ; Peters, V. ; Kopf, S. ; Haberkorn, U. ; Mier, W. ; Nawroth, P.P.
A scavenger peptide prevents methylglyoxal induced pain in mice.Khan, A. ; Dellago, H. ; Terlecki-Zaniewicz, L. ; Karbiener, M. ; Weilner, S. ; Hildner, F. ; Steininger, V. ; Gabriel, C. ; Mück, C. ; Jansen-Dürr, P. ; Hacobian, A. ; Scheideler, M. ; Grillari-Voglauer, R. ; Schosserer, M. ; Grillari, J.
SNEVhPrp19/hPso4 regulates adipogenesis of human adipose stromal cells.Loft, A. ; Forss, I. ; Mandrup, S.
Genome-wide insights into the development and function of thermogenic adipocytes.Pfaff, D.H. ; Fleming, T. ; Nawroth, P.P. ; Teleman, A.A.
Evidence against a role for the parkinsonism-associated protein DJ-1 in methylglyoxal detoxification.Zeigerer, A. ; Wuttke, A. ; Marsico, G. ; Seifert, S. ; Kalaidzidis, Y. ; Zerial, M.
Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance.Lee, M.S. ; Minaskan Karabid, N. ; Wiedemann, T. ; Irmler, M. ; Beckers, J. ; Yousefi, B.H. ; Kaissis, G. ; Braren, R. ; Laitinen, I. ; Pellegata, N.S.
Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.Mendler, M. ; Riedinger, C. ; Schlotterer, A. ; Volk, N. ; Fleming, T. ; Herzig, S. ; Nawroth, P.P. ; Morcos, M.
Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan.Stahl, V. ; Maier, F. ; Freitag, M.T. ; Floca, R.O. ; Berger, M.C. ; Umathum, R. ; Berriel Diaz, M. ; Herzig, S. ; Weber, M.A. ; Dimitrakopoulou-Strauss, A. ; Rink, K. ; Bachert, P. ; Ladd, M.E. ; Nagel, A.M.
In vivo assessment of cold stimulation effects on the fat fraction of brown adipose tissue using DIXON MRI.Borsari, S. ; Pardi, E. ; Pellegata, N.S. ; Lee, M.S. ; Saponaro, F. ; Torregrossa, L. ; Basolo, F. ; Paltrinieri, E. ; Zatelli, M.C. ; Materazzi, G. ; Miccoli, P. ; Marcocci, C. ; Cetani, F.
Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas.