Skip to main content
Forschung Toxikologie
Casimiro - stock.adobe.com

Molecular Targets and Therapeutics Center Institute of Molecular Toxicology and Pharmacology

 

At the Institute of Molecular Toxicology and Pharmacology (TOXI), we explore how the human body responds to bioactive chemicals at the molecular level. Our mission is to uncover the complex molecular mechanism, our body’s molecular machines, that determine whether a chemical compound leads to therapeutic benefits or harmful effects.
A central goal of our research is to generate cutting-edge knowledge that drives the development of innovative, effective, and safe pharmaceuticals. Through our work, we contribute to advancing precision medicine and improving drug safety for the future.

 

At the Institute of Molecular Toxicology and Pharmacology (TOXI), we explore how the human body responds to bioactive chemicals at the molecular level. Our mission is to uncover the complex molecular mechanism, our body’s molecular machines, that determine whether a chemical compound leads to therapeutic benefits or harmful effects.
A central goal of our research is to generate cutting-edge knowledge that drives the development of innovative, effective, and safe pharmaceuticals. Through our work, we contribute to advancing precision medicine and improving drug safety for the future.

About our Research

Our research targets the interface between biomedicine and chemistry from complementary perspectives. Specific projects may start from:

elicited by a small chemical in mice or man

pathways

 for novel chemical matter that could address a promising pharmacologic target

screens to unravel the mechanism behind a physiological response to a chemical challenge

Research Groups

Microscopy
Michael Haggenmueller
Göttlicher Group

Small Molecule Modulators of Intermediary Metabolism

Our research aims at identifying novel targets for small molecules that could modulate intermediary metabolism in order to control body weight or pathologies associated with metabolic disorders such as metabolic syndrome, steatosis hepatis or diabetes.

View Group
Mitochondria
microscience - stock.adobe.com
Zischka Group

Mitochondrial Toxicology

We focus on Mitochondrial Damage upon diverse aspects of cell-toxic conditions in human disease, e.g. metabolic diseases, neurodegeneration, cancer, organ failure.

View Group

Our Scientists at Molecular Toxicology and Pharmacology

Porträt Martin Göttlicher_freigestellt

Prof. Martin Göttlicher

Director of the Institute for Molecular Toxicology and Pharmacology / Group Leader Small Molecule Modulators of Intermediary Metabolism View profile

Prof. Dr. rer. nat. Hans Zischka

Group Leader Oxidative Cell Death

Carola Eberhagen

Technical Assistant Zischka Lab

Jonas Engler

Doctoral Researcher Zischka Lab

Tamara Rieder

Technical Assistant Zischka Lab

Quirin Reinold

Technical Assistant Zischka Lab

Adriana Filipa da Silva Fontes

Doctoral Researcher Zischka Lab

Dennis Koob

Doctoral Researcher Zischka Lab

Judith Sailer

Doctoral Researcher Zischka Lab

Dr. Adrian Jauch

Postdoc Zischka Lab

Our Staff in Detail

A lot of people figures and comment clouds above their heads.
0
Employees
0
Postdocs
0
Doctoral Researchers
0
Technicians

Latest Publications of Our Institute

Read more

Contact

Director

Porträt Martin Göttlicher_freigestellt

Prof. Martin Göttlicher

Director of the Institute for Molecular Toxicology and Pharmacology / Group Leader Small Molecule Modulators of Intermediary Metabolism

Building 57, Room 2
View profile