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A conceptual image showing a lung-shaped lake in a lush and pristine jungle
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Environmental Health Center

The Environmental Health Center (EHC) is dedicated to combating diseases caused by environmental factors, such as allergies, asthma, and chronic lung diseases, with the primary goal of prevention. Where prevention is not possible, we aim to advance medicine and develop innovative treatments by understanding the underlying mechanisms and translating these into novel drugs.

The Environmental Health Center (EHC) is dedicated to combating diseases caused by environmental factors, such as allergies, asthma, and chronic lung diseases, with the primary goal on prevention. Where prevention is not possible, we aim to advance medicine and develop innovative treatments by understanding the underlying mechanisms and translating these into novel drugs.

Scientists

Selected Publications

See all Publications

2024 Scientific Article in Am. J. Respir. Crit. Care Med.

Jakwerth, C.A. ; Weckmann, M. ; Illi, S. ; Charles, H. ; Zissler, U.M. ; Oelsner, M. ; Guerth, F. ; Omony, J. ; Nemani, S.S.P. ; Grychtol, R. ; Dittrich, A.M. ; Skevaki, C. ; Foth, S. ; Weber, S. ; Alejandre Alcazar, M.A. ; van Koningsbruggen-Rietschel, S. ; Brock, R. ; Blau, S. ; Hansen, G. ; Bahmer, T. ; Rabe, K.F. ; Brinkmann, F. ; Kopp, M.V. ; Chaker, A.M. ; Schaub, B. ; Von Mutius, E. ; Schmidt-Weber, C.B.

17q21 variants disturb mucosal host defense in childhood asthma

2023 Scientific Article in Sci. Transl. Med.

Lang, N.J. ; Schniering, J. ; Porras-Gonzalez, D.L. ; Yang, L. ; De Sadeleer, L.J. ; Jentzsch, R.C. ; Shitov, V.A. ; Zhou, S. ; Ansari, M. ; Agami, A. ; Mayr, C. ; Hooshiar Kashani, B. ; Chen, Y. ; Heumos, L. ; Pestoni, J. ; Molnar, E.S. ; Geeraerts, E. ; Anquetil, V. ; Saniere, L. ; Wögrath, M. ; Gerckens, M. ; Lehmann, M. ; Yildirim, A.Ö. ; Hatz, R.A. ; Kneidinger, N. ; Behr, J. ; Wuyts, W.A. ; Stoleriu, M.-G. ; Luecken, M. ; Theis, F.J. ; Burgstaller, G. ; Schiller, H.

Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis

2022 Scientific article in nature

Kamal, N. ; Tsardakas Renhuldt, N. ; Bentzer, J. ; Gundlach, H. ; Haberer, G. ; Juhász, A. ; Lux, T. ; Bose, U. ; Tye-Din, J.A. ; Lang, D. ; van Gessel, N. ; Reski, R. ; Fu, Y.B. ; Spégel, P. ; Ceplitis, A. ; Himmelbach, A. ; Waters, A.J. ; Bekele, W.A. ; Colgrave, M.L. ; Hansson, M. ; Stein, N. ; Mayer, K.F.X. ; Jellen, E.N. ; Maughan, P.J. ; Tinker, N.A. ; Mascher, M. ; Olsson, O. ; Spannagl, M. ; Sirijovski, N.

The mosaic oat genome gives insights into a uniquely healthy cereal crop

2021 Scientific Article in Science Advances

Gerckens, M. ; Schorpp, K.K. ; Pelizza, F. ; Wögrath, M. ; Reichau, K. ; Ma, H. ; Dworsky, A.-M. ; Sengupta, A. ; Stoleriu, M.-G. ; Heinzelmann, K. ; Merl-Pham, J. ; Irmler, M. ; Alsafadi, H.N. ; Trenkenschuh, E. ; Sarnova, L. ; Jirouskova, M. ; Frieß, W. ; Hauck, S.M. ; Beckers, J. ; Kneidinger, N. ; Behr, J. ; Hilgendorff, A. ; Hadian, K. ; Lindner, M. ; Königshoff, M. ; Eickelberg, O. ; Gregor, M. ; Plettenburg, O. ; Yildirim, A.Ö. ; Burgstaller, G.

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

2020 nature

Conlon, T.M. ; John-Schuster, G. ; Heide, D. ; Pfister, D. ; Lehmann, M. ; Hu, Y. ; Ertüz, Z. ; López, M.A. ; Ansari, M. ; Strunz, M. ; Mayr, C. ; Ciminieri, C. ; Costa, R. ; Kohlhepp, M.S. ; Guillot, A. ; Güneş, G. ; Jeridi, A. ; Funk, M.C. ; Beroshvili, G. ; Prokosch, S. ; Hetzer, J. ; Verleden, S.E. ; Alsafadi, H.N. ; Lindner, M. ; Burgstaller, G. ; Becker, L. ; Irmler, M. ; Dudek, M. ; Janzen, J. ; Goffin, E. ; Gosens, R. ; Knolle, P. ; Pirotte, B. ; Stöger, T. ; Beckers, J. ; Wagner, D.E. ; Singh, I. ; Theis, F.J. ; Hrabě de Angelis, M. ; O’Connor, T. ; Tacke, F. ; Boutros, M. ; Dejardin, E. ; Eickelberg, O. ; Schiller, H. B. ; Königshoff, M. ; Heikenwalder, M. ; Yildirim, A.Ö.

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

Contact

Corinna Barz_freigestellt

Dr. Corinna Barz

Director of Operations (EHC)