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Helmholtz Munich | Matthias Tunger Photodesign

Dr. Adrian Fischer

IRBM
+498931871592Email meBuilding/Room: Großhadern/ 2nd floor/ B.301

My mission is to identify basic patho mechanisms of organ fibrosis. I investigate this in various in vitro high throughput assays, ex vivo tissue explants or preclinical in vivo models. With the better mechanistic understanding of biology, the translatability into potential therapeutic applications is always in focus for me.

One of my research focuses is on organ surfaces, which represent a unique niche for diverse populations of cells and also elements of extra cellular matrix (ECM). These cells and ECM are responsible for various pathologies such as whole organ adhesions after abdominal surgery.

Another field that interests me is the movement of ECM in organ lesions. I am interested in which matrix elements are transported, how they are processed and by whom, and what the effects of the transported matrix are in the wounds. Exciting questions here are how the ECM influences the fate of the embedded cells and thus decides programs between pathology or regeneration.

My mission is to identify basic patho mechanisms of organ fibrosis. I investigate this in various in vitro high throughput assays, ex vivo tissue explants or preclinical in vivo models. With the better mechanistic understanding of biology, the translatability into potential therapeutic applications is always in focus for me.

One of my research focuses is on organ surfaces, which represent a unique niche for diverse populations of cells and also elements of extra cellular matrix (ECM). These cells and ECM are responsible for various pathologies such as whole organ adhesions after abdominal surgery.

Another field that interests me is the movement of ECM in organ lesions. I am interested in which matrix elements are transported, how they are processed and by whom, and what the effects of the transported matrix are in the wounds. Exciting questions here are how the ECM influences the fate of the embedded cells and thus decides programs between pathology or regeneration.

Fields of Work and Expertise

 matrix biologyorgan fibrosisproteomicsdrug target identification 

Professional Background

since 2022

Junior group leader, IRBM, Helmholtz Center Munich, Germany

2017-2022

Postdoctoral researcher, Helmholtz Center Munich, Germany

2012-2016

PhD in Biochemistry and Cell Signaling, University of Freiburg, Germany

Honors, Awards and Conferences

  • 2022
    Helmholtz Munich Best Paper Award (Q2, 2022), Helmholtz Zentrum München, Germany

  • 2017 - 2019
    Postdoctoral Fellowship Program III 2018, Helmholtz Zentrum München, Germany

  • 2013
    "Best Foundational Advance Overgraduate" IGEM Competition 2013

  • 2010
    "Best Health or Medicine Project" IGEM Competition 2010

Best Paper Award Adrian Fischer
Helmholtz Munich | © Andreas Weiss