All IDC Publications
Willemsen, N. ; Bartelt, A.
Breathe and burn: Novel roles for myoglobin in thermogenesis.Wackerhage, H. ; Dyar, K.A. ; Schönfelder, M.
Altitude, temperature, circadian rhythms and exercise.Maalmi, H. ; Strom, A. ; Petrera, A. ; Hauck, S.M. ; Strassburger, K. ; Kuss, O. ; Zaharia, O.P. ; Bönhof, G.J. ; Rathmann, W. ; Trenkamp, S. ; Burkart, V. ; Szendroedi, J. ; Ziegler, D. ; Roden, M. ; Herder, C.
Serum neurofilament light chain: A novel biomarker for early diabetic sensorimotor polyneuropathy.Gulde, S. ; Foscarini, A. ; April-Monn, S.L. ; Genio, E. ; Marangelo, A. ; Satam, S. ; Helbling, D. ; Falconi, M. ; Toledo, R.A. ; Schrader, J. ; Perren, A. ; Marinoni, I. ; Pellegata, N.S.
Combined targeting of pathogenetic mechanisms in pancreatic neuroendocrine tumors elicits synergistic antitumor effects.Willemsen, N. ; Kotschi, S. ; Bartelt, A.
Fire up the pyre: Inosine thermogenic signaling for obesity therapy.Vos, D.Y. ; Wijers, M. ; Smit, M. ; Huijkman, N. ; Kloosterhuis, N.J. ; Wolters, J.C. ; Tissink, J.J. ; Pronk, A.C.M. ; Kooijman, S. ; Rensen, P.C.N. ; Kuivenhoven, J.A. ; Van De Sluis, B.
Cargo-specific role for retriever subunit VPS26C in hepatocyte lipoprotein receptor recycling to control postprandial triglyceride-rich lipoproteins.Al-Saoudi, E. ; Christensen, M.M.B. ; Nawroth, P.P. ; Fleming, T. ; Hommel, E.E. ; Jørgensen, M.E. ; Fleischer, J. ; Hansen, C.S.
Advanced glycation end-products are associated with diabetic neuropathy in young adults with type 1 diabetes.Haythorne, E. ; Lloyd, M. ; Walsby-Tickle, J. ; Tarasov, A.I. ; Sandbrink, J. ; Portillo, I. ; Terron Exposito, R. ; Sachse, G. ; Cyranka, M. ; Rohm, M. ; Rorsman, P. ; McCullagh, J. ; Ashcroft, F.M.
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.Ansari, S.A. ; Dantoft, W. ; Ruiz-Orera, J. ; Syed, A.P. ; Blachut, S. ; Van Heesch, S. ; Hübner, N. ; Uhlenhaut, N.H.
Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes.Pellegata, N.S. ; Berriel Diaz, M. ; Rohm, M. ; Herzig, S.
Obesity and cancer-extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases.Puljung, M. ; Haythorne, E. ; Rohm, M. ; Vedovato, N.
Editorial: Ion channels and transporters in diabetes and metabolic diseases.Gilleron, J. ; Zeigerer, A.
Author Correction: Endosomal trafficking in metabolic homeostasis and diseases (Nature Reviews Endocrinology, (2022), 10.1038/s41574-022-00737-9).Pigazzani, F. ; Gorni, D. ; Dyar, K.A. ; Pedrelli, M. ; Kennedy, G. ; Costantino, G. ; Bruno, A. ; Mackenzie, I.R. ; MacDonald, T.M. ; Tietge, U.J.F. ; George, J.
The prognostic value of derivatives-reactive oxygen metabolites (d-ROMs) for cardiovascular disease events and mortality: A review.Brecklinghaus, T. ; Albrecht, W. ; Duda, J. ; Kappenberg, F. ; Gründler, L. ; Edlund, K. ; Marchan, R. ; Ghallab, A. ; Cadenas, C. ; Rieck, A. ; Vartak, N. ; Tolosa, L. ; Castell, J.V. ; Gardner, I. ; Halilbasic, E. ; Trauner, M. ; Ullrich, A. ; Zeigerer, A. ; Demirci Turgunbayer, Ö. ; Damm, G. ; Seehofer, D. ; Rahnenführer, J. ; Hengstler, J.G.
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay.Petrus, P. ; Cervantes, M. ; Samad, M. ; Sato, T. ; Chao, A. ; Sato, S. ; Koronowski, K.B. ; Park, G. ; Alam, Y. ; Mejhert, N. ; Seldin, M.M. ; Monroy Kuhn, J.M. ; Dyar, K.A. ; Lutter, D. ; Baldi, P. ; Kaiser, P. ; Jang, C. ; Sassone-Corsi, P.
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.Matta Pereira, L. ; de Faria, C.C. ; De Oliveira, D.F. ; Andrade, I.S. ; Lima-Junior, N.C. ; Gregorio, B.M. ; Takiya, C.M. ; Freitas Ferreira, A.C. ; Nascimento, J.H.M. ; de Carvalho, D.P. ; Bartelt, A. ; Maciel, L. ; Fortunato, R.S.
Exercise improves redox homeostasis and mitochondrial function in white adipose tissue.Herzig, S.
Hunger metabolism - from molecular basis to therapeutic use Werner Creutzfeldt prize 2022-a brief overview of the award winner Stephan Herzig.Billeter, A.T. ; Scheurlen, K.M. ; Israel, B. ; Straub, B.B. ; Schirmacher, P. ; Kopf, S. ; Nawroth, P.P. ; Müller-Stich, B.P.
Gastric bypass resolves metabolic dysfunction-associated fatty liver disease (MAFLD) in low-BMI patients: A prospective cohort study.Quarta, C. ; Stemmer, K. ; Novikoff, A. ; Yang, B. ; Klingelhuber, F. ; Harger, A. ; Bakhti, M. ; Bastidas-Ponce, A. ; Baugé, E. ; Campbell, J.E. ; Capozzi, M.E. ; Clemmensen, C. ; Collden, G. ; Cota, P. ; Douros, J. ; Drucker, D.J. ; Dubois, B. ; Feuchtinger, A. ; García-Cáceres, C. ; Grandl, G. ; Hennuyer, N. ; Herzig, S. ; Hofmann, S.M. ; Knerr, P.J. ; Kulaj, K. ; Lalloyer, F. ; Lickert, H. ; Liskiewicz, A. ; Liskiewicz, D. ; Maity-Kumar, G. ; Perez-Tilve, D. ; Prakash, S. ; Sanchez-Garrido, M.A. ; Zhang, Q. ; Staels, B. ; Krahmer, N. ; DiMarchi, R.D. ; Tschöp, M.H. ; Finan, B. ; Müller, T.D.
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.Demir, S. ; Wolff, G. ; Wieder, A. ; Maida, A. ; Bühler, L. ; Brune, M. ; Hautzinger, O. ; Feuchtinger, A. ; Poth, T. ; Szendroedi, J. ; Herzig, S. ; Ekim Üstünel, B.
TSC22D4 interacts with Akt1 to regulate glucose metabolism.Sekar, R. ; Motzler, K. ; Kwon, Y. ; Novikoff, A. ; Jülg, J. ; Najafi, B. ; Wang, S. ; Seitz, S. ; Hass, D, ; Gancheva, S. ; Kahl, S. ; Yang, B. ; Finan, B. ; Schwarz, K. ; Okun, J.G. ; Roden, M. ; Blüher, M. ; Müller, T.D. ; Krahmer, N. ; Behrends, C. ; Plettenburg, O. ; Miaczynska, M. ; Herzig, S. ; Zeigerer, A.
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.Rios Garcia, M. ; Meissburger, B. ; Chan, J. ; de Guia, R.M. ; Mattijssen, F. ; Roessler, S. ; Birkenfeld, A.L. ; Raschzok, N. ; Riols, F. ; Tokarz, J. ; Giroud, M. ; Gil Lozano, M. ; Hartleben, G. ; Nawroth, P.P. ; Haid, M. ; López, M. ; Herzig, S. ; Berriel Diaz, M.
Trip13 depletion in liver cancer induces a lipogenic response contributing to plin2-dependent mitotic cell death.Zweck, E. ; Scheiber, D. ; Schultheiss, H.P. ; Kuss, O. ; Kelm, M. ; Roden, M. ; Westenfeld, R. ; Szendroedi, J.
Impaired myocardial mitochondrial respiration in humans with prediabetes: A footprint of prediabetic cardiomyopathy.Walth, A.A. ; Herzig, S. ; Rohm, M.
Nuclear receptors in energy metabolism.Willemsen, N. ; Arigoni, I. ; Studencka-Turski, M. ; Kruger, E. ; Bartelt, A.
Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3.Kender, Z. ; Groener, J.B. ; Jende, J.M.E. ; Kurz, F.T. ; Fleming, T. ; Sulaj, A. ; Schuh-Hofer, S. ; Treede, R.D. ; Bendszus, M. ; Szendroedi, J. ; Nawroth, P.P. ; Kopf, S.
Diabetic neuropathy is a generalized phenomenon with impact on hand functional performance and quality of life.Artati, A. ; Prehn, C. ; Lutter, D. ; Dyar, K.A.
Untargeted and targeted circadian metabolomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and flow injection-electrospray ionization-tandem mass spectrometry (FIA-ESI-MS/MS).Smith, J.G. ; Sato, T. ; Shimaji, K. ; Koronowski, K.B. ; Petrus, P. ; Cervantes, M. ; Kinouchi, K. ; Lutter, D. ; Dyar, K.A. ; Sassone-Corsi, P.
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain.Mishima, E. ; Ito, J. ; Wu, Z. ; Nakamura, T. ; Wahida, A. ; Doll, S. ; Tonnus, W. ; Nepachalovich, P. ; Eggenhofer, E. ; Aldrovandi, M. ; Henkelmann, B. ; Yamada, K.i. ; Wanninger, J. ; Zilka, O. ; Sato, E. ; Feederle, R. ; Hass, D, ; Maida, A. ; Mourao, A. ; Linkermann, A. ; Geissler, E.K. ; Nakagawa, K. ; Abe, T. ; Fedorova, M. ; Proneth, B. ; Pratt, D.A. ; Conrad, M.
A non-canonical vitamin K cycle is a potent ferroptosis suppressor.Wang, K. ; Schütze, I. ; Gulde, S. ; Bechmann, N. ; Richter, S. ; Helm, J. ; Lauseker, M. ; Maurer, J. ; Reul, A. ; Spoettl, G. ; Klink, B. ; William, D. ; Knösel, T. ; Friemel, J. ; Bihl, M. ; Weber, A. ; Fankhauser, M. ; Schober, L. ; Vetter, D. ; Broglie Däppen, M. ; Ziegler, C. ; Ullrich, M. ; Pietzsch, J. ; Bornstein, S.R. ; Lottspeich, C. ; Kroiss, M. ; Fassnacht, M. ; Wenter, V.U.J. ; Ladurner, R. ; Hantel, C. ; Reincke, M. ; Eisenhofer, G. ; Grossman, A.B. ; Pacak, K. ; Beuschlein, F. ; Auernhammer, C.J. ; Pellegata, N.S. ; Nölting, S.
Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures.van Eenige, R. ; In Het Panhuis, W. ; Schönke, M. ; Jouffe, C. ; Devilee, T.H. ; Siebeler, R. ; Streefland, T.C.M. ; Sips, H.C.M. ; Pronk, A.C.M. ; Vorderman, R.H.P. ; Mei, H. ; van Klinken, J.B. ; van Weeghel, M. ; Uhlenhaut, N.H. ; Kersten, S. ; Rensen, P.C.N. ; Kooijman, S.
Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.Wolff, G. ; Sakurai, M. ; Mhamane, A. ; Troullinaki, M. ; Maida, A. ; Deligiannis, I.K. ; Yin, K. ; Weber, P. ; Morgenstern, J. ; Wieder, A. ; Kwon, Y. ; Sekar, R. ; Zeigerer, A. ; Roden, M. ; Blüher, M. ; Volk, N. ; Poth, T. ; Hackert, T. ; Wiedmann, L. ; De Angelis Rigotti, F. ; Rodriguez-Vita, J. ; Fischer, A. ; Mukthavaram, R. ; Limphong, P. ; Tachikawa, K. ; Karmali, P. ; Payne, J. ; Chivukula, P. ; Ekim Üstünel, B. ; Martinez Jimenez, C.P. ; Szendrödi, J. ; Nawroth, P.P. ; Herzig, S.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.Engelhard, C.A. ; Huang, C. ; Khani, S. ; Kasparek, P. ; Prochazka, J. ; Rozman, J. ; Reguera, D.P. ; Sedlacek, R. ; Kornfeld, J.W.
Comprehensive transcriptional profiling and mouse phenotyping reveals dispensable role for adipose tissue selective long noncoding RNA Gm15551.Chen, Y. ; Fernandez, E.A. ; Röger, C. ; Lopez-Mejia, I.C. ; Fajas Coll, L. ; Ji, H.
Adipocyte-specific CDK7 ablation leads to progressive loss of adipose tissue and metabolic dysfunction.Fougerat, A. ; Schoiswohl, G. ; Polizzi, A. ; Régnier, M. ; Wagner, C. ; Smati, S. ; Fougeray, T. ; Lippi, Y. ; Lasserre, F. ; Raho, I. ; Melin, V. ; Tramunt, B. ; Métivier, R. ; Sommer, C. ; Benhamed, F. ; Alkhoury, C. ; Greulich, F. ; Jouffe, C. ; Emile, A. ; Schupp, M. ; Gourdy, P. ; Dubot, P. ; Levade, T. ; Meynard, D. ; Ellero-Simatos, S. ; Gamet-Payrastre, L. ; Panasyuk, G. ; Uhlenhaut, N.H. ; Amri, E.Z. ; Cruciani-Guglielmacci, C. ; Postic, C. ; Wahli, W. ; Loiseau, N. ; Montagner, A. ; Langin, D. ; Lass, A. ; Guillou, H.
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.Sulaj, A. ; Kopf, S. ; von Rauchhaupt, E. ; Kliemank, E. ; Brune, M. ; Kender, Z. ; Bartl, H. ; Cortizo, F.G. ; Klepac, K. ; Han, Z. ; Kumar, V. ; Longo, V. ; Teleman, A.A. ; Okun, J.G. ; Morgenstern, J. ; Fleming, T. ; Szendroedi, J. ; Herzig, S. ; Nawroth, P.P.
Six-month periodic fasting in patients with type 2 diabetes and diabetic nephropathy: A proof-of-concept study.Jende, J.M.E. ; Mooshage, C. ; Kender, Z. ; Kopf, S. ; Groener, J.B. ; Heiland, S. ; Juerchott, A. ; Nawroth, P.P. ; Bendszus, M. ; Kurz, F.T.
Magnetic resonance neurography reveals smoking-associated decrease in sciatic nerve structural integrity in Type 2 diabetes.Strickland, B.A. ; Ansari, S.A. ; Dantoft, W. ; Uhlenhaut, N.H.
How to tame your genes: Mechanisms of inflammatory gene repression by glucocorticoids.Sakurai, M. ; Weber, P. ; Wolff, G. ; Wieder, A. ; Szendroedi, J. ; Herzig, S. ; Ekim Üstünel, B.
TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells.Möller, G. ; Temml, V. ; Cala Peralta, A. ; Gruet, O. ; Richomme, P. ; Séraphin, D. ; Viault, G. ; Kraus, L. ; Huber-Cantonati, P. ; Schopfhauser, E. ; Pachmayr, J. ; Tokarz, J. ; Schuster, D. ; Helesbeux, J.J. ; Dyar, K.A.
Analogues of natural chalcones as efficient inhibitors of AKR1C3.Helm, J. ; Drukewitz, S. ; Poser, I. ; Richter, S. ; Friedemann, M. ; William, D. ; Mohr, H. ; Nölting, S. ; Robledo, M. ; Bornstein, S.R. ; Eisenhofer, G. ; Bechmann, N.
Treatment of pheochromocytoma cells with recurrent cycles of hypoxia: A new pseudohypoxic in vitro model.Gehlert, S. ; Weinisch, P. ; Römisch-Margl, W. ; Jaspers, R.T. ; Artati, A. ; Adamski, J. ; Dyar, K.A. ; Aussieker, T. ; Jacko, D. ; Bloch, W. ; Wackerhage, H. ; Kastenmüller, G.
Effects of acute and chronic resistance exercise on the skeletal muscle metabolome.Jende, J.M.E. ; Kender, Z. ; Morgenstern, J. ; Renn, P. ; Mooshage, C. ; Juerchott, A. ; Kopf, S. ; Nawroth, P.P. ; Bendszus, M. ; Kurz, F.T.
Fractional anisotropy and troponin T parallel structural nerve damage at the upper extremities in a group of patients with prediabetes and type 2 diabetes - a study using 3T magnetic resonance neurography.Kotschi, S. ; Jung, A. ; Willemsen, N. ; Ofoghi, A. ; Proneth, B. ; Conrad, M. ; Bartelt, A.
NFE2L1-mediated proteasome function protects from ferroptosis.Minaskan Karabid, N. ; Wiedemann, T. ; Gulde, S. ; Mohr, H. ; Segaran Renu, C. ; Geppert, J. ; Rohm, M. ; Vitale, G. ; Gaudenzi, G. ; Dicitore, A. ; Ankerst, D.P. ; Chen, Y. ; Braren, R. ; Kaissis, G. ; Schilling, F. ; Schillmaier, M. ; Eisenhofer, G. ; Herzig, S. ; Roncaroli, F. ; Honegger, J.B. ; Pellegata, N.S.
Angpt2/Tie2 autostimulatory loop controls tumorigenesis.Jouffe, C. ; Weger, B.D. ; Martin, E. ; Atger, F. ; Weger, M. ; Gobet, C. ; Ramnath, D. ; Charpagne, A. ; Morin-Rivron, D. ; Powell, E.E. ; Sweet, M.J. ; Masoodi, M. ; Uhlenhaut, N.H. ; Gachon, F.
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.Loft, A. ; Schmidt, S.F. ; Caratti, G. ; Stifel, U. ; Havelund, J.F. ; Sekar, R. ; Kwon, Y. ; Sulaj, A. ; Chow, K.K. ; Alfaro, A.J. ; Schwarzmayr, T. ; Rittig, N. ; Svart, M. ; Tsokanos, F.-F. ; Maida, A. ; Blutke, A. ; Feuchtinger, A. ; Møller, N. ; Blüher, M. ; Nawroth, P. ; Szendrödi, J. ; Færgeman, N.J. ; Zeigerer, A. ; Tuckermann, J. ; Herzig, S.
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.Egea, V. ; Megens, R.T.A. ; Santovito, D. ; Wantha, S. ; Brandl, R. ; Siess, W. ; Khani, S. ; Soehnlein, O. ; Bartelt, A. ; Weber, C. ; Ries, C.
Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques.Bechmann, N. ; Barthel, A. ; Schedl, A. ; Herzig, S. ; Varga, Z. ; Gebhard, C. ; Mayr, M. ; Hantel, C. ; Beuschlein, F. ; Wolfrum, C. ; Perakakis, N. ; Poston, L. ; Andoniadou, C.L. ; Siow, R. ; Gainetdinov, R.R. ; Dotan, A. ; Shoenfeld, Y. ; Mingrone, G. ; Bornstein, S.R.
Sexual dimorphism in COVID-19: Potential clinical and public health implications.Worthmann, A. ; Bartelt, A.
MALDI MSI for a fresh view on atherosclerotic plaque lipids.Sato, S. ; Dyar, K.A. ; Treebak, J.T. ; Jepsen, S.L. ; Ehrlich, A.M. ; Ashcroft, S.P. ; Trost, K. ; Kunzke, T. ; Prade, V.M. ; Small, L. ; Basse, A.L. ; Schönke, M. ; Chen, S. ; Samad, M. ; Baldi, P. ; Barrès, R. ; Walch, A.K. ; Moritz, T. ; Holst, J.J. ; Lutter, D. ; Zierath, J.R. ; Sassone-Corsi, P.
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.Kornmueller,K. ; Amri, E.Z. ; Scheideler, M. ; Prassl, R.
Delivery of miRNAs to the adipose organ for metabolic health.Ha, E.E. ; Quartuccia, G.I. ; Ling, R. ; Xue, C. ; Karikari, R.A. ; Hernandez-Ono, A. ; Hu, K.Y. ; Matias, C.V. ; Imam, R. ; Cui, J. ; Pellegata, N.S. ; Herzig, S. ; Georgiadi, A. ; Soni, R.K. ; Bauer, R.C.
Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice.Geppert, J. ; Walth, A.A. ; Terron Exposito, R. ; Kaltenecker, D. ; Morigny, P. ; Machado, J. ; Becker, M. ; Simoes Fernandez, E. ; Lima, J.D.C.C. ; Daniel, C. ; Diaz, M.B. ; Herzig, S. ; Seelaender, M. ; Rohm, M.
Aging aggravates cachexia in tumor-bearing mice.Greulich, F. ; Bielefeld, K.A. ; Scheundel, R. ; Mechtidou, A. ; Strickland, B. ; Uhlenhaut, N.H.
Enhancer RNA expression in response to glucocorticoid treatment in murine macrophages.Weber, P. ; Künstner, A. ; Hess J. ; Unger, K. ; Marschner, S. ; Idel, C. ; Ribbat-Idel, J. ; Walz, C. ; Rietzler, S. ; Valeanu, L. ; Herkommer, T. ; Kreutzer, L. ; Klymenko, O. ; Kirchner, T. ; Ganswindt, U. ; Walch, A.K. ; Sterr, M. ; Lickert, H. ; Canis, M. ; Rades, D. ; Perner, S. ; Berriel Diaz, M. ; Herzig, S. ; Wollenberg, B. ; Busch, H. ; Zitzelsberger, H.
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.Morgenstern, J. ; Groener, J.B. ; Jende, J.M.E. ; Kurz, F.T. ; Strom, A. ; Göpfert, J. ; Kender, Z. ; Le Marois, M. ; Brune, M. ; Kuner, R. ; Herzig, S. ; Roden, M. ; Ziegler, D. ; Bendszus, M. ; Szendroedi, J. ; Nawroth, P.P. ; Kopf, S. ; Fleming, T.
Correction to: Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.