Dr. Yuval Rinkevich
Director, IRBM“Regenerative medicine encompasses our scientific desire to understand and capitalize on nature’s tools for healing. Our goal is to uncover novel tissue repair mechanisms that can be exploited to restore diseased and injured tissues..”
“Regenerative medicine encompasses our scientific desire to understand and capitalize on nature’s tools for healing. Our goal is to uncover novel tissue repair mechanisms that can be exploited to restore diseased and injured tissues.”
Academic Pathway & Research Area
Dr. Rinkevich has been working at the cutting edge of our understanding of tissue/organ repair and regeneration for over 20 years. His passion and commitment to understanding healing responses and tissue rejuvenation has led his career track from the point of obtaining his PhD degree from the Technion-Israel Institute of Technology, where he studied whole body regeneration from single blood vessels in Protochordates. Dr Rinkevich moved to Stanford University in the US where he investigated pivotal cellular lineages and stem cells in coordinating mammalian tissue repair and regeneration. His work at Stanford projected Dr Rinkevich into the forefront of the tissue repair field, uncovering the role of Engrailed-1 positive cells in the transition from scarless to scar forming tissue responses.
Today Dr Rinkevich is the Director of the Helmholtz Institute of Regenerative Biology and Medicine at the Helmholtz Center, Munich, Germany. His lab fuses a focus on basic biology, continuing to push forward our understanding of tissue/organ repair and regeneration, with a vision to applying these findings to drug development strategies and translation to the clinic. Publication in high impact journals including Nature and Science, numerous patents and supported by prestigious awards such as the ERC Consolidator Grant, highlight the quality of his team’s work. Dr Rinkevich’s latest work describing the role of fascia and transfer of extracellular matrix in tissue scarring and fibrosis in multiple organ systems is reinventing the way we look at tissue repair and regeneration. These findings provide a new perspective on the potential for clinical intervention, opening our minds to a revolution in antifibrotic therapy, a clinical area impacting fields of medicine from oncology to hepatology and pulmonology, and the potential to prevent and potentially resolve fibrotic disease.
Fields of Work and Expertise
Developmental Biology Stem Cell BiologyPathologyTissue Repair and Regeneration Fibrosis ScarringHealing Extra-cellular Matrix
Professional Background
Director, Institute of Regenerative Biology and Medicine
Tenured Principal Investigator / Helmholtz Zentrum München
PI, Helmholtz Center Munich
Basic Life Science Research Associate, Stanford University
Post doctorate, Stanford University
Doctorate in Biology (PhD), Israel Institute of Technology
Master of Science (MSc), Israel Institute of Technology
Bachelor of Science (BSc), Faculty of Life Sciences, Tel-Aviv University
Honors and Awards
HFSP Career Development Award
Honors and Awards

Employee of the Year Award

The Innovative Research Award

The Research Excellence Award
Publications
Read more2022 Meeting abstract in Wound repair and regeneration
Clonal analysis of mesothelium during healthy, developing, and injured conditions.
2022 Scientific Article in Journal of Investigative Dermatology, The
Therapeutic silencing of p120 in fascia fibroblasts ameliorate tissue repair.
2022 Scientific Article in Pharmaceutics
Continuous NPWT regulates fibrosis in murine diabetic wound healing.
2022 Scientific Article in Developmental Biology
Transcriptome landscapes that signify Botrylloides leachi (Ascidiacea) torpor states.
2022 Scientific Article in Cold Spring Harbor Perspectives in Biology
Diversity of fibroblasts and their roles in wound healing.
2022 Scientific Article in Journal of Visualized Experiments
Visualizing scar development using SCAD assay - An Ex-situ skin scarring assay.
2022 Editorial in Journal of Investigative Dermatology, The