Publications
Förster, K. ; Frank, A. ; Ehrhardt, H. ; Hilgendorff, A.
Neue diagnostische Werkzeuge für die frühzeitige Identifikation und strukturelle Charakterisierung der Bronchopulmonalen Dysplasie.Ramsheh, M.Y. ; Thun, G.A. ; Codina, A.E. ; Haldar, K. ; Barer, M. ; Gut, I. ; Ziegler-Heitbrock, L. ; Singh, D. ; Brightling, C.
Prevotella genera abundance in bronchial brush samples differentiates COPD from health and is associated with gene expression.Ramsheh, M.Y. ; Haldar, K. ; Barer, M. ; Ziegler-Heitbrock, L. ; Gut, I. ; Singh, D. ; Brightling, C.
Association between COPD bronchial brush microbiome-determined ?Proteobacteria:Firmicutes (G:F) ratio and GOLD grade and symptoms.Wolff, M. ; El-Merhie, N. ; Reuter, S. ; Goldmann, T. ; Yildirim, A.Ö. ; Fehrenbach, H. ; Krauss-Etschmann, S.
LSC-2019-Relevant murine model to study the development of COPD pathogenesis in smokers with viral infections.Gonzalez, E. ; Zhang, X. ; Oak, P. ; Markmann, M. ; Hilgendorff, A.
Hyperoxia exposure induces age-dependent changes in gene expression in healthy mouse lung.Lehmann, M. ; Mutze, K. ; Hu, Q. ; Königshoff, M.
Late Breaking Abstract - WNT/beta-catenin signaling induces cellular senescence in lung alveolar epithelial cells.Zhang, X. ; Rodriguez, E. ; Markmann, M. ; Oak, P. ; Hilgendorff, A.
Expression profiling of genes differentially regulated under hyperoxia andmechanical ventilation in mouse model of neonatal chronic lung disease.Hardy, S. ; Schneider, A. ; Frankenberger, M. ; Koch, A. ; Milger, K. ; Moulin, C. ; Fievez, M. ; Pilette, C. ; Meiners, S. ; Kammerl, I.E.
LSC-2019-Validating immunoproteasome activity as a potential biomarker in non-invasive samples from COPD patients.Chen, J. ; Brands, J. ; Bueno, M. ; Adler, H. ; Mora, A. ; Meiners, S. ; Kammerl, I.E.
LSC-2019-Effect of cigarette smoke on immunoproteasome function during virus infection.Cyrys, J. ; Schnelle-Kreis, J. ; Kowalski, M. ; Yildirim, A.Ö. ; Schmid, O. ; Stöger, T. ; Peters, A. ; Schneider, A.E. ; Pickford, R. ; Zhang, S. ; Breitner-Busch, S.
Ambient ultrafine particles: Evidence for policy maker.Meul, T. ; Wang, X. ; Angelidis, I. ; Berschneider, K. ; Schmitt, S. ; Zischka, H. ; von Toerne, C. ; Hauck, S.M. ; Schiller, H. B. ; Meiners, S.
Mitochondrial dysfunction activates MHC class I adaptive immune responses in lung aging.Behr, J. ; Wirtz, H. ; Pittrow, D. ; Prasse, A. ; Koschel, D. ; Geier, S. ; Klotsche, J. ; Andreas, S. ; Claussen, M. ; Grohe, C. ; Wilkens, H. ; Hagmeyer, L. ; Skowasch, D. ; Meyer, J.F. ; Kirschner, J. ; Glaeser, S. ; Kahn, N. ; Welte, T. ; Neurohr, C. ; Schwaiblmair, M. ; Held, M. ; Bahmer, T. ; Oqueka, T. ; Frankenberger, M. ; Kreuter, M.
Late Breaking Abstract - Survival and course of lung function in patients with idiopathic pulmonary fibrosis with or without antifibrotic treatment: Long-term results of the INSIGHTS-IPF registry.Morgan, K.S. ; Gradl, R. ; Dierolf, M. ; Jud, C. ; Günther, B. ; Werdiger, F. ; Gardner, M. ; Cmielewski, P. ; McCarron, A. ; Farrow, N. ; Haas, H. ; Kimm, M.A. ; Yang, L. ; Kutschke, D. ; Stöger, T. ; Schmid, O. ; Achterhold, K. ; Pfeiffer, F. ; Parsons, D. ; Donnelley, M.
In vivo x-ray imaging of the respiratory system using synchrotron sources and a compact light source.Thun, G.A. ; Derdak, S. ; Castro-Giner, F. ; Apunte-Ramos, K. ; Águeda, L. ; Wjst, M. ; Boland, A. ; Deleuze, J.F. ; Kolsum, U. ; Heiss-Neumann, M.S. ; Nowinski, A. ; Gorecka, D. ; Hohlfeld, J.M. ; Welte, T. ; Brightling, C.E. ; Parr, D.G. ; Prasse, A. ; Müller-Quernheim, J. ; Greulich, T. ; Stendardo, M. ; Boschetto, P. ; Barta, I. ; Döme, B. ; Gut, M. ; Singh, D. ; Ziegler-Heitbrock, L. ; Gut, I.G.
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.Ulke, H.M. ; Mutze, K. ; Lehmann, M. ; Wagner, D.E. ; Heinzelmann, K. ; Guenther, A. ; Eickelberg, O. ; Königshoff, M.
The oncogene ECT2 contributes to a hyperplastic, proliferative lung epithelial cell phenotype in idiopathic pulmonary fibrosis.Correa-Gallegos, D. ; Jiang, D. ; Christ, S. ; Ramesh, P. ; Ye, H. ; Wannemacher, J. ; Kalgudde Gopal, S. ; Yu, Q. ; Aichler, M. ; Walch, A.K. ; Mirastschijski, U. ; Volz, T. ; Rinkevich, Y.
Patch repair of deep wounds by mobilized fascia.Doll, S. ; Freitas, F.P. ; Shah, R. ; Aldrovandi, M. ; da Silva, M.C. ; Ingold, I. ; Grocin, A.G. ; Xavier da Silva, T.N. ; Panzilius, E. ; Scheel, C. ; Mourao, A. ; Buday, K. ; Sato, M. ; Wanninger, J. ; Vignane, T. ; Mohana, V. ; Rehberg, M. ; Flatley, A. ; Schepers, A. ; Kurz, A. ; White, D. ; Sauer, M. ; Sattler, M. ; Tate, E.W. ; Schmitz, W. ; Schulze, A. ; O’Donnell, V. ; Proneth, B. ; Popowicz, G.M. ; Pratt, D.A. ; Angeli, J.P.F. ; Conrad, M.
FSP1 is a glutathione-independent ferroptosis suppressor.Ramsheh, M.Y. ; Haldar, K. ; Bafadhel, M. ; George, L. ; Free, R.C. ; John, C. ; Reeve, N.F. ; Ziegler-Heitbrock, L. ; Gut, I. ; Singh, D. ; Mistry, V. ; Tobin, M.D. ; Oggioni, M.R. ; Brightling, C. ; Barer, M.R.
Resistome analyses of sputum from COPD and healthy subjects reveals bacterial load-related prevalence of target genes.Giopanou, I. ; Kanellakis, N.I. ; Giannou, A.D. ; Lilis, I. ; Marazioti, A. ; Spella, M. ; Papaleonidopoulos, V. ; Simoes, D.C.M. ; Zazara, D.E. ; Agalioti, T. ; Moschos, C. ; Magkouta, S. ; Kalomenidis, I. ; Panoutsakopoulou, V. ; Lamort, A.-S. ; Stathopoulos, G.T.
Osteopontin drives KRAS-mutant lung adenocarcinoma.Holzwarth, U. ; Cossio, U. ; Llop, J. ; Kreyling, W.G.
Unpredictable nanoparticle retention in commonly used plastic syringes introduces dosage uncertainties that may compromise the accuracy of nanomedicine and nanotoxicology studies.Gulbake, A.S. ; Jain, A. ; Shilpi, S. ; Kumar, P. ; Gulbake, A.
Mannosylated multiwalled carbon nanotubes assisted artesunate delivery for cerebral malaria.Kesireddy, V.S. ; Chillappagari, S. ; Ahuja, S. ; Knudsen, L. ; Henneke, I. ; Graumann, J. ; Meiners, S. ; Ochs, M. ; Ruppert, C. ; Korfei, M. ; Seeger, W. ; Mahavadi, P.
Susceptibility of microtubule-associated protein 1 light chain 3 beta (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.Pang, Y.P. ; Moura, M.C. ; Thompson, G.E. ; Nelson, D.R. ; Hummel, A.M. ; Jenne, D. ; Emerling, D. ; Volkmuth, W. ; Robinson, W.H. ; Specks, U.
Remote activation of a latent epitope in an autoantigen decoded with simulated B-factors.Sarker, R.S. ; Conlon, T.M. ; Morrone, C. ; Srivastava, B. ; Konyalilar, N. ; Verleden, S.E. ; Bayram, H. ; Fehrenbach, H. ; Yildirim, A.Ö.
CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis.Distler, J.H.W. ; Györfi, A.H. ; Ramanujam, M. ; Whitfield, M.L. ; Königshoff, M. ; Lafyatis, R.
Shared and distinct mechanisms of fibrosis.Andrault, P.-M. ; Schamberger, A.C. ; Chazeirat, T. ; Sizaret, D. ; Renault, J. ; Staab-Weijnitz, C.A. ; Hennen, E. ; Petit-Courty, A. ; Wartenberg, M. ; Saidi, A. ; Baranek, T. ; Guyetant, S. ; Courty, Y. ; Eickelberg, O. ; Lalmanach, G. ; Lecaille, F.
Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD.Alhasan, M. ; Cait, A. ; Heimesaat, M.M. ; Blaut, M. ; Klopfleisch, R. ; Yildirim, A.Ö. ; Sodemann, E.B. ; Bereswill, S. ; Conrad, M.L.
Antibiotic use during pregnancy impacts neonatal microbiota composition and increases offspring asthma severity.Arendt, K.A.M. ; Ntaliarda, G. ; Armenis, V. ; Stathopoulos, G.T.
An in vivo inflammatory loop potentiates KRAS blockade.Oplopoiou, M. ; Kati, D. ; Ntaliarda, G. ; Papaleonidopoulos, V. ; Giopanou, I. ; Lilis, I. ; Stathopoulos, G.T.
The role of Trp53 in chemical-induced lung adenocarcinoma.Welk, V. ; Meul, T. ; Lukas, C. ; Kammerl, I.E. ; Mulay, S.R. ; Schamberger, A.C. ; Semren, N. ; Fernandez, I.E. ; Anders, H.J. ; Günther, A. ; Behr, J. ; Eickelberg, O. ; Korfei, M. ; Meiners, S.
Proteasome activator PA200 regulates myofibroblast differentiation.Yang, L. ; Gradl, R. ; Dierolf, M. ; Möller, W. ; Kutschke, D. ; Feuchtinger, A. ; Hehn, L. ; Donnelley, M. ; Günther, B. ; Achterhold, K. ; Walch, A.K. ; Stöger, T. ; Razansky, D. ; Pfeiffer, F. ; Morgan, K.S. ; Schmid, O.
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.Umkehrer, S. ; Birnbacher, L. ; Burkhardt, R. ; Von Teuffenbach, M. ; Yildirim, A.Ö. ; Pfeiffer, D. ; Herzen, J. ; Pfeiffer, F.
Optimization of in vivo murine X-ray dark-field computed tomography.Wang, X. ; Chen, S. ; Ren, H. ; Chen, J. ; Li, J. ; Wang, Y. ; Hua, Y. ; Wang, X. ; Huang, N.
HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization.Tsai, J.M. ; Shoham, M. ; Fernhoff, N.B. ; George, B.M. ; Marjon, K.D. ; McCracken, M.N. ; Kao, K.S. ; Sinha, R. ; Volkmer, A.K. ; Miyanishi, M. ; Seita, J. ; Rinkevich, Y. ; Weissman, I.L.
Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation.Marazioti, A. ; Papadia, K. ; Kannavou, M. ; Spella, M. ; Basta, A. ; de Lastic, A.L. ; Rodi, M. ; Mouzaki, A. ; Samiotaki, M. ; Panayotou, G. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Cellular vesicles: New insights in engineering methods, interaction with cells and potential for brain targeting.Lamort, A.-S. ; Hamon, Y. ; Czaplewski, C. ; Gieldon, A. ; Seren, S. ; Coquet, L. ; Lecaille, F. ; Lesner, A. ; Lalmanach, G. ; Gauthier, F. ; Jenne, D. ; Korkmaz, B.
Processing and maturation of cathepsin C zymogen: A biochemical and molecular modeling analysis.Wang, H. ; Wei, Y. ; Pu, Y. ; Jiang, D. ; Jiang, X. ; Zhang, Y. ; Tao, J.
Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity.Thompson, G. ; Moura, M.C. ; Nelson, D. ; Fussner, L. ; Hummel, A. ; Jenne, D. ; Fervenza, F. ; Hoffman, G. ; Kallenberg, C. ; Langford, C. ; McCune, J. ; Merkel, P. ; Monach, P. ; Seo, P. ; Spiera, R. ; St Clair, E.W. ; Ytterberg, S. ; Stone, J. ; Robinson, W. ; Pang, Y. ; Specks, U.
Preferential binding to an unexpected epitope of a chimeric recombinant proteinase 3 variant by anti-neutrophil cytoplasmic antibodies.Lamort, A.-S. ; Giopanou, I. ; Psallidas, I. ; Stathopoulos, G.T.
Osteopontin as a link between inflammation and cancer: The thorax in the spotlight.Fei, Y. ; Liu, X. ; Mu, J. ; Li, J. ; Yu, X. ; Chang, J. ; Bi, Y. ; Stöger, T. ; Wajid, A. ; Muzyka, D. ; Sharshov, K. ; Shestopalov, A. ; Amonsin, A. ; Chen, J. ; Ding, Z. ; Yin, R.
The emergence of avian orthoavulavirus 13 in wild migratory waterfowl in China revealed the existence of diversified trailer region sequences and HN gene lengths within this serotype.Zhu, Y. ; Cao, Z. ; Peng, Y. ; Hu, L. ; Güney, T. ; Tang, B.
Facile surface modification method for synergistically enhancing the biocompatibility and bioactivity of poly(ether ether ketone) that induced osteodifferentiation.Nikolić, M.Z. ; Garrido-Martin, E.M. ; Greiffo, F.R. ; Fabre, A. ; Heijink, I.H. ; Boots, A. ; Greene, C.M. ; Hiemstra, P.S. ; Bartel, S.
From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 "Basic and Translational Science.".Doryab, A. ; Tas, S. ; Taskin, M.B. ; Yang, L. ; Hilgendorff, A. ; Groll, J. ; Wagner, D.E. ; Schmid, O.
Evolution of bioengineered lung models: Recent advances and challenges in tissue mimicry for studying the role of mechanical forces in cell biology.Merl-Pham, J. ; Basak, T. ; Knüppel, L. ; Ramanujam, D. ; Athanason, M. ; Behr, J. ; Engelhardt, S. ; Eickelberg, O. ; Hauck, S.M. ; Vanacore, R. ; Staab-Weijnitz, C.A.
Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro model of lung fibrosis.Förster, K. ; Herber-Jonat, S. ; Florian, A. ; Klemme, M. ; Flemmer, A.W.
Langzeitentwicklung von Kindern nach Extra Corporaler Membran Oxygenierung (ECMO).Ng-Blichfeldt, J.P. ; de Jong, T. ; Kortekaas, R.K. ; Wu, X. ; Lindner, M. ; Guryev, V. ; Hiemstra, P.S. ; Stolk, J. ; Königshoff, M. ; Gosens, R.
TGF-beta activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.Kreyling, W.G. ; Holzwarth, U. ; Schleh, C. ; Hirn, S. ; Wenk, A. ; Schäffler, M. ; Haberl, N. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics over a 28day period of freshly generated, pristine, 20 nm titanium dioxide nanoparticle aerosols in healthy adult rats after a single two-hour inhalation exposure.Rehm, S.R.T. ; Smirnova, N.F. ; Morrone, C. ; Götzfried, J. ; Feuchtinger, A. ; Pedersen, J. ; Korkmaz, B. ; Yildirim, A.Ö. ; Jenne, D.
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.Fernandez, I.M. ; Macrini, C. ; Krumbholz, M. ; Hensbergen, P.J. ; Ederveen, A.L.H. ; Winklmeier, S. ; Vural, A. ; Kurne, A. ; Jenne, D. ; Kamp, F. ; Gerdes, L.A. ; Hohlfeld, R. ; Wuhrer, M. ; Kuempfel, T. ; Meinl, E.
The glycosylation site of myelin oligodendrocyte glycoprotein affects autoantibody recognition in a large proportion of patients.Gradl, R. ; Dierolf, M. ; Yang, L. ; Hehn, L. ; Günther, B. ; Möller, W. ; Kutschke, D. ; Stöger, T. ; Gleich, B. ; Achterhold, K. ; Donnelley, M. ; Pfeiffer, F. ; Schmid, O. ; Morgan, K.S.
Visualizing treatment delivery and deposition in mouse lungs using in vivo x-ray imaging.Yu, S. ; Zhang, Y. ; Zhao, X. ; Chang, Z. ; Wei, Y. ; Sun, Y. ; Jiang, D. ; Jiang, X. ; Tao, J.
Cholecystokinin type B receptor-mediated inhibition of A-type K+ channels enhances sensory neuronal excitability through the phosphatidylinositol 3-kinase and c-Src-dependent JNK pathway.Farnoud, A. ; Orak, S. ; Schmid, O.
Numerical models of respiratory drug deposition and pharmacokinetics: Application to liposomal ciclosporin a (L-CSA).Schmid, O.
Advanced in vitro and in silico models improve predictions of in vivo/clinical pharmacokinetics of nanocarrier-laden inhaled drugs.Yang, L. ; Gradl, R. ; Feuchtinger, A. ; Morgan, K.S. ; Kutschke, D. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Pfeiffer, F. ; Schmidt, O.
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.Klotz, L.V. ; Lindner, M. ; Eichhorn, M.E. ; Grützner, U. ; Koch, I. ; Winter, H. ; Kauke, T. ; Duell, T. ; Hatz, R.
Pleurectomy/decortication and hyperthermic intrathoracic chemoperfusion using cisplatin and doxorubicin for malignant pleural mesothelioma.Orak, S. ; Rothen-Rutishauser, B. ; Jud, C. ; Farnoud, A. ; Bucholski, A. ; Egle, R. ; Boerner, G. ; Denk, O. ; Schmid, O.
Towards prediction of the pharmacokinetics of inhaled nanomedicine from physiological cell models: A case study with liposomal ciclosporin A (L-CSA) using the vitrocell cloud system.Marazioti, A. ; Papadia, K. ; Giannou, A. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection.Merrick, C. ; Sherrill, T. ; Kanellakis, N.I. ; Asciak, R. ; Stathopoulos, G.T. ; Maldonado, F. ; Rahman, N.M. ; Blackwell, T. ; Psallidas, I.
Novel mouse model of indwelling pleural catheter in mice with malignant pleural effusion.Spella, M. ; Lilis, I. ; Pepe, M. ; Chen, Y. ; Armaka, M. ; Lamort, A.-S. ; Zazara, D.E. ; Roumelioti, F. ; Vreka, M. ; Kanellakis, N.I. ; Wagner, D.E. ; Giannou, A.D. ; Armenis, V. ; Arendt, K.A.M. ; Klotz, L.V. ; Toumpanakis, D. ; Karavana, V. ; Zakynthinos, S.G. ; Giopanou, I. ; Marazioti, A. ; Aidinis, V. ; Sotillo, R. ; Stathopoulos, G.T.
Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.Conlon, T.M. ; Güneş, G. ; Sarker, R.S. ; Fehrenbach, H. ; Yildirim, A.Ö.
Arginine methylation epigenetically regulates airway epithelial cell injury in COPD pathogenesis.Srivastava, B. ; Conlon, T.M. ; Mitula, E. ; Sarker, R.S. ; Yildirim, A.Ö.
Developing oxysterol inhibitors as a novel therapeutic target for iBALT driven chronic pulmonary diseases.Gunsel, G.G. ; Conlon, T.M. ; Sarker, R. ; Jia, J. ; Heinzelmann, K. ; Tasdemir, D. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Metabolomic regulation of B cells drives the pathogenesis of COPD.Staab-Weijnitz, C.A. ; Merl-Pham, J. ; Basak, T. ; Knüppel, L. ; Ramanujam, D. ; Athanason, M. ; Behr, J. ; Engelhardt, S. ; Eickelberg, O. ; Hauck, S.M. ; Vanacore, R.
Quantitative proteomic profiling of extracellular matrix and collagen posttranslational modifications in an in vitro model of lung fibrosis.Heinzelmann, K. ; Ulke, H.M. ; Mutze, K. ; Wagner, D.E. ; Ren, W. ; Guenther, A. ; Eickelberg, O. ; Koenigshoff, M.
Epithelial cell transforming sequence 2 contributes to alveolar epithelial cell reprogramming in idiopathic pulmonary fibrosis.Fernandez, I.E. ; Greiffo, F.R. ; Viteri-Alvarez, V. ; Bastidas, I. ; Roy, R. ; Frankenberger, M. ; Behr, J. ; Forrest, A. ; Hilgendorff, A. ; Eickelberg, O.
Myeloid-derived suppressor cells orchestrate immunosuppressive networks in idiopathic pulmonary fibrosis.Lehmann, M. ; Klee, S. ; Wagner, D.E. ; Koenigshoff, M.
Wnt1-inducible signaling protein 1 (WISP1) augments nuclear factor (NF)-kB signaling in primary human lung fibroblasts.Bölükbas, D.A. ; Morrone, C. ; Doryab, A. ; Datz, S. ; Gößl, D. ; Meyer-Schwickerath, C. ; Vreka, M. ; van Rijt, S.H. ; Stöger, T. ; Stathopoulos, G.T. ; Lindstedt, S. ; Bein, T. ; Meiners, S. ; Wagner, D.E.
Fine-tuning lung cancer nanotherapy using closed cardiopulmonary circulation.Halappanavar, S. ; Rahman, L. ; Nikota, J. ; Poulsen, S.S. ; Ding, Y. ; Jackson, P. ; Wallin, H. ; Schmid, O. ; Vogel, U. ; Williams, A.
Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses.Moore, C. ; Blumhagen, R.Z. ; Yang, I.V. ; Walts, A. ; Powers, J. ; Walker, T. ; Bishop, M. ; Russell, P. ; Vestal, B. ; Cardwell, J. ; Markin, C.R. ; Mathai, S.K. ; Schwarz, M.I. ; Steele, M.P. ; Lee, J. ; Brown, K.K. ; Loyd, J.E. ; Crapo, J.D. ; Silverman, E.K. ; Cho, M.H. ; James, J.A. ; Guthridge, J.M. ; Cogan, J.D. ; Kropski, J.A. ; Swigris, J.J. ; Bair, C. ; Soon Kim, D. ; Ji, W. ; Kim, H. ; Song, W.J. ; Maier, L.A. ; Pacheco, K.A. ; Hirani, N. ; Poon, A.S. ; Li, F. ; Jenkins, R.G. ; Braybrooke, R. ; Saini, G. ; Maher, T.M. ; Molyneaux, P.L. ; Saunders, P. ; Zhang, Y. ; Gibson, K.F. ; Kass, D.J. ; Rojas, M. ; Sembrat, J. ; Wolters, P.J. ; Collard, H.R. ; Sundy, J.S. ; O'Riordan, T. ; Strek, M.E. ; Noth, I. ; Ma, S.F. ; Porteous, M.K. ; Kreider, M.E. ; Patel, N.B. ; Inoue, Y. ; Hirose, M. ; Arai, T. ; Akagawa, S. ; Eickelberg, O. ; Fernandez, I.E. ; Behr, J. ; Mogulkoc, N. ; Corte, T.J. ; Glaspole, I. ; Tomassetti, S. ; Ravaglia, C. ; Poletti, V. ; Crestani, B. ; Borie, R. ; Kannengiesser, C. ; Parfrey, H. ; Fiddler, C. ; Rassl, D. ; Molina-Molina, M. ; Machahua, C. ; Montes Worboys, A. ; Gudmundsson, G. ; Isaksson, H.J. ; Lederer, D.J. ; Podolanczuk, A.J. ; Montesi, S.B. ; Bendstrup, E. ; Danchel, V. ; Selman, M. ; Pardo, A. ; Henry, M.T. ; Keane, M.P. ; Doran, P. ; Vašáková, M. ; Sterclova, M. ; Ryerson, C.J. ; Wilcox, P.G. ; Okamoto, T. ; Furusawa, H. ; Miyazaki, Y. ; Laurent, G. ; Baltic, S. ; Prele, C. ; Moodley, Y. ; Shea, B.S. ; Ohta, K. ; Suzukawa, M. ; Narumoto, O. ; Nathan, S.D. ; Venuto, D.C. ; Woldehanna, M.L. ; Kokturk, N. ; de Andrade, J.A. ; Luckhardt, T. ; Kulkarni, T. ; Bonella, F. ; Donnelly, S.C. ; McElroy, A. ; Armstrong, M.E. ; Aranda, A. ; Carbone, R.G. ; Puppo, F. ; Beckman, K.B. ; Nickerson, D.A. ; Fingerlin, T.E. ; Schwartz, D.A.
Resequencing study confirms host defense and cell senescence gene variants contribute to the risk of idiopathic pulmonary fibrosis.Ballester-Lopez, C. ; Conlon, T.M. ; Ertüz, Z. ; Greiffo, F.R. ; Irmler, M. ; Verleden, S.E. ; Beckers, J. ; Fernandez, I.E. ; Eickelberg, O. ; Yildirim, A.Ö.
The Notch ligand DNER regulates macrophage IFN gamma release in chronic obstructive pulmonary disease.Modic, M. ; Grosch, M. ; Rot, G. ; Schirge, S. ; Lepko, T. ; Yamazaki, T. ; Lee, F.C.Y. ; Rusha, E. ; Shaposhnikov, D. ; Palo, M. ; Merl-Pham, J. ; Cacchiarelli, D. ; Rogelj, B. ; Hauck, S.M. ; von Mering, C. ; Meissner, A. ; Lickert, H. ; Hirose, T. ; Ule, J. ; Drukker, M.
Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition.Mascalzoni, D. ; Bentzen, H.B. ; Budin-Ljøsne, I. ; Bygrave, L.A. ; Bell, J. ; Dove, E.S. ; Fuchsberger, C. ; Hveem, K. ; Mayrhofer, M.T. ; Meraviglia, V. ; O'Brien, D.R. ; Pattaro, C. ; Pramstaller, P.P. ; Rakic, V. ; Rossini, A. ; Shabani, M. ; Svantesson, D.J.B. ; Tomasi, M. ; Ursin, L. ; Wjst, M. ; Kaye, J.
Are requirements to deposit data in research repositories compatible with the european union's general data protection regulation?Lilis, I. ; Ntaliarda, G. ; Papaleonidopoulos, V. ; Giotopoulou, G.A. ; Oplopoiou, M. ; Marazioti, A. ; Spella, M. ; Marwitz, S. ; Goldmann, T. ; Bravou, V. ; Giopanou, I. ; Stathopoulos, G.T.
Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma.Wjst, M.
We are still confused but on a higher level.Vetrivel, S. ; Tiso, N. ; Kügler, A. ; Irmler, M. ; Horsch, M. ; Beckers, J. ; Hladik, D. ; Giesert, F. ; Gailus-Durner, V. ; Fuchs, H. ; Sabrautzki, S. ; Adler, T. ; Treise, I. ; Busch, D.H. ; Aguilar-Pimentel, J.A. ; Ollert, M. ; Götz, A. ; Amarie, O.V. ; Stöger, T. ; Schulz, H. ; Becker, L. ; Klopstock, T. ; Schrewe, A. ; Spielmann, N. ; Bekeredjian, R. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Mayer-Kuckuk, P. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Neff, F. ; da Silva Buttkus, P. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Prehn, C. ; Adamski, J. ; Östereicher, M.A. ; Miller, G. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Hrabě de Angelis, M. ; Graw, J.
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.Kerdidani, D. ; Chouvardas, P. ; Arjo, A.R. ; Giopanou, I. ; Ntaliarda, G. ; Guo, Y.A. ; Tsikitis, M. ; Kazamias, G. ; Potaris, K. ; Stathopoulos, G.T. ; Zakynthinos, S. ; Kalomenidis, I. ; Soumelis, V. ; Kollias, G. ; Tsoumakidou, M.
Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma.Morrone, C. ; Smirnova, N.F. ; Kneidinger, N. ; Schiller, H. B. ; Eickelberg, O. ; Yildirim, A.Ö.
Elevetad cysteine-protease activity in bronchiolitis obliterans syndrome.Jiang, D. ; Christ, S. ; Gallegos, D.C. ; Ramesh, P. ; Gopal, S.K. ; Yu, Q. ; Mayr, C. ; Lupperger, V. ; Liu, J. ; Marr, C. ; Schiller, H. B. ; Rinkevich, Y.
Visualizing scar development in living tissues reveals the collective migration of fibroblasts mediated by N-cadherin.Castelletti, N. ; Kaiser, J.C. ; Simonetto, C. ; Furukawa, K. ; Küchenhoff, H. ; Stathopoulos, G.T.
Risk of lung adenocarcinoma from smoking and radiation arises in distinct molecular pathways.Gerckens, M. ; Alsafadi, H.N. ; Wagner, D.E. ; Lindner, M. ; Burgstaller, G. ; Königshoff, M.
Generation of human 3D lung tissue cultures (3D-LTCs) for disease modeling.Kanellakis, N.I. ; Giannou, A.D. ; Pepe, M. ; Αgalioti, T. ; Zazara, D.E. ; Giopanou, I. ; Psallidas, I. ; Spella, M. ; Μarazioti, A. ; Arendt, K.A.M. ; Lamort, A.-S. ; Tsaniras, S.C. ; Taraviras, S. ; Papadaki, H. ; Lilis, I. ; Stathopoulos, G.T.
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.Kunze, F.A. ; Bauer, M. ; Komuczki, J. ; Lanzinger, M. ; Gunasekera, K. ; Hopp, A.K. ; Lehmann, M. ; Becher, B. ; Müller, A. ; Hottiger, M.O.
ARTD1 in myeloid cells controls the IL-12/18-IFN-γ axis in a model of sterile sepsis, chronic bacterial infection, and cancer.Klotz, L.V. ; Courty, Y. ; Lindner, M. ; Petit-Courty, A. ; Stowasser, A. ; Koch, I. ; Eichhorn, M.E. ; Lilis, I. ; Morresi-Hauf, A. ; Arendt, K.A.M. ; Pepe, M. ; Giopanou, I. ; Ntaliarda, G. ; Behrend, S.J. ; Oplopoiou, M. ; Gissot, V. ; Guyetant, S. ; Marchand-Adam, S. ; Behr, J. ; Kaiser, J.C. ; Hatz, R.A. ; Lamort, A.-S. ; Stathopoulos, G.T.
Comprehensive clinical profiling of the Gauting locoregional lung adenocarcinoma donors.Krampitz, G.W. ; Tsai, J. ; Norton, J.A. ; Weissman, I.L. ; Rinkevich, Y.
Adhesions are derived from hypoxia responsive mesothelin-positive mesothelial cells and are resolved via targeted therapies.Bölükbas, D.A. ; De Santis, M.M. ; Alsafadi, H.N. ; Doryab, A. ; Wagner, D.E.
The preparation of decellularized mouse lung matrix scaffolds for analysis of lung regenerative cell potential.Smirnova, N.F. ; Conlon, T.M. ; Morrone, C. ; Dorfmuller, P. ; Humbert, M. ; Stathopoulos, G.T. ; Umkehrer, S. ; Pfeiffer, F. ; Yildirim, A.Ö. ; Eickelberg, O.
Inhibition of B cell–dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation.Zhang, Y. ; Jiang, D. ; Li, H. ; Sun, Y. ; Jiang, X. ; Gong, S. ; Qian, Z. ; Tao, J.
Melanocortin type 4 receptor-mediated inhibition of A-type K+ current enhances sensory neuronal excitability and mechanical pain sensitivity in rats.Hsiao, I.L. ; Fritsch-Decker, S. ; Leidner, A. ; Al-Rawi, M. ; Hug, V. ; Diabaté, S. ; Grage, S.L. ; Meffert, M. ; Stöger, T. ; Gerthsen, D. ; Ulrich, A.S. ; Niemeyer, C.M. ; Weiss, C.
Biocompatibility of amine-functionalized silica nanoparticles: The role of surface coverage.Angelidis, I. ; Simon, L. ; Fernandez, I.E. ; Strunz, M. ; Mayr, C. ; Greiffo, F.R. ; Tsitsiridis, G. ; Ansari, M. ; Graf, E. ; Strom, T.M. ; Nagendran, M. ; Desai, T. ; Eickelberg, O. ; Mann, M. ; Theis, F.J. ; Schiller, H. B.
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics.von Siemens, S.M. ; Jörres, R.A. ; Behr, J. ; Alter, P. ; Lutter, J. ; Lucke, T. ; Söhler, S. ; Welte, T. ; Watz, H. ; Vogelmeier, C.F. ; Trudzinski, F. ; Rief, W. ; Herbig, B. ; Kahnert, K.
Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: Results from the COSYCONET cohort study.Stöger, T. ; Adler, H.
"Novel" triggers of herpesvirus reactivation and their potential health relevance.Kylafis, G.F. ; Sleigh, P.A. ; Tomlin, A.S. ; Ding, Y.
Evacuation characteristics of released airborne TiO2 nanomaterial particles under different ventilation rates in a confined environment.Kammerl, I.E. ; Caniard, A. ; Merl-Pham, J. ; Ben-Nissan, G. ; Mayr, C.H. ; Mossina, A. ; Geerlof, A. ; Eickelberg, O. ; Hauck, S.M. ; Sharon, M. ; Meiners, S.
Dissecting the molecular effects of cigarette smoke on proteasome function.Yang, L. ; Feuchtinger, A. ; Möller, W. ; Ding, Y. ; Kutschke, D. ; Möller, G. ; Schittny, J.C. ; Burgstaller, G. ; Hofmann, W. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Schmid, O.
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.Yamano, T. ; Steinert, M. ; Steer, B. ; Klein, L. ; Hammerschmidt, W. ; Adler, H.
B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?Lau, M.Y.Z. ; Dharmage, S.C. ; Burgess, J.A. ; Win, A.K. ; Lowe, A.J. ; Lodge, C.J. ; Perret, J. ; Hui, J. ; Thomas, P.S. ; Giles, G. ; Thompson, B.R. ; Abramson, M.J. ; Walters, E.H. ; Matheson, M.C. ; Collaboration (Wjst, M.)
Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization.Gao, C. ; Ding, Z. ; Qian, J. ; Liu, X. ; Zhang, X. ; Cong, Y. ; Ding, C. ; Yu, S. ; Hu, S. ; Stöger, T. ; Yin, R.
The virulence of NDV NA-1 strain regulated by the 3 ' leader or 5 ' trailer sequences.Gradl, R. ; Morgan, K.S. ; Dierolf, M. ; Jud, C. ; Hehn, L. ; Günther, B. ; Möller, W. ; Kutschke, D. ; Yang, L. ; Stöger, T. ; Pfeiffer, D. ; Gleich, B. ; Achterhold, K. ; Schmid, O. ; Pfeiffer, F.
Dynamic in vivo chest x-ray dark field imaging in mice.