Publications
Welk, V.
Dissecting the role of proteasome activators in lung biology and disease.Pepe, M. ; Pelizza, F. ; Lamort, A. ; Kanellakis, N.I. ; Stathopoulos, G.T.
Alteration patterns of tobacco carcinogens in lung adenocarcinoma reveal novel KRAS-addicted candidate oncogenes.Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Eickelberg, O.
Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging.De Santis, M. ; Ota, C. ; Costa, R. ; Doryab, A. ; Alsafadi, H.N. ; Bolukbas, D. ; Königshoff, M. ; Wagner, D.
Development of a hybrid alginate-ECM hydrogel as a potential bioink for 3D bioprinting.Welk, V. ; Meul, T. ; Lukas, C. ; Bolukbas, D. ; Koch, I. ; Lindner, M. ; Meiners, S.
Analyzing the role of proteasome activator 200 (PA200) in lung cancer.Knüppel, L. ; Heinzelmann, K. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FKBP10 regulates fibroblast migration via synthesis of collagen VI.Lamort, A. ; Weiss, S. ; Lillis, I. ; Armenis, V. ; Arendt, K.A.M. ; Pepe, M. ; Klotz, L.V. ; Marazioti, A. ; Spella, M. ; Giopanou, I. ; Ntaliarda, G. ; Giotopoulou, G.A. ; Lianou, M. ; Oplopoiou, M. ; Kauka, K. ; Jenne, D. ; Stathopoulos, G.T.
Tumor-derived granulocyte chemotactic protein 2 cooperates with neutrophil proteinase 3 to drive lung adenocarcinoma.Fernandez, I.E. ; Greiffo, F.R. ; Roi, R. ; Behr, J. ; Forrest, A.R. ; Eickelberg, O.
Circulating MDSC modulate IPF progression by orchestrating immunosuppressive and pro-fibrotic networks.Lambert, K.A. ; Lodge, C. ; Prendergast, L.A. ; Bowatte, G. ; Lowe, A. ; Wjst, M. ; Abramson, M.J. ; Dharmage, S.C. ; Erbas, B.
Associations between early life exposure to pollen and adolescent lung function are modified by residential greenness.Costa, R. ; Wagner, D.E. ; De Santis, M. ; Bailey, K.E. ; Doryab, A. ; Schorpp, K.K. ; Rothenaigner, I. ; Ota, C. ; Baarsma, H.A. ; Campillos, M.J. ; Hadian, K. ; Königshoff, M.
Novel compounds for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease.Wartenberg, M. ; Andrault, P. ; Schamberger, A.C. ; Chazeirat, T. ; Sizaret, D. ; Renault, J. ; Petit, A. ; Saidi, A. ; Guyetant, S. ; Courty, Y. ; Eickelberg, O. ; Lalmanach, G. ; Lecaille, F.
Cigarette smoke induces overexpression of cathepsin S in active smokers with and without COPD.Kindt-Dunjko, A. ; Foerster, K. ; Flemmer, A. ; Oak, P. ; Pomschar, A. ; Ertl-Wagner, B. ; Krumsiek, J. ; Hilgendorff, A.
Late Breaking Abstract - Protein signature stratifies severity of chronic lung disease in preterms after birth.Lopez, C.B. ; Conlon, T.M. ; Ertuz, Z. ; Eickelberg, O. ; Yildirim, A.Ö.
The novel notch ligand DNER modulates IFN. Levels in recruited macrophages by enhancing non-canonical notch during COPD progression.Lehmann, M. ; Klee, S. ; Kaufmann, G. ; Koenigshoff, M.
Human anti-Wnt1-inducible signaling protein (WISP) 1 antibodies attenuate experimental lung fibrosis ex vivo.Schmid, O. ; Möller, W. ; Stelzl, A. ; Lund, J. ; Yildirim, A.Ö. ; Krauss-Etschmann, S. ; Robichaud, A.
Preclinical experiments support recent clinical switch to delivered dose during methacholine bronchoprovocation testing.Smirnova, N.F. ; Morrone, C. ; Conlon, T.M. ; von Toerne, C. ; Hauck, S.M. ; Eickelberg, O. ; Yildirim, A.Ö.
A quantitative proteomics profiling of murine lung grafts indicates novel pathways associated with chronic lung allograft dysfunction.Knüppel, L. ; Merl-Pham, J. ; Hennen, E. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Hauck, S.M. ; Staab-Weijnitz, C.A.
A proteomic analysis of extracellular matrix from idiopathic pulmonary fibrosis patient-derived fibroblasts in response to transforming growth factor beta 1.Tsai, J.M. ; Sinha, R. ; Seita, J. ; Fernhoff, N. ; Christ, S. ; Koopmans, T. ; Krampitz, G.W. ; McKenna, K.M. ; Xing, L. ; Sandholzer, M. ; Sales, J.H. ; Shoham, M. ; McCracken, M. ; Joubert, L.M. ; Gordon, S.R. ; Poux, N. ; Wernig, G. ; Norton, J.A. ; Weissman, I.L. ; Rinkevich, Y.
Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers.Morrone, C. ; Smirnova, N.F. ; Kneidinger, N. ; Mann, M. ; Schiller, H.B. ; Eickelberg, O. ; Yildirim, A.Ö.
Increased peribronchiolar and perivascular cysteine protease activity is associated with bronchiolitis obliterans syndrome.Schittny, J.C. ; Möller, W. ; Holzwarth, U. ; Hirn, S. ; Wenk, A. ; Schleh, C. ; Schäffler, M. ; Haberl, N. ; Gibson, N. ; Kreyling, W.G.
Age-dependent deposition patterns and quantitative biokinetics of inhaled 20nm gold nanoparticles in rat lungs.Conlon, T.M. ; Sarker, R.S. ; Jia, J. ; Heinzelmann, K. ; Tasdemir, D. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Immuno-metabolomic regulation of B cell guided iBALT positioning drives cigarette smoke-induced COPD.Foerster, K. ; Ertl-Wagner, B. ; Sass, S. ; Stoecklein, S. ; Schoeppe, F. ; Dietrich, O. ; Pomschar, A. ; Schulze, A. ; Huebener, C. ; Theis, F.J. ; Ehrhardt, H. ; Flemmer, A. ; Hilgendorff, A.
Quantitative MRI measurements to detect pulmonary hypertension in bronchopulomnary dysplasia.Hu, Y. ; Skronska-Wasek, W. ; Ota, C. ; Mutze, K. ; Baarsma, H.A. ; Wagner, D.E. ; Lehmann, M. ; Bracke, K.R. ; Brusselle, G.G. ; Yildirim, A.Ö. ; Koenigshoff, M.
The progenitor cell marker LGR5 is reduced in epithelial cells in emphysema.Foerster, K. ; Sass, S. ; Pomschar, A. ; Ehrhardt, H. ; Naehrlich, L. ; Schulze, A. ; Flemmer, A. ; Huebener, C. ; Eickelberg, O. ; Theis, F.J. ; Dietrich, O. ; Ertl-Wagner, B. ; Hilgendorff, A.
Diagnosis of bronchopulmonary dysplasia using magnetic resonance imaging analysis.Heinzelmann, K. ; Gerckens, M. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Hilgendorff, A.
DPPIV expression in human lung fibroblasts affects phenotypic changes in fibrosis.Oak, P. ; Koschlig, M. ; Pritzke, T. ; Foerster, K. ; Ahnert, P. ; Windhorst, A. ; Reicherzer, T. ; Ehrhardt, H. ; Hilgendorff, A.
Gender specific response of the neonatal lung to postnatal injury.Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone treatment in pulmonary fibrosis detected by high resolution MALDI FTICR-mass spectrometry imaging.Preisendörfer, S. ; Knüppel, L. ; Ishikawa, Y. ; Binzenhöfer, L. ; Fernandez, I.E. ; Juan-Guardela, B.M. ; Ruppert, C. ; Guenther, A. ; Hatz, R. ; Behr, J. ; Kaminski, N. ; Schepers, A. ; Bachinger, H. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FK506 binding protein 11, a plasma cell-specific antibody folding catalyst, is increased in pulmonary fibrosis.Costa, R. ; Wagner, D.E. ; De Santis, M. ; Bailey, K.E. ; Doryab, A. ; Schorpp, K.K. ; Rothenaigner, I. ; Ota, C. ; Baarsma, H.A. ; Campillos, M. ; Hadian, K. ; Koenigshoff, M.
Drug repurposing for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease.Mahmutovic, L. ; Akcesme, B. ; Durakovic, C. ; Akcesme, F.B. ; Maric, A. ; Adilovic, M. ; Hamad, N. ; Wjst, M. ; Feeney, O. ; Semiz, S.
Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine.Jiang, D. ; Rinkevich, Y.
Defining skin fibroblastic cell types beyond CD90.Matthes, S. ; Stadler, J. ; Barton, J. ; Leuschner, G. ; Munker, D. ; Arnold, P. ; Villena-Hermoza, H. ; Frankenberger, M. ; Probst, P. ; Koch, A. ; Kneidinger, N. ; Milger, K. ; Behr, J. ; Neurohr, C.
Asthma features in severe COPD: Identifying treatable traits.Thompson, G.A. ; Moura, M.C. ; Nelson, D. ; Hummel, A.M. ; Jenne, D. ; Fervenza, F. ; Hoffman, G.S. ; Kallenberg, C.G.M. ; Langford, C. ; McCune, J.W. ; Merkel, P.A. ; Monach, P.A. ; Seo, P. ; Spiera, R.F. ; St Clair, E.W. ; Ytterberg, S.R. ; Stone, J.H. ; Robinson, W.H. ; Pang, Y. ; Specks, U.
Characterization of preferential recognition of a chimeric recombinant proteinase 3 variant by anti-neutrophil cytoplasmic antibodies.Ghosh, S. ; Drexler, I. ; Bhatia, S. ; Adler, H. ; Gennery, A.R. ; Borkhardt, A.
Interleukin-2-inducible T-cell kinase deficiency-new patients, new insight?Koopmans, T. ; Rinkevich, Y.
Mesothelial to mesenchyme transition as a major developmental and pathological player in trunk organs and their cavities.Ghosh, S. ; Drexler, I. ; Bhatia, S. ; Adler, H. ; Gennery, A.R. ; Borkhardt, A.
Erratum: Corrigendum: Interleukin-2-inducible T-cell kinase deficiency-new patients, new insight? (Frontiers in immunology (2018) 9 (979)).Oplopoiou, M. ; Kati, D. ; Ntaliarda, G. ; Giopanou, I. ; Papaleonidopoulos, V. ; Lilis, I. ; Stathopoulos, G.T.
Trp53 signaling in chemically induced lung adenocarcinoma.Ng-Blichfeldt, J.P. ; Schrik, A. ; Kortekaas, R.K. ; Noordhoek, J.A. ; Heijink, I.H. ; Hiemstra, P.S. ; Stolk, J. ; Königshoff, M. ; Gosens, R.
Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.Magkouta, S. ; Kollintza, A. ; Moschos, C. ; Spella, M. ; Skianis, I. ; Pappas, A. ; Vazakidou, M.E. ; Stathopoulos, G.T. ; Kalomenidis, I.
Role of angiopoietins in mesothelioma progression.Kreyling, W.G. ; Möller, W. ; Holzwarth, U. ; Hirn, S. ; Wenk, A. ; Schleh, C. ; Schäffler, M. ; Haberl, N. ; Gibson, N. ; Schittny, J.C.
Age-dependent rat lung deposition patterns of inhaled 20 manometer gold nanoparticles and their quantitative biokinetics in adult rats.Chen, Y. ; Ding, Z. ; Liu, X. ; Chen, J. ; Li, J. ; Fei, Y. ; Liu, Z. ; Stöger, T. ; Bi, Y. ; Yin, R.
Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China.Prange, R. ; Thiedmann, M. ; Bhandari, A. ; Mishra, N. ; Sinha, A. ; Häsler, R. ; Rosenstiel, P. ; Uliczka, K. ; Wagner, C. ; Yildirim, A.Ö. ; Fink, C. ; Roeder, T.
A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention.Roth, C.J. ; Förster, K. ; Hilgendorff, A. ; Ertl-Wagner, B. ; Wall, W.A. ; Flemmer, A.W.
Gas exchange mechanisms in preterm infants on HFOV - a computational approach.Lehmann, M. ; Buhl, L. ; Alsafadi, H.N. ; Klee, S. ; Hermann, S. ; Mutze, K. ; Ota, C. ; Lindner, M. ; Behr, J. ; Hilgendorff, A. ; Wagner, D.E. ; Königshoff, M.
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.Ota, C. ; Ng-Blichfeldt, J.P. ; Korfei, M. ; Alsafadi, H.N. ; Lehmann, M. ; Skronska-Wasek, W. ; De Santis, M. ; Guenther, A. ; Wagner, D.E. ; Königshoff, M.
Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis.De Santis, M. ; Bolukbas, D.A. ; Lindstedt, S. ; Wagner, D.E.
How to build a lung: Latest advances and emerging themes in lung bioengineering.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Witting, M. ; Aichler, M. ; Feuchtinger, A. ; Burgstaller, G. ; Verleden, S.E. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.Martin-Medina, A. ; Lehmann, M. ; Burgy, O. ; Hermann, S. ; Baarsma, H.A. ; Wagner, D.E. ; De Santis, M. ; Ciolek, F. ; Hofer, T.P. ; Frankenberger, M. ; Aichler, M. ; Lindner, M. ; Gesierich, W. ; Guenther, A. ; Walch, A.K. ; Coughlan, C. ; Wolters, P. ; Lee, J.S. ; Behr, J. ; Königshoff, M.
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.Schmitzer, M. ; Winter, H. ; Kneidinger, N. ; Meimarakis, G. ; Dick, A. ; Schramm, R. ; Klotz, L.V. ; Preissler, G. ; Strobl, N. ; von Dossow, V. ; Schneider, C. ; Weig, T. ; Hatz, R. ; Kauke, T.
Persistence of de novo donor-specific HLA-antibodies after lung transplantation: A potential marker of decreased patient survival.Spadaro, M. ; Winklmeier, S. ; Beltrán, E. ; Macrini, C. ; Höftberger, R. ; Schuh, E. ; Thaler, F.S. ; Gerdes, L.A. ; Laurent, S.A. ; Gerhards, R. ; Brändle, S. ; Dornmair, K. ; Breithaupt, C. ; Krumbholz, M. ; Moser, M. ; Kirshnamoorthy, G. ; Kamp, F. ; Jenne, D. ; Hohlfeld, R. ; Kümpfel, T. ; Lassmann, H. ; Kawakami, N. ; Meinl, E.
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.Magkrioti, C. ; Oikonomou, N. ; Kaffe, E. ; Mouratis, M.A. ; Xylourgidis, N. ; Barbayianni, I. ; Megadoukas, P. ; Harokopos, V. ; Valavanis, C. ; Chun, J. ; Kosma, A. ; Stathopoulos, G.T. ; Bouros, E. ; Bouros, D. ; Syrigos, K. ; Aidinis, V.
The autotaxin - lysophosphatidic acid axis promotes lung carcinogenesis.Meiners, S. ; Lloyd, C. ; Chambers, R.C.
Cell–matrix interactions in lung disease and regeneration: ERS lung science conference 2018 report.Heinzelmann, K. ; Lehmann, M. ; Gerckens, M. ; Noskovicova, N. ; Frankenberger, M. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Hilgendorff, A. ; Königshoff, M. ; Eickelberg, O.
Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis.Psallidas, I. ; Kanellakis, N.I. ; Gerry, S. ; Thézénas, M.L. ; Charles, P.D. ; Samsonova, A. ; Schiller, H. B. ; Fischer, R. ; Asciak, R. ; Hallifax, R.J. ; Mercer, R. ; Dobson, M. ; Dong, T. ; Pavord, I.D. ; Collins, G.S. ; Kessler, B.M. ; Pass, H.I. ; Maskell, N. ; Stathopoulos, G.T. ; Rahman, N.M.
Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): A multicohort analysis.Tsai, J.M. ; Weissman, I.L. ; Rinkevich, Y.
Partial lobular hepatectomy: A surgical model for morphologic liver regeneration.Seren, S. ; Rashed Abouzaid, M. ; Eulenberg-Gustavus, C. ; Hirschfeld, J. ; Soliman, H. ; Jerke, U. ; N'Guessan, K. ; Dallet-Choisy, S. ; Lesner, A. ; Lauritzen, C. ; Schacher, B. ; Eickholz, P. ; Nagy, N. ; Széll, M. ; Croix, C. ; Viaud-Massuard, M.C. ; Al Farraj Aldosari, A. ; Ragunatha, S. ; Ibrahim Mostafa, M. ; Giampieri, F. ; Battino, M. ; Cornillier, H. ; Lorette, G. ; Stephan, J.L. ; Goizet, C. ; Pedersen, J. ; Gauthier, F. ; Jenne, D. ; Marchand-Adam, S. ; Chapple, I.L. ; Kettritz, R. ; Korkmaz, B.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.Yang, L. ; Kuang, H. ; Zhang, W. ; Wei, H. ; Xu, H.
Quantum dots cause acute systemic toxicity in lactating rats and growth restriction of offspring.Götzfried, J. ; Smirnova, N.F. ; Morrone, C. ; Korkmaz, B. ; Yildirim, A.Ö. ; Eickelberg, O. ; Jenne, D.
Preservation with alpha(1)-antitrypsin improves primary graft function of murine lung transplants.Kannler, M. ; Lüling, R. ; Yildirim, A.Ö. ; Gudermann, T. ; Steinritz, D. ; Dietrich, A.
TRPA1 channels: Expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia.Meiners, S. ; Evankovich, J. ; Mallampalli, R.K.
The ubiquitin proteasome system as a potential therapeutic target for systemic sclerosis.Reicherzer, T. ; Häffner, S. ; Shahzad, T. ; Gronbach, J. ; Mysliwietz, J. ; Huebener, C. ; Hasbargen, U. ; Gertheiss, J. ; Schulze, A. ; Bellusci, S. ; Morty, R.E. ; Hilgendorff, A. ; Ehrhardt, H.
Activation of the NF-kappa B pathway alters the phenotype of MSCs in the tracheal aspirates of preterm infants with severe BPD.Fritsch-Decker, S. ; Marquardt, C. ; Stöger, T. ; Diabaté, S. ; Weiss, C.
Revisiting the stress paradigm for silica nanoparticles: Decoupling of the anti-oxidative defense, pro-inflammatory response and cytotoxicity.Saxon, J.A. ; Yu, H. ; Polosukhin, V.V. ; Stathopoulos, G.T. ; Gleaves, L.A. ; McLoed, A.G. ; Massion, P.P. ; Yull, F.E. ; Zhao, Z. ; Blackwell, T.S.
P52 expression enhances lung cancer progression.Morrone, C.
Inhibition of neutrophil serine proteases by alpha 1 antitrypsin in during storage preserves primary graft functions of transplanted murine donor lungs.Gradl, R. ; Dierolf, M. ; Guenther, B. ; Hehn, L. ; Möller, W. ; Kutschke, D. ; Yang, L. ; Donnelley, M. ; Murrie, R. ; Erl, A. ; Stöger, T. ; Gleich, B. ; Achterhold, K. ; Schmid, O. ; Pfeiffer, F. ; Morgan, K.S.
In vivo dynamic phase-contrast X-ray Imaging using a compact light source.Zhang, W. ; Ohno, S. ; Steer, B. ; Klee, S. ; Staab-Weijnitz, C.A. ; Wagner, D.E. ; Lehmann, M. ; Stöger, T. ; Königshoff, M. ; Adler, H.
S100a4 is secreted by alternatively activated alveolar macrophages and promotes activation of lung fibroblasts in pulmonary fibrosis.Zhang, P. ; Ding, Z. ; Liu, X. ; Chen, Y. ; Li, J. ; Tao, Z. ; Fei, Y. ; Xue, C. ; Qian, J. ; Wang, X. ; Li, Q. ; Stöger, T. ; Chen, J. ; Bi, Y. ; Yin, R.
Enhanced replication of virulent Newcastle disease virus in chicken macrophages is due to polarized activation of cells by inhibition of TLR7.Vreka, M. ; Lilis, I. ; Papageorgopoulou, M. ; Giotopoulou, G.A. ; Lianou, M. ; Giopanou, I. ; Kanellakis, N.I. ; Spella, M. ; Agalioti, T. ; Armenis, V. ; Goldmann, T. ; Marwitz, S. ; Yull, F.E. ; Blackwell, T.S. ; Pasparakis, M. ; Marazioti, A. ; Stathopoulos, G.T.
IkB kinase a Is required for development and progression of KRAS-mutant lung adenocarcinoma.Knüppel, L. ; Heinzelmann, K. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis.Hartl, D. ; Tirouvanziam, R. ; Laval, J. ; Greene, C.M. ; Habiel, D.M. ; Sharma, L. ; Yildirim, A.Ö. ; Dela Cruz, C.S. ; Hogaboam, C.M.
Innate immunity of the lung: From basic mechanisms to translational medicine.Greiffo, F.R. ; Frankenberger, M. ; Dietel, D. ; Ortega-Gomez, A. ; Behr, J. ; Soehnlein, O. ; Fernandez, I.E. ; Eickelberg, O.
Fractalkine/CX3CR1 axis drives kinetic changes of monocytes in fibrotic Interstitial Lung Disease.Dehmel, S. ; Nathan, P. ; Bartel, S. ; El-Mehrie, N. ; Scherb, H. ; Milger, K. ; John-Schuster, G. ; Yildirim, A.Ö. ; Hyklema, M. ; Irmler, M. ; Beckers, J. ; Schaub, B. ; Eickelberg, O. ; Krauss-Etschmann, S.
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.Jiang, D. ; Correa-Gallegos, D. ; Christ, S. ; Stefanska, A. ; Liu, J. ; Ramesh, P. ; Rajendran, V. ; De Santis, M. ; Wagner, D.E. ; Rinkevich, Y.
Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring.Jia, J. ; Conlon, T.M. ; Sarker, R.S. ; Taşdemir, D. ; Smirnova, N.F. ; Srivastava, B. ; Verleden, S.E. ; Güneş, G. ; Wu, X. ; Prehn, C. ; Gao, J. ; Heinzelmann, K. ; Lintelmann, J. ; Irmler, M. ; Pfeiffer, S. ; Schloter, M. ; Zimmermann, R. ; Hrabě de Angelis, M. ; Beckers, J. ; Adamski, J. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.Guarino, C. ; Gruba, N. ; Grzywa, R. ; Dyguda-Kazimierowicz, E. ; Hamon, Y. ; Łȩgowska, M. ; Skoreński, M. ; Dallet-Choisy, S. ; Marchand-Adam, S. ; Kellenberger, C. ; Jenne, D. ; Sieńczyk, M. ; Lesner, A. ; Gauthier, F. ; Korkmaz, B.
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.Noskovicova, N. ; Heinzelmann, K. ; Burgstaller, G. ; Behr, J. ; Eickelberg, O.
Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation.Houssaini, A. ; Breau, M. ; Kebe, K. ; Abid, S. ; Marcos, E. ; Lipskaia, L. ; Rideau, D. ; Parpaleix, A. ; Huang, J. ; Amsellem, V. ; Vienney, N. ; Validire, P. ; Maitre, B. ; Attwe, A. ; Lukas, C. ; Vindrieux, D. ; Boczkowski, J. ; Derumeaux, G. ; Pende, M. ; Bernard, D. ; Meiners, S. ; Adnot, S.
mTOR pathway activation drives lung cell senescence and emphysema.Shandilya, N. ; Ligthart, T. ; van Voorde, I. ; Stahlmecke, B. ; Clavaguera, S. ; Philippot, C. ; Ding, Y. ; Goede, H.
A nanomaterial release model for waste shredding using a Bayesian belief network.Lai, T. ; Wu, M. ; Liu, J. ; Luo, M.C. ; He, L. ; Wang, X. ; Wu, B.L. ; Ying, S. ; Chen, Z. ; Li, W. ; Shen, H.
Acid-suppressive drug use during pregnancy and the risk of childhood asthma: A meta-analysis.Marazioti, A. ; Lilis, I. ; Vreka, M. ; Apostolopoulou, H. ; Kalogeropoulou, A. ; Giopanou, I. ; Giotopoulou, G.A. ; Krontira, A.C. ; Iliopoulou, M. ; Kanellakis, N.I. ; Agalioti, T. ; Giannou, A.D. ; Jones-Paris, C. ; Iwakura, Y. ; Kardamakis, D. ; Blackwell, T.S. ; Taraviras, S. ; Spella, M. ; Stathopoulos, G.T.
Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.Hellbach, K. ; Meinel, F.G. ; Conlon, T.M. ; Willer, K. ; Yaroshenko, A. ; Velroyen, A. ; Braunagel, M. ; Auweter, S. ; Reiser, M.F. ; Eickelberg, O. ; Pfeiffer, F. ; Yildirim, A.Ö.
X-ray dark-field imaging to depict acute lung inflammation in mice.Rozman, J. ; Rathkolb, B. ; Oestereicher, M.A. ; Schütt, C. ; Ravindranath, A.C. ; Leuchtenberger, S. ; Sharma, S. ; Kistler, M. ; Willershäuser, M. ; Brommage, R. ; Meehan, T.F. ; Mason, J. ; Haselimashhadi, H. ; Hough, T. ; Mallon, A.-M. ; Wells, S. ; Santos, L. ; Lelliott, C.J. ; White, J.K. ; Sorg, T. ; Champy, M.-F. ; Bower, L.R. ; Reynolds, C.L. ; Flenniken, A.M. ; Murray, S.A. ; Nutter, L.M.J. ; Svenson, K.L. ; West, D. ; Tocchini-Valentini, G.P. ; Beaudet, A.L. ; Bosch, F. ; Braun, R.B. ; Dobbie, M.S. ; Gao, X. ; Herault, Y. ; Moshiri, A. ; Moore, B.A. ; Kent Lloyd, K.C. ; McKerlie, C. ; Masuya, H. ; Tanaka, N. ; Flicek, P. ; Parkinson, H.E. ; Sedlacek, R. ; Seong, J.K. ; Wang, C.-K.L. ; Moore, M. ; Brown, S.D. ; Tschöp, M.H. ; Wurst, W. ; Klingenspor, M. ; Wolf, E. ; Beckers, J. ; Machicao, F. ; Peter, A. ; Staiger, H. ; Häring, H.-U. ; Grallert, H. ; Campillos, M. ; Maier, H. ; Fuchs, H. ; Gailus-Durner, V. ; Werner, T. ; Hrabě de Angelis, M. ; IMPC Consortium (Eickelberg, O.) ; IMPC Consortium (Yildirim, A.Ö.)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Burgstaller, G. ; Sengupta, A. ; Vierkotten, S. ; Preissler, G. ; Lindner, M. ; Behr, J. ; Königshoff, M. ; Eickelberg, O.
Distinct niches within the extracellular matrix dictate fibroblast function in (cell free) 3D lung tissue cultures.Maldonado, M. ; Salgado-Aguayo, A. ; Herrera, I. ; Cabrera, S. ; Ortíz-Quintero, B. ; Staab-Weijnitz, C.A. ; Eickelberg, O. ; Ramírez, R. ; Manicone, A.M. ; Selman, M. ; Pardo, A.
Upregulation and nuclear location of MMP28 in alveolar epithelium of idiopathic pulmonary fibrosis.Smirnova, N.F. ; Eickelberg, O.
Epithelial progenitor cells take center stage in lung transplantation.Skronska-Wasek, W. ; Gosens, R. ; Königshoff, M. ; Baarsma, H.A.
WNT receptor signalling in lung physiology and pathology.Zscheppang, K. ; Berg, J.V. ; Hedtrich, S. ; Verheyen, L. ; Wagner, D.E. ; Suttorp, N. ; Hippenstiel, S. ; Hocke, A.C.
Human pulmonary 3D models for translational research.Förster, K. ; Sass, S. ; Ehrhardt, H. ; Mous, D.S. ; Rottier, R.J. ; Oak, P. ; Schulze, A. ; Flemmer, A.W. ; Gronbach, J. ; Hübener, C. ; Desai, T. ; Eickelberg, O. ; Theis, F.J. ; Hilgendorff, A.
Early identification of bronchopulmonary dysplasia using novel biomarkers by proteomic screening.Borry, P. ; Bentzen, H.B. ; Budin-Ljøsne, I. ; Cornel, M.C. ; Howard, H.C. ; Feeney, O. ; Jackson, L. ; Mascalzoni, D. ; Mendes, Á. ; Peterlin, B. ; Riso, B. ; Shabani, M. ; Skirton, H. ; Sterckx, S. ; Vears, D. ; Wjst, M. ; Felzmann, H.
The challenges of the expanded availability of genomic information: An agenda-setting paper.Kostric, M. ; Milger, K. ; Krauss-Etschmann, S. ; Engel, M. ; Vestergaard, G. ; Schloter, M. ; Schöler, A.
Development of a stable lung microbiome in healthy neonatal mice.Leuschner, G. ; Stocker, F. ; Veit, T. ; Kneidinger, N. ; Winter, H. ; Schramm, R. ; Weig, T. ; Matthes, S. ; Ceelen, F. ; Arnold, P. ; Munker, D. ; Klenner, F. ; Hatz, R. ; Frankenberger, M. ; Behr, J. ; Neurohr, C.
Outcome of lung transplantation in idiopathic pulmonary fibrosis with previous anti-fibrotic therapy.