Publications
von Gamm, M.
Myeloid cells require the ribonuclease Regnase-3 for immune homeostasis and balanced interferon responses in vivo.Willmann, C. ; Brockmann, K. ; Wagner, R. ; Kullmann, S. ; Heni, M. ; Schnauder, G. ; Maetzler, W. ; Gasser, T. ; Berg, D. ; Eschweiler, G.W. ; Metzger, F. ; Fallgatter, A.J. ; Häring, H.-U. ; Fritsche, A.
Insulin sensitivity predicts cognitive decline in individuals with prediabetes.Kullmann, S. ; Abbas, Z. ; Machann, J. ; Scheffler, K. ; Birkenfeld, A.L. ; Häring, H.-U. ; Fritsche, A. ; Heni, M.
Investigating obesity-associated brain inflammation using quantitative water content mapping.Lampl, S. ; Janas, M.K. ; Donakonda, S. ; Brugger, M. ; Lohr, K. ; Schneider, A. ; Manske, K. ; Sperl, L.E. ; Kläger, S. ; Küster, B. ; Wettmarshausen, J. ; Müller, C. ; Laschinger, M. ; Hartmann, D. ; Hüser, N. ; Perocchi, F. ; Schmitt-Kopplin, P. ; Hagn, F. ; Zender, L. ; Hornung, V. ; Borner, C. ; Pichlmair, A. ; Kashkar, H. ; Klingenspor, M. ; Prinz, M. ; Schreiner, S. ; Conrad, M. ; Jost, P.J. ; Zischka, H. ; Steiger, K. ; Krönke, M. ; Zehn, D. ; Protzer, U. ; Heikenwälder, M. ; Knolle, P.A. ; Wohlleber, D.
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.Meissner, K. ; Lutter, D. ; von Toerne, C. ; Haile, A. ; Woods, S.C. ; Hoffmann, V. ; Ohmayer, U. ; Hauck, S.M. ; Tschöp, M.H.
Molecular classification of the placebo effect in nausea.Klymenko, O. ; Brecklinghaus, T. ; Dille, M. ; Springer, C. ; de Wendt, C. ; Altenhofen, D. ; Binsch, C. ; Knebel, B. ; Scheller, J. ; Hardt, C. ; Herwig, R. ; Chadt, A. ; Pfluger, P.T. ; Al-Hasani, H. ; Kabra, D.G.
Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle.Schleger, F. ; Fritsche, L. ; Birkenfeld, A.L. ; Heni, M. ; Fritsche, A.
Materner Metabolismus und fetale Entwicklung.Pittis, A.A. ; Goh, V. ; Cebrian Serrano, A. ; Wettmarshausen, J. ; Perocchi, F. ; Gabaldón, T.
Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter.Schwerbel, K. ; Kamitz, A. ; Krahmer, N. ; Hallahan, N. ; Jähnert, M. ; Gottmann, P. ; Lebek, S. ; Schallschmidt, T. ; Arends, D. ; Schumacher, F. ; Kleuser, B. ; Haltenhof, T. ; Heyd, F. ; Gancheva, S. ; Broman, K.W. ; Roden, M. ; Joost, H.G. ; Chadt, A. ; Al-Hasani, H. ; Vogel, H. ; Jonas, W. ; Schürmann, A.
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.Cinque, L. ; De Leonibus, C. ; Iavazzo, M. ; Krahmer, N. ; Intartaglia, D. ; Salierno, F.G. ; De Cegli, R. ; Di Malta, C. ; Svelto, M. ; Lanzara, C. ; Maddaluno, M. ; Wanderlingh, L.G. ; Huebner, A.K. ; Cesana, M. ; Bonn, F. ; Polishchuk, E. ; Hübner, C.A. ; Conte, I. ; Dikic, I. ; Mann, M. ; Ballabio, A. ; Sacco, F. ; Grumati, P. ; Settembre, C.
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.Kleinert, M. ; Müller, T.D.
A new FGF21 analog for the treatment of fatty liver disease.Müller, G. ; Ussar, S. ; Tschöp, M.H. ; Müller, T.D.
Age-dependent membrane release and degradation of full-length glycosylphosphatidylinositol-anchored proteins in rats.Meul, T. ; Berschneider, K. ; Schmitt, S. ; Mayr, C. ; Mattner, L. ; Schiller, H. B. ; Yazgili, A.S. ; Wang, X. ; Lukas, C. ; Schlesser, C. ; Prehn, C. ; Adamski, J. ; Graf, E. ; Schwarzmayr, T. ; Perocchi, F. ; Kukat, A. ; Trifunovic, A. ; Kremer, L.S. ; Prokisch, H. ; Popper, B. ; von Toerne, C. ; Hauck, S.M. ; Zischka, H. ; Meiners, S.
Mitochondrial regulation of the 26S proteasome.Ladwig, K.-H. ; Schriever, S.C. ; Atasoy, S. ; Bidlingmaier, M. ; Kruse, J. ; Johar, H.
Association of generalized and central obesity with serum and salivary cortisol secretion patterns in the elderly: Findings from the cross sectional KORA-Age study.Blutke, A. ; Sun, N. ; Xu, Z. ; Buck, A. ; Harrison, L. ; Schriever, S.C. ; Pfluger, P.T. ; Wiles, D. ; Kunzke, T. ; Huber, K. ; Schlegel, J. ; Aichler, M. ; Feuchtinger, A. ; Matiasek, K. ; Hauck, S.M. ; Walch, A.K.
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.Onogi, Y. ; Khalil, A. ; Ussar, S.
Identification and characterization of adipose surface epitopes.Schriever, S.C. ; Kabra, D.G. ; Pfuhlmann, K. ; Baumann, P. ; Baumgart, E.V. ; Nagler, J. ; Seebacher, F. ; Harrison, L. ; Irmler, M. ; Kullmann, S. ; Corrêa-da-Silva, F. ; Giesert, F. ; Jain, R. ; Schug, H. ; Castel, J. ; Martinez, S. ; Wu, M. ; Häring, H.-U. ; Hrabě de Angelis, M. ; Beckers, J. ; Müller, T.D. ; Stemmer, K. ; Wurst, W. ; Rozman, J. ; Nogueiras, R. ; de Angelis, M. ; Molkentin, J.D. ; Krahmer, N. ; Yi, C.-X. ; Schmidt, M.V. ; Luquet, S. ; Heni, M. ; Tschöp, M.H. ; Pfluger, P.T.
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.Simon, J.J. ; Stopyra, M.A. ; Mönning, E. ; Sailer, S. ; Lavandier, N. ; Kihm, L.P. ; Bendszus, M. ; Preissl, H. ; Herzog, W. ; Friederich, H.C.
Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity.Escoter Torres, L. ; Greulich, F. ; Quagliarini, F. ; Wierer, M. ; Uhlenhaut, N.H.
Anti-inflammatory functions of the glucocorticoid receptor require DNA binding.Stemmer, K. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Müller, T.D.
Insights into incretin-based therapies for treatment of diabetic dyslipidemia.Hampe, C.S. ; Sahabandu, D. ; Kaiser, V. ; Telieps, T. ; Smeeth, L. ; Agyemang, C. ; Spranger, J. ; Schulze, M.B. ; Mockenhaupt, F.P. ; Danquah, I. ; Rolandsson, O.
Geographic location determines beta-cell autoimmunity among adult Ghanaians: Findings from the RODAM study.Elgebaly, H. ; Germoush, M. ; Mosa, N. ; Zahou, F. ; Soffar, A. ; Alotaibi, N. ; Qarmush, M. ; Hussein, O. ; Bin-Jumah, M. ; Hassanein, E. ; Hernandez-Bautista, R. ; Mahmoud, A.M.
Adenium obesum flowers extract mitigates testicular injury and oxidative stress in streptozotocin-induced diabetic rats.Abukhalil, M.H. ; Hussein, O.E. ; Bin-Jumah, M. ; Saghir, S.A.M. ; Germoush, M.O. ; Elgebaly, H.A. ; Mosa, N.M. ; Hamad, I. ; Qarmush, M.M. ; Hassanein, E.M. ; Kamel, E.M. ; Hernandez-Bautista, R. ; Mahmoud, A.M.
Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats.Seebacher, F. ; Zeigerer, A. ; Kory, N. ; Krahmer, N.
Hepatic lipid droplet homeostasis and fatty liver disease.Fritzen, A.M. ; Domingo-Espín, J. ; Lundsgaard, A.M. ; Kleinert, M. ; Israelsen, I. ; Carl, C.S. ; Nicolaisen, T.S. ; Kjøbsted, R. ; Jeppesen, J.F. ; Wojtaszewski, J.F.P. ; Lagerstedt, J.O. ; Kiens, B.
ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2.Fischer, K. ; Fenzl, A. ; Liu, D. ; Dyar, K.A. ; Kleinert, M. ; Brielmeier, M. ; Clemmensen, C. ; Fedl, A. ; Finan, B. ; Gessner, A. ; Jastroch, M. ; Huang, J. ; Keipert, S. ; Klingenspor, M. ; Brüning, J.C. ; Kneilling, M. ; Maier, F.C. ; Othman, A.E. ; Pichler, B.J. ; Pramme-Steinwachs, I. ; Sachs, S. ; Scheideler, A. ; Thaiss, W.M. ; Uhlenhaut, N.H. ; Ussar, S. ; Woods, S.C. ; Zorn, J. ; Stemmer, K. ; Collins, S. ; Diaz-Meco, M. ; Moscat, J. ; Tschöp, M.H. ; Müller, T.D.
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.Sachs, S. ; Bastidas-Ponce, A. ; Tritschler, S. ; Bakhti, M. ; Böttcher, A. ; Sánchez-Garrido, M.A. ; Tarquis Medina, M. ; Kleinert, M. ; Fischer, K. ; Jall, S. ; Harger, A. ; Bader, E. ; Roscioni, S. ; Ussar, S. ; Feuchtinger, A. ; Yesildag, B. ; Neelakandhan, A. ; Jensen, C.B. ; Cornu, M. ; Yang, B. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Theis, F.J. ; Hofmann, S.M. ; Müller, T.D. ; Lickert, H.
Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission (Nature Metabolism, (2020), 2, 2, (192-209), 10.1038/s42255-020-0171-3).Berland, C. ; Montalban, E. ; Perrin, E. ; Di Miceli, M. ; Nakamura, Y. ; Martinat, M. ; Sullivan, M. ; Davis, X.S. ; Shenasa, M.A. ; Martin, C. ; Tolu, S. ; Marti, F. ; Caille, S. ; Castel, J. ; Perez, S. ; Salinas, C.G. ; Morel, C. ; Hecksher-Sørensen, J. ; Cador, M. ; Fioramonti, X. ; Tschöp, M.H. ; Layé, S. ; Venance, L. ; Faure, P. ; Hnasko, T.S. ; Small, D.M. ; Gangarossa, G. ; Luquet, S.H.
Circulating triglycerides gate dopamine-associated behaviors through DRD2-expressing neurons.de Angelis, M. ; Schriever, S.C. ; Kyriakou, E. ; Sattler, M. ; Messias, A.C. ; Schramm, K.-W. ; Pfluger, P.T.
Detection and quantification of the anti-obesity drug celastrol in murine liver and brain.Plaza-Díaz, J. ; Pastor-Villaescusa, B. ; Rueda-Robles, A. ; Abadia-Molina, F. ; Ruiz Ojeda, F.J.
Plausible biological interactions of low- and non-calorie sweeteners with the intestinal microbiota: An update of recent studies.Krude, H. ; Biebermann, H. ; Schuelke, M. ; Müller, T.D. ; Tschöp, M.H.
Allan-herndon-dudley-syndrome: Considerations about the brain phenotype with implications for treatment strategies.Jastroch, M. ; Ussar, S. ; Keipert, S.
Gut microbes controlling blood sugar: No fire required!Jall, S. ; de Angelis, M. ; Lundsgaard, A.M. ; Fritzen, A.M. ; Nicolaisen, T.S. ; Klein, A.B. ; Novikoff, A. ; Sachs, S. ; Richter, E.A. ; Kiens, B. ; Schramm, K.-W. ; Tschöp, M.H. ; Stemmer, K. ; Clemmensen, C. ; Müller, T.D. ; Kleinert, M.
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity.Ziegler, A.-G. ; Kick, K. ; Bonifacio, E. ; Haupt, F. ; Hippich, M. ; Dunstheimer, D. ; Lang, M. ; Laub, O. ; Warncke, K. ; Lange, K. ; Assfalg, R. ; Jolink, M. ; Winkler, C. ; Achenbach, P.
Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany.Müller, G. ; Herling, A.W. ; Wied, S. ; Müller, T.D.
CB1 receptor-dependent and independent induction of lipolysis in primary rat adipocytes by the inverse agonist rimonabant (SR141716A).Sander, P. ; Arduino, D.M. ; Wilting, F. ; Schweitzer, M. ; Gudermann, T. ; Perocchi, F. ; Schredelseker, J.
Novel mitochondrial Ca2+ enhancers for the treatment of cardiac arrhythmia.Müller, G. ; Tschöp, M.H. ; Müller, T.D.
Upregulated phospholipase D activity toward glycosylphosphatidylinositol-anchored proteins in micelle-like serum complexes in metabolically deranged rats and humans.Müller, T.D. ; Habegger, K.
Revisiting the pharmacological value of glucagon: An editorial for the special Issue "The biology and pharmacology of glucagon".Knoop, J. ; Eugster, A. ; Gavrisan, A. ; Lickert, R. ; Sedlmeier, E.-M. ; Dietz, S. ; Lindner, A. ; Warncke, K. ; Hummel, N. ; Ziegler, A.-G. ; Bonifacio, E.
Maternal type 1 diabetes reduces autoantigen-responsive CD4(+) T cells in Offspring.Sachs, S. ; Bastidas-Ponce, A. ; Tritschler, S. ; Bakhti, M. ; Böttcher, A. ; Sánchez-Garrido, M.A. ; Tarquis Medina, M. ; Kleinert, M. ; Fischer, K. ; Jall, S. ; Harger, A. ; Bader, E. ; Roscioni, S. ; Ussar, S. ; Feuchtinger, A. ; Yesildag, B. ; Neelakandhan, A. ; Jensen, C.B. ; Cornu, M. ; Yang, B. ; Finan, B. ; DiMarchi, R.D. ; Tschöp, M.H. ; Theis, F.J. ; Hofmann, S.M. ; Müller, T.D. ; Lickert, H.
Targeted pharmacological therapy restores β-cell function for diabetes remission.Keipert, S. ; Lutter, D. ; Schroeder, B.O. ; Brandt, D. ; Ståhlman, M. ; Schwarzmayr, T. ; Graf, E. ; Fuchs, H. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Rozman, J. ; Jastroch, M.
Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice.Gonzales García, I. ; Milbank, E. ; Martinez-Ordoñez, A. ; Diéguez, C. ; López, M. ; Contreras, C.
HYPOTHesizing about central comBAT against obesity.Tan, Q. ; Orsso, C.E. ; Deehan, E.C. ; Triador, L. ; Field, C.J. ; Tun, H.M. ; Han, J.C. ; Müller, T.D. ; Haqq, A.M.
Current and emerging therapies for managing hyperphagia and obesity in Prader-Willi syndrome: A narrative review.Lundsgaard, A.M. ; Fritzen, A.M. ; Nicolaisen, T.S. ; Carl, C.S. ; Sjøberg, K.A. ; Raun, S.H. ; Klein, A.B. ; Sánchez Quant, E.S. ; Langer, J. ; Ørskov, C. ; Clemmensen, C. ; Tschöp, M.H. ; Richter, E.A. ; Kiens, B. ; Kleinert, M.
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation.Knerr, P.J. ; Mowery, S.A. ; Finan, B. ; Perez-Tilve, D. ; Tschöp, M.H. ; DiMarchi, R.D.
Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates.Naranjo, V. ; Contreras, A. ; Merino, B. ; Plaza, A. ; Lorenzo, M.P. ; García-Cáceres, C. ; García, A. ; Chowen, J.A. ; Ruiz-Gayo, M. ; Del Olmo, N. ; Cano, V.
Specific deletion of the astrocyte leptin receptor induces changes in hippocampus glutamate metabolism, synaptic transmission and plasticity.Knudsen, J.R. ; Fritzen, A.M. ; James, D.E. ; Jensen, T.E. ; Kleinert, M. ; Richter, E.A.
Growth factor-dependent and -independent activation of mTORC2.Müller, G.
Membrane insertion and intercellular transfer of glycosylphosphatidylinositol-anchored proteins: potential therapeutic applications.