Publications
Le Thuc, O. ; Noël, J. ; Rovère, C.
An ex vivo perifusion method for quantitative determination of neuropeptide release from mouse hypothalamic explants.Zhang, C.J. ; Bidlingmaier, M. ; Altaye, M. ; Page, L.C. ; D'Alessio, D. ; Tschöp, M.H. ; Tong, J.
Acute administration of acyl, but not desacyl ghrelin, decreases blood pressure in healthy humans.Kabra, U.D.
The role of mitochondrial fission protein Drp1 in pancreatic islets and beta cells.Müller, G.
Gesundheit – Vom (bio)technologischen, (eigen)verantwortlichen, fairen und realistischen Umgang.Walheim, E.
Energy deprivation induces a specific secretome in skeletal muscle.Kurz, S. ; Janas, M.K. ; Schneider, A. ; Lohr, K. ; Wettmarshausen, J. ; Perocchi, F. ; Knolle, P.A. ; Wohlleber, D.
Linking TNF receptor signaling in virus-infected hepatocytes to cell death for immune control of liver infection.Einer, C. ; Hohenester, S. ; Wimmer, R. ; Wottke, L. ; Artmann, R. ; Schulz, S. ; Gosmann, C. ; Simmons, A. ; Leitzinger, C. ; Eberhagen, C. ; Borchard, S. ; Schmitt, S. ; Hauck, S.M. ; von Toerne, C. ; Jastroch, M. ; Walheim, E. ; Rust, C. ; Gerbes, A.L. ; Popper, B. ; Mayr, D. ; Schnurr, M. ; Vollmar, A.M. ; Denk, G. ; Zischka, H.
Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks.Holze, C. ; Michaudel, C. ; Mackowiak, C. ; Haas, D.A. ; Benda, C. ; Hubel, P. ; Pennemann, F.L. ; Schnepf, D. ; Wettmarshausen, J. ; Braun, M. ; Leung, D.W. ; Amarasinghe, G.K. ; Perocchi, F. ; Staeheli, P. ; Ryffel, B. ; Pichlmair, A.
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Roveri, A. ; Peng, X. ; Freitas, F.P. ; Aichler, M. ; Jastroch, M. ; Ursini, F. ; Arner, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.Tom, R.Z. ; Gao, Y. ; Schriever, S.C. ; Lutter, D. ; Yi, C.-X. ; Tschöp, M.H. ; Hofmann, S.M.
Role of neuronal fractalkine in reducing diet-induced hypothalamic inflammation.Knerr, P.J. ; Finan, B. ; Gelfanov, V. ; Perez-Tilve, D. ; Tschöp, M.H. ; DiMarchi, R.D.
Optimization of peptide-based polyagonists for treatment of diabetes and obesity.Balsevich, G. ; Häusl, A.S. ; Meyer, C.W. ; Karamihalev, S. ; Feng, X. ; Pöhlmann, M.L. ; Dournes, C. ; Uribe-Marino, A. ; Santarelli, S. ; Labermaier, C. ; Hafner, K. ; Mao, T. ; Breitsamer, M. ; Theodoropoulou, M. ; Namendorf, C. ; Uhr, M. ; Paez-Pereda, M. ; Winter, G. ; Hausch, F. ; Chen, A. ; Tschöp, M.H. ; Rein, T. ; Gassen, N.C. ; Schmidt, M.V.
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.Polymeropoulos, E.T. ; Oelkrug, R. ; Jastroch, M.
Mitochondrial proton leak compensates for reduced oxidative power during frequent hypothermic events in a protoendothermic mammal, Echinops telfairi.Warncke, K. ; Lickert, R. ; Eitel, S. ; Gloning, K.P. ; Bonifacio, E. ; Sedlmeier, E.-M. ; Becker, P. ; Knoop, J. ; Beyerlein, A. ; Ziegler, A.-G.
Thymus growth and fetal immune responses in diabetic pregnancies.Lefort, S. ; Tschöp, M.H. ; García-Cáceres, C.
A synaptic basis for GLP-1 action in the brain.De Azua, I.R. ; Mancini, G.M. ; Srivastava, R.K. ; Rey, A.A. ; Cardinal, P. ; Tedesco, L. ; Zingaretti, C.M. ; Sassmann, A. ; Quarta, C. ; Schwitter, C. ; Conrad, A. ; Wettschureck, N. ; Vemuri, V.K. ; Makriyannis, A. ; Hartwig, J.H. ; Mendez-Lago, M. ; Bindila, L. ; Monory, K. ; Giordano, A. ; Cinti, S. ; Marsicano, G. ; Offermanns, S. ; Nisoli, E. ; Pagotto, U. ; Cota, D. ; Lutz, B.
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.Piotrowski, C. ; Lede, V. ; Butthof, A. ; Kaiser, N. ; Hirrlinger, P.G. ; Tschöp, M.H. ; Schöneberg, T. ; Bechmann, I.
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb.Lee, K.Y. ; Sharma, R. ; Gase, G. ; Ussar, S. ; Li, Y. ; Welch, L. ; Berryman, D.E. ; Kispert, A. ; Blüher, M. ; Kahn, C.R.
Tbx15 defines a glycolytic subpopulation and white adipocyte heterogeneity.Götz, A. ; Jall, S. ; Tschöp, M.H. ; Müller, T.D.
Inkretinbasierte Medikamente zur Diabetes- und Adipositastherapie. Entwicklungsperspektiven.Gaudry, M.J. ; Jastroch, M. ; Treberg, J.R. ; Hofreiter, M. ; Paijmans, J.L.A. ; Starrett, J. ; Wales, N. ; Signore, A.V. ; Springer, M.S. ; Campbell, K.L.
Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades.Duncan, L. ; Yilmaz, Z. ; Gaspar, H. ; Walters, R. ; Goldstein, J.I. ; Anttila, V. ; Bulik-Sullivan, B. ; Ripke, S. ; Thornton, L.M. ; Hinney, A. ; Daly, M. ; Sullivan, P.F. ; Zeggini, E. ; Breen, G. ; Bulik, C.M. ; Eating Disorders Working Group of the Psychiatric Genomics Consortium (Wichmann, H.-E. ; Tschöp, M.H.)
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa.Ravichandran, M. ; Grandl, G. ; Ristow, M.
Dietary carbohydrates impair healthspan and promote mortality.Gao, Y. ; Vidal-Itriago, A. ; Kalsbeek, M.J. ; Layritz, C. ; García-Cáceres, C. ; Tom, R.Z. ; Eichmann, T.O. ; Vaz, F.M. ; Houtkooper, R.H. ; van der Wel, N. ; Verhoeven, A.J. ; Yan, J. ; Kalsbeek, A. ; Eckel, R.H. ; Hofmann, S.M. ; Yi, C.X.
Lipoprotein lipase maintains microglial innate immunity in obesity.Kleinert, M. ; Clemmensen, C. ; Stemmer, K. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H.
Emerging poly-agonists for obesity and type 2 diabetes.Wiens, L. ; Banh, S. ; Sotiri, E. ; Jastroch, M. ; Block, B.A. ; Brand, M.D. ; Treberg, J.R.
Comparison of mitochondrial reactive oxygen species production of ectothermic and endothermic fish muscle.Quarta, C. ; Clemmensen, C. ; Zhu, Z. ; Yang, B. ; Joseph, S.S. ; Lutter, D. ; Yi, C.X. ; Graf, E. ; García-Cáceres, C. ; Legutko, B. ; Fischer, K. ; Brommage, R. ; Zizzari, P. ; Franklin, B.S. ; Krueger, M. ; Koch, M. ; Vettorazzi, S. ; Li, P. ; Hofmann, S.M. ; Bakhti, M. ; Bastidas-Ponce, A. ; Lickert, H. ; Strom, T.M. ; Gailus-Durner, V. ; Bechmann, I. ; Perez-Tilve, D. ; Tuckermann, J.P. ; Hrabě de Angelis, M. ; Sandoval, D.A. ; Cota, D. ; Latz, E. ; Seeley, R.J. ; Müller, T.D. ; DiMarchi, R.D. ; Finan, B. ; Tschöp, M.H.
Molecular integration of incretin and glucocorticoid action reverses immunometabolic dysfunction and obesity.Pfuhlmann, K. ; Pfluger, P.T. ; Schriever, S.C. ; Müller, T.D. ; Tschöp, M.H. ; Stemmer, K.
Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice.Wang, X. ; Haering, M.-F. ; Rathjen, T. ; Lockhart, S.M. ; Sorensen, D. ; Ussar, S. ; Rasmussen, L.M. ; Bertagnolli, M.M. ; Kahn, C.R. ; Rask-Madsen, C.
Insulin resistance in vascular endothelial cells promotes intestinal tumour formation.Kälin, S. ; Becker, M. ; Ott, V. ; Serr, I. ; Hosp, F. ; Mollah, M.M.H. ; Keipert, S. ; Lamp, D. ; Rohner-Jeanrenaud, F. ; Flynn, V.K. ; Scherm, M.G. ; Nascimento, L.F.R. ; Gerlach, K. ; Popp, V. ; Dietzen, S. ; Bopp, T. ; Krishnamurthy, P. ; Kaplan, M.H. ; Serrano, M. ; Woods, S.C. ; Tripal, P. ; Palmisano, R. ; Jastroch, M. ; Blüher, M. ; Wolfrum, C. ; Weigmann, B. ; Ziegler, A.-G. ; Mann, M. ; Tschöp, M.H. ; Daniel, C.
A Stat6/Pten axis links regulatory T cells with adipose tissue function.Böttcher, A. ; Lickert, H. ; Tschöp, M.H.
Engineering skin with skinny genes.Mayer, J.P. ; Tschöp, M.H. ; DiMarchi, R.D.
Once blind, now we see GLP-1 molecular action.Arduino, D.M. ; Wettmarshausen, J. ; Vais, H. ; Navas-Navarro, P. ; Cheng, Y. ; Leimpek, A. ; Ma, Z. ; Delrio-Lorenzo, A. ; Giordano, A. ; Garcia-Perez, C. ; Médard, G. ; Kuster, B. ; García-Sancho, J. ; Mokranjac, D. ; Foskett, J.K. ; Alonso, M.T. ; Perocchi, F.
Systematic identification of MCU modulators by orthogonal Iiterspecies chemical screening.Khajavi, N. ; Biebermann, H. ; Tschöp, M.H. ; DiMarchi, R.
Treatment of diabetes and obesity by rationally designed peptide agonists functioning at multiple metabolic receptors.Pramme-Steinwachs, I. ; Jastroch, M. ; Ussar, S.
Extracellular calcium modulates brown adipocyte differentiation and identity.Frias, J.P. ; Bastyr, E.J. ; Vignati, L. ; Tschöp, M.H. ; Schmitt, C. ; Owen, K.R. ; Christensen, R.H. ; DiMarchi, R.D.
The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes.Le Thuc, O. ; Stobbe, K. ; Cansell, C. ; Nahon, J.L. ; Blondeau, N. ; Rovère, C.
Hypothalamic inflammation and energy balance disruptions: Spotlight on chemokines.Keipert, S. ; Kutschke, M. ; Ost, M. ; Schwarzmayr, T. ; van Schothorst, E.M. ; Lamp, D. ; Brachthäuser, L. ; Hamp, I. ; Mazibuko-Mbeje, S. ; Hartwig, S. ; Lerch, S. ; Graf, E. ; Plettenburg, O. ; Neff, F. ; Tschöp, M.H. ; Jastroch, M.
Long-term cold adaptation does not require FGF21 or UCP1.Sánchez-Garrido, M.A. ; Brandt, S. ; Clemmensen, C. ; Müller, T.D. ; DiMarchi, R.D. ; Tschöp, M.H.
GLP-1/glucagon receptor co-agonism for treatment of obesity.Jastroch, M.
Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue.Fritsche, A. ; Heni, M. ; Gancheva, S. ; Preissl, H. ; Kullmann, S. ; Lehnert, H. ; Tschöp, M.H. ; Brüning, J.C. ; Roden, M. ; Häring, H.-U.
Das Gehirn als Schaltzentrale des Stoffwechsels.Gao, Y. ; Layritz, C. ; Legutko, B. ; Eichmann, T.O. ; Laperrousaz, E. ; Moullé, V.S. ; Cruciani-Guglielmacci, C. ; Magnan, C. ; Luquet, S. ; Woods, S.C. ; Eckel, R.H. ; Yi, C.-X. ; Garcia-Caceres, C. ; Tschöp, M.H.
Disruption of lipid uptake in astroglia exacerbates diet induced obesity.Hankir, M.K. ; Kranz, M. ; Keipert, S. ; Weiner, J. ; Andreasen, S.G. ; Kern, M.J. ; Patt, M. ; Kloeting, N. ; Heiker, J.T. ; Brust, P. ; Hesse, S. ; Jastroch, M. ; Fenske, W.K.
Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein 1 deficient mice.Keuper, M. ; Sachs, S. ; Walheim, E. ; Berti, L. ; Raedle, B. ; Tews, D. ; Fischer-Posovszky, P. ; Wabitsch, M. ; Hrabě de Angelis, M. ; Kastenmüller, G. ; Tschöp, M.H. ; Jastroch, M. ; Staiger, H. ; Hofmann, S.M.
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors.Rathjen, T. ; Yan, X. ; Kononenko, N.L. ; Ku, M.C. ; Song, K. ; Ferrarese, L. ; Tarallo, V. ; Puchkov, D. ; Kochlamazashvili, G. ; Brachs, S. ; Varela, L. ; Szigeti-Buck, K. ; Yi, C.-X. ; Schriever, S.C. ; Tattikota, S.G. ; Carlo, A.S. ; Moroni, M. ; Siemens, J. ; Heuser, A. ; van der Weyden, L. ; Birkenfeld, A.L. ; Niendorf, T. ; Poulet, J.F.A. ; Horvath, T.L. ; Tschöp, M.H. ; Heinig, M. ; Trajkovski, M. ; Haucke, V. ; Poy, M.N.
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.Giles, D.A. ; Moreno-Fernandez, M.E. ; Stankiewicz, T.E. ; Graspeuntner, S. ; Cappelletti, M. ; Wu, D. ; Mukherjee, R. ; Chan, C.C. ; Lawson, M.J. ; Klarquist, J. ; Sünderhauf, A. ; Softic, S. ; Kahn, C.R. ; Stemmer, K. ; Iwakura, Y. ; Aronow, B.J. ; Karns, R. ; Steinbrecher, K.A. ; Karp, C.L. ; Sheridan, R. ; Shanmukhappa, S.K. ; Reynaud, D. ; Haslam, D.B. ; Sina, C. ; Rupp, J. ; Hogan, S.P. ; Divanovic, S.
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.Tschöp, M.H. ; DiMarchi, R.
Single-molecule combinatorial therapeutics for treating obesity and diabetes.Tkatch, T. ; Greotti, E. ; Baranauskas, G. ; Pendin, D. ; Roy, S. ; Nita, L.I. ; Wettmarshausen, J. ; Prigge, M. ; Yizhar, O. ; Shirihai, O.S. ; Fishman, D. ; Hershfinkel, M. ; Fleidervish, I.A. ; Perocchi, F. ; Pozzan, T. ; Sekler, I.
Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins.Gao, Y. ; Bielohuby, M. ; Fleming, T. ; Grabner, G.F. ; Foppen, E. ; Bernhard, W. ; Guzmán-Ruiz, M. ; Layritz, C. ; Legutko, B. ; Zinser, E. ; García-Cáceres, C. ; Buijs, R.M. ; Woods, S.C. ; Kalsbeek, A. ; Seeley, R.J. ; Nawroth, P.P. ; Bidlingmaier, M. ; Tschöp, M.H. ; Yi, C.X.
Dietary sugars, not lipids, drive hypothalamic inflammation.Gruber, T. ; Garcia-Caceres, C. ; Le Thuc, O. ; Legutko, B. ; Horvath, T.L. ; Tschöp, M.H.
Hypercaloric environment triggers chronic remodeling of the hypothalamic vasculature via astroglial HIF1 alpha and VEGF signaling.Legutko, B. ; Gruber, T. ; Caceres, C.G. ; Le Thuc, O. ; Horvath, T. ; Tschöp, M.H.
Astrocytic leptin and insulin signals interact to maintain systemic metabolic homeostasis.Le Thuc, O. ; Legutko, B. ; Gruber, T. ; Li, D. ; Luquet, S. ; Tschöp, M.H. ; Garcia-Caceres, C.
Hypothalamic astrocyte activity state determines systemic glucose metabolism in mice.Caceres, C.G. ; Le Thuc, O. ; Legutko, B. ; Gruber, T. ; Jastroch, M. ; Varela, L. ; Diano, S. ; Horvath, T. ; Tschöp, M.H.
Astrocytic UCP2 is required for hypothalamic response to metabolic challenges.Dirscherl, P. ; Jastroch, M. ; Vogt-Weisenhorn, D. ; Wurst, W.
Mitochondrial function in Pink1 deficient astrocytes.Schaub, A. ; Glasmacher, E.
Splicing in immune cells - mechanistic insights and emerging topics.Kleinert, M. ; Parker, B.L. ; Fritzen, A.M. ; Knudsen, J.R. ; Jensen, T.E. ; Kjøbsted, R. ; Sylow, L. ; Ruegg, M.A. ; James, D.E. ; Richter, E.A.
Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice.Reißig, S. ; Tang, Y. ; Nikolaev, A. ; Gerlach, K. ; Wolf, C. ; Davari, K. ; Gallus, C. ; Masri, J. ; Mufazalov, I.A. ; Neurath, M.F. ; Wunderlich, F.T. ; Schattenberg, J.M. ; Galle, P.R. ; Weigmann, B. ; Waisman, A. ; Glasmacher, E. ; Hövelmeyer, N.
Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.Davari, K. ; Lichti, J. ; Gallus, C. ; Greulich, F. ; Uhlenhaut, N.H. ; Heinig, M. ; Friedel, C.C. ; Glasmacher, E.
Rapid genome-wide recruitment of RNA polymerase II drives transcription, splicing, and translation events during T cell responses.Collden, G. ; Tschöp, M.H. ; Müller, T.D.
Therapeutic potential of targeting the ghrelin pathway.Nathan, S.R. ; Pino, N.W. ; Arduino, D.M. ; Perocchi, F. ; MacMillan, S.N. ; Wilson, J.J.N.
Synthetic methods for the preparation of a functional analogue of Ru360, a potent inhibitor of mitochondrial calcium uptake.Ussar, S. ; Haering, M.-F. ; Fujisaka, S. ; Lutter, D. ; Lee, K.Y. ; Li, N. ; Gerber, G.K. ; Bry, L. ; Kahn, C.R.
Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor.Schriever, S.C. ; Zimprich, A. ; Pfuhlmann, K. ; Baumann, P. ; Giesert, F. ; Klaus, V. ; Kabra, D. ; Hafen, U. ; Romanov, A. ; Tschöp, M.H. ; Wurst, W. ; Conrad, M. ; Hölter, S.M. ; Weisenhorn, D.M. ; Pfluger, P.T.
Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.Klaus, V. ; Bastek, H. ; Damme, K. ; Collins, L.B. ; Frötschl, R. ; Benda, N. ; Lutter, D. ; Ellinger-Ziegelbauer, H. ; Swenberg, J.A. ; Dietrich, D.R. ; Stemmer, K.
Time-matched analysis of DNA adduct formationand early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.Varela, L. ; Suyama, S. ; Huang, Y. ; Shanabrough, M. ; Tschöp, M.H. ; Gao, X.B. ; Giodano, F.J. ; Horvath, T.L.
Endothelial HIF-1α enables hypothalamic glucose uptake to drive POMC neurons.Aichler, M. ; Borgmann, D.M. ; Krumsiek, J. ; Buck, A. ; MacDonald, P.E. ; Fox, J.E.M. ; Lyon, J. ; Light, P.E. ; Keipert, S. ; Jastroch, M. ; Feuchtinger, A. ; Müller, N.S. ; Sun, N. ; Palmer, A. ; Alexandrov, T. ; Hrabě de Angelis, M. ; Neschen, S. ; Tschöp, M.H. ; Walch, A.K.
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.Fuchs, Y.F. ; Eugster, A. ; Dietz, S. ; Sebelefsky, C. ; Kühn, D. ; Wilhelm, C. ; Lindner, A. ; Gavrisan, A. ; Knoop, J. ; Dahl, A. ; Ziegler, A.-G. ; Bonifacio, E.
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.Le Thuc, O. ; Rovère, C.
[Hypothalamic inflammation and energy balance deregulations: Focus on chemokines.].Laperrousaz, E. ; Moullé, V.S. ; Denis, R.G. ; Kassis, N. ; Berland, C. ; Colsch, B. ; Fioramonti, X. ; Philippe, E. ; Lacombe, A. ; Vanacker, C. ; Butin, N. ; Bruce, K.D. ; Wang, H. ; Wang, Y. ; Gao, Y. ; García-Cáceres, C. ; Prévot, V. ; Tschöp, M.H. ; Eckel, R.H. ; Le Stunff, H. ; Luquet, S. ; Magnan, C. ; Cruciani-Guglielmacci, C.
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.Müller, T.D. ; Finan, B. ; Clemmensen, C. ; DiMarchi, R.D. ; Tschöp, M.H.
The new biology and pharmacology of glucagon.Honrath, B. ; Matschke, L. ; Meyer, T. ; Magerhans, L. ; Perocchi, F. ; Ganjam, G.K. ; Zischka, H. ; Krasel, C. ; Gerding, A. ; Bakker, B.M. ; Bünemann, M. ; Strack, S. ; Decher, N. ; Culmsee, C. ; Dolga, A.M.
SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.Wettmarshausen, J. ; Perocchi, F.
Isolation of functional mitochondria from cultured cells and mouse tissues.Kabra, U.D. ; Pfuhlmann, K. ; Migliorini, A. ; Keipert, S. ; Lamp, D. ; Korsgren, O. ; Gegg, M. ; Woods, S.C. ; Pfluger, P.T. ; Lickert, H. ; Affourtit, C. ; Tschöp, M.H. ; Jastroch, M.
Direct substrate delivery into mitochondrial-fission deficient pancreatic islets rescues insulin secretion.Jastroch, M. ; Tschöp, M.H.
METABOLISM. Fat controls U. Circulating uridine acts as a hunger signal.Sylow, L. ; Kleinert, M. ; Richter, E.A. ; Jensen, T.E.
Exercise-stimulated glucose uptake - regulation and implications for glycaemic control.Kahn, C.R. ; Ussar, S.
Response to comment on Ussar et al. Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor. Diabetes 2017;66:886-896.Yi, C.-X. ; Walter, M.C. ; Gao, Y. ; Pitra, S. ; Legutko, B. ; Kälin, S. ; Layritz, C. ; García-Cáceres, C. ; Bielohuby, M. ; Bidlingmaier, M. ; Woods, S.C. ; Ghanem, A. ; Conzelmann, K.K. ; Stern, J.E. ; Jastroch, M. ; Tschöp, M.H.
TNFα drives mitochondrial stress in POMC neurons in obesity.Clemmensen, C. ; Müller, T.D. ; Woods, S.C. ; Berthoud, H.R. ; Seeley, R.J. ; Tschöp, M.H.
Gut-brain cross-talk in metabolic control.Jall, S. ; Sachs, S. ; Clemmensen, C. ; Finan, B. ; Neff, F. ; DiMarchi, R.D. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice.Hinney, A. ; Kesselmeier, M. ; Jall, S. ; Volckmar, A.L. ; Föcker, M. ; Antel, J. ; Heid, I.M. ; Winkler, T.W. ; Grant, S.F.A. ; Guo, Y. ; Bergen, A.W. ; Kaye, W. ; Berrettini, W. ; Hakonarson, H. ; Herpertz-Dahlmann, B. ; de Zwaan, M. ; Herzog, W. ; Ehrlich, S. ; Zipfel, S. ; Egberts, K.M. ; Adan, R.A. ; Brandys, M.K. ; van Elburg, A.A. ; Perica, V.B. ; Franklin, C.S. ; Tschop, M.H. ; Zeggini, E. ; Bulik, C.M. ; Collier, D.A. ; Scherag, A. ; Müller, T.D. ; Hebebrand, J.
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index (vol 22, pg 192, 2017).Fischer, K. ; Ruiz, H.H. ; Jhun, K. ; Finan, B. ; Oberlin, D.J. ; van der Heide, V. ; Kalinovich, A.V. ; Petrovic, N. ; Wolf, Y. ; Clemmensen, C. ; Shin, A.C. ; Divanovic, S. ; Brombacher, F. ; Glasmacher, E. ; Keipert, S. ; Jastroch, M. ; Nagler, J. ; Schramm, K.-W. ; Medrikova, D. ; Collden, G. ; Woods, S.C. ; Herzig, S. ; Homann, D. ; Jung, S. ; Nedergaard, J. ; Cannon, B. ; Tschöp, M.H. ; Müller, T.D. ; Buettner, C.
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis.Polymeropoulos, E.T. ; Oelkrug, R. ; White, C.R. ; Jastroch, M.
Phylogenetic analysis of the allometry of metabolic rate and mitochondrial basal proton leak.Al Massadi, O. ; López, M. ; Tschöp, M.H. ; Dieguez, C. ; Nogueiras, R.
Current understanding of the hypothalamic ghrelin pathways inducing appetite and adiposity.Heninger, A.K. ; Jergens, S. ; Wilhelm, C. ; Beyerlein, A. ; Ziegler, A.-G. ; Bonifacio, E.
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.Clemmensen, C. ; Jørgensen, C.V. ; Smajilovic, S. ; Bräuner-Osborne, H.
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor.Ost, M. ; Keipert, S. ; Klaus, S.
Targeted mitochondrial uncoupling beyond UCP1 - The fine line between death and metabolic health.Hinney, A. ; Kesselmeier, M. ; Jall, S. ; Volckmar, A.L. ; Föcker, M. ; Antel, J. ; Genetic Consortium for Anorexia Nervosa (GCAN) () ; Wellcome Trust Case Control Consortium 3 (WTCCC3) () ; Heid, I.M. ; Winkler, T.W. ; GIANT Consortium (Collier, D.A. ; Gieger, C. ; Müller, T.D. ; Illig, T. ; Scherag, A. ; Hebebrand, J. ; Thorand, B. ; Wichmann, H.-E.) ; Grant, S.F. ; Early Growth Genetics Consortium () ; Guo, Y. ; Bergen, A.W. ; Kaye, W. ; Berrettini, W. ; Hakonarson, H. ; Price Foundation Collaborative Group () ; Children's Hospital of Philadelphia/Price Foundation () ; Herpertz-Dahlmann, B. ; de Zwaan, M. ; Herzog, W. ; Ehrlich, S. ; Zipfel, S. ; Egberts, K.M. ; Adan, R.A. ; Brandys, M.K. ; van Elburg, A.A. ; Boraska Perica, V. ; Franklin, C.S. ; Tschöp, M.H.
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.