Michael Sattler / 2014

Molecular Targets and Therapeutics, STB,

Unlocking the Future of Personalized Medicine

Prof. Michael Sattler on exploring the impact of understanding molecular disease mechanisms and advancing personalized therapies.

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Awards & Grants, ISF, STB,

Three million euros for European research initiative to develop new technology to regenerate the brain

Over the next four years, Helmholtz Munich participates in a European research consortium, aiming to develop an innovative technology that could boost the regeneration of neurons in diseases that currently have limited therapeutic options. The…

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Featured Publication, Molecular Targets and Therapeutics, STB,

New method to investigate the structure and dynamics of challenging membrane proteins

Researchers created a new approach to reduce the complexity of the NMR experiments and facilitate the investigation of membrane protein systems of pharmaceutical importance.

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AI, Featured Publication, STB,

MISATO Dataset: Transforming Drug Discovery with AI

A team led by Helmholtz Munich scientist Dr. Grzegorz Popowicz unveils the Molecular Interactions Structurally Optimized (MISATO) dataset, offering a transformative approach to training AI models for designing new drug molecules. MISATO represents a…

The X-ray of the human brain closeup image

Transfer, Molecular Targets and Therapeutics, STB,

First Patient Administered New Drug for Brain Tumor Treatment

In an ongoing phase 1 clinical trial targeting malignant glioblastoma, the initial patient has received a dosage of a novel drug candidate, derived from an antibody originating at Helmholtz Munich. This innovative compound, coupled with a…

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STB,

Identification of a key factor for splicing long introns

Mutations in FUBP1 cause defective gene regulation in glioma cells

 

Pre-mRNA splicing is an essential step in the maturation of mRNA in which introns are removed and the remaining exons are linked to create a mature mRNA as template for proteins.…