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Prof. Dr. Daniel Krappmann

Director of Research Unit Cellular Signal Integration

“My research is dedicated to decipher molecular machineries controlling immune activation and to translate this findings into the development of new therapies to fight immune diseases and cancer.”

“My research is dedicated to decipher molecular machineries controlling immune activation and to translate this findings into the development of new therapies to fight immune diseases and cancer.”

Academic Pathway and Research Area

He started his academic career as a PhD student and continued his studies on signal transduction in cancer cells as a postdoctoral fellow and junior group leader at the Max-Delbrück-Center (MDC) for Molecular Medicine in Berlin. His Research Unit at Helmholtz Munich is dedicated to study physiological and pathological signaling pathways in the immune system and in cancer.

The identification of the pro-proliferative and anti-apoptotic function of signaling networks in human tumor cells inspired his long-standing efforts to bridge the gap between basic science and clinical translation. He has been leading a successful drug discovery program and the pre-clinical development of new immune modulatory drugs. Candidate drugs from this program are currently tested in the clinic for their ability to boost our immune defence to fight cancer.

Skills and Expertise

Immunology OncologyCancer 

Cell Signaling   T cell Biology Target Identification Drug Discovery

Professional Career

since 2013

Head of Research Unit ‘Cellular Signal Integration’

since 2012

Adjunct Professor Faculty of Biology, Ludwig-Maximilians-Universität München

2005 - 2012

Group Leader Helmholtz Munich

2002 - 2005

Head Junior Research Group at MDC Berlin

1997 - 2002

Postdoctoral Fellow at Max-Delbrück-Center (MDC) Berlin

Honors and Awards

  • Delbrück Fellowship Award (MDC Berlin)
    2002

Publication Highlights

Complete list of publication