All Publications
2025 Scientific Article in OncoImmunology OncoImmunology 14:2457797 (2025)
Metabolic heterogeneity in tumor cells impacts immunology in lung squamous cell carcinoma.
2025 Scientific Article in EMBO Reports EMBO Rep. 26, 810-835 (2025)
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization.
2024 Scientific Article in Cellular & Molecular Immunology Cell. Mol. Immunol., DOI: 10.1038/s41423-024-01219-w (2024)
CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells.
2024 Scientific Article in Biomarker Insights Biomark. Insights 19:11772719241274017 (2024)
The chromosome passenger complex (CPC) components and its associated pathways are promising candidates to differentiate between normosensitive and radiosensitive ATM-mutated cells.
2024 Scientific Article in PLoS Computational Biology PLoS Comput. Biol. 20:e1012488 (2024)
Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network.
2024 Review in Infection - A Journal of Infectious Disease Infection, DOI: 10.1007/s15010-024-02386-8 (2024)
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome.
2024 Scientific Article in npj Precision Oncology npj Precis. Oncol. 8:116 (2024)
Metabolic pathway-based subtypes associate glycan biosynthesis and treatment response in head and neck cancer.
2024 Scientific Article in Scientific Reports Sci. Rep. 14:21864 (2024)
Dipeptide metabolite, glutamyl-glutamate mediates microbe-host interaction to boost spermatogenesis.
2024 Scientific Article in Metabolism: clinical and experimental Metabolism 161:156034 (2024)
Inter-organ cross-talk in human cancer cachexia revealed by spatial metabolomics.
2024 Review in Heliyon Heliyon 10:e36659 (2024)
Decoding the genomic enigma: Approaches to studying extrachromosomal circular DNA.
2024 Scientific Article in Virology Journal Virol. J. 21:139 (2024)
Evaluation of novel Epstein-Barr virus-derived antigen formulations for monitoring virus-specific T cells in pediatric patients with infectious mononucleosis.
2024 Scientific Article in ACS applied materials & interfaces ACS Appl. Mater. Interfaces 16, 37275-37287 (2024)
Light-induced transformation of virus-like particles on TiO2.
2024 Scientific Article in Journal of Controlled Release J. Control. Release 372, 522-530 (2024)
Tuning the photophysical properties of cyanine by barbiturate functionalization and nanoformulation for efficient optoacoustics- guided phototherapy.
2024 Scientific Article in Science Science 385:eadk4898 (2024)
A metabolic dependency of EBV can be targeted to hinder B cell transformation.
2024 Scientific Article in BMJ Open Respiratory Research BMJ Open Respir. Res. 11:e001762 (2024)
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
2024 Scientific Article in Nature Communications Nat. Commun. 15:1960 (2024)
Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization.
2024 Scientific Article in British Journal of Cancer BJC Br. J. Cancer 130, 1036-1045 (2024)
Metabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer.
2024 Scientific Article in Cells Cells 13:13 (2024)
Fully human herpesvirus-specific neutralizing IgG antibodies generated by EBV immortalization of splenocytes-derived from immunized humanized Mice.
2024 Scientific Article in Nature Communications Nat. Commun. 15:414 (2024)
Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.
2023 Scientific Article in Cells Cells 12:22 (2023)
A mouse model to study the pathogenesis of γ-herpesviral infections in germinal center B cells.
2023 Scientific Article in Biomedicines Biomedicines 11:2892 (2023)
SARS-CoV-2 and Epstein-Barr Virus-like particles associate and fuse with extracellular vesicles in virus neutralization tests.
2023 Scientific Article in Gastroenterology Gastroenterology 165, 187-200.e7 (2023)
ARBM101 (Methanobactin SB2) drains excess liver copper via biliary excretion in Wilson's disease rats.
2023 Review in Archives of Computational Methods in Engineering Arch. Comp. Met. Engineering 31, 615-622 (2023)
Deep learning approaches applied to image classification of renal tumors: A systematic review.
2023 Scientific Article in Cancer Nanotechnology Cancer Nanotechnol. 14:36 (2023)
Bacterial outer membrane vesicles as cationic dye carriers for optoacoustics-guided phototherapy of cancer.
2023 Scientific Article in Gut Microbes Gut Microbes 15:2271597 (2023)
Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models.
2023 Scientific Article in ACS Nano ACS Nano 17, 21056-21072 (2023)
Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice.
2023 Scientific Article in Infection - A Journal of Infectious Disease Infection, DOI: 10.1007/s15010-023-02116-6 (2023)
Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.
2023 Scientific Article in npj Precision Oncology npj Precis. Oncol. 7:114 (2023)
Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma.
2023 Review in Autoimmunity Reviews Autoimmun. Rev. 22:103452 (2023)
Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center.
2023 Scientific Article in Stem Cell Reports Stem Cell Rep. 18, 1972-1986 (2023)
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.
2023 Scientific Article in Nature Communications Nat. Commun. 14, 16:5799 (2023)
Translating genomic tools to Raman spectroscopy analysis enables high-dimensional tissue characterization on molecular resolution.
2023 Scientific Article in Frontiers in Medicine Front. Med. 10:1194754 (2023)
Fighting Post-COVID and ME/CFS – development of curative therapies.
2023 Scientific Article in Nature Biotechnology Nat. Biotechnol. 41, 1734–1745 (2023)
Genetically encoded barcodes for correlative volume electron microscopy.
2023 Scientific Article in Cellular and Molecular Gastroenterology and Hepatology Cell. Mol. Gast. Hept. 16, 201-221 (2023)
Hepatitis B virus targets lipid transport pathways to infect hepatocytes.
2023 Scientific Article in Vaccines Vaccines 11:14 (2023)
Assessing the efficacy of VLP-based Vaccine against Epstein-Barr Virus using a rabbit model.
2023 Scientific Article in Hypertension Hypertension 80, 1555-1567 (2023)
Primary aldosteronism: Spatial multi-omics mapping of genotype-dependent heterogeneity and tumor expansion of aldosterone-producing adenomas.
2023 Scientific Article in ACS Nano ACS Nano 17, 16396-16411 (2023)
Patterns of carbon-bound exogenous compounds impact disease pathophysiology in lung cancer subtypes in different ways.
2023 Scientific Article in JCI insight JCI insight 8:18 (2023)
Metabolic heterogeneity in adrenocortical carcinoma impacts patient outcomes.
2023 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 22:217 (2023)
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.
2023 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 120:e2211281120 (2023)
The autophagy machinery interacts with EBV capsids during viral envelope release.
2023 Scientific Article in EMBO Reports EMBO Rep. 24:e55981 (2023)
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.
2023 Scientific Article in Scientific Reports Sci. Rep. 13:12594 (2023)
A pilot radiometabolomics integration study for the characterization of renal oncocytic neoplasia.
2023 Scientific Article in Pathogens Pathogens 12:21 (2023)
Newly designed poxviral promoters to improve immunogenicity and efficacy of MVA-NP candidate vaccines against lethal influenza virus infection in mice.
2023 Scientific Article in eLife eLife 12:34 (2023)
Succinate mediates inflammation-induced adrenocortical dysfunction.
2023 Scientific Article in British Journal of Cancer BJC Br. J. Cancer 128, 1369-1376 (2023)
Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks.
2023 Scientific Article in Clinical Chemistry Clin. Chem. 69, 149-159 (2023)
In situ metabolomics of cortisol-producing adenomas.
2023 Scientific Article in Nature Cancer Nat. Cancer 4, 81–95 (2023)
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
2022 Scientific Article in Oncology Oncology 101, 126-133 (2022)
MALDI mass spectrometry imaging-Diagnostic pathways and metabolites for renal tumor entities.
2022 Scientific Article in Cancers Cancers 14:5485 (2022)
T cells directed against the metastatic driver chondromodulin-1 in ewing sarcoma: Comparative engineering with CRISPR/Cas9 vs. retroviral gene transfer for adoptive transfer.
2022 Scientific Article in JCI insight JCI insight 7:e162138 (2022)
Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:889836 (2022)
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.
2022 Scientific Article in Oncology Research and Treatment Oncol. Res. Treat. 45, 2, 162-162 (2022)
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
2022 Scientific Article in PNAS Nexus PNAS Nexus 1:pgac045 (2022)
Quantitation of SARS-CoV-2 neutralizing antibodies with a virus-free, authentic test.
2022 Scientific Article in Nature Communications Nat. Commun. 13:4689 (2022)
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:913275 (2022)
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
2022 Review in Frontiers in Microbiology Front. Microbiol. 13:955603 (2022)
Strategies of Epstein-Barr virus to evade innate antiviral immunity of its human host.
2022 Scientific Article in PLoS ONE PLoS ONE 17:e0271630 (2022)
Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2200512119 (2022)
EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus-infected B cells.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 66:101616 (2022)
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5104 (2022)
A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.
2022 Nature Communications Nat. Commun. 13:6009 (2022)
Author Correction: A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity (Nature Communications, (2022), 13, 1, (5104), 10.1038/s41467-022-32507-6).
2022 Scientific Article in EBioMedicine EBioMedicine 85:104296 (2022)
The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling.
2022 Scientific Article in European Journal of Cancer Eur. J. Cancer 176, 41-49 (2022)
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.
2022 Scientific Article in Cancers Cancers 14:3745 (2022)
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.
2022 Scientific Article in Laboratory Investigation Lab. Invest. 102, 1400-1405 (2022)
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.
2022 Scientific Article in International Journal of Biological Sciences Int. J. Biol. Sci. 18, 5230-5240 (2022)
Inhibition of APOE potentiates immune checkpoint therapy for cancer.
2022 Scientific Article in Biomedicines Biomedicines 10:825 (2022)
A novel anti-CD73 antibody that selectively inhibits membrane 2 CD73 shows antitumor activity and induces tumor immune escape.
2022 Scientific Article in Leukemia Leukemia 36, 2281–2292 (2022)
PARP14 is a novel target in STAT6 mutant follicular lymphoma.
2022 Scientific Article in Cancers Cancers 14:1763 (2022)
MALDI mass spectrometry imaging—prognostic pathways and metabolites for renal cell carcinomas.
2022 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 157, 595–605 (2022)
A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS.
2022 Scientific Article in BMC Cancer BMC Cancer 22:254 (2022)
Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF.
2022 Scientific Article in Cancer Cell Cancer Cell 40, 639-655.e13 (2022)
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.
2022 Scientific Article in Annals of Translational Medicine Ann. Transl. Med. 10:625 (2022)
A 3D multi-modal intelligent intervention system using electromagnetic navigation for real-time positioning and ultrasound images: A prospective randomized controlled trial.
2022 Scientific Article in Cancer communications Cancer Comm. 42, 517-535 (2022)
Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients.
2022 Scientific Article in Journal of Enzyme Inhibition and Medicinal Chemistry J. Enzyme Inhib. Med. Chem. 37, 592-596 (2022)
First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors.
2022 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 12:e666 (2022)
The synergism of spatial metabolomics and morphometry improves machine learning-based renal tumour subtype classification.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1589 (2022)
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19.
2022 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 117:11 (2022)
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 473-486.e9 (2022)
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 2865-2877 (2022)
Spatial metabolomics identifies distinct tumor-specific subtypes in gastric cancer patients.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 329-345.e8 (2022)
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 1038-1052 (2022)
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2022 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 50, 490-511 (2022)
Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1.
2022 Scientific Article in Journal of Pathology, The J. Pathol. 256, 202-213 (2022)
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients.
In: (European Conference on Biomedical Optics, 20–24 June 2021, Munich Germany). 2021. DOI: 10.1117/12.2615998 ( ; 11923)
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.
2021 Scientific Article in mBio mBio 12:e0224321 (2021)
The Epstein-Barr virus oncogene EBNA1 suppresses natural killer cell responses and apoptosis early after infection of peripheral B cells.
2021 Scientific Article in PLoS Genetics PLoS Genet. 17:e1009951 (2021)
MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells.
2021 Review in Frontiers in Oncology Front. Oncol. 11:771335 (2021)
Various uses of PD1/PD-L1 inhibitor in oncology: Opportunities and challenges.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:796379 (2021)
Immunoinformatic analysis reveals antigenic heterogeneity of Epstein-Barr virus is immune-driven.
2021 Scientific Article in British Journal of Haematology Br. J. Haematol., DOI: 10.1111/bjh.17990 (2021)
The molecular ontogeny of follicular lymphoma: Gene mutations succeeding the BCL2 translocation define common precursor cells.
2021 Scientific Article in EJNMMI Research EJNMMI Res. 11:120 (2021)
Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma.
2021 Scientific Article in Cellular Microbiology Cell. Microbiol. 23:e13399 (2021)
Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.
2021 Scientific Article in Cell Discovery Cell Discov. 7:105 (2021)
Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV.
2021 Scientific Article in Physics & Imaging in Radiation Oncology Phys. Imag. Radiat. Oncology 20, 11-16 (2021)
In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice.
2021 Scientific Article in EMBO Reports EMBO Rep.:e53007 (2021)
PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.
2021 Scientific Article in Cancer Research Cancer Res. 81, 5862-5875 (2021)
Patterns of carbon-bound exogenous compounds in lung cancer patients and association with disease pathophysiology.
2021 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 49, 10657–10676 (2021)
Modulation of alternative splicing during early infection of human primary B lymphocytes with Epstein-Barr virus (EBV): A novel function for the viral EBNA-LP protein.
2021 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 11:e547 (2021)
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1202-1216 (2021)
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 13:e13490 (2021)
Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101334 (2021)
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
2021 Scientific Article in Cell Death & Disease Cell Death Dis. 12:723 (2021)
Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma.
2021 Scientific Article in Molecular Immunology Mol. Immunol. 138, 128-136 (2021)
Context-dependent regulation of immunoglobulin mutagenesis by p53.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1685-1700.e9 (2021)
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
2021 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 185, 179-191 (2021)
Mass spectrometry imaging identifies metabolic patterns associated with malignant potential in pheochromocytoma and paraganglioma.
2021 Scientific Article in Science Signaling Sci. Signal. 14:eabc1648 (2021)
ERK phosphorylation is RAF independent in naïve and activated B cells but RAF dependent in plasma cell differentiation.
2021 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 413, 5619-5632 (2021)
Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA).
2021 Scientific Article in Nature Communications Nat. Commun. 12:2999 (2021)
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
2021 Scientific Article in Diabetologia Diabetologia 64, 1850-1865 (2021)
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
2021 Scientific Article in Photoacoustics Photoacoustics 22:100263 (2021)
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.
2021 Scientific Article in Blood Blood 137, 3225-3236 (2021)
CD27 is required for protective lytic EBV antigen specific CD8+ T cell expansion.
2021 Scientific Article in Frontiers in Oncology Front. Oncol. 11:612354 (2021)
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.
2021 Scientific Article in Journal of Clinical Oncology - JCO J. Clin. Oncol. 39, 1468-1478 (2021)
HER2 expression, test deviations, and their impact on survival in metastatic gastric cancer: Results from the prospective multicenter VARIANZ study.
2021 Scientific Article in Chemosphere Chemosphere 276:130143 (2021)
Characteristics of chemical profile, sources and PAH toxicity of PM2.5 in beijing in autumn-winter transit season with regard to domestic heating, pollution control measures and meteorology.
2021 Scientific Article in Advanced healthcare materials Adv. Healthc. Mater. 10:e2002115 (2021)
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.
2021 Nature Nature 592:E1 (2021)
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 28, 213-224 (2021)
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.
2021 Scientific Article in Journal of Hepatology J. Hepatol. 75, 74-85 (2021)
Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection.
2021 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 49, 3217-3241 (2021)
Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation.
2021 Scientific Article in eLife eLife 10:e62161 (2021)
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.
2021 Scientific Article in PLoS Pathogens PLoS Pathog. 17:e1009117 (2021)
Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1111 (2021)
Notch2-mediated plasticity between marginal zone and follicular B cells.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0248594 (2021)
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.
2021 Scientific Article in mBio mBio 12:e03440-20 (2021)
Multiple viral micrornas regulate interferon release and signaling early during infection with epstein-barr virus.
2021 Scientific Article in Frontiers in Oncology Front. Oncol. 10:614876 (2021)
PD-1 blockade aggravates Epstein–Barr Virus+ post-transplant lymphoproliferative disorder in humanized mice resulting in central nervous system involvement and CD4+ T cell dysregulations.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 45:101147 (2021)
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.
2021 Scientific Article in Nature Nature 590, 326–331 (2021)
Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000898 (2021)
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 833-844.e5 (2021)
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.
2021 Scientific Article in Molecular Oncology Mol. Oncol. 15, 1040-1053 (2021)
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.
2021 Scientific Article in Breast Care Breast Care 16, 523-531 (2021)
PITX2 DNA-methylation: Predictive versus prognostic value for anthracycline-based chemotherapy in triple-negative breast cancer patients.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000924 (2021)
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.
2021 Scientific Article in European Radiology Eur. Radiol. 31, 4175–4183 (2021)
Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice.
2021 Scientific Article in Infection - A Journal of Infectious Disease Infection 49, 63–73 (2021)
First results of the "Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)".
2021 Scientific Article in International Journal of Radiation Oncology, Biology, Physics Int. J. Radiat. Oncol. Biol. Phys. 109, 76-83 (2021)
Normal tissue response of combined temporal and spatial fractionation in proton minibeam radiation therapy.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0243462 (2020)
A practical guide to unbiased quantitative morphological analyses of the gills of rainbow trout (Oncorhynchus mykiss) in ecotoxicological studies.
2020 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 8:570305 (2020)
Circ-ZDHHC5 accelerates esophageal squamous cell carcinoma progression in vitro via miR-217/ZEB1 axis.
2020 Scientific Article in European Urology Open Science Eu. Urol. Open Sci. 22, 88-96 (2020)
In situ metabolomics expands the spectrum of renal tumours positive on 99mTc-sestamibi single photon emission computed tomography/computed tomography examination.
2020 Scientific Article in Hypertension Hypertension 76, 1769-1777 (2020)
Effect of dietary sodium modulation on pig adrenal steroidogenesis and transcriptome profiles.
2020 Review in Frontiers in Oncology Front. Oncol. 10:575037 (2020)
Emerging landscapes of tumor immunity and metabolism.
2020 Review in Animal reproduction Anim. Reprod. 17:e20200064 (2020)
A decade of experience with genetically tailored pig models for diabetes and metabolic research.
2020 Scientific Article in Biomarker Research Biomark. Res. 8:46 (2020)
Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL.
2020 Scientific Article in Communications Biology Comm. Biol. 3:628 (2020)
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
2020 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:6832 (2020)
Chronic occupational exposure to ionizing radiation induces alterations in the structure and metabolism of the heart: A proteomic analysis of human formalin-fixed paraffin-embedded (FFPE) cardiac tissue.
2020 Scientific Article in Analytica Chimica Acta Anal. Chim. Acta 1134, 125-135 (2020)
Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS.
2020 Scientific Article in Molecular Therapy-Oncolytics Mol. Ther.-Oncolytics 18, 504-524 (2020)
CAR-T cells targeting Epstein-Barr virus gp350 validated in a humanized mouse model of EBV infection and lymphoproliferative disease.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:14461 (2020)
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.
2020 Scientific Article in American Journal of Cancer Research Am. J. Cancer Res. 10, 1785-1792 (2020)
High levels of KLK7 protein expression are related to a favorable prognosis in triple-negative breast cancer patients.
2020 Other: Opinion in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 8, 733-734 (2020)
A multi-test strategy for adrenal tumours.
2020 Scientific Article in Angewandte Chemie - Internationale Edition Angew. Chem.-Int. Edit. 132, 17600-17603 (2020)
Morphometric cell classification for single-Cell MALDI-mass spectrometry imaging.
2020 Scientific Article in Journal of Translational Medicine J. Transl. Med. 18:242 (2020)
Evaluation of T-activated proteins as recall antigens to monitor Epstein-Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting.
2020 Scientific Article in Nature Communications Nat. Commun. 11:3068 (2020)
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.
2020 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 117, 12961-12968 (2020)
Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells.
2020 Nature Communications Nat. Commun. 11:3058 (2020)
Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity (Nature Communications, (2019), 10, 1, (3274), 10.1038/s41467-019-11104-0).
2020 Scientific Article in ChemBioChem ChemBioChem 21, 2495-2502 (2020)
Mapping of the binding interface of PET tracer molecules and Alzheimer Disease Aβ fibrils using MAS solid-state NMR spectroscopy.
2020 Scientific Article in Transplant Immunology Transpl. Immunol. 61:101291 (2020)
Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors.
2020 Review in Hormone and Metabolic Research Horm. Metab. Res. 52, 435-447 (2020)
In situ metabolite mass spectrometry imaging: New insights into the adrenal gland.
2020 Scientific Article in Journal of Virology J. Virol. 94:e00284-20 (2020)
The Epstein-Barr virus major tegument protein BNRF1 is a common target of cytotoxic CD4+ T cells.
2020 Scientific Article in Frontiers in Oncology Front. Oncol. 10:494 (2020)
The intratumoral heterogeneity reflects the intertumoral subtypes of glioblastoma multiforme: A regional immunohistochemistry analysis.
2020 Scientific Article in Molecular Oncology Mol. Oncol. 14, 1653-1669 (2020)
Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100953 (2020)
De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry.
2020 Scientific Article in Cell Reports Cell Rep. 31:107522 (2020)
Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma.
2020 Scientific Article in Gut (eGut) Gut 69, 1939-1951 (2020)
Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn's disease recurrence.
2020 Scientific Article in Clinical and translational immunology Clin. Transl. Immunology 9:e1117 (2020)
Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: Results of a phase I trial.
2020 Review in Seminars in Immunopathology Semin. Immunopathol. 42, 131-142 (2020)
Epigenetic lifestyle of Epstein-Barr virus.
2020 Scientific Article in Journal of the American Geriatrics Society J. Am. Geriatr. Soc. 68, 940-942 (2020)
China's oldest coronavirus survivors.
2020 Scientific Article in Cell Death & Disease Cell Death Dis. 11:192 (2020)
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction.
2020 Scientific Article in Hypertension Hypertension 75, 634-644 (2020)
Mass spectrometry imaging establishes 2 distinct metabolic phenotypes of aldosterone-producing cell clusters in primary aldosteronism.
2020 Scientific Article in Nature Communications Nat. Commun. 11:685 (2020)
A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation.
2020 Scientific Article in Journal of Virology J. Virol. 94:e01918-19 (2020)
Identification and cloning of a new western Epstein-Barr virus strain that replicates efficiently in primary B cells.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100978 (2020)
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:79 (2020)
Mass Spectrometry imaging of atherosclerosis-affine Gadofluorine following Magnetic Resonance imaging.
2020 Scientific Article in Journal of General Virology J. Gen. Virol. 101, 284-289 (2020)
Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-Herpesviruses provides a signature o virus-specific signalling.
2020 Scientific Article in Radiation Oncology Radiat. Oncol. 15:7 (2020)
Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".
2020 Review in Cell and Tissue Research Cell Tissue Res. 380, 341-378 (2020)
Porcine models for studying complications and organ crosstalk in diabetes mellitus.
2020 Scientific Article in Growth Hormone and IGF Research Growth Horm. IGF Res. 51, 6-16 (2020)
Linkage between growth retardation and pituitary cell morphology in a dystrophin-deficient pig model of Duchenne muscular dystrophy.
2020 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 11, 226-240 (2020)
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction.
2020 Scientific Article in Haematologica - The Hematology Journal Haematologica 105, 937-950 (2020)
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.
In: Fundamentals and Applications of Fourier Transform Mass Spectrometry. 2019. 253-279
In situ metabolomics in cancer tissue by high-resolution mass spectrometry imaging.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:19483 (2019)
Dusp8 affects hippocampal size and behavior in mice and humans.
2019 Scientific Article in Journal of Molecular Biology J. Mol. Biol. 431, 4910-4921 (2019)
Biochemical and structural insights into Carbonic Anhydrase XII/Fab6A10 complex.
2019 Scientific Article in Cell Cell 179, 1661-1676 (2019)
Deep learning reveals cancer metastasis and therapeutic antibody targeting in entire body.
2019 Scientific Article in Nature Nature 576, 287-292 (2019)
Patch repair of deep wounds by mobilized fascia.
2019 Scientific Article in Small Small 15:1904112 (2019)
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.
2019 Scientific Article in Nature metabolism Nat. Metab. 1, 1009-1026 (2019)
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 130-130 (2019)
Targets of the T cell response to human herpesvirus 6B.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 99-100 (2019)
The T cell epitope repertoire of polyomavirus BK.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 85-85 (2019)
B-Raf and Raf-1 are dispensable for activation of the MAPK/Erk signaling pathway in murine B cells but contribute to plasma cell differentiation.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 112-112 (2019)
The antigen-specific T-cell receptor repertoire against human cytomegalovirus.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 25-26 (2019)
"Two B or not two B?" The potency of Nntch2 in follicular vs marginal zone B cell identity.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 69-70 (2019)
Type-I interferon regulates ghrelin-levels leading to anorexia and weight loss while promoting inflammatory immune responses.
2019 Meeting abstract in Bone Marrow Transplantation Bone Marrow Transplant. 54, 177-178 (2019)
Single cell identification of defined ebv epitope-specific TCR alpha beta pairs for adoptive T cell transfer against EBV infection and EBV-associated malignancies.
2019 Scientific Article in Pathogens Pathogens 8:177 (2019)
Proliferative kidney disease and proliferative darkening syndrome are linked with brown trout (Salmo trutta fario) mortalities in the pre-alpine Isar River.
2019 Scientific Article in mBio mBio 10:e01723-19 (2019)
First days in the life of naïve human B-lymphocytes infected with Epstein-Barr Virus.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0221454 (2019)
Beam size limit for pencil minibeam radiotherapy determined from side effects in an in-vivo mouse ear model.
2019 Scientific Article in Journal of Cell Science J. Cell Sci. 132:jcs223891 (2019)
Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.
2019 Scientific Article in JCI insight JCI insight 4:e130356 (2019)
In situ metabolomics of aldosterone-producing adenomas.
2019 Scientific Article in Clinical Chemistry Clin. Chem. 65, 1276-1286 (2019)
Prognostic relevance of steroid sulfation in adrenocortical carcinoma revealed by molecular phenotyping using high resolution mass spectrometry imaging.
2019 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 17:89 (2019)
Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma.
2019 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 10:487 (2019)
Heat shock protein 90 as a prognostic marker and therapeutic target for adrenocortical carcinoma.
2019 mBio mBio 10:e01482-19 (2019)
MicroRNAs of Epstein-Barr Virus attenuate T-cell-mediated immune control in vivo (vol 10, e01941-18, 2019).
2019 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 116, 16046-16055 (2019)
Epstein-Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection.
2019 Scientific Article in Nature Communications Nat. Commun. 10:3274 (2019)
Involvement of G-quadruplex regions in mammalian replication origin activity.
2019 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 12:dmm039156 (2019)
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:9925 (2019)
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.
2019 Meeting abstract in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 32, A12-A12 (2019)
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.
2019 Scientific Article in ACS Nano ACS Nano 13, 8114-8123 (2019)
Iron-sequestering nanocompartments as multiplexed Electron Microscopy gene reporters.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:8492 (2019)
Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S24-S25 (2019)
A 16q24.3 4-gene mRNA signature predicts outcome in radio(chemo)therapy-treated head and neck squamous cell carcinoma.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S25-S25 (2019)
A five-microRNA-signature predicts recurrence and survival in HPV-negative HNSCC.
2019 Scientific Article in Veterinary Medicine Austria Wien. Tierärztl. Mschr. 106, 109-115 (2019)
Autochthonous Taenia crassiceps infection in a ring-tailed lemur (Lemur catta) in the Salzburg Zoo.
2019 Scientific Article in Laboratory Investigation Lab. Invest. 99, 1535-1546 (2019)
Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis.
2019 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 216, 1700-1723 (2019)
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 26, 30-44 (2019)
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.
2019 Scientific Article in Cancers Cancers 11:727 (2019)
Acute skin damage and late radiation-induced fibrosis and inflammation in murine ears after high-dose irradiation.
2019 Scientific Article in Cancers Cancers 11:594 (2019)
Impact of extrinsic and intrinsic hypoxia on catecholamine biosynthesis in absence or presence of Hif2 alpha in pheochromocytoma cells.
2019 Scientific Article in Life Science Alliance Life Sci. All. 2:e201800108 (2019)
BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.
2019 Meeting abstract in Molecular Therapy Mol. Ther. 27, 175-176 (2019)
Cord blood derived CAR-T cells targeting gp350 containing CD28/CD3 zeta or 4-1BB/CD3 zeta signaling domains directly react against cells infected with EBV bypassing the need of HLA-matched memory T cells.
2019 Review in Acta neurochirurgica Acta Neurochir. 161, 1109-1124 (2019)
Intracavitary radioimmunotherapy of high-grade gliomas: Present status and future developments.
2019 Scientific Article in Blood Blood 133, 2597-2609 (2019)
Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
2019 Scientific Article in Nature Communications Nat. Commun. 10:1415 (2019)
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.
2019 Scientific Article in Diabetes Diabetes 68, 1329-1340 (2019)
Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway.
2019 Scientific Article in Nature Communications Nat. Commun. 10:1114 (2019)
Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging.
2019 Review in Frontiers in Oncology Front. Oncol. 9:104 (2019)
Progress in EBV vaccines.
2019 Review in Histochemistry and Cell Biology Histochem. Cell Biol. 151, 201-216 (2019)
Novel methods in adrenal research: A metabolomics approach.
2019 Scientific Article in Journal of extracellular vesicles J. Extra. Vesicles 8:1573051 (2019)
Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL.
2019 Scientific Article in PLoS Biology PLoS Biol. 17:e2006767 (2019)
The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0210998 (2019)
Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis.
2019 Scientific Article in Cell Metabolism Cell Metab. 29, 932-949.e4 (2019)
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits.
2019 Scientific Article in Cellular & Molecular Immunology Cell. Mol. Immunol. 16, 412-414 (2019)
Reproducing indolent B-cell lymphoma transformation with T-cell immunosuppression in LMP1/CD40-expressing mice.
2019 Scientific Article in mBio mBio 10:01941-18 (2019)
MicroRNAs of Epstein-Barr Virus attenuate T-cell-mediated immune control in vivo.
2019 Scientific Article in American Journal of Pathology, The Am. J. Pathol. 189, 521-539 (2019)
Spatiotemporally skewed activation of PD-1 T cells after epstein barr virus infection and tumor development in long-term fully humanized mice.
2019 Scientific Article in Proteomics - Clinical Applications Proteomics Clin. Appl. 13:e1800137 (2019)
Integrative clustering in mass spectrometry imaging for enhanced patient stratification.
2019 Scientific Article in ACS Nano ACS Nano 13, 1029-1041 (2019)
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.
2019 Scientific Article in European Journal of Immunology Eur. J. Immunol. 49, 351-352 (2019)
B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?
2019 Scientific Article in Gastroenterology Gastroenterology 156, 203-217.e20 (2019)
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.
2019 Scientific Article in International Journal of Obesity Int. J. Obes. 43, 1305-1318 (2019)
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.
2019 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 25, 1505-1516 (2019)
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV-infection.
2018 Meeting abstract in Blood Blood 132 (2018)
Pembrolizumab therapy exacerbates EBV-induced infections and tumors in a long-term fully humanized mouse model.
2018 Meeting abstract in Blood Blood 132 (2018)
The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells.
2018 Meeting abstract in Blood Blood 132 (2018)
PARP14 is a novel therapeutic target in STAT6 mutant follicular lymphoma.
2018 Meeting abstract in Blood Blood 132 (2018)
CAR-T cells targeting gp350 recognize immortalized cells latently infected with EBV.
2018 Scientific Article in Journal of Virology J. Virol. 93:e01618-18 (2018)
Epstein-Barr virus induces expression of the LPAM-1 integrin in B cells in vitro and in vivo.
2018 Meeting abstract in European Respiratory Journal Eur. Respir. J. 52 (2018)
Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging.
2018Poster: International Conference on EBV & KSHV 2018, 28 July - 01 August 2018, Madison. (2018)
Structure and function of the EBNA2/PLK1 protein complex.
2018 Scientific Article in PLoS Pathogens PLoS Pathog. 14:e1007464 (2018)
Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.
2018 Scientific Article in Journal of Immunology J. Immunol. 202, 979-990 (2018)
Antigen-specific TCR signatures of cytomegalovirus infection.
2018 Scientific Article in Journal of extracellular vesicles J. Extra. Vesicles 7, 1535750 (2018)
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): A position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
2018 Nature Communications Nat. Commun. 9:4975 (2018)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018).
2018 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 197 (2018)
Pharmacometabolic response to pirfenidone treatment in pulmonary fibrosis detected by high resolution MALDI FTICR-mass spectrometry imaging.
2018 Scientific Article in Nature Communications Nat. Commun. 9:4304 (2018)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
2018 Scientific Article in Nature Communications Nat. Commun. 9:3839 (2018)
Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia.
2018 Scientific Article in Molecular Oncology Mol. Oncol., DOI: 10.1002/1878-0261.12388 (2018)
A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC).
2018 Scientific Article in PLoS Biology PLoS Biol. 16:e2005233 (2018)
Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.
2018 Scientific Article in Molecular Metabolism Mol. Metab., DOI: 10.1016/j.molmet.2018.07.002 (2018)
Chronic d-serine supplementation impairs insulin secretion.
2018 Meeting abstract in Cancer Research Cancer Res. 78, 61-62 (2018)
Metabolic signature in lethal vs. nonlethal prostate cancer.
2018 Scientific Article in Biochemical and Biophysical Research Communications Biochem. Biophys. Res. Commun. 503, 2770-2777 (2018)
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
2018 Scientific Article in Science Science 361:eaar7191 (2018)
Shifting the limits in wheat research and breeding using a fully annotated reference genome.
2018 Scientific Article in European Respiratory Journal Eur. Respir. J. 52:1702314 (2018)
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.
2018 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 127, E581-E582 (2018)
Detection of radiation induced lung fibrosis using x-ray dark-field imaging in a murine model.
2018 Scientific Article in Vaccine Vaccine 36, 5124-5132 (2018)
Immunization with a recombinant fusion protein protects mice against Helicobacter pylori infection.
2018 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 198, 1527-1538 (2018)
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.
2018 Scientific Article in Immunity Immunity 49, 120-133.e9 (2018)
LAG-3 inhibitory receptor expression identifies immunosuppressive natural regulatory plasma cells.
2018 Scientific Article in OncoTarget Oncotarget 9, 26800-26816 (2018)
Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
2018 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 410, 5969–5980 (2018)
Round robin study of formalin-fixed paraffin-embedded tissues in mass spectrometry imaging.
2018 Scientific Article in Radiation Oncology Radiat. Oncol. 13:123 (2018)
Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".
2018 Scientific Article in Leukemia Leukemia 33, 88-98 (2018)
Antibodies conjugated with viral antigens elicit a cytotoxic T cell response against primary CLL ex vivo.
2018 Scientific Article in Leukemia Leukemia 33, 132–147 (2018)
Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas.
2018 Scientific Article in BMC Evolutionary Biology BMC Evol. Biol. 18:96 (2018)
Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution.
2018 Scientific Article in ChemMedChem ChemMedChem 13, 1230-1237 (2018)
Fully automated production and characterization of 64Cu and proof-of-principle small-animal PET imaging using 64Cu-labelled CA XII targeting 6A10 fab.
2018 Scientific Article in Neural regeneration research Neural Regen. Res. 13, 854-861 (2018)
Validation of a novel animal model for sciatic nerve repair with an adipose-derived stem cell loaded fibrin conduit.
2018 Scientific Article in Heliyon Heliyon 4:e00606 (2018)
Molecular imaging of myocardial infarction with Gadofluorine P – A combined magnetic resonance and mass spectrometry imaging approach.
2018 Scientific Article in Journal of Translational Medicine J. Transl. Med. 16:124 (2018)
Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts.
2018 Scientific Article in International Journal of Cancer Int. J. Cancer 143, 2065-2075 (2018)
An inhibitory antibody targeting carbonic anhydrase XII abrogates chemoresistance and significantly reduces lung metastases in an orthotopic breast cancer model in vivo.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0193554 (2018)
Characterization and clinical enrichment of HLA-C*07:02-restricted Cytomegalovirus-specific CD8+ T cells.
2018 Scientific Article in Chemical Communications Chem. Commun. 54, 5426-5429 (2018)
hIAPP forms toxic oligomers in plasma.
2018 Scientific Article in Cancer Medicine Cancer Med. 7, 2013-2020 (2018)
Tumor-derived extracellular vesicles activate primary monocytes.
2018 Scientific Article in PLoS Pathogens PLoS Pathog. 14:e1006991 (2018)
Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B.
2018 Scientific Article in International Journal of Cancer Int. J. Cancer 143, 1505-1515 (2018)
A genomic copy number signature predicts radiation exposure in post-Chernobyl breast cancer.
2018 Scientific Article in Nuclear Medicine and Biology Nucl. Med. Biol. 60, 55-62 (2018)
Evaluation of 177Lu[Lu]-CHX-A″-DTPA-6A10 Fab as a radioimmunotherapy agent targeting carbonic anhydrase XII.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:1801 (2018)
Spatiotemporal patterning of EpCAM is important for murine embryonic endo-And mesodermal differentiation.
2018 Scientific Article in Cell Reports Cell Rep. 22, 992-1002 (2018)
Notch2 signaling maintains NSC quiescence in the murine ventricular-subventricular zone.
2018 Scientific Article in Molecular Immunology Mol. Immunol. 94, 176-182 (2018)
Immunization with recombinant FliD confers protection against Helicobacter pylori infection in mice.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:1116 (2018)
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
2018 Scientific Article in Endocrinology Endocrinology 159, 1511-1524 (2018)
High resolution tissue mass spectrometry imaging reveals a refined functional anatomy of the human adult adrenal gland.
2018 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 67, 663-674 (2018)
Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.
2018 Scientific Article in Radiation and Environmental Biophysics Radiat. Environ. Biophys. 57, 99-113 (2018)
Lifetime study in mice after acute low-dose ionizing radiation: A multifactorial study with special focus on cataract risk.
2018 Scientific Article in International Journal of Oncology Int. J. Oncol. 52, 755-767 (2018)
PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients.
2018 Scientific Article in Cell Cell 172, 409–422.e21 (2018)
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.
2018 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 25, 145-162 (2018)
Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: A novel model of invasive medullary thyroid carcinoma.
2018 Scientific Article in Laboratory Investigation Lab. Invest. 98, 141-149 (2018)
Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model: MALDI imaging mass spectrometry in comparative medicine.
2018 Scientific Article in International Journal of Cancer Int. J. Cancer 142, 573-583 (2018)
Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer.
2017 Scientific Article in Plant Journal, The Plant J. 93, 502-514 (2017)
The pseudogenes of barley.
2017 Meeting abstract in Free Radical Biology and Medicine Free Radical Biol. Med. 112, 24-24 (2017)
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.
2017 Scientific Article in Science Science 358:eaan4368 (2017)
The target landscape of clinical kinase drugs.
2017 Scientific Article in eLife eLife 6:e31226 (2017)
Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate.
2017 Scientific Article in Rapid Communications in Mass Spectrometry Rapid Commun. Mass Spectrom. 32, 159-166 (2017)
Correlative mass spectrometry imaging, applying TOF-SIMS and AP-MALDI to a single tissue section.
2017 Scientific Article in OncoTarget Oncotarget 8, 78917-78929 (2017)
Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma.
2017 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 40, 239-239 (2017)
Adoptive transfer of CMV- and EBV-specific peptide-stimulated T cells after allogeneic stem cell transplantation: First results of a phase I/IIa clinical trial [AIT-MULTIVIR-01].
2017 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 40, 20-20 (2017)
CK2 inhibition reduces cell proliferation in acute B-lymphoblastic leukemia cells in vitro and in vivo.
2017 Scientific Article in Biochimica et Biophysica Acta Biochim. Biophys. Acta 1862, 51-60 (2017)
PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI.
2017 Scientific Article in FASEB Journal FASEB J. 32, 703-716 (2017)
Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis.
2017 Scientific Article in PLoS Pathogens PLoS Pathog. 13, e1006664:e1006664 (2017)
EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.
2017 Scientific Article in Journal of Pathology, The J. Pathol. 243, 481-495 (2017)
A new model system identifies EGFR/HER2 and HER2/HER3 heterodimers as potent inducers of oesophageal epithelial cell invasion.
2017 Scientific Article in Vaccine Vaccine 35, 5131-5139 (2017)
A synthetic human cytomegalovirus pp65-IE1 fusion antigen efficiently induces and expands virus specific T cells.
2017 Scientific Article in Journal of General Virology J. Gen. Virol. 98, 2128-2142 (2017)
Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.
2017 Scientific Article in Proceedings of SPIE Proc. SPIE 10411:104110F (2017)
Fluorescently labeled bevacizumab in human breast cancer: Defining the classification threshold.
2017 Scientific Article in EMBO Journal, The EMBO J. 36, 2726-2741 (2017)
Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.
2017 Scientific Article in American Journal of Pathology, The Am. J. Pathol. 187, 2570-2589 (2017)
Deletion of endothelial TGF-β signaling leads to choroidal neovascularization.
2017 Scientific Article in Biological Chemistry Biol. Chem. 398, 1151-1164 (2017)
Tissue kallikrein-related peptidase 4 (KLK4), a novel biomarker in triple-negative breast cancer.
2017 Scientific Article in OncoTarget Oncotarget 8, 68012-68025 (2017)
Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome.
2017 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 40, 135-135 (2017)
Induction of antigen-specific T-cell responses through dendritic cell vaccination in AML: Results of a phase I/II trial and ex vivo enhancement by checkpoint blockade.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0179124 (2017)
Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray.
2017 Scientific Article in Journal of Virology J. Virol. 91:e01667-16 (2017)
MicroRNAs of Epstein-Barr virus control innate and adaptive anti-viral immunity.
2017 Meeting abstract in Haematologica - The Hematology Journal Haematologica 102, 656-657 (2017)
Adult primary acute leukemia samples with chromosomal translocations grow well in immunodeficient mice, but are difficult to transduce with lentiviruses.
2017 Meeting abstract in Haematologica - The Hematology Journal Haematologica 102, 333-333 (2017)
Lack of the ferroptosis inhibitor GPX4 in erythroid cells causes a block in reticulocyte maturation and a hypoxic signature with impaired hepcidin regulation.
2017 Scientific Article in Nature Communications Nat. Commun. 8:15126 (2017)
Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid.
2017 Scientific Article in Journal of Trace Elements in Medicine and Biology J. Trace Elem. Med. Biol. 44, 71-75 (2017)
Investigating the influence of standard staining procedures on the copper distribution and concentration in Wilson's disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry.
2017 Scientific Article in Haematologica - The Hematology Journal Haematologica 102, 883-894 (2017)
c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Wnt5a is secreted by extracellular vesicles in pulmonary fibrosis and increases fibroblasts proliferation.
2017 Scientific Article in Cell Metabolism Cell Metab. 25, 1334-1347.e4 (2017)
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.
2017 Scientific Article in Nature Communications Nat. Commun. 8:14715 (2017)
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis.
2017 Scientific Article in RNA Biology RNA Biol. 14, 1-10 (2017)
Antibodies specific for nucleic acid modifications.
2017 Scientific Article in JCI insight JCI insight 2:93136 (2017)
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S75-S75 (2017)
Clones with and without sensitivity towards treatment in vivo co-exist within a single sample of a patient with ALL.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S74-S75 (2017)
XIAP is an attractive therapeutic target for all as validated in innovative genetically rngineered patient-derived xenograft models.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S73-S73 (2017)
Targeting the ER-mitochondrial interface of cell death sensitizes leukemia cells towards cytostatics.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S68-S68 (2017)
Modeling AML standard induction chemotherapy in the PDX mouse model.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S71-S72 (2017)
Primary adult acute lymphoblastic leukemic cells reliably engraft and grow in immunodeficient mice.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S74-S74 (2017)
A preclinical PDX model for patients` minimal residual disease in ALL.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S52-S52 (2017)
A rare population of drug resistant, dormant stem cells exists in patients' acute lymphoblastic leukemia growing in mice.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S59-S59 (2017)
Transcriptional heterogeneity in AML - evolution of gene expression in patient derived xenografts.
2017 Meeting abstract in Annals of Hematology Ann. Hematol. 96, S57-S57 (2017)
Detection of single-nucleotide variants in acute myeloid leukemia (AML) from bulk and single-cell RNA sequencing.
2017 Review in Nature Methods Nat. Methods 14, 228-232 (2017)
EV-TRACK: Transparent reporting and centralizing knowledge in extracellular vesicle research.
2017 Scientific Article in American Journal of Respiratory Cell and Molecular Biology Am. J. Respir. Cell Mol. Biol. 57, 77-90 (2017)
A novel antifibrotic mechanism of nintedanib and pirfenidone: Inhibition of collagen fibril assembly.
2017 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 66, 777-786 (2017)
Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: Comparison between primary tumors and metastases.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0172788 (2017)
Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:44041 (2017)
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.
2017 Scientific Article in Nature Communications Nat. Commun. 8:14209 (2017)
A human immunodeficiency syndrome caused by mutations in CARMIL2.
2017 Scientific Article in Nature Communications Nat. Commun. 8:14257 (2017)
Epstein-Barr virus particles induce centrosome amplification and chromosomal instability.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 256-266 (2017)
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.
2017 Scientific Article in Haematologica - The Hematology Journal Haematologica 102, e69-e72 (2017)
Human RAD52: a novel player in DNA repair in cancer and immunodeficiency.
2017 Scientific Article in Advances in Cancer Research Adv. Cancer Res. 134, 117-132 (2017)
In situ metabolomics in cancer by mass spectrometry imaging.
2017 Scientific Article in Nature medicine Nat. Med. 23, 69-78 (2017)
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.
2017 Scientific Article in Neoplasia : An International Journal for Oncology Research Neoplasia 19, 8-16 (2017)
Integrin-targeted hybrid fluorescence molecular tomography/X-ray computed tomography for imaging tumor progression and early response in non-small cell lung cancer.
2017 Scientific Article in Biological Chemistry Biol. Chem. 398, 765-773 (2017)
Plasmin(Ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer.
2017 Scientific Article in Cancer Research Cancer Res. 77, 623-631 (2017)
Threshold analysis and biodistribution of fluorescently labeled bevacizumab in human breast cancer.
2017 Scientific Article in Nature Chemical Biology Nat. Chem. Biol. 13, 91-98 (2017)
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
2016 Scientific Article in Cancer Cell Cancer Cell 30, 849-862 (2016)
Characterization of rare, dormant, and therapy-resistant cells in acute lymphoblastic leukemia.
2016 Meeting abstract in European Journal of Cancer Eur. J. Cancer 68, S135-S135 (2016)
Identification of predictive response and resistance factors to targeted therapy in gastric cancer using a systems medicine approach.
2016 Meeting abstract in European Journal of Cancer Eur. J. Cancer 68, S58-S59 (2016)
X-Linked inhibitor of apoptosis protein (XIAP) exhibits an essential role of patients' acute lymphoblastic leukemia cells growing in vivo.
2016 Scientific Article in Blood Blood 128, 2517-2526 (2016)
HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma.
2016 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 39, 214-214 (2016)
CXCR4-directed peptide receptor radiotherapy with 177Lu-Pentixather effectively clears leukemia in patient-derived xenografts.
2016 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 39, 135-135 (2016)
Induction of antigen-specific T-cell responses through dendritic cell vaccination in AML: results of a phase I/II trial and ex vivo enhancement by checkpoint blockade.
2016 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, 12244-12249 (2016)
Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data.
2016 Scientific Article in Brain and behavior Brain Behav. 6:e00578 (2016)
Sensory reanimation of the hand by transfer of the superficial branch of the radial nerve to the median and ulnar nerve.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0164298 (2016)
Sphingomyelin synthase 1 is essential for male fertility in mice.
2016 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, E6467-E6475 (2016)
Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
2016 Meeting abstract in Experimental Hematology Exp. Hematol. 44, S94-S94 (2016)
A rare subpopulation of dormant, drug resistant stem cells in all mimics cells of minimal residual disease.
2016 Meeting abstract in Experimental Hematology Exp. Hematol. 44, S105-S105 (2016)
Novel genetically engineered patient-derived xenograft (GEPDX) models reveal that xiap plays an essential role for patients´all growing in mice.
2016 Review in Histochemistry and Cell Biology Histochem. Cell Biol. 146, 1-26 (2016)
Deep tissue imaging: A review from a preclinical cancer research perspective.
2016 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 213, 2065-2080 (2016)
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.
2016 Meeting abstract in Haematologica - The Hematology Journal Haematologica 101, 1, 574-574 (2016)
The immune surveillance constraints B Cell lymphomas with continuous CD40 signaling to an indolent phenotype.
2016 Scientific Article in BMC Cancer BMC Cancer 16:615 (2016)
uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.
2016 Scientific Article in Nature Communications Nat. Commun. 7:12597 (2016)
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.
2016 Scientific Article in Blood Blood 128, 2435-2449 (2016)
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice.
2016 Scientific Article in Neoplasia : An International Journal for Oncology Research Neoplasia 18, 459-467 (2016)
High-resolution multispectral optoacoustic tomography of the vascularization and constitutive hypoxemia of cancerous tumors.
2016 Scientific Article in Journal of Clinical Immunology J. Clin. Immunol. 36, 684-692 (2016)
Fatal lymphoproliferative disease in two siblings lacking functional FAAP24.
2016 Scientific Article in Nature Protocols Nat. Protoc. 11, 1428-1443 (2016)
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue.
2016 Scientific Article in Journal of Nuclear Medicine J. Nucl. Med. 57, 1971-1977 (2016)
Tumor uptake of anti-CD20 Fabs depends on tumor perfusion.
2016 Scientific Article in Journal of Clinical Virology J. Clin. Virol. 82, 33-40 (2016)
Occurrence, risk factors and outcome of adenovirus infection in adult recipients of allogeneic hematopoietic stem cell transplantation.
2016 Scientific Article in Nature Nature 535, 430-434 (2016)
Identification of proliferative and mature β-cells in the islets of Langerhans.
2016 Scientific Article in Cancer Research Cancer Res. 76, 4113-4123 (2016)
Immuno-PET imaging of engineered human T cells in tumors.
2016 Scientific Article in OncoTarget Oncotarget 7, 44062-44075 (2016)
Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer.
2016 Scientific Article in Diabetes Diabetes 65, 2540-2552 (2016)
Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice.
2016 Scientific Article in Cell Reports Cell Rep. 15, 2331-2339 (2016)
CEACAM1-mediated inhibition of virus production.
2016 Meeting abstract in Cancer Immunology Research Cancer Immunol. Res. 4:B070 (2016)
Characterization of covariables modulating CD33/CD3 BITE antibody construct mediated cytotoxicity against primary AML cells.
2016 Meeting abstract in Cancer Immunology Research Cancer Immunol. Res. 4:B146 (2016)
Next-generation dendritic cell vaccination in postremission therapy of AML: Results of a clinical phase I trial.
2016 Scientific Article in Analytical Chemistry Anal. Chem. 88, 5871-5878 (2016)
Spatial autocorrelation in mass spectrometry imaging.
2016 Scientific Article in Small Small 12, 3245-3257 (2016)
Multiphoton microscopy of nonfluorescent nanoparticles in vitro and in vivo.
2016 Scientific Article in Analytical Chemistry Anal. Chem. 88, 5281-5289 (2016)
How suitable is MALDI-TOF for metabolite imaging from clinical formalin-fixed and paraffin-embedded tissue samples in comparison to MALDI-FT-ICR mass spectrometry?
2016 Scientific Article in American Journal of Cancer Research Am. J. Cancer Res. 6, 61-70 (2016)
Assessment of kallikrein-related peptidase 5 (KLK5) protein expression in tumor tissue of advanced ovarian cancer patients by immunohistochemistry and ELISA: Correlation with clinical outcome.
2016 Scientific Article in Cancer Cell Cancer Cell 29, 574-586 (2016)
The public repository of xenografts enables discovery and randomized phase II-like trials in mice.
2016 Scientific Article in Journal of Biomolecular Screening J. Biomol. Screen. 21, 596-607 (2016)
Identification of small-molecule frequent hitters of glutathione S-transferase-glutathione interaction.
2016 Scientific Article in Journal of Trace Elements in Medicine and Biology J. Trace Elem. Med. Biol. 35, 97-102 (2016)
Element bioimaging of liver needle biopsy specimens from patients with Wilson's disease by laser ablation-inductively coupled plasma-mass spectrometry.
2016 Scientific Article in PLoS Pathogens PLoS Pathog. 12:e1005510 (2016)
Multiple lytic origins of replication are required for optimal gammaherpesvirus fitness in vitro and in vivo.
2016 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 39, 76-77 (2016)
Identification of metabolic changes in pancreatic ductal adenocarcinoma.
2016 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 39, 16-17 (2016)
Clinical validation of response and resistance factor candidates to targeted therapy in Gastric Cancer (GC).
2016 Scientific Article in Metallomics Metallomics 8, 648-653 (2016)
Elemental bioimaging and speciation analysis for the investigation of Wilson's disease using μXRF and XANES.
2016 Meeting abstract in Modern Pathology Mod. Pathol. 29, 170A (2016)
Low frequency of epithelial PD-L1 staining in esophageal and other gastrointestinal adenocarcinomas.
2016 Meeting abstract in Modern Pathology Mod. Pathol. 29, 53A (2016)
Intratumoral heterogeneity of common protein biomarkers assessed by immunohistochemistry in breast cancer tissues.
2016 Scientific Article in Journal of Proteome Research J. Proteome Res. 15, 1350-1359 (2016)
Proteomic profiling suggests central role of STAT signaling during retinal degeneration in the rd10 mouse model.
2016 Meeting abstract in Laboratory Investigation Lab. Invest. 96, 170A (2016)
Low frequency of epithelial PD-L1 staining in esophageal and other gastrointestinal adenocarcinomas.
2016 Meeting abstract in Laboratory Investigation Lab. Invest. 96, 53A (2016)
Intratumoral heterogeneity of common protein biomarkers assessed by immunohistochemistry in breast cancer tissues.
2016 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 44, 4636-4650 (2016)
RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.
2016 Scientific Article in Molecular Cancer Therapeutics Mol. Cancer Ther. 15, 1145-1152 (2016)
Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancer.
2016 Scientific Article in Expert Review of Proteomics Expert Rev. Proteomics 13, 275-284 (2016)
MALDI imaging mass spectrometry as a novel tool for detecting histone modifications in clinical tissue samples.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0146281 (2016)
Murine embryonic stem cell plasticity is regulated through klf5 and maintained by metalloproteinase mmp1 and hypoxia.
2016 Scientific Article in PLoS Pathogens PLoS Pathog. 12:e1005383 (2016)
EBNA3C directs recruitment of RBPJ (CBF1) to chromatin during the process of gene repression in EBV infected B cells.
2016 Scientific Article in International Journal of Radiation Oncology, Biology, Physics Int. J. Radiat. Oncol. Biol. Phys. 95, 234-241 (2016)
Proton minibeam radiation therapy reduces side effects in an in vivo mouse ear model.
2016 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 145, 201-211 (2016)
Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging.
2016 Scientific Article in Leukemia Leukemia 30, 1166-1176 (2016)
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
2016 Scientific Article in Proteomics Proteomics 16, 437-447 (2016)
In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry.
2016 Scientific Article in Leukemia Leukemia 30, 484-491 (2016)
Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3-BiTE antibody construct AMG 330: Reversing a T-cell induced immune escape mechanism.
2016 Scientific Article in Multiple Sclerosis Journal Mult. Scler. J. 22, 279-291 (2016)
Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins.
2015 Scientific Article in OncoTarget Oncotarget 6, 43508-43528 (2015)
Anti-leukemic effects of the V-ATPase inhibitor Archazolid A.
2015 Scientific Article in Cell Reports Cell Rep. 13, 2715-2727 (2015)
MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2015, 172 S.
Untersuchungen zur Rolle der Rezeptortyrosinkinasen FLT3, DDR1 und DDR2 in der akuten myeloischen Leukämie.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2015, 144 S.
Notch2 signalling in B cell activation, immune response and lymphomagenesis.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2015, 142 S.
Chromatin remodeling in Epstein-Barr virus after induction of the lytic phase: Molecular characterization of the role of BZLF1 and its interactions.
2015 Meeting abstract in Journal of Clinical Oncology - JCO J. Clin. Oncol. 33:150 (2015)
uPA receptor and its interaction partners: Impact as potential therapeutic targets in triple-negative breast cancer.
2015 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 191:A4409 (2015)
In-situ detection of pirfenidone and endogenous metabolites by maldi-imaging mass spectrometry in fibrotic tissue.
2015 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 191:A2886 (2015)
Impaired immunoproteasome function in COPD.
2015 Meeting abstract in Blood Blood 126 (2015)
Tyrosin kinase inhibition restores the membrane localization of FLT3-ITD.
2015 Meeting abstract in Blood Blood 126 (2015)
Azacitidine in combination with the selective FLT3 kinase inhibitor crenolanib effectively disrupts stromal protection of CD34+Leukemia-Initiating Cells (LIC) in FLT3-ITD+ Acute Myeloid Leukemia (AML).
2015 Meeting abstract in Blood Blood 126:2630 (2015)
Single cell RNA sequencing reveals increased adhesion signals in treatment-resistant tumor stem cells in a preclinical mouse model of genetically engineered patient-derived acute lymphoblastic leukemia.
2015 Meeting abstract in Blood Blood 126:3062 (2015)
Functional diversity of single stem cell clones in patients' acute lymphoblastic leukemia growing in mice: An adverse subclone with distinct DNA-methylation pattern, slow growth in vivo and drug resistance.
2015 Meeting abstract in Blood Blood 126:3252 (2015)
Proxe: A public repository of xenografts to facilitate studies of biology and expedite preclinical drug development in leukemia and lymphoma.
2015 Meeting abstract in Blood Blood 126:2632 (2015)
The novel technique of Genetically Engineered Patient-Derived Xenografts (GEPDX) reveals that the X-linked Inhibitor of Apoptosis Protein (XIAP) plays an essential role for maintenance and growth of patients' acute lymphoblastic leukemia in vivo.
2015 Meeting abstract in Blood Blood 126:3805 (2015)
Next-generation dendritic cell vaccination in postremission therapy of AML: Results of a clinical phase I trial.
2015 Meeting abstract in Annals of Hematology Ann. Hematol. 94, S88 (2015)
Knockdown of XIAP sensitizes B-ALL cells towards chemotherapy in an innovative, dual luciferase in vivo competition assay.
2015 Meeting abstract in Annals of Hematology Ann. Hematol. 94, S83-S84 (2015)
In vivo imaging facilitates reliable and sensitive monitoring of preclinical in vivo treatment trials in the individualized xenograft mouse model of AML.
2015 Meeting abstract in Annals of Hematology Ann. Hematol. 94, S28-S30 (2015)
Functional characterization ofacute leukemias.
2015 Meeting abstract in Annals of Hematology Ann. Hematol. 94, S89 (2015)
Single cell clones from a patient with all show different drug sensitivity and growth behavior in vivo.
2015 Meeting abstract in Annals of Hematology Ann. Hematol. 94, S88-S89 (2015)
Drug sensitivity of patient-derived ALL tumor cells is impaired by co-culture with feeder cells mimicking the in vivo micro-environment.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0145678 (2015)
Prevention of tumor formation by latent gammaherpesvirus infection.
2015 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 38, 37 (2015)
Next-generation dendritic cell vaccination in postremission therapy of AML: Results of a clinical phase I trial.
2015 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 38, 38 (2015)
Combining immune checkpoint inhibition with the CD33 BiTE (R) antibody construct AMG 330 to enhance T cell mediated lysis of primary AML cells.
2015 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 38, 99 (2015)
Very early functional in-vivo imaging to predict response to B cell receptor pathway targeting in lymphoma.
2015 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 38, 214 (2015)
The combination of crenolanib and azacitidine effectively targets leukemia-initiating cells in FLT3-ITD+ AML to overcome protection by the bone marrow niche.
2015 Scientific Article in Frontiers in Immunology Front. Immunol. 6:598 (2015)
A diverse repertoire of CD4 T cells targets the immediate-early 1 protein of human cytomegalovirus.
2015 Scientific Article in Current Opinion in Virology Curr. Opin. Virol. 14, 138-144 (2015)
Epstein-Barr virus latency: Current and future perspectives.
2015 Meeting abstract in Haematologica - The Hematology Journal Haematologica 100, 201 (2015)
A rare subpopulation of quiescent, drug resistant stem cells in patients' all cells growing in mice.
2015 Meeting abstract in Haematologica - The Hematology Journal Haematologica 100, 201 (2015)
Patient's single stem cell clones of acute lymphoblastic leukemia show drug resistance and slow proliferation in mice in vivo.
2015 Meeting abstract in Haematologica - The Hematology Journal Haematologica 100, 287 (2015)
Dendritic cell vaccination in postremission therapy of aml: Results of a clinical phase i trial and of preclinical studies testing combinatorial approaches.
2015 Meeting abstract in Haematologica - The Hematology Journal Haematologica 100, 200 (2015)
XIAP exhibits an essential role for patients' all cells growing in vivo as shown by a novel technique for stable knockdown in Patient-Derived Xenograft (PDX) all cells.
2015 Scientific Article in Current Topics in Microbiology and Immunology Curr. Top. Microbiol. Immunol. 390, 103-117 (2015)
The epigenetic life cycle of epstein–barr virus.
2015 Scientific Article in Vaccine Vaccine 33, 5532-5538 (2015)
Simultaneous immunization of mice with Omp31 and TF provides protection against Brucella melitensis infection.
2015 Scientific Article in Current Topics in Microbiology and Immunology Curr. Top. Microbiol. Immunol. 391, 119-149 (2015)
The Latent Membrane Protein 1 (LMP1).
2015 Scientific Article in Current Topics in Microbiology and Immunology Curr. Top. Microbiol. Immunol. 391, 35-39 (2015)
EBNA2 and its coactivator EBNA-LP.
2015 Scientific Article in Biomedical Optics Express Biomed. Opt. Express 6, 3134-3148 (2015)
Optical mesoscopy without the scatter: Broadband multispectral optoacoustic mesoscopy.
2015 Scientific Article in Cell Metabolism Cell Metab. 22, 838-850 (2015)
Calcineurin links mitochondrial elongation with energy metabolism.
2015 Scientific Article in Diabetes Diabetes 64, 4099-4111 (2015)
Notch1 and Notch2 in podocytes play differential roles during diabetic nephropathy development.
2015 Scientific Article in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 192, 1089-1101 (2015)
Regulation of 26S proteasome activity in pulmonary fibrosis.
2015 Scientific Article in Journal of the American Heart Association J. Am. Heart Assoc. 4:e002153 (2015)
Heart-specific knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction in the aging myocardium.
2015 Scientific Article in Leukemia Leukemia 29, 2307-2316 (2015)
Effects of p38α/β inhibition on Acute Lymphoblastic Leukemia (ALL) proliferation and survival in vivo.
2015 Scientific Article in Annals of Hematology Ann. Hematol. 94, 1677-1688 (2015)
Virus infection in HLA-haploidentical hematopoietic stem cell transplantation: Incidence in the context of immune recovery in two different transplantation settings.
2015 Scientific Article in PLoS Pathogens PLoS Pathog. 11:e1004906 (2015)
Latent membrane protein LMP2A impairs recognition of EBV-infected cells by CD8+ T cells.
2015 Scientific Article in PLoS Pathogens PLoS Pathog. 11:e1004910 (2015)
The EBNA-2 N-terminal transactivation domain folds into a dimeric structure required for target gene activation.
2015 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 21, 4440-4450 (2015)
Model matters: Differences in orthotopic rat hepatocellular carcinoma physiology determine therapy response to sorafenib.
2015 Scientific Article in Scientific Reports Sci. Rep. 5:10230 (2015)
Regulation of immunoproteasome function in the lung.
2015 Scientific Article in Plant Physiology Plant Physiol. 168, 859-870 (2015)
Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes and influences the chloroplast ultrastructure in poplar.
2015 Scientific Article in Journal of Pathology, The J. Pathol. 237, 123–132 (2015)
High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed paraffin-embedded clinical tissue samples.
2015 Scientific Article in Frontiers in Oncology Front. Oncol. 5:94 (2015)
Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas: An immunohistochemical study.
2015 Scientific Article in Nature Communications Nat. Commun. 6:7030 (2015)
Expression of the vault RNA protects cells from undergoing apoptosis.
2015 Scientific Article in Journal of Virology J. Virol. 89, 7248-7261 (2015)
K1 and K15 of Kaposi sarcoma-associated herpes virus are partial functional homologues of latent membrane protein 2A of Epstein-Barr virus.
2015 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 144, 147-156 (2015)
Supremacy of modern morphometry in typing renal oncocytoma and malignant look-alikes.
2015 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 290, 14668-14678 (2015)
Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility.
2015 Scientific Article in GigaScience GigaScience 4:20 (2015)
Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry.
2015 Meeting abstract in Bone Marrow Transplantation Bone Marrow Transplant. 50, S400 (2015)
T-cell receptor deep sequencing analysis of EBV specific T cells before and after adoptive transfer in a patient after allogeneic stem cell transplantation.
2015 Scientific Article in Theranostics Theranostics 5, 667-685 (2015)
Characterization of magnetic viral complexes for targeted delivery in oncology.
2015 Scientific Article in Journal of Enzyme Inhibition and Medicinal Chemistry J. Enzyme Inhib. Med. Chem. 30, 955-960 (2015)
Esterase activity of carbonic anhydrases serves as surrogate for selecting antibodies blocking hydratase activity.
2015 Scientific Article in Frontiers in Oncology Front. Oncol. 5:73 (2015)
Epstein-Barr virus in gastro-esophageal adenocarcinomas - single center experiences in the context of current literature.
2015 Scientific Article in Science Translational Medicine Sci. Transl. Med. 7:282ra47 (2015)
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high-grade B cell lymphoma.
2015 Scientific Article in Laboratory Investigation Lab. Invest. 95, 422-431 (2015)
MALDI Imaging mass spectrometry: Current frontiers and perspectives in pathology research and practice.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1295, 87-97 (2015)
Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1295, 75-86 (2015)
A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0120925 (2015)
An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging.
2015 Scientific Article in Blood Blood 125, 1601-1610 (2015)
Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4+ T cells.
2015 Scientific Article in Journal of Chemical Information and Modeling J. Chem. Inf. Model. 55, 294-307 (2015)
Discovery of small molecule CD40-TRAF6 inhibitors.
2015 Scientific Article in Angewandte Chemie - Internationale Edition Angew. Chem.-Int. Edit. 54, 4279-4283 (2015)
Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI.
2015 Scientific Article in Journal of Immunology J. Immunol. 194, 1434-1445 (2015)
Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumors.
2015 Scientific Article in Journal of Proteomics J. Proteomics 128, 321-332 (2015)
RNAi-mediated downregulation of poplar Plasma membrane Intrinsic Proteins (PIPs) changes plasma membrane proteome composition and affects leaf physiology.
2015 Scientific Article in PLoS Pathogens PLoS Pathog. 11:e1004640 (2015)
Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.
2015 Scientific Article in Journal of Immunology J. Immunol. 194, 1819-1831 (2015)
Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
2015 Scientific Article in OncoTarget Oncotarget 6, 4692-4703 (2015)
α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma.
2015 Scientific Article in Developmental Biology Dev. Biol. 399, 2-14 (2015)
Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling.
2015 Scientific Article in Gastroenterology Gastroenterology 148, 626-638 (2015)
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
2015 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 143, 453-462 (2015)
High-resolution MALDI mass spectrometric imaging of lipids in the mammalian retina.
2015 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 212, 37-52 (2015)
Loss of the Notch effector RBPJ promotes tumorigenesis.
2015 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 407, 2035-2045 (2015)
Discussion point: Reporting guidelines for mass spectrometry imaging.
2015 Scientific Article in International Journal of Cancer Int. J. Cancer 137, 1107-1118 (2015)
Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model.
2015 Scientific Article in Cancer Letters Cancer Lett. 356, 721-732 (2015)
Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 39-50 (2015)
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice.
2015 Scientific Article in Bioinformatics Bioinformatics 31, 933-939 (2015)
EVpedia: A community web portal for extracellular vesicles research.
2015 Scientific Article in Leukemia Leukemia 29, 828-838 (2015)
Dual PI3K/mTOR inhibition shows antileukemic activity in MLL rearranged acute myeloid leukemia.
2015 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 407, 2107-2116 (2015)
Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.
2015 Scientific Article in Journal of Hand Surgery : European Volume J. Hand Surg. Eur. 40, 591-596 (2015)
Anatomical and histomorphometric observations on the transfer of the anterior interosseous nerve to the deep branch of the ulnar nerve.
2015 Scientific Article in Oncogene Oncogene 34, 3917-3925 (2015)
CLIP2 as radiation biomarker in papillary thyroid carcinoma.
2015 Scientific Article in Oncogene Oncogene 34, 578–588 (2015)
Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model.
In: Proceedings (IEEE International Symposium on Biomedical Imaging, ISBI, 29. April - 02.May 2014, Beijing, China). Piscataway, NJ: IEEE, 2014. 1348-1351
Digital pathology: Multiple instance learning can detect Barrett's cancer.
2014 Meeting abstract in European Journal of Cancer Eur. J. Cancer 50, S161-S162 (2014)
uPAR and its interaction partners: potential new therapy targets in triple negative breast cancer.
2014 Meeting abstract in European Journal of Cancer Eur. J. Cancer 50, S113 (2014)
CLIP2 as radiation biomarker in papillary thyroid carcinoma.
2014 Meeting abstract in Blood Blood 124 (2014)
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high grade B-cell lymphoma.
2014 Meeting abstract in Blood Blood 124 (2014)
Analysis of the tissue-specific expression requirements and identification of cooperating mutations for leukemogenesis in an inducible CALM/AF10 knock-in mouse model.
2014 Meeting abstract in Blood Blood 124 (2014)
A mouse model for XLP-2 disease uncovers a critical function for IL-1beta and TNF in driving hyper-inflammation.
2014 Meeting abstract in Blood Blood 124 (2014)
Bioluminescence in vivo imaging improves the model of individual patients' AML cells growing in mice for sensitive and reliable preclinical treatment trials on various genetic subgroups.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2014, 128 S.
Eine seltene und sich langsam teilende Fraktion von Zellen der akuten lymphatischen Leukämie im Knochenmark von NSG-Mäusen ist chemoresistent.
München, Technische Universität, Fakultät für Medizin, Diss., 2014, 142 S.
Adoptive immunotherapy for treatment of chronic hepatitis B.
2014 Scientific Article in PLoS ONE PLoS ONE 9:e114918 (2014)
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.
2014 Scientific Article in Cell Cycle Cell Cycle 13, 3659-3669 (2014)
Checkpoint kinase 2 is required for efficient immunoglobulin diversification.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2014, 152 S.
The role of ORC6 in the human cell.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2014, 55 S.
Der konträre Einfluss von p53 auf die extrinsische und intrinsische Apoptoseinduktion in Tumorzellen.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2014, 207 S.
A systematical analysis of the signal transduction pathways induced by the Latent Membrane Protein 1 (LMP1) of Epstein-Barr virus.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2014, 115 S.
Towards comprehensive identification of proteins from MALDI imaging.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2014, 94 S.
Dissecting the role of selenothiol- versus thiol-based catalysis using the model enzyme glutathione peroxidase 4 (GPx4).
2014 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 37, 70 (2014)
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high grade B-cell lymphoma.
2014 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 37, 246 (2014)
Aberrant TNF signalling in dendritic cells in the absence of XIAP contributes to X-linked lymphoproliferative disease (XLP-2) by exaggerated necroptosis.
2014 Scientific Article in Journal of natural medicines J. Nat. Med. 20, 1401-1409 (2014)
Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.
2014 Scientific Article in Nature Cell Biology Nat. Cell Biol. 16, 1180-1191 (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
2014 Meeting abstract in Haematologica - The Hematology Journal Haematologica 99, 543 (2014)
Optimization of lentiviral transduction in patien-derived acute leukemia cells growing mice.
2014 Meeting abstract in Haematologica - The Hematology Journal Haematologica 99, 20 (2014)
Serial transplantation and in vivo monitoring of patient-derived xenografts: An advanced preclinical model to study diverse genetic AML subgroups in mice.
2014 Meeting abstract in Transplant international Transpl. Int. 27, 12 (2014)
Costimulation blockade by belatacept inhibits allo-specific de novo T cell responses and preserves virus-specific memory T cell responses in healthy donors and kidney transplanted patients.
2014 Review in World Journal of Gastroenterology World J. Gastroenterol. 20, 13648-13657 (2014)
Proteomic and metabolic prediction of response to therapy in gastric cancer.
2014 Scientific Article in DNA Repair DNA Repair 24, 63-72 (2014)
Analysis of SHPRH functions in DNA repair and immunoglobulin diversification.
2014 Scientific Article in Analytical Chemistry Anal. Chem. 86, 10568-10575 (2014)
A novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.
2014 Scientific Article in eLife eLife 3:e03842 (2014)
Flattop regulates basal body docking and positioning in mono- and multiciliated cells.
2014 Scientific Article in Journal of Virology J. Virol. 88, 14326-14339 (2014)
Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-epecific CD8 T cells.
2014 Scientific Article in Journal of Pathology, The J. Pathol. 235, 3-13 (2014)
De novo discovery of phenotypic intra-tumor heterogeneity using imaging mass spectrometry.
2014 Scientific Article in OncoTarget Oncotarget 5, 6620-6632 (2014)
Epidermal Growth Factor Receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy.
2014 Scientific Article in Journal of Immunology J. Immunol. 193, 4021-4031 (2014)
TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation.
2014 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 143, 1-9 (2014)
Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma.
2014 Scientific Article in Proteomics Proteomics 14, 2427-2431 (2014)
PAS-cal: A repetitive peptide sequence calibration standard for MALDI mass spectrometry.
2014 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 12:46 (2014)
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration.
2014 Meeting abstract in Experimental Hematology Exp. Hematol. 42, S28 (2014)
Identification and isolation of a rare population of low-cycling, self-renewing and drug-resistant acute lymphoblastic leukemia xenograft cells.
2014 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 42, 9700-9716 (2014)
Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1.
2014 Meeting abstract in American Journal of Transplantation Am. J. Transplant. 14, 36 (2014)
Belatacept can inhibit allo-specific T cell responses in a donor-dependent manner but preserves virus-specific memory T cell-responses.
2014 Scientific Article in Cancers Cancers 6, 1382-1393 (2014)
Heat Shock Protein 90 (HSP90) and Her2 in adenocarcinomas of the esophagus.
2014 Letter to the Editor in European Journal of Immunology Eur. J. Immunol. 44, 2521-2522 (2014)
To the editor: Murine gammaherpesvirus 68 (MHV-68) escapes from NK-cell-mediated immune surveillance by a CEACAM1-mediated immune evasion mechanism.
2014 Scientific Article in Mitochondrion Mitochondrion 19, 113-123 (2014)
Why to compare absolute numbers of mitochondria.
2014 Review in Bioanalysis Bioanalysis 6, 1241-1253 (2014)
In situ drug and metabolite analyzes in biological and clinical research by MALDI MS imaging.
2014 Scientific Article in Cancer Research Cancer Res. 74, 4318-4328 (2014)
B cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.
2014 Scientific Article in OncoTargets and Therapy OncoTargets Ther. 7, 789-798 (2014)
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma.
2014 Scientific Article in Journal of Virology J. Virol. 88, 9245-9259 (2014)
The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the toll-like receptor-induced proinflammatory cytokine response.
2014 Scientific Article in Cell Reports Cell Rep. 7, 1796-1808 (2014)
XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.
2014 Scientific Article in Journal of Immunology J. Immunol. 192, 5894-5905 (2014)
CD8 T cell-evasive functions of human cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity.
2014 Review in Histology and Histopathology Histol. Histopathol. 29, 1365-1376 (2014)
MALDI mass spectrometry imaging of formalin-fixed paraffin-embedded tissues in clinical research.
2014 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 142, 361-371 (2014)
A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.
2014 Scientific Article in Journal of Proteome Research J. Proteome Res. 13, 4730-4738 (2014)
Multicenter Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma.
2014 Scientific Article in Arthritis & Rheumatology Arthritis Rheum. 66, 2071-2078 (2014)
Optoacoustic imaging and staging of arthritic inflammation.
2014 Scientific Article in European Journal of Cancer Eur. J. Cancer 50, 1291-1300 (2014)
The role of tumour FoxP3 as prognostic marker in different subtypes of head and neck cancer.
2014 Scientific Article in Journal of Neurochemistry J. Neurochem. 130, 227-240 (2014)
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.
2014 Scientific Article in Biomaterials Biomaterials 35, 4345-4356 (2014)
All-in-One inducible lentiviral vector systems based on drug controlled FLP recombinase.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2014, 144 S.
TALE nucleases as antiviral factors.
2014 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 289, 10769-10784 (2014)
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
2014 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 42, 3666-3674 (2014)
Checkpoint kinase 1 negatively regulates somatic hypermutation.
2014 Scientific Article in Proteomics Proteomics 14, 913-923 (2014)
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry.
2014 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 42, 3059-3072 (2014)
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs.
2014 Scientific Article in American Journal of Nuclear Medicine and Molecular Imaging Am. J. Nucl. Med. Mol. Imaging 4, 70-79 (2014)
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma.
2014 Scientific Article in Circulation: Cardiovascular Imaging Circ.-Cardiovasc. Imaging 7, 321-329 (2014)
Assessment of myocardial infarction and post-infarction scar remodeling with an elastin-specific magnetic resonance agent.
2014 Scientific Article in Journal of Proteome Research J. Proteome Res. 13, 1138–1142 (2014)
MSiMass list: A public database of identifications for protein MALDI MSI.
2014 Scientific Article in Journal of Pathology, The J. Pathol. 232, 383-385 (2014)
In brief: The (molecular) pathogenesis of Barrett's oesophagus.
2014 Scientific Article in Oncogene Oncogene 44, 1258-1264 (2014)
Epstein-Barr virus maintains lymphomas via its miRNAs.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2013, 150 S.
Die Rolle der Checkpoint-Kinase 1 in der Immunglobulin-Diversifizierung.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2013, 163 S.
The T cell repertoire specific for the IE-1 protein of human cytomegalovirus: Diversity, function and evasion.
2013 Meeting abstract in Cancer Research Cancer Res. 73:3326 (2013)
TRAIL induces apoptosis preferentially in cell cycle arrested tumor cells, e.g., in tumor cells from children with acute lymphoblastic leukemia upon knockdown of cyclinE.
2013 Scientific Article in GIT : Labor-Fachzeitschrift GIT Fachz. Lab. 7, 444-447 (2013)
Bildgebende MS in biomedizinischer Forschung und Diagnostik.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2013, 133 S.
Deregulated notch and CD40 signaling in murine B lymphocytes.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2013, 143 S.
Die spezifische T-Zellantwort gegen das humane Herpesvirus 6B.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e82392 (2013)
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.
2013 Scientific Article in Anticancer Research Anticancer Res. 33, 5273-5287 (2013)
Activation of DNA damage response by antitumor therapy counteracts the activity of vinca alkaloids.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e80312 (2013)
An RNAi-based approach to down-regulate a gene family in vivo.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e80908 (2013)
Macrophage polarisation: An immunohistochemical approach for identifying M1 and M2 macrophages.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2013, 169 S.
Etablierung der Interaktion des viralen Onkoproteins LMP1 mit den zellulären Signalproteinen der TRAF-Proteinfamilie als Zielstruktur für Inhibitoren.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2013, 143 S.
Einfluss eines Carboanhydrase XII-spezifischen Antikörpers auf das Tumorwachstum in vitro und in vivo sowie Onkosomen-basierte Generierung neuer tumorreaktiver Antikörper.
2013 Scientific Article in Theranostics Theranostics 3, 903-913 (2013)
Cardioprotective C-kit+ bone marrow cells attenuate apoptosis after acute myocardial infarction in mice – in-vivo assessment with fluorescence molecular imaging.
2013 Scientific Article in British Journal of Cancer BJC Br. J. Cancer 109, 2714-2723 (2013)
MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion.
2013 Scientific Article in PLoS Pathogens PLoS Pathog. 9:e1003640 (2013)
A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.
2013 Scientific Article in PLoS Pathogens PLoS Pathog. 9:e1003636 (2013)
Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming.
2013 Scientific Article in PLoS Pathogens PLoS Pathog. 9:e1003638 (2013)
Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9.
2013 Scientific Article in Molecular Therapy Mol. Ther. 21, 2032-2042 (2013)
Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e56420 (2013)
AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma.
2013 Scientific Article in Frontiers in Immunology Front. Immunol. 4:33 (2013)
Neutrophils Activate Tumoral CORTACTIN to Enhance Progression of Orohypopharynx Carcinoma.
2013 Scientific Article in Cancer Research Cancer Res. 73, 6494-6503 (2013)
Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII.
2013 Scientific Article in Nature Methods Nat. Methods 10, 989-991 (2013)
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.
2013 Scientific Article in Virology Virology 443, 271-277 (2013)
Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α.
2013 Scientific Article in Analytical Biochemistry Anal. Biochem. 443, 66-74 (2013)
A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.
2013 Scientific Article in Journal of Proteomics J. Proteomics 91, 500-514 (2013)
MALDI-MS tissue imaging identification of biliverdin reductase B overexpression in prostate cancer.
2013 Scientific Article in Retrovirology Retrovirol. 10:85 (2013)
A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2013, 114 S.
MALDI imaging mass spectrometry in clinical proteomics research of gastric cancer tissues.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e70011 (2013)
Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.
2013 Review in Expert Review of Proteomics Expert Rev. Proteomics 10, 259-273 (2013)
Current frontiers in clinical research application of MALDI imaging mass spectrometry.
2013 Scientific Article in Cell Death & Disease Cell Death Dis. 4:e661 (2013)
Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis.
2013 Scientific Article in Current Opinion in Virology Curr. Opin. Virol. 3, 260-265 (2013)
Epstein-Barr virus and host cell methylation: Regulation of latency, replication and virus reactivation.
2013 Scientific Article in PLoS Pathogens PLoS Pathog. 9:e1003493 (2013)
The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e69098 (2013)
Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.
2013 Review in Histochemistry and Cell Biology Histochem. Cell Biol. 140, 93-104 (2013)
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels.
2013 Scientific Article in Hepatology Hepatology 57, 2469-2479 (2013)
Canonical notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1.
2013 Scientific Article in PLoS Pathogens PLoS Pathog. 9:e1003383 (2013)
Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.
2013 Scientific Article in PLoS Pathogens PLoS Pathog. 9:e1003336 (2013)
Abortive lytic reactivation of KSHV in CBF1/CSL deficient human B cell lines.
2013 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 12, 2901-2910 (2013)
Comprehensive identification of proteins from MALDI imaging.
2013 Scientific Article in Circulation Research Circ. Res. 113, 408-417 (2013)
Combined deficiency in glutathione peroxidase 4 and vitamin E causes multi-organ thrombus formation and early death in mice.
2013 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 11:27 (2013)
Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling.
2013 Scientific Article in Biochimica et Biophysica Acta - Biomembranes Biochim. Biophys. Acta-Biomembr. 1828, 2121-2133 (2013)
Progressive stages of mitochondrial destruction caused by cell toxic bile salts.
2013 Scientific Article in Photoacoustics Photoacoustics 1, 3-8 (2013)
Multispectral optoacoustic tomography of myocardial infarction.
2013 Scientific Article in Gastroenterology Gastroenterology 145, 456-465 (2013)
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.
2013 Scientific Article in Acta Neuropathologica Acta Neuropathol. 125, 671-681 (2013)
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
2013 Scientific Article in Molecular Cancer Mol. Cancer 12:28 (2013)
The impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) in human breast cancer.
2013 Scientific Article in Journal of Proteome Research J. Proteome Res. 12, 2700-2714 (2013)
PPAR alpha: A novel radiation target in locally exposed Mus musculus heart revealed by quantitative proteomics.
2013 Scientific Article in PLoS ONE PLoS ONE 8:e58439 (2013)
X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.
2013 Scientific Article in Science Signaling Sci. Signal. 6:ra27 (2013)
Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif.
2013 Scientific Article in Journal of Pathology, The J. Pathol. 230, 410-419 (2013)
Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria.
2013 Scientific Article in British Journal of Pharmacology Br. J. Pharmacol. 168, 1558-1569 (2013)
Enhanced anti-tumour effects of vinca alkaloids given separately from cytostatic therapies.
2013 Scientific Article in Oncogene Oncogene 32, 641-650 (2013)
EpCAM regulates cell cycle progression via control of cyclin D1 expression.
2013 Scientific Article in Journal of Virology J. Virol. 87, 4596-4608 (2013)
Systemic and local infection routes govern different cellular dissemination pathways during gammaherpesvirus infection in vivo.
2013 Scientific Article in Tumor Biology Tumor Biol. 34, 437-443 (2013)
CD133 induces tumour-initiating properties in HEK293 cells.
2013 Scientific Article in Journal of Proteomics J. Proteomics 90, 52-60 (2013)
MRI-compatible pipeline for three-dimensional MALDI imaging mass spectrometry using PAXgene fixation.
2013 Scientific Article in Cold Spring Harbor Perspectives in Biology Cold Spring Harbor Perspect. Biol. 5:a013029 (2013)
Replication of Epstein-Barr viral DNA.
2013 Letter to the Editor in Journal of Virology J. Virol. 87, 3616-3617 (2013)
Testing for herpesvirus infection is essential in children with chromosomal-instability syndromes.
2013 Review in Clinical Biochemistry Clin. Biochem. 46, 539-545 (2013)
MALDI imaging mass spectrometry in cancer research: Combining proteomic profiling and histological evaluation.
2013 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 931, 537-546 (2013)
MALDI imaging mass spectrometry for direct tissue analysis.
2013 Scientific Article in Journal of General Virology J. Gen. Virol. 94, 376-386 (2013)
Suppression of CD8+ T cell recognition in the immediate-early phase of human cytomegalovirus infection.
2013 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 123, 469-478 (2013)
P62 links β-adrenergic input to mitochondrial function and thermogenesis.
2013 Scientific Article in Nature Structural & Molecular Biology Nat. Struct. Mol. Biol. 20, 73-81 (2013)
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.
2013 Scientific Article in Neuropathology and Applied Neurobiology Neuropathol. Appl. Neurobiol. 39, 256-269 (2013)
Characterization of MENX-associated pituitary tumours.
2013 Scientific Article in Human Pathology Hum. Pathol. 44, 829-836 (2013)
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: Loss of PTEN is associated with worse clinical outcome.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2012, 123 S.
Die Rolle der Raf-Kinasen in der B-Zell-Entwicklung und -Aktivierung.
2012 Meeting abstract in Klinische Pädiatrie Klin. Padiatr. 224, 218 (2012)
TRAIL targets cell cycle arrested tumor cells.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2012, 158 S.
Aufklärung der Funktion virus-kodierter miRNAs während einer Gammaherpesvirus-Infektion anhand des murinen Gammaherpesvirus 68 (MHV-68) als Modell.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2012, 105 S.
Die Charakterisierung des rezeptornahen Signalweges der TRAIL-induzierten Aktivierung von NF-κB.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2012, 137 S.
The role of the herpesviral proteins LMP2A, K1, and K15 during oncogenic transformation of primary B cells.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2012, 140 S.
Functions of the germinal center kinase TNIK in signal transduction of the viral oncoprotein LMP1 and the related CD40 receptor.
2012 Scientific Article in Analytical Chemistry Anal. Chem. 84, 3716-3724 (2012)
Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans.
2012 Scientific Article in Cancer Biomarkers Cancer Biomark. 12, 97-105 (2012)
CD133 is a predictor of poor survival in head and neck squamous cell carcinomas.
2012 Scientific Article in European Journal of Immunology Eur. J. Immunol. 42, 2901-2912 (2012)
Specific CD8+ T cells recognize human herpesvirus 6B.
2012 Scientific Article in PLoS Pathogens PLoS Pathog. 8:e1002704 (2012)
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination.
2012 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 10:43 (2012)
Global gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lymphomas.
2012 Scientific Article in PLoS ONE PLoS ONE 7:e52798 (2012)
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
2012 Scientific Article in Cancer Biology & Therapy Cancer Biol. Ther. 13, 1425-1435 (2012)
Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo.
2012 Scientific Article in Translational Oncology Transl. Oncol. 5, 98-104 (2012)
uPA and PAI-1-related signaling pathways differ between primary breast cancers and lymph node metastases.
2012 Scientific Article in Anticancer Research Anticancer Res. 32, 4251-4261 (2012)
Glucocorticoids augment survival and proliferation of tumor cells.
2012 Scientific Article in Cell Death & Disease Cell Death Dis. 3:e414 (2012)
The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL.
2012 Scientific Article in European Journal of Immunology Eur. J. Immunol. 42, 3167-3173 (2012)
Mature proteins derived from Epstein-Barr virus fail to feed into the MHC class I antigenic pool.
2012 Scientific Article in Journal of Pathology, The J. Pathol. 228, 459-470 (2012)
Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.
2012 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 18, 6426-6435 (2012)
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.
2012 Scientific Article in European Journal of Nuclear Medicine and Molecular Imaging Eur. J. Nucl. Med. Mol. Imaging 40, 34-43 (2012)
[18F]FLT is superior to [18F]FDG for predicting early response to antiproliferative treatment in high-grade lymphoma in a dose-dependent manner.
2012 Scientific Article in Journal of Immunology J. Immunol. 189, 3795-3799 (2012)
Cutting edge: MiR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production.
2012 Scientific Article in PLoS Pathogens PLoS Pathog. 8:e1002902 (2012)
BZLF1 governs CpG-methylated chromatin of Epstein-Barr virus reversing epigenetic repression.
2012 Scientific Article in Protein Expression and Purification Protein Expr. Purif. 86, 7-11 (2012)
Efficient expression and purification of tag-free Epstein-Barr virus EBNA1 protein in Escherichia coli by auto-induction.
2012 Scientific Article in Virology Journal Virol. J. 9:107 (2012)
Murine gammaherpesvirus 68 glycoprotein 150 does not contribute to latency amplification in vivo.
2012 Scientific Article in Hepatology Hepatology 56, 873-883 (2012)
Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.
2012 Scientific Article in Journal of Cell Biology, The J. Cell Biol. 198, 509-528 (2012)
Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus.
2012 Scientific Article in PLoS ONE PLoS ONE 7:e42021 (2012)
Humanized c-Myc mouse.
2012 Scientific Article in PLoS ONE PLoS ONE 7:e41420 (2012)
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.
2012 Scientific Article in European Journal of Nuclear Medicine and Molecular Imaging Eur. J. Nucl. Med. Mol. Imaging 39, 1886-1897 (2012)
Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.
2012 Scientific Article in Cancer Research Cancer Res. 72, 5014-5024 (2012)
FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.
2012 Scientific Article in PLoS Biology PLoS Biol. 10:e1001376 (2012)
The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.
2012 Scientific Article in PLoS ONE PLoS ONE 7:e41341 (2012)
Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.
2012 Scientific Article in Gastroenterology Gastroenterology 143, 544-549 (2012)
Direct molecular tissue analysis by MALDI imaging mass spectrometry in the field of gastrointestinal disease.
2012 Scientific Article in Journal of Nuclear Cardiology J. Nucl. Cardiol. 19, 775-784 (2012)
Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques.
2012 Scientific Article in Cell Death & Disease Cell Death Dis. 3, e327:e327 (2012)
NOXA as critical mediator for drug combinations in polychemotherapy.
2012 Scientific Article in Analytical Chemistry Anal. Chem. 84, 6079-6087 (2012)
Exploring three-dimensional matrix-assisted laser desorption/ionization imaging mass spectrometry data: Three-dimensional spatial segmentation of mouse kidney.
2012 Scientific Article in Modern Pathology Mod. Pathol. 25, 522-528 (2012)
Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma.
2012 Scientific Article in Blood Blood 119, 3440-3449 (2012)
TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
2012 Scientific Article in Molecular Endocrinology Mol. Endocrinol. 26, 819-832 (2012)
Bile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding protein.
2012 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 10:8 (2012)
Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice.
2012 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 109, E1396-E1404 (2012)
RNAs in Epstein-Barr virions control early steps of infection.
2012 Scientific Article in Journal of Virology J. Virol. 86, 447-458 (2012)
The lytic phase of Epstein-Barr virus requires a viral genome with 5-methylcytosine residues in CpG sites.
2012 Scientific Article in PLoS ONE PLoS ONE 7:e39424 (2012)
MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.
2012 Scientific Article in Blood Blood 119, 4224-4227 (2012)
Leukemia-initiating cells of patient-derived acute lymphoblastic leukemia xenografts are sensitive toward TRAIL.
2012 Scientific Article in Journal of General Virology J. Gen. Virol. 93, 1076-1080 (2012)
ORF23 of murine gammaherpesvirus 68 is non-essential for in vitro and in vivo infection.
2012 Scientific Article in Journal of Cancer Research and Clinical Oncology J. Cancer Res. Clin. Oncol. 138, 843-858 (2012)
Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines.
2012 Scientific Article in Biological Chemistry Biol. Chem. 393, 391-401 (2012)
Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients.
2012 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 209, 819-835 (2012)
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.
2012 Scientific Article in PLoS ONE PLoS ONE 7:e31310 (2012)
Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease.
2012 Scientific Article in Annals of Oncology Ann. Oncol. 23, 2185-2190 (2012)
High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients.
2012 Scientific Article in Journal of Proteomics J. Proteomics 75, 4693-4704 (2012)
MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma.
2012 Scientific Article in Journal of Proteome Research J. Proteome Res. 11, 1996-2003 (2012)
Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging.
2012 Scientific Article in Nanomedicine Nanomed. 7, 855-865 (2012)
Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages.
2012 Scientific Article in Journal of Cellular Physiology J. Cell. Physiol. 227, 204-212 (2012)
Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR.
2012 Scientific Article in Science Science 335, 984-989 (2012)
The alarmin interleukin-33 drives protective antiviral CD8+ T cell responses.
2012 Scientific Article in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 366, 44-53 (2012)
TFAP2E-DKK4 and chemoresistance in colorectal cancer.
2012 Scientific Article in Leukemia Leukemia 26, 1020-1029 (2012)
RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis.
2012 Scientific Article in Journal of Pathology, The J. Pathol. 226, 723-734 (2012)
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: A comparative study in transgenic mice and human tissues.
2012 Scientific Article in Clinical and Experimental Ophthalmology Clin. Experiment. Ophthalmol. 40, 87-97 (2012)
Filtering blue light reduces light-induced oxidative stress, senescence, and accumulation of extracellular matrix proteins in human retinal pigment epithelium cells.
2012 Scientific Article in European Journal of Cell Biology Eur. J. Cell Biol. 91, 97-101 (2012)
Virus-specific T cells for therapy - approaches, problems, solutions.
2012 Scientific Article in European Journal of Cell Biology Eur. J. Cell Biol. 91, 65-69 (2012)
Human B cells on their route to latent infection - early but transient expression of lytic genes of Epstein-Barr virus.
2012 Scientific Article in Journal of Molecular Medicine J. Mol. Med. 90, 163-174 (2012)
S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI Imaging.
München, Technische Universität München, Wissenschaftszentrum Weihenstephan für Ernährung, Landnutzung und Umwelt, Diss., 2011, 109 S.
The role of AID and NF-κB for B cell development and lymphomagenesis.
2011 Scientific Article in BMC Cancer BMC Cancer 11:509 (2011)
Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: Results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).
2011 Scientific Article in Anticancer Research Anticancer Res. 31, 3315-3321 (2011)
Biodistribution of 131I-labeled anti-CK8 monoclonal antibody in HNSCC in xenotransplanted SCID mice.
2011 Scientific Article in OncoTarget Oncotarget 2, 970-975 (2011)
CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients.
2011 Scientific Article in LC GC North America LC GC N. Am. Suppl. S, Suppl., 21-28 (2011)
Matrix-assisted laser desorption-ionization imaging mass spectrometry for direct tissue analysis.
2011 Scientific Article in Journal of Gastrointestinal Surgery J. Gastrointest. Surg. 15, 29-37 (2011)
Detection of lymph node involvement by cytokeratin immunohistochemistry is an independent prognostic factor after curative resection of esophageal cancer.
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MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissues.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2011, 178 S.
Identifizierung von BZLF1-regulierten Promotoren des Epstein-Barr Virus.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2011, 136 S.
Die Expression von LMP1, LMP2A und CD30 in B-Zellen zur Analyse physiologischer und pathogener Effekte.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2011, 143 S.
RNA transfer by Epstein-Barr virus triggers early events that regulate cell fate and promote immune evasion.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2011, 139 S.
Acquisition and loss of chromatin modifications during an Epstein-Barr Virus infection.
München, Ludwig-Maximilians-Universität, Medizinische Fakultät, Diss., 2011, 79 S.
Downregulation of endogenous TRAIL and its effect on the human cancer cell line KELLY.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2011, 170 S.
Das Kaposi-Sarkom assoziierte herpesvirale Protein vIRF4 als Interaktionspartner des zellulären DNA-Bindeproteins CBF1 und seine Rolle als transkriptioneller Regulator zellulärer Zielgene.
2011 Scientific Article in Laryngo-Rhino-Otologie Laryngol. Rhinol. Otol. 90, 168-177 (2011)
Moderne Methoden der Biomarkerentwicklung: eine Chance für die individualisierte Tumortherapie?
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2011, 152 S.
Charakterisierung der Rolle des zellulären Transkriptionsfaktors CSL/CBF1 im lytischen Zyklus KSHV-infizierter B-Zellen.
2011 Scientific Article in Circulation Circulation 124, 2892-2902 (2011)
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection.
2011 Scientific Article in Blood Blood 118, 6123-6131 (2011)
Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule.
2011 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 17, 7605-7613 (2011)
Important role of Caspase-8 for chemo-sensitivity of ALL cells.
2011 Scientific Article in Investigative Ophthalmology & Visual Science, IOVS Invest. Ophthalmol. Vis. Sci. 52, 7822-7834 (2011)
Immunocytochemical and ultrastructural evidence of glial cells and hyalocytes in internal limiting membrane specimens of idiopathic macular holes.
2011 Scientific Article in Neoplasia : An International Journal for Oncology Research Neoplasia 13, 971-979 (2011)
Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis.
2011 Scientific Article in Annals of Thoracic Surgery Ann. Thorac. Surg. 91, 1025-1031 (2011)
Clinical significance of the costimulatory molecule B7-H1 in Barrett carcinoma.
2011 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 121, 1508-1518 (2011)
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.
2011 Scientific Article in Journal of Virology J. Virol. 85, 13105-13113 (2011)
A virus-like particle-based Epstein-Barr virus vaccine.
2011 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 136, 227-244 (2011)
MALDI imaging mass spectrometry for direct tissue analysis: Technological advancements and recent applications.
2011 Scientific Article in Biochemical Journal / Reviews Biochem. J. 438, 315-323 (2011)
Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage.
2011 Scientific Article in Journal of Proteomics J. Proteomics 75, 237-245 (2011)
Super-resolution segmentation of imaging mass spectrometry data: Solving the issue of low lateral resolution.
2011 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 10:M111.011635 (2011)
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.
2011 Scientific Article in Pharmazie in Unserer Zeit Pharm. Unserer Zeit 40, 240-246 (2011)
Lebenslange Heilung mittels Gentransfer - Realität oder Utopie? Stabiler versus transienter Gentransfer.
2011 Scientific Article in Science Science 334, 686-690 (2011)
Drosophila CENH3 is sufficient for centromere formation.
2011 Scientific Article in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 68, 3741-3756 (2011)
Different roles of the human Orc6 protein in the replication initiation process.
2011 Scientific Article in American Journal of Pathology, The Am. J. Pathol. 179, 2720-2729 (2011)
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer.
2011 Scientific Article in Blood Blood 118, 6321-6331 (2011)
CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling.
2011 Scientific Article in PLoS ONE PLoS ONE 6:e25294 (2011)
EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells - a new option for the treatment of B-CLL.
2011 Scientific Article in Modern Pathology Mod. Pathol. 24, 908-916 (2011)
Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.
2011 Scientific Article in Analytical Cellular Pathology Anal. Cell. Pathol. 34, 21-33 (2011)
Nuclear position and shape deformation of chromosome 8 territories in pancreatic ductal adenocarcinoma.
2011 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 401, 167-181 (2011)
Normalization in MALDI-TOF imaging datasets of proteins: Practical considerations.
2011 Scientific Article in PLoS ONE PLoS ONE 6:e18609 (2011)
The dyad symmetry element of Epstein-Barr virus is a dominant but dispensable replication origin.
2011 Letter to the Editor in Blood Blood 117, 1777-1778 (2011)
What keeps the power on in lymphomas? (Comment on Vereide and Sudgen, page 1977)
2011 Scientific Article in Oncogene Oncogene 30, 1831-1840 (2011)
High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
2011 Scientific Article in Blood Blood 117, 3780-3792 (2011)
Programming of marginal zone B-cell fate by basic Krüppel-like factor (BKLF/KLF3).
2011 Scientific Article in Leukemia and Lymphoma Leuk. Lymphoma 52, 458-466 (2011)
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus.
2011 Scientific Article in Applied Immunohistochemistry & Molecular Morphology Appl. Immunohistochem. 19, 300-305 (2011)
Protein microarray-based comparison of HER2, estrogen receptor, and progesterone receptor status in core biopsies and surgical specimens from FFPE breast cancer tissues.
2011 Scientific Article in Glia Glia 59, 697-707 (2011)
Differential expression of inwardly rectifying K+ channels and aquaporins 4 and 5 in autoimmune uveitis indicates misbalance in Müller glial cell-dependent ion and water homeostasis.
2011 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 60, 649-658 (2011)
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII.
2011 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 60, 639-648 (2011)
Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC.
2011 Scientific Article in Molecular Cancer Mol. Cancer 10:28 (2011)
Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities.
2011 Scientific Article in European Heart Journal Eur. Heart J. 32, 1121-1133 (2011)
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy.
2011 Scientific Article in Journal of Cell Science J. Cell Sci. 124, 1245-1255 (2011)
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
2011 Scientific Article in Blood Blood 117, 519-529 (2011)
Immune modulation by Fas ligand reverse signaling: Lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.
2011 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 10:M110.005991 (2011)
Revisiting rat spermatogenesis with MALDI imaging at 20- μm resolution.
2011 Scientific Article in Journal of Pathology, The J. Pathol. 223, 54-63 (2011)
Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: New insights from protein microarray analysis.
2011 Scientific Article in Journal of Cellular and Molecular Medicine J. Cell. Mol. Med. 15, 874-887 (2011)
In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody.
2010 Scientific Article in Expert Review of Proteomics Expert Rev. Proteomics 7, 927-941 (2010)
Approaching MALDI molecular imaging for clinical proteomic research: Current state and fields of application.
München, Ludwig-Maximilians-Universität München, Fakultät für Biologie, Diss., 2010, 154 S.
Die Ausbildung von Pre-Replikationskomplexen im Epstein-Barr-Virus und dem Menschen: Eine Genom-weite Analyse.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2010, 133 S.
Mechanismen der Apoptoseinduktion: Betulinsäure in Kombination mit konventionellen Zytostatika auf Leukämiezellen.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2010, 155 S.
Angeborene und adaptive Immunreaktionen in der Frühphase der Epstein-Barr-Virus-Infektion.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2010, 132 S.
Das Latente Membranprotein 2A des Epstein-Barr Virus und der humane B-Zell-Rezeptor: Ein Vergleich.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2010, 169 S.
Induktion Epstein-Barr Virus-spezifischer Immunantworten durch Exosomen und Virus-like Particles.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2010, 134 S.
Herpesvirusspezifische T-Zellen für die Immuntherapie: Von ihrer Identifikation zum Transfer ihrer Spezifität.
Hohenheim, Universität Hohenheim, Fakultät Naturwissenschaften, Diss., 2010, 131 S.
Glucocorticoid-induziertes Wachstum von Tumorzellen: Systematische Quantifizierung, Signalmechanismen und Inhibition.
2010 Scientific Article in HNO HNO 58, 713-723 (2010)
[Diagnostic and prognostic biomarkers in head and neck squamous cell carcinoma].
2010Vortrag: Molekulare Bildgebung 2010, 4-6 November 2010, Seeon. (2010)
Classification of HER2/neu Status in Gastric cancer using a Breast Cancer Derived Proteome Classifier.
2010Vortrag: 14th International Congress of Immunology, 22- 27 August 2010, Kobe, Japan. (2010)
The impact of BCRF1 (viral IL-10) and BNLF2a on the immune evasion of Epstein Barr Virus.
2010 Scientific Article in Journal of Proteome Research J. Proteome Res. 9, 5188-5196 (2010)
Proteomic analysis of PAXgene-fixed tissues.
In: Robertson, E.S.* [Eds.]: Epstein-Barr Virus. Latency and Transformation. Norfolk: Caister Academic Press, 2010. 61-80
EBNA-2 in Transcription activation of viral and cellular.
2010 Scientific Article in BMC Cancer BMC Cancer 10:608 (2010)
High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma.
2010 Scientific Article in Journal of Virology J. Virol. 84, 12255-12264 (2010)
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling.
2010 Scientific Article in PLoS Pathogens PLoS Pathog. 6, 69-70:e1001063 (2010)
Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells.
2010 Scientific Article in Journal of Virology J. Virol. 84, 3612-3623 (2010)
Toll-like receptor agonists synergistically increase proliferation and activation of B cells by Epstein-Barr virus.
2010 Scientific Article in Virchows Archiv Virchows Arch. 457, 705-713 (2010)
Interaction of Snail and p38 mitogen-activated protein kinase results in shorter overall survival of ovarian cancer patients.
2010 Scientific Article in Journal of Morphology J. Morphol. 271, 1509-1526 (2010)
Developmental expression of neuromodulators in the central complex of the grasshopper Schistocerca gregaria.
2010 Scientific Article in Pathologe, Der Pathologe 31, (Suppl.2), 263-267 (2010)
Neues zur Proteinanalytik archivierter Gewebeproben.
2010 Scientific Article in Journal of Neuroscience J. Neurosci. 30, 13794-13807 (2010)
RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.
2010 Scientific Article in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 67, 4249-4256 (2010)
Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes.
2010 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 107, 13438-13443 (2010)
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
2010 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 207, 1031-1044 (2010)
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.
2010 Scientific Article in PLoS ONE PLoS ONE 5:e13578 (2010)
Identification of epidermal pdx1 expression discloses different roles of notch1 and notch2 in murine KrasG12D-induced skin carcinogenesis in vivo.
2010 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 9, 2292-2305 (2010)
Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry.
2010 Scientific Article in PLoS Pathogens PLoS Pathog. 6, e1001114 (2010)
CpG-methylation regulates a class of Epstein-Barr virus promoters.
2010 Scientific Article in Virchows Archiv Virchows Arch. 457, 299-307 (2010)
HER2 diagnostics in gastric cancer-guideline validation and development of standardized immunohistochemical testing.
2010 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 16, 4256-4267 (2010)
Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma.
2010 Scientific Article in British Journal of Cancer BJC Br. J. Cancer 103, 663-667 (2010)
In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues.
2010 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 107, 850-855 (2010)
AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome.
2010 Scientific Article in Journal of Virology J. Virol. 84, 2533-2546 (2010)
The latent origin of replication of Epstein-Barr virus directs viral genomes to active regions of the nucleus.
2010 Scientific Article in Chromosome Research Chromosome Res. 18, 63-77 (2010)
Why are we where we are? Understanding replication origins and initiation sites in eukaryotes using ChIP-approaches.
2010 Review in Cell Communication and Signaling Cell Commun. Signal. 8:2 (2010)
Signal transduction, receptors, mediators and genes: Younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology.
2010 Scientific Article in Journal of Proteome Research J. Proteome Res. 9, 1854-1863 (2010)
Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry.
2010 Scientific Article in Journal of natural medicines J. Nat. Med. 16, 75-82 (2010)
Platelets contribute to postnatal occlusion of the ductus arteriosus.
2010 Scientific Article in Virology Virology 397, 299-310 (2010)
Asymmetric Arginine dimethylation of Epstein-Barr virus nuclear antigen 2 promotes DNA targeting.
2010 Scientific Article in International Journal of Cancer Int. J. Cancer 126, 2216-2228 (2010)
Small molecule XIAP inhibitors sensitize childhood acute leukemia cells for CD95-induced apoptosis.
2010 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 17, 87-98 (2010)
Novel gene rearrangements in transformed breast cells identified by high-resolution breakpoint analysis of chromosomal aberrations.
2010 Scientific Article in International Journal of Cancer Int. J. Cancer 126, 2362-2372 (2010)
Allelic loss of chromosomes 8 and 19 in MENX-associated rat pheochromocytoma.
2009 Scientific Article in Circulation: Cardiovascular Imaging Circ.-Cardiovasc. Imaging 2, 331-338 (2009)
Evaluation of ανβ₃ integrin-targeted positron emission tomography tracer ¹⁸F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice.
2009 Scientific Article in PLoS Biology PLoS Biol. 7:e1000240 (2009)
Cadherin-2 controls directional chain migration of cerebellar granule neurons.
2009 Scientific Article in Journal of Immunology J. Immunol. 183, 6819-6830 (2009)
CMV-specific TCR-transgenic T cells for immunotherapy.
2009 Scientific Article in Journal of Cellular and Molecular Medicine J. Cell. Mol. Med. 13, 3858-3867 (2009)
Activation of epidermal growth factor receptor results in snail protein but not mRNA over-expression in endometrial cancer.
2009 Scientific Article in Blood Blood 113, 1710-1722 (2009)
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance.
2009 Scientific Article in PLoS Pathogens PLoS Pathog. 5:e1000506 (2009)
Differential gene expression patterns of EBV infected EBNA-3A positive and negative human B lymphocytes.
2009 Review in Cell Communication and Signaling Cell Commun. Signal. 7:2 (2009)
Signal transduction in the footsteps of Goethe and Schiller.
2009 Scientific Article in Journal of Immunotherapy J. Immunother. 32, 310-321 (2009)
Activated human γδ T cells as stimulators of specific CD8⁺ T-cell responses to subdominant Epstein Barr virus epitopes: Potential for immunotherapy of cancer.
2009 Scientific Article in Virchows Archiv Virchows Arch. 455, 191-192 (2009)
Protein analysis of tissues - current views and clinical perspectives.
2009 Scientific Article in Pathologe, Der Pathologe 30, (Suppl.2), 140-145 (2009)
In-situ-Proteomanalyse von Geweben: Mittels bildgebender Massenspektrometrie (MALDI Imaging)
2009 Scientific Article in Journal of Immunology J. Immunol. 182, 4538-4546 (2009)
Induction of tumor cell apoptosis or necrosis by conditional expression of cell death proteins: Analysis of cell death pathways and in vitro immune stimulatory potential.
2009 Scientific Article in Journal of Virology J. Virol. 83, 5014-5027 (2009)
C-Myc and Rel/NF-κB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells.
2009 Scientific Article in Virchows Archiv Virchows Arch. 455, 117-123 (2009)
Overexpression of PTK6 (breast tumor kinase) protein - a prognostic factor for long-term breast cancer survival - is not due to gene amplification.
2009 Scientific Article in Blood Blood 113, 5506-5515 (2009)
Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells.
2009 Scientific Article in Science Signaling Sci. Signal. 2, mr3:mr3 (2009)
Signal transduction - receptors, mediators, and genes.
München, Ludwig-Maximilians-Universität München, Fakultät für Biologie, Diss., 2009, 139 S.
Funktionelle Charakterisierung der EBV-nukleären Antigene 3A und 3C (EBNA3A und EBNA3C).
2009 Scientific Article in Experimental Cell Research Exp. Cell Res. 315, 1759-1771 (2009)
Tumor suppressor KAI1 affects integrin alphavbeta3-mediated ovarian cancer cell adhesion, motility, and proliferation.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2009, 181 S.
Cellular and molecular characterisation of novel lipopeptides with anti-myeloma activities.
2009 Scientific Article in Head and Neck Head Neck 31, 371-380 (2009)
Conditional immortalization of human B cells by CD40 ligation.Tumor-derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression.
2009 Scientific Article in Experimental Cell Research Exp. Cell Res. 315, 1759-1771 (2009)
Tumor suppressor KAI1 affects integrin αvβ3-mediated ovarian cancer cell adhesion, motility, and proliferation.
2009Vortrag: Einladung zum Seminarvortrag, 22nd October 2009, Hamburg, Germany. (2009)
The EBV-genome comes of age: Taking advantage of an extrachromosomal virus to understand nuclear processes.
2009Vortrag: KSHV 12th International Workshop, 13-16 September 2009, Charleston, South Carolina, USA. (2009)
KSHV lytic vIRF4 (K10.1), a novel target gene of Rta and potential modulator of Rta mediated transactivation via the host CSL/CBF1 protein.
2009Vortrag: Eukaryotic DNA Replication and Genome Maintenance, 1-5 September 2009, Cold Spring Harbor, NY, USA. (2009)
Dual role of human Orc6 in origin activation.
2009 Scientific Article in Mammalian Genome Mamm. Genome 20, 664-673 (2009)
Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes.
2009 Scientific Article in Hepatology Hepatology 49, 979-988 (2009)
Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.
2009 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 131, 537-551 (2009)
Molecular mapping deep within a living human organ: Analysis of microvessel function on the timescale of seconds and with sub-micrometre spatial resolution.
2009 Scientific Article in European Journal of Obstetrics & Gynecology and Reproductive Biology Eur. J. Obstet. Gynecol. Reprod. Biol. 144, (Suppl.1), S114-S120 (2009)
Imaging of placental transport mechanisms: A review.
2009 Scientific Article in PLoS ONE PLoS ONE 4:e6011 (2009)
Disassembly of shank and homer synaptic clusters is driven by soluble β-amyloid₁₋₄₀ through divergent NMDAR-dependent signalling pathways.
2009 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 18, 3632-3644 (2009)
Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.
2009 Scientific Article in FASEB Journal FASEB J. 23, 3233-3242 (2009)
Mitochondrial glutathione peroxidase 4 disruption causes male infertility.
2009 Scientific Article in Nature Cell Biology Nat. Cell Biol. 11, 162-171 (2009)
Nuclear signalling by tumour-associated antigen EpCAM.
2009 Review in Nature Reviews - Gastroenterology & Hepatology Nat. Rev. Gastroenterol. Hepatol. 6, 170-183 (2009)
Proteomic and metabolic prediction of response to therapy in gastrointestinal cancers.
2009 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 106, 3354-3359 (2009)
Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion.
2009 Scientific Article in Laboratory Investigation Lab. Invest. 89, 385-397 (2009)
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays.
2009 Scientific Article in Acta Oto-Laryngologica Acta Otolaryngol. 129, 205-213 (2009)
Centrosome abnormalities in head and neck squamous cell carcinoma (HNSCC).
2008 Scientific Article in Current Gene Therapy Curr. Gene Ther. 8, 147-161 (2008)
Episomal vectors for gene therapy.
2008 Scientific Article in Biological Chemistry Biol. Chem. 389, 1261-1271 (2008)
Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1.
2008 Scientific Article in EMBO Journal, The EMBO J. 27, 3024-3035 (2008)
RNA-dependent recruitment of the origin recognition complex.
2008 Scientific Article in Journal of Infectious Diseases, The J. Infect. Dis. 198, 1536-1544 (2008)
Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.
2008 Scientific Article in Pharmaceutical Research Pharm. Res. 25, 2946-2962 (2008)
A fibrin glue composition as carrier for nucleic acid vectors.
2008 Scientific Article in European Urology Eur. Urol. 54, 1179-1187 (2008)
GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves.
2008 Scientific Article in Human Pathology Hum. Pathol. 39, 1621-1629 (2008)
Microarray comparative genomic hybridization analysis of tubular breast carcinoma shows recurrent loss of the CDH13 locus on 16q.
2008 Scientific Article in Neurocritical Care Neurocrit. Care 9, 387-393 (2008)
Cerebral Ischemia and Neurogenesis: A Two-time Comparison.
2008 Scientific Article in Circulation Research Circ. Res. 102, 302-309 (2008)
Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.
2008 Scientific Article in British Journal of Cancer BJC Br. J. Cancer 99, 1089-1095 (2008)
Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients.
2008 Meeting abstract in Bone Marrow Transplantation Bone Marrow Transplant. 41, S127-S128 (2008)
Tolerance in DLA-haploidentical canine littermates following CD6-depleted marrow transplantation and donor lymphocyte transfusion.
2008 Scientific Article in Breast Journal, The Breast J. 14, 487-491 (2008)
A Case of Heterogeneous Breast Cancer with Clonally Expanded T-Cells in the HER2+ and Metastasis of the HER2- Tumor Cells.
2008 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 130, 421-434 (2008)
MALDI imaging mass spectrometry for direct tissue analysis: A new frontier for molecular histology.
2008 Scientific Article in Journal of Molecular Medicine J. Mol. Med. 86, 1353-1365 (2008)
Chromosomal changes characterize head and neck cancer with poor prognosis.
2008 Scientific Article in Leukemia Leukemia 22, 1737-1745 (2008)
Spongistatin 1: A new chemosensitizing marine compound that degrades XIAP.
2008 Scientific Article in Oncogene Oncogene 27, 783-793 (2008)
Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells.
Methods in Molecular Biology In: Posch, A.* [Eds.]: 2D Page: Sample Preparation and Fractionation. Totowa, NJ: Humana Press, 2008. 333-348 (Methods Mol. Biol. ; 424)
Isolation of highly pure rat liver mitochondria with the aid of zone-electrophoresis in a free flow device (ZE-FFE).
2008 Scientific Article in EMBO Reports EMBO Rep. 9, 377-383 (2008)
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.
2008 Scientific Article in Analytical Chemistry Anal. Chem. 80, 5051-5058 (2008)
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition.
2008 Scientific Article in Journal of Virology J. Virol. 82, 6721-6733 (2008)
Molecular basis of cytotoxicity of Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in EBV latency III B cells: LMP1 induces type II ligand-independent autoactivation of CD95/Fas with caspase 8-mediated apoptosis.
2008 Scientific Article in Development / Company of Biologists Development 135, 2757-2765 (2008)
Conditional ablation of Notch signaling in pancreatic development.
2008 Scientific Article in Hepatology Hepatology 48, 607-616 (2008)
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.
2008 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 7, 282-289 (2008)
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins.
2008 Scientific Article in PLoS ONE PLoS ONE 3:e1996 (2008)
Restricted expression of Epstein-Barr virus latent genes in murine B cells derived from embryonic stem cells.
2008 Scientific Article in Virology Virology 371, 246-256 (2008)
The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus.
2008 Scientific Article in PLoS ONE PLoS ONE 3:e1464 (2008)
Conditional immortalization of human B cells by CD40 ligation.
2008 Scientific Article in Journal of Virology J. Virol. 82, 5693-5702 (2008)
The affinity of EBNA1 for its origin of DNA synthesis is a determinant of the origin's replicative efficiency.
2008 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 36:e83 (2008)
Conditional gene vectors regulated in cis.
2008 Scientific Article in Oncogene Oncogene 27, 4592-4602 (2008)
Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC.
2008 Scientific Article in Journal of Cell Biology, The J. Cell Biol. 182, 117-127 (2008)
Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease.
2008 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 205, 1317-1329 (2008)
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.
2008 Scientific Article in Clinical and Experimental Metastasis Clin. Exp. Metastasis 25, 679-683 (2008)
Precise measurement of the E-cadherin repressor Snail in formalin-fixed endometrial carcinoma using protein lysate microarrays.
2008 Scientific Article in Cells Tissues Organs Cells Tissues Organs 188, 91-102 (2008)
Notch signaling in embryonic and adult myelopoiesis.
2008 Scientific Article in Journal of Plankton Research J. Plankton Res. 30, 587-606 (2008)
Use of fluorescence information for automated phytoplankton investigation by image analysis.
2008 Scientific Article in Molecular Immunology Mol. Immunol. 45, 3230-3237 (2008)
Role of STAT3 in glucocorticoid-induced expression of the human IL-10 gene.
2008 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 105, 1692-1697 (2008)
Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins.
2008 Scientific Article in Progress in Histochemistry and Cytochemistry Prog. Histochem. Cytochem. 42, 203-252 (2008)
Modern techniques for the diagnostic evaluation of the trephine bone marrow biopsy: Methodological aspects and applications.
2008 Scientific Article in Blood Blood 111, 1448-1455 (2008)
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1.
2008 Scientific Article in Anatomia, Histologia, Embryologia Anat. Histol. Embryol. 37, 205-213 (2008)
Stereological characteristics of the equine accessory nerve.
2008 Scientific Article in Modern Pathology Mod. Pathol. 21, 544-552 (2008)
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer.
2008 Scientific Article in Briefings in Bioinformatics Brief. Bioinform. 9, 129-143 (2008)
Classification of mass-spectrometric data in clinical proteomics using learning vector quantization methods.
2008 Scientific Article in Cancer Research Cancer Res. 68, 707-714 (2008)
Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations.
2008 Scientific Article in PLoS Genetics PLoS Genet. 4:e7 (2008)
ER stress-mediated apoptosis in a new mouse model of Osteogenesis imperfecta.
2008 Scientific Article in Haematologica - The Hematology Journal Haematologica 93, 623-626 (2008)
Primary extramedullary plasmacytoma: Similarities with and differences from multiple myeloma revealed by interphase cytogenetics.
2008 Scientific Article in Leukemia Research Leuk. Res. 32, 79-88 (2008)
Cyclin D1 positive multiple myeloma: Predominance of the short, 3'UTR-deficient transcript is associated with high cyclin D1 mRNA levels in cases with t(11;14) translocation, but does not correlate with proliferation rate or genomic deletions.
2008 Scientific Article in PLoS Biology PLoS Biol. 6, 86-98:e8 (2008)
The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity.
2008 Scientific Article in Experimental Cell Research Exp. Cell Res. 314, 153-163 (2008)
Deletion of exon 8 increases cisplatin-induced E-cadherin cleavage.
München, Ludwig-Maximilians-Universität München, Fakultät für Biologie, Diss., 2007, 150 S.
Rolle des Chromatin-Proteins HMGA1a für die Definition von Replikationsursprüngen.
München, Ludwig-Maximilians-Universität München, Fakultät für Biologie, Diss., 2007, 103 S.
Latent Epstein-Barr virus infection and the germinal center reaction.
2007 Review in Signal Transduction: Receptors, Mediators and Genes Signal Transduct. 7, 20-33 (2007)
Signal transduction by the Epstein-Barr virus oncogene latent membrane protein 1 (LMP1).
2007 Scientific Article in Signal Transduction: Receptors, Mediators and Genes Signal Transduct. 7, 3-4 (2007)
Signal transduction by viral factors: Critical interface between the virus and ist host cell with implications for the viral life cycle and disease development.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2007, 112 S.
Rolle des Epstein-Barr Virus Proteins LMP2A in transformierten B-Zellen.
München, Technische Universität, Fakultät für Medizin, Diss., 2007, 148 S.
Serologische Identifizierung und Charakterisierung von Tumorantigenen eines Neuroblastoms Stadium 3 ohne MYCN-Genamplifikatio.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2007, 157 S.
Untersuchung molekularer Mechanismen der EBNA-2 vermittelten Transaktivierung.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2007, 110 S.
Molekulare Mechanismen der Induktion von Interleukin-10 durch Glukokortikoide.
2007 Review in Cancer Genomics & Proteomics Cancer Genomics Proteomics 4, 349-358 (2007)
Molecular profiling for the identification of new biomarkers in smokers and cancer patients.
2007 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 56, 1645-1652 (2007)
Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition.
2007 Scientific Article in Apoptosis Apoptosis 12, 1927-1943 (2007)
Nicotine and apoptosis.
2007 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 56, 1645-1652 (2007)
Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition.
2007 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 56, 1429-1442 (2007)
Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment.
2007 Scientific Article in Cancer Research Cancer Res. 67, 8865-8873 (2007)
Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma.
In: Krebsimmuntherapien. Köln: Deutscher Ärzte-Verl., 2007. 175-182
Kopf-Hals-Tumoren.
2007 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 104, 10000-10005 (2007)
Global distribution of negative cofactor 2 subunit-alpha on human promoters.
2007 Scientific Article in Oncogene Oncogene 26, 4987-4998 (2007)
Inhibition of IL-6-dependent growth of myeloma cells by an acidic peptide repressing the gp130-mediated activation of Src family kinases.
2007 Scientific Article in Journal of Virology J. Virol. 81, 10092-10100 (2007)
Epstein-Barr virus exploits BSAP/Pax5 to achieve the B-cell specificity of its growth-transforming program.
2007 Scientific Article in Human Immunology Hum. Immunol. 68, 75-85 (2007)
Activated B cells mediate efficient expansion of rare antigen-specific T cells.
2007 Scientific Article in Biological Chemistry Biol. Chem. 388, 1083-1090 (2007)
B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance.
2007 Scientific Article in Blood Blood 110, 3715-3721 (2007)
Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2007, 128 S.
Die Rolle der Epstein-Barr Virus nukleären Antigene 3A und 3C in der B-Zellimmortalisierung.
2007 Scientific Article in Journal of Virology J. Virol. 81, 2274-2282 (2007)
EBNA2 Interferes with the Germinal Center Phenotype by Downregulating BCL6 and TCL1 in Non-Hodgkin's Lymphoma Cells.
2007 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 204, 331-343 (2007)
Hierarchy of notch-delta interactions promoting T cell lineage commitment and maturation.
2007 Scientific Article in Developmental Dynamics Dev. Dyn. 236, 282-289 (2007)
Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.
2007 Scientific Article in Oncogene Oncogene 26, 1789-1801 (2007)
Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination.
2006 Scientific Article in Molecular and Cellular Biology Mol. Cell. Biol. 26, 5270-5283 (2006)
Differential binding of replication proteins across the human c-myc replicator.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2006, 137 S.
Etablierung einer optimierten Helferzelllinie zum Genvektortransfer in humane B-Zellen.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2006, 127 S.
Functional characterization of the 40 bp internal repeat of murine gamma herpesvirus-68.
2006 Scientific Article in Anticancer Research Anticancer Res. 26, 153-158 (2006)
Limited suitability of EpCAM for molecular staging of tumor borders in head and neck cancer.
2006 Scientific Article in Vaccine Vaccine 24, 4595-4597 (2006)
Comparison of the immunological memory after DNA vaccination and protein vaccination against anthrax in sheep.
2006 Scientific Article in Journal of Virology J. Virol. 80, 8133-8144 (2006)
Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJk-dependent pathway.
2006 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 103, 14188-14193 (2006)
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes.
2006 Scientific Article in Journal of General Virology J. Gen. Virol. 87, 3169-3176 (2006)
The CR4 region of EBNA2 convers viability of Epstein-Barr virus-transformed B cells by CBF1-independent signalling.
2006 Scientific Article in Molecular and Cellular Biology Mol. Cell. Biol. 26, 7731-7746 (2006)
Identification of new human origins of DNA replication by an origin-trapping assay.
2006 Scientific Article in Gene Therapy Gene Ther. 13, 844-856 (2006)
Genetic design of an optimized packaging cell line for gene vectors transducing human B cells.
2006 Scientific Article in Journal of Pathology, The J. Pathol. 209, 430-435 (2006)
The antibody 2B4 directed against the Epstein-Barr virus (EBV)-encoded nuclear antigen I (EBNA I) detects MAGE-4: Implications for studies on the EBV association of human cancers.
2006 Scientific Article in Journal of Virology J. Virol. 80, 9761-9771 (2006)
Cellular target genes of Epstein-Barr virus nuclear antigen 2.
2006 Scientific Article in Inhalation Toxicology Inhal. Toxicol. 18, 733-740 (2006)
Distribution pattern of inhaled ultrafine gold particles in the rat lung.
2006 Scientific Article in Blood Blood 107, 4433-4439 (2006)
Epstein-Barr virus nuclear antigen 2 induces FcRH5 expression through CBF1.
2006 Scientific Article in Gene Therapy Gene Ther. 13, 150-162 (2006)
Epstein-Barr virus vector-mediated gene transfer into human B cells: Potential for antitumor vaccination.
2005 Scientific Article in PLoS Biology PLoS Biol. 3, 2148-2157:e404 (2005)
Epstein-Barr Virus provides a new paradigm: A requirement for the immediate inhibition of apoptosis.
2005 Scientific Article in EMBO Journal, The EMBO J. 24, 1406-1417 (2005)
Cell cycle regulation of chromatin at an origin of DNA replication.
2005 Scientific Article in Blood Blood 106, 4339-4344 (2005)
Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus.
In: Robertson, E.S.* [Eds.]: Epstein-Barr Virus. Norwich: Caister Acad. Press, 2005. 463-499
EBNA-2 and Notch Signalling.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2005, 148 S.
Die Diversität Cytomegalovirus-spezifischer T-Zellen nach Selektion mittels B-Zell-Vektoren.
2005 Scientific Article in European Journal of Immunology Eur. J. Immunol. 35, 2250-2258 (2005)
HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy.
2005 Scientific Article in Journal of Virology J. Virol. 79, 10709-10717 (2005)
Epstein-barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A,-3B and -3C expression in burkitt's lymphoma cells and with increased resistance to apoptosis.
2005 Scientific Article in European Journal of Immunology Eur. J. Immunol. 35, 2110-2121 (2005)
Selection of CMC-specific CD8⁺ and CD4⁺ T cells by mini-EBV-transformed B cell lines.
2005 Scientific Article in Blood Blood 105, 3263-3269 (2005)
EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX.
2005 Scientific Article in Journal of Virology J. Virol. 79, 8784-8792 (2005)
A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent.
2005 Scientific Article in Journal of Immunology J. Immunol. 174, 6672-6676 (2005)
Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation.
2005 Scientific Article in Blood Blood 105, 1632-1639 (2005)
Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells.
2004 Scientific Article in Journal of Virology J. Virol. 78, 12694-12697 (2004)
EBNA2 is required for protection of latently Epstein-Barr virus-infected B cells against specific apoptotic stimuli.
2004 Scientific Article in Trends in Molecular Medicine Trends Mol. Med. 10, 331-336 (2004)
Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease.
2004 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 199, 1409-1420 (2004)
CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1.
2004 Scientific Article in Gene Gene 343, 91-97 (2004)
Efficient somatic gene targeting in the lymphoid human cell I DG75.
2004 Scientific Article in Anticancer Research Anticancer Res. 24, 3715-3721 (2004)
Targeted gene expression using a 1.1 kilobase promoter fragment of the tumour-associated antigen EpCAM.
München, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, Diss., 2004, 105 S.
Expansion von T-Zellen seltener Spezifität mittels B-Zellen.
2004 Scientific Article in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 61, 1198-1207 (2004)
Profile identification of disease-associated humoral antigens using AMIDA, a novel proteomics-based technology.
2004 Scientific Article in European Journal of Immunology Eur. J. Immunol. 34, 2500-2509 (2004)
Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells.
2004 Scientific Article in Journal of General Virology J. Gen. Virol. 85, 2347-2356 (2004)
Active NF-kB signalling is a prerequisite for influenza virus infection.
2004 Scientific Article in Journal of Virology J. Virol. 78, 3941-3952 (2004)
Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: Activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary b cells by EBV.
2004 Scientific Article in Journal of Virology J. Virol. 78, 2-13 (2004)
Functional analysis of Epstein-Barr virus SM protein: Identification of amino acids essential for structure, transactivation, splicing inhibition and virion production.
München, Ludwig-Maximilians-Universität, Diss., 2003, 125 S.
Identifizierung und Charakterisierung von Zielgenen des Epstein-Barr Virus nukleären Antigens 2 (EBNA2).
2003 Scientific Article in International Journal of Immunopathology and Pharmacology Int. J. Immunopathol. Pharmacol. 16, 41-48 (2003)
Immune restoration in head and neck cancer patients via cyclooxygenase inhibition: An update.
2003 Scientific Article in FASEB Journal FASEB J. 17, 286-288 (2003)
Impaired monocyte function in cancer patients: restoration with a cyclooxygenase-2 inhibitor.
2002 Scientific Article in HNO HNO 50, 1075-1078 (2002)
Der Madelung-Fetthals.
2001 Scientific Article in Anticancer Research Anticancer Res. 21, 3499-3503 (2001)
TNFalpha contributes to the antitumor activity of a bispecific, trifunctional antibody.
2001 Scientific Article in Cancer Cytopathology Cancer Cytopathol. 92, 620-628 (2001)
Tumor necrosis factor alpha negatively regulates the expression of the carcinoma-associated antigen epithelial cell adhesion molecule.
2001 Scientific Article in Laryngo-Rhino-Otologie Laryngol. Rhinol. Otol. 80, 191-195 (2001)
IL-2 Gentherapie bei HNO-Karzinomen.
2000 Scientific Article in FASEB Journal FASEB J. 14, 661-668 (2000)
Tumor cell-derived prostaglandin E2 inhibits monocyte function by interfering with CCR5 and Mac-1.
1999 Scientific Article in Anticancer Research Anticancer Res. 19, 2237-2242 (1999)
Ep-CAM - a marker for the detection of disseminated tumor cells in patients suffering from SCCHN.
1999 Scientific Article in Human Gene Therapy. Clinical Development Hum. Gene Ther. 10, 141-147 (1999)
Gene therapy--phase I trial for primary untreated head and neck squamous cell cancer (HNSCC) UICC stage II-IV with a single intratumoral injection of hIL-2 plasmids formulated in DOTMA/Chol.
1999 Scientific Article in JAMA Otolaryngology - Head & Neck Surgery Arch. Otolaryngol. Head Neck Surg. 125, 82-88 (1999)
Impairment of T-cell activation in head and neck cancer in situ and in vitro: strategies for an immune restoration.
1999 Scientific Article in Anticancer Research Anticancer Res. 19, 5335-5339 (1999)
Targeting head and neck cancer by GM-CSF-mediated gene therapy in vitro.
1999 Scientific Article in Laryngo-Rhino-Otologie Laryngol. Rhinol. Otol. 78, 36-40 (1999)
Induktion einer antitumoralen Immunantwort im Mausmodell nach Vakzinierung mit B7.1 exprimierenden Tumorzellen.
1998 Scientific Article in International Journal of Cancer Int. J. Cancer 75, 620-625 (1998)
Apoptosis in burkitt lymphoma cells is prevented by promotion of cysteine uptake.
1998 Scientific Article in International Journal of Molecular Medicine Int. J. Mol. Med. 2, 167-171 (1998)
Lack of B7.1 and B7.2 on head and neck cancer cells and possible significance for gene therapy.
1997 Scientific Article in European Archives of Oto-Rhino-Laryngology and Head & Neck Eur. Arch. Otorhinolaryngol. 254, S130-S132 (1997)
In vitro studies of liposome-mediated gene transfer into head and neck cancer cell lines.
1997 Scientific Article in Laryngo-Rhino-Otologie Laryngol. Rhinol. Otol. 76, 411-414 (1997)
Rezeptor-mediierter Gentransfer in Plattenepithelkarzinome des Kopf-Hals-Bereiches.
1996 Scientific Article in International Journal of Cancer Int. J. Cancer 68, 577-582 (1996)
Mosaicism of bcr/abl protein expression in B-cells in CML.
1993 Scientific Article in Journal of Virology J. Virol. 67, 1292-1299 (1993)
Episomal and Integrated Copies of Epstein-Barr Virus Coexist in Burkitt Lymphoma Cell Lines.
1993 Scientific Article in Experimental Hematology Exp. Hematol. 21, 74-79 (1993)
Characterization of Hemopoietic Cell Populations from Human Cord Blood Expressing c-kit.
In: Turesz, T.* [Eds.]: Proceedings (Proc. of the 5th Intern. Symp. on EBV and Associated Disesases, Annecy, Frankreich, 13.-19. Sept. 1992). Montrouge, Frankreich: John Libbey Eurotext, 1993. 159-164 ( ; 225)
The Epstein-Barr Nuclear Antigen 2 (EBNA2) Transactivates the Terminal Protein 1 Gene by Interacting with a Cis-Element Located in the Promoter Region.
1993 Scientific Article in Journal of Virology J. Virol. 67, 4237-4245 (1993)
Cis-acting Elements in the Lytic Origin of DNA Replication of Epstein-Barr Virus.
In: Tursz, T.* [Eds.]: The Epstein-Barr Virus and Associated Diseases. Montrouge, Frankreich: John Libbey Eorotext, 1993. 245-252 ( ; 225)
Integration of EBV and MDV in B- and T-cell Lymphomas.
In: Tursz, T.* [Eds.]: Proceedings (The Epstein-Barr Virus and Associated Diseases, Annecy, Frankreich, 13.-19. Sept. 1992). Montrouge, Frankreich: John Libbey Eurotext, 1993. 211-217 ( ; 225)
Delineation of the Cis-Acting Sequence Mediating Transactivation of a bi-Directional Latent Promoter Region by Epstein-Barr Virus Nuclear Antigen 2 (EBNA2).
In: Tursz, T.* [Eds.]: The Epstein-Barr Virus and Associated Diseases. Montrouge, Frankreich: John Libbey Eurotext, 1993. 83-88 ( ; 225)
Expression of EBNA2 as a Conditional Mutant.
1993 Scientific Article in Virus Research Virus Res. 27, 55-69 (1993)
Expression of the Epstein-Barr Virus (EBV) Latent Membrane Protein is Tightly regulated, Independently of EB Nuclear Antigen 2 and of EBV Integration or Copy Number.
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Irradiated Human Fibroblasts Substitute for Epstein-Barr Virus in Stimulating the Clonogenicity of Burkitt Lymphoma Cells.
1993 Scientific Article in EMBO Journal, The EMBO J. 12, 3921-3929 (1993)
A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus.
1993 Scientific Article in Oncogene Oncogene 8, 1099-1102 (1993)
Early down-regulation of c-myc in dimethylsulfoxide-induced mouse erythroleukemia (MEL) cells is mediated at the P1/P2 promoters.
1993 Scientific Article in Experimental Hematology Exp. Hematol. 21, 74-79 (1993)
Characterization of hemopoietic cell populations from human cord blood expressing c-kit.
1993 Scientific Article in EMBO Journal, The EMBO J. 12, 3277-3286 (1993)
Latent Marek's disease virus can be activated from its chromosomally integrated state in herpesvirus-transformed lymphoma cells.
1991 Scientific Article in Seminars in Virology Semin. Virol. 2 (1991)
Herpesviral DNA replication: between the known and unknown.
1990 Scientific Article in Current Topics in Microbiology and Immunology Curr. Top. Microbiol. Immunol. 166, 359-366 (1990)