Name of the Institute

Öffentliche Ausschreibung nach VOB/A §3

Eröffnungstermin: 05.10.2023 10:00Uhr

How do our muscles respond at the molecular level to exercise? Researchers at Helmholtz Munich and the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have unraveled the cellular basis and signaling pathways responsible for the positive…

Offenes Verfahren nach VOB/A §3EU

Eröffnungstermin: : 19.10.2023 14:00 Uhr

The two institutions, LHI (Helmholtz-Munich) and Chicago Northestern Medical Center have been meeting monthly online to exchange scientific information to explore cutting-edge advancements in the field of pulmonary and critical care medicine. As a…

How do our muscles respond at the molecular level to exercise? Researchers at Helmholtz Munich and the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have unraveled the cellular basis and signaling pathways responsible for the positive…

An in vitro roadmap guiding vascularization in tissue engineering

With the dilemma of the need for organ transplants by far surpassing available donor organs, the number of patients dying while waiting for a suitable transplant will inevitably…

A collaborative endeavor between computer scientists and diabetes researchers at Helmholtz Munich has yielded novel insights into the mechanisms underlying type 1 and type 2 diabetes. This collaboration has resulted in the creation of the first mouse…

Offenes Verfahren nach VOB/A §3EU

Eröffnungstermin: : 26.09.2023 14:00 Uhr

Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin. While the cause of the autoimmunity reaction is still unclear, viral infections in young children are proposed to be…

Öffentliche Ausschreibung nach VOB/A §3

Eröffnungstermin: 28.09.2023 10:00Uhr

Ensuring the sustainability of oat cultivation as a significant future food source holds great promises for both human health and the climate. Dr. Nadia Kamal, a researcher at the Plant Genome and Systems Biology Group at Helmholtz Munich, has been…

Premature infants often struggle with breathing and require ventilatory support and oxygen therapy. Unfortunately, this might lead to lung damage resulting in lifelong consequences and chronic disease. Dr. Anne Hilgendorff’s team from Helmholtz…

A recent discovery led by Dr. Anika Seel and Dr. Kurt Schmoller at the Institute for Functional Epigenetics (IFE) at Helmholtz Munich has uncovered a fascinating link between cell size and mitochondrial DNA regulation, shedding light on a previously…

In collaboration with Helmholtz Munich, Medigene is expanding its portfolio of costimulatory switch proteins in the field of cancer immunotherapy. By expanding the license field, these specialized proteins, initially developed by Helmholtz Munich,…

ERS Early Career Member Award for her work on cellular senescence in chronic lung diseases like COPD and IPF

Ensuring the sustainability of oat cultivation as a significant future food source holds great promises for both human health and the climate. Dr. Nadia Kamal, a researcher at the Plant Genome and Systems Biology Group at Helmholtz Munich, has been…

Researchers from Helmholtz Munich have reached a significant milestone in precision medicine with their new publication on the 'Oncology Biomarker Discovery (OncoBird)' framework. This innovative approach aims to systematically identify actionable…

With a 2.25 million US dollar grant provided by the Juvenile Diabetes Research Foundation (JDRF), Prof. Matthias Hebrok, Prof. Heiko Lickert, and Prof. Carolin Daniel from the Helmholtz Munich Diabetes Center, and Prof. Eckhard Wolf from Ludwig…

Helmholtz Munich researchers receive 2.25 Mio US Dollar JDRF Grant 

With a 2.25 million US dollar grant provided by the Juvenile Diabetes Research Foundation (JDRF), Prof. Matthias Hebrok, Prof. Heiko Lickert, and Prof. Carolin Daniel from the…

Clarifying a debated issue in clinical practice:

Thousands of patients are injected with contrast media every day, particularly in the fields of radiology and internal medicine. It has long been debated whether, and if so to what extent, there is a…

Colorectal cancer (CRC) ranks second in leading causes of cancer-related deaths globally, according to the WHO. For the first time, researchers from Helmholtz Munich and the University of Technology Dresden (TU Dresden) show that artificial…

Helmholtz Munich and the Eric and Wendy Schmidt Center at the Broad Institute launch Collaborative Research Initiative

Helmholtz Munich and the Eric and Wendy Schmidt Center at the Broad Institute of MIT and Harvard announced the launch of a…

A team of researchers from Helmholtz Munich in cooperation with scientists at the University Hospital Münster (UKM) has uncovered a new pathway that promotes the growth of aggressive blood cancer, so-called lymphomas. Survival of many lymphomas…

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Clarifying a debated issue in clinical practice 

Thousands of patients are injected with contrast media every day, particularly in the fields of radiology and internal medicine. It has long been debated whether, and if so to what extent, there is a…

The workshop of the Molecular Targets and Therapeutics centre on July 7th was a great success with over 200 external and internal participants.

KI Serie "Wahnsinn und Methode" der Süddeutschen Zeitung, 23. August 2023

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Offenes Verfahren nach VOB/A §3EU

Eröffnungstermin: : 25.09.2023 14:00 Uhr

An interview with Prof. Ulrike Protzer

An interview with Prof. Ulrike Protzer

DNA origami structures fitted with antibodies help immune system to target cancer cells

Immunotherapy is viewed as an exceptionally promising weapon in the fight against cancer. In essence, the aim is to activate the body’s immune system in such a…

An interview with Prof. Reinhard Zeidler

An interview with Prof. Reinhard Zeidler

Helmholtz Munich CEO and passionate physician and scientist Prof. Matthias Tschöp is awarded for his groundbreaking work in metabolic research with this year's Ernst Schering Prize. The jury of the Schering Stiftung honors his discovery of the hunger…

Dr. Na Cai, Principal Investigator at the Helmholtz Pioneer Campus and at the Computational Health Center at Helmholtz Munich, has been honored with this year's Friedmund Neumann Prize awarded by the Schering Foundation. The prize recognizes…

Johannes Wenner Research Prize for Dr. Nicole Maison (IAP, Helmholtz Munich)

Alzheimer's, stroke, multiple sclerosis and other neurological diseases cause severe damage due to neuroinflammation mediated by immune cells. Managing this inflammation poses a significant medical challenge because the brain is protected by the…

The Life Science Factory incubator initiated by Sartorius in Göttingen and the top biomedical research center Helmholtz Munich are entering into a strategic partnership to support spin-offs in the life sciences. Within this framework, the Life…

We pay tribute to the loss of a remarkable scientist, Colyn Crane-Robinson, who passed away on 5th March 2023. Throughout his lifetime, Colyn's unwavering dedication and infectious enthusiasm enriched our understanding of nucleic acid structures and…

Lung research at Helmholtz Munich has made some spectacular breakthroughs. They could pave the way for the therapy of serious diseases.

In July, the Torres-Padilla lab published two new manuscripts showcasing their latest research contributions.

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Dez 23 Chromium Next GEM Single, Chromium Next GEM Chip J 10x Genomics, Inc.

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Verhandlungsverfahren ohne TW

Helmholtz Munich has been honored with the prestigious Total E-Quality award for the seventh time, covering the years 2023 to 2025. The research center has consistently demonstrated its commitment to promoting equal opportunities and diversity and…

Prof. von Mutius is one of nine exceptional individuals who have been awarded the "Bavarian Nobel Prize" this year for their outstanding work in the fields of science and art.

Prof. Michael Schloter, a microbiologist known for his expertise in microbiome research, has been appointed to a professorship of Environmental Microbiology at the Technical University of Munich (TUM). With an impressive academic background and a…

Prof. Dr. Antje Körner started as head of the Metabolism Division at the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) on July 1, 2023.

The foundations for resistant varieties are being developed through genome-assisted breeding and decoding of the complex hop genome as part of the new research project PANHOP at Helmholtz Munich. These varieties should counteract the effects of…

Join us at the Munich Epigenetics Spotlight Meeting 16.10.23!

We will have talks selected from the abstracts, flash talks and 2 invited speakers - secure you spot now!

Dr. Michael Zech received the David Marsden Award 2023 from Dystonia Europe at the 9th EAN Congress in Budapest, Hungary. The award recognizes his groundbreaking research on the genetics of movement disorders, particularly dystonia.

"My vision is to combat COPD so effectively that it ranks only 20th among causes of death!” says the director of the Helmholtz Munich Institute of Lung Health and Immunity (LHI)

"M1 - Munich Medicine Alliance" established as a strategic alliance for excellence in healthcare in Munich.

The IUBMB Focused Meeting on Integrative Omics of Nuclear Functions co-organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place in Crete (Greece) on October 15-20, 2023.

The newly established professorship of Experimental Pneumology, effective from July 1, 2023, focuses on investigating the immunological foundations of respiratory diseases.

The Helmholtz Pioneer Campus was officially inaugurated today under the slogan "ENGINEERING THE FUTURE OF MEDICINE". Commissioning this new state-of-the-art research facility is a significant milestone for young talents in medical research and…

Why “Eating Your Greens” Represents a Major Aspect of Lifestyle Driven Obesity Treatment.

Researchers headed by Dr. Maria Keller (HI-MAG) and Prof. Iris Shai (Ben-Gurion University) investigated the underlying epigenetic effects of a so-called…

Why “Eating Your Greens” Represents a Major Aspect of Lifestyle Driven Obesity Treatment

Researchers developed a new method called wildDISCO that uses standard antibodies to map the entire body of an animal using fluorescent markers. This revolutionary technique provides detailed 3D maps of structures, shedding new light on complex…

The coexistence of multiple chronic diseases in a single individual, defined as multimorbidity, poses a significant challenge in healthcare as the global population ages. In a collaborative effort, researchers investigated the link between type 2…

Outstanding scientists from all over the world come together at Helmholtz Munich's Pioneer Campus. They bring technologies and ideas that are ground-breaking - and thus open up entirely new perspectives for medical research.

In a cross-departmental collaboration with the Institute for Diabetes and Cancer (IDC) and the Institute of Virology (Viro), researchers from the Schneider lab (Institute of Functional Epigenetics, IFE) have discovered a novel axis connecting…

The increase in heat periods as a result of climate change can be more critical for people with diabetes than for metabolically healthy people. This is especially true at older ages. The article "Heat and diabetes" from diabinfo.de deals with helpful…

A research team at Helmholtz Munich revealed a specific mechanism that is able to promote cell death in cancer cells by pharmacological targeting of a ferroptosis surveillance system. Ferroptosis is a form of regulated oxidative cell death and has…

Prof. Fabian Theis, the AI expert, Director of the Computational Health Center at Helmholtz Munich, and Coordinator of Helmholtz AI takes on another important role for AI-based medical research: As Director for Biomedical AI, he complements the…

Over the past decades, epidemiological studies have clearly demonstrated the effects of air pollution on health. There are now explicit recommendations from the World Health Organization regarding guidelines for particulate matter, especially PM2.5…

Diagnosis of type 1 diabetes (T1D) can come with serious complications for families: too often, the autoimmune disease is only detected after severe symptoms develop. In Germany, more than 20 percent of all children and adolescents diagnosed with T1D…

A team of researchers led by Dr. Marcus Conrad from Helmholtz Munich discovered a novel anti-cancer drug, called icFSP1, which sensitizes cancer cells to ferroptosis. Ferroptosis is characterized by the iron-dependent oxidative destruction of…

LHI Scientist Lin Yang Awarded with 1st Prize

The International Society for Computational Biology (ISCB) annually recognizes exceptional individuals in the fields of computational biology and bioinformatics through its prestigious Fellows program. This year, Prof. Fabian Theis, Head of the…

Am vergangenen Freitag, 23.06.2023, fand die Lange Nacht der Wissenschaften in Leipzig erstmals nach 5 Jahren wieder live vor Ort(en) statt und das HI-MAG war dieses Mal dabei. In unseren Räumlichkeiten in der Philipp-Rosenthal-Str. 27 haben wir die…

For major breakthroughs, the American Diabetes Association (ADA) awards its highest honor, the Banting Medal for Scientific Achievement named after the nobel laureate and discoverer of insulin, Frederick Banting. Helmholtz Munich CEO and Humboldt…

Prof. Matthias Tschöp explains why multi-receptor drugs are game changers in treating obesity and preventing diabetes effectively and safely – and why they are not a “miracle treatment” for a dream body. This year, he received the Banting Medal for…

The cooperation between DDN and Helmholtz Munich has been recognized for its work in accelerating AI-driven discoveries that deliver concrete benefits to society and human health.

On 14 June 2023, the members of the WBGU have handed over the new flagship report to the Federal Minister for the Environment, Steffi Lemke, and to State Secretary Judith Pirscher, Ministry of Education and Research, at a federal press conference in…

Human health is closely connected to the health of our environment. So far, the complex ways in which they influence each other are not fully understood. The concept of One Health recognizes this interconnectedness of human, animal, and environmental…

In January 2023, Helmholtz Imaging called for the Best Scientific Image for the third consecutive time. The winners were announced during the award ceremony on June 15, 2023, at the 3rd Annual Helmholtz Imaging Conference 2023. Lin Yang from the…

Mithilfe von Künstlicher Intelligenz lässt sich unter anderem die frühe Diagnose von Krankheiten verbessern und die roboterassistierte Chirurgie gewinnt an Aufwind. Ein Gespräch mit Julia Schnabel und Michael Ghadimi über gegenwärtige Möglichkeiten…

HI-MAG held a symposium to celebrate its 5th anniversary. A large number of guests participated in the event to collectively celebrate previous achievements in the field of health research related to obesity, metabolic, and vascular diseases.

Investigating Metabolic, Obesity and Vascular Diseases

The Helmholtz Institute for Metabolic, Obesity and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG), an institute from Helmholtz Munich at the…

The analysis of single-cell RNA-sequencing data is a powerful tool for identifying new types of cells. However, the rarer the cells are, the more challenging it becomes to find and characterize them. This means that rare cells can often go unnoticed,…

Can a human organ be mapped on a single-cell level to learn about the functionality of each individual cell? And can we learn how different these cells are from person to person? Helmholtz Munich researchers and their collaborators have taken up this…

Cells use editing tools to skip or rearrange information stored in DNA. Thanks to a 10-million-euro ERC Synergy Grant co-financed by ERC and UKRI, researchers have launched a new project to study how this machinery can be controlled with molecular…

Breathtaking presentations of LHI/CPC scientists at Pint of Science Munich

Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes. Although the drug is designed to activate receptors…

CAMPA, a new deep-learning framework, that allows for analysis of subcellular organization in healthy and perturbed cells using high-resolution fluorescence microscopy data has now been introduced in Nature Methods. This tool can facilitate the…

New algorithm six times more reliable at predicting defective RNA

So far, it has not been possible to explain the causes of around half of all rare hereditary diseases. A Munich research team has developed an algorithm that predicts the effects of…

Predicting the effects of drugs regarding dosage, timing, possible drug combinations and other types of intervention such as gene knockouts can be experimentally difficult and very time-consuming. Nonetheless, this is one of the most important tasks…

Enabling Breakthroughs in High-Resolution Structural Analysis of Therapeutic Targets and their Visualization in the Native Cellular Context

The Leopoldina as German National Academy of Sciences provides science-based advice to policymakers and the public, promoting a scientifically enlightened society and responsible application of scientific insights. Prof Maria-Elena Torres-Padilla…

Inflammatory fatty liver disease (NASH, nonalcoholic steatohepatitis) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ), Helmholtz Munich and the Technical University Munich…

During the COVID-19 pandemic, an increase in the chronic autoimmune disease type 1 diabetes was observed in children, also in Germany. Researchers at Helmholtz Munich and TU Dresden, in cooperation with the Kassenärztliche Vereinigung Bayern (KVB),…

The German Diabetes Society (DDG) awards this year's Werner Creutzfeldt Prize to Helmholtz Munich scientist PD Dr Timo Müller for his exceptional work in the research field of Incretin-based diabetes and obesity. This is already the second time in a…

A new study conducted by Helmholtz Munich researchers reveals that ultrafine particles, representing the smallest size fraction of particulate air pollution, might be more dangerous to human health than larger particles. These findings add to the…

A new ad hoc working group with the topic of “artificial intelligence in medicine” started at the Bavarian Academy of Sciences and Humanities (BAdW). The project is planned for three years and will be executed by the Bavarian Academy of Sciences and…

Prof. Reinhard Zeidler about hope in the fight against glioblastoma, the most common and malignant form of brain tumor and how he accelerates the development of antibodies into application.

It is commonly known that DNA assembles into heterochromatin, a densely composed structure, thereby preventing access to the information encoded by the DNA and gene expression. Until now it is not completely understood how this structure forms during…

Triose phosphates (TPs) are the primary products of photosynthetic CO₂ fixation in chloroplasts, which need to be exported into the cytosol across the chloroplast inner envelope (IE) and outer envelope (OE) membranes to sustain plant growth.

A team…

Lean, metabolically unhealthy, people have a risk of cardiovascular disease (CVD) that is higher than the risk observed in obese, metabolically healthy people. Recently, novel cluster analyses (computer-based grouping of people) also identified a…

Lean, metabolically unhealthy, people have a risk of cardiovascular disease that is higher than the risk observed in obese, metabolically healthy people. Recently, novel cluster analyses also identified a large heterogeneity in the risk of type 2…

Helmholtz Munich and Medigene AG expand their partnership in order to further discover and develop T-cell immunotherapies for solid tumors. Medigene acquired from Helmholtz Munich the exclusive, worldwide rights to the CD40L-CD28 Costimulatory Switch…

The two-year High Potentials Program at Helmholtz Munich starts with 13 selected postdocs in its first round in April 2023, supporting the fellows in their career development. The passionate fellows have different scientific expertise coming from…

Please see these new gene reporters for Electron Microscopy

Most children displayed SARS-CoV2 immunity. In March 2023, SARS-CoV2 antibodies were present in 94% of the children, including infants.

Genetically encoded nano-barcodes

How do the nerve cells in our brain communicate with each other? What processes take place when T cells render cancer cells harmless? Details of the mechanisms at the cellular level remain hidden from view. Now,…

The national diabetes information portal diabinfo.de provided by Helmholtz Munich, the German Diabetes Center (DDZ) and the German Center for Diabetes Research (DZD) now offers a large number of its services in the areas of "Preventing Diabetes" and…

The biologist and medical researcher Matthias Hebrok was awarded the Bavarian Distinguished Professorship. Since 2022 Prof. Hebrok is Director at the Institute for Diabetes and Organoid Technology (IDOT)) at Helmholtz Munich. The Bavarian Ministry of…

From 2023 to 2027, nanoPASS will unite research labs, technology and industrial companies to achieve an ambitious goal: to close the knowledge gaps in nanosafety testing.

A specific molecule excreted by methane-oxidizing bacteria could be most suitable for therapy against Wilson’s disease (WD). This is what researchers led by Helmholtz Munich scientist Hans Zischka have found in a new study. In a WD rat model, the…

From 2023 to 2027, nanoPASS will unite research labs, technology and industrial companies to achieve an ambitious goal: to close the knowledge gaps in nanosafety testing. Within the consortium, LHI PIs Tobias Stöger and Markus Rehberg (Helmholtz…

Predicting the therapeutic effects of newly discovered drug candidates in the human body is one of the biggest challenges in early drug development. Scientists need to replicate the complexity of human organs and tissues in models, that are suitable…

Three young scientists of the IDM can count themselves among the winners of last years DZD Award. The award ceremony took place during the 26th DZD Workshop hosted in Tübingen.

Das Bild wird über die AC-Einbettung unscharf und abgeschnitten eingebunden

From now on, an improved research infrastructure for pandemic management and prevention will be available in the Greater Munich area: on the 29th of March 2023 a new biosafety level 3 laboratory was introduced at Helmholtz Munich. The project could…

During the Corona pandemic, experts from Helmholtz Munich helped to bring the situation under control as quickly as possible. Now they are preparing for the possibility of another pandemic: with new high-tech equipment and closely interlinked…

Daniel Krappmann about his new Research Unit "Signaling and Translation" at Helmholtz Munich

The EU-funded ISLET project brings together leading experts in the field of stem cell research to discover a new advanced cell therapy in type 1 diabetes. The aim is to free patients from the daily use of an insulin pump by replacing the damaged…

Analysis of genes can help in detecting diseases at an early stage as well as in determining new drug targets for therapy. Thanks to extremely powerful data processing, the field holds great promise for advancement. Helmholtz Munich is particularly…

The German Research Foundation (DFG, Deutsche Forschungsgemeinschaft) awarded Fabian Theis the Gottfried Wilhelm Leibniz Prize – the most prestigious research award in Germany. Fabian Theis is Head of the Computational Health Center at Helmholtz…

Munich scientists from the fields of proteomics, informatics, and medicine are working together on a large-scale project to investigate the causes of diseases of the central nervous system, how they can be diagnosed, and how treatment can be…

Loitering lung cells and cell death in COPD, female researchers with hijab, and the podcast host's concern after 20 years of cigarette use: the new episode of "Resonator" is an extraordinary conversation about Aicha Jeridi's research at the Institute…

Interdisciplinary cooperation between LMU and Helmholtz Munich supported by Bavarian Research Foundation

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that…

Clinical trials are a milestone in the development of safe and effective drugs and therapies. An antibody developed by Helmholtz Munich is now entering a phase 1 clinical trial. Together with the radiopharmaceutical company ITM Isotope Technologies…

ISEE2026 is coming to Munich!

In the future, blood samples from patients can be evaluated not only by specialists, but also by artificial intelligence. A team from Helmholtz Munich is laying the foundations for this.

Numerous renowned female researchers work at Helmholtz Munich. Ensuring that female scientists receive the best support for their careers is an important element in promoting excellence.

Sex differences exist in the regulation of energy homeostasis, the organism’s mechanism to keep a stable body weight. Current studies indicate for instance that female mammals, including humans, are better protected against metabolic diseases during…

The Paris-Munich Epigenetics Workshop & Symposium organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place at the Max Planck Institute of Biochemistry in Munich on June 14-16, 2023.

Amyotrophic Lateral Sclerosis (ALS) is a non-curable degenerative disease of the motor nervous system. The cause of the disease is largely unknown: In addition to genetic factors, viruses are also suspected to be involved in the development of the…

COPD or pulmonary fibrosis - many chronic lung diseases develop in old age or worsen drastically in the later years of life. Which processes, which molecular processes play a role here? Prof. Dr. Mareike Lehmann, since 2020 group leader at the…

With this new campaign, scientists want to raise awareness for early detection and prevention of type 1 diabetes in children.

Artificial intelligence is increasingly shaping our daily lives. From digital assistants on cell phones to complex systems in mobility or industrial production - it is impossible to imagine life without this key technology.

LHI/CPC group leader Theodoros Kapellos will have a great opportunity for international scientific exchange this year 2023. He applied for a short-term research fellowship at the European Respiratory Society (ERS) and was accepted.

Identification of a previously unknown function of adipose tissue in insulin secretion.

Scientists at Helmholtz Munich and the University of Augsburg have made an important breakthrough in better understanding early processes in the development of…

Type 2 diabetes disease progression and successful intervention depend on individual’s unique clinical, genetic, genomic, and environmental information partly represented by gene expression patterns. An international team of researchers around…

The Bavarian State Government appoints Helmholtz Munich researcher Claudia Traidl-Hoffmann as special representative for climate resilience and prevention. The Bavarian Minister of Health, Klaus Holetschek, will present the special representative and…

The campaign “Women@HelmholtzMunich” aims to increase the visibility of women in science and to empower and support women at Helmholtz Munich in their work. With a series of events and social media presence, the campaign will be running between the…

Helmholtz Munich researcher Dr Vincent Fortuin is one of the young investigator group leaders at Helmholtz AI. His work focuses on the interface between Bayesian inference and deep learning. Bayesian inference is a statistical method to learn from…

Non-alcoholic fatty liver disease (NAFLD) is an important risk factor for type 2 diabetes and cardiovascular diseases. In a Perspective in Cell Metabolism, Norbert Stefan from Helmholtz Munich, the German Center for Diabetes Research and the…

Modern cancer therapy aims to tailor treatment to each individual patient's needs by identifying specific molecular targets with essential functions in the tumor of these patients. Leukemia, or blood cancer, is a common tumor in children and occurs…

Before a cell divides, the genomic content of a cell is duplicated during DNA replication. Each cell has many origins of replication (ORIs), but not all are active at the same time, and some fire earlier and some later. Combining their approach to…

Matthias Hebrok about his new Institute for Diabetes and Organoid Technology (IDOT) at Helmholtz Munich

Am Freitag, dem 03.02.2023, konnte das HI-MAG sich und seine Arbeit auf der SPIN2030 in der Kongresshalle des Leipziger Zoos mit einem eigenen Messestand in Kooperation mit der Universität Leipzig vorstellen.

How can the clinical translation of research findings be accelerated to improve human health? What role does bioengineering play in driving the development of medicine and biology solutions? Matthias Tschöp, CEO at Helmholtz Munich and Alexander von…

On January 1, 2023, Prof. Jürgen Behr and Gerolf Schmidl received active support from the field of lung research on the Foundation's Board of Directors of Stiftung Atemweg. Dr. Ali Önder Yildirim, Director of the Instititute of Lung Health and…

The pandemic, war, or climate change are stressful for many people. In response to stress, the body’s own hormones glucocorticoids are released. High stress hormone levels are associated with metabolic disease and aging, whereas dieting might…

Mohammad Lotfollahi wins the prestigious Bayer Foundation "Early Excellence in Science Award" in the category "Data Sciences" in Life Sciences for his pioneering machine learning algorithms.

Every year, the Bayer Foundation awards the Early Excellence in Science Award. This year’s winner in the category “Data Science in the Life Sciences” is Helmholtz Munich researcher Mohammad Lotfollahi from the Institute of Computational Biology. With…

How do I stay healthy? What impact do my environment and lifestyle have on my health? And how can I prevent, treat, or even cure chronic diseases like diabetes, allergies, or lung diseases?

Helmholtz Munich researcher Carsten Marr, Director of the Institute of AI for Health, has acquired a European Research Council (ERC) Proof of Concept Grant for his project on the development of LeukoScreen, an AI-based software to automatically…

The Gordon Research Conference "Chromatin Modifications in Health and Disease", co-organised by Robert Schneider, will take place from June 11-16,2023, at Bryant University in Rhode Island. The deadline for abstract submission is on May 14, 2023.

The lab of the Institute of Environmental Health at Helmholtz Munich and the Chair of Environmental Medicine at the University of Augsburg has been awarded a certificate of sustainability.

The SARS-CoV-2 pandemic has challenged public health worldwide. The European project ORCHESTRA - Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic - was launched in December 2020 to unite European knowledge…

Blood Bots

By leveraging the power of AI, computers can detect leukemia in blood samples – with accuracy to match their human counterparts

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ergo in gubernando nihil, in officio plurimum interest, quo in genere peccetur. Etiam beatissimum? Duo Reges: constructio interrete. Quod vestri quidem vel optime disputant, nihil opus esse…

The German Research Foundation funds a new Collaborative Research Centre (CRC)/Transregio (TRR) which aims at employing regulatory T cells to create the basis for tailor-made immunotherapies. This initiative is an alliance of the University Mainz and…

Prof. Dr. med. Dr. h.c. Matthias H. Tschöp has been the Helmholtz Vice President of Health Research since January 2023. His goal is to accelerate the development of new solutions for the health challenges of our time.

muzsmudmudd jrsjzt djz sjs jzrs

Helmholtz Munich scientist Lara Urban has been selected by academics as the Young Scientist of the Year 2022. The academics Young Scientist Award, which is endowed with 5,000 €, honors young scientists who have made lasting advances in their…

Helmholtz AI is a research-driven hub for applied artificial intelligence (AI) and one of five platforms initiated by the Helmholtz Information and Data Science Incubator. Three years after the foundation, Helmholtz AI underwent a review in October…

Matthias Tschöp, CEO of Helmholtz Munich, talks about translating scientific discoveries into clinical practice, about ambitious targets, and about ideas he acquired during his time in the USA.

The development of laboratory capacities within the framework of the EU-funded project for pandemic management and prevention "PerForM-REACT" continues to progress at the Augsburg site

In a highly competitive procedure, the Group Metabolic Imaging at the IDM was approved by the DFG for 3 years of funding.

The renal phosphate wasting disease X-linked hypophosphatemia (XLH) is a rare metabolic disorder of the bones associated with severe renal phosphate loss. The first symptoms of the genetic defect appear in childhood and adolescence and can…

Week after week, Sven Oswald and Daniel Finger dedicate themselves to a new topic. A medal may have ONE flip side, a topic has COUNTLESS facets. Two on ONE tries to illuminate them. In this episode, Prof. Dr. Andreas Birkenfeld talks about a new…

Congratulations!

Claudia Traidl-Hoffmann was newly appointed to the German Advisory Council on Global Change by the German Federal Cabinet on December 21, 2022.

www.helmholtz-munich.de/en/sat

Researchers from the Institute for Epigenetics and Stem Cells at Helmholtz Munich studied RNA Polymerase II (Pol II) in early mouse embryos and shed light on transcriptional elongation during zygotic genome activation (ZGA), a key process of…

Researchers from the Institute for Epigenetics and Stem Cells at Helmholtz Munich studied RNA Polymerase II (Pol II) in early mouse embryos and shed light on transcriptional elongation during zygotic genome activation (ZGA), a key process of…

Review of the presentation by Claudia Traidl-Hoffmann, Head of the 'Institute of Environmental Medicine', IEM (Helmholtz Munich/Environmental Health Center) at the 2022 United Nations Climate Change Conference.

Hepatitis B virus (HBV) infections remain a major global health problem – according to the World Health Organization (WHO) there are around 300 million HBV carriers worldwide. Current treatments rarely succeed in curing the infection. At present,…

How can you trace a single diseased cell in an intact brain or a human heart? The search resembles looking for a needle in a haystack. The teams of Ali Ertürk at Helmholtz Munich and LMU Munich and Matthias Mann at the Max Planck Institute of…

Which factors drive non-communicable inflammatory skin diseases? A research team led by Stefanie Eyerich, Michael Menden, as well as Kilian Eyerich have investigated this question and applied a new spatial transcriptomics technology, that gives…

Medical gaps in the treatment of incurable pulmonary fibrosis: LHI/CPC group leader Prof. Mareike Lehmann explains in the Süddeutsche Zeitung report how lung cells age and sometimes behave like zombies.

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene. The result is…

Claudia Traidl-Hoffmann was newly appointed to the German Advisory Council on Global Change (WBGU) by the German Federal Cabinet on December 21, 2022. Since the summer of 2022, she has also been a member of the „Environmental Public Health”…

A research team from Helmholtz Munich and the Leipzig University’s Faculty of Medicine has discovered a new mechanism that is associated with severe obesity in children. This genetic rearrangement leads to an unusual expression of a gene that can…

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

Klaus Mayer (Director Research Unit Plant Genome and Systems Biology, PGSB) and Michael Schloter (Director Research Unit for Comparative Microbiome Analysis, COMI) are among the 7,000 scientists most cited in 2022. That's according the new list from…

In the perspective article "In preprints: improving and interrogating embryo models", Antonio Scialdone from the Institute for Epigenetics and Stem Cells, the Institute of Functional Epigenetics, and the Institute of Computational Biology at…

In the perspective article "In preprints: improving and interrogating embryo models", Antonio Scialdone from the Institute for Epigenetics and Stem Cells, the Institute of Functional Epigenetics, and the Institute of Computational Biology at…

You are excited about understanding life? You would like to gain hands-on research experience and find out more about the daily life of scientists?

The call for our SUMMER INTERNSHIP PROGRAM 2023 IN EPIGENETICS, STEM CELLS, AND ARTIFICAL…

It is well known that genes and environmental factors such as air pollutants, bacteria and also diet can influence the development of allergies or asthma. Researchers at Helmholtz Munich have now examined the role of food in more detail. Their…

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

The Paul G. Allen Frontiers Group, a division of the Allen Institute, announced today the names of the 16 new Allen Distinguished Investigators for 2022. Bilal Sheikh from the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)…

Der tagesschau Zukunfts-Podcast: mal angenommen · 15.12.2022 · 27 Min.

The medical technology company Dermagnostix GmbH is a joint spin-off of Helmholtz Munich, the Technical University (TU) Munich and Hahn-Schickard. Its goal: to redefine molecular diagnostics in dermatology. Dermagnostix has now qualified as one of 30…

How is a muscle protein related to energy production in brown adipose tissue (BAT)? And could this be a possible starting point in the fight against obesity? A team of researchers led by John Heiker from the Helmholtz Institute for Metabolic, Obesity…

The Review Board for Medicine of the Deutsche Forschungsgemeinschaft (DFG) has appointed Helmholtz Munich scientist Dr. Marcus Conrad as a new member of the DFG’s Hinterzarten Circle on Cancer Research. Marcus Conrad succeeds Prof. Greten from…

How is a muscle protein related to energy production in brown adipose tissue (BAT)? And could this be a possible starting point in the fight against obesity? A team of researchers led by John Heiker from the Helmholtz Institute for Metabolic, Obesity…

The discovery of gut hormone dual and triple co-agonist drug classes by Matthias Tschöp and Richard DiMarchi has led to a series of new therapeutics in clinical development. The first co-agonist at the receptors for GLP-1 and GIP has recently been…

The cooperation of LMU, Helmholtz Munich, Bundeswehr University and TUM, receives funding for another period of four and a half years.

Helmholtz Munich researcher Boyan Bonev, Principal Investigator of the research group “3D Genome and Molecular Neurobiology” at the Helmholtz Pioneer Campus, is selected as a new EMBO Young Investigator. Today, the European Molecular Biology…

In his testament, a deceased member of the Deutscher Diabetiker Bund (DDB) e. V. stated the will to support diabetes research with 200 000 Euro. The money was now donated to the Institute of Diabetes Research of Helmholtz Munich (IDF) led by…

Through the course of the last several decades, the rate of obesity has progressively increased and is now one of the leading causes of death worldwide – according to the World Health Organization (WHO) 650 million adults are classified as obese. The…

Through the course of the last several decades, the rate of obesity has progressively increased and is now one of the leading causes of death worldwide – according to the World Health Organization (WHO) 650 million adults are classified as obese. The…

Data Science can help save lives. Julia Schnabel talked about the potential of machine learning solutions for medical imaging applications, such as early detection of diseases.

When a cell divides, the correct distribution of cellular content, such as RNAs, to daughter cells is essential. By tagging RNAs with the new diSpinach aptamer in combination with a self-made microfluidics device, researchers at the Institute of…

We introduce a new gene reporter system (INSPECT) that encode reporter or effector proteins from intronic information.

New biological tool for tracking cellular processes

Cells must continuously adjust to their environments and cope with changing temperatures, stress conditions, or resources. Particularly, if conditions change repeatedly, it might make sense for cells to adjust more effectively. A collaborative…

Cells must continuously adjust to their environments and cope with changing temperatures, stress conditions, or resources. Particularly, if conditions change repeatedly, it might make sense for cells to adjust more effectively. A collaborative…

Anlässlich des Weltdiabetestages am 14. November wurden Kathrin Landgraf und Robert Stein, die beide in der Arbeitsgruppe von Antje Körner im Pädiatrischen Forschungszentrum der Universitätsmedizin Leipzig tätig und Gastwissenschaftlerin bzw.…

The researchers Adam C. O’Neill, Fatma Uzbas, Giulia Antognolli and Florencia Merino as well as Magdalena Götz at Helmholtz Munich and Ludwig-Maximilians-University Munich (LMU) receive the “GSCN 2022 Publication of the Year Award” for their joint…

Does exercise help against diabetes and obesity? Researchers around PD Dr Stephanie Kullmann from Helmholtz Munich and DZD have investigated this question in a clinical study. The results show that just eight weeks of exercise can help restore the…

The fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.

The fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.

The fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.

„Everyone’s health is at the mercy of fossil fuels” is the central finding of this year’s Lancet Countdown on Health and Climate Change report. In this report, which was released on October 26th 2022, experts warn of health consequences of the…

„Everyone’s health is at the mercy of fossil fuels” is the central finding of this year’s Lancet Countdown on Health and Climate Change report. In this report, which was released on October 26^th 2022, experts warn of health consequences of the…

Inspired by recent work from Antonio Scialdone’s group on the spatial expression of olfactory neurons, Maria Elena Torres Padilla and Robert Schneider, directors of IES and IFE respectively, teamed up with the Deutsches Museum to share our research…

How do single cells communicate in a tissue? How can these interactions be modeled, while retaining information of spatial context? Researchers around Fabian Theis from Helmholtz Munich Computational Health Center and Technical University of Munich…

More than three percent of the world’s population (around 300 million people) are living with a chronic hepatitis B virus (HBV) infection. Having chronic hepatitis B increases the risk for patients to develop liver failure, liver cancer or cirrhosis…

The sixth Munich Epigenetic Spotlight meeting was held at the Stem Cell Center of Helmholtz Munich in Großhadern on Monday 24th October 2022. Keynote speakers were Eileen Furlong from EMBL, Heidelberg, and Yang Shi from the Ludwig Institute for…

Fabian Theis and Ele Zeggini's interview

Timo Müller and his team have been working for many years on the development of new therapeutic options for diabetes and obesity. Among other things, they decoded a brain receptor that plays a crucial role in the regulation of body weight and food…

The first 'Helmholtz Summer School on Chromatin Biology: A hands-on-expedition', organized by the Institute of Epigenetics and Stem Cells (IES) and the Institute of Functional Epigenetics (IFE) in collaboration with Abcam, took place on Campus from…

We are delighted to announce and warmly welcome Dr. Marion Jasnin as new Principal Investigator at the Helmholtz Pioneer Campus.

Lukas Schwalb and his colleagues have succeeded in chemically describing the complex medical substance sodium bituminosulfonate (SBS) as well as its process intermediates. For this study they have involved the online derivatization with…

Prof. Cristina García-Cáceres (second left) receives the DAG research award 2022 for her scientific contribution in the field of obesity research. The prize, she shares with Dr. Anne Lautenbach from the University Clinic Hamburg-Eppendorf, was…

Study provides novel insights on dynamics of blood sugar levels and autoimmunity in early childhood

When and why does type 1 diabetes manifest in children? For the first time, researchers conducted a long-term study on infants and young children…

Helmholtz Munich researchers identify a novel mechanism to modify glucagon receptor signaling outcomes by altering its intracellular localization

“DGfI Young Immunologists Seminar Series”

Since 2016, the annual Summer Internship Program in Epigenetics, Stem Cells, and Artificial Intelligence gives international students the opportunity to work alongside world-leading scientists on original research. Under the supervision of Kurt…

For pioneering research into the development of allergic diseases, Giulia Pagani has received a grant of 61,400 euros from the German Research Foundation (DFG).

Christian Matek, MD, DPhil is the recipient of this year‘s Artur Pappenheim Award of the German Society of Hematology and Medical Oncology (DGHO). The prize was awarded to him during the common annual meeting of the German, Austrian and Swiss…

Over the next five years, the interdisciplinary NEUROCOV consortium will investigate the role of the host-virus interplay in the occurrence of neurological and psychiatric symptoms resulting from COVID-19 as a foundation for new treatment options.

Helmholtz Munich researcher Kristian Unger, head of Translational Bioinformatics at the Department of Radiation Cytogenetics (ZYTO), together with scientists from the LMU Radiation Clinic and the LMU Medical Physics, has developed the AI method…

What exactly are the molecular interactions between the virus causing COVID-19 and its human host? How might our genetic differences cause different disease courses? And how do still-emerging virus variants differ in their host-virus interactions? To…

Offenes Verfahren nach VOB/A §3EU

Surface molecules EGFR and Integrin beta 4 play a key role in this process

Frequently, cancer patients do not die because of their “initial tumor” in a specific organ. Only when individual cells of the primary tumor transform, migrate or colonize…

In September 2022, the art installation "The Garden of Forking Paths" by the artist duo Studio T*SH was revealed at the Helmholtz Diabetes Center. At the end of 2020, Helmholtz Munich launched the "Kunst am Bau" competition. From 125 entries, 15…

The MDSI congratulates the awardees of the MDSI Best Paper of the Year Award 2021. Runner-up goes to first author Mohammad Lotfollahi from ICB!

Offenes Verfahren nach VOB/A §3EU

In October, we kicked off our new project HOPARL at Helmholtz Munich, together with experts and scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI), the Technical University of Munich (TUM), and the University of Würzburg.

Since October 2022, Carolin Daniel heads the new, independent Helmholtz Munich Research Unit ‘Type 1 Diabetes Immunology’ (TDI). Her research, for which she already received numerous awards, focuses on the immunology of diabetes. We talked to her…

For the new Helmholtz Munich Pioneer Campus, an art-on-building competition was held - and the winner has now been announced. Ten artists were asked for creative ideas as part of the anonymous and non-open competition. The goal was to find an…

The ability to reprogram cells holds great promises for regenerative medicine. Cells from the embryo at the beginning of life divide and produce all cell types in the body. What can embryos teach us so that we can generate cells ‘à la carte’ to cure…

They fit in the palm of your hand – tiny mini-labs that researchers at Helmholtz Munich want to use to shape the medicine of tomorrow. “Organ-on-chip” is the key word. This approach combines engineering and biology, not only making it easier to…

Diabetes research: At this year's congress of the European Association for the Study of Diabetes (EASD), Helmholtz Munich scientists received several awards for pioneering ideas and ways to fight the disease.

Kl-based federated diagnostic algorithm efficiently learns across hospitals with data protection compliance

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1
85764 Neuherberg 
Deutschland

Schwelle:                 UVgO

Vergabeart:              Verhandlungsverfahren ohne TW

Laufzeit:         …

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1
85764 Neuherberg 
Deutschland

Schwelle:                 UVgO

Vergabeart:              Verhandlungsverfahren ohne TW

Laufzeit:         …

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1
85764 Neuherberg 
Deutschland

Schwelle:                 UVgO

Vergabeart:              Verhandlungsverfahren ohne TW

Laufzeit:         …

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1
85764 Neuherberg 
Deutschland

Schwelle:                 UVgO

Vergabeart:              Verhandlungsverfahren ohne TW

Laufzeit:         …

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1
85764 Neuherberg 
Deutschland

Schwelle:                 UVgO

Vergabeart:              Verhandlungsverfahren ohne TW

Laufzeit:         …

Helmholtz Munich has been participating in the DigiMed Bayern project of the Bavarian State Ministry of Health and Care (STMGP) since the end of 2018. The goal of the project is to advance digitized medicine in Bavaria. The project has now been…

At the 9th Immunotherapy of Cancer Conference (ITOC), held September 22 to 24, 2022 in Munich, Helmholtz Munich presented preclinical data showing that PH-762, an INTASYL compound targeting PD-1, increases the frequency of a T cell population…

Researchers at Helmholtz Munich are working toward a world without diabetes. They are not doing so alone, but with a network of organizations, hospitals, and pharmaceutical companies. Their goal is to use experts’ knowledge to create something new:…

A team of researchers located at Helmholtz Munich reports on a novel function of vitamin K, which is generally known for its importance in blood clotting. The researchers discovered that the fully reduced form of vitamin K acts as an antioxidant…

Rising temperatures accelerate processes: The simple rule of thumb taught in chemistry classes and known as reaction velocity-temperature-regulation, also applies in a broader sense to the effects of global warming on risk groups and sensitive…

New Publication of Ali Doryab and Otmar Schmid (Schmid Lab, Institute of Lung Health and Immunity) in Advanced Materials

Publication of Ali Doryab and Otmar Schmid (Schmid Lab, LHI) in Advanced Materials

Adrian Fischer, PostDoc at IRBM, received the Helmholtz Munich Best Paper Award (Q2, 2022). He took first place as co-first author of the paper "Neutrophils direct preexisting matrix to initiate repair in damaged tissues" published in Nature…

On September 9 Sonja Heine from the Lab Blank (Molecular & Translational Allergology Group) was awarded the Joachim Ganzer Award for Allergen Immunotherapy at the German Allergy Congress in Wiesbaden, Germany.

Dr. Sarah Kim-Hellmuth, Research Group Leader at the Helmholtz Munich Institute of Translational Genomics will be awarded the Friedmund Neumann Prize 2022 for her groundbreaking work in studying the genetic influence on human gene activity.

New IDC publication by Marcos Rios Garcia, Stephan Herzig and Mauricio Berriel Diaz et al.:

Trip13 depletion in liver cancer induces a lipogenic response contributing to Plin2-dependent mitotic cell death.

New IDC publication by Marcos Rios Garcia, Stephan Herzig and Mauricio Berriel Diaz et al.:

Trip13 depletion in liver cancer induces a lipogenic response contributing to Plin2-dependent mitotic cell death.

Helmholtz Munich was present at the Superbloom Festival on the 3rd and 4th of September at the Olympiapark grounds in Munich.

During her stay in August 2022, Anna Dumitriu ran a workshop with researchers at the Institute for Epigenetics and Stem Cells to share her thoughts and experiences of the creative process underlying her artwork “The Cellular Reprogramming Necklace”.

At Helmholtz Munich, scientists are working to ensure that no child will have to suffer from the autoimmune disease type 1 diabetes in the future.

A team of researchers from Helmholtz Munich, the German Center for Diabetes Research (DZD) and Novo Nordisk have developed a new hormone combination for the future treatment of type 2 diabetes. The scientists have combined the blood sugar-reducing…

Parkinson's disease, formerly known as shaking palsy, is the second most common neurodegenerative disease in Germany after Alzheimer's disease. It affects about 400,000 people in Germany alone and can neither be cured nor can its progression be…

The use of artificial intelligence (AI) in the field of pathology, especially in the early detection of diseases, has increased rapidly in the past decade. However, despite an ever-growing number of publications in the field, only few methods are…

Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, access to pancreatic islets is limited and…

Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…

Even though deep learning has led to improvements, the downstream analysis of live-cell microscopy images remains a bottleneck. Recently, researchers from the Institute of Functional Epigenetics published their open-source and user-friendly software…

Prof. Dr. Anette-Gabriele Ziegler, Director of the Helmholtz Munich Institute of Diabetes Research (IDF) receives this year’s EASD–Novo Nordisk Foundation Diabetes Prize for Excellence. The prize is awarded to honor outstanding contributions to the…

Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium with participation of Dr. Matthias Heinig, researcher at Helmholtz Munich, reports in Science.

A team of researchers located at Helmholtz Munich reports on a novel function of vitamin K, which is generally known for its importance in blood clotting. The researchers discovered that the fully reduced form of vitamin K acts as an antioxidant…

On days with high temperatures, people taking certain medications have an increased risk of heart attack: this was found by a team of researchers led by Alexandra Schneider, PhD, research group leader 'Environmental Risks' at the Helmholtz Munich…

As part of the book series ‘Methods in Molecular Biology’, Springer Nature has released the methods and protocols collection ‘Histone Methyltransferases’. The chapter contributed by Till Bartke and colleagues from the Institute of Functional…

How can we predict the distribution of inhaled medical substances on the human body? And how can we do so with alternative methods without animal testing?

To unravel the effects of the newly approved cholesterol lowering drug Bempedoic Acid on the epigenome, Dr. Bilal Sheikh has been awarded a project grant of the 'Deutsche Forschungsgemeinschaft' (DFG). He and his team will receive funding of 271,000…

To unravel the effects of the newly approved cholesterol lowering drug Bempedoic Acid on the epigenome, Dr. Bilal Sheikh has been awarded a project grant of the 'Deutsche Forschungsgemeinschaft' (DFG). He and his team will receive funding of 271,000…

To unravel the effects of the newly approved cholesterol lowering drug Bempedoic Acid on the epigenome, Dr. Bilal Sheikh has been awarded a project grant of the 'Deutsche Forschungsgemeinschaft' (DFG). He and his team will receive funding of 271,000…

Researchers gain a fundamental insight for epitranscriptomics and immune response. The research group around Vigo Heissmeyer and Taku Ito-Kureha of Helmholtz Munich and Ludwig-Maximilians-Universität München has revealed the essential function of m6A…

The German Federal Ministry of Education and Research (BMBF) is funding research of new treatment strategies for preventing tissue ischemia-reperfusion injury (IRI) as part of the FERROPath consortium. Starting in July 2022, the consortium receives…

As part of the collaborative research center (CRC) ‘Chemical Biology of Epigenetic Modifications’ (SFB 1309), Robert Schneider, Director of the Institute of Functional Epigenetics’ at Helmholtz Munich, receives funding from the German Research…

Erika von Mutius, Director of the Environmental Health Center, and her team receive an Advanced ERC Grant for their research on prevention strategies to curb asthma and allergies in children. ERC Advanced Grants are endowed with up to 2.5 million…

The EU grant “PerForM-REACT” supports an infrastructure in the greater Munich area for pandemic management and prevention. Helmholtz Munich will receive new equipment for a biosafety level 3 laboratory where researchers can conduct important studies…

Mr. Xiao Wu successfully defended his doctoral thesis

Experts from academia and the pharmaceutical industry came together at “The Biological Methylation Conference: Fundamental Mechanism in Human Health and Disease” in Catania to share new exciting results about protein and RNA methylations as well as…

Fabian Theis, Director of the Computational Health Center at Helmholtz Munich, has been accepted for membership in the European Molecular Biology Organization (EMBO). Scientists can only be invited to join EMBO on the recommendation of existing…

To unravel the effects of the newly approved cholesterol lowering drug Bempedoic Acid on the epigenome, Dr. Bilal Sheikh has been awarded a DFG project grant..

Simon Blank (Head of the Molecular and Translational Allergology group) contributed to two chapters (Bee Venom Allergy & Vespid Venom Allergy) of the second edition the "EAACI Molecular Allergology User's Guide", the world’s first comprehensive…

Internationally renowned neurobiologist Magdalena Götz is pursuing important leads in her quest to elucidate the causes of neurological diseases. Together with her team at Helmholtz Munich and Ludwig-Maximilians-Universität München, she has gained…

Every year, millions of people fall ill with Chagas or sleeping sickness. Both diseases are caused by parasites that are spreading from tropical countries to Europe. Researchers have discovered a weak spot in those parasites, which may be a key to a…

Many children suffer from asthma or allergies. Early and effective prevention of these diseases is the declared goal of science. Which research strategies do scientists pursue and what part does cow barn play in this story?

aeroHEALTH announces manuscript acceptance from first joint comprehensive study combining biological effects and physical/chemical analysis of anthropogenic and biogenic secondary organic aerosols in "Environment International".

Internationally renowned neurobiologist Magdalena Götz is pursuing important leads in her quest to elucidate the causes of neurological diseases. Together with her team at Helmholtz Munich and Ludwig-Maximilians-Universität München, she has gained…

Congratulations to Anne Loft and Ana Alfaro!

Congratulations to Anne Loft and Ana Alfaro!

Helmholtz Munich scientist Stephanie Kullmann is awarded this year's Ferdinand Bertram Award of the German Diabetes Society (DDG). With this award, the DDG honors her research on the role of central nervous processes in the prevention and treatment…

Helmholtz Munich scientist Stephanie Kullmann is awarded this year's Ferdinand Bertram Award of the German Diabetes Society (DDG). With this award, the DDG honors her research on the role of central nervous processes in the prevention and treatment…

In a highly competitive procedure, 2 Research Training Groups in Tübingen were approved by the DFG for 5 years of funding.

Details here.

The MedtecLIVE Talent Award 2022 is given to bachelor’s and master’s theses that relate to an innovation, improvement, or new application in medical technology along with its entire value chain.

For his outstanding achievements in the research field “Diabetes and Cancer”, the German Diabetes Society (DDG) awards this year's Werner Creutzfeldt Prize to Helmholtz Munich scientist Stephan Herzig.

For his outstanding achievements in the research field “Diabetes and Cancer”, the German Diabetes Society (DDG) awards this year's Werner Creutzfeldt Prize to Helmholtz Munich scientist Stephan Herzig.

Researchers have succeeded in sequencing and characterizing the entire genome of oat. Compared to other cereals and humans, the oat genome architecture is very complex. Scientists from Helmholtz Munich, Lund University and the ScanOats network…

The German Academic Exchange Service (Deutscher Akademischer Austauschdienst – DAAD) is using funding from the Federal Ministry of Education and Research (BMBF) to extend its promotion of young AI talents in Germany.

Details here.

The Chris McGuigan Symposium took place on 22 April at Cardiff University’s Main Building. The bi-annual awards ceremony celebrates and rewards the work of three scientists who have made a substantial contribution to the field of drug discovery.

A clinical study confirms the success of a novel technology developed by Helmholtz Munich and the Technical University of Munich (TUM) for the evaluation of the treatment of psoriasis. With the new method, doctors can look deeper into the skin of…

Minaskan N / Wiedemann T ... Pellegata NS. A tumor-borne Ang-2/Tie-2 autostimulatory loop controls tumorigenesis. EMBO Mol Med. 2022 Mar 10:e14364

Minaskan N / Wiedemann T ... Pellegata NS. A tumor-borne Ang-2/Tie-2 autostimulatory loop controls tumorigenesis. EMBO Mol Med. 2022 Mar 10:e14364

https://academic.oup.com/bib/article/23/2/bbab535/6492643?login=true

G-protein coupled receptor marks bronchiole remodeling by distal Keratin 5+ basal progenitor cells

Fostering interdepartmental and cross-institutional research - congrats to Boyan Bonev for his ERC Consolidator Grant to understand the regulatory logic of lineage specification in the developing cortex.

Prof. Dr. Ralf Zimmermann receives honorary doctorate from the University of Eastern Finland.

This work describes the cell-free production, transient protein-modification, and time-resolved proteomics analysis of bacteriophages targeted against clinically relevant bacteria.

For his outstanding achievements in the research field “Diabetes and Cancer”, the German Diabetes Society (DDG) awards this year's Werner Creutzfeldt Prize to Helmholtz Munich scientist Stephan Herzig.

Postdoc position in the new to establish single-cell and quantitative stem cell biology lab.

Two newly acquired ERC Advanced Grants support the cutting-edge research of Munich Helmholtz scientists Heiko Lickert and Fabian Theis. The researchers are international stars in the fields of diabetes and artificial intelligence. The funding will…

Details here.

Two newly acquired ERC Advanced Grants support the cutting-edge research of Munich Helmholtz scientists Heiko Lickert and Fabian Theis. The researchers are international stars in the fields of diabetes and artificial intelligence. The funding will…

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Non quam nostram quidem, inquit Pomponius iocans; Scrupulum, inquam, abeunti; Itaque ab his ordiamur. Beatus sibi videtur esse moriens.Hic nihil fuit, quod quaereremus. Sed quae tandem ista…

Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…

Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…

Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…

“Infection immunity in COVID-19 and beyond”

“Infection immunity in COVID-19 and beyond”

The EU funds a new Innovative Training Network (ITN) in the field of DNA replication, cell fate, and cancer with Helmholtz Munich as a beneficiary. The ITN will investigate the role of DNA replication as a determinant of cell fate and cancer.

Details here.

By the use of fetal magnetic resonance imaging (MRI), scientists and physicians from Helmholtz Munich and LMU University Hospital Munich have discovered a reduction in lung volume in fetuses from mothers with an uncomplicated SARS-CoV-2 infection…

The sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose.

Research carried out at Helmholtz Munich has shown that…

The sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose.

Research carried out at Helmholtz Munich has shown that…

Prof. Dr. Julia Schnabel is invited as keynote speaker at MIDL 2022.

At each event, two Principal Investigators (PIs) of MIBE working in related research areas will provide exciting insights into their research. After the talks which take around 90 minutes, there is plenty of time for networking.

Dates: Friday, 25th March 2022 & Saturday 26th March 2022

Location: TranslaTUM, Munich & online

Helmholtz Munich obtains two ERC Consolidator Grants: Timo Müller from the Institute for Diabetes and Obesity with "TRUSTED", and Ben Engel, formerly of the Helmholtz Pioneer Campus, with "cryOcean". They are among the successful 12 percent to…

From October 17th to 20th October 2022, the conference "EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the Genome" will take place in Granada, Spain. The registration will open soon.

The Corona pandemic showed us clearly that to be able to find, understand and evaluate good health information is an important prerequisite for protecting ourselves from fake news. It is therefore important to begin by strengthening the health…

Article in Nature Communications: Reduction of PRMT7 protein could stop tissue damage

Replacing sick or damaged cells with healthy cells: this is a major goal of regenerative medicine. One of the most promising approaches is cellular reprogramming, whereby one cell type in our body converts to another cell type. Research carried out…

Details here.

Replacing sick or damaged cells with healthy cells: this is a major goal of regenerative medicine. One of the most promising approaches is cellular reprogramming, whereby one cell type in our body converts to another cell type. Research carried out…

Reversing injury or disease is a major objective in research towards regenerative medicine. Replacing sick or damaged cells with healthy cells in order to repair damaged tissue is one of the most impactful strategies towards that goal. For that, a…

Details here.

It only takes a blood test to detect the autoimmune disease type 1 diabetes in children at an early stage and, thus, prevent severe metabolic derailments. Helmholtz Munich offers the world's largest population-based screening for type 1 diabetes in…

Topic: "Allergic Rhinitis" in BR24 Gesundheitsmagazin

Lukas Heumos and team have won the campusSOURCE Award 2022 for cookietemple tool.

Together with five other Helmholtz centers, we develop solutions for a healthier society in a network of cutting-edge biomedical research that is unique in Europe. Our mission is to translate research results as quickly as possible into advances for…

Voluntary fasting, for example interval fasting, is beneficial to health for many people, depending on their individual condition. For example, controlled periods of starvation can prevent and improve diseases such as diabetes and obesity.…

We are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.

We are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.

Data is not only the answer to numerous questions in the business world; the same applies to biomedical research. In order to develop new therapies or prevention strategies for diseases, scientists need more and better data, faster and faster.…

According to a new study led by Ulrike Protzer, a breakthrough infection after two vaccinations achieves the same protective effect as an additional booster vaccination. According to the study by Helmholtz Munich, LMU and TUM, the decisive factor for…

Squidpy: a scalable framework for spatial omics analysis

Single-cell data in context

Lotfollahi et al. present scArches, a method to contextualize new single-cell datasets within existing reference atlases without the need to share raw data.

Volume 40 Issue 1, January 2022

The Epstein-Barr virus (EBV) has been known for some time to play a part in a range of diseases. A current US study has now shown a close link between EBV and multiple sclerosis. Scientists at Helmholtz Munich and DZIF are already working on…

Medicine is on the verge of another revolution: Artificial intelligence supports doctors in analyzing X-ray and ultrasound images and in improving diagnostics and treatment. Researchers in Germany are also successfully working on novel solutions, and…

How AI is revolutionizing medicine

Therapy-resistant head and neck tumors and their relapses exhibit molecular profiles that, as now discovered, indicate marked tumor heterogeneity and molecular dynamics within one patient. The composition of tumor subpopulations influenced by therapy…

The interplay of genetics and epigenetics is a long-sought riddle in the development of diseases. Researchers from Helmholtz Munich and the Imperial College London discovered novel interactions. Their findings improve our knowledge about…

Link to publication.

Helmholtz Munich starts the new year with a triple success: Together with early-career scientists, the research center acquires three ERC Starting Grants from the European Research Council (ERC). The researchers have the vision to discover…

The possibility to generate any cell type from a differentiated, somatic cell can advance cell-replacement therapies and holds great promises to regenerative medicine. Therefore, understanding the molecular mechanisms underlying cell-fate changes…

Link to paper here.

Michael Schloter has been elected a member of the Bavarian Academy of Sciences for the committee “Forum Ecology”. This is the third membership of Helmholtz Munich researchers in the Academy, highlighting the expertise of our scientists and the…

We are delighted to announce the 10th International Workshop on Biomedical Image Registration (WBIR2022) that will be hosted in Munich, Germany, from 10th to 12th July 2022.

By Anirban Mukhopadhyay

Podcast is a great clinical culture for Knowledge dissemination, constructive arguments & deep discussions. One more way in which the MICCAI community is different from those who we serve. Introducing "AI-ready Healthcare",…

Vaccines against the SARS-CoV-2 virus have been made possible by an unprecedented worldwide partnership. However, medications against Covid-19 have yet seen only partial success. With the support of the Bavarian Research Foundation, a Munich research…

Scientists at Helmholtz Zentrum München have discovered a new signaling mechanism for the regulation of energy metabolism in brown adipose tissue.

Scientists at Helmholtz Zentrum München have discovered a new signaling mechanism for the regulation of energy metabolism in brown adipose tissue.

The artwork "Auf den Schultern von Riesen" (Standing on the shoulders of giants) by Heike Weber and Walter Eul will illuminate the tower of the future conference center on Neuherberg Campus. The artist duo made first place in the competition "Light…

Biomedical imaging is the window through which we can look into organisms. It allows us to see cells, their behavior and localization that would otherwise be hidden. Tracking very few cells over time without damaging them is a key challenge in health…

Das Naturkundemuseum Bayern 'BIOTOPIA' veranstaltete am 2. Dezember ein Online-Event zum Thema "Künstliche Intelligenz im Gesundheitswesen: Anwendungen, Herausforderungen, Zukunftspotenziale". Vom Zentrum mit dabei sind unser CEO Matthias Tschöp,…

For the first time, scientists based at Helmholtz Munich and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). The finding, published in the journal Nature, will…

How can we better diagnose blood diseases? A research group led by Helmholtz Munich aims to answer this question with artificial intelligence (AI). Their goal is to facilitate the time-consuming analysis of bone marrow cells under the microscope. The…

Presentation of the Hamburg Science Prize

Obesity, diabetes and gastrointestinal cancer are frequently linked to an unhealthy diet. However, the molecular mechanisms responsible for this are not fully understood. Researchers at Helmholtz Munich have gained some new insights that help to…

„WISSEN.SCHAFFT.GESUNDHEIT“ – unter diesem Motto präsentierten hochrangige Vertreter:innen des Zentrums am Donnerstag, 18. November, im IMAX-Kino des Deutschen Museums unsere Vision und Forschungshighlights der Öffentlichkeit.

For the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…

For the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…

Just in time for World Diabetes Day, the national diabetes information portal www.diabinfo.de has announced that it has expanded its content offering. In addition to German and Turkish, information for people with diabetes and diabetes prevention is…

The 100th anniversary of the discovery of insulin is a milestone in diabetes research and insulin continues to be a lifesaver for many people. At the same time, the International Diabetes Federation predicts a rise in the number of diabetes cases to…

Horst Zitzelsberger and Daniel Samaga from the Research Unit Radiation Cytogenetics, together with researchers from the LMU Hospital and the former Clinical Cooperation Group "Personalized Radiotherapy in Head and Neck Tumors", succeeded in renewing…

Germany is not sufficiently prepared for the health challenges posed by climate change. Despite a growing awareness among political leaders for the urgency of the situation, concrete measures to avoid climate-related health risks and to combat…

Moritz Thomas, who is pursuing a PhD from the Institute of AI Health’s Marr Lab, has won the first prize for his poster at the 2021 German Stem Cell Network annual conference. The 9th edition of the conference, which took place from October 6-8, was…

Understanding cellular architecture is essential for understanding biology. Electron microscopy (EM) uniquely visualizes cellular structures with nanometer resolution. However, traditional methods, such as thin-section EM or EM tomography, have…

Vasilis Ntziachristos receives this year's Karl Heinz Beckurts Prize for his outstanding achievements and pioneering work in the field of biomedical imaging. The BioNTech and CureVac founders were also honored with special prizes at the award…

The Academy of Sciences and Humanities in Hamburg is honouring Fabian Theis as a pioneer in the field of Artificial Intelligence in biomedical applications, above all in the area of single-cell biology.