Group leader "Islet Facility"
PD Dr. Felicia Gerst
Fields of Work and Expertise
Beta-cell biology
Professional Background
Senior Scientist, IDM
Habilitation at the Faculty of Medicine, University of Tübingen
Postdoctoral fellow; Internal Medicine IV, University Hospital Tübingen
Postdoctoral fellow; Internal Medicine IV, University Hospital Tübingen
Doctoral Fellow, Graduate school GRK1302/2 (PI3Kinase in Diabetes and Tumor Growth) Institute of Physiology, University of Tübingen
Honors and Awards
- HUMAIN Award InSphero (Switzerland): Impact of pancreatic adipose tissue on islet function 2023
- DDG Grant: Does FFA1 alter the impact of maternal environment on postnatal maturation of beta-cells? 2021
- DZD Grant: Role of the fetal serum protein fetuin-A in the maturation of the neonatal pig islet 2018 - 2019
Publications
Sandforth, A. ; Arreola, E.V. ; Hanson, R.L. ; Wewer Albrechtsen, N.J. ; Holst, J.J. ; Ahrends, R. ; Coman, C. ; Gerst, F. ; Lorza-Gil, E. ; Cheng, Y. ; Sandforth, L. ; Katzenstein, S. ; Ganslmeier, M. ; Seissler, J. ; Hauner, H. ; Perakakis, N. ; Wagner, R. ; Machann, J. ; Schick, F. ; Peter, A. ; Lehmann, R. ; Weigert, C. ; Maurer, J. ; Preissl, H. ; Heni, M. ; Szendrödi, J. ; Kopf, S. ; Solimena, M. ; Schwarz, P. ; Blüher, M. ; Häring, H.-U. ; Hrabě de Angelis, M. ; Schürmann, A. ; Kabisch, S. ; Mai, K. ; Pfeiffer, A.F.H. ; Bornstein, S. ; Stumvoll, M. ; Roden, M. ; Stefan, N. ; Fritsche, A. ; Birkenfeld, A.L. ; Jumpertz von Schwartzenberg, R.
Prevention of type 2 diabetes through prediabetes remission without weight loss.Lorza-Gil, E. ; Strauss, O. ; Ziegler, E. ; Kansy, K. ; Katschke, M.-T. ; Rahimi, G. ; Neuscheler, D. ; Sandforth, L. ; Sandforth, A. ; Sancar, G. ; Kaufmann, B. ; Hartmann, D. ; Singer, S.R. ; Mihaljevic, A.L. ; Jumpertz von Schwartzenberg, R. ; Sbierski-Kind, J. ; Müller, T.D. ; Birkenfeld, A.L. ; Gerst, F.
Incretin-responsive human pancreatic adipose tissue organoids: A functional model for fatty pancreas research.Lorza-Gil, E. ; Kaiser, G. ; Carlein, C. ; Hoffmann, M.D.A. ; König, G.M. ; Haug, S. ; Prates Roma, L. ; Rexen Ulven, E. ; Ulven, T. ; Kostenis, E. ; Birkenfeld, A.L. ; Häring, H.U. ; Ullrich, S. ; Gerst, F.
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.Siegel-Axel, D. ; Barroso Oquendo, M. ; Gerst, F. ; Fend, F. ; Wagner, R. ; Heni, M. ; Königsrainer, A. ; Häring, H.-U. ; Fritsche, A. ; Schleicher, E. ; Birkenfeld, A.L. ; Stefan, N.
Extracellular matrix expression in human pancreatic fat cells of patients with normal glucose regulation, prediabetes and type 2 diabetes.Oquendo, M.B. ; Lorza-Gil, E. ; Juarez Lopez, D.A. ; Wagner, R. ; Birkenfeld, A.L. ; Ullrich, S. ; Gerst, F.
Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue-islet interactions.Wagner, R. ; Eckstein, S.S. ; Yamazaki, H. ; Gerst, F. ; Machann, J. ; Jaghutriz, B.A. ; Schürmann, A. ; Solimena, M. ; Singer, S.R. ; Königsrainer, A. ; Birkenfeld, A.L. ; Häring, H.-U. ; Fritsche, A. ; Ullrich, S. ; Heni, M.
Metabolic implications of pancreatic fat accumulation.Volta, F. ; Scerbo, M.J. ; Seelig, A. ; Wagner, R. ; O'Brien, N. ; Gerst, F. ; Fritsche, A. ; Häring, H.-U. ; Zeigerer, A. ; Ullrich, S. ; Gerdes, J.M.
Author Correction: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.Gerst, F. ; Kemter, E. ; Lorza-Gil, E. ; Kaiser, G. ; Fritz, A.K. ; Nano, R. ; Piemonti, L. ; Gauder, M. ; Dahl, A. ; Nadalin, S. ; Königsrainer, A. ; Fend, F. ; Birkenfeld, A.L. ; Wagner, R. ; Heni, M. ; Stefan, N. ; Wolf, E. ; Häring, H.-U. ; Ullrich, S.
The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells.Barroso Oquendo, M. ; Siegel-Axel, D.I. ; Gerst, F. ; Lorza-Gil, E. ; Moller, A. ; Wagner, R. ; Machann, J. ; Fend, F. ; Königsrainer, A. ; Heni, M. ; Häring, H.-U. ; Ullrich, S. ; Birkenfeld, A.L.
Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity.Oquendo, M.B. ; Lorza-Gil, E. ; Gerst, F. ; Fend, F. ; Koenigsrainer, A. ; Wagner, R. ; Heni, M. ; Häring, H.-U. ; Birkenfeld, A.L. ; Ullrich, S. ; Siegel-Axel, D.
Comparison between in vitro differentiation of pancreatic and subcutaneous adipocytes of subjects with normal glucose tolerance.
