Bioengineering

What happens in encapsulins stays in encapsulins - bioorthogonal compartments in mammalian cells

To sequester multi-component enzymatic processes inside living mammalian cells, we introduce heterologously expressed encapsulins as a versatile platform to generate self-assembling ompartments which can serve as nano-reaction chambers.

We have synthesized a calcium sensor for photoacoustics, which changes its absorbance and thus photoacoustic spectrum upon selective binding to Ca2+ for future use in organoids or in vivo models.

To increase the multiplexing capabilities of gene reporters for multispectral optoacoustic tomography (MSOT), we have introduced the concept of discriminating optoacoustic contrast agents not by color but by time-varying photocontrolled signal…

Bioengineering

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What happens in encapsulins stays in encapsulins | bioorthogonal compartments in mammalian cells

Calcium Sensor for Photoacoustics (CaSPA)

Temporally unmixed MSOT (tuMSOT)

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