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Kandemir, M. ; Feuchtinger, A. ; Walch, A.K. ; Hamprecht, F.A.
Digital pathology: Multiple instance learning can detect Barrett's cancer.Huber, M. ; Falkenberg, N. ; Schmitt, M. ; Braselmann, H. ; Mall, R. ; Jakovac, M. ; Walch, A.K. ; Höfler, H. ; Aubele, M.
uPAR and its interaction partners: potential new therapy targets in triple negative breast cancer.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Höfig, I. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Bruns, H. ; Buettner, M. ; Fabri, M. ; Mougiakakos, D. ; Bittenbring, J.T. ; Pasemann, S. ; Neumann, F.J. ; Maurberger, A. ; Kempkes, B. ; Mackensen, A. ; Gerbitz, A.
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high grade B-cell lymphoma.Dutta, S. ; Krause, A. ; Vosberg, S. ; Herold, T. ; Ksienzyk, B. ; Quintanilla-Fend, L. ; Tizazu, B. ; Graf, A. ; Krebs, S. ; Blum, H. ; Greif, P.A. ; Schneider, M. ; Dahlhof, M. ; Spiekermann, K. ; Zimber-Strobl, U. ; Wolf, E. ; Bohlander, S.K.
Analysis of the tissue-specific expression requirements and identification of cooperating mutations for leukemogenesis in an inducible CALM/AF10 knock-in mouse model.Jost, P.J. ; Yabal, M. ; Adler, H. ; Knies, N. ; Gross, C. ; Damgaard, R.B. ; Kanegane, H. ; Peschel, C. ; Strasser, A. ; Gross, O. ; Ruland, J. ; Gyrd-Hansen, M.
A mouse model for XLP-2 disease uncovers a critical function for IL-1beta and TNF in driving hyper-inflammation.Jeremias, I. ; Vick, B. ; Rothenberg, M. ; Sandhöfer, N. ; Carlet, M. ; Krupka, C. ; Trumpp, A. ; Corbacioglu, S. ; Ebinger, M. ; Andre, M.C. ; Hiddemann, W. ; Schneider, S. ; Subklewe, M. ; Metzeler, K.H. ; Spiekermann, K.
Bioluminescence in vivo imaging improves the model of individual patients' AML cells growing in mice for sensitive and reliable preclinical treatment trials on various genetic subgroups.Tiedt, S.
Eine seltene und sich langsam teilende Fraktion von Zellen der akuten lymphatischen Leukämie im Knochenmark von NSG-Mäusen ist chemoresistent.Böttinger, N.
Adoptive immunotherapy for treatment of chronic hepatitis B.Becker, L. ; Kling, E. ; Schiller, E. ; Zeh, R. ; Schrewe, A. ; Hölter, S.M. ; Mossbrugger, I. ; Calzada-Wack, J. ; Strecker, V. ; Wittig, I. ; Dumitru, I. ; Wenz, T. ; Bender, A. ; Aichler, M. ; Janik, D. ; Neff, F. ; Walch, A.K. ; Quintanilla-Fend, L. ; Floß, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Meitinger, T. ; Prokisch, H. ; Hrabě de Angelis, M. ; Klopstock, T.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Davari, K. ; Frankenberger, S. ; Schmidt, A. ; Tomi, N.S. ; Jungnickel, B.
Checkpoint kinase 2 is required for efficient immunoglobulin diversification.Ravasz, M.
The role of ORC6 in the human cell.Wachter, F.
Der konträre Einfluss von p53 auf die extrinsische und intrinsische Apoptoseinduktion in Tumorzellen.Sterz, K.
A systematical analysis of the signal transduction pathways induced by the Latent Membrane Protein 1 (LMP1) of Epstein-Barr virus.Maier, S.K.
Towards comprehensive identification of proteins from MALDI imaging.Mannes, A.M.
Dissecting the role of selenothiol- versus thiol-based catalysis using the model enzyme glutathione peroxidase 4 (GPx4).Bruns, H. ; Bittenbring, J.T. ; Mougiakakos, D. ; Fabri, M. ; Buettner, M. ; Pasemann, S. ; Kempkes, B. ; Mackensen, A. ; Gerbitz, A.
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high grade B-cell lymphoma.Yabal, M. ; Müller, N. ; Adler, H. ; Knies, N. ; Gross, C.J. ; Damgaard, R.B. ; Kanegane, H. ; Ringelhan, M. ; Kaufmann, T. ; Heikenwälder, M. ; Strasser, A. ; Gross, O. ; Ruland, J. ; Peschel, C. ; Gyrd-Hansen, M. ; Jost, P.J.
Aberrant TNF signalling in dendritic cells in the absence of XIAP contributes to X-linked lymphoproliferative disease (XLP-2) by exaggerated necroptosis.Baumann, U. ; Fernández-Sáiz, V. ; Rudelius, M. ; Lemeer, S. ; Rad, R. ; Knorn, A.M. ; Slawska, J. ; Engel, K. ; Jeremias, I. ; Li, Z. ; Tomiatti, V. ; Illert, A.L. ; Targosz, B.S. ; Braun, M. ; Perner, S. ; Leitges, M. ; Klapper, W. ; Dreyling, M. ; Miething, C. ; Lenz, G. ; Rosenwald, A. ; Peschel, C. ; Keller, U. ; Kuster, B. ; Bassermann, F.
Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.Friedmann Angeli, J.P.F. ; Schneider, M. ; Proneth, B. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Hammond, V.J. ; Herbach, N. ; Aichler, M. ; Walch, A.K. ; Eggenhofer, E. ; Basavarajappa, D. ; Rådmark, O. ; Kobayashi, S. ; Seibt, T. ; Beck, H. ; Neff, F. ; Esposito, I. ; Wanke, R. ; Förster, H. ; Yefremova, O. ; Heinrichmeyer, M. ; Bornkamm, G.W. ; Geissler, E.K. ; Thomas, S.B. ; Stockwell, B.R. ; O'Donnell, V.B. ; Kagan, V.E. ; Schick, J. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Finkenzeller, C. ; Carlet, M. ; Jeremias, I.
Optimization of lentiviral transduction in patien-derived acute leukemia cells growing mice.Vick, B. ; Rothenberg, M. ; Sandhöfer, N. ; Carlet, M. ; Finkenzeller, C. ; Krupka, C. ; Grunert, M. ; Trumpp, A. ; Corbacioglu, S. ; Ebinger, M. ; Andre, M.C. ; Hiddemann, W. ; Subklewe, M. ; Schneider, S. ; Spiekermann, K. ; Metzeler, K.H. ; Jeremias, I.
Serial transplantation and in vivo monitoring of patient-derived xenografts: An advanced preclinical model to study diverse genetic AML subgroups in mice.Neudoerfl, C. ; Daemen, K. ; Stevanovic-Meyer, M. ; Keil, J.E. ; Hoffmann, U. ; Lehner, F. ; Haller, H. ; Blume, C. ; Hammerschmidt, W. ; Zeidler, R. ; Falk, C.S.
Costimulation blockade by belatacept inhibits allo-specific de novo T cell responses and preserves virus-specific memory T cell responses in healthy donors and kidney transplanted patients.Aichler, M. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Proteomic and metabolic prediction of response to therapy in gastric cancer.Tomi, N.S. ; Davari, K. ; Grotzky, D. ; Loos, F. ; Böttcher, K. ; Frankenberger, S. ; Jungnickel, B.
Analysis of SHPRH functions in DNA repair and immunoglobulin diversification.Huber, K. ; Feuchtinger, A. ; Borgmann, D.M. ; Li, Z. ; Aichler, M. ; Hauck, S.M. ; Zitzelsberger, H. ; Schwaiger, M. ; Keller, U. ; Walch, A.K.
A novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.Gegg, M. ; Böttcher, A. ; Burtscher, I. ; Hasenöder, S. ; van Campenhout, C.A. ; Aichler, M. ; Walch, A.K. ; Grant, S.G. ; Lickert, H.
Flattop regulates basal body docking and positioning in mono- and multiciliated cells.Gabaev, I. ; Elbasani, E. ; Ameres, S. ; Steinbrück, L. ; Stanton, R. ; Döring, M. ; Lenac Rovis, T. ; Kalinke, U. ; Jonjic, S. ; Moosmann, A. ; Messerle, M.
Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-epecific CD8 T cells.Balluff, B. ; Frese, C.K. ; Maier, S.K. ; Schöne, C. ; Kuster, B. ; Schmitt, M. ; Aubele, M. ; Höfler, H. ; Deelder, A.M. ; Heck, A.J. ; Hogendoorn, P.C.W. ; Morreau, J. ; Altelaar, A.F. ; Walch, A.K. ; McDonnell, L.A.
De novo discovery of phenotypic intra-tumor heterogeneity using imaging mass spectrometry.Aichler, M. ; Motschmann, M. ; Jütting, U. ; Luber, B. ; Becker, K. ; Ott, K. ; Lordick, F. ; Langer, R. ; Feith, M. ; Siewert, J.R. ; Walch, A.K.
Epidermal Growth Factor Receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy.Lehnert, C. ; Weiswange, M. ; Jeremias, I. ; Bayer, C. ; Grunert, M. ; Debatin, K.M. ; Strauss, G.P.
TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation.Feuchtinger, A. ; Stiehler, T. ; Jütting, U. ; Marjanovic, G. ; Luber, B. ; Langer, R. ; Walch, A.K.
Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma.Maier, S.K. ; Bashkueva, K. ; Rösli, C. ; Skerra, A. ; Kuster, B.
PAS-cal: A repetitive peptide sequence calibration standard for MALDI mass spectrometry.Mohr, C.F. ; Kalmer, M.A. ; Gross, C. ; Mann, M.C. ; Sterz, K. ; Kieser, A. ; Fleckenstein, B.W. ; Kress, A.K.
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration.Alves, C.C. ; Tiedt, S. ; Jeremias, I.
Identification and isolation of a rare population of low-cycling, self-renewing and drug-resistant acute lymphoblastic leukemia xenograft cells.Bazot, Q. ; Deschamps, T. ; Tafforeau, L. ; Siouda, M. ; Leblanc, P. ; Harth-Hertle, M.L. ; Rabourdin-Combe, C. ; Lotteau, V. ; Kempkes, B. ; Tommasino, M. ; Gruffat, H. ; Manet, E.
Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1.Falk, C.S. ; Daemen, K. ; Stevanovic-Meyer, M. ; Lehner, F. ; Haller, H. ; Blume, C. ; Hammerschmidt, W. ; Zeidler, R. ; Neudoerfl, C.
Belatacept can inhibit allo-specific T cell responses in a donor-dependent manner but preserves virus-specific memory T cell-responses.Slotta-Huspenina, J. ; Becker, K.F. ; Feith, M. ; Walch, A.K. ; Langer, R.
Heat Shock Protein 90 (HSP90) and Her2 in adenocarcinomas of the esophagus.Adler, H. ; Steer, B. ; Juskewitz, E. ; Kammerer, R.
To the editor: Murine gammaherpesvirus 68 (MHV-68) escapes from NK-cell-mediated immune surveillance by a CEACAM1-mediated immune evasion mechanism.Schmitt, S. ; Schulz, S. ; Schropp, E.-M. ; Eberhagen, C. ; Simmons, A. ; Beisker, W. ; Aichler, M. ; Zischka, H.
Why to compare absolute numbers of mitochondria.Buck, A. ; Walch, A.K.
In situ drug and metabolite analyzes in biological and clinical research by MALDI MS imaging.Hojer, C. ; Frankenberger, S. ; Strobl, L.J. ; Feicht, S. ; Djermanovic, K. ; Jagdhuber, F. ; Hömig-Hölzel, C. ; Ferch, U. ; Ruland, J. ; Rajewsky, K. ; Zimber-Strobl, U.
B cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.Graf, N. ; Li, Z. ; Herrmann, K. ; Weh, D. ; Aichler, M. ; Slawska, J. ; Walch, A.K. ; Peschel, C. ; Schwaiger, M. ; Buck, A.K. ; Dechow, T. ; Keller, U.
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma.Bussey, K. ; Reimer, E. ; Todt, H. ; Denker, B. ; Gallo, A. ; Konrad, A. ; Ottinger, M. ; Adler, H. ; Stürzl, M. ; Brune, W. ; Brinkmann, M.M.
The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the toll-like receptor-induced proinflammatory cytokine response.Yabal, M. ; Müller, N. ; Adler, H. ; Knies, N. ; Groß, C.J. ; Damgaard, R.B. ; Kanegane, H. ; Ringelhan, M. ; Kaufmann, T. ; Heikenwälder, M. ; Strasser, A. ; Groß, O. ; Ruland, J. ; Peschel, C. ; Gyrd-Hansen, M. ; Jost, P.J.
XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.Ameres, S. ; Besold, K. ; Plachter, B. ; Moosmann, A.
CD8 T cell-evasive functions of human cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity.Gorzolka, K. ; Walch, A.K.
MALDI mass spectrometry imaging of formalin-fixed paraffin-embedded tissues in clinical research.Huber, K. ; Aichler, M. ; Sun, N. ; Buck, A. ; Li, Z. ; Fernandez, I.E. ; Hauck, S.M. ; Zitzelsberger, H. ; Eickelberg, O. ; Janssen, K.P. ; Keller, U. ; Walch, A.K.
A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.Dekker, T.J. ; Balluff, B.D. ; Jones, E.A. ; Schöne, C.D. ; Schmitt, M. ; Aubele, M. ; Kroep, J.R. ; Smit, V.T. ; Tollenaar, R.A. ; Mesker, W.E. ; Walch, A.K. ; McDonnell, L.A.
Multicenter Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma.Bézière, N. ; von Schacky, C. ; Kosanke, Y. ; Kimm, M. ; Nunes, A. ; Licha, K. ; Aichler, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Meier, R.
Optoacoustic imaging and staging of arthritic inflammation.Weller, P. ; Bankfalvi, A. ; Gu, X. ; Dominas, N. ; Lehnerdt, G.F. ; Zeidler, R. ; Lang, S. ; Brandau, S. ; Dumitru, C.A.
The role of tumour FoxP3 as prognostic marker in different subtypes of head and neck cancer.Kucharska, J. ; del Río, P. ; Arango-González, B. ; Gorza, M. ; Feuchtinger, A. ; Hauck, S.M. ; Ueffing, M.
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.Maetzig, T. ; Kuehle, J. ; Schwarzer, A. ; Turan, S. ; Rothe, M. ; Chaturvedi, A. ; Morgan, M. ; Ha, T.C. ; Heuser, M. ; Hammerschmidt, W. ; Baum, C. ; Schambach, A.
All-in-One inducible lentiviral vector systems based on drug controlled FLP recombinase.Prägert, M.
TALE nucleases as antiviral factors.Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E. ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S. ; Reichert, A.S. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T. ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Frankenberger, S. ; Davari, K. ; Fischer-Burkart, S. ; Böttcher, K. ; Tomi, N.S. ; Zimber-Strobl, U. ; Jungnickel, B.
Checkpoint kinase 1 negatively regulates somatic hypermutation.Sun, N. ; Ly, A. ; Meding, S. ; Witting, M. ; Hauck, S.M. ; Ueffing, M. ; Schmitt-Kopplin, P. ; Aichler, M. ; Walch, A.K.
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry.Gustems, M. ; Woellmer, A. ; Rothbauer, U. ; Eck, S.H. ; Wieland, T. ; Lutter, D. ; Hammerschmidt, W.
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs.Li, Z. ; Herrmann, K. ; Pirsig, S. ; Philipp-Abbrederis, K. ; Henninger, M. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Beer, A.J. ; Ringshausen, I. ; Pomykala, K.L. ; Scheidhauer, K. ; Schwaiger, M. ; Keller, U. ; Buck, A.K.
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma.Wildgruber, M. ; Bielicki, I. ; Aichler, M. ; Kosanke, K. ; Feuchtinger, A. ; Settles, M. ; Onthank, D.C. ; Cesati, R.R. ; Robinson, S.P. ; Huber, A.M. ; Rummeny, E.J. ; Walch, A.K. ; Botnar, R.M.
Assessment of myocardial infarction and post-infarction scar remodeling with an elastin-specific magnetic resonance agent.McDonnell, L.A. ; Walch, A.K. ; Stoeckli, M. ; Corthals, G.L.
MSiMass list: A public database of identifications for protein MALDI MSI.Aichler, M. ; Walch, A.K.
In brief: The (molecular) pathogenesis of Barrett's oesophagus.Vereide, D.T. ; Seto, E. ; Chiu, Y.F. ; Hayes, M. ; Tagawa, T. ; Grundhoff, A. ; Hammerschmidt, W. ; Sugden, B.
Epstein-Barr virus maintains lymphomas via its miRNAs.