Publications
Almendros, I. ; Bartel, S. ; Bostantzoglou, C. ; Jubrail, J. ; Lehmann, M. ; Wagner, D.E.
Early career members at the ers lsc 2017: Mechanistic overlap between chronic lung injury and cancer.Maldonado, M. ; Salgado-Aguayo, A. ; Herrera, I. ; Ortiz, B. ; Staab-Weijnitz, C.A. ; Selman, M. ; Pardo, A.
MMP28 is overexpressed in bronchial and alveolar epithelial cells in Idiopathic Pulmonary Fibrosis.Giopanou, I. ; Lilis, I. ; Papadaki, H. ; Papadas, T. ; Stathopoulos, G.T.
A link between ReIB expression and tumor progression in laryngeal cancer.Hellbach, K. ; Yaroshenko, A. ; Willer, K. ; Conlon, T.M. ; Braunagel, M.B. ; Auweter, S. ; Yildirim, A.Ö. ; Eickelberg, O. ; Pfeiffer, F. ; Reiser, M.F. ; Meinel, F.G.
X-ray dark-field radiography facilitates the diagnosis of pulmonary fibrosis in a mouse model.Ding, Y. ; Wohlleben, W. ; Boland, M. ; Vilsmeier, K. ; Riediker, M.
Nano-object release during machining of polymer-based manocomposites depends on process factors and the type of nanofiller.Schmid, O. ; Jud, C. ; Umehara, Y. ; Mueller, D. ; Bucholski, A. ; Gruber, F. ; Denk, O. ; Egle, R. ; Petri-Fink, A. ; Rothen-Rutishauser, B.M.
Biokinetics of aerosolized liposomal ciclosporin A in human lung cells in vitro using an air-liquid cell interface exposure system.Spadaro, M. ; Winklmeier, S. ; Beltran, E. ; Macrini, C. ; Hoeftberger, R. ; Schuh, E. ; Thaler, F.S. ; Gerdes, L.A. ; Laurent, S.A. ; Gerhards, R. ; Braendle, S. ; Dornmair, K. ; Moser, M. ; Krishnamoorthy, G. ; Kamp, F. ; Jenne, D. ; Hohlfeld, R. ; Kmpfel, T. ; Lassmann, H. ; Kawakami, N. ; Meinl, E.
Pathogenic mechanisms of human autoantibodies against myelin oligodendrocyte glycoprotein.Schmid, O. ; Cassee, F.R.
On the pivotal role of dose for particle toxicology and risk assessment: exposure is a poor surrogate for delivered dose.Voigt, C. ; May, P. ; Gottschlich, A. ; Markota, A. ; Wenk, D. ; Gerlach, I. ; Voigt, S. ; Stathopoulos, G.T. ; Arendt, K.A.M. ; Heise, C. ; Rataj, F. ; Janssen, K.P. ; Königshoff, M. ; Winter, H. ; Himsl, I. ; Thasler, W.E. ; Schnurr, M. ; Rothenfußer, S. ; Endres, S. ; Kobold, S.
Cancer cells induce interleukin-22 production from memory CD4+T cells via interleukin-1 to promote tumor growth.Brandsma, C.A. ; de Vries, M. ; Costa, R. ; Woldhuis, R.R. ; Königshoff, M. ; Timens, W.
Lung ageing and COPD: Is there a role for ageing in abnormal tissue repair?Ryerson, C.J. ; Corte, T.J. ; Lee, J.S. ; Richeldi, L. ; Walsh, S.L.F. ; Myers, J.L. ; Behr, J. ; Cottin, V. ; Danoff, S.K. ; Flaherty, K.R. ; Lederer, D.J. ; Lynch, D.A. ; Martinez, F.J. ; Raghu, G. ; Travis, W.D. ; Udwadia, Z. ; Wells, A.U. ; Collard, H.R.
A standardized diagnostic ontology for fibrotic interstitial lung disease. An International Working Group Perspective.Oak, P. ; Hilgendorff, A.
The BPD trio? Interaction of dysregulated PDGF, VEGF, and TGF signaling in neonatal chronic lung disease.Egaña, I. ; Kaito, H. ; Nitzsche, A. ; Becker, L. ; Ballester-Lopez, C. ; Niaudet, C. ; Petkova, M. ; Liu, W. ; Vandlandewijck, M. ; Vernaleken, A. ; Klopstock, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rask-Andersen, H. ; Johansson, H.J. ; Lehtiö, J. ; He, L. ; Yildirim, A.Ö. ; Hellström, M. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Ollert, M. ; Schmidt-Weber, C.B. ; Amarie, O.V. ; Graw, J. ; Beckers, J. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Moreth, K. ; Bekeredjian, R. ; Neff, F. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Rozman, J. ; Klingenspor, M. ; Stöger, T. ; Eickelberg, O. ; Treise, I. ; Busch, D.H. ; Östereicher, M.A. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S.)
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.Tacke, U. ; Weigand-Brunnhölzl, H. ; Hilgendorff, A. ; Giese, R.M. ; Flemmer, A.W. ; König, H. ; Warken-Madelung, B. ; Arens, M. ; Hesse, N. ; Schroeder, A.S.
Entwicklungsneurologie – vernetzte Medizin und neue Perspektiven.Bowl, M.R. ; Simon, M.M. ; Ingham, N.J. ; Greenaway, S. ; Santos, L. ; Cater, H. ; Taylor, S. ; Mason, J. ; Kurbatova, N. ; Pearson, S. ; Bower, L.R. ; Clary, D. ; Meziane, H. ; Reilly, P. ; Minowa, O. ; Kelsey, L. ; Tocchini-Valentini, G.P. ; Gao, X. ; Bradley, A. ; Skarnes, W.C. ; Moore, M. ; Beaudet, A.L. ; Justice, M.J. ; Seavitt, J.R. ; Dickinson, M.E. ; Wurst, W. ; Hrabě de Angelis, M. ; Herault, Y. ; Wakana, S. ; Nutter, L.M.J. ; Flenniken, A.M. ; McKerlie, C. ; Murray, S.A. ; Svenson, K.L. ; Braun, R.E. ; West, D.B. ; Llyod, K.C.K. ; Adams, D.J. ; White, J. ; Karp, N. ; Flicek, P. ; Smedley, D. ; Meehan, T.F. ; Parkinson, H.E. ; Teboul, L. ; Wells, S. ; Steel, K.P. ; Mallon, A.M. ; Brown, S.D. ; International Mouse Phenotyping Consortium (Beig, J. ; Bürger, A. ; Giesert, F. ; Graw, J. ; Kühn, R. ; Oritz, O. ; Schick, J. ; Seisenberger, C. ; Amarie, O.V. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Aguilar-Pimentel, J.A. ; Beckers, J. ; Brommage, R. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Marschall, S. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Treise, I. ; Stöger, T. ; Yildirim, A.Ö. ; Becker, L. ; Rathkolb, B. ; Eickelberg, O. ; Schmidt-Weber, C.B.)
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Mümmler, C. ; Burgy, O. ; Hermann, S. ; Mutze, K. ; Günther, A. ; Königshoff, M.
Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis.Fuchs, H. ; Aguilar-Pimentel, A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Cho, Y.-L. ; Garrett, L. ; Hölter, S.M. ; Irmler, M. ; Kistler, M. ; Kraiger, M. ; Mayer-Kuckuk, P. ; Moreth, K. ; Rathkolb, B. ; Rozman, J. ; da Silva Buttkus, P. ; Treise, I. ; Zimprich, A. ; Gampe, K. ; Hutterer, C. ; Leuchtenberger, S. ; Maier, H. ; Miller, M. ; Scheideler, A. ; Wu, M. ; Beckers, J. ; Bekeredjian, R. ; Brielmeier, M. ; Busch, D.H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Schmidt-Weber, C.B. ; Stöger, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.Schmid, O. ; Stöger, T.
Corrigendum to “Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung” [Journal of Aerosol Science 99 (2016) 133–143](S0021850215301166)(10.1016/j.jaerosci.2015.12.006).Greiffo, F.R. ; Eickelberg, O. ; Fernandez, I.E.
Systems medicine advances in interstitial lung disease.Johnston, B.D. ; Kreyling, W.G. ; Pfeiffer, C. ; Schäffler, M. ; Sarioglu, H. ; Ristig, S. ; Hirn, S. ; Haberl, N. ; Thalhammer, S. ; Hauck, S.M. ; Semmler-Behnke, M. ; Epple, M. ; Hühn, J. ; del Pino, P. ; Parak, W.J.
Colloidal stability and surface chemistry are key factors for the composition of the protein corona of inorganic gold nanoparticles.Bartel, S. ; Jatzlauk, G. ; Kepert, I. ; Fonseca, J. ; Müller, C. ; Milger, K. ; Hochwind, K. ; Kostric, M. ; Eickelberg, O. ; Schloter, M. ; Hartmann, A. ; Schmitt-Kopplin, P. ; Krauss-Etschmann, S.
The metabolite D-tryptophan from probiotic bacteria ameliorates allergic airway disease and influences the gut microbiome.Röhm, M. ; Carle, S. ; Maigler, F. ; Flamm, J. ; Kramer, V. ; Mavoungou, C. ; Schmid, O. ; Schindowski, K.
A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery.Xu, Q. ; Liu, X. ; Wang, X. ; Hua, Y. ; Chen, J. ; Li, J. ; Wang, Y. ; Stöger, T. ; Chen, S. ; Huang, N.
Growth arrest-specific protein 7 regulates the murine M1 alveolar macrophage polarization.Oak, P. ; Pritzke, T. ; Thiel, I. ; Koschlig, M. ; Mous, D.S. ; Windhorst, A. ; Jain, N. ; Eickelberg, O. ; Foerster, K. ; Schulze, A. ; Goepel, W. ; Reicherzer, T. ; Ehrhardt, H. ; Rottier, R.J. ; Ahnert, P. ; Gortner, L. ; Desai, T.J. ; Hilgendorff, A.
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.Segura, M.T. ; Demmelmair, H. ; Krauss-Etschmann, S. ; Nathan, P. ; Dehmel, S. ; Padilla, M.C. ; Rueda, R. ; Koletzko, B. ; Campoy, C.
Maternal BMI and gestational diabetes alter placental lipid transporters and fatty acid composition.Milger, K. ; Yu, Y. ; Brudy, E. ; Irmler, M. ; Skapenko, A. ; Mayinger, M. ; Lehmann, M. ; Beckers, J. ; Reichenberger, F. ; Behr, J. ; Eickelberg, O. ; Königshoff, M. ; Krauss-Etschmann, S.
Pulmonary CCR2+CD4+ T cells are immune regulatory and attenuate lung fibrosis development.Spella, M. ; Marazioti, A. ; Arendt, K.A.M. ; Stathopoulos, G.T.
RAS oncogenes direct metastasis.Lehmann, M. ; Korfei, M. ; Mutze, K. ; Klee, S. ; Skronska-Wasek, W. ; Alsafadi, H.N. ; Ota, C. ; Costa, R. ; Schiller, H. B. ; Lindner, M. ; Wagner, A. ; Günther, A.L. ; Königshoff, M.
Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.Spella, M. ; Lilis, I. ; Stathopoulos, G.T.
Shared epithelial pathways to lung repair and disease.Engel, M. ; Endesfelder, D. ; Schloter-Hai, B. ; Kublik, S. ; Granitsiotis, M.S. ; Boschetto, P. ; Stendardo, M. ; Barta, I. ; Döme, B. ; Deleuze, J.F. ; Boland, A. ; Müller-Quernheim, J. ; Prasse, A. ; Welte, T. ; Hohlfeld, J. ; Subramanian, D. ; Parr, D. ; Gut, I.G. ; Greulich, T. ; Koczulla, A.R. ; Nowinski, A. ; Gorecka, D. ; Singh, D. ; Gupta, S. ; Brightling, C.E. ; Hoffmann, H. ; Frankenberger, M. ; Hofer, T.P. ; Burggraf, D. ; Heiss-Neumann, M.S. ; Ziegler-Heitbrock, L. ; Schloter, M. ; zu Castell, W.
Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome.Gradl, R. ; Dierolf, M. ; Hehn, L. ; Günther, B. ; Yildirim, A.Ö. ; Gleich, B. ; Achterhold, K. ; Pfeiffer, F. ; Morgan, K.S.
Propagation-based phase-contrast x-ray imaging at a compact light source.Burgstaller, G. ; Oehrle, B. ; Gerckens, M. ; White, E.S. ; Schiller, H. B. ; Eickelberg, O.
The instructive extracellular matrix of the lung: Basic composition and alterations in chronic lung disease.Schiller, H. B. ; Mayr, C.H. ; Leuschner, G. ; Strunz, M. ; Staab-Weijnitz, C.A. ; Preisendörfer, S. ; Eckes, B. ; Moinzadeh, P. ; Krieg, T. ; Schwartz, D.A. ; Hatz, R.A. ; Behr, J. ; Mann, M. ; Eickelberg, O.
Deep proteome profiling reveals common prevalence of MZB1-positive plasma B cells in human lung and skin fibrosis.Manfrini, N. ; Ricciardi, S. ; Miluzio, A. ; Fedeli, M. ; Scagliola, A. ; Gallo, S. ; Brina, D. ; Adler, T. ; Busch, D.H. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Biffo, S.
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.Koch, A.
Positive Wirkung inhalativer Kortikoide bei Asthma mit < 2 Symptomtagen.Karp, N.A. ; Mason, J. ; Beaudet, A.L. ; Benjamini, Y. ; Bower, L. ; Braun, R.E. ; Brown, S.D.M. ; Chesler, E.J. ; Dickinson, M.E. ; Flenniken, A.M. ; Fuchs, H. ; Hrabě de Angelis, M. ; Gao, X. ; Guo, S. ; Greenaway, S. ; Heller, R. ; Herault, Y. ; Justice, M.J. ; Kurbatova, N. ; Lelliott, C.J. ; Lloyd, K.C.K. ; Mallon, A.M. ; Mank, J.E. ; Masuya, H. ; McKerlie, C. ; Meehan, T.F. ; Mott, R.F. ; Murray, S.A. ; Parkinson, H. ; Ramirez-Solis, R. ; Santos, L. ; Seavitt, J.R. ; Smedley, D. ; Sorg, T. ; Speak, A.O. ; Steel, K.P. ; Svenson, K.L. ; Wakana, S. ; West, D. ; Wells, S. ; Westerberg, H. ; Yaacoby, S. ; White, J.K. ; International Mouse Phenotyping Consortium (Aguilar-Pimentel, J.A. ; Treise, I. ; Moreth, K. ; Stöger, T. ; Amarie, O.V. ; Neff, C. ; Wurst, W. ; Calzada-Wack, J. ; Marschall, S. ; Brommage, R. ; Steinkamp, R. ; Lengger, C. ; Östereicher, M.A. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Yildirim, A.Ö. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Seisenberger, C. ; Bürger, A. ; Graw, J. ; Eickelberg, O. ; Schmidt-Weber, C.B. ; Gailus-Durner, V. ; Beckers, J. ; Rathkolb, B. ; Rozman, J.) ; Becker, L.
Prevalence of sexual dimorphism in mammalian phenotypic traits.Kaestle, M. ; Bartel, S. ; Geillinger-Kästle, K. ; Irmler, M. ; Beckers, J. ; Ryffel, B. ; Eickelberg, O. ; Krauss-Etschmann, S.
microRNA cluster 106a~363 is involved in T-Helper 17 (Th17) cell differentiation.Ganguly, K. ; Ettehadieh, D. ; Upadhyay, S. ; Takenaka, S. ; Adler, T. ; Karg, E.W. ; Krombach, F. ; Kreyling, W.G. ; Schulz, H. ; Schmid, O. ; Stöger, T.
Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: Comparison of inhalation versus intra-arterial infusion exposures in mice.Tufman, A. ; Kahnert, K. ; Kauffmann-Guerrero, D. ; Manapov, F. ; Milger, K. ; Müller-Lisse, U. ; Winter, H. ; Huber, R.M. ; Schneider, C.
Clinical relevance of the M1b and M1c descriptors from the proposed TNM 8 classification of lung cancer.Hose, A.J. ; Depner, M. ; Illi, S. ; Lau, S. ; Keil, T. ; Wahn, U. ; Fuchs, O. ; Pfefferle, P.I. ; Schmaußer-Hechfellner, E. ; Genuneit, J. ; Lauener, R. ; Karvonen, A.M. ; Roduit, C. ; Dalphin, J.-C. ; Riedler, J. ; Pekkanen, J. ; von Mutius, E. ; Ege, M.J. ; Bauer, C.P. ; Forster, J. ; Zepp, F. ; Wahn, V. ; Schuster, A. ; Bergmann, R.L. ; Bergmann, K.E. ; Reich, A. ; Grabenhenrich, L. ; Schaub, B. ; Loss, G.J. ; Renz, H. ; Kabesch, M. ; Roponen, M. ; Hyvärinen, A. ; Tiittanen, P. ; Remes, S. ; Braun-Fahrländer, C. ; Frei, R. ; Kaulek, V. ; Dalphin, M. ; Doekes, G. ; Blümer, N. ; Frey, U.H.
Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts.Garrett, L. ; Becker, L. ; Rozman, J. ; Puk, O. ; Stöger, T. ; Yildirim, A.Ö. ; Bohla, A. ; Eickelberg, O. ; Hans, W. ; Prehn, C. ; Adamski, J. ; Klopstock, T. ; Rácz, I. ; Zimmer, A. ; Klingenspor, M. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Hrabě de Angelis, M. ; Graw, J. ; Hölter, S.M.
Fgf9Y162C mutation alters information processing and social memory in mice.Αgalioti, T. ; Giannou, A.D. ; Krontira, A.C. ; Kanellakis, N.I. ; Kati, D. ; Vreka, M. ; Pepe, M. ; Spella, M. ; Lilis, I. ; Zazara, D.E. ; Nikolouli, E. ; Spiropoulou, N. ; Papadakis, A. ; Papadia, K. ; Voulgaridis, A. ; Harokopos, V. ; Stamou, P. ; Meiners, S. ; Eickelberg, O. ; Snyder, L.A. ; Antimisiaris, S.G. ; Kardamakis, D. ; Psallidas, I. ; Μarazioti, A. ; Stathopoulos, G.T.
Mutant KRAS promotes malignant pleural effusion formation.Zawada, A.M. ; Zhang, L. ; Emrich, I.E. ; Rogacev, K.S. ; Krezdorn, N. ; Rotter, B. ; Fliser, D. ; Devaux, Y. ; Ziegler-Heitbrock, L. ; Heine, G.H.
Reprint of: MicroRNA profiling of human intermediate monocytes.Milger, K. ; Götschke, J. ; Krause, L. ; Nathan, P. ; Alessandrini, F. ; Tufman, A. ; Fischer, R. ; Bartel, S. ; Theis, F.J. ; Behr, J. ; Dehmel, S. ; Müller, N.S. ; Kneidinger, N. ; Krauss-Etschmann, S.
Identification of a plasma miRNA biomarker-signature for allergic asthma: A translational approach.Greiffo, F.R. ; Fernandez, I.E. ; Frankenberger, M. ; Ortega-Gomez, A. ; Behr, J. ; Soehnlein, O. ; Eickelberg, O.
Monocyte immunophenotyping reflects aberrant activation patterns in interstitial lung disease patients.Heinzelmann, K. ; Noskovicova, N. ; Lehmann, M. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Königshoff, M. ; Eickelberg, O.
Cd82 is a novel mediator of fibroblast proliferation.Fernandez, I.E. ; Roy, R. ; Greiffo, F.R. ; Frankenberger, M. ; Behr, J. ; Forrest, A.R. ; Eickelberg, O.
Quantitative proteomics reveals novel fibrotic networks of myeloid-derived suppressor cell and monocytes in ipf.John-Schuster, G. ; Conlon, T.M. ; Günter, S. ; Eickelberg, O. ; Heikenwalder, M. ; Yildirim, A.Ö.
Lymphotoxin-beta-receptor blockade prevents cigarette smoke-induced COPD.Conlon, T.M. ; Hackl, M. ; Bartel, J. ; Krumsiek, J. ; Irmler, M. ; Beckers, J. ; Theis, F.J. ; Eickelberg, O. ; Yildirim, A.Ö.
2d cross-omics integrated enrichment analysis of human and mice COPD lungs reveal novel pathological mechanisms of disease progression.Conlon, T.M. ; Jia, J. ; Gao, J. ; Heinzelmann, K. ; Tasdemir, D. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Loss of the cholesterol metabolizing enzyme Ch25h protects against cigarette smoke-induced COPD.Jarosch, I. ; Schneeberger, T. ; Gloeckl, R. ; Kreuter, M. ; Benstz, J. ; Frankenberger, M. ; Neurohr, C. ; Prasse, A. ; Behr, J. ; Kenn, K.
Different effects of pulmonary rehabilitation in Anxious Vs. Non-Anxious patients with idiopathic pulmonary fibrosis - a pilot study.Maldonado, M. ; Ortiz-Quintero, B. ; Herrera, I. ; Ramirez, R. ; Staab-Weijnitz, C.A. ; Eickelberg, O. ; Salgado-Aguayo, A. ; Selman, M. ; Pardo, A.
Matrix metalloproteinase (mmp)-28 is expressed in alveolar epithelial cells in idiopathic pulmonary fibrosis and increases their proliferation and migration.Ciolek, F. ; Heinzelmann, K. ; Eickelberg, O. ; Königshoff, M. ; Baarsma, H.
Regulation and function of non-canonical Wnt-5a in human lung fibroblasts.Welk, V. ; Meul, T. ; Merl-Pham, J. ; Korfei, M. ; Koch, I. ; Semren, N. ; Guenther, A. ; Lindner, M. ; Hauck, S.M. ; Eickelberg, O. ; Meiners, S.
Proteasomal activator 200 (pa200) regulates cellular proliferation: A putative role for Ipf and lung cancer pathogenesis.Ota, C. ; Ng-Blichfeldt, J. ; Mutze, K. ; Baarsma, H. ; Skronska-Wasek, W. ; Königshoff, M.
Hopx-Wnt crosstalk regulates alveolar homeostasis.Bartel, S. ; Schulz, N. ; Alessandrini, F. ; Schamberger, A.C. ; Pagel, P. ; Theis, F.J. ; Milger, K. ; Nößner, E. ; Stick, S.M. ; Kicic, A. ; Eickelberg, O. ; Freishtat, R.J. ; Krauss-Etschmann, S.
Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.Gromann, L.B. ; Scherer, K. ; Yaroshenko, A. ; Bölükbas, D.A. ; Hellbach, K. ; Meinel, F.G. ; Braunagel, M. ; Eickelberg, O. ; Reiser, M.F. ; Pfeiffer, F. ; Meiners, S. ; Herzen, J.
First experiences with in-vivo x-ray dark-field imaging of lung cancer in mice.Kneidinger, N. ; Milger, K. ; Janitza, S. ; Ceelen, F. ; Leuschner, G. ; Dinkel, J. ; Königshoff, M. ; Weig, T. ; Schramm, R. ; Winter, H. ; Behr, J. ; Neurohr, C.
Lung volumes predict survival in patients with chronic lung allograft dysfunction.Giopanou, I. ; Arendt, K.A.M. ; Stathopoulos, G.T.
Lung carcinogenesis and fibrosis taken together: Just coincidence?Lehmann, M. ; Buhl, L. ; Klee, S. ; Wagner, D.E. ; Behr, J. ; Lindner, M. ; Königshoff, M.
Effects of nintedanib and pirfenidone on alveolar epithelial cells in 2d and 3d lung cultures.Hilgendorff, A. ; Pritzke, T. ; Markmann, M. ; Oak, P. ; Koschlig, M. ; Hossain, H. ; Desai, T.
Time dependant effects of mechanical ventilation and hyperoxia on central signalling pathways in the developing lung identified by comprehensive transcriptome analysis.Yin, R. ; Zhang, P. ; Liu, X. ; Chen, Y. ; Tao, Z. ; Ai, L. ; Li, J. ; Yang, Y. ; Li, M. ; Xue, C. ; Qian, J. ; Wang, X. ; Chen, J. ; Li, Y. ; Xiong, Y. ; Zhang, J. ; Stöger, T. ; Bi, Y. ; Ding, Z.
Dispersal and transmission of avian paramyxovirus serotype 4 among wild birds and domestic poultry.Ganguly, K. ; George, L. ; Thimraj, T.A. ; Upadhyay, S. ; Schulz, H. ; Stöger, T.
Skewed alveolar macrophage polarization signature in mice with impaired pulmonary function following carbon nanoparticle exposure.Alsafadi, H.N. ; Lehmann, M. ; Lindner, M. ; Peschel, B. ; Königshoff, M. ; Wagner, D.E.
An ex vivo human model of idiopathic pulmonary fibrosis using precision cut lung slices.Noskovicova, N. ; Heinzelmann, K. ; Burgstaller, G. ; Eickelberg, O.
Cub domain containing protein 1/transforming growth factor-beta 1 cross-talk regulates (myo)fibroblast differentiation.Ng-Blichfeldt, J. ; Ota, C. ; Stolk, J. ; Hiemstra, P. ; Gosens, R. ; Königshoff, M.
Wnt activity marks lung progenitors capable of forming spheres in vitro.Sarker, R.S. ; Conlon, T.M. ; Dorer, J. ; Burgstaller, G. ; Merthan, L. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Bustin, M. ; Furusawa, T. ; Eickelberg, O. ; Yildirim, A.Ö.
Epigenetic histone-1 modulator Hmgn5 regulates cellular apoptosis In COPD pathogenesis.Houssaini, A. ; Breau, M. ; Kebe, K. ; Abid, S. ; Marcos, E. ; Lipskaia, L. ; Rideau, D. ; Parpaleix, A. ; Huang, J. ; Amsellem, V. ; Maitre, B. ; Bizard, E. ; Vienney, N. ; Luka, C. ; Validyre, P. ; Boczkowski, J. ; Derumeaux, G. ; Bernard, D. ; Meiners, S. ; Adnot, S.
Activation of the Mtor pathway drives lung cell senescence and emphysema in chronic obstructive pulmonary disease (COPD).Smirnova, N.F. ; Conlon, T.M. ; Yildirim, A.Ö. ; Eickelberg, O.
Orthotopic lung transplantation in a single- mismatch-based mouse model shows signs of chronic lung allograft dysfunction (clad) associated to inducible bronchus-associated lymphoid tissue (ibalt) formation.Hilgendorff, A. ; Foerster, K. ; Sass, S. ; Stoecklein, S. ; Dietrich, O. ; Pomschar, A. ; Schulze, A. ; Huebener, C. ; Theis, F.J. ; Erhardt, H. ; Flemmer, A.W. ; Ertl-Wagner, B.
Discrimination of pulmonary changes in neonatal chronic lung disease by a new Mri score.Oak, P. ; Pritzke, T. ; Koschlig, M. ; Windhorst, A. ; Jain, N. ; Reicherzer, T. ; Ehrhardt, H. ; Frankenberger, M. ; Schwarz, M.A. ; Hilgendorff, A.
Monocyte-centred inflammatory response driving pulmonary injury in neonatal chronic lung disease.Oak, P. ; Kamgari, N. ; Pritzke, T. ; John-Schuster, G. ; Jia, J. ; Yildirim, A.Ö. ; Hilgendorff, A.
Enhanced vulnerability of the developing lungs by moderate prenatal cigarette smoke upon postnatal injury.Kammerl, I.E. ; Chen, S. ; Vergara, E.E. ; Irmler, M. ; Beckers, J. ; Muchamuel, T. ; Kirk, C. ; Florea, B.I. ; Overkleeft, H.S. ; Eickelberg, O. ; Meiners, S. ; Stöger, T.
Deficiency of immunoproteasome subunits increases alternative polarization of alveolar macrophages.Baarsma, H.A. ; Skronska-Wasek, W. ; Mutze, K. ; Ciolek, F. ; Wagner, D.E. ; John-Schuster, G. ; Heinzelmann, K. ; Guenther, A. ; Bracke, K.R. ; Dagouassat, M. ; Boczkowski, J. ; Brusselle, G.G. ; Smits, R. ; Eickelberg, O. ; Yildirim, A.Ö. ; Königshoff, M.
Non-canonical Wnt-5a signaling impairs endogenous lung repair in COPD.Lopez, C.B. ; Conlon, T.M. ; Ertuez, Z. ; Eickelberg, O. ; Yildirim, A.Ö.
Inflammatory response of lung recruited macrophages is partly regulated by non-canonical notch pathway in chronic obstructive pulmonary diseases (COPD).Schrom, E. ; Huber, M. ; Aneja, M.K. ; Dohmen, C. ; Emrich, D. ; Geiger, J. ; Hasenpusch, G. ; Herrmann-Janson, A. ; Kretzschmann, V. ; Mykhailyk, O. ; Pasewald, T. ; Oak, P. ; Hilgendorff, A. ; Wohlleber, D. ; Hoymann, H. ; Schaudien, D. ; Plank, C. ; Rudolph, C. ; Kubisch-Dohmen, R.
Translation of angiotensin-converting enzyme 2 upon liver- and lung-targeted delivery of optimized chemically modified mRNA.Guarino, C. ; Hamon, Y. ; Croix, C. ; Lamort, A.-S. ; Dallet-Choisy, S. ; Marchand-Adam, S. ; Lesner, A. ; Baranek, T. ; Viaud-Massuard, M.C. ; Lauritzen, C. ; Pedersen, J.H. ; Heuze-Vourc'h, N. ; Si-Tahar, M. ; Firatli, E. ; Jenne, D. ; Gauthier, F. ; Horwitz, M.S. ; Borregaard, N. ; Korkmaz, B.
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.Scherer, K. ; Yaroshenko, A. ; Bölükbas, D.A. ; Gromann, L.B. ; Hellbach, K. ; Meinel, F.G. ; Braunagel, M. ; Berg, J.V. ; Eickelberg, O. ; Reiser, M.F. ; Pfeiffer, F. ; Meiners, S. ; Herzen, J.
X-ray dark-field radiography - in-vivo diagnosis of lung cancer in mice.Giannou, A.D. ; Marazioti, A. ; Kanellakis, N.I. ; Giopanou, I. ; Lilis, I. ; Zazara, D.E. ; Ntaliarda, G. ; Kati, D. ; Armenis, V. ; Giotopoulou, G.A. ; Krontira, A.C. ; Lianou, M. ; Agalioti, T. ; Vreka, M. ; Papageorgopoulou, M. ; Fouzas, S. ; Kardamakis, D. ; Psallidas, I. ; Spella, M. ; Stathopoulos, G.T.
NRAS destines tumor cells to the lungs.Oommen, E. ; Hummel, A.M. ; Allmannsberger, L. ; Cuthbertson, D. ; Carette, S. ; Pagnoux, C. ; Hoffman, G.S. ; Jenne, D. ; Khalidi, N.A. ; Koening, C. ; Langford, C. ; McAlear, C. ; Moreland, L. ; Seo, P. ; Sreih, A. ; Ytterberg, S. ; Merkel, P. ; Specks, U. ; Monach, P.
IgA antibodies to myeloperoxidase in patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss).Gall, H. ; Felix, J.F. ; Schneck, F.K. ; Milger, K. ; Sommer, N. ; Voswinckel, R. ; Franco, O.H. ; Hofman, A. ; Schermuly, R.T. ; Weissmann, N. ; Grimminger, F. ; Seeger, W. ; Ghofrani, H.A.
The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups.Kreyling, W.G. ; Holzwarth, U. ; Haberl, N. ; Kozempel, J. ; Wenk, A. ; Hirn, S. ; Schleh, C. ; Schäffler, M. ; Lipka, J. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics of titanium dioxide nanoparticles after intratracheal instillation in rats (Part 3).Kreyling, W.G. ; Holzwarth, U. ; Schleh, C. ; Kozempel, J. ; Wenk, A. ; Haberl, N. ; Hirn, S. ; Schäffler, M. ; Lipka, J. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics of titanium dioxide nanoparticles after oral application in rats (Part 2).Kreyling, W.G. ; Holzwarth, U. ; Haberl, N. ; Kozempel, J. ; Hirn, S. ; Wenk, A. ; Schleh, C. ; Schäffler, M. ; Lipka, J. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics of titanium dioxide nanoparticles after intravenous injection in rats (Part 1).Klar, K. ; Perchermeier, S. ; Bhattacharjee, S. ; Harb, H. ; Adler, T. ; Istvanffy, R. ; Loffredo-Verde, E. ; Oostendorp, R. ; Renz, H. ; Prazeres da Costa, C.U.
Chronic schistosomiasis during pregnancy epigenetically reprograms T cell differentiation in offspring of infected mothers.Tsai, J.M. ; Koh, P.W. ; Stefanska, A. ; Xing, L. ; Walmsley, G.G. ; Poux, N. ; Weissman, I.L. ; Rinkevich, Y.
Localized hepatic lobular regeneration by central-vein-associated lineage-restricted progenitors.Costa, R. ; Königshoff, M.
Linking wnt signaling to mucosal inflammation.Taggart, C. ; Mall, M.A. ; Lalmanach, G. ; Cataldo, D. ; Ludwig, A. ; Janciauskiene, S. ; Heath, N. ; Meiners, S. ; Overall, C.M. ; Schultz, C. ; Turk, B. ; Borensztajn, K.S.
Protean proteases: At the cutting edge of lung diseases.Giopanou, I. ; Lilis, I. ; Papaleonidopoulos, V. ; Agalioti, T. ; Kanellakis, N.I. ; Spiropoulou, N. ; Spella, M. ; Stathopoulos, G.T.
Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis.Papadia, K. ; Markoutsa, E. ; Mourtas, S. ; Giannou, A.D. ; La Ferla, B. ; Nicotra, F. ; Salmona, M. ; Klepetsanis, P. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Multifunctional LUV liposomes decorated for BBB and amyloid targeting. A. In vitro proof-of-concept.Fuchs, O. ; Bahmer, T. ; Rabe, K.F. ; von Mutius, E.
Asthma transition from childhood into adulthood.Geiger, S. ; Hereth, M. ; Forster, D. ; Hollauer, C. ; Ballester, C.F. ; Hermann, E. ; Yildirim, A.Ö. ; Guenther, C.
Amelioration of lung function and pulmonary tissue regeneration after treatment with AAT-expressing human MSCS in a murine model of elastase-induced emphysema.Loerz, C. ; Staab-Weijnitz, C.A. ; Huebbe, P. ; Giller, K. ; Metges, C. ; Rimbach, G. ; Maser, E.
Regulation of 11β-hydroxysteroid dehydrogenase type 1 following caloric restriction and re-feeding is species dependent.Zensen, C. ; Fernandez, I.E. ; Eickelberg, O. ; Feldmann, J. ; Lohmüller, T.
Detecting swelling states of red blood cells by "Cell-fluid coupling spectroscopy".Poobalasingam, T. ; Yates, L.L. ; Walker, S.A. ; Pereira, M. ; Gross, N.Y. ; Ali, A. ; Kolatsi-Joannou, M. ; Jarvelin, M.R. ; Pekkanen, J. ; Papakrivopoulou, E. ; Long, D.A. ; Griffiths, M. ; Wagner, D.E. ; Königshoff, M. ; Hind, M. ; Minelli, C. ; Lloyd, C.M. ; Dean, C.H.
Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.Malik, R. ; Dau, T. ; Gonik, M. ; Sivakumar, A. ; Deredge, D.J. ; Edeleva, E.V. ; Götzfried, J. ; van der Laan, S.W. ; Pasterkamp, G. ; Beaufort, N. ; Seixas, S. ; Bevan, S. ; Lincz, L.F. ; Holliday, E.G. ; Burgess, A.I. ; Rannikmäe, K. ; Minnerup, J. ; Kriebel, J. ; Waldenberger, M. ; Müller-Nurasyid, M. ; Lichtner, P. ; Saleheen, D. ; Rothwell, P.M. ; Levi, C. ; Attia, J. ; Sudlow, C.L. ; Braun, D. ; Markus, H.S. ; Wintrode, P.L. ; Berger, K. ; Jenne, D. ; Dichgans, M.
Common coding variant in SERPINA1 increases the risk for large artery stroke.Vonk, J.M. ; Scholtens, S. ; Postma, D.S. ; Moffatt, M.F. ; Jarvis, D. ; Ramasamy, A. ; Wjst, M. ; Omenaas, E.R. ; Bouzigon, E. ; Demenais, F. ; Nadif, R. ; Siroux, V. ; Polonikov, A.V. ; Solodilova, M. ; Ivanov, V.P. ; Curjuric, I. ; Imboden, M. ; Kumar, A. ; Probst-Hensch, N. ; Ogorodova, L.M. ; Puzyrev, V.P. ; Bragina, E.Y. ; Freidin, M.B. ; Nolte, I.M. ; Farrall, A.M. ; Cookson, W.O.C.M. ; Strachan, D.P. ; Koppelman, G.H. ; Boezen, H.M.
Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.Alsafadi, H.N. ; Staab-Weijnitz, C.A. ; Lehmann, M. ; Lindner, M. ; Peschel, B. ; Königshoff, M. ; Wagner, D.E.
An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.Knüppel, L. ; Ishikawa, Y. ; Aichler, M. ; Heinzelmann, K. ; Hatz, R. ; Behr, J. ; Walch, A.K. ; Bächinger, H.P. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
A novel antifibrotic mechanism of nintedanib and pirfenidone: Inhibition of collagen fibril assembly.Papadia, K. ; Giannou, A.D. ; Markoutsa, E. ; Bigot, C. ; Vanhoute, G. ; Mourtas, S. ; der Linden, A.V. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Multifunctional LUV liposomes decorated for BBB and amyloid targeting - B. In vivo brain targeting potential in wild-type and APP/PS1 mice.Skronska-Wasek, W. ; Mutze, K. ; Baarsma, H.A. ; Alsafadi, H.N. ; Lehmann, M. ; Costa, R. ; Wagner, D.E. ; Yildirim, A.Ö. ; Königshoff, M.
Reduced frizzled receptor 4 expression prevents WNT/β-catenin-driven alveolar lung repair in COPD.Sattler, C. ; Moritz, F. ; Chen, S. ; Steer, B. ; Kutschke, D. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schmitt-Kopplin, P. ; Adler, H. ; Stöger, T.
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.Altmäe, S. ; Segura, M.T. ; Esteban, F.J. ; Bartel, S. ; Brandi, P. ; Irmler, M. ; Beckers, J. ; Demmelmair, H. ; López-Sabater, C. ; Koletzko, B. ; Krauss-Etschmann, S. ; Campoy, C.
Maternal pre-pregnancy obesity is associated with altered placental transcriptome.Baarsma, H.A. ; Skronska-Wasek, W. ; Mutze, K. ; Ciolek, F. ; Wagner, D.E. ; John-Schuster, G. ; Heinzelmann, K. ; Günther, A. ; Bracke, K.R. ; Dagouassat, M. ; Boczkowski, J. ; Brusselle, G.G. ; Smits, R. ; Eickelberg, O. ; Yildirim, A.Ö. ; Königshoff, M.
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.Zawada, A.M. ; Zhang, L. ; Emrich, I.E. ; Rogacev, K.S. ; Krezdorn, N. ; Rotter, B. ; Fliser, D. ; Devaux, Y. ; Ziegler-Heitbrock, L. ; Heine, G.H.
MicroRNA profiling of human intermediate monocytes.Möller, W. ; Sheng Feng, M.S. ; Domanski, U. ; Franke, K.-J. ; Celik, G. ; Bartenstein, P. ; Becker, S. ; Meyer, G. ; Schmid, O. ; Eickelberg, O. ; Tatkov, S. ; Nilius, G.
Nasal high flow reduces dead space.Storch, U. ; Forst, A. ; Pardatscher, F. ; Erdogmus, S. ; Philipp, M. ; Gregoritza, M. ; Mederos y Schnitzlera, M. ; Gudermann, T.
Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.Hofmann, K. ; Fiedler, S. ; Vierkotten, S. ; Weber, J. ; Klee, S. ; Jia, J. ; Zwickenpflug, W. ; Flockerzi, V. ; Storch, U. ; Yildirim, A.Ö. ; Gudermann, T. ; Königshoff, M. ; Dietrich, A.
Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.Mossina, A. ; Lukas, C. ; Merl-Pham, J. ; Uhl, F.E. ; Mutze, K. ; Schamberger, A.C. ; Staab-Weijnitz, C.A. ; Jia, J. ; Yildirim, A.Ö. ; Königshoff, M. ; Hauck, S.M. ; Eickelberg, O. ; Meiners, S.
Cigarette smoke alters the secretome of lung epithelial cells.Campbell, B. ; Raherison, C. ; Lodge, C.J. ; Lowe, A.J. ; Gislason, T. ; Heinrich, J. ; Sunyer, J. ; Gómez Real, F. ; Norbäck, D. ; Matheson, M.C. ; Wjst, M. ; Dratva, J. ; de Marco, R. ; Jarvis, D. ; Schlünssen, V. ; Janson, C. ; Leynaert, B. ; Svanes, C. ; Dharmage, S.C.
The effects of growing up on a farm on adult lung function and allergic phenotypes: An international population-based study.Kepert, I. ; Fonseca, J. ; Müller, C. ; Milger, K. ; Hochwind, K. ; Kostric, M. ; Fedoseeva, M. ; Ohnmacht, C. ; Dehmel, S. ; Nathan, P. ; Bartel, S. ; Eickelberg, O. ; Schloter, M. ; Hartmann, A. ; Schmitt-Kopplin, P. ; Krauss-Etschmann, S.
D-Tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease.Hilgendorff, A. ; Windhorst, A. ; Klein, M. ; Tchatalbachev, S. ; Windemuth-Kieselbach, C. ; Kreuder, J. ; Heckmann, M. ; Gkatzoflia, A. ; Ehrhardt, H. ; Mysliwietz, J. ; Maier, M. ; Izar, B. ; Billion, A. ; Gortner, L. ; Chakraborty, T. ; Hossain, H.
Gene expression profiling at birth characterizing the preterm infant with early onset infection.