Publications TMO
2022 Scientific Article in Oncology Oncology 101, 126-133 (2022)
MALDI mass spectrometry imaging-Diagnostic pathways and metabolites for renal tumor entities.
2022 Scientific Article in Cancers Cancers 14:5485 (2022)
T cells directed against the metastatic driver chondromodulin-1 in ewing sarcoma: Comparative engineering with CRISPR/Cas9 vs. retroviral gene transfer for adoptive transfer.
2022 Scientific Article in JCI insight JCI insight 7:e162138 (2022)
Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:889836 (2022)
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.
2022 Scientific Article in Oncology Research and Treatment Oncol. Res. Treat. 45, 2, 162-162 (2022)
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
2022 Scientific Article in PNAS Nexus PNAS Nexus 1:pgac045 (2022)
Quantitation of SARS-CoV-2 neutralizing antibodies with a virus-free, authentic test.
2022 Scientific Article in Nature Communications Nat. Commun. 13:4689 (2022)
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:913275 (2022)
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
2022 Review in Frontiers in Microbiology Front. Microbiol. 13:955603 (2022)
Strategies of Epstein-Barr virus to evade innate antiviral immunity of its human host.
2022 Scientific Article in PLoS ONE PLoS ONE 17:e0271630 (2022)
Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2200512119 (2022)
EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus-infected B cells.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 66:101616 (2022)
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5104 (2022)
A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.
2022 Nature Communications Nat. Commun. 13:6009 (2022)
Author Correction: A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity (Nature Communications, (2022), 13, 1, (5104), 10.1038/s41467-022-32507-6).
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1071-1083 (2022)
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
2022 Scientific Article in EBioMedicine EBioMedicine 85:104296 (2022)
The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling.
2022 Scientific Article in European Journal of Cancer Eur. J. Cancer 176, 41-49 (2022)
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.
2022 Scientific Article in Cancers Cancers 14:3745 (2022)
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.
2022 Scientific Article in Laboratory Investigation Lab. Invest. 102, 1400-1405 (2022)
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.
2022 Scientific Article in International Journal of Biological Sciences Int. J. Biol. Sci. 18, 5230-5240 (2022)
Inhibition of APOE potentiates immune checkpoint therapy for cancer.
2022 Scientific Article in Biomedicines Biomedicines 10:825 (2022)
A novel anti-CD73 antibody that selectively inhibits membrane 2 CD73 shows antitumor activity and induces tumor immune escape.
2022 Scientific Article in Leukemia Leukemia 36, 2281–2292 (2022)
PARP14 is a novel target in STAT6 mutant follicular lymphoma.
2022 Scientific Article in Cancers Cancers 14:1763 (2022)
MALDI mass spectrometry imaging—prognostic pathways and metabolites for renal cell carcinomas.
2022 Scientific Article in Histochemistry and Cell Biology Histochem. Cell Biol. 157, 595–605 (2022)
A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS.
2022 Scientific Article in BMC Cancer BMC Cancer 22:254 (2022)
Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF.
2022 Scientific Article in Cancer Cell Cancer Cell 40, 639-655.e13 (2022)
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.
2022 Scientific Article in Annals of Translational Medicine Ann. Transl. Med. 10:625 (2022)
A 3D multi-modal intelligent intervention system using electromagnetic navigation for real-time positioning and ultrasound images: A prospective randomized controlled trial.
2022 Scientific Article in Cancer communications Cancer Comm. 42, 517-535 (2022)
Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients.
2022 Scientific Article in Journal of Enzyme Inhibition and Medicinal Chemistry J. Enzyme Inhib. Med. Chem. 37, 592-596 (2022)
First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors.
2022 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 12:e666 (2022)
The synergism of spatial metabolomics and morphometry improves machine learning-based renal tumour subtype classification.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1589 (2022)
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19.
2022 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 117:11 (2022)
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 473-486.e9 (2022)
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 2865-2877 (2022)
Spatial metabolomics identifies distinct tumor-specific subtypes in gastric cancer patients.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 329-345.e8 (2022)
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 1038-1052 (2022)
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2022 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 50, 490-511 (2022)
Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1.
2022 Scientific Article in Journal of Pathology, The J. Pathol. 256, 202-213 (2022)
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients.
In: (European Conference on Biomedical Optics, 20–24 June 2021, Munich Germany). 2021. DOI: 10.1117/12.2615998 ( ; 11923)
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.
2021 Scientific Article in mBio mBio 12:e0224321 (2021)
The Epstein-Barr virus oncogene EBNA1 suppresses natural killer cell responses and apoptosis early after infection of peripheral B cells.
2021 Scientific Article in PLoS Genetics PLoS Genet. 17:e1009951 (2021)
MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells.
2021 Review in Frontiers in Oncology Front. Oncol. 11:771335 (2021)
Various uses of PD1/PD-L1 inhibitor in oncology: Opportunities and challenges.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:796379 (2021)
Immunoinformatic analysis reveals antigenic heterogeneity of Epstein-Barr virus is immune-driven.
2021 Scientific Article in British Journal of Haematology Br. J. Haematol., DOI: 10.1111/bjh.17990 (2021)
The molecular ontogeny of follicular lymphoma: Gene mutations succeeding the BCL2 translocation define common precursor cells.
2021 Scientific Article in EJNMMI Research EJNMMI Res. 11:120 (2021)
Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma.
2021 Scientific Article in Cellular Microbiology Cell. Microbiol. 23:e13399 (2021)
Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.
2021 Scientific Article in Cell Discovery Cell Discov. 7:105 (2021)
Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV.
2021 Scientific Article in Physics & Imaging in Radiation Oncology Phys. Imag. Radiat. Oncology 20, 11-16 (2021)
In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice.
2021 Scientific Article in EMBO Reports EMBO Rep.:e53007 (2021)
PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.
2021 Scientific Article in Cancer Research Cancer Res. 81, 5862-5875 (2021)
Patterns of carbon-bound exogenous compounds in lung cancer patients and association with disease pathophysiology.
2021 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 49, 10657–10676 (2021)
Modulation of alternative splicing during early infection of human primary B lymphocytes with Epstein-Barr virus (EBV): A novel function for the viral EBNA-LP protein.
2021 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 11:e547 (2021)
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101330 (2021)
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1202-1216 (2021)
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 13:e13490 (2021)
Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101334 (2021)
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
2021 Scientific Article in Cell Death & Disease Cell Death Dis. 12:723 (2021)
Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma.
2021 Scientific Article in Molecular Immunology Mol. Immunol. 138, 128-136 (2021)
Context-dependent regulation of immunoglobulin mutagenesis by p53.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1685-1700.e9 (2021)
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
2021 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 185, 179-191 (2021)
Mass spectrometry imaging identifies metabolic patterns associated with malignant potential in pheochromocytoma and paraganglioma.
2021 Scientific Article in Science Signaling Sci. Signal. 14:eabc1648 (2021)
ERK phosphorylation is RAF independent in naïve and activated B cells but RAF dependent in plasma cell differentiation.
2021 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 413, 5619-5632 (2021)
Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA).
2021 Scientific Article in Nature Communications Nat. Commun. 12:2999 (2021)
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
2021 Scientific Article in Diabetologia Diabetologia 64, 1850-1865 (2021)
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
2021 Scientific Article in Photoacoustics Photoacoustics 22:100263 (2021)
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.
2021 Scientific Article in Blood Blood 137, 3225-3236 (2021)
CD27 is required for protective lytic EBV antigen specific CD8+ T cell expansion.
2021 Scientific Article in Frontiers in Oncology Front. Oncol. 11:612354 (2021)
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.
2021 Scientific Article in Journal of Clinical Oncology - JCO J. Clin. Oncol. 39, 1468-1478 (2021)
HER2 expression, test deviations, and their impact on survival in metastatic gastric cancer: Results from the prospective multicenter VARIANZ study.
2021 Scientific Article in Chemosphere Chemosphere 276:130143 (2021)
Characteristics of chemical profile, sources and PAH toxicity of PM2.5 in beijing in autumn-winter transit season with regard to domestic heating, pollution control measures and meteorology.
2021 Scientific Article in Advanced healthcare materials Adv. Healthc. Mater. 10:e2002115 (2021)
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.
2021 Nature Nature 592:E1 (2021)
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 28, 213-224 (2021)
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.
2021 Scientific Article in Journal of Hepatology J. Hepatol. 75, 74-85 (2021)
Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection.
2021 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 49, 3217-3241 (2021)
Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation.
2021 Scientific Article in eLife eLife 10:e62161 (2021)
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.
2021 Scientific Article in PLoS Pathogens PLoS Pathog. 17:e1009117 (2021)
Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1111 (2021)
Notch2-mediated plasticity between marginal zone and follicular B cells.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0248594 (2021)
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.
2021 Scientific Article in mBio mBio 12:e03440-20 (2021)
Multiple viral micrornas regulate interferon release and signaling early during infection with epstein-barr virus.
2021 Scientific Article in Frontiers in Oncology Front. Oncol. 10:614876 (2021)
PD-1 blockade aggravates Epstein–Barr Virus+ post-transplant lymphoproliferative disorder in humanized mice resulting in central nervous system involvement and CD4+ T cell dysregulations.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 45:101147 (2021)
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.
2021 Scientific Article in Nature Nature 590, 326–331 (2021)
Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000898 (2021)
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 833-844.e5 (2021)
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.
2021 Scientific Article in Molecular Oncology Mol. Oncol. 15, 1040-1053 (2021)
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.
2021 Scientific Article in Breast Care Breast Care 16, 523-531 (2021)
PITX2 DNA-methylation: Predictive versus prognostic value for anthracycline-based chemotherapy in triple-negative breast cancer patients.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000924 (2021)
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.
2021 Scientific Article in European Radiology Eur. Radiol. 31, 4175–4183 (2021)
Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 23, 195-207 (2021)
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice.
2021 Scientific Article in Infection - A Journal of Infectious Disease Infection 49, 63–73 (2021)
First results of the "Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)".
2021 Scientific Article in International Journal of Radiation Oncology, Biology, Physics Int. J. Radiat. Oncol. Biol. Phys. 109, 76-83 (2021)
Normal tissue response of combined temporal and spatial fractionation in proton minibeam radiation therapy.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0243462 (2020)
A practical guide to unbiased quantitative morphological analyses of the gills of rainbow trout (Oncorhynchus mykiss) in ecotoxicological studies.
2020 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 8:570305 (2020)
Circ-ZDHHC5 accelerates esophageal squamous cell carcinoma progression in vitro via miR-217/ZEB1 axis.
2020 Scientific Article in European Urology Open Science Eu. Urol. Open Sci. 22, 88-96 (2020)
In situ metabolomics expands the spectrum of renal tumours positive on 99mTc-sestamibi single photon emission computed tomography/computed tomography examination.
2020 Scientific Article in Hypertension Hypertension 76, 1769-1777 (2020)
Effect of dietary sodium modulation on pig adrenal steroidogenesis and transcriptome profiles.
2020 Review in Frontiers in Oncology Front. Oncol. 10:575037 (2020)
Emerging landscapes of tumor immunity and metabolism.
2020 Review in Animal reproduction Anim. Reprod. 17:e20200064 (2020)
A decade of experience with genetically tailored pig models for diabetes and metabolic research.
2020 Scientific Article in Biomarker Research Biomark. Res. 8:46 (2020)
Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL.
2020 Scientific Article in Communications Biology Comm. Biol. 3:628 (2020)
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
2020 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:6832 (2020)
Chronic occupational exposure to ionizing radiation induces alterations in the structure and metabolism of the heart: A proteomic analysis of human formalin-fixed paraffin-embedded (FFPE) cardiac tissue.
2020 Scientific Article in Analytica Chimica Acta Anal. Chim. Acta 1134, 125-135 (2020)
Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS.
2020 Scientific Article in Molecular Therapy-Oncolytics Mol. Ther.-Oncolytics 18, 504-524 (2020)
CAR-T cells targeting Epstein-Barr virus gp350 validated in a humanized mouse model of EBV infection and lymphoproliferative disease.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:14461 (2020)
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.
2020 Scientific Article in American Journal of Cancer Research Am. J. Cancer Res. 10, 1785-1792 (2020)
High levels of KLK7 protein expression are related to a favorable prognosis in triple-negative breast cancer patients.
2020 Other: Opinion in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 8, 733-734 (2020)
A multi-test strategy for adrenal tumours.
2020 Scientific Article in Angewandte Chemie - Internationale Edition Angew. Chem.-Int. Edit. 132, 17600-17603 (2020)
Morphometric cell classification for single-Cell MALDI-mass spectrometry imaging.
2020 Scientific Article in Journal of Translational Medicine J. Transl. Med. 18:242 (2020)
Evaluation of T-activated proteins as recall antigens to monitor Epstein-Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting.
2020 Scientific Article in Nature Communications Nat. Commun. 11:3068 (2020)
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.
2020 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 117, 12961-12968 (2020)
Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells.
2020 Nature Communications Nat. Commun. 11:3058 (2020)
Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity (Nature Communications, (2019), 10, 1, (3274), 10.1038/s41467-019-11104-0).
2020 Scientific Article in ChemBioChem ChemBioChem 21, 2495-2502 (2020)
Mapping of the binding interface of PET tracer molecules and Alzheimer Disease Aβ fibrils using MAS solid-state NMR spectroscopy.
2020 Scientific Article in Transplant Immunology Transpl. Immunol. 61:101291 (2020)
Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors.
2020 Review in Hormone and Metabolic Research Horm. Metab. Res. 52, 435-447 (2020)
In situ metabolite mass spectrometry imaging: New insights into the adrenal gland.
2020 Scientific Article in Journal of Virology J. Virol. 94:e00284-20 (2020)
The Epstein-Barr virus major tegument protein BNRF1 is a common target of cytotoxic CD4+ T cells.
2020 Scientific Article in Frontiers in Oncology Front. Oncol. 10:494 (2020)
The intratumoral heterogeneity reflects the intertumoral subtypes of glioblastoma multiforme: A regional immunohistochemistry analysis.
2020 Scientific Article in Molecular Oncology Mol. Oncol. 14, 1653-1669 (2020)
Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100953 (2020)
De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry.
2020 Scientific Article in Cell Reports Cell Rep. 31:107522 (2020)
Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma.
2020 Scientific Article in Gut (eGut) Gut 69, 1939-1951 (2020)
Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn's disease recurrence.
2020 Nature metabolism Nat. Metab. 2, 380 (2020)
Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission (Nature Metabolism, (2020), 2, 2, (192-209), 10.1038/s42255-020-0171-3).
2020 Scientific Article in Clinical and translational immunology Clin. Transl. Immunology 9:e1117 (2020)
Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: Results of a phase I trial.
2020 Review in Seminars in Immunopathology Semin. Immunopathol. 42, 131-142 (2020)
Epigenetic lifestyle of Epstein-Barr virus.
2020 Scientific Article in Journal of the American Geriatrics Society J. Am. Geriatr. Soc. 68, 940-942 (2020)
China's oldest coronavirus survivors.
2020 Scientific Article in Cell Death & Disease Cell Death Dis. 11:192 (2020)
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction.
2020 Scientific Article in Hypertension Hypertension 75, 634-644 (2020)
Mass spectrometry imaging establishes 2 distinct metabolic phenotypes of aldosterone-producing cell clusters in primary aldosteronism.
2020 Scientific Article in Nature Communications Nat. Commun. 11:685 (2020)
A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation.
2020 Scientific Article in Journal of Virology J. Virol. 94:e01918-19 (2020)
Identification and cloning of a new western Epstein-Barr virus strain that replicates efficiently in primary B cells.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100978 (2020)
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:79 (2020)
Mass Spectrometry imaging of atherosclerosis-affine Gadofluorine following Magnetic Resonance imaging.
2020 Scientific Article in Journal of General Virology J. Gen. Virol. 101, 284-289 (2020)
Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-Herpesviruses provides a signature o virus-specific signalling.
2020 Scientific Article in Radiation Oncology Radiat. Oncol. 15:7 (2020)
Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".
2020 Review in Cell and Tissue Research Cell Tissue Res. 380, 341-378 (2020)
Porcine models for studying complications and organ crosstalk in diabetes mellitus.
2020 Scientific Article in Nature metabolism Nat. Metab. 2, 192-209 (2020)
Targeted pharmacological therapy restores β-cell function for diabetes remission.
2020 Scientific Article in Growth Hormone and IGF Research Growth Horm. IGF Res. 51, 6-16 (2020)
Linkage between growth retardation and pituitary cell morphology in a dystrophin-deficient pig model of Duchenne muscular dystrophy.
2020 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 11, 226-240 (2020)
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction.
2020 Scientific Article in Radiation and Environmental Biophysics Radiat. Environ. Biophys. 59, 111-120 (2020)
A proof of principle experiment for microbeam radiation therapy at the Munich compact light source.
2020 Scientific Article in Haematologica - The Hematology Journal Haematologica 105, 937-950 (2020)
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.
In: Fundamentals and Applications of Fourier Transform Mass Spectrometry. 2019. 253-279
In situ metabolomics in cancer tissue by high-resolution mass spectrometry imaging.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:19483 (2019)
Dusp8 affects hippocampal size and behavior in mice and humans.
2019 Scientific Article in Journal of Molecular Biology J. Mol. Biol. 431, 4910-4921 (2019)
Biochemical and structural insights into Carbonic Anhydrase XII/Fab6A10 complex.
2019 Scientific Article in Cell Cell 179, 1661-1676 (2019)
Deep learning reveals cancer metastasis and therapeutic antibody targeting in entire body.
2019 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 20:2103 (2019)
Combined treatment with low-dose ionizing radiation and ketamine induces adverse changes in CA1 neuronal structure in murine hippocampi.
2019 Scientific Article in Nature Nature 576, 287-292 (2019)
Patch repair of deep wounds by mobilized fascia.
2019 Scientific Article in Small Small 15:1904112 (2019)
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.
2019 Scientific Article in Nature metabolism Nat. Metab. 1, 1009-1026 (2019)
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 130-130 (2019)
Targets of the T cell response to human herpesvirus 6B.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 99-100 (2019)
The T cell epitope repertoire of polyomavirus BK.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 85-85 (2019)
B-Raf and Raf-1 are dispensable for activation of the MAPK/Erk signaling pathway in murine B cells but contribute to plasma cell differentiation.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 112-112 (2019)
The antigen-specific T-cell receptor repertoire against human cytomegalovirus.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 25-26 (2019)
"Two B or not two B?" The potency of Nntch2 in follicular vs marginal zone B cell identity.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 69-70 (2019)
Type-I interferon regulates ghrelin-levels leading to anorexia and weight loss while promoting inflammatory immune responses.
2019 Meeting abstract in Bone Marrow Transplantation Bone Marrow Transplant. 54, 177-178 (2019)
Single cell identification of defined ebv epitope-specific TCR alpha beta pairs for adoptive T cell transfer against EBV infection and EBV-associated malignancies.
2019 Scientific Article in Pathogens Pathogens 8:177 (2019)
Proliferative kidney disease and proliferative darkening syndrome are linked with brown trout (Salmo trutta fario) mortalities in the pre-alpine Isar River.
2019 Scientific Article in mBio mBio 10:e01723-19 (2019)
First days in the life of naïve human B-lymphocytes infected with Epstein-Barr Virus.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0221454 (2019)
Beam size limit for pencil minibeam radiotherapy determined from side effects in an in-vivo mouse ear model.
2019 Scientific Article in Journal of Cell Science J. Cell Sci. 132:jcs223891 (2019)
Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.
2019 Scientific Article in JCI insight JCI insight 4:e130356 (2019)
In situ metabolomics of aldosterone-producing adenomas.
2019 Scientific Article in Clinical Chemistry Clin. Chem. 65, 1276-1286 (2019)
Prognostic relevance of steroid sulfation in adrenocortical carcinoma revealed by molecular phenotyping using high resolution mass spectrometry imaging.
2019 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 17:89 (2019)
Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma.
2019 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 10:487 (2019)
Heat shock protein 90 as a prognostic marker and therapeutic target for adrenocortical carcinoma.
2019 mBio mBio 10:e01482-19 (2019)
MicroRNAs of Epstein-Barr Virus attenuate T-cell-mediated immune control in vivo (vol 10, e01941-18, 2019).
2019 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 116, 16046-16055 (2019)
Epstein-Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection.
2019 Scientific Article in Nature Communications Nat. Commun. 10:3274 (2019)
Involvement of G-quadruplex regions in mammalian replication origin activity.
2019 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 12:dmm039156 (2019)
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:9925 (2019)
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.
2019 Meeting abstract in Journal of Aerosol Medicine and Pulmonary Drug Delivery J. Aerosol Med. Pulm. Drug Deliv. 32, A12-A12 (2019)
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.
2019 Scientific Article in ACS Nano ACS Nano 13, 8114-8123 (2019)
Iron-sequestering nanocompartments as multiplexed Electron Microscopy gene reporters.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:8492 (2019)
Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S24-S25 (2019)
A 16q24.3 4-gene mRNA signature predicts outcome in radio(chemo)therapy-treated head and neck squamous cell carcinoma.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S25-S25 (2019)
A five-microRNA-signature predicts recurrence and survival in HPV-negative HNSCC.
2019 Scientific Article in Veterinary Medicine Austria Wien. Tierärztl. Mschr. 106, 109-115 (2019)
Autochthonous Taenia crassiceps infection in a ring-tailed lemur (Lemur catta) in the Salzburg Zoo.
2019 Scientific Article in Laboratory Investigation Lab. Invest. 99, 1535-1546 (2019)
Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis.
2019 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 216, 1700-1723 (2019)
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 26, 30-44 (2019)
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.
2019 Scientific Article in Cancers Cancers 11:727 (2019)
Acute skin damage and late radiation-induced fibrosis and inflammation in murine ears after high-dose irradiation.
2019 Scientific Article in Cancers Cancers 11:594 (2019)
Impact of extrinsic and intrinsic hypoxia on catecholamine biosynthesis in absence or presence of Hif2 alpha in pheochromocytoma cells.
2019 Scientific Article in Life Science Alliance Life Sci. All. 2:e201800108 (2019)
BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.
2019 Meeting abstract in Molecular Therapy Mol. Ther. 27, 175-176 (2019)
Cord blood derived CAR-T cells targeting gp350 containing CD28/CD3 zeta or 4-1BB/CD3 zeta signaling domains directly react against cells infected with EBV bypassing the need of HLA-matched memory T cells.
2019 Review in Acta neurochirurgica Acta Neurochir. 161, 1109-1124 (2019)
Intracavitary radioimmunotherapy of high-grade gliomas: Present status and future developments.
2019 Scientific Article in Blood Blood 133, 2597-2609 (2019)
Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
2019 Scientific Article in Nature Communications Nat. Commun. 10:1415 (2019)
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.
2019 Scientific Article in Diabetes Diabetes 68, 1329-1340 (2019)
Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway.
2019 Scientific Article in Nature Communications Nat. Commun. 10:1114 (2019)
Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging.
2019 Review in Frontiers in Oncology Front. Oncol. 9:104 (2019)
Progress in EBV vaccines.
2019 Review in Histochemistry and Cell Biology Histochem. Cell Biol. 151, 201-216 (2019)
Novel methods in adrenal research: A metabolomics approach.
2019 Scientific Article in Journal of extracellular vesicles J. Extra. Vesicles 8:1573051 (2019)
Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL.
2019 Scientific Article in PLoS Biology PLoS Biol. 17:e2006767 (2019)
The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0210998 (2019)
Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis.
2019 Scientific Article in Cell Metabolism Cell Metab. 29, 932-949.e4 (2019)
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits.
2019 Scientific Article in Cellular & Molecular Immunology Cell. Mol. Immunol. 16, 412-414 (2019)
Reproducing indolent B-cell lymphoma transformation with T-cell immunosuppression in LMP1/CD40-expressing mice.
2019 Scientific Article in mBio mBio 10:01941-18 (2019)
MicroRNAs of Epstein-Barr Virus attenuate T-cell-mediated immune control in vivo.
2019 Scientific Article in American Journal of Pathology, The Am. J. Pathol. 189, 521-539 (2019)
Spatiotemporally skewed activation of PD-1 T cells after epstein barr virus infection and tumor development in long-term fully humanized mice.
2019 Scientific Article in Proteomics - Clinical Applications Proteomics Clin. Appl. 13:e1800137 (2019)
Integrative clustering in mass spectrometry imaging for enhanced patient stratification.
2019 Scientific Article in ACS Nano ACS Nano 13, 1029-1041 (2019)
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.
2019 Scientific Article in European Journal of Immunology Eur. J. Immunol. 49, 351-352 (2019)
B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?
2019 Scientific Article in Gastroenterology Gastroenterology 156, 203-217.e20 (2019)
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.
2019 Scientific Article in International Journal of Obesity Int. J. Obes. 43, 1305-1318 (2019)
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.
2019 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 25, 1505-1516 (2019)