Teperino Lab
Environmental Epigenetics
About our Group
Diabetes and Obesity affect almost 400 million people worldwide and forecasts anticipate an increase of at least 20% by 2030.
Epidemiological studies have shown a high degree of genetic predisposition and familial aggregation in both diabetes and obesity. Nevertheless, lifestyle interventions have proven valuable in disease prevention and management.
Our group of Environmental Epigenetics focuses on the interface between metabolism, genetics and disease. We study physiological and pathological aspects of gene-environment interaction and epigenetic control of inheritance and aim to find novel targets and/or mechanisms towards effective strategies for disease prevention.
Publications
Aljabali, S. M. ; Pai, S. ; Teperino, R.
Paternal impact on the developmental programming of sexual dimorphism.Trigg, N. ; Schjenken, J.E. ; Martin, J.H. ; Skerrett-Byrne, D.A. ; Smyth, S.P. ; Bernstein, I.R. ; Anderson, A.L. ; Stanger, S.J. ; Simpson, E.N.A. ; Tomar, A. ; Teperino, R. ; Conine, C.C. ; De Iuliis, G.N. ; Roman, S.D. ; Bromfield, E.G. ; Dun, M.D. ; Eamens, A.L. ; Nixon, B.
Subchronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice.Skerrett-Byrne, D.A. ; Teperino, R. ; Nixon, B.
ShinySperm: Navigating the sperm proteome landscape.Schäfer, F. ; Tomar, A. ; Sato, S. ; Teperino, R. ; Imhof, A. ; Lahiri, S.
Enhanced in situ spatial proteomics by effective combination of MALDI imaging and LC-MS/MS.Tomar, A. ; Gómez Velázquez, M. ; Gerlini, R. ; Comas-Armangue, G. ; Makharadze, L. ; Kolbe, T. ; Boersma, A. ; Dahlhoff, M. ; Burgstaller, J.P. ; Lassi, M. ; Darr, J. ; Toppari, J. ; Virtanen, H. ; Kühnapfel, A. ; Scholz, M. ; Landgraf, K. ; Kiess, W. ; Vogel, M. ; Gailus-Durner, V. ; Fuchs, H. ; Marschall, S. ; Hrabě de Angelis, M. ; Kotaja, N. ; Körner, A. ; Teperino, R.
Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs.