Publications
Széles, E. ; Kondak, D. ; Da Silva, R.C. ; Szabados, L. ; Lindermayr, C. ; Kolbert, Z.
Genetic and bIOCHEMICAL approaches used FOR identification and MECHANISTIC characterization of NitriC oxide-RESPONSIVE plant genes.Yan, W. ; Liu, X. ; Jiang, S. ; Li, H. ; Chi, W. ; Luo, R. ; Peng, J. ; Jiang, F. ; Stöger, T. ; Wajid, A. ; Dodovski, A. ; Gao, C. ; Mingala, C.N. ; Andreychuk, D.B. ; Yin, R.
Emergence and characterization of historically extinct virulent genotype IV Newcastle disease virus in wild and domestic birds: genetic insights, pathogenicity, and vaccine efficacy.Liu, Q. ; Yang, L. ; Li, C. ; Han, L. ; Wilmot, J. ; Yang, G. ; Leinardi, R. ; Zhou, Q. ; Schröppel, A. ; Kutschke, D. ; Secklehner, J. ; Yildirim, A.Ö. ; Huaux, F. ; Zeuschner, D. ; Carlin, L.M. ; Sperandio, M. ; Schmid, O. ; Stöger, T. ; Rehberg, M.
Alveolar macrophages initiate the spatially targeted recruitment of neutrophils after nanoparticle inhalation.Firsova, A.B. ; Marco Salas, S. ; Kuemmerle, L. ; Abalo, X.M. ; Sountoulidis, A. ; Larsson, L. ; Mahbubani, K.T. ; Theelke, J. ; Andrusivova, Z. ; Alonso Galicia, L. ; Liontos, A. ; Balassa, T. ; Kovács, F. ; Horvath, P. ; Chen, Y. ; Gote-Schniering, J. ; Stoleriu, M.-G. ; Behr, J. ; Meyer, K.B. ; Timens, W. ; Schiller, H.B. ; Luecken, M. ; Theis, F.J. ; Lundeberg, J. ; Nilsson, M. ; Nawijn, M.C. ; Samakovlis, C.
Spatial single-cell atlas reveals regional variations in healthy and diseased human lung.Mümmler, C. ; Lenoir, A. ; Götschke, J. ; Gerckens, M. ; Kaiser, M. ; Kayser, M. ; Drick, N. ; Suhling, H. ; Biener, L. ; Pizarro, C. ; Skowasch, D. ; Kneidinger, N. ; Behr, J. ; Milger, K.
Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study.Kumari, N. ; Wright, S.C. ; Witham, C.M. ; Monserrat, L. ; Palafox, M. ; Charles Richard, J.L. ; Costa, C. ; Elkabets, M. ; Agostino, M. ; Klemm, T. ; Eccles, M.K. ; Garnham, A. ; Wu, T. ; Nilsson, J.A. ; Walz, N. ; Venugopal, V. ; Cerra, A. ; Vasilevski, N. ; Bridgeman, S.C. ; Bassi, S. ; Saei, A. ; Helal, M. ; Neundorf, P. ; Riedel, A. ; Rosenfeldt, M. ; Gill, J. ; Pahor, N. ; Hartmann, O. ; Chung, J. ; Sidhu, S.S. ; Moderau, N. ; Jha, S. ; Rodon, J. ; Diefenbacher, M. ; Komander, D. ; Serra, V. ; Eichhorn, P.
USP10/GSK3B-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer.Voss, C. ; Han, L. ; Ansari, M. ; Strunz, M. ; Haefner, V. ; Angelidis, I. ; Mayr, C.H. ; Berthing, T. ; Zhou, Q. ; Günther, E. ; Huzain, O. ; Schmid, O. ; Vogel, U. ; Schniering, J. ; Gaedcke, S. ; Theis, F.J. ; Schiller, H.B. ; Stöger, T.
Toward a ToxAtlas of carbon-based nanomaterials: Single-cell RNA sequencing reveals initiating cell circuits in pulmonary inflammation.Rademacker, S. ; Müller, J.T. ; Kromer, A.P.E. ; Carneiro, S.P. ; Merkel, O.M.
Nanoparticle-mediated siRNA delivery in human epithelial lung cells cultured at the air-liquid interface.Singh, K. ; Shukla, S. ; Kumari, A.P. ; Qurashi, A. ; Verma, A.K. ; Kumar, A.
Repurposing Nitazoxanide to target the expanded r(CGG)n repeat RNA for therapeutic intervention in fragile-X tremor/Ataxia syndrome.Förster, K. ; Strobl, K. ; Kindt, A. ; Häfner, F. ; Schubert, B. ; Heinen, F. ; Flemmer, A.W. ; Steffinger, D. ; Dietrich, O. ; Stoecklein, S. ; Brinkmann, F. ; Hilgendorff, A.
Lung MRI scoring reveals persistence of emphysema-like changes in lungs of infants born preterm at (pre)school age.Korkmaz, R.Ü. ; Omony, J. ; Tan, X. ; Klotz, M. ; Dragunas, G. ; Chen, S. ; Shankhwar, S. ; Ertüz, Z. ; Müller, C. ; Ragab, M. ; Jeridi, A. ; Augustin, R. ; Nawroth, J. ; Kapellos, T. ; Rankl, B. ; Yildirim, A.Ö. ; von Mutius, E.
The therapeutic potential of farm dust extracts in a mouse model of eosinophilic inflammation.Sahu, T. ; Pande, B. ; Kumar, P. ; Khelkar, T. ; Bhaskar, L.V.K.S. ; Verma, H.K.
A perspective on gastrointestinal complications in COVID-19: Clinical features, diagnosis, research, mechanisms, and multidisciplinary management.Biechele, G. ; Fink, N.R. ; Dinkel, J. ; Mehnert, R. ; Starrach, T. ; Schelling, M. ; Hübener, C. ; Mahner, S. ; Wintersperger, B. ; Ricke, J. ; Stöcklein, S.
Fetal cardiac magnetic resonance imaging in left-sided diaphragmatic hernia.Stone, V. ; Moschini, E. ; Murphy, F. ; Hunt, N. ; Blosi, M. ; Hristozov, D. ; Johnston, H. ; Stenton, F. ; Mikolajczyk, A. ; Oomen, A.G. ; Schmid, O. ; Tsiliki, G. ; Brunelli, A. ; Badetti, E. ; Vogel, U. ; Gajewicz-Skretna, A. ; Wohlleben, W.
Minimising data needs to support the safer design of multicomponent nanomaterials – Application of grouping.Dekkers, S. ; Adam, V. ; Battista, V.D. ; Haase, A. ; Prinz, J. ; Nagel, G. ; Fransman, W. ; Persson, M. ; Suarez-Merino, B. ; Wohlleben, W. ; Schmid, O. ; Someren, E.v.
Safe‐and‐sustainable‐by‐design approach and decision support system for advanced materials.Zimmermann, J. ; Schön, J. ; Pfeiffer, V. ; Beutel, T. ; Felker, A. ; Stacher‐Priehse, E. ; Damirov, F. ; Reinmuth, N. ; Hatz, R. ; Schneider, C.P. ; Stoleriu, M.-G.
COPD severity as an independent predictor of long-term survival in operable lung cancer: A retrospective analysis from a high-volume thoracic surgery center.Adam, V. ; Di Battista, V. ; Testard, F. ; Persson, M. ; Persson, D. ; Gargouri, D. ; Filoramo, A. ; Grafström, R.C. ; Kohonen, P. ; Hongisto, V. ; Conolly, M. ; Navas, J.M. ; Skjolding, L.M. ; Gajewicz-Skretna, A. ; Danielsen, P.H. ; Vogel, U. ; Jensen, K.A. ; van Someren, E. ; Dekkers, S. ; Schmid, O. ; Wohlleben, W. ; Suarez Merino, B.
Decision support system for safe-and-sustainable-by-design advanced materials: Case study demonstration.Lunding, L.P. ; Weckmann, M. ; Zissler, U.M. ; Jakwerth, C.A. ; Bodenstein-Sgró, R. ; Webering, S. ; Vock, C. ; Ehlers, J.C. ; Fernandez Ceballos, R.A.M. ; Nemani, S.S.P. ; Reddy, K.D. ; Oliver, B.G.G. ; Vermeulen, C.J. ; van de Berge, M. ; Ober, C. ; Künstner, A. ; Busch, H. ; König, I. ; Garbers, C. ; Schmidt-Weber, C.B. ; Nold, M.F. ; Yildirim, A.Ö. ; Nold-Petry, C.A. ; Orinska, Z. ; Bahmer, T. ; Heyckendorf, J. ; Hansen, G. ; von Mutius, E. ; Rabe, K.F. ; Dittrich, A.M. ; Schaub, B. ; Brinkmann, F. ; Kopp, M.V. ; Wegmann, M.
Immune training of the interleukin 6 gene in airway epithelial cells is central to asthma exacerbations.Kecorius, S. ; Madueno, L. ; Birmili, W. ; Löndahl, J. ; Plauškaite, K. ; Byčenkiene, S. ; Lovrić, M. ; Petric, V. ; Carranza-García, M. ; Jiménez-Navarro, M.J. ; Martínez-Ballesteros, M. ; Weiss, M. ; Schmid, O. ; Cyrys, J. ; Peters, A. ; Kecorius, G.
Urban pollution impact assessment in six lithuanian cities with a focus on road traffic emissions - integrated framework for environmental health studies.Chakraborty, A. ; Giraldo-Arias, J. ; Merl-Pham, J. ; Dick, E. ; Mastalerz, M. ; Zöller, M. ; Marchi, H. ; Le Gleut, R. ; Hatz, R. ; Behr, J. ; Hilgendorff, A. ; Hauck, S.M. ; Staab-Weijnitz, C.A.
Cholesterol regulates airway epithelial cell differentiation by inhibiting p53 nuclear translocation.Wohlleben, W. ; Adam, V. ; Lledo, P.C. ; Dekkers, S. ; Durand, C. ; Haase, A. ; Soeteman-Hernandez, L.G. ; Livieri, A. ; Martel-Martin, S. ; Pizzol, L. ; Rollon, B.P. ; Prenner, S. ; Rein, C. ; Van Someren, E.J.W. ; Fransman, W. ; Zabeo, A. ; Rumbo, C. ; Schmid, O. ; Hristozov, D.
A suite of tools for safe-and-sustainable-by-design advanced materials from the EU projects DIAGONAL, HARMLESS and SUNSHINE.Merl-Pham, J. ; Knüppel, L. ; Binzenhöfer, L. ; Hennen, E. ; Kaminski, N. ; Hatz, R. ; Behr, J. ; Hauck, S.M. ; Hilgendorff, A. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
Collagen post-translational modifications are altered in IPF including within ECM receptor binding motifs.Suanes-Cobos, L. ; Aguilera-Ventura, I. ; Torres-Ramos, M. ; Serrano-Yubero, A. ; Moreno Fernández-Aliseda, C. ; Fernández, S. ; Garrido-Rodríguez, M. ; de la Luna, S. ; Prieto-Garcia, C. ; Diefenbacher, M. ; Mejias-Perez, E. ; Calzado, M.A.
A novel feedback loop between DYRK2 and USP28 regulates cancer homeostasis and DNA damage signaling.Yang, L. ; Han, L. ; Schmid, O. ; Chen, C.
Precision dosimetry in pulmonary drug delivery.Vonficht, D. ; Jopp-Saile, L. ; Yousefian, S. ; Flore, V. ; Simó Vesperinas, I. ; Teuber, R. ; Avanesyan, B. ; Luo, Y. ; Röthemeier, C. ; Grünschläger, F. ; Fernández-Vaquero, M. ; Fregona, V. ; Ordoñez-Rueda, D. ; Schmalbrock, L.K. ; Deininger, L. ; Yamachui Sitcheu, A.J. ; Gu, Z. ; Funk, M.C. ; Mikut, R. ; Heikenwälder, M. ; Eggert, A. ; von Stackelberg, A. ; Kobold, S. ; Krönke, J. ; Keller, U. ; Trumpp, A. ; Hegazy, A.N. ; Eckert, C. ; Hübschmann, D. ; Haas, S.
Ultra-high-scale cytometry-based cellular interaction mapping.Wagner, D.E. ; Alsafadi, H.N. ; Mitash, N. ; Justet, A. ; Hu, Q. ; Pineda, R. ; Staab-Weijnitz, C.A. ; Korfei, M. ; Gvazava, N. ; Wannemo, K. ; Onwuka, U. ; Mozurak, M. ; Estrada-Bernal, A. ; Cala-Garcia, J. ; Mutze, K. ; Costa, R. ; Bölükbas, D.A. ; Stegmayr, J. ; Skronska-Wasek, W. ; Klee, S. ; Ota, C. ; Baarsma, H.A. ; Wang, J. ; Sembrat, J. ; Hilgendorff, A. ; Ding, J. ; Günther, A. ; Chambers, R. ; Rosas, I. ; de Langhe, S. ; Kaminski, N. ; Lehmann, M. ; Eickelberg, O. ; Königshoff, M.
Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models.Mümmler, C. ; Milger, K.
"Clinical and biological remission with tezepelumab: The real-world response in severe uncontrolled asthma".Hagl, B. ; Spielberger, B.D. ; Neumann, B. ; Pelham, S.J. ; Pandey, D. ; Schlundt, A. ; Barro, C. ; Lechner, A. ; Wolf, C. ; Deenick, E.K. ; Sattler, M. ; Tangye, S.G. ; Rothenfusser, S. ; Renner, E.D.
Signal transducer and activator of transcription 3 (STAT3) variant p.K709N causes hyper-IgE syndrome likely by impaired STAT3-dimer formation.Luecken, M. ; Gigante, S. ; Burkhardt, D.B. ; Cannoodt, R. ; Strobl, D.C. ; Markov, N.S. ; Zappia, L. ; Palla, G. ; Lewis, W. ; Dimitrov, D. ; Vinyard, M.E. ; Magruder, D.S. ; Müller, M. ; Andersson, A. ; Dann, E. ; Qin, Q. ; Otto, D.J. ; Klein, M. ; Botvinnik, O.B. ; Deconinck, L. ; Waldrant, K. ; Yasa, S.N. ; Szałata, A. ; Benz, A. ; Li, Z. ; Bloom, J.M. ; Pisco, A.O. ; Saez-Rodriguez, J. ; Wulsin, D. ; Pinello, L. ; Saeys, Y. ; Theis, F.J. ; Krishnaswamy, S.
Defining and benchmarking open problems in single-cell analysis.Jia, J. ; Stathopoulos, G.T.
Pyrimidine addiction: An Achilles' heel of NF2-altered mesothelioma.Naik, T. ; Verma, H.K. ; Mulkalwar, M. ; Mishra, D. ; Bhaskar, L.
Comprehensive meta-analysis on the impact of the MDM2 SNP 309 T>G gene variant in leukemia susceptibility.Miller, Z. ; Twardowski, L.M. ; Reader, B.F. ; Rojas, M. ; Lehmann, M. ; Mora, A.L.
Mechanisms and markers of lung ageing in health and disease.Barnikel, M. ; Milger, K. ; Mertsch, P. ; Arnold, P. ; Leuschner, G. ; Veit, T. ; Gerckens, M. ; Mümmler, C. ; Barton, J. ; Ghiani, A. ; Yildirim, A.Ö. ; Dinkel, J. ; Neurohr, C. ; Behr, J. ; Kneidinger, N.
Classification and course of pulmonary hypertension associated with end-stage COPD.Saarimäki, L.A. ; Fratello, M. ; Del Giudice, G. ; Di Lieto, E. ; Afantitis, A. ; Alenius, H. ; Chiavazzo, E. ; Gulumian, M. ; Karisola, P. ; Lynch, I. ; Mancardi, G.L. ; Melagraki, G. ; Netti, P. ; Papadiamantis, A.G. ; Peijnenburg, W. ; A Santos, H. ; Serchi, T. ; Shahbazi, M.A. ; Stöger, T. ; Valsami-Jones, E. ; Vivo, P. ; Vinković Vrček, I. ; Vogel, U. ; Wick, P. ; Winkler, D.A. ; Serra, A. ; Greco, D.
Wisdom of crowds for supporting the safety evaluation of nanomaterials.Sahu, T. ; Jagzape, A.T. ; Sinha, M. ; Sinha, R. ; Verma, H.K.
New frontiers in sickle cell disease: The role of antiviral therapies and emerging drugs in managing viral infections.Rusznyak, L. ; Wasnick, R. ; Funk, M.C.
Lungen-Organoide bringen neuen Schwung in die COPD-Forschung.Kondak, D. ; Deák, A. ; Rónavári, A. ; Bodor, T. ; Kondak, S. ; Adedokun, O.P. ; Benkő, P. ; Szőllősi, R. ; Szalai, G. ; Janda, T. ; Ayaydin, F. ; Lindermayr, C. ; Kónya, Z. ; Kolbert, Z.
Chitosan encapsulated S-nitrosoglutathione is an efficient nanodonor in Brassica napus seedlings.Sieber-Schaefer, F. ; Jiang, M. ; Kromer, A.P.E. ; Nguyen, A. ; Molbay, M. ; Pinto Carneiro, S. ; Juergens, D. ; Burgstaller, G. ; Popper, B. ; Winkeljann, B. ; Merkel, O.M.
Machine learning-enabled polymer discovery for enhanced pulmonary siRNA delivery.Deng, B. ; Trassl, L. ; Jia, J. ; Skiadas, G. ; Ntaliarda, G. ; Behrend, S.J. ; Schamberger, A.C. ; Yildirim, A.Ö. ; Stathopoulos, G.T. ; Asarian, L. ; Chateau, M.d. ; Fernandez, I.E.
Targeting KRAS-mutant Lung Adenocarcinoma Tumors Through IL-1ß Inhibition.Weckler, B. ; Martin, R.J. ; Kutzinski, M. ; Bertrams, W. ; Jung, A.L. ; Pott, H. ; Laakmann, K. ; Schulte, L.N. ; Ahnert, P. ; Heider, D. ; Ringshandl, S. ; Seidemann, C. ; Suttorp, N. ; Witzenrath, M. ; Wildberg, J. ; Lehmann, M. ; Rohde, G. ; Greulich, T. ; Vogelmeier, C. ; Schmeck, B.
Eosinophil count as biomarker for risk stratification of community-acquired pneumonia: a prospective cohort study.Burgy, O. ; Lehmann, M.
Small packages but big insights: Extracellular vesicles as biomarkers in interstitial lung disease associated with systemic sclerosis.Sui, J. ; Johnson, A.R. ; Kapellos, T. ; Shiva, S. ; Kliment, C.R.
ANT1 deficiency impairs macrophage metabolism and migration, protecting against emphysema in COPD.Prüfer, F. ; Steer, B. ; Kaufmann, E. ; Wolf, P. ; Adler, B. ; Korfei, M. ; Günther, A. ; Königshoff, M. ; Adler, H.
Macrophage C1q contributes to pulmonary fibrosis by disturbing the metabolism of alveolar epithelial cells.Lindermayr, C. ; Yildirim, A.Ö.
Redox-signaling in innate immune memory: Similar mechanisms in animals/humans and plants.Prinz, J. ; Nagel, G. ; Dekkers, S. ; van Someren, E.P. ; Adam, V. ; Battista, V.D. ; Suarez-Merino, B. ; Wohlleben, W. ; Persson, M. ; Baun, A. ; Schmid, O. ; Haase, A.
HARMLESS early warning system for advanced materials.Staab-Weijnitz, C. ; Lehmann, M.
Environmental exposure and the ageing lung.Narvaez, M.M. ; Gölitz, F. ; Jain, E. ; Gote-Schniering, J. ; Stoleriu, M.G. ; Bertrams, W. ; Schmeck, B. ; Yildirim, A.Ö. ; Rauen, U. ; Wille, T. ; Lehmann, M.
Cold Storage of Human Precision-cut Lung Slices Preserves Cellular and Transcriptional Identity Enabling Optimized On-demand Translational Lung Research.Cannoodt, R. ; Deconinck, L. ; Couckuyt, A. ; Markov, N.S. ; Zappia, L. ; Luecken, M. ; Interlandi, M. ; Saeys, Y. ; Saelens, W.
funkyheatmap: Visualising data frames with mixed data types.Zhao, A. ; Rojas, J.J. ; Cao, C. ; Zhang, Y. ; Semenova, A. ; Schiller, H. ; Estépar, R.S.J. ; Bhattacharya, D. ; Sauler, M. ; Polverino, F.
Lung Marginal Zone-like B Cells: A Novel Pathogenic Immune Cell Population in Chronic Obstructive Pulmonary Disease.Zöller, M. ; Mayr, C.H. ; Mastalerz, M. ; Dick, E. ; Chakraborty, A. ; Nakayma, M. ; Simon, L. ; Merl-Pham, J. ; Behr, J. ; Hilgendorff, A. ; Schmid, O. ; Hauck, S.M. ; Schiller, H. ; Staab-Weijnitz, C.A.
Transient and Persistent Airway Proteome Changes Induced by Cigarette Smoke.Zöller, M. ; Mastalerz, M. ; Dick, E. ; Hennen, E. ; Chakraborty, A. ; Merl-Pham, J. ; Marchi, H. ; Le Gleut, R. ; Jeridi, A. ; Prasse, A. ; Jäger, B. ; Santofimia‐Castaño, P. ; Stoleriu, M.-G. ; Hilgendorff, A. ; Yildirim, A.Ö. ; Hauck, S.M. ; Staab-Weijnitz, C.A.
Quantitative Proteomics Identifies Nuclear Protein 1 as a Regulator of Cell Death in Differentiated Primary Human Bronchial Epithelial Cells.Stoleriu, M.-G. ; Ansari, M. ; Strunz, M. ; Schamberger, A.C. ; Heydarian, M. ; Gabriel, C. ; Najak, A. ; Disovic, A. ; Schneider, J. ; Gerckens, M. ; Burgstaller, G. ; Ding, Y. ; Doryab, A. ; Voss, C. ; Ketscher, C. ; Sienel, W. ; Kauke, T. ; Fertmann, J. ; Schneider, C. ; Behr, J. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schubert, B. ; Hauck, S.M. ; Hatz, R. ; Schmid, O. ; Stöger, T. ; Schiller, H. ; Hilgendorff, A.
Development of advanced in-vitro human bronchial epithelial models and lung cell atlas in COPD enabled by thoracic surgery translational research.Hilgendorff, A. ; Kindt-Dunjko, A. ; Häfner, F. ; Förster, K. ; Heydarian, M. ; Hauck, S.M. ; Flemmer, A.W. ; von Toerne, C. ; Sophia, S. ; Toshner, M. ; Sucre, J.M.S.
Interleukin 7 Signaling as an Indicator of Pulmonary Vascular Disease in Preterm Infants Identified by Proteomic Screening and MRI Analysis.Faiz, A. ; Idrees, S. ; Johansen, M. ; Kovács, K.J. ; Boedijono, F. ; Chen, H. ; Galvao, I. ; Donovan, C. ; Kim, R. ; Sikkema, L. ; Strobl, D.C. ; Belz, G.T. ; Segal, L.N. ; Chotirmall, S.H. ; Nawijn, M.C. ; Lehmann, M. ; Kapellos, T. ; Gallego‐Ortega, D. ; Hansbro, P.M.
The Mouse Single Cell Lung Disease Atlas.Kurmi, P. ; Nalabothu, P. ; Sahoo, S. ; Verma, H.K. ; Reddy, S.G. ; Bhaskar, L.V.K.S.
Evaluating the impact of Matrilin-1 gene polymorphisms on mandibular prognathism: A meta-analysis.Nitschkowski, D. ; Vierbuchen, T. ; Heine, H. ; Behrends, J. ; Reiling, N. ; Reck, M. ; Rabe, K.F. ; Kugler, C. ; Ammerpohl, O. ; Drömann, D. ; Muley, T. ; Kriegsmann, M. ; Stathopoulos, G.T. ; Arendt, K.A.M. ; Goldmann, T. ; Marwitz, S.
SMAD2 linker phosphorylation impacts overall survival, proliferation, TGFβ1-dependent gene expression and pluripotency-related proteins in NSCLC.Chakraborty, A. ; Zöller, M. ; Sardogan, A. ; Klotz, M. ; Mastalerz, M. ; Marchi, H. ; Meixner, R. ; Hatz, R.A. ; Behr, J. ; Hilgendorff, A. ; Nakayama, M. ; Staab-Weijnitz, C.A.
Development of a polidocanol-based human in vitro model to explore airway epithelial repair.Gade, N. ; Seifert, P. ; Gerckens, M. ; Mümmler, C. ; Kauke, T. ; Dick, A. ; Veit, T. ; Roden, D. ; Hoffmann, S. ; Scherzer, M. ; Höpler, J. ; Binzenhöfer, L. ; Lanz, H. ; Michel, S. ; Schneider, C. ; Irlbeck, M. ; Tomasi, R. ; Hatz, R. ; Hagl, C. ; Massberg, S. ; Milger, K. ; Behr, J. ; Lüsebrink, E. ; Kneidinger, N.
Association of HLA mismatch with adverse cardiovascular events following lung transplantation: A single-center study.Russo, R.C. ; Togbe, D. ; Couillin, I. ; Segueni, N. ; Han, L. ; Quesniaux, V.F.J. ; Stöger, T. ; Ryffel, B.
Ozone-induced lung injury and inflammation: Pathways and therapeutic targets for pulmonary diseases caused by air pollutants.van der Koog, L. ; Woest, M.E. ; Gorter, I.C. ; Verschut, V. ; Elferink, R.A.B. ; Zuidhof, A.B. ; Nugraha, D.F. ; Koloko Ngassie, M.L. ; Bos, S.I.T. ; Dhakad, D. ; Wolters, J.C. ; Horvatovich, P.L. ; Prakash, Y.S. ; Timens, W. ; Yildirim, A.Ö. ; Brandsma, C.A. ; Frijlink, H.W. ; Nagelkerke, A. ; Gosens, R.
Fibroblast-derived osteoglycin promotes epithelial cell repair.Zappia, L. ; Richter, S. ; Ramirez Suastegui, C. ; Kfuri-Rubens, R. ; Vornholz, L. ; Wang, W. ; Dietrich, O. ; Frishberg, A. ; Luecken, M. ; Theis, F.J.
Feature selection methods affect the performance of scRNA-seq data integration and querying.Salas, S.M. ; Kuemmerle, L. ; Mattsson-Langseth, C. ; Tismeyer, S. ; Avenel, C. ; Hu, T. ; Rehmann, H. ; Grillo, M. ; Czarnewski, P. ; Helgadottir, S. ; Tiklova, K. ; Andersson, A. ; Rafati, N. ; Chatzinikolaou, M. ; Theis, F.J. ; Luecken, M. ; Wählby, C. ; Ishaque, N. ; Nilsson, M.
Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows.Suri, C. ; Pande, B. ; Sahithi, L.S. ; Swarnkar, S. ; Khelkar, T. ; Verma, H.K.
Metabolic crossroads: Unravelling immune cell dynamics in gastrointestinal cancer drug resistance.Barnikel, M. ; Kneidinger, N. ; Gerckens, M. ; Mümmler, C. ; Lenoir, A. ; Mertsch, P. ; Veit, T. ; Leuschner, G. ; Waelde, A. ; Neurohr, C. ; Behr, J. ; Milger, K.
Current blood eosinophilia does not predict the presence of pulmonary hypertension in patients with end-stage lung disease.Fischer, A. ; Han, W. ; Hu, S. ; Mück-Häusl, M. ; Wannemacher, J. ; Kadri, S. ; Lin, Y. ; Dai, R. ; Christ, S. ; Su, Y. ; Dasgupta, B. ; Sardogan, A. ; Deisenhofer, C. ; Dutta, S. ; Kadri, A. ; Güney, T.G. ; Correa-Gallegos, D. ; Mayr, C.H. ; Hatz, R. ; Stoleriu, M.G. ; Lindner, M. ; Hilgendorff, A. ; Adler, H. ; Machens, H.G. ; Schiller, H.B. ; Hauck, S.M. ; Rinkevich, Y.
Author Correction: Targeting pleuro-alveolar junctions reverses lung fibrosis in mice.Willem, T. ; Shitov, V.A. ; Luecken, M. ; Kilbertus, N. ; Bauer, S. ; Piraud, M. ; Buyx, A. ; Theis, F.J.
Biases in machine-learning models of human single-cell data.Melo-Narváez, C. ; Gölitz, F. ; Jain, E. ; Gote-Schniering, J. ; Stoleriu, M.-G. ; Bertrams, W. ; Schmeck, B. ; Yildirim, A.Ö. ; Rauen, U. ; Wille, T. ; Lehmann, M.
Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies.Fischer, A. ; Han, W. ; Hu, S. ; Mück-Häusl, M. ; Wannemacher, J. ; Kadri, S. ; Lin, Y. ; Dai, R. ; Christ, S. ; Su, Y. ; Dasgupta, B. ; Sardogan, A. ; Deisenhofer, C. ; Dutta, S. ; Kadri, A. ; Güney, T.G. ; Correa-Gallegos, D. ; Mayr, C.H. ; Hatz, R. ; Stoleriu, M.G. ; Lindner, M. ; Hilgendorff, A. ; Adler, H. ; Machens, H.G. ; Schiller, H.B. ; Hauck, S.M. ; Rinkevich, Y.
Targeting pleuro-alveolar junctions reverses lung fibrosis in mice.Müller, J.T. ; Kromer, A.P.E. ; Ezaddoustdar, A. ; Alexopoulos, I. ; Steinegger, K.M. ; Porras-Gonzalez, D.L. ; Berninghausen, O. ; Beckmann, R. ; Braubach, P. ; Burgstaller, G. ; Wygrecka, M. ; Merkel, O.M.
Nebulization of RNA-loaded micelle-embedded polyplexes as a potential treatment of idiopathic pulmonary fibrosis.Han, L. ; Haefner, V. ; Yildirim, A.Ö. ; Adler, H. ; Stöger, T.
Carbonaceous particle exposure triggered accumulation of Osteopontin/SPP1+ macrophages contributes to emphysema development.Reissland, M. ; Hartmann, O. ; Tauch, S. ; Bugter, J.M. ; Prieto-Garcia, C. ; Schulte, C. ; Loebbert, S. ; Solvie, D. ; Bitman-Lotan, E. ; Narain, A. ; Jacomin, A.C. ; Schuelein-Voelk, C. ; Fuss, C.T. ; Pahor, N. ; Ade, C. ; Buck, V. ; Potente, M. ; Li, V. ; Beliu, G. ; Wiegering, A. ; Grossmann, T. ; Eilers, M. ; Wolf, E. ; Maric, H. ; Rosenfeldt, M. ; Maurice, M.M. ; Dikic, I. ; Gallant, P. ; Orian, A. ; Diefenbacher, M.
Correction: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.Li, H. ; Furusawa, T. ; Cavero, R. ; Xiao, Y. ; Chari, R. ; Wu, X. ; Sun, D. ; Hartmann, O. ; Dhall, A. ; Holewinski, R. ; Andresson, T. ; Karim, B. ; Villamor-Payà, M. ; Gallardo, D. ; Day, C.P. ; Pal, L.R. ; Nair, N.U. ; Ruppin, E. ; Aladjem, M.I. ; Pommier, Y. ; Diefenbacher, M. ; Lim, J.M. ; Levine, R.L. ; Stracker, T.H. ; Weyemi, U.
Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition.Korkmaz-Icöz, S. ; Szabo, G. ; Gieldon, A. ; McDonald, P.P. ; Dashkevich, A. ; Yildirim, A.Ö. ; Korkmaz, B.
Protective effects of neutrophil serine protease inhibition against ischemia-reperfusion injury in lung or heart transplantation.Geary, N. ; Asarian, L. ; Leeners, B.
Best practices for including sex as a variable in appetite research.Johnsen, M.B. ; Lehmann, M.
Physiologische und pathophysiologische Veränderungen der alternden Lunge.Götschke, J. ; Walter, J. ; Leuschner, G. ; Gerckens, M. ; Götschke, M. ; Mertsch, P. ; Mümmler, C. ; Lenoir, A. ; Barnikel, M. ; Dinkel, J. ; Behr, J. ; Kneidinger, N. ; Spiro, J. ; Milger, K.
Mucus plug score predicts clinical and pulmonary function response to biologic therapy in patients with severe asthma.Nannu Shankar, S. ; O’Connor, A. ; Mital, K. ; Zhang, Y. ; Theodore, A. ; Shirkhani, A. ; Amanatidis, S. ; Lewis, G.S. ; Eiguren Fernandez, A. ; Tilly, T.B. ; Schmid, O. ; Sabo-Attwood, T. ; Wu, C.Y.
Cellular responses of lung cells cultured at an air-liquid interface are influenced by spatial nanoparticle deposition patterns in an in vitro aerosol exposure system.Sahu, P. ; Verma, H.K. ; Bhaskar, L.V.K.S.
Alcohol and alcoholism associated neurological disorders: Current updates in a global perspective and recent recommendations.Lehmann, M. ; Krishnan, R. ; Sucre, J. ; Kulkarni, H.S. ; Pineda, R.H. ; Anderson, C. ; Banovich, N.E. ; Behrsing, H.P. ; Dean, C.H. ; Haak, A. ; Gosens, R. ; Kaminski, N. ; Zagorska, A. ; Koziol-White, C. ; Metcalf, J.P. ; Kim, Y.H. ; Loebel, C. ; Neptune, E.R. ; Noël, A. ; Raghu, G. ; Sewald, K. ; Sharma, A. ; Suki, B. ; Sperling, A. ; Tatler, A. ; Turner, S. ; Rosas, I.O. ; Pam Van, R.Y. ; Wille, T. ; Randell, S.H. ; Pryhuber, G. ; Rojas, M. ; Bourke, J. ; Königshoff, M.
Precision-cut lung slices: Emerging tools for preclinical and translational lung research an official american thoracic society workshop report.Chobola, T. ; Liu, Y. ; Zhang, H. ; Schnabel, J.A. ; Peng, T.
Fast context-based low-light image enhancement via neural implicit representations.Kampalli, P.K. ; Ghanta, M.K. ; Verma, H.K. ; Alam, A. ; Peela, S. ; Bhaskar, L.V.K.S.
Exploring the relationship between ERCC1 polymorphisms and colorectal cancer risk: Insights from an in-depth meta-analysis.Sha, Y. ; Yan, W. ; Liu, X. ; Chai, H. ; Chen, J. ; Li, H. ; Wang, M. ; Jiang, S. ; Wang, S. ; Ren, Y. ; Liu, Y. ; Stöger, T. ; Wajid, A. ; Dodovski, A. ; Gao, C. ; Mingala, C.N. ; Andreychuk, D.B. ; Yin, R.
The first report and biological characterization of Avian Orthoavulavirus 16 in wild migratory waterfowl and domestic poultry in China reveal a potential threat to birds.Bukas, C. ; Subramanian, H. ; See, F. ; Steinchen, C. ; Ezhov, I. ; Boosarpu, G. ; Asgharpour, S. ; Burgstaller, G. ; Lehmann, M. ; Kofler, F. ; Piraud, M.
MultiOrg: A Multi-rater organoid-detection dataset.Samakovlis, C. ; Firsova, A.B. ; Salas, S.M. ; Kuemmerle, L. ; Abalo, X.M. ; Larsson, L. ; Mahbubani, K.T. ; Sountoulidis, A. ; Theelke, J. ; Andrusivova, Z. ; Galicia, L.A. ; Liontos, A. ; Balassa, T. ; Kovács, F. ; Horvath, P. ; Chen, Y. ; Schniering, J. ; Stoleriu, M.-G. ; Behr, J. ; Meyer, K. ; Timens, W. ; Schiller, H. ; Luecken, M. ; Theis, F.J. ; Lundeberg, J. ; Nilsson, M. ; Nawijn, M.C.
Topographic atlas of cell states identifies regional gene expression in the adult human lung.Staab-Weijnitz, C.A. ; Hilgendorff, A.
Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis.Johnston, B.D. ; Kreyling, W.G. ; Pfeiffer, C. ; Schäffler, M. ; Sarioglu, H. ; Ristig, S. ; Hirn, S. ; Haberl, N. ; Thalhammer, S. ; Hauck, S.M. ; Semmler-Behnke, M. ; Epple, M. ; Hühn, J. ; Pino, P.D. ; Parak, W.J.
Colloidal stability and surface chemistry are key factors for the composition of the protein corona of inorganic gold nanoparticles.Kreyling, W.G. ; Abdelmonem, A.M. ; Ali, Z. ; Alves, F. ; Geiser, M. ; Haberl, N. ; Hartmann, R. ; Hirn, S. ; de Aberasturi, D.J. ; Kantner, K. ; Khadem-Saba, G. ; Montenegro, J.M. ; Rejman, J. ; Rojo, T. ; Ufartes, R. ; Wenk, A. ; Parak, W.J.
In vivo integrity of polymer-coated gold nanoparticles.Ali, Z. ; Abbasi, A.Z. ; Zhang, F. ; Arosio, P. ; Lascialfari, A. ; Casula, M.F. ; Wenk, A. ; Kreyling, W.G. ; Plapper, R. ; Seidel, M. ; Niessner, R. ; Knöll, J. ; Seubert, A. ; Parak, W.J.
Multifunctional nanoparticles for dual imaging.Estaji, M. ; Nabaei, M. ; Yang, L. ; Schmid, O. ; Farnoud, A.
Aerosol dosimetry in the whole conducting zone of a murine left-lung using CF-PD and LSFM images.Wu, C.Y. ; Melo-Narváez, M.C ; Cuevas-Ocaña, S.
Early career member highlights from the 22nd ERS Lung Science Conference: Development of chronic lung diseases - from life-spanning mechanisms to preventive therapy.Hrovatin, K. ; Sikkema, L. ; Shitov, V.A. ; Heimberg, G. ; Shulman, M. ; Oliver, A.J. ; Müller, M. ; Ibarra Del Rio, I.A. ; Wang, H. ; Ramirez Suastegui, C. ; He, P. ; Schaar, A. ; Teichmann, S.A. ; Theis, F.J. ; Luecken, M.
Considerations for building and using integrated single-cell atlases.Steinegger, K.M. ; Allmendinger, L. ; Sturm, S. ; Sieber-Schäfer, F. ; Kromer, A.P.E. ; Muller-Caspary, K. ; Winkeljann, B. ; Merkel, O.M.
Molecular dynamics simulations elucidate the molecular organization of poly(beta-amino ester) based polyplexes for siRNA delivery.Rathnayake, S.N.H. ; Cruz, J. ; Cuevas Ocaña, S. ; Lehmann, M. ; Demeyer, H.
The more stars, the brighter! Interview with the ECM award winner 2023.Papargyriou, A. ; Najajreh, M. ; Cook, D.P. ; Maurer, C.H. ; Bärthel, S. ; Messal, H.A. ; Ravichandran, S.K. ; Richter, T. ; Knolle, M. ; Metzler, T. ; Shastri, A.R. ; Öllinger, R. ; Jasper, J. ; Schmidleitner, L. ; Wang, S. ; Schneeweis, C. ; Ishikawa-Ankerhold, H. ; Engleitner, T. ; Mataite, L. ; Semina, M. ; Trabulssi, H. ; Lange, S. ; Ravichandra, A. ; Schuster, M. ; Mueller, S. ; Peschke, K. ; Schäfer, A. ; Dobiasch, S. ; Combs, S.E. ; Schmid, R.M. ; Bausch, A.R. ; Braren, R. ; Heid, I. ; Scheel, C. ; Schneider, G. ; Zeigerer, A. ; Luecken, M. ; Steiger, K. ; Kaissis, G. ; van Rheenen, J. ; Theis, F.J. ; Saur, D. ; Rad, R. ; Reichert, M.
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.Funk, M.C. ; Nawroth, J. ; Lehmann, M.
A breath of the future: A novel human model for COPD and beyond.Rong, Z. ; Mai, H. ; Ebert, G. ; Kapoor, S. ; Puelles, V.G. ; Czogalla, J. ; Hu, S. ; Su, J. ; Prtvar, D. ; Singh, I. ; Schädler, J. ; Delbridge, C. ; Steinke, H. ; Frenzel, H. ; Schmidt, K. ; Braun, C. ; Bruch, G. ; Ruf, V. ; Ali, M. ; Sühs, K.W. ; Nemati, M. ; Hopfner, F. ; Ulukaya, S. ; Jeridi, D. ; Mistretta, D. ; Caliskan, Ö.S. ; Wettengel, J.M. ; Cherif, F. ; Kolabas, Z.I. ; Molbay, M. ; Horvath, I. ; Zhao, S. ; Krahmer, N. ; Yildirim, A.Ö. ; Ussar, S. ; Herms, J. ; Huber, T.B. ; Tahirovic, S. ; Schwarzmaier, S.M. ; Plesnila, N. ; Höglinger, G. ; Ondruschka, B. ; Bechmann, I. ; Protzer, U. ; Elsner, M. ; Bhatia, H.S. ; Hellal, F. ; Ertürk, A.
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19.Yang, L. ; Liu, Q. ; Kumar, P. ; Sengupta, A. ; Farnoud, A. ; Shen, R. ; Trofimova, D. ; Ziegler, S. ; Davoudi, N. ; Doryab, A. ; Yildirim, A.Ö. ; Diefenbacher, M. ; Schiller, H. ; Razansky, D. ; Piraud, M. ; Burgstaller, G. ; Kreyling, W.G. ; Isensee, F. ; Rehberg, M. ; Stöger, T. ; Schmid, O.
LungVis 1.0: An automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages.Wang, Y. ; Chen, P. ; Wen, H. ; Gui, X. ; Yan, D. ; Huang, D. ; Wang, D.
Advanced nanoplatform mediated by CRISPR-Cas9 and aggregation-induced emission photosensitizers to boost cancer theranostics.Kuemmerle, L. ; Luecken, M. ; Firsova, A.B. ; Barros De Andrade E Sousa, L. ; Straßer, L. ; Mekki, I.I ; Campi, F. ; Heumos, L. ; Shulman, M. ; Beliaeva, V. ; Hediyeh-Zadeh, S. ; Schaar, A. ; Mahbubani, K.T. ; Sountoulidis, A. ; Balassa, T. ; Kovács, F. ; Horvath, P. ; Piraud, M. ; Ertürk, A. ; Samakovlis, C. ; Theis, F.J.
Probe set selection for targeted spatial transcriptomics.Heumos, S. ; Heuer, M.L. ; Hanssen, F. ; Heumos, L. ; Guarracino, A. ; Heringer, P. ; Ehmele, P. ; Prins, P. ; Garrison, E. ; Nahnsen, S.
Cluster-efficient pangenome graph construction with nf-core/pangenome.Wang, Y. ; Rambold, U. ; Fiedler, P. ; Babushku, T. ; Tapken, C.L. ; Hoefig, K.P. ; Hofer, T.P. ; Adler, H. ; Yildirim, A.Ö. ; Strobl, L.J. ; Zimber-Strobl, U.
CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells.Reissland, M. ; Hartmann, O. ; Tauch, S. ; Bugter, J.M. ; Prieto-Garcia, C. ; Schulte, C. ; Loebbert, S. ; Solvie, D. ; Bitman-Lotan, E. ; Narain, A. ; Jacomin, A.C. ; Schuelein-Voelk, C. ; Fuss, C.T. ; Pahor, N. ; Ade, C. ; Buck, V. ; Potente, M. ; Li, V. ; Beliu, G. ; Wiegering, A. ; Grossmann, T. ; Eilers, M. ; Wolf, E. ; Maric, H. ; Rosenfeldt, M. ; Maurice, M.M. ; Dikic, I. ; Gallant, P. ; Orian, A. ; Diefenbacher, M.
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.Sui, J. ; Xiao, H. ; Mbaekwe, U. ; Ting, N.C. ; Murday, K. ; Hu, Q. ; Gregory, A.D. ; Kapellos, T. ; Yildirim, A.Ö. ; Königshoff, M. ; Zhang, Y. ; Sciurba, F.C. ; Das, J. ; Kliment, C.R.
Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD.Wang, S. ; Liu, X. ; Chen, J. ; Yan, W. ; Li, H. ; Chi, W. ; Luo, R. ; Lin, X. ; Yin, Y. ; Dong, C. ; Wang, H. ; Zheng, B. ; Liu, Y. ; Stöger, T. ; Wajid, A. ; Dodovski, A. ; Gao, C. ; Mingala, C.N. ; Andreychuk, D.B. ; Yin, R.
First detection and biological characterization of an avian metaavulavirus 8 isolated from a migratory swan goose in Qinghai Lake, Northwest China.Burgy, O. ; Mayr, C.H. ; Schenesse, D. ; Fousekis Papakonstantinou, E. ; Ballester, B. ; Sengupta, A. ; She, Y. ; Hu, Q. ; Melo-Narváez, M.C ; Jain, E. ; Pestoni, J. ; Mozurak, M. ; Estrada-Bernal, A. ; Onwuka, U. ; Coughlan, C. ; Parimon, T. ; Chen, P. ; Heimerl, T. ; Bange, G. ; Schmeck, B.T. ; Lindner, M. ; Hilgendorff, A. ; Ruppert, C. ; Guenther, A. ; Mann, M. ; Yildirim, A.Ö. ; Eickelberg, O. ; Jung, A.L. ; Schiller, H. ; Lehmann, M. ; Burgstaller, G. ; Königshoff, M.
Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis.Suri, C. ; Swarnkar, S. ; Bhaskar, L. ; Verma, H.K.
Non-coding RNA as a biomarker in lung cancer.Suri, C. ; Pande, B. ; Sahithi, L.S. ; Sahu, T. ; Verma, H.K.
Interplay between lung diseases and viral infections: A comprehensive review.Kumar, V. ; Yildirim, A.Ö. ; Nawroth, P.
The role of DNA damage in diabetic complications.Heumos, L. ; Ehmele, P. ; Treis, T. ; Upmeier Zu Belzen, J. ; Roellin, E. ; May, L. ; Namsaraeva, A. ; Horlava, N. ; Shitov, V.A. ; Zhang, X. ; Zappia, L. ; Knöll, R. ; Lang, N.J. ; Hetzel, L. ; Virshup, I. ; Sikkema, L. ; Curion, F. ; Eils, R. ; Schiller, H. ; Hilgendorff, A. ; Theis, F.J.
An open-source framework for end-to-end analysis of electronic health record data.Gerckens, M. ; Mümmler, C. ; Richard, A. ; Strodel, J. ; Mertsch, P. ; Milger, K. ; Veit, T. ; Gade, N. ; Yildirim, A.Ö. ; Schneider, C. ; Kauke, T. ; Michel, S. ; Irlbeck, M. ; Behr, J. ; Kneidinger, N.
Characterization of baseline lung allograft dysfunction in single lung transplant recipients.Yildirim, A.Ö. ; Conlon, T.M. ; Adcock, I.M. ; Gosens, R. ; Lehmann, M. ; Kapellos, T. ; Tesfaigzi, Y. ; Polverino, F. ; Sauler, M. ; Wasnick, R. ; Neptune, E.R.
COPD-iNET: A call to the lung community for action to combat the global epidemic of COPD.Kolbert, Z. ; Barroso, J.B. ; Boscari, A. ; Corpas, F.J. ; Gupta, K.J. ; Hancock, J.T. ; Lindermayr, C. ; Palma, J.M. ; Petřivalský, M. ; Wendehenne, D. ; Loake, G.J.
Interorgan, intraorgan and interplant communication mediated by nitric oxide and related species.Damirov, F. ; Stoleriu, M.-G. ; Manapov, F. ; Boedeker, E. ; Dreher, S. ; Gerz, S. ; Hehr, T. ; Sandner, E. ; Ott, G. ; Hatz, R. ; Preissler, G.
Perioperative predictive factors for tumor regression and survival in non-Small cell lung cancer patients undergoing neoadjuvant treatment and lung resection.Li, C. ; Liu, Q. ; Han, L. ; Zhang, H. ; Immler, R. ; Rathkolb, B. ; Secklehner, J. ; Hrabě de Angelis, M. ; Yildirim, A.Ö. ; Zeuschner, D. ; Nicke, A. ; Carlin, L.M. ; Sperandio, M. ; Stöger, T. ; Rehberg, M.
The eATP/P2×7R axis drives quantum dot-nanoparticle induced neutrophil recruitment in the pulmonary microcirculation.Schneider, C. [extern] ; Michel, S. ; Kneidinger, N. ; Fertmann, J. [extern] ; Kleid, L. [extern] ; Walter, J. [extern] ; Moehnle, P. [extern] ; Wichmann, C. [extern] ; Kovác, J. [extern] ; Humpe, A. [extern] ; Schneider, C. [extern] ; Irlbeck, M. [extern] ; Dick, A. [extern] ; Kauke, T. [extern]
High-risk HLA-DQ mismatches are associated with adverse outcomes after lung transplantation.Biechele, G. ; Koliogiannis, V. ; Rennollet, P. ; Prester, T. ; Schulz, E. ; Kolben, T. ; Jegen, M. ; Hübener, C. ; Hasbargen, U. ; Flemmer, A. ; Dietrich, O. ; Burkard, T. ; Schinner, R. ; Dinkel, J. ; Muenchhoff, M. ; Hintz, S. ; Delius, M. ; Mahner, S. ; Ricke, J. ; Hilgendorff, A. ; Stöcklein, S.
Preserved prenatal lung growth assessed by fetal MRI in the omicron-dominated phase of the SARS-CoV-2 pandemic.Jia, J. ; Trassl, L. ; Kong, F. ; Deng, B. ; Liu, R. ; Sun, Z. ; Lan, X. ; Yildirim, A.Ö. ; Stathopoulos, G.T. ; Fernandez, I.E. ; Schamberger, A.C.
Improved survival of patients with stage III small-cell lung cancer with primary resection: A SEER-based analysis.Hu, Y. ; Hu, Q. ; Ansari, M. ; Riemondy, K. ; Pineda, R.H. ; Sembrat, J. ; Leme, A.S. ; Ngo, K. ; Morgenthaler, O. ; Ha, K. ; Gao, B. ; Janssen, W.J. ; Basil, M.C. ; Kliment, C.R. ; Morrisey, E. ; Lehmann, M. ; Evans, C.M. ; Schiller, H. ; Königshoff, M.
Airway derived emphysema-specific alveolar type II cells exhibit impaired regenerative potential in COPD.Ma-Lauer, Y. ; Li, P. ; Niemeyer, D. ; Richter, A. ; Pusl, K. ; von Brunn, B. ; Ru, Y. ; Xiang, C. ; Schwinghammer, S. ; Liu, J. ; Baral, P. ; Berthold, E. ; Qiu, H. ; Roy, A. ; Kremmer, E. ; Flaswinkel, H. ; Drosten, C. ; Jin, Z. ; von Brunn, A.
Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication.Coppens, A. ; Verleden, S.E. ; Claes, E. ; Voet, H. ; Verleden, G.M. ; Lapperre, T.S. ; Yildirim, A.Ö. ; Jungraithmayr, W. ; Yamada, Y. ; Peeters, D.J. ; Hendriks, J.M.H.
Murine orthotopic lung transplant models: A comprehensive overview of genetic mismatch degrees and histopathological insights into chronic lung allograft dysfunction.Jiang, M. ; Zhang, Y. ; Zheng, T. ; Chang, Y. ; Qiao, N. ; Qin, M. ; He, P. ; He, C. ; Du, G. ; Merkel, O.M. ; Sun, X.
Transdermal microneedles integrating biomimetic self-adjuvant particles for enhanced immunity.Hristozov, D. ; Badetti, E. ; Bigini, P. ; Brunelli, A. ; Dekkers, S. ; Diomede, L. ; Doak, S.H. ; Fransman, W. ; Gajewicz-Skretna, A. ; Giubilato, E. ; Gómez-Cuadrado, L. ; Grafström, R.C. ; Gutleb, A.C. ; Halappanavar, S. ; Hischier, R. ; Hunt, N. ; Katsumiti, A. ; Kermanizadeh, A. ; Marcomini, A. ; Moschini, E. ; Oomen, A.G. ; Pizzol, L. ; Rumbo, C. ; Schmid, O. ; Shandilya, N. ; Stone, V. ; Stoycheva, S. ; Stöger, T. ; Merino, B.S. ; Tran, L. ; Tsiliki, G. ; Vogel, U.B. ; Wohlleben, W. ; Zabeo, A.
Next generation risk assessment approaches for advanced nanomaterials: current status and future perspectives.Melo-Narváez, M.C ; Bramey, N. ; See, F. ; Heinzelmann, K. ; Ballester, B. ; Steinchen, C. ; Jain, E. ; Federl, K. ; Hu, Q. ; Dhakad, D. ; Behr, J. ; Eickelberg, O. ; Yildirim, A.Ö. ; Königshoff, M. ; Lehmann, M.
Stimuli-specific senescence of primary human lung fibroblasts modulates alveolar stem cell function.Raina, N. ; Singh, M. ; Rani, R. ; Garg, A.D. ; Sharma, A. ; Kumar, P. ; Gupta, M.
Polymeric micelles for drug delivery: Properties, designs and applications.Furusawa, T. ; Cavero, R. ; Liu, Y. ; Li, H. ; Xu, X. ; Andresson, T. ; Reinhold, W.C. ; White, O. ; Boufraqech, M. ; Meyer, T.J. ; Hartmann, O. ; Diefenbacher, M. ; Pommier, Y. ; Weyemi, U.
Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer.Vogt, M.A. ; Dudvarski Stankovic, N. ; Cruz Garcia, Y. ; Hofstetter, J. ; Schneider, K. ; Kuybu, F. ; Hauck, T.E. ; Adhikari, B. ; Hamann, A. ; Rocca, Y. ; Grysczyk, L. ; Martin, B. ; Gebhardt-Wolf, A. ; Wiegering, A. ; Diefenbacher, M. ; Gasteiger, G. ; Knapp, S. ; Saur, D. ; Eilers, M. ; Rosenfeldt, M. ; Erhard, F. ; Vos, S.M. ; Wolf, E.
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2.Abbas, R. ; Hartmann, O. ; Asiss, D.T. ; Abbas, R. ; Kagan, J. ; Kim, H.T. ; Oren, M. ; Diefenbacher, M. ; Orian, A. ; Larisch, S.
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP.Sierra-Marquez, J. ; Schaller, L. ; Sassenbach, L. ; Ramírez-Fernández, A. ; Alt, P. ; Rissiek, B. ; Zimmer, B. ; Schredelseker, J. ; Hector, J. ; Stähler, T. ; Koch-Nolte, F. ; Staab-Weijnitz, C.A. ; Dietrich, A. ; Kopp, R. ; Nicke, A.
Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction.Shahzad, T. ; Dong, Y. ; Behnke, N.K. ; Brandner, J. ; Hilgendorff, A. ; Chao, C.M. ; Behnke, J. ; Bellusci, S. ; Ehrhardt, H.
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung.Stoleriu, M.-G. ; Pienn, M. ; Joerres, R.A. ; Alter, P. ; Fero, T. ; Urschler, M. ; Kovács, G. ; Olschewski, H. ; Kauczor, H.U. ; Wielpütz, M.O. ; Jobst, B. ; Welte, T. ; Behr, J. ; Trudzinski, F.C. ; Bals, R. ; Watz, H. ; Vogelmeier, C.F. ; Biederer, J. ; Kahnert, K.
Expiratory venous volume and arterial tortuosity are associated with disease severity and mortality risk in patients with COPD: Results from COSYCONET.Suri, C. ; Pande, B. ; Sahu, T. ; Sahithi, L.S. ; Verma, H.K.
Revolutionizing gastrointestinal disorder management: Cutting-edge advances and future prospects.Carneiro, S.P. ; Müller, J.T. ; Merkel, O.M.
Fluorescent Techniques for RNA Detection in Nanoparticles.Curion, F. ; Rich-Griffin, C. ; Agarwal, D. ; Ouologuem, S. ; Rue-Albrecht, K. ; May, L. ; Garcia, G.E.L. ; Heumos, L. ; Thomas, T. ; Lason, W. ; Sims, D. ; Theis, F.J. ; Dendrou, C.A.
Panpipes: A pipeline for multiomic single-cell and spatial transcriptomic data analysis.Gupta, V.K. ; Sahu, L. ; Sonwal, S. ; Suneetha, A. ; Kim, D.H. ; Kim, J. ; Verma, H.K. ; Pavitra, E. ; Raju, G.S.R. ; Bhaskar, L. ; Lee, H.U. ; Huh, Y.S.
Advances in biomedical applications of vitamin D for VDR targeted management of obesity and cancer.Curion, F. ; Wu, X. ; Heumos, L. ; Gonzales André, M.M. ; Halle, L. ; Ozols, M. ; Grant-Peters, M. ; Rich-Griffin, C. ; Yeung, H.Y. ; Dendrou, C.A. ; Schiller, H. ; Theis, F.J.
hadge: A comprehensive pipeline for donor deconvolution in single-cell studies.Pande, B. ; Verma, H.K. ; Bhaskar, L.
Tailored nutritional interventions: A precision approach to managing gestational diabetes mellitus.Berndt, C. ; Alborzinia, H. ; Amen, V.S. ; Ayton, S. ; Barayeu, U. ; Bartelt, A. ; Bayir, H. ; Bebber, C.M. ; Birsoy, K. ; Böttcher, J.P. ; Brabletz, S. ; Brabletz, T. ; Brown, A.R. ; Brüne, B. ; Bulli, G. ; Bruneau, A. ; Chen, Q. ; DeNicola, G.M. ; Dick, T.P. ; Distéfano, A. ; Dixon, S.J. ; Engler, J.B. ; Esser-von Bieren, J. ; Fedorova, M. ; Friedmann Angeli, J.P. ; Friese, M.A. ; Fuhrmann, D.C. ; García-Sáez, A.J. ; Garbowicz, K. ; Götz, M. ; Gu, W. ; Hammerich, L. ; Hassannia, B. ; Jiang, X. ; Jeridi, A. ; Kang, Y.P. ; Kagan, V.E. ; Konrad, D.B. ; Kotschi, S. ; Lei, P. ; Le Tertre, M. ; Lev, S. ; Liang, D. ; Linkermann, A. ; Lohr, C. ; Lorenz, S. ; Luedde, T. ; Methner, A. ; Michalke, B. ; Milton, A.V. ; Min, J. ; Mishima, E. ; Müller, S. ; Motohashi, H. ; Muckenthaler, M.U. ; Murakami, S. ; Olzmann, J.A. ; Pagnussat, G.C. ; Pan, Z. ; Papagiannakopoulos, T. ; Pedrera Puentes, L. ; Pratt, D.A. ; Proneth, B. ; Ramsauer, L. ; Rodriguez, R. ; Saito, Y. ; Schmidt, F. ; Schmitt, C. ; Schulze, A. ; Schwab, A. ; Schwantes, A. ; Soula, M. ; Spitzlberger, B. ; Stockwell, B.R. ; Thewes, L. ; Thorn-Seshold, O. ; Toyokuni, S. ; Tonnus, W. ; Trumpp, A. ; Vandenabeele, P. ; Vanden Berghe, T. ; Venkataramani, V. ; Vogel, F.C.E. ; von Karstedt, S. ; Wang, F. ; Westermann, F. ; Wientjens, C. ; Wilhelm, C. ; Wölk, M. ; Wu, K. ; Yang, X. ; Yu, F. ; Zou, Y. ; Conrad, M.
Ferroptosis in health and disease.Pavitra, E. ; Acharya, R.K. ; Gupta, V.K. ; Verma, H.K. ; Kang, H. ; Lee, J.H. ; Sahu, T. ; Bhaskar, L. ; Raju, G.S.R. ; Huh, Y.S.
Impacts of oxidative stress and anti-oxidants on the development, pathogenesis, and therapy of sickle cell disease: A comprehensive review.Wohlleben, W. ; Persson, M. ; Suarez-Merino, B. ; Baun, A. ; Di Battista, V. ; Dekkers, S. ; van Someren, E.P. ; Broßell, D. ; Stahlmecke, B. ; Wiemann, M. ; Schmid, O. ; Haase, A.
Advanced materials earliest assessment (AMEA).Burt, M. ; Angelidou, G. ; Mais, C.N. ; Preußer, C. ; Glatter, T. ; Heimerl, T. ; Groß, R. ; Serrania, J. ; Boosarpu, G. ; Pogge von Strandmann, E. ; Müller, J.A. ; Bange, G. ; Becker, A. ; Lehmann, M. ; Jonigk, D. ; Neubert, L. ; Freitag, H. ; Paczia, N. ; Schmeck, B. ; Jung, A.L.
Lipid A in outer membrane vesicles shields bacteria from polymyxins.Mohanty, P. ; Pande, B. ; Acharya, R. ; Bhaskar, L.V.K.S. ; Verma, H.K.
Unravelling the triad of lung cancer, drug resistance, and metabolic pathways.Palumbo, F. ; Gunjak, M. ; Lee, P.J. ; Gunther, S. ; Hilgendorff, A. ; Vadász, I. ; Herold, S. ; Seeger, W. ; Mühlfeld, C. ; Morty, R.E.
Impact of different tissue dissociation protocols on endothelial cell recovery from developing mouse lungs.Ciora, O.A. ; Seegmüller, T. ; Fischer, J.S. ; Wirth, T. ; Häfner, F. ; Stöcklein, S. ; Flemmer, A.W. ; Förster, K. ; Kindt, A. ; Bassler, D. ; Poets, C.F. ; Ahmidi, N. ; Hilgendorff, A.
Delineating morbidity patterns in preterm infants at near-term age using a data-driven approach.Babushku, T. ; Lechner, M. ; Ehrenberg, S. ; Rambold, U. ; Schmidt-Supprian, M. ; Yates, A.J. ; Rane, S. ; Zimber-Strobl, U. ; Strobl, L.J.
Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization.Patel, A. ; Sahu, N. ; Verma, H.K. ; Bhaskar, L.V.K.S.
Increased susceptibility for nonsyndromic cleft lip with or without cleft palate by SLC19A1 80G>A genetic variation.Kerckhof, P. ; Ambrocio, G.P.L. ; Beeckmans, H. ; Kaes, J. ; Geudens, V. ; Bos, S. ; Willems, L. ; Vermaut, A. ; Vermant, M. ; Goos, T. ; De Fays, C. ; Aversa, L. ; Mohamady, Y. ; Vanstapel, A. ; Orlitová, M. ; Van Slambrouck, J. ; Jin, X. ; Varghese, V. ; Josipovic, I. ; Boone, M.N. ; Dupont, L.J. ; Weynand, B. ; Dubbeldam, A. ; Van Raemdonck, D.E. ; Ceulemans, L.J. ; Gayan-Ramirez, G. ; De Sadeleer, L.J. ; McDonough, J.E. ; Vanaudenaerde, B.M. ; Vos, R.
Ventilatory capacity in CLAD is driven by dysfunctional airway structure.Costanzo, V. ; Ratre, Y.K. ; Andretta, E. ; Acharya, R. ; Bhaskar, L.V.K.S. ; Verma, H.K.
A comprehensive review of cancer drug-induced cardiotoxicity in blood cancer patients: Current perspectives and therapeutic strategies.Pfeuffer, J. ; Bielow, C. ; Wein, S. ; Jeong, K. ; Netz, E. ; Walter, A. ; Alka, O. ; Nilse, L. ; Colaianni, P.D. ; McCloskey, D. ; Kim, J. ; Rosenberger, G. ; Bichmann, L. ; Walzer, M. ; Veit, J. ; Boudaud, B. ; Bernt, M. ; Patikas, N. ; Pilz, M. ; Startek, M.P. ; Kutuzova, S. ; Heumos, L. ; Charkow, J. ; Sing, J.C. ; Feroz, A. ; Siraj, A. ; Weisser, H. ; Dijkstra, T.M.H. ; Perez-Riverol, Y. ; Röst, H.L. ; Kohlbacher, O. ; Sachsenberg, T.
OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data.Kaes, J. ; Pollenus, E. ; Hooft, C. ; Liu, H. ; Aelbrecht, C. ; Cambier, S. ; Jin, X. ; Van Slambrouck, J. ; Beeckmans, H. ; Kerckhof, P. ; Velde, G.V. ; Van Raemdonck, D. ; Yildirim, A.Ö. ; Van den Steen, P.E. ; Vos, R. ; Ceulemans, L.J. ; Vanaudenaerde, B.M.
The immunopathology of pulmonary rejection after murine lung transplantation.Stoleriu, M.-G. ; Ansari, M. ; Strunz, M. ; Schamberger, A.C. ; Heydarian, M. ; Ding, Y. ; Voss, C. ; Schneider, J.J. ; Gerckens, M. ; Burgstaller, G. ; Castelblanco, A. ; Kauke, T. ; Fertmann, J. ; Schneider, C. ; Behr, J. ; Lindner, M. ; Stacher-Priehse, E. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schubert, B. ; Hauck, S.M. ; Schmid, O. ; Hatz, R.A. ; Stöger, T. ; Schiller, H. ; Hilgendorff, A.
COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors.Di Battista, V. ; Sanchez-Lievanos, K.R. ; Jeliazkova, N. ; Murphy, F. ; Tsiliki, G. ; Zabeo, A. ; Gajewicz-Skretna, A. ; Mikołajczyk, A. ; Hristozov, D. ; Stone, V. ; Schmid, O. ; Hunt, N. ; Oomen, A.G. ; Wohlleben, W.
Similarity of multicomponent nanomaterials in a safer-by-design context: The case of core-shell quantum dots.Zhou, Q. ; Liu, Q. ; Wang, Y. ; Chen, J. ; Schmid, O. ; Rehberg, M. ; Yang, L.
Bridging smart nanosystems with clinically relevant models and advanced imaging for precision drug delivery.Correa-Gallegos, D. ; Ye, H. ; Dasgupta, B. ; Sardogan, A. ; Kadri, S. ; Kandi, R. ; Dai, R. ; Lin, Y. ; Kopplin, R. ; Shantaram Shenai, D. ; Wannemacher, J. ; Ichijo, R. ; Jiang, D. ; Strunz, M. ; Ansari, M. ; Angelidis, I. ; Schiller, H. B. ; Volz, T. ; Machens, H.G. ; Rinkevich, Y.
Author Correction: CD201+ fascia progenitors choreograph injury repair.Mayr, C. ; Sengupta, A. ; Asgharpour, S. ; Ansari, M. ; Pestoni, J. ; Ogar, P. ; Angelidis, I. ; Liontos, A. ; Rodriguez-Castillo, J.A. ; Lang, N.J. ; Strunz, M. ; Porras-Gonzalez, D.L. ; Gerckens, M. ; De Sadeleer, L.J. ; Oehrle, B. ; Viteri-Alvarez, V. ; Fernandez, I.E. ; Tallquist, M. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Stoleriu, M.G. ; Behr, J. ; Kneidinger, N. ; Wuyts, W.A. ; Wasnick, R. ; Yildirim, A.Ö. ; Ahlbrecht, K. ; Morty, R.E. ; Samakovlis, C. ; Theis, F.J. ; Burgstaller, G. ; Schiller, H.
Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts.Carneiro, S. ; Müller, J.T. ; Merkel, O.M.
Targeted molecular therapeutics for pulmonary diseases: Addressing the need for precise drug delivery.Song, S. ; van Dijk, F. ; Vasse, G.F. ; Liu, Q. ; Gosselink, I.F. ; Weltjens, E. ; Remels, A.H. ; de Jager, M.H. ; Bos, S. ; Li, C. ; Stöger, T. ; Rehberg, M. ; Kutschke, D. ; van Eck, G. ; Wu, X. ; Willems, S.H. ; Boom, D. ; Kooter, I.M. ; Spierings, D. ; Wardenaar, R. ; Cole, M. ; Nawijn, M.C. ; Salvati, A. ; Gosens, R. ; Melgert, B.N.
Inhalable textile microplastic fibers impair airway epithelial differentiation.Shilpi, S. ; Gulbake, A.S. ; Chouhan, S. ; Kumar, P.
Functionalized carbon nanotubes, graphene oxide, fullerenes, and nanodiamonds: Emerging theranostic nanomedicines.Rosenkranz, S. ; Pausch, C. ; Coghlan, J.G. ; Huscher, D. ; Pittrow, D. ; Grünig, E. ; Staehler, G. ; Vizza, C.D. ; Gall, H. ; Distler, O. ; Delcroix, M. ; Ghofrani, H.A. ; Ewert, R. ; Kabitz, H.J. ; Skowasch, D. ; Behr, J. ; Milger, K. ; Halank, M. ; Wilkens, H. ; Seyfarth, H.J. ; Held, M. ; Scelsi, L. ; Neurohr, C. ; Vonk-Noordegraaf, A. ; Ulrich, S. ; Klose, H. ; Claussen, M. ; Eisenmann, S. ; Schmidt, K.H. ; Remppis, B.A. ; Skride, A. ; Jureviciene, E. ; Gumbiene, L. ; Miliauskas, S. ; Löffler-Ragg, J. ; Lange, T.J. ; Olsson, K.M. ; Hoeper, M.M. ; Opitz, C.
Risk stratification and response to therapy in patients with pulmonary arterial hypertension and comorbidities: A COMPERA analysis.Castelblanco, A. ; Matzeu, G. ; Ruggeri, E. ; Omenetto, F.G. ; Hilgendorff, A. ; Schnabel, J.A. ; Schubert, B.
Colorimetric Sensor Reading and Illumination Correction via Multi-Task Deep-Learning.Wasnick, R. ; Korfei, M. ; Piskulak, K. ; Henneke, I. ; Wilhelm, J. ; Mahavadi, P. ; Dartsch, R.C. ; von der Beck, D. ; Koch, M. ; Shalashova, I. ; Weiss, A.R. ; Klymenko, O. ; Askevold, I. ; Fink, L. ; Witt, H. ; Hackstein, H. ; El Agha, E. ; Bellusci, S. ; Klepetko, W. ; Königshoff, M. ; Eickelberg, O. ; Schermuly, R.T. ; Braun, T. ; Seeger, W. ; Ruppert, C. ; Guenther, A.
Notch1 induces defective epithelial surfactant processing and pulmonary fibrosis.Mohanty, P. ; Panda, P. ; Acharya, R.K. ; Pande, B. ; Bhaskar, L. ; Verma, H.K.
Emerging perspectives on RNA virus-mediated infections: From pathogenesis to therapeutic interventions.De Sadeleer, L.J. ; Chen, Y. ; Jentzsch, R.C. ; Wang, Z. ; Qazi, N. ; Lang, N.J. ; Albanese, P. ; Jankevics, A. ; Theis, F.J. ; Scheltema, R.A. ; Wuyts, W.A. ; Gote-Schniering, J. ; Schiller, H.
Evolution of epithelial-mesenchymal cell circuits in the progression of pulmonary fibrosis.Chen, Y. ; Schniering, J. ; Müller, M. ; Albanese, P. ; Jankevics, A. ; Jentzsch, R.C. ; Tata, A. ; Ansari, M. ; De Sadeleer, L.J. ; Yang, L. ; Heumos, L. ; Agami, A. ; Zhou, S. ; Mayr, C. ; Hatz, R. ; Schneider, C.P. ; Behr, J. ; Hilgendorff, A. ; Yildirim, A.Ö. ; Stoleriu, M.G. ; Dorfmueller, P. ; Theis, F.J. ; Tata, P.R. ; Luecken, M. ; Scheltema, R.A. ; Schiller, H.
A spatially resolved extracellular matrix proteome atlas of the distal human lung.Häfner, F. ; Johansson, C. ; Schwarzkopf, L. ; Forster, K. ; Kraus, Y. ; Flemmer, A.W. ; Hansmann, G. ; Sallmon, H. ; Felderhoff-Müser, U. ; Witt, S. ; Schwettmann, L. ; Hilgendorff, A.
Current diagnosis and treatment practice for pulmonary hypertension in bronchopulmonary dysplasia-A survey study in Germany (PUsH BPD).Rambold, U. ; Sperling, S. ; Chew, Z. ; Wang, Y. ; Steer, B. ; Zeller, K. ; Strobl, L.J. ; Zimber-Strobl, U. ; Adler, H.
A mouse model to study the pathogenesis of γ-herpesviral infections in germinal center B cells.Mairhörmann, B. ; Castelblanco, A. ; Häfner, F. ; Koliogiannis, V. ; Haist, L. ; Winter, D. ; Flemmer, A.W. ; Ehrhardt, H. ; Stöcklein, S. ; Dietrich, O. ; Förster, K. ; Hilgendorff, A. ; Schubert, B.
Automated MRI lung segmentation and 3D morphologic features for quantification of neonatal lung disease.Staab-Weijnitz, C.A.
A NEAT discovery hints at altered golgi signaling in lung fibrosis.Lang, N.J. ; Schniering, J. ; Porras-Gonzalez, D.L. ; Yang, L. ; De Sadeleer, L.J. ; Jentzsch, R.C. ; Shitov, V.A. ; Zhou, S. ; Ansari, M. ; Agami, A. ; Mayr, C. ; Hooshiar Kashani, B. ; Chen, Y. ; Heumos, L. ; Pestoni, J. ; Molnar, E.S. ; Geeraerts, E. ; Anquetil, V. ; Saniere, L. ; Wögrath, M. ; Gerckens, M. ; Lehmann, M. ; Yildirim, A.Ö. ; Hatz, R.A. ; Kneidinger, N. ; Behr, J. ; Wuyts, W.A. ; Stoleriu, M.-G. ; Luecken, M. ; Theis, F.J. ; Burgstaller, G. ; Schiller, H.
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis.Verleden, S.E. ; Hendriks, J.M.H. ; Snoeckx, A. ; Mai, C. ; Mentens, Y. ; Callebaut, W. ; De Belie, B. ; Van Schil, P.E. ; Verplancke, V. ; Janssens, A.C. ; Jacob, J. ; Pakzad, A. ; Conlon, T.M. ; Guvenc, G. ; Yildirim, A.Ö. ; Pauwels, P. ; Koljenovic, S. ; Kwakkel-Van-Erp, J.M. ; Lapperre, T.
Small airways disease in Pre-COPD with emphysema: A cross-sectional study.Acharya, R. ; Mahapatra, A. ; Verma, H.K. ; Bhaskar, L.V.K.S.
Unveiling therapeutic targets for esophageal cancer: A comprehensive review.Kos, A. ; Lopez, J.P. ; Bordes, J. ; De Donno, C. ; Dine, J. ; Brivio, E. ; Karamihalev, S. ; Luecken, M. ; Almeida-Correa, S. ; Gasperoni, S. ; Dick, A. ; Miranda, L. ; Büttner, M. ; Stoffel, R. ; Flachskamm, C. ; Theis, F.J. ; Schmidt, M.V. ; Chen, A.
Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus.Paliwal, S.R. ; Sulakhiya, K. ; Kumar, P. ; Maiti, S. ; Paliwal, R.
Hormonal delivery systems.Doryab, A.
Bioinspirierte Lunge–auf–Chip als Alternative zu Tierversuchen.Mahapatra, A. ; Verma, H.K. ; Nag, S. ; Singh, S. ; Khattri, A. ; Bhaskar, L.V.K.S.
Advances in the molecular etiology of severe combined immunodeficiency and its screening.Jürgens, D.C. ; Deßloch, L. ; Porras-Gonzalez, D.L. ; Winkeljann, J. ; Zielinski, S. ; Munschauer, M. ; Hörner, A.L. ; Burgstaller, G. ; Winkeljann, B. ; Merkel, O.M.
Lab-scale siRNA and mRNA LNP manufacturing by various microfluidic mixing techniques – an evaluation of particle properties and efficiency.Bramey, N. ; Schmeck, B. ; Lehmann, M.
Aging and regeneration in the lung – Significance for COPD.Dilger, M. ; Armant, O. ; Ramme, L. ; Mülhopt, S. ; Sapcariu, S.C. ; Schlager, C. ; Dilger, E. ; Reda, A. ; Orasche, J. ; Schnelle-Kreis, J. ; Conlon, T.M. ; Yildirim, A.Ö. ; Hartwig, A. ; Zimmermann, R. ; Hiller, K. ; Diabaté, S. ; Paur, H.R. ; Weiss, C.
Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents.Häfner, F. ; Kindt, A.S.D. ; Strobl, K. ; Forster, K. ; Heydarian, M. ; Gonzalez-Rodriguez, E. ; Schubert, B. ; Kraus, Y. ; Robert, D.P. ; Flemmer, A.W. ; Ertl-Wagner, B. ; Dietrich, O. ; Stoecklein, S. ; Tello, K. ; Hilgendorff, A.
MRI pulmonary artery flow detects lung vascular pathology in preterms with lung disease.Wickramasinghe, L.C. ; Tsantikos, E. ; Kindt, A.S.D. ; Raftery, A.L. ; Gottschalk, T.A. ; Borger, J.G. ; Malhotra, A. ; Anderson, G.P. ; van Wijngaarden, P. ; Hilgendorff, A. ; Hibbs, M.L.
Granulocyte colony-stimulating factor is a determinant of severe bronchopulmonary dysplasia and coincident retinopathy.Kapellos, T. ; Conlon, T.M. ; Yildirim, A.Ö. ; Lehmann, M.
The impact of the immune system on lung injury and regeneration in COPD.Kurmi, B.D. ; Patel, P. ; Paliwal, R. ; Kumar, P. ; Paliwal, S.R.
Multifunctional nanotherapeutics for intracellular trafficking of doxorubicin against breast cancer.Jia, J. ; Marazioti, A. ; Voulgaridis, A. ; Psallidas, I. ; Lamort, A.-S. ; Iliopoulou, M. ; Krontira, A.C. ; Lilis, I. ; Asciak, R. ; Kanellakis, N.I. ; Rahman, N.M. ; Karkoulias, K. ; Spiropoulos, K. ; Liu, R. ; Kaiser, J.C. ; Stathopoulos, G.T.
Clinical identification of malignant pleural effusions.Tanabe, S. ; Beaton, D. ; Chauhan, V. ; Choi, I. ; Choi, J. ; Clerbaux, L.A. ; Coppola, L. ; Dumont, A.F. ; Esterhuizen, M. ; Filipovska, J. ; FitzGerald, R. ; Fritsche, E. ; Garcia-Reyero, N. ; Goralczyk, A. ; Huliganga, E. ; Kim, Y.J. ; Klose, J. ; La Rocca, C. ; Landesmann, B. ; Mally, A. ; Murugadoss, S. ; Omeragic, E. ; Ouédraogo, G. ; Pereira, J.M. ; Sadi, B. ; Schaffert, A. ; Song, Y. ; Sovadinova, I. ; Stöger, T. ; Tollefsen, K.E. ; Wittwehr, C. ; Yauk, C.
Report of the 3rd and 4th Mystery of Reactive Oxygen Species Conference.Leuschner, G. ; Semenova, A. ; Mayr, C. ; Kapellos, T. ; Ansari, M. ; Seeliger, B. ; Frankenberger, M. ; Kneidinger, N. ; Hatz, R.A. ; Hilgendorff, A. ; Prasse, A. ; Behr, J. ; Mann, M. ; Schiller, H.
Mass spectrometry-based autoimmune profiling reveals predictive autoantigens in idiopathic pulmonary fibrosis.Correa-Gallegos, D. ; Ye, H. ; Dasgupta, B. ; Sardogan, A. ; Kadri, S. ; Kandi, R. ; Dai, R. ; Lin, Y. ; Kopplin, R. ; Shantaram Shenai, D. ; Wannemacher, J. ; Ichijo, R. ; Jiang, D. ; Strunz, M. ; Ansari, M. ; Angelidis, I. ; Schiller, H. ; Voltz, T. ; Machens, H.G. ; Rinkevich, Y.
CD201+ fascia progenitors choreograph injury repair.Zhao, A. ; Gudmundsson, E. ; Mogulkoc, N. ; van Moorsel, C. ; Corte, T.J. ; Vasudev, P. ; Romei, C. ; Chapman, R. ; Wallis, T.J.M. ; Denneny, E. ; Goos, T. ; Savas, R. ; Ahmed, A. ; Brereton, C.J. ; van Es, H.W. ; Jo, H. ; De Liperi, A. ; Duncan, M. ; Pontoppidan, K. ; De Sadeleer, L.J. ; van Beek, F. ; Barnett, J. ; Cross, G. ; Procter, A. ; Veltkamp, M. ; Hopkins, P. ; Moodley, Y. ; Taliani, A. ; Taylor, M. ; Verleden, S. ; Tavanti, L. ; Vermant, M. ; Nair, A. ; Stewart, I. ; Janes, S.M. ; Young, A.L. ; Barber, D. ; Alexander, D.C. ; Porter, J.C. ; Wells, A.U. ; Jones, M.G. ; Wuyts, W.A. ; Jacob, J.
Mortality surrogates in combined pulmonary fibrosis and emphysema.Han, B. ; Lv, Y. ; Moser, D. ; Zhou, X. ; Woehrle, T. ; Han, L. ; Osterman, A. ; Rudelius, M. ; Choukér, A. ; Lei, P.
ACE2-independent SARS-CoV-2 virus entry through cell surface GRP78 on monocytes - evidence from a translational clinical and experimental approach.Bostancieri, N. ; Bakir, K. ; Kul, S. ; Eralp, A. ; Kayalar, Ö. ; Konyalilar, N. ; Rajabi, H. ; Yuncu, M. ; Yildirim, A.Ö. ; Bayram, H.
The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD.Schniering, J. ; Schiller, H. B.
Multilineage circuits of regenerative cell states.Han, L. ; Haefner, V. ; Yu, Y. ; Han, B. ; Ren, H. ; Irmler, M. ; Beckers, J. ; Liu, Q. ; Feuchtinger, A. ; Yildirim, A.Ö. ; Adler, H. ; Stöger, T.
Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice.Doryab, A. ; Heydarian, M. ; Yildirim, A.Ö. ; Hilgendorff, A. ; Behr, J. ; Schmid, O.
Breathing-induced stretch enhances the efficacy of an inhaled and orally delivered anti-fibrosis drug in vitro.Varaprasad, G.L. ; Gupta, V.K. ; Prasad, K. ; Kim, E. ; Tej, M.B. ; Mohanty, P. ; Verma, H.K. ; Raju, G.S.R. ; Bhaskar, L. ; Huh, Y.S.
Recent advances and future perspectives in the therapeutics of prostate cancer.Jeridi, A. ; Kapellos, T. ; Yildirim, A.Ö.
Fumarate hydratase: A new checkpoint of metabolic regulation in inflammatory macrophages.Hyams, Y. ; Rubin-Blum, M. ; Rosner, A. ; Brodsky, L. ; Rinkevich, Y. ; Rinkevich, B.
Physiological changes during torpor favor association with Endozoicomonas endosymbionts in the urochordate Botrylloides leachii.Han, Y. ; Georgii, E. ; Priego-Cubero, S. ; Wurm, C. ; Hüther, P. ; Huber, G. ; Koller, R. ; Becker, C. ; Durner, J. ; Lindermayr, C.
Arabidopsis histone deacetylase HD2A and HD2B regulate seed dormancy by repressing DELAY OF GERMINATION 1.Chen, J. ; Wang, X. ; Schmalen, A. ; Haines, S. ; Wolff, M. ; Ma, H. ; Zhang, H. ; Stoleriu, M.-G. ; Nowak, J. ; Nakayama, M. ; Bueno, M. ; Brands, J. ; Mora, A.L. ; Lee, J.S. ; Krauss-Etschmann, S. ; Dmitrieva, A. ; Frankenberger, M. ; Hofer, T.P. ; Nößner, E. ; Moosmann, A. ; Behr, J. ; Milger, K. ; Deeg, C.A. ; Staab-Weijnitz, C.A. ; Hauck, S.M. ; Adler, H. ; Goldmann, T. ; Gaede, K.I. ; Behrends, J. ; Kammerl, I.E. ; Meiners, S.
Antiviral CD8+T-cell immune responses are impaired by cigarette smoke and in COPD.Rosenberger, F.A. ; Thielert, M. ; Strauss, M.T. ; Schweizer, L. ; Ammar, C. ; Mädler, S.C. ; Metousis, A. ; Skowronek, P. ; Wahle, M. ; Madden, K. ; Schniering, J. ; Semenova, A. ; Schiller, H. ; Rodriguez, E. ; Nordmann, T.M. ; Mund, A. ; Mann, M.
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome.John, S. ; Müller, J.
Age structure, replicator equation, and the prisoner's dilemma.Schmalen, A. ; Kammerl, I.E. ; Meiners, S. ; Nößner, E. ; Deeg , C.A. ; Hauck, S.M.
A lysine residue at the C-terminus of MHC class I ligands correlates with low C-terminal proteasomal cleavage probability.Han, Y. ; Haouel, A. ; Georgii, E. ; Priego-Cubero, S. ; Wurm, C. ; Hemmler, D. ; Schmitt-Kopplin, P. ; Becker, C. ; Durner, J. ; Lindermayr, C.
Histone deacetylases HD2A and HD2B undergo feedback regulation by ABA and modulate drought tolerance via mediating ABA-induced transcriptional repression.Staab-Weijnitz, C.A. ; Onursal, C. ; Nambiar, D. ; Vanacore, R.
Assessment of collagen in translational models of lung research.Virshup, I. ; Bredikhin, D. ; Heumos, L. ; Palla, G. ; Sturm, G. ; Gayoso, A. ; Kats, I. ; Koutrouli, M. ; Berger, B. ; Pe'er, D. ; Regev, A. ; Teichmann, S.A. ; Finotello, F. ; Wolf, F.A. ; Yosef, N. ; Stegle, O. ; Theis, F.J.
The scverse project provides a computational ecosystem for single-cell omics data analysis.Spella, M. ; Ntaliarda, G. ; Skiadas, G. ; Lamort, A.-S. ; Vreka, M. ; Marazioti, A. ; Lilis, I. ; Bouloukou, E. ; Giotopoulou, G.A. ; Pepe, M. ; Weiss, S.A. ; Petrera, A. ; Hauck, S.M. ; Koch, I. ; Lindner, M. ; Hatz, R.A. ; Behr, J. ; Arendt, K.A.M. ; Giopanou, I. ; Brunn, D. ; Savai, R. ; Jenne, D. ; de Château, M. ; Yull, F.E. ; Blackwell, T.S. ; Stathopoulos, G.T.
Non-oncogene addiction of KRAS-mutant cancers to IL-1β via versican and mononuclear IKKβ.Windhorst, A.C. ; Heydarian, M. ; Schwarz, M. ; Oak, P. ; Forster, K. ; Frankenberger, M. ; Gonzalez-Rodriguez, E. ; Zhang, X. ; Ehrhardt, H. ; Hübener, C. ; Flemmer, A.W. ; Hossain, H. ; Stöger, T. ; Schulz, C. ; Hilgendorff, A.
Monocyte signature as a predictor of chronic lung disease in the preterm infant.Cuevas Ocaña, S. ; El-Merhie, N. ; Kuipers, M.E. ; Lehmann, M. ; Enes, S.R. ; Voss, C. ; Dean, L.S.N. ; Loxham, M. ; Boots, A.W. ; Cloonan, S.M. ; Greene, C.M. ; Heijink, I.H. ; Joannes, A. ; Mailleux, A.A. ; Mansouri, N. ; Reynaert, N.L. ; van der Does, A.M. ; Wagner, D. ; Ubags, N.
ERS International Congress 2022: Highlights from the Basic and Translational Science Assembly.Vornholz, L. ; Isay, S.E. ; Kurgyis, Z. ; Strobl, D.C. ; Loll, P. ; Mosa, M.H. ; Luecken, M. ; Sterr, M. ; Lickert, H. ; Winter, C. ; Greten, F.R. ; Farin, H.F. ; Theis, F.J. ; Ruland, J.
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy.Wang, X. ; Zhang, H. ; Wang, Y. ; Bramasole, L. ; Guo, K. ; Mourtada, F. ; Meul, T. ; Hu, Q. ; Viteri-Alvarez, V. ; Kammerl, I.E. ; Königshoff, M. ; Lehmann, M. ; Magg, T. ; Hauck, F. ; Fernandez, I.E. ; Meiners, S.
DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity.Windhorst, A.C. ; Heydarian, M. ; Schwarz, M. ; Oak, P. ; Forster, K. ; Frankenberger, M. ; Gonzalez-Rodriguez, E. ; Zhang, X. ; Ehrhardt, H. ; Hübener, C. ; Flemmer, A.W. ; Hossain, H. ; Stöger, T. ; Schulz, C. ; Hilgendorff, A.
Corrigendum: Monocyte signature as a predictor of chronic lung disease in the preterm infant.Rani, R. ; Raina, N. ; Sharma, A. ; Kumar, P. ; Tulli, H.S. ; Gupta, M.
Advancement in nanotechnology for treatment of rheumatoid arthritis: Scope and potential applications.Braakhuis, H.M. ; Gremmer, E.R. ; Bannuscher, A. ; Drasler, B. ; Keshavan, S. ; Rothen-Rutishauser, B. ; Birk, B. ; Verlohner, A. ; Landsiedel, R. ; Meldrum, K. ; Doak, S.H. ; Clift, M.J.D. ; Erdem, J.S. ; Foss, O.A.H. ; Zienolddiny-Narui, S. ; Serchi, T. ; Moschini, E. ; Weber, P. ; Burla, S. ; Kumar, P. ; Schmid, O. ; Zwart, E. ; Vermeulen, J.P. ; Vandebriel, R.J.
Transferability and reproducibility of exposed air-liquid interface co-culture lung models.Kastlmeier, M.T. ; Gonzalez-Rodriguez, E. ; Cabanis , P. ; Günther, E. ; König, A.-C. ; Han, L. ; Hauck, S.M. ; See, F. ; Asgharpour, S. ; Bukas, C. ; Burgstaller, G. ; Piraud, M. ; Lehmann, M. ; Hatz, R.A. ; Behr, J. ; Stöger, T. ; Hilgendorff, A. ; Voss, C.
Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures.Javitt, A. ; Shmueli, M.D. ; Kramer, M.P. ; Kolodziejczyk, A.A. ; Cohen, I.J. ; Radomir, L. ; Sheban, D. ; Kamer, I. ; Litchfield, K. ; Bab-Dinitz, E. ; Zadok, O. ; Neiens, V. ; Ulman, A. ; Wolf-Levy, H. ; Eisenberg-Lerner, A. ; Kacen, A. ; Alon, M. ; Rêgo, A.T. ; Stacher-Priehse, E. ; Lindner, M. ; Koch, I. ; Bar, J. ; Swanton, C. ; Samuels, Y. ; Levin, Y. ; da Fonseca, P.C.A. ; Elinav, E. ; Friedman, N. ; Meiners, S. ; Merbl, Y.
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.Szepesi, Á. ; Bakacsy, L. ; Fehér, A. ; Kovács, H. ; Pálfi, P. ; Poór, P. ; Szőllősi, R. ; Gondor, O.K. ; Janda, T. ; Szalai, G. ; Lindermayr, C. ; Szabados, L. ; Zsigmond, L.
L-aminoguanidine induces imbalance of ROS/RNS homeostasis and polyamine catabolism of tomato roots after short-term salt exposure.Beck, C. ; Ramanujam, D. ; Vaccarello, P. ; Widenmeyer, F. ; Feuerherd, M. ; Cheng, C.C. ; Bomhard, A. ; Abikeeva, T. ; Schädler, J. ; Sperhake, J.P. ; Graw, M. ; Safi, S. ; Hoffmann, H. ; Staab-Weijnitz, C.A. ; Rad, R. ; Protzer, U. ; Frischmuth, T. ; Engelhardt, S.
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.Momeni Larimi, M. ; Babamiri, A. ; Biglarian, M. ; Ramiar, A. ; Tabe, R. ; Inthavong, K. ; Farnoud, A.
Numerical and experimental analysis of drug inhalation in realistic human upper airway model.Heumos, L. ; Ehmele, P. ; Kuhn Cuellar, L. ; Menden, K. ; Miller, E. ; Lemke, S. ; Gabernet, G. ; Nahnsen, S.
mlf-core: A framework for deterministic machine learning.Heumos, L. ; Schaar, A. ; Lance, C. ; Litinetskaya, A. ; Drost, F. ; Zappia, L. ; Luecken, M. ; Strobl, D.C. ; Henao, J. ; Curion, F. ; Schiller, H. ; Theis, F.J.
Best practices for single-cell analysis across modalities.Sikkema, L. ; Ramirez Suastegui, C. ; Strobl, D.C. ; Gillett, T.E. ; Zappia, L. ; Madissoon, E. ; Markov, N.S. ; Zaragosi, L.E. ; Ji, Y. ; Ansari, M. ; Arguel, M.J. ; Apperloo, L. ; Banchero, M. ; Bécavin, C. ; Berg, M. ; Chichelnitskiy, E. ; Chung, M.I. ; Collin, A. ; Gay, A.C.A. ; Schniering, J. ; Hooshiar Kashani, B. ; Inecik, K. ; Jain, M. ; Kapellos, T. ; Kole, T.M. ; Leroy, S. ; Mayr, C. ; Oliver, A.J. ; von Papen, M. ; Peter, L. ; Taylor, C.J. ; Walzthoeni, T. ; Xu, C. ; Bui, L.T. ; De Donno, C. ; Dony, L. ; Faiz, A. ; Guo, M. ; Gutierrez, A.J. ; Heumos, L. ; Huang, N. ; Ibarra Del Rio, I.A. ; Jackson, N.D. ; Kadur Lakshminarasimha Murthy, P. ; Lotfollahi, M. ; Tabib, T. ; Talavera Lopez, C.N. ; Travaglini, K.J. ; Wilbrey-Clark, A. ; Worlock, K.B. ; Yoshida, M. ; van den Berge, M. ; Bossé, Y. ; Desai, T.J. ; Eickelberg, O. ; Kaminski, N. ; Krasnow, M.A. ; Lafyatis, R. ; Nikolić, M.Z. ; Powell, J.E. ; Rajagopal, J. ; Rojas, M. ; Rozenblatt-Rosen, O. ; Seibold, M.A. ; Sheppard, D. ; Shepherd, D.P. ; Sin, D.D. ; Timens, W. ; Tsankov, A.M. ; Whitsett, J. ; Xu, Y. ; Banovich, N.E. ; Barbry, P. ; Duong, T.E. ; Falk, C.S. ; Meyer, K.B. ; Kropski, J.A. ; Pe'er, D. ; Schiller, H. ; Tata, P.R. ; Schultze, J.L. ; Teichmann, S.A. ; Misharin, A.V. ; Nawijn, M.C. ; Luecken, M. ; Theis, F.J.
An integrated cell atlas of the lung in health and disease.Boraschi, D. ; Duschl, A. ; Lynch, I. ; Stöger, T.
Editorial: Exploring impacts of combined exposures to particles and chemicals on immune reactions across living organisms.Damirov, F. ; Stoleriu, M.-G. ; Manapov, F. ; Büsing, K. ; Michels, J.D. ; Preissler, G. ; Hatz, R. ; Hohenberger, P. ; Roessner, E.D.
Histology of the primary tumor correlates with false positivity of integrated 18F-FDG-PET/CT lymph node staging in resectable lung cancer patients.Saini, M. ; Schmidleitner, L. ; Moreno, H.D. ; Donato, E. ; Falcone, M. ; Bartsch, J. ; Klein, C. ; Vogel, V. ; Würth, R. ; Pfarr, N. ; Espinet, E. ; Lehmann, M. ; Königshoff, M. ; Reitberger, M. ; Haas, S. ; Graf, E. ; Schwarzmayr, T. ; Strom, T.M. ; Spaich, S. ; Sütterlin, M. ; Schneeweiss, A. ; Weichert, W. ; Schotta, G. ; Reichert, M. ; Aceto, N. ; Sprick, M.R. ; Trumpp, A. ; Scheel, C.
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer.Heydarian, M. ; Oak, P. ; Koschlig, M. ; Kamgari, N. ; Hagemann, M. ; Wjst, M. ; Hilgendorff, A.
Prenatal vitamin D supplementation mitigates inflammation-related alveolar remodeling in neonatal mice.Kapellos, T. ; Baßler, K. ; Fujii, W. ; Nalkurthi, C. ; Schaar, A. ; Bonaguro, L. ; Pecht, T. ; Galvao, I. ; Agrawal, S. ; Saglam, A. ; Dudkin, E. ; Frishberg, A. ; De Domenico, E. ; Horne, A. ; Donovan, C. ; Kim, R.Y. ; Gallego-Ortega, D. ; Gillett, T.E. ; Ansari, M. ; Schulte-Schrepping, J. ; Offermann, N. ; Antignano, I. ; Sivri, B. ; Lu, W. ; Eapen, M.S. ; van Uelft, M. ; Osei-Sarpong, C. ; van den Berge, M. ; Donker, H.C. ; Groen, H.J.M. ; Sohal, S.S. ; Klein, J. ; Schreiber, T. ; Feißt, A. ; Yildirim, A.Ö. ; Schiller, H. ; Nawijn, M.C. ; Becker, M. ; Händler, K. ; Beyer, M. ; Capasso, M. ; Ulas, T. ; Hasenauer, J. ; Pizarro, C. ; Theis, F.J. ; Hansbro, P.M. ; Skowasch, D. ; Schultze, J.
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.Kalgudde Gopal, S. ; Dai, R. ; Stefanska, A.M. ; Ansari, M. ; Zhao, J. ; Ramesh, P. ; Bagnoli, J.W. ; Correa-Gallegos, D. ; Lin, Y. ; Christ, S. ; Angelidis, I. ; Lupperger, V. ; Marr, C. ; Davies, L.C. ; Enard, W. ; Machens, H.G. ; Schiller, H. ; Jiang, D. ; Rinkevich, Y.
Wound infiltrating adipocytes are not myofibroblasts.Goos, T. ; Dubbeldam, A. ; Vermant, M. ; Gogaert, S. ; De Sadeleer, L.J. ; De Crem, N. ; De Langhe, E. ; Yserbyt, J. ; Weynand, B. ; Carlon, M.S. ; Verschakelen, J. ; Vermeer, S. ; Verleden, S.E. ; Wuyts, W.A.
Intrafamilial correlation and variability in the clinical evolution of pulmonary fibrosis.Almet, A.A. ; Yuan, H. ; Annusver, K. ; Ramos, R. ; Liu, Y. ; Wiedemann, J. ; Sorkin, D.H. ; Landén, N.X. ; Sonkoly, E. ; Haniffa, M. ; Nie, Q. ; Lichtenberger, B.M. ; Luecken, M. ; Andersen, B. ; Tsoi, L.C. ; Watt, F.M. ; Gudjonsson, J.E. ; Plikus, M.V. ; Kasper, M.
A Roadmap for a consensus human skin cell atlas and single-cell data standardization.Wjst, M. ; Wendtner, C.
High variability of COVID-19 case fatality rate in Germany.Conlon, T.M. ; Yildirim, A.Ö.
Oxysterol metabolism dictates macrophage influx during SARS-CoV-2 infection.Stoleriu, M.-G. ; Gerckens, M. ; Zimmermann, J. ; Schön, J. ; Damirov, F. ; Samm, N. ; Kovács, J. ; Stacher-Priehse, E. ; Kellerer, C. ; Jörres, R.A. ; Kauke, T. ; Ketscher, C. ; Grützner, U. ; Hatz, R.
Preoperative risk factors predict perioperative allogenic blood transfusion in patients undergoing primary lung cancer resections: a retrospective cohort study from a high-volume thoracic surgery center.Doryab, A. ; Groll, J.
Biomimetic in vitro lung models: Current challenges and future perspective.Nakayama, M. ; Marchi, H. ; Dmitrieva, A. ; Chakraborty, A. ; Merl-Pham, J. ; Hennen, E. ; Le Gleut, R. ; Ruppert, C. ; Guenther, A. ; Kahnert, K. ; Behr, J. ; Hilgendorff, A. ; Hauck, S.M. ; Adler, H. ; Staab-Weijnitz, C.A.
Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection.Farnoud, A. ; Tofighian, H. ; Baumann, I. ; Ahookhosh, K. ; Pourmehran, O. ; Cui, X. ; Heuveline, V. ; Song, C. ; Vreugde, S. ; Wormald, P.J. ; Menden, M.P. ; Schmid, O.
Numerical and machine Learning analysis of the parameters affecting the regionally delivered nasal dose of nano- and micro-sized aerosolized drugs.Kandil, R. ; Baldassi, D. ; Böhlen, S. ; Müller, J.T. ; Jürgens, D.C. ; Bargmann, T. ; Dehmel, S. ; Xie, Y. ; Mehta, A. ; Sewald, K. ; Merkel, O.M.
Targeted GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma.Kindt, A. ; Förster, K. ; Cochius-den Otter, S.C.M. ; Flemmer, A.W. ; Hauck, S.M. ; Flatley, A. ; Kamphuis, J. ; Karrasch, S. ; Behr, J. ; Franz, A. ; Härtel, C. ; Krumsiek, J. ; Tibboel, D. ; Hilgendorff, A.
Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia.Abdollahi, H. ; Nabaei, M. ; Ahookhosh, K. ; Babamiri, A. ; Farnoud, A.
Evaluating the Potential of Ellipsoidal Particles for Inhalation Therapy in Comparison to Spherical Particles.Van Eeckhoutte, H.P. ; Donovan, C. ; Kim, R.Y. ; Conlon, T.M. ; Ansari, M. ; Khan, H. ; Jayaraman, R. ; Hansbro, N.G. ; Dondelinger, Y. ; Delanghe, T. ; Beal, A.M. ; Geddes, B. ; Bertin, J. ; Berghe, T.V. ; De Volder, J. ; Maes, T. ; Vandenabeele, P. ; Vanaudenaerde, B.M. ; Deforce, D. ; Škevin, S. ; Van Nieuwerburgh, F. ; Verhamme, F.M. ; Joos, G.F. ; Idrees, S. ; Schiller, H. B. ; Yildirim, A.Ö. ; Faiz, A. ; Bertrand, M.J.M. ; Brusselle, G.G. ; Hansbro, P.M. ; Bracke, K.R.
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.Kastlmeier, M.T. ; Günther, E. ; Stöger, T. ; Voss, C.
Lung organoids for hazard assessment of nanomaterials.Silbernagel, E. ; Stacher-Priehse, E. ; Dinkel, J. ; Stepp, H. ; Gesierich, W. ; Lindner, M. ; Behr, J. ; Reichenberger, F.
Bronchoscopic probe-based confocal laser endomicroscopy to diagnose diffuse parenchymal lung diseases.Gabryś, H.S. ; Schniering, J. ; Brunner, M. ; Bogowicz, M. ; Blüthgen, C. ; Frauenfelder, T. ; Guckenberger, M. ; Maurer, B. ; Tanadini-Lang, S.
Transferability of radiomic signatures from experimental to human interstitial lung disease.Biener, L. ; Milger, K. ; Suhling, H. ; Korn, S. ; Pizarro, C. ; Skowasch, D.
Impact of short-term pausing of oral corticosteroids on blood eosinophil count in patients with severe asthma.Biglarian, M. ; MomeniLarimi, M. ; Firoozabadi, B. ; Inthavong, K. ; Farnoud, A.
Targeted drug delivery with polydisperse particle transport and deposition in patient-specific upper airway during inhalation and exhalation.Förster, K. ; Marchi, H. ; Stöcklein, S. ; Dietrich, O. ; Ehrhardt, H. ; Wielpütz, M.O. ; Flemmer, A.W. ; Schubert, B. ; Mall, M.A. ; Ertl-Wagner, B. ; Hilgendorff, A.
MRI based scoring of the diseased lung in the preterm infant with BPD.Bannuscher, A. ; Schmid, O. ; Drasler, B. ; Rohrbasser, A. ; Braakhuis, H.M. ; Meldrum, K. ; Zwart, E.P. ; Gremmer, E.R. ; Birk, B. ; Rissel, M. ; Moschini, E. ; Evans, S.J. ; Kumar, P. ; Orak, S. ; Doryab, A. ; Erdem, J.S. ; Serchi, T. ; Vandebriel, R.J. ; Cassee, F.R. ; Doak, S.H. ; Petri-Fink, A. ; Zienolddiny, S. ; Clift, M.J.D. ; Rothen-Rutishauser, B.
An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized materials.Zambusi, A. ; Novoselc, K.T. ; Hutten, S. ; Kalpazidou, S. ; Koupourtidou, C. ; Schieweck, R. ; Aschenbroich, S. ; Silva, L. ; Yazgili, A.S. ; van Bebber, F. ; Schmid, B. ; Möller, G. ; Tritscher, C. ; Stigloher, C. ; Delbridge, C. ; Sirko, S. ; Günes, Z.I. ; Liebscher, S. ; Schlegel, J. ; Aliee, H. ; Theis, F.J. ; Meiners, S. ; Kiebler, M. ; Dormann, D. ; Ninkovic, J.
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.Geiger, F. ; Zeitlmayr, S. ; Staab-Weijnitz, C.A. ; Rajan, S. ; Breit, A. ; Gudermann, T. ; Dietrich, A.
An inhibitory function of TRPA1 channels in TGF-β1-driven fibroblast to myofibroblast differentiation.Bauer, A. ; Pachl, E. ; Hellmuth, J.C. ; Kneidinger, N. ; Heydarian, M. ; Frankenberger, M. ; Stubbe, H.C. ; Ryffel, B. ; Petrera, A. ; Hauck, S.M. ; Behr, J. ; Kaiser, R. ; Scherer, C. ; Deng, L. ; Teupser, D. ; Ahmidi, N. ; Muenchhoff, M. ; Schubert, B. ; Hilgendorff, A.
Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients.Musiol, S. ; Harris, C. ; Karlina, R. ; Gostner, J.M. ; Rathkolb, B. ; Schnautz, B. ; Schneider, E. ; Mair, L. ; Vergara, E.E. ; Flexeder, C. ; Koletzko, S. ; Bauer, C.P. ; Schikowski, T. ; Berdel, D. ; von Berg, A. ; Herberth, G. ; Rozman, J. ; Hrabě de Angelis, M. ; Standl, M. ; Schmidt-Weber, C.B. ; Ussar, S. ; Alessandrini, F.
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice.Al-Samir, S. ; Yildirim, A.Ö. ; Sidhaye, V.K. ; King, L.S. ; Breves, G. ; Conlon, T.M. ; Stoeger, C. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Gros, G. ; Endeward, V.
Aqp5--/-- mice exhibit reduced maximal O2 consumption under cold exposure, normal pulmonary gas exchange, and impaired formation of brown adipose tissue.Verma, H.K. ; Ratre, Y.K. ; Bhaskar, L.V.K.S. ; Sahu, T. ; Lingojwar, D.P.
Hematopoietic stem cell transplant therapy, clinical trials, complications, and quality of life for patients with Sickle cell anemia: Clinical potential and future perspectives.Tiwari, R. ; Gulbake, A. ; Kumar, P. ; Gulbake, A.S. ; Gupta, R. ; Bisht, D. ; Sethiya, N.K.
Aptamer-based targeted drug delivery systems.Shin, H. ; Morty, R.E. ; Sucre, J.M.S. ; Negretti, N.M. ; Markmann, M. ; Hossain, H. ; Krauss-Etschmann, S. ; Dehmel, S. ; Hilgendorff, A.
Reference genes for the developing mouse lung under consideration of biological, technical and experimental confounders.Sahu, T. ; Verma, H.K. ; Lvks, B.
Management of SARS-CoV-2 infection is a major challenge in patients with lymphoid malignancies: Warrants a clear therapeutic strategy.Doryab, A. ; Schmid, O.
Towards a gold standard functional readout to characterize In Vitro lung barriers.Berthold, E. ; Ma-Lauer, Y. ; Chakraborty, A. ; von Brunn, B. ; Hilgendorff, A. ; Hatz, R.A. ; Behr, J. ; Hausch, F. ; Staab-Weijnitz, C.A. ; von Brunn, A.
Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models.Dehmel, S. ; Weiss, K. ; El-Merhie, N. ; Callegari, J. ; Konrad, B ; Mutze, K. ; Eickelberg, O. ; Königshoff, M. ; Krauss-Etschmann, S.
microRNA expression profile of purified alveolar epithelial type II cells.Xiong, K. ; Qi, M. ; Stöger, T. ; Zhang, J. ; Chen, S.
The role of tumor-associated macrophages and soluble mediators in pulmonary metastatic melanoma.Trassl, L. ; Stathopoulos, G.T.
KRAS pathway alterations in malignant pleural mesothelioma: An underestimated player.Förster, K. ; Haist, L. ; Hilgendorff, A.
Langzeitfolgen der chronischen neonatalen Lungenerkrankung. Frühe Veränderungen und spätere Indikatoren.Fischer, C. ; Jörres, R.A. ; Alter, P. ; Trudzinski, F.C. ; Yildirim, A.Ö. ; Bals, R. ; Vogelmeier, C.F. ; Kauffmann-Guerrero, D. ; Behr, J. ; Watz, H. ; Holle, R. ; Kahnert, K.
Basic determinants of disease knowledge in COPD patients: Results from COSYCONET.Doryab, A. ; Schmid, O.
Bioactive cell-derived ECM scaffold forms a unique cellular microenvironment for lung tissue engineering.Yazgili, A.S. ; Ebstein, F. ; Meiners, S.
The proteasome activator PA200/PSME4: An emerging new player in health and disease.Tschiche, H.R. ; Bierkandt, F.S. ; Creutzenberg, O. ; Fessard, V. ; Franz, R. ; Greiner, R. ; Gruber-Traub, C. ; Haas, K.H. ; Haase, A. ; Hartwig, A. ; Hesse, B.D. ; Hund-Rinke, K. ; Iden, P. ; Kromer, C. ; Löschner, K. ; Mutz, D. ; Rakow, A. ; Rasmussen, K. ; Rauscher, H. ; Richter, H. ; Schoon, J. ; Schmid, O. ; Som, C. ; Spindler, L.M. ; Tovar, G.E.M. ; Westerhoff, P. ; Wohlleben, W. ; Luch, A. ; Laux, P.
Analytical and toxicological aspects of nanomaterials in different product groups: Challenges and opportunities.Kessler, N. ; Viehmann, S.F. ; Krollmann, C. ; Mai, K. ; Kirschner, K.M. ; Luksch, H. ; Kotagiri, P. ; Böhner, A.M.C. ; Huugen, D. ; de Oliveira Mann, C.C. ; Otten, S. ; Weiss, S.A. ; Zillinger, T. ; Dobrikova, K. ; Jenne, D. ; Behrendt, R. ; Ablasser, A. ; Bartok, E. ; Hartmann, G. ; Hopfner, K.P. ; Lyons, P.A. ; Boor, P. ; Rosen-Wolff, A. ; Teichmann, L.L. ; Heeringa, P. ; Kurts, C. ; Garbi, N.
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.Chen, Y. ; Toth, R. ; Chocarro, S. ; Weichenhan, D. ; Hey, J. ; Lutsik, P. ; Sawall, S. ; Stathopoulos, G.T. ; Plass, C. ; Sotillo, R.
Club cells employ regeneration mechanisms during lung tumorigenesis.Kuhn, L. ; Valentin, S. ; Stojanovic, K. ; Strobl, D.C. ; Babushku, T. ; Wang, Y. ; Rambold, U. ; Scheffler, L. ; Grath, S. ; John-Robbert, D. ; Blum, H. ; Feuchtinger, A. ; Blutke, A. ; Weih, F. ; Kitamura, D. ; Rad, R. ; Strobl, L.J. ; Zimber-Strobl, U.
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.Kindt, A. ; Kraus, Y. ; Rasp, D. ; Förster, K. ; Ahmidi, N. ; Flemmer, A.W. ; Herber-Jonat, S. ; Heinen, F. ; Weigand, H. ; Hankemeier, T. ; Koletzko, B. ; Krumsiek, J. ; Babl, J. ; Hilgendorff, A.
Improved Macro- and micronutrient supply for favorable growth and metabolomic profile with standardized parenteral nutrition solutions for very preterm infants.Heydarian, M. ; Schulz, C. ; Stöger, T. ; Hilgendorff, A.
Association of immune cell recruitment and BPD development.Bush, A. ; Hilgendorff, A.
Editorial: Bronchopulmonary dysplasia: Past, current and future pathophysiologic concepts and their contribution to understanding lung disease.Zeitlmayr, S. ; Zierler, S. ; Staab-Weijnitz, C.A. ; Dietrich, A. ; Geiger, F. ; Horgen, F.D. ; Gudermann, T. ; Breit, A.
TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts.Mümmler, C. ; Suhling, H. ; Walter, J. ; Kneidinger, N. ; Buhl, R. ; Kayser, M.Z. ; Drick, N. ; Behr, J. ; Welte, T. ; Korn, S. ; Milger, K.
Overall response to anti-IL5/anti-IL5Rα treatment in severe asthma does not depend on initial bronchodilator responsiveness.Strieker, S. ; Weinmann, T. ; Gerlich, J. ; von Mutius, E. ; Nowak, D. ; Radon, K. ; Wengenroth, L.
Farm living and allergic rhinitis from childhood to young adulthood - prospective results of the GABRIEL study.Stoecklein, S. ; Koliogiannis, V. ; Prester, T. ; Kolben, T. ; Jegen, M. ; Hübener, C. ; Hasbargen, U. ; Flemmer, A. ; Dietrich, O. ; Schinner, R. ; Dinkel, J. ; Fink, N.R. ; Muenchhoff, M. ; Hintz, S. ; Delius, M. ; Mahner, S. ; Ricke, J. ; Hilgendorff, A.
Effects of SARS-CoV-2 on prenatal lung growth assessed by fetal MRI.Doryab, A. ; Taskin, M.B. ; Stahlhut, P. ; Groll, J. ; Schmid, O.
Real-time measurement of cell mechanics as a clinically relevant readout of an in vitro lung fibrosis model established on a bioinspired basement membrane.Zimmermann, C.M. ; Baldassi, D. ; Chan, K. ; Adams, N.B.P. ; Neumann, A. ; Porras-Gonzalez, D.L. ; Wei, X. ; Kneidinger, N. ; Stoleriu, M.G. ; Burgstaller, G. ; Witzigmann, D. ; Luciani, P. ; Merkel, O.M.
Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery.Panda, P. ; Verma, H.K. ; Lakkakula, S. ; Merchant, N. ; Kadir, F. ; Rahman, S. ; Jeffree, M.S. ; Lakkakula, B.V.K.S. ; Rao, P.V.
Biomarkers of oxidative stress tethered to cardiovascular diseases.Alessandrini, F. ; de Jong, R.J. ; Wimmer, M. ; Maier, A.-M. ; Fernandez, I.E. ; Hils, M. ; Buters, J.T.M. ; Biedermann, T. ; Zissler, U.M. ; Hoffmann, C. ; Esser-von Bieren, J. ; Schmidt-Weber, C.B. ; Ohnmacht, C.
Lung epithelial CYP1 activity regulates aryl hydrocarbon receptor dependent allergic airway inflammation.Ikonomou, L. ; Magnusson, M. ; Dries, R. ; Herzog, E.L. ; Hynds, R. ; Borok, Z. ; Park, J.A. ; Skolasinski, S. ; Burgess, J.K. ; Turner, L. ; Mojarad, S.M. ; Mahoney, J.E. ; Lynch, T. ; Lehmann, M. ; Thannickal, V.J. ; Hook, J.L. ; Vaughan, A.E. ; Hoffman, E.T. ; Weiss, D.J. ; Ryan, A.L.
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021.Schlesser, C. ; Meul, T. ; Stathopoulos, G.T. ; Meiners, S.
Metformin induces resistance of cancer cells to the proteasome inhibitor bortezomib.Verma, H.K. ; Prasad, K. ; Kumar, P. ; Lvks, B.
Viral hepatitis: A global burden needs future directions for the management.Bal, C. ; Idzko, M. ; Škrgat, S. ; Koch, A. ; Milger, K. ; Schulz, C. ; Zehetmayer, S. ; Hamelmann, E. ; Buhl, R. ; Korn, S.
Fraction of exhaled nitric oxide is associated with disease burden in the German Asthma Net severe asthma cohort.Tiwari, A. ; Gulbake, A.S. ; Kumar, P.
Lipid nanoparticles and nanoemulsions exploited in the diagnosis and treatment of infectious diseases.Mirastschijski, U. ; Jiang, D. ; Rinkevich, Y.
Genital wound repair and scarring.Krick, S. ; Geraghty, P. ; Jourdan Le Saux, C. ; Rojas, M. ; Staab-Weijnitz, C.A.
Editorial: Defining and characterizing respiratory disease in an aging population.Leroux, M.M. ; Hocquel, R. ; Bourge, K. ; Kokot, B. ; Kokot, H. ; Koklič, T. ; Štrancar, J. ; Ding, Y. ; Kumar, P. ; Schmid, O. ; Rihn, B.H. ; Ferrari, L. ; Joubert, O.
Aerosol–cell exposure system applied to semi-adherent cells for aerosolization of lung surfactant and nanoparticles followed by high quality RNA extraction.Preisendörfer, S. ; Ishikawa, Y. ; Hennen, E. ; Winklmeier, S. ; Schupp, J.C. ; Knüppel, L. ; Fernandez, I.E. ; Binzenhöfer, L. ; Flatley, A. ; Juan-Guardela, B.M. ; Ruppert, C. ; Guenther, A. ; Frankenberger, M. ; Hatz, R.A. ; Kneidinger, N. ; Behr, J. ; Feederle, R. ; Schepers, A. ; Hilgendorff, A. ; Kaminski, N. ; Meinl, E. ; Bächinger, H.P. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FK506-binding protein 11 is a novel plasma cell-specific antibody folding catalyst with increased expression in idiopathic pulmonary fibrosis.Sahu, T. ; Verma, H.K. ; Bhaskar, L.V.K.S.
Bacterial and fungal co-infection is a major barrier in COVID-19 patients: A specific management and therapeutic strategy is required.Shahzad, T. ; Chao, C.M. ; Hadzic, S. ; Behnke, J. ; Biebach, L. ; Boettcher-Friebertshaeuser, E. ; Wilhelm, J. ; Hilgendorff, A. ; Zimmer, K. ; Morty, R.E. ; Bellusci, S. ; Ehrhardt, H.
TRAIL protects the immature lung from hyperoxic injury.Schmidt, F. ; Nowak, L. ; Obereisenbuchler, F. ; Hetrodt, J. ; Heiß-Neumann, M. ; Schönlebe, A. ; Heinig-Menhard, K. ; Gesierich, W. ; Behr, J. ; Hatz, R.A. ; Dinkel, J. ; Stoleriu, M.-G.
Predicting the effectiveness of high-flow oxygen therapy in COVID-19 patients: A single-centre observational study.Secher, T. ; Bodier-Montagutelli, E. ; Parent, C. ; Bouvart, L. ; Cortes, M. ; Ferreira, M.A. ; Macloughlin, R. ; Ilango, G. ; Schmid, O. ; Respaud, R. ; Heuzé-Vourc’h, N.
Aggregates associated with instability of antibodies during aerosolization induce adverse immunological effects.Sahu, T. ; Pande, B. ; Sinha, M. ; Sinha, R. ; Verma, H.K.
Neurocognitive changes in sickle cell disease: A comprehensive review.Chakraborty, A. ; Mastalerz, M. ; Ansari, M. ; Schiller, H. B. ; Staab-Weijnitz, C.A.
Emerging roles of airway epithelial cells in idiopathic pulmonary fibrosis.Cheng, S. ; Liu, X. ; Mu, J. ; Yan, W. ; Wang, M. ; Chai, H. ; Sha, Y. ; Jiang, S. ; Wang, S. ; Ren, Y. ; Gao, C. ; Ding, Z. ; Stöger, T. ; Tseren-Ochir, E.O. ; Dodovski, A. ; Alfonso, P. ; Mingala, C.N. ; Yin, R.
Intense innate immune responses and severe metabolic disorders in chicken embryonic visceral tissues caused by infection with highly virulent newcastle disease virus compared to the avirulent virus: A bioinformatics analysis.Tschiche, H.R. ; Bierkandt, F.S. ; Creutzenberg, O. ; Fessard, V. ; Franz, R. ; Giese, B. ; Greiner, R. ; Haas, K.H. ; Haase, A. ; Hartwig, A. ; Hund‑Rinke, K. ; Iden, P. ; Kromer, C. ; Loeschner, K. ; Mutz, D. ; Rakow, A. ; Rasmussen, K. ; Rauscher, H. ; Richter, H. ; Schoon, J. ; Schmid, O. ; Som, C. ; Günter, G.E. ; Westerhoff, P. ; Wohlleben, W. ; Luch, A. ; Laux, P.
Environmental considerations and current status of grouping and regulation of engineered nanomaterials.Correa-Gallegos, D. ; Machens, H.G. ; Rinkevich, Y.
States and fates of skin fibroblasts revealed through chromatin accessibility.Arendt, K.A.M. ; Ntaliarda, G. ; Armenis, V. ; Kati, D. ; Henning, C. ; Giotopoulou, G.A. ; Pepe, M. ; Klotz, L.V. ; Lamort, A.-S. ; Hatz, R.A. ; Kobold, S. ; Schamberger, A.C. ; Stathopoulos, G.T.
An in vivo inflammatory loop potentiates KRAS blockade.Lehmann, M. ; Rojas, M.
IPF: Let's keep the focus on the A(ge)TII cell.Padhi, U.N. ; Mulkalwar, M. ; Saikrishna, L. ; Verma, H.K. ; Bhaskar, L.
NOS3 gene intron 4 a/b polymorphism is associated with ESRD in autosomal dominant polycystic kidney disease patients.Heinzelmann, K. ; Hu, Q. ; Hu, Y. ; Dobrinskikh, E. ; Ansari, M. ; Melo-Narváez, C. ; Ulke, H.M. ; Leavitt, C. ; Mirita, C. ; Trudeau, T. ; Saal, M.L. ; Rice, P. ; Gao, B. ; Janssen, W.J. ; Yang, I.V. ; Schiller, H. B. ; Vladar, E.K. ; Lehmann, M. ; Königshoff, M.
Single cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis.Schniering, J. ; Maciukiewicz, M. ; Tanadini-Lang, S. ; Maurer, B.
Reply to: The potential and challenges of radiomics in uncovering prognostic and molecular differences in interstitial lung disease associated with systemic sclerosis.Lommatzsch, M. ; Suhling, H. ; Korn, S. ; Bergmann, K.C. ; Schreiber, J. ; Bahmer, T. ; Rabe, K.F. ; Buhl, R. ; Virchow, J.C. ; Milger, K.
Safety of combining biologics in severe asthma: Asthma-related and unrelated combinations.Ren, L. ; Wang, L. ; Rehberg, M. ; Stöger, T. ; Zhang, J. ; Chen, S.
Applications and immunological effects of quantum dots on respiratory system.Spix, B. ; Jeridi, A. ; Ansari, M. ; Yildirim, A.Ö. ; Schiller, H. B. ; Grimm, C.
Endolysosomal cation channels and lung disease.Nikolova, S. ; Guenther, A. ; Savai, R. ; Weissmann, N. ; Ghofrani, H.A. ; Königshoff, M. ; Eickelberg, O. ; Klepetko, W. ; Voswinckel, R. ; Seeger, W. ; Grimminger, F. ; Schermuly, R.T. ; Pullamsetti, S.S.
Correction to: Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.Heydarian, M. ; Oak, P. ; Zhang, X. ; Kamgari, N. ; Kindt, A.S.D. ; Koschlig, M. ; Pritzke, T. ; Gonzalez-Rodriguez, E. ; Förster, K. ; Morty, R.E. ; Häfner, F. ; Hübener, C. ; Flemmer, A.W. ; Yildirim, A.Ö. ; Sudheendra, D. ; Tian, X. ; Petrera, A. ; Kirsten, H. ; Ahnert, P. ; Morrell, N. ; Desai, T.J. ; Sucre, J. ; Spiekerkoetter, E. ; Hilgendorff, A.
Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant.Liu, H. ; Hollauer, C. ; Hagl, C. ; Michel, S. ; Yildirim, A.Ö. ; Dashkevich, A.
Prolonged cold ischemia and indirect alloimmunity are fundamental for the development of chronic lung allograft dysfunction.Baldassi, D. ; Ambike, S. ; Feuerherd, M. ; Cheng, C.-C. ; Peeler, D.J. ; Feldmann, D.P. ; Porras-Gonzalez, D.L. ; Wei, X. ; Keller, L.A. ; Kneidinger, N. ; Stoleriu, M.G. ; Popp, A. ; Burgstaller, G. ; Pun, S.H. ; Michler, T. ; Merkel, O.M.
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.Günsel, G.G. ; Conlon, T.M. ; Jeridi, A. ; Kim, R. ; Ertüz, Z. ; Lang, N.J. ; Ansari, M. ; Novikova, M. ; Jiang, D. ; Strunz, M. ; Gaianova, M. ; Hollauer, C. ; Gabriel, C. ; Angelidis, I. ; Doll, S. ; Pestoni, J. ; Edelmann, S.L. ; Kohlhepp, M.S. ; Guillot, A. ; Bassler, K. ; Van Eeckhoutte, H.P. ; Kayalar, Ö. ; Konyalilar, N. ; Kanashova, T. ; Rodius, S. ; Ballester-Lopez, C. ; Genes Robles, C.M. ; Smirnova, N.F. ; Rehberg, M. ; Agarwal, C. ; Krikki, I. ; Piavaux, B. ; Verleden, S.E. ; Vanaudenaerde, B. ; Königshoff, M. ; Dittmar, G. ; Bracke, K.R. ; Schultze, J.L. ; Watz, H. ; Eickelberg, O. ; Stöger, T. ; Burgstaller, G. ; Tacke, F. ; Heissmeyer, V. ; Rinkevich, Y. ; Bayram, H. ; Schiller, H. B. ; Conrad, M. ; Schneider, R. ; Yildirim, A.Ö.
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.Wu, X. ; Bos, I.S.T. ; Conlon, T.M. ; Ansari, M. ; Verschut, V. ; van der Koog, L. ; Verkleij, L.A. ; D'Ambrosi, A. ; Matveyenko, A. ; Schiller, H. B. ; Königshoff, M. ; Schmidt, M. ; Kistemaker, L.E.M. ; Yildirim, A.Ö. ; Gosens, R.
A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration.Luecken, M. ; Zaragosi, L.E. ; Madissoon, E. ; Sikkema, L. ; Firsova, A.B. ; De Domenico, E. ; Kuemmerle, L. ; Saglam, A. ; Berg, M. ; Gay, A.C.A. ; Schniering, J. ; Mayr, C. ; Abalo, X.M. ; Larsson, L. ; Sountoulidis, A. ; Teichmann, S. ; van Eunen, K. ; Koppelman, G.H. ; Saeb-Parsy, K. ; Leroy, S. ; Powell, P. ; Sarkans, U. ; Timens, W. ; Lundeberg, J. ; van den Berge, M. ; Nilsson, M. ; Horváth, P. ; Denning, J. ; Papatheodorou, I. ; Schultze, J.L. ; Schiller, H. B. ; Barbry, P. ; Petoukhov, I. ; Misharin, A.V. ; Adcock, I. ; von Papen, M. ; Theis, F.J. ; Samakovlis, C. ; Meyer, K.B. ; Nawijn, M.C.
The discovAIR project: A roadmap towards the Human Lung Cell Atlas.Lange, M. ; Bergen, V. ; Klein, M. ; Setty, M. ; Reuter, B. ; Bakhti, M. ; Lickert, H. ; Ansari, M. ; Schniering, J. ; Schiller, H. B. ; Pe'er, D. ; Theis, F.J.
CellRank for directed single-cell fate mapping.Spix, B. ; Butz, E.S. ; Chen, C.C. ; Rosato, A.S. ; Tang, R. ; Jeridi, A. ; Kudrina, V. ; Plesch, E. ; Wartenberg, P. ; Arlt, E. ; Briukhovetska, D. ; Ansari, M. ; Günsel, G.G. ; Conlon, T.M. ; Wyatt, A. ; Wetzel, S. ; Teupser, D. ; Holdt, L.M. ; Ectors, F. ; Boekhoff, I. ; Boehm, U. ; García-Añoveros, J. ; Saftig, P. ; Giera, M. ; Kobold, S. ; Schiller, H. B. ; Zierler, S. ; Gudermann, T. ; Wahl-Schott, C. ; Bracher, F. ; Yildirim, A.Ö. ; Biel, M. ; Grimm, C.
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.Ambike, S. ; Cheng, C.-C. ; Feuerherd, M. ; Velkov, S. ; Baldassi, D. ; Afridi, S.Q. ; Porras-Gonzalez, D.L. ; Wei, X. ; Hagen, P. ; Kneidinger, N. ; Stoleriu, M.G. ; Grass, V. ; Burgstaller, G. ; Pichlmair, A. ; Merkel, O.M. ; Ko, C. ; Michler, T.
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.Sedaghat, M.H. ; Farnoud, A. ; Schmid, O. ; Abouali, O.
Nonlinear simulation of mucociliary clearance: A three- dimensional study.Staab-Weijnitz, C.A.
Fighting the fiber: Targeting collagen in lung fibrosis.Ihantola, T. ; Hirvonen, M.R. ; Ihalainen, M. ; Hakkarainen, H. ; Sippula, O. ; Tissari, J. ; Bauer, S. ; Di Bucchianico, S. ; Rastak, N. ; Hartikainen, A. ; Leskinen, J. ; Yli-Pirilä, P. ; Martikainen, M.V. ; Miettinen, M. ; Suhonen, H. ; Rönkkö, T.J. ; Kortelainen, M. ; Lamberg, H. ; Czech, H. ; Martens, P. ; Orasche, J. ; Michalke, B. ; Yildirim, A.Ö. ; Jokiniemi, J. ; Zimmermann, R. ; Jalava, P.I.
Genotoxic and inflammatory effects of spruce and brown coal briquettes combustion aerosols on lung cells at the air-liquid interface.Immler, R. ; Nadolni, W. ; Bertsch, A. ; Morikis, V. ; Rohwedder, I. ; Masgrau-Alsina, S. ; Schroll, T. ; Yevtushenko, A. ; Soehnlein, O. ; Moser, M. ; Gudermann, T. ; Barnea, E.R. ; Rehberg, M. ; Simon, S.I. ; Zierler, S. ; Pruenster, M. ; Sperandio, M.
The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation.Bondesson, D. ; Meijers, A. ; Janssens, G. ; Rit, S. ; Rabe, M. ; Kamp, F. ; Niepel, K. ; Otter, L.A.D. ; Both, S. ; Brousmiche, S. ; Dinkel, J. ; Belka, C. ; Parodi, K. ; Knopf, A. ; Kurz, C. ; Landry, G.
Anthropomorphic lung phantom based validation of in-room proton therapy 4D-CBCT image correction for dose calculation.Abdollahi, H. ; Babamiri, A. ; Ahookhosh, K. ; Farnoud, A. ; Nabaei, M.
Effects of Inhalation Flow Rate on Particle Deposition and Flow Structure in a Model of Tracheobronchial Airway.Lamort, A.-S. ; Kaiser, J.C. ; Pepe, M. ; Lilis, I. ; Ntaliarda, G. ; Somogyi, K. ; Spella, M. ; Behrend, S.J. ; Giotopoulou, G.A. ; Kujawa, W. ; Lindner, M. ; Koch, I. ; Hatz, R.A. ; Behr, J. ; Sotillo, R. ; Schamberger, A.C. ; Stathopoulos, G.T.
Prognostic phenotypes of early-stage lung adenocarcinoma.Paliwal, R. ; Kumar, P. ; Chaurasiya, A. ; Kenwat, R. ; Katke, S. ; Paliwal, S.R.
Development of nanomedicines and nano-similars: Recent advances in regulatory landscape.Purohit, M.R. ; Saikrishna, L. ; Verma, H.K. ; Bhaskar, L.V.K.S. ; Hussain, S.A.
Association between MTHFD1 1958G > A variant and non-syndromic cleft lip and palate: An updated meta-analysis.Verma, H.K. ; Bhaskar, L.
SARS-CoV-2 infection in people with pre-existing liver disease: Further research is warranted.Verma, H.K. ; Bhaskar, L.V.K.S.
Gender differences in the relationship between alcohol consumption and gastric cancer risk are uncertain and not well-delineated.Kratzel, A. ; Kelly, J.N. ; V'kovski, P. ; Portmann, J. ; Brüggemann, Y. ; Todt, D. ; Ebert, N. ; Shrestha, N. ; Plattet, P. ; Staab-Weijnitz, C.A. ; von Brunn, A. ; Steinmann, E. ; Dijkman, R. ; Zimmer, G. ; Pfaender, S. ; Thiel, V.
A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets.Gerckens, M. ; Schorpp, K.K. ; Pelizza, F. ; Wögrath, M. ; Reichau, K. ; Ma, H. ; Dworsky, A.-M. ; Sengupta, A. ; Stoleriu, M.-G. ; Heinzelmann, K. ; Merl-Pham, J. ; Irmler, M. ; Alsafadi, H.N. ; Trenkenschuh, E. ; Sarnova, L. ; Jirouskova, M. ; Frieß, W. ; Hauck, S.M. ; Beckers, J. ; Kneidinger, N. ; Behr, J. ; Hilgendorff, A. ; Hadian, K. ; Lindner, M. ; Königshoff, M. ; Eickelberg, O. ; Gregor, M. ; Plettenburg, O. ; Yildirim, A.Ö. ; Burgstaller, G.
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.Kammerl, I.E. ; Flexeder, C. ; Karrasch, S. ; Thorand, B. ; Heier, M. ; Peters, A. ; Schulz, H. ; Meiners, S.
Blood immunoproteasome activity is regulated by sex, age and in chronic inflammatory diseases: A first population-based study.Marazioti, A. ; Krontira, A.C. ; Behrend, S.J. ; Giotopoulou, G.A. ; Ntaliarda, G. ; Blanquart, C. ; Bayram, H. ; Iliopoulou, M. ; Vreka, M. ; Trassl, L. ; Pepe, M. ; Hackl, C.M. ; Klotz, L.V. ; Weiss, S.A. ; Koch, I. ; Lindner, M. ; Hatz, R.A. ; Behr, J. ; Wagner, D.E. ; Papadaki, H. ; Antimisiaris, S.G. ; Jean, D. ; Deshayes, S. ; Grégoire, M. ; Kayalar, ; Mortazavi, D. ; Dilege, ; Tanju, S. ; Erus, S. ; Yavuz, Ö. ; Bulutay, P. ; Fırat, P. ; Psallidas, I. ; Spella, M. ; Giopanou, I. ; Lilis, I. ; Lamort, A.-S. ; Stathopoulos, G.T.
KRAS signaling in malignant pleural mesothelioma.Chen, B. ; Yadav, M. ; Mulkalwar, M. ; Saikrishna, L. ; Verma, H.K. ; Ye, W. ; Bhaskar, L.V.K.S.
Meta-analysis on the association of neuropeptide Y rs16139 variant with the risk of alcoholism.Behr, J. ; Prasse, A. ; Kreuter, M. ; Johow, J. ; Rabe, K.F. ; Bonella, F. ; Bonnet, R. ; Grohe, C. ; Held, M. ; Wilkens, H. ; Hammerl, P. ; Koschel, D. ; Blaas, S. ; Wirtz, H. ; Ficker, J.H. ; Neumeister, W. ; Schoenfeld, N. ; Claussen, M. ; Kneidinger, N. ; Frankenberger, M. ; Hummler, S. ; Kahn, N. ; Tello, S. ; Freise, J. ; Welte, T. ; Neuser, P. ; Guenther, A.
Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): A double-blind, randomised, placebo-controlled, phase 2b trial.Qarri, A. ; Rinkevich, Y. ; Rinkevich, B.
Employing marine invertebrate cell culture media for isolation and cultivation of thraustochytrids.Mastalerz, M. ; Dick, E. ; Chakraborty, A. ; Hennen, E. ; Schamberger, A.C. ; Schröppel, A. ; Lindner, M. ; Hatz, R.A. ; Behr, J. ; Hilgendorff, A. ; Schmid, O. ; Staab-Weijnitz, C.A.
Validation of in vitro models for smoke exposure of primary human bronchial epithelial cells.Farnoud, A. ; Tofighian, H. ; Baumann, I. ; Martin, A.R. ; Rashidi, M.M. ; Menden, M.P. ; Schmid, O.
Pulsatile bi-directional aerosol flow affects aerosol delivery to the intranasal olfactory region: A patient-specific computational studyWinheim, E. ; Rinke, L. ; Lutz, K. ; Reischer, A. ; Leutbecher, A. ; Wolfram, L. ; Rausch, L. ; Kranich, J. ; Wratil, P.R. ; Huber, J.E. ; Baumjohann, D. ; Rothenfußer, S. ; Schubert, B. ; Hilgendorff, A. ; Hellmuth, J.C. ; Scherer, C. ; Muenchhoff, M. ; von Bergwelt-Baildon, M. ; Stark, K. ; Straub, T. ; Brocker, T. ; Keppler, O.T. ; Subklewe, M. ; Krug, A.B.
Impaired function and delayed regeneration of dendritic cells in COVID-19.Hoeper, M.M. ; Pausch, C. ; Olsson, K.M. ; Huscher, D. ; Pittrow, D. ; Grünig, E. ; Staehler, G. ; Vizza, C.D. ; Gall, H. ; Distler, O. ; Opitz, C. ; Gibbs, J.S.R. ; Delcroix, M. ; Ghofrani, H.A. ; Park, D.H. ; Ewert, R. ; Kaemmerer, H. ; Kabitz, H.J. ; Skowasch, D. ; Behr, J. ; Milger, K. ; Halank, M. ; Wilkens, H. ; Seyfarth, H.J. ; Held, M. ; Dumitrescu, D. ; Tsangaris, I. ; Vonk-Noordegraaf, A. ; Ulrich, S. ; Klose, H. ; Claussen, M. ; Lange, T.J. ; Rosenkranz, S.
COMPERA 2.0: A refined 4-strata risk assessment model for pulmonary arterial hypertension.Danielsen, P.H. ; Bendtsen, K.M. ; Knudsen, K.B. ; Poulsen, S.S. ; Stöger, T. ; Vogel, U.
Nanomaterial- and shape-dependency of TLR2 and TLR4 mediated signaling following pulmonary exposure to carbonaceous nanomaterials in mice.Shao, T. ; Verma, H.K. ; Pande, B. ; Costanzo, V. ; Ye, W. ; Cai, Y. ; Bhaskar, L.V.K.S.
Physical activity and nutritional influence on immune function: An important strategy to improve immunity and health status.Korkmaz, B. ; Lamort, A.-S. ; Domain, R. ; Beauvillain, C. ; Gieldon, A. ; Yildirim, A.Ö. ; Stathopoulos, G.T. ; Rhimi, M. ; Jenne, D. ; Kettritz, R.
Cathepsin C inhibition as a potential treatment strategy in cancer.Behrend, S.J. ; Giotopoulou, G.A. ; Spella, M. ; Stathopoulos, G.T.
A role for club cells in smoking-associated lung adenocarcinoma.Jahangiri, D. ; Padhi, U.N. ; Verma, H.K. ; Lakkakula, B.V. ; Valizadeh, R. ; Nasri, H.
Sodium-glucose co-transporter 2 inhibitors (SGLT2i); as a preventive factor of kidney failure in patients with type 2 diabetes; a meta-analysis of randomized controlled trials.Kammerl, I.E. ; Hardy, S. ; Flexeder, C. ; Urmann, A. ; Peierl, J. ; Wang, Y. ; Vosyka, O. ; Frankenberger, M. ; Milger, K. ; Behr, J. ; Koch, A. ; Merl-Pham, J. ; Hauck, S.M. ; Pilette, C. ; Schulz, H. ; Meiners, S.
Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients - implications for therapy.Schniering, J. ; Maciukiewicz, M. ; Gabryś, H.S. ; Brunner, M. ; Blüthgen, C. ; Meier, C. ; Braga-Lagache, S. ; Uldry, A.C. ; Heller, M. ; Guckenberger, M. ; Fretheim, H. ; Nakas, C.T. ; Hoffmann-Vold, A.M. ; Distler, O. ; Frauenfelder, T. ; Tanadini-Lang, S. ; Maurer, B.
Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis.Maan, Z.N. ; Rinkevich, Y. ; Barrera, J. ; Chen, K. ; Henn, D. ; Foster, D. ; Bonham, C.A. ; Padmanabhan, J. ; Sivaraj, D. ; Duscher, D. ; Hu, M. ; Yan, K. ; Januszyk, M. ; Longaker, M.T. ; Weissman, I.L. ; Gurtner, G.C.
Epidermal-derived hedgehog signaling drives mesenchymal proliferation during digit tip regeneration.Güney, T. ; Herranz, A.M. ; Mumby, S. ; Dunlop, I.E. ; Adcock, I.M.
Epithelial-stromal cell interactions and extracellular matrix mechanics drive the formation of airway-mimetic tubular morphology in lung organoids.van der Vorst, E.P.C. ; Pepe, M. ; Peters, L.J.F. ; Haberbosch, M. ; Jansen, Y. ; Naumann, R. ; Stathopoulos, G.T. ; Weber, C. ; Bidzhekov, K.
Correction to: Transcriptome signature of miRNA-26b KO mouse model suggests novel targets.Jiang, D. ; Rinkevich, Y.
Converting fibroblastic fates leads to wound healing without scar.Taheri, M.H. ; Pourmehran, O. ; Sarafraz, M.M. ; Ahookhosh, K. ; Farnoud, A. ; Cui, X.
Effect of swirling flow and particle-release pattern on drug delivery to human tracheobronchial airways.Briegel, I. ; Felicio-Briegel, A. ; Mertsch, P. ; Kneidinger, N. ; Haubner, F. ; Milger, K.
Hypereosinophilia with systemic manifestations under dupilumab and possibility of dual benralizumab and dupilumab therapy in patients with asthma and CRSwNP.Kaiser, R. ; Leunig, A. ; Pekayvaz, K. ; Popp, O. ; Joppich, M. ; Polewka, V. ; Escaig, R. ; Anjum, A. ; Hoffknecht, M.L. ; Gold, C. ; Brambs, S. ; Engel, A. ; Stockhausen, S. ; Knottenberg, V. ; Titova, A. ; Haji, M. ; Scherer, C. ; Muenchhoff, M. ; Hellmuth, J.C. ; Saar, K. ; Schubert, B. ; Hilgendorff, A. ; Schulz, C. ; Kääb, S. ; Zimmer, R. ; Hübner, N. ; Massberg, S. ; Mertins, P. ; Nicolai, L. ; Stark, K.
Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.Zhang, Y. ; Qian, Z. ; Jiang, D. ; Sun, Y. ; Gao, S. ; Jiang, X. ; Wang, H. ; Tao, J.
Neuromedin B receptor stimulation of Cav3.2 T-type Ca2+ channels in primary sensory neurons mediates peripheral pain hypersensitivity.Jiang, D. ; Rinkevich, Y.
Furnishing wound repair by the subcutaneous fascia.Hu, Y. ; Ciminieri, C. ; Hu, Q. ; Lehmann, M. ; Königshoff, M. ; Gosens, R.
WNT signalling in lung physiology and pathology.Förster, K. ; Roth, C.J. ; Hilgendorff, A. ; Ertl-Wagner, B. ; Flemmer, A.W. ; Wall, W.A.
In silico numerical simulation of ventilator settings during high-frequency ventilation in preterm infants.Jacobsen, H. ; Walendy-Gnirß, K. ; Tekin-Bubenheim, N. ; Kouassi, N.M. ; Ben-Batalla, I. ; Berenbrok, N. ; Wolff, M. ; dos Reis, V.P. ; Zickler, M. ; Scholl, L. ; Gries, A. ; Jania, H. ; Kloetgen, A. ; Düsedau, A. ; Pilnitz-Stolze, G. ; Jeridi, A. ; Yildirim, A.Ö. ; Fuchs, H. ; Gailus-Durner, V. ; Stoeger, C. ; Hrabě de Angelis, M. ; Manuylova, T. ; Klingel, K. ; Culley, F.J. ; Behrends, J. ; Loges, S. ; Schneider, B. ; Krauss-Etschmann, S. ; Openshaw, P.J.M. ; Gabriel, G.
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life.Spiro, J. ; Ceelen, F. ; Kneidinger, N. ; Sommer, W.H. ; Schinner, R. ; Dinkel, J. ; Hesse, N.
Structured reporting of computed tomography examinations in post-lung transplantation patients.Mümmler, C. ; Dünzelmann, K. ; Kneidinger, N. ; Barnikel, M. ; Munker, D. ; Gröger, M. ; Canis, M. ; Behr, J. ; Koch, A. ; Haubner, F. ; Milger, K.
Real-life effectiveness of biological therapies on symptoms in severe asthma with comorbid CRSwNP.Stathopoulos, G.T.
Deciphering SARS-CoV-2 mortality: H1N1 as an aid.Conlon, T.M. ; Knolle, P.A. ; Yildirim, A.Ö.
Local tissue development of type 1 innate lymphoid cells: Guided by interferon-gamma.Cosnier, F. ; Seidel, C. ; Valentino, S. ; Schmid, O. ; Bau, S. ; Vogel, U. ; Devoy, J. ; Gaté, L.
Retained particle surface area dose drives inflammation in rat lungs following acute, subacute, and subchronic inhalation of nanomaterials.Fischer, D.S. ; Ansari, M. ; Wagner, K.I. ; Jarosch, S. ; Huang, Y. ; Mayr, C. ; Strunz, M. ; Lang, N.J. ; D'Ippolito, E. ; Hammel, M. ; Mateyka, L. ; Weber, S. ; Wolff, L.S. ; Witter, K. ; Fernandez, I.E. ; Leuschner, G. ; Milger, K. ; Frankenberger, M. ; Nowak, L. ; Heinig-Menhard, K. ; Koch, I. ; Stoleriu, M.-G. ; Hilgendorff, A. ; Behr, J. ; Pichlmair, A. ; Schubert, B. ; Theis, F.J. ; Busch, D.H. ; Schiller, H. B. ; Schober, K.
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'.Munker, D. ; Veit, T. ; Barton, J. ; Mertsch, P. ; Mümmler, C. ; Osterman, A. ; Khatamzas, E. ; Barnikel, M. ; Hellmuth, J.C. ; Münchhoff, M. ; Walter, J. ; Ghiani, A. ; Munker, S. ; Dinkel, J. ; Behr, J. ; Kneidinger, N. ; Milger, K.
Pulmonary function impairment of asymptomatic and persistently symptomatic patients 4 months after COVID-19 according to disease severity.Laveneziana, P. ; Straus, C. ; Meiners, S.
How and to what extent immunological responses to SARS-CoV-2 shape pulmonary function in COVID-19 patients.Stoleriu, M.-G. ; Gerckens, M. ; Stroh, K. ; Kovács, J. ; Samm, N. ; Obereisenbuchner, F. ; Hetrodt, J. ; Schmidt, F.M. ; Reinmuth, N. ; Heiß-Neumann, M. ; Stacher-Priehse, E. ; Koch, I. ; Behr, J. ; Ketscher, C. ; Grützner, U. ; Hatz, R.
Prevention of COVID-19 in thoracic surgery patients: Lessons learned during the first pandemic wave.van der Vorst, E.P.C. ; Pepe, M. ; Peters, L.J.F. ; Haberbosch, M. ; Jansen, Y. ; Nauman, R. ; Stathopoulos, G.T. ; Weber, C. ; Bidzhekov, K.
Transcriptome signature of miRNA-26b KO mouse model suggests novel targets.Schoeps, B. ; Eckfeld, C. ; Prokopchuk, O. ; Böttcher, J. ; Häußler, D. ; Steiger, K. ; Demir, I.E. ; Knolle, P. ; Soehnlein, O. ; Jenne, D. ; Hermann, C.D. ; Krüger, A.
Timp1 triggers neutrophil extracellular trap formation in pancreatic cancer.Ahookhosh, K. ; Saidi, M. ; Mohammadpourfard, M. ; Aminfar, H. ; Hamishehkar, H. ; Farnoud, A. ; Schmid, O.
Flow structure and particle deposition analyses for optimization of a pressurized metered dose inhaler (pMDI) in a model of tracheobronchial airway.Ballester, B. ; Milara, J. ; Montero, P. ; Cortijo, J.
Muc16 is overexpressed in idiopathic pulmonary fibrosis and induces fibrotic responses mediated by transforming growth factor-β1 canonical pathway.Lu, K. ; Lai, K.P. ; Stöger, T. ; Ji, S. ; Lin, Z. ; Lin, X. ; Chan, T.F. ; Fang, J.K. ; Lo, M. ; Gao, L. ; Qiu, C. ; Chen, S. ; Chen, G. ; Li, L. ; Wang, L.
Detrimental effects of microplastic exposure on normal and asthmatic pulmonary physiology.Behr, J. ; Nathan, S.D.
Pulmonary hypertension in interstitial lung disease: Screening, diagnosis and treatment.Trueblood, M.B. ; Schmid, O. ; Altese, N. ; Hurst, C.J. ; Liu, W. ; Gelles, T. ; Achterberg, S.C. ; Whitefield, P.D. ; Hagen, D.E.
Calibration of gas flow meters using choked flow and an evacuated vessel.Sucre, J. ; Haist, L. ; Bolton, C.E. ; Hilgendorff, A.
Early changes and indicators characterizing lung aging in neonatal chronic lung disease.Nathan, S.D. ; Cottin, V. ; Behr, J. ; Hoeper, M.M. ; Martinez, F.J. ; Corte, T.J. ; Keogh, A.M. ; Leuchte, H. ; Mogulkoc, N. ; Ulrich, S. ; Wuyts, W.A. ; Yao, Z. ; Ley-Zaporozhan, J. ; Mueller-Lisse, U.G. ; Scholle, F. ; Brueggenwerth, G. ; Busse, D. ; Nikkho, S. ; Wells, A.U.
Impact of lung morphology on clinical outcomes with riociguat in patients with pulmonary hypertension and idiopathic interstitial pneumonia: A post hoc subgroup analysis of the RISE-IIP study.Colarusso, C. ; Terlizzi, M. ; Lamort, A.-S. ; Cerqua, I. ; Roviezzo, F. ; Stathopoulos, G.T. ; Pinto, A. ; Sorrentino, R.
Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma.Costa, R. ; Wagner, D.E. ; Doryab, A. ; De Santis, M.M. ; Schorpp, K.K. ; Rothenaigner, I. ; Lehmann, M. ; Baarsma, H.A. ; Liu, X. ; Schmid, O. ; Campillos, M.J. ; Yildirim, A.Ö. ; Hadian, K. ; Königshoff, M.
A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation.Onursal, C. ; Dick, E. ; Angelidis, I. ; Schiller, H. B. ; Staab-Weijnitz, C.A.
Collagen biosynthesis, processing, and maturation in lung ageing.Correa-Gallegos, D. ; Jiang, D. ; Rinkevich, Y.
Fibroblasts as confederates of the immune system.Lehmann, M. ; Königshoff, M.
Regenerative medicine and the hope for a cure.Burgstaller, G. ; Gerckens, M. ; Eickelberg, O. ; Königshoff, M.
Decellularized human lung scaffolds as complex three-dimensional tissue culture models to study functional behavior of fibroblasts.Esteve-Codina, A. ; Hofer, T.P. ; Burggraf, D. ; Heiss-Neumann, M.S. ; Gesierich, W. ; Boland, A. ; Olaso, R. ; Bihoreau, M.T. ; Deleuze, J.F. ; Möller, W. ; Schmid, O. ; Soler Artigas, M. ; Renner, K. ; Hohlfeld, J.M. ; Welte, T. ; Fuehner, T. ; Jerrentrup, L. ; Koczulla, A.R. ; Greulich, T. ; Prasse, A. ; Müller-Quernheim, J. ; Gupta, S. ; Brightling, C. ; Subramanian, D.R. ; Parr, D.G. ; Kolsum, U. ; Gupta, V. ; Barta, I. ; Döme, B. ; Strausz, J. ; Stendardo, M. ; Piattella, M. ; Boschetto, P. ; Korzybski, D. ; Gorecka, D. ; Nowinski, A. ; Dabad, M. ; Fernández-Callejo, M. ; Endesfelder, D. ; zu Castell, W. ; Hiemstra, P.S. ; Venge, P. ; Nößner, E. ; Griebel, T. ; Heath, S. ; Singh, D. ; Gut, I. ; Ziegler-Heitbrock, L.
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes.Jiang, D. ; Rinkevich, Y.
Distinct fibroblasts in scars and regeneration.Yazgili, A.S. ; Meul, T. ; Welk, V. ; Semren, N. ; Kammerl, I.E. ; Meiners, S.
In-gel proteasome assay to determine the activity, amount, and composition of proteasome complexes from mammalian cells or tissues.Mackowiak, C. ; Marchiol, T. ; Paljetak, H.C. ; Fauconnier, L. ; Palomo, J. ; Secher, T. ; Panek, C. ; Sedda, D. ; Savigny, F. ; Erard, F. ; Bragonzi, A. ; Huaux, F. ; Stöger, T. ; Schiller, H. B. ; Sirard, J.C. ; Le Bert, M. ; Couillin, I. ; Quesniaux, V.F.J. ; Togbe, D. ; Ryffel, B.
Chronic Pseudomonas aeruginosa lung infection is IL-1R independent, but relies on MyD88 signaling.Stoleriu, M.-G. ; Gerckens, M. ; Obereisenbuchner, F. ; Zaimova, I. ; Hetrodt, J. ; Mavi, S.C. ; Schmidt, F. ; Schoenlebe, A.A. ; Heinig-Menhard, K. ; Koch, I. ; Jörres, R.A. ; Spiro, J. ; Nowak, L. ; Hatz, R. ; Behr, J. ; Gesierich, W. ; Heiß-Neumann, M. ; Dinkel, J.
Automated quantitative thin slice volumetric low dose CT analysis predicts disease severity in COVID-19 patients.Lutter, J. ; Jörres, R.A. ; Trudzinski, F.C. ; Alter, P. ; Kellerer, C. ; Watz, H. ; Welte, T. ; Bals, R. ; Kauffmann-Guerrero, D. ; Behr, J. ; Holle, R. ; F Vogelmeier, C. ; Kahnert, K.
Treatment of COPD Groups GOLD A and B with inhaled corticosteroids in the COSYCONET cohort - determinants and consequences.Böttcher, A. ; Büttner, M. ; Tritschler, S. ; Sterr, M. ; Aliluev, A. ; Oppenländer, L. ; Burtscher, I. ; Sass, S. ; Irmler, M. ; Beckers, J. ; Ziegenhain, C. ; Enard, W. ; Schamberger, A.C. ; Verhamme, F.M. ; Eickelberg, O. ; Theis, F.J. ; Lickert, H.
Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.Eberherr, A.C. ; Maaske, A. ; Wolf, C. ; Giesert, F. ; Berutti, R. ; Rusha, E. ; Pertek, A. ; Kastlmeier, M.T. ; Voss, C. ; Plummer, M. ; Sayed, A. ; Graf, E. ; Effner, R. ; Volz, T. ; Drukker, M. ; Strom, T.M. ; Meitinger, T. ; Stöger, T. ; Buyx, A.M. ; Hagl, B. ; Renner, E.D.
Rescue of STAT3 function in hyper-IgE syndrome using adenine base editing.Phalen, R.F. ; Hoover, M.D. ; Oldham, M.J. ; Schmid, O. ; Golshahi, L.
Anatomical considerations for inhaled aerosol deposition modeling: Methods, applications, challenges and opportunities.Macrini, C. ; Gerhards, R. ; Winklmeier, S. ; Bergmann, L. ; Mader, S. ; Spadaro, M. ; Vural, A. ; Smolle, M. ; Hohlfeld, R. ; Kümpfel, T. ; Lichtenthaler, S.F. ; Franquelim, H.G. ; Jenne, D. ; Meinl, E.
Features of MOG required for recognition by patients with MOG antibody-associated disorders.Stauffer, E. ; Weber, P. ; Heider, T. ; Dalke, C. ; Blutke, A. ; Walch, A.K. ; Burgstaller, G. ; Brix, N. ; Lauber, K. ; Zitzelsberger, H. ; Unger, K. ; Selmansberger, M.
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.Fernandez, I.E. ; Kass, D.J.
Do circulating monocytes promote and predict IPF progression?Hynds, R.E. ; Zacharias, W.J. ; Nikolić, M.Z. ; Königshoff, M. ; Eickelberg, O. ; Gosens, R. ; de Coppi, P. ; Janes, S.M. ; Morrisey, E. ; Clevers, H. ; Ryan, A.L. ; Stripp, B.R. ; Sun, X. ; Kim, C.F. ; Lin, Q.S.
National heart, lung and blood institute and building respiratory epithelium and tissue for health (BREATH) consortium workshop report: Moving forward in lung regeneration.Mayr, C. ; Simon, L. ; Leuschner, G. ; Ansari, M. ; Schniering, J. ; Geyer, P.E. ; Angelidis, I. ; Strunz, M. ; Singh, P. ; Kneidinger, N. ; Reichenberger, F. ; Silbernagel, E. ; Böhm, S. ; Adler, H. ; Lindner, M. ; Maurer, B. ; Hilgendorff, A. ; Prasse, A. ; Behr, J. ; Mann, M. ; Eickelberg, O. ; Theis, F.J. ; Schiller, H. B.
Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers.Conlon, T.M. ; John-Schuster, G. ; Heide, D. ; Pfister, D. ; Lehmann, M. ; Hu, Y. ; Ertüz, Z. ; López, M.A. ; Ansari, M. ; Strunz, M. ; Mayr, C. ; Angelidis, I. ; Ciminieri, C. ; Costa, R. ; Kohlhepp, M.S. ; Guillot, A. ; Güneş, G. ; Jeridi, A. ; Funk, M.C. ; Beroshvili, G. ; Prokosch, S. ; Hetzer, J. ; Verleden, S.E. ; Alsafadi, H.N. ; Lindner, M. ; Burgstaller, G. ; Becker, L. ; Irmler, M. ; Dudek, M. ; Janzen, J. ; Goffin, E. ; Gosens, R. ; Knolle, P. ; Pirotte, B. ; Stöger, T. ; Beckers, J. ; Wagner, D.E. ; Singh, I. ; Theis, F.J. ; Hrabě de Angelis, M. ; O’Connor, T. ; Tacke, F. ; Boutros, M. ; Dejardin, E. ; Eickelberg, O. ; Schiller, H. B. ; Königshoff, M. ; Heikenwalder, M. ; Yildirim, A.Ö.
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung (Nature, (2020), 588, 7836, (151-156), 10.1038/s41586-020-2882-8).Spella, M. ; Lilis, I. ; Stathopoulos, G.T.
A method for the establishment and characterization of mouse lung adenocarcinoma cell lines that mimic traits of human adenocarcinomas.Doryab, A. ; Taskin, M.B. ; Stahlhut, P. ; Schröppel, A. ; Orak, S. ; Voss, C. ; Ahluwalia, A. ; Rehberg, M. ; Hilgendorff, A. ; Stöger, T. ; Groll, J. ; Schmid, O.
A bioinspired in vitro lung model to study particokinetics of nano-/microparticles under cyclic stretch and air-liquid interface conditions.Wenter, V. ; Albert, N.L. ; Ahmaddy, F. ; Unterrainer, M. ; Hornung, J. ; Ilhan, H. ; Bartenstein, P. ; Spitzweg, C. ; Kneidinger, N. ; Todica, A.
The diagnostic challenge of coexistent sarcoidosis and thyroid cancer - a retrospective study.Weiss, S.A. ; Rehm, S.R.T. ; Perera, N.C. ; Biniossek, M.L. ; Schilling, O. ; Jenne, D.
Origin and expansion of the serine protease repertoire in the myelomonocyte lineage.Wan, L. ; Jiang, D. ; Correa-Gallegos, D. ; Ramesh, P. ; Zhao, J. ; Ye, H. ; Zhu, S. ; Wannemacher, J. ; Volz, T. ; Rinkevich, Y.
Connexin43 gap junction drives fascia mobilization and repair of deep skin wounds.Huang, Y. ; Ye, H. ; Zhu, F. ; Hu, C. ; Zheng, Y.
The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice.Spella, M. ; Stathopoulos, G.T.
Immune resistance in lung adenocarcinoma.Kannavou, M. ; Marazioti, A. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Engineered versus hybrid cellular vesicles as efficient drug delivery systems: A comparative study with brain targeted vesicles.Brunn, D. ; Turkowski, K. ; Günther, S. ; Weigert, A. ; Muley, T. ; Kriegsmann, M. ; Winter, H. ; Dammann, R.H. ; Stathopoulos, G.T. ; Thomas, M. ; Guenther, A. ; Grimminger, F. ; Pullamsetti, S.S. ; Seeger, W. ; Savai, R.
Interferon regulatory factor 9 promotes lung cancer progression via regulation of versican.Muus, C. ; Luecken, M. ; Eraslan, G. ; Sikkema, L. ; Waghray, A. ; Heimberg, G. ; Kobayashi, Y. ; Vaishnav, E.D. ; Subramanian, A. ; Smillie, C. ; Jagadeesh, K.A. ; Duong, E.T. ; Fiskin, E. ; Triglia, E.T. ; Ansari, M. ; Cai, P. ; Lin, B. ; Buchanan, J. ; Chen, S. ; Shu, J. ; Haber, A.L. ; Chung, H. ; Montoro, D.T. ; Adams, T. ; Aliee, H. ; Allon, S.J. ; Andrusivova, Z. ; Angelidis, I. ; Ashenberg, O. ; Bassler, K. ; Bécavin, C. ; Benhar, I. ; Bergenstråhle, J. ; Bergenstråhle, L. ; Bolt, L. ; Braun, E. ; Bui, L.T. ; Callori, S. ; Chaffin, M. ; Chichelnitskiy, E. ; Chiou, J. ; Conlon, T.M. ; Cuoco, M.S. ; Cuomo, A.S.E. ; Deprez, M. ; Duclos, G. ; Fine, D. ; Fischer, D.S. ; Ghazanfar, S. ; Gillich, A. ; Giotti, B. ; Gould, J. ; Guo, M. ; Gutierrez, A.J. ; Habermann, A.C. ; Harvey, T. ; He, P. ; Hou, X. ; Hu, L. ; Hu, Y. ; Jaiswal, A. ; Ji, L. ; Jiang, P. ; Kapellos, T.S. ; Kuo, C.S. ; Larsson, L. ; Leney-Greene, M.A. ; Lim, K. ; Litviňuková, M. ; Ludwig, L.S. ; Lukassen, S. ; Luo, W. ; Maatz, H. ; Madissoon, E. ; Mamanova, L. ; Manakongtreecheep, K. ; Leroy, S. ; Mayr, C. ; Mbano, I.M. ; McAdams, A.M. ; Nabhan, A.N. ; Nyquist, S.K. ; Penland, L. ; Poirion, O.B. ; Poli, S. ; Qi, C. ; Queen, R. ; Reichart, D. ; Rosas, I. ; Schupp, J.C. ; Shea, C.V. ; Shi, X. ; Sinha, R. ; Sit, R.V. ; Slowikowski, K. ; Slyper, M. ; Smith, N.P. ; Sountoulidis, A. ; Strunz, M. ; Sullivan, T.B. ; Sun, D. ; Talavera-López, C. ; Tan, P. ; Tantivit, J. ; Travaglini, K.J. ; Tucker, N.R. ; Vernon, K.A. ; Wadsworth, M.H. ; Waldman, J. ; Wang, X. ; Xu, K. ; Yan, W. ; Zhao, W. ; Ziegler, C.G.K.
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.Böttcher, A. ; Büttner, M. ; Tritschler, S. ; Sterr, M. ; Aliluev, A. ; Oppenländer, L. ; Burtscher, I. ; Sass, S. ; Irmler, M. ; Beckers, J. ; Ziegenhain, C. ; Enard, W. ; Schamberger, A.C. ; Verhamme, F.M. ; Eickelberg, O. ; Theis, F.J. ; Lickert, H.
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.Wjst, M.
Scientific integrity is threatened by image duplications.Petrera, A. ; von Toerne, C. ; Behler, J. ; Huth, C. ; Thorand, B. ; Hilgendorff, A. ; Hauck, S.M.
Multiplatform approach for plasma proteomics: Complementarity of olink proximity extension assay technology to mass spectrometry-based protein profiling.von Schirnding, C. ; Giopanou, I. ; Hermawan, A. ; Wehl, L. ; Ntaliarda, G. ; Illes, R. ; Datz, S. ; Geisslinger, F. ; Bartel, K. ; Sommer, A.-K. ; Lianou, M. ; Weiß, V. ; Feckl, J. ; Vollmar, A.M. ; Bräuchle, C. ; Stathopoulos, G.T. ; Wagner, E. ; Roidl, A. ; Bein, T. ; Engelke, H.
Synergistic combination of calcium and citrate in mesoporous nanoparticles targets pleural tumors.De Santis, M. ; Alsafadi, H.N. ; Tas, S. ; Bölükbas, D.A. ; Prithiviraj, S. ; Da Silva, I.A.N. ; Mittendorfer, M. ; Ota, C. ; Stegmayr, J. ; Daoud, F. ; Königshoff, M. ; Swärd, K. ; Wood, J.A. ; Tassieri, M. ; Bourgine, P.E. ; Lindstedt, S. ; Mohlin, S. ; Wagner, D.E.
Extracellular-matrix-reinforced bioinks for 3D bioprinting human tissue.Cei, D. ; Doryab, A. ; Lenz, A.-G. ; Schröppel, A. ; Mayer, P. ; Burgstaller, G. ; Nossa, R. ; Ahluwalia, A. ; Schmid, O.
Development of a dynamic in vitro stretch model of the alveolar interface with aerosol delivery.Behr, J. ; Nathan, S.D. ; Wuyts, W.A. ; Mogulkoc Bishop, N. ; Bouros, D.E. ; Antoniou, K. ; Guiot, J. ; Kramer, M.R. ; Kirchgaessler, K.U. ; Bengus, M. ; Gilberg, F. ; Perjesi, A. ; Harari, S. ; Wells, A.U.
Efficacy and safety of sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A double-blind, randomised, placebo-controlled, phase 2b trial.Lodge, C.J. ; Lowe, A.J. ; Milanzi, E. ; Bowatte, G. ; Abramson, M.J. ; Tsimiklis, H. ; Axelrad, C. ; Robertson, B. ; Darling, A.E. ; Svanes, C. ; Wjst, M. ; Dharmage, S.C. ; Bode, L.
Human milk oligosaccharide profiles and allergic disease up to 18 years.Wjst, M.
Erratum: Die frühe Phase der COVID-19-Pandemie in Bayern.Kaiser, J.C. ; Stathopoulos, G.T.
Socioeconomic correlates of SARS-CoV-2 and influenza H1N1 outbreaks.Ubags, N.D. ; Baker, J. ; Boots, A. ; Costa, R. ; El-Merhie, N. ; Fabre, A. ; Faiz, A. ; Heijink, I.H. ; Hiemstra, P.S. ; Lehmann, M. ; Meiners, S. ; Rolandsson Enes, S. ; Bartel, S.
ERS International Congress, Madrid, 2019: Highlights from the basic and translational science assembly.Bölükbas, D.A. ; Datz, S. ; Meyer-Schwickerath, C. ; Morrone, C. ; Doryab, A. ; Gößl, D. ; Vreka, M. ; Yang, L. ; Argyo, C. ; van Rijt, S.H. ; Lindner, M. ; Eickelberg, O. ; Stöger, T. ; Schmid, O. ; Lindstedt, S. ; Stathopoulos, G.T. ; Bein, T. ; Wagner, D.E. ; Meiners, S.
Organ‐restricted vascular delivery of nanoparticles for lung cancer therapy.Doryab, A. ; Taskin, M.B. ; Stahlhut, P. ; Schröppel, A. ; Wagner, D.E. ; Groll, J. ; Schmid, O.
A biomimetic, copolymeric membrane for cell-stretch experiments with pulmonary epithelial cells at the air-liquid interface.Leuschner, G. ; Klotsche, J. ; Kreuter, M. ; Prasse, A. ; Wirtz, H. ; Pittrow, D. ; Frankenberger, M. ; Behr, J. ; Kneidinger, N.
Idiopathic pulmonary fibrosis in elderly patients: Analysis of the INSIGHTS-IPF Observational Study.Morrone, C. ; Smirnova, N.F. ; Jeridi, A. ; Kneidinger, N. ; Hollauer, C. ; Schupp, J.C. ; Kaminski, N. ; Jenne, D. ; Eickelberg, O. ; Yildirim, A.Ö.
Cathepsin B promotes collagen biosynthesis driving Bronchiolitis Obliterans Syndrome.Stoleriu, M.-G. ; Gerckens, M. ; Hetrodt, J. ; Heiß-Neumann, M. ; Koch, I. ; Stacher-Priehse, E. ; Dinkel, J. ; Behr, J. ; Grützner, U. ; Hatz, R.
Clinical course of three postoperative symptomatic COVID-19 cases in patients after lung lobectomy.Lutter, J. ; Jörres, R.A. ; Welte, T. ; Watz, H. ; Waschki, B. ; Alter, P. ; Trudzinski, F.C. ; Ohlander, J. ; Behr, J. ; Bals, R. ; Studnicka, M. ; Holle, R. ; Vogelmeier, C.F. ; Kahnert, K.
Impact of education on COPD severity and all-cause mortality in lifetime never-smokers and longtime ex-smokers: Results of the COSYCONET cohort.Umkehrer, S. ; Morrone, C. ; Dinkel, J. ; Aigner, L. ; Reiser, M.F. ; Herzen, J. ; Yildirim, A.Ö. ; Pfeiffer, F. ; Hellbach, K.
A proof-of principal study using phase-contrast imaging for the detection of large airway pathologies after lung transplantation.Hoeper, M.M. ; Pausch, C. ; Grünig, E. ; Klose, H. ; Staehler, G. ; Huscher, D. ; Pittrow, D. ; Olsson, K.M. ; Vizza, C.D. ; Gall, H. ; Benjamin, N. ; Distler, O. ; Opitz, C. ; Gibbs, J.S.R. ; Delcroix, M. ; Ghofrani, H.A. ; Rosenkranz, S. ; Ewert, R. ; Kaemmerer, H. ; Lange, T.J. ; Kabitz, H.J. ; Skowasch, D. ; Skride, A. ; Jureviciene, E. ; Paleviciute, E. ; Miliauskas, S. ; Claussen, M. ; Behr, J. ; Milger, K. ; Halank, M. ; Wilkens, H. ; Wirtz, H. ; Pfeuffer-Jovic, E. ; Harbaum, L. ; Scholtz, W. ; Dumitrescu, D. ; Bruch, L. ; Coghlan, G. ; Neurohr, C. ; Tsangaris, I. ; Gorenflo, M. ; Scelsi, L. ; Vonk-Noordegraaf, A. ; Ulrich, S. ; Held, M.
Idiopathic pulmonary arterial hypertension phenotypes determined by cluster analysis from the COMPERA registry.Melo-Narváez, C. ; Stegmayr, J. ; Wagner, D.E. ; Lehmann, M.
Lung regeneration: Implications of the diseased niche and ageing.Veit, T. ; Barnikel, M. ; Crispin, A. ; Kneidinger, N. ; Ceelen, F. ; Arnold, P. ; Munker, D. ; Schmitzer, M. ; Barton, J. ; Schiopu, S. ; Schiller, H. B. ; Frankenberger, M. ; Milger, K. ; Behr, J. ; Neurohr, C. ; Leuschner, G.
Variability of forced vital capacity in progressive interstitial lung disease: A prospective observational study.Jiang, D. ; Christ, S. ; Correa-Gallegos, D. ; Ramesh, P. ; Kalgudde Gopal, S. ; Wannemacher, J. ; Mayr, C. ; Lupperger, V. ; Yu, Q. ; Ye, H. ; Mück-Häusl, M. ; Rajendran, V. ; Wan, L. ; Liu, J. ; Mirastschijski, U. ; Volz, T. ; Marr, C. ; Schiller, H. B. ; Rinkevich, Y.
Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin.Conlon, T.M. ; John-Schuster, G. ; Heide, D. ; Pfister, D. ; Lehmann, M. ; Hu, Y. ; Ertüz, Z. ; López, M.A. ; Ansari, M. ; Strunz, M. ; Mayr, C. ; Ciminieri, C. ; Costa, R. ; Kohlhepp, M.S. ; Guillot, A. ; Güneş, G. ; Jeridi, A. ; Funk, M.C. ; Beroshvili, G. ; Prokosch, S. ; Hetzer, J. ; Verleden, S.E. ; Alsafadi, H.N. ; Lindner, M. ; Burgstaller, G. ; Becker, L. ; Irmler, M. ; Dudek, M. ; Janzen, J. ; Goffin, E. ; Gosens, R. ; Knolle, P. ; Pirotte, B. ; Stöger, T. ; Beckers, J. ; Wagner, D.E. ; Singh, I. ; Theis, F.J. ; Hrabě de Angelis, M. ; O’Connor, T. ; Tacke, F. ; Boutros, M. ; Dejardin, E. ; Eickelberg, O. ; Schiller, H. B. ; Königshoff, M. ; Heikenwalder, M. ; Yildirim, A.Ö.
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.Kirsch, F. ; Schramm, A. ; Kurz, C.F. ; Schwarzkopf, L. ; Lutter, J. ; Huber, M.B. ; Leidl, R.
Effect of BMI on health care expenditures stratified by COPD GOLD severity grades: Results from the LQ-DMP study.Kanellakis, N.I. ; Asciak, R. ; Hamid, M.A. ; Yao, X. ; McCole, M. ; McGowan, S. ; Seraia, E. ; Hatch, S. ; Hallifax, R.J. ; Mercer, R.M. ; Bedawi, E.O. ; Jones, S. ; Verrill, C. ; Dobson, M. ; George, V. ; Stathopoulos, G.T. ; Peng, Y. ; Ebner, D. ; Dong, T. ; Rahman, N.M. ; Psallidas, I.
Patient-derived malignant pleural mesothelioma cell cultures: A tool to advance biomarker-driven treatments.Farnoud, A. ; Tofighian, H. ; Baumann, I. ; Garcia, G.J.M. ; Schmid, O. ; Gutheil, E. ; Rashidi, M.M.
Large eddy simulations of airflow and particle deposition in pulsating bi-directional nasal drug delivery.Erben, A. ; Hörning, M. ; Hartmann, B. ; Becke, T. ; Eisler, S.A. ; Southan, A. ; Cranz, S. ; Hayden, O. ; Kneidinger, N. ; Königshoff, M. ; Lindner, M. ; Tovar, G.E.M. ; Burgstaller, G. ; Clausen-Schaumann, H. ; Sudhop, S. ; Heymann, M.
Precision 3D-printed cell scaffolds mimicking native tissue composition and mechanics.Weber, J. ; Rajan, S. ; Schremmer, C. ; Chao, Y.K. ; Krasteva-Christ, G. ; Kannler, M. ; Yildirim, A.Ö. ; Brosien, M. ; Schredelseker, J. ; Weissmann, N. ; Grimm, C. ; Gudermann, T. ; Dietrich, A.
TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema.Maqhuzu, P.N. ; Szentes, B.L. ; Kreuter, M. ; Bahmer, T. ; Kahn, N. ; Claussen, M. ; Holle, R. ; Schwarzkopf, L.
Determinants of health-related quality of life decline in interstitial lung disease.Kokot, H. ; Kokot, B. ; Sebastijanović, A. ; Voss, C. ; Podlipec, R. ; Zawilska, P. ; Berthing, T. ; Ballester-Lopez, C. ; Danielsen, P.H. ; Contini, C. ; Ivanov, M. ; Krišelj, A. ; Čotar, P. ; Zhou, Q. ; Ponti, J. ; Zhernovkov, V. ; Schneemilch, M. ; Doumandji, Z. ; Pušnik, M. ; Umek, P. ; Pajk, S. ; Joubert, O. ; Schmid, O. ; Urbančič, I. ; Irmler, M. ; Beckers, J. ; Lobaskin, V. ; Halappanavar, S. ; Quirke, N. ; Lyubartsev, A.P. ; Vogel, U. ; Koklič, T. ; Stöger, T. ; Štrancar, J.
Prediction of chronic inflammation for inhaled particles: The impact of material cycling and quarantining in the lung epithelium.Ding, Y. ; Weindl, P. ; Lenz, A.-G. ; Mayer, P. ; Krebs, T. ; Schmid, O.
Quartz crystal microbalances (QCM) are suitable for real-time dosimetry in nanotoxicological studies using VITROCELL®Cloud cell exposure systems.Mümmler, C. ; Munker, D. ; Barnikel, M. ; Veit, T. ; Kayser, M. ; Welte, T. ; Behr, J. ; Kneidinger, N. ; Suhling, H. ; Milger, K.
Dupilumab improves asthma control and lung function in patients with insufficient outcome during previous antibody therapy.Behr, J. ; Prasse, A. ; Wirtz, H. ; Koschel, D. ; Pittrow, D. ; Held, M. ; Klotsche, J. ; Andreas, S. ; Claussen, M. ; Grohe, C. ; Wilkens, H. ; Hagmeyer, L. ; Skowasch, D. ; Meyer, J.F. ; Kirschner, J. ; Glaeser, S. ; Kahn, N. ; Welte, T. ; Neurohr, C. ; Schwaiblmair, M. ; Bahmer, T. ; Oqueka, T. ; Frankenberger, M. ; Kreuter, M.
Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: Long-term results of the INSIGHTS-IPF registry.Munkhbaatar, E. ; Dietzen, M. ; Agarwal, D. ; Anton, M. ; Jesinghaus, M. ; Boxberg, M. ; Pfarr, N. ; Bidola, P. ; Uhrig, S. ; Höckendorf, U. ; Meinhardt, A.L. ; Wahida, A. ; Heid, I. ; Braren, R. ; Mishra, R. ; Warth, A. ; Muley, T. ; Poh, P.S.P. ; Wang, X. ; Fröhling, S. ; Steiger, K. ; Slotta-Huspenina, J. ; van Griensven, M. ; Pfeiffer, F. ; Lange, S. ; Rad, R. ; Spella, M. ; Stathopoulos, G.T. ; Ruland, J. ; Bassermann, F. ; Weichert, W. ; Strasser, A. ; Branca, C. ; Heikenwalder, M. ; Swanton, C. ; McGranahan, N. ; Jost, P.J.
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.Käsmann, L. ; Dietrich, A. ; Staab-Weijnitz, C.A. ; Manapov, F. ; Behr, J. ; Rimner, A. ; Jeremic, B. ; Senan, S. ; De Ruysscher, D. ; Lauber, K. ; Belka, C.
Radiation-induced lung toxicity - cellular and molecular mechanisms of pathogenesis, management, and literature review.Gouda, M. ; Rex, D.A.B. ; Priya, S.E.S. ; Modi, P.K. ; Chanderasekaran, J. ; Bhandary, Y.P.
Proteomics analysis revealed the importance of inflammation mediated downstream pathways and the protective role of curcumin during bleomycin-induced pulmonary fibrosis in C57BL/6 mice.Kahnert, K. ; Jörres, R.A. ; Kauczor, H.U. ; Biederer, J. ; Jobst, B. ; Alter, P. ; Biertz, F. ; Mertsch, P. ; Lucke, T. ; Lutter, J. ; Trudzinski, F.C. ; Behr, J. ; Bals, R. ; Watz, H. ; Vogelmeier, C.F. ; Welte, T.
Relationship between clinical and radiological signs of bronchiectasis in COPD patients: Results from COSYCONET.Jiang, D. ; Scharffetter-Kochanek, K.
Mesenchymal stem cells adaptively respond to environmental cues thereby improving granulation tissue formation and wound healing.Korfei, M. ; MacKenzie, B. ; Meiners, S.
The ageing lung under stress.Farnoud, A. ; Baumann, I. ; Rashidi, M.M. ; Schmid, O. ; Gutheil, E.
Simulation of patient-specific bi-directional pulsating nasal aerosol dispersion and deposition with clockwise 45 degrees and 90 degrees nosepieces.Strunz, M. ; Simon, L. ; Ansari, M. ; Kathiriya, J.J. ; Angelidis, I. ; Mayr, C. ; Tsidiridis, G. ; Lange, M. ; Mattner, L. ; Yee, M. ; Ogar, P. ; Sengupta, A. ; Kukhtevich, I. ; Schneider, R. ; Zhao, Z. ; Voss, C. ; Stöger, T. ; Neumann, J.H.L. ; Hilgendorff, A. ; Behr, J. ; O'Reilly, M. ; Lehmann, M. ; Burgstaller, G. ; Königshoff, M. ; Chapman, H.A. ; Theis, F.J. ; Schiller, H. B.
Alveolar regeneration through a Krt8+transitional stem cell state that persists in human lung fibrosis.Arendt, K.A.M.
An in vivo inflammatory loop potentiates KRAS blockade.Meul, T. ; Berschneider, K. ; Schmitt, S. ; Mayr, C. ; Mattner, L. ; Schiller, H. B. ; Yazgili, A.S. ; Wang, X. ; Lukas, C. ; Schlesser, C. ; Prehn, C. ; Adamski, J. ; Graf, E. ; Schwarzmayr, T. ; Perocchi, F. ; Kukat, A. ; Trifunovic, A. ; Kremer, L.S. ; Prokisch, H. ; Popper, B. ; von Toerne, C. ; Hauck, S.M. ; Zischka, H. ; Meiners, S.
Mitochondrial regulation of the 26S proteasome.Jarosch, I. ; Schneeberger, T. ; Gloeckl, R. ; Kreuter, M. ; Frankenberger, M. ; Neurohr, C. ; Prasse, A. ; Freise, J. ; Behr, J. ; Hitzl, W. ; Koczulla, A.R. ; Kenn, K.
Short-term effects of comprehensive pulmonary rehabilitation and its maintenance in patients with idiopathic pulmonary fibrosis: A randomized controlled trial.Sarode, P. ; Zheng, X. ; Giotopoulou, G.A. ; Weigert, A. ; Kuenne, C. ; Günther, S. ; Friedrich, A. ; Gattenlöhner, S. ; Stiewe, T. ; Brüne, B. ; Grimminger, F. ; Stathopoulos, G.T. ; Pullamsetti, S.S. ; Seeger, W. ; Savai, R.
Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer.Nikou, S. ; Arbi, M. ; Dimitrakopoulos, F.D. ; Sirinian, C. ; Chadla, P. ; Pappa, I. ; Ntaliarda, G. ; Stathopoulos, G.T. ; Papadaki, H. ; Zolota, V. ; Lygerou, Z. ; Kalofonos, H.P. ; Bravou, V.
Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival.Fischer, A. ; Koopmans, T. ; Ramesh, P. ; Christ, S. ; Strunz, M. ; Wannemacher, J. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Ansari, M. ; Theis, F.J. ; Schorpp, K.K. ; Hadian, K. ; Neumann, P.A. ; Schiller, H. B. ; Rinkevich, Y.
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.Alsafadi, H.N. ; Uhl, F.E. ; Pineda, R.H. ; Bailey, K.E. ; Rojas, M. ; Wagner, D.E. ; Königshoff, M.
Applications and approaches for three-dimensional precision-cut lung slices disease modeling and drug discovery.Szentes, B.L. ; Schultz, K. ; Nowak, D. ; Schüler, M. ; Schwarzkopf, L.
How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire?Hu, Y. ; Ng-Blichfeldt, J.P. ; Ota, C. ; Ciminieri, C. ; Ren, W. ; Hiemstra, P.S. ; Stolk, J. ; Gosens, R. ; Königshoff, M.
Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema.Kreyling, W.G. ; Holzwarth, U. ; Hirn, S. ; Schleh, C. ; Wenk, A. ; Schäffler, M. ; Haberl, N. ; Gibson, N.
Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm silver nanoparticle aerosols in healthy adult rats after a single 11/2-hour inhalation exposure.Halappanavar, S. ; van den Brule, S. ; Nymark, P. ; Gaté, L. ; Seidel, C. ; Valentino, S. ; Zhernovkov, V. ; Høgh Danielsen, P. ; De Vizcaya, A. ; Wolff, H. ; Stöger, T. ; Boyadziev, A. ; Poulsen, S.S. ; Sørli, J.B. ; Vogel, U.
Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale.Coux, O. ; Zieba, B.A. ; Meiners, S.
The proteasome system in health and disease.Munir, S. ; Basu, A. ; Maity, P. ; Krug, L. ; Haas, P. ; Jiang, D. ; Strauss, G. ; Wlaschek, M. ; Geiger, H. ; Singh, K. ; Scharffetter-Kochanek, K.
TLR4-dependent shaping of the wound site by MSCs accelerates wound healing.Wang, X. ; Meul, T. ; Meiners, S.
Exploring the proteasome system: A novel concept of proteasome inhibition and regulation.Bondesson, D. ; Silbernagel, E. ; Behr, J. ; Reichenberger, F. ; Dinkel, J.
Automated evaluation of probe-based confocal laser endomicroscopy in the lung.Hu, C. ; Meiners, S. ; Lukas, C. ; Stathopoulos, G.T. ; Chen, J.
Role of exosomal microRNAs in lung cancer biology and clinical applications.Alhasan, M.M. ; Cait, A.M. ; Heimesaat, M.M. ; Blaut, M. ; Klopfleisch, R. ; Wedel, A. ; Conlon, T.M. ; Yildirim, A.Ö. ; Sodemann, E.B. ; Mohn, W.W. ; Bereswill, S. ; Conrad, M.L.
Antibiotic use during pregnancy increases offspring asthma severity in a dose-dependent manner.Lasch, F. ; Karch, A. ; Koch, A. ; Derlin, T. ; Voskrebenzev, A. ; Alsady, T.M. ; Hoeper, M.M. ; Gall, H. ; Roller, F. ; Harth, S. ; Steiner, D. ; Krombach, G. ; Ghofrani, H.A. ; Rengier, F. ; Heußel, C.P. ; Grünig, E. ; Beitzke, D. ; Hacker, M. ; Lang, I.M. ; Behr, J. ; Bartenstein, P. ; Dinkel, J. ; Schmidt, K.H. ; Kreitner, K.F. ; Frauenfelder, T. ; Ulrich, S. ; Hamer, O.W. ; Pfeifer, M. ; Johns, C.S. ; Kiely, D.G. ; Swift, A.J. ; Wild, J. ; Vogel-Claussen, J.
Comparison of MRI and VQ-SPECT as a screening test for patients with suspected CTEPH: CHANGE-MRI study design and rationale.Grosch, M. ; Rusha, E. ; Ori, C. ; Truong, D.J.J. ; O'Neill, A.C. ; Pertek, A. ; Westmeyer, G.G. ; Drukker, M.
Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation.Liu, H. ; Zistler, K. ; Jeridi, A. ; Morrone, C. ; Schulte-Doeinghaus, S. ; Hagl, C. ; Yildirim, A.Ö. ; Michel, S. ; Dashkevich, A.
Rapid activation of pro-lymphangiogenic phenotype and consequent increase of lymphatic density occurs during the development of chronic lung allograft dysfunction.Morrone, C. ; Rehm, S.R.T. ; Smirnova, N. ; Doryab, A. ; Schmid, O. ; Eickelberg, O. ; Yildirim, A.Ö. ; Jenne, D.
Regulation of cysteine-protease activity prevents graft dysfunction during ischemia-lung reperfusion.Jiang, D. ; Ramesh, P. ; Christ, S. ; Correa-Gallegos, D. ; Gopal, S.K. ; Yu, Q. ; Lupperger, V. ; Marr, C. ; Rinkevich, Y.
Scar formation is driven by N-cadherin dependent collective fibroblast migration.Correa-Gallegos, D. ; Jiang, D. ; Rinkevich, Y.
Subcutaneous fascia is a cell repository for scars.Christ, S. ; Jiang, D. ; Correa-Gallegos, D. ; Ramesh, P. ; Rinkevich, Y.
Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring.Kastlmeier, M.T. ; Stöger, T. ; Hilgendorff, A. ; Voss, C.
HIPSC in vitro model for therapeutic strategies in fibrotic regeneration.Vladar, E.K. ; Königshoff, M.
Noncanonical Wnt planar cell polarity signaling in lung development and disease.Lehmann, M. ; Hu, Q. ; Hu, Y. ; Hafner, K. ; Costa, R. ; van den Berg, A. ; Königshoff, M.
Chronic WNT/β-catenin signaling induces cellular senescence in lung epithelial cells.Cranz, S. ; Gerckens, M. ; Sengupta, A. ; Sahabian, A. ; Ori, C. ; Martin, U. ; Drukker, M. ; Lindner, M. ; Behr, J. ; Olmer, R. ; Königshoff, M. ; Burgstaller, G.
Rebuilding new lungs: Studying homing of progenitor lung cell types into their native niche of decellularized ex vivo human lung slices by 4D live-cell light-sheet microscopy.Jiang, D. ; de Vries, J. ; Muschhammer, J. ; Schatz, S. ; Hein, T. ; Fidan, M. ; Romanov, V. ; Rinkevich, Y. ; Scharffetter-Kochanek, K.
Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing.Conlon, T.M. ; Sarker, R.S. ; Morrone, C. ; Srivastava, B. ; Fehrenbach, H. ; Yildirim, A.Ö.
Regeneration of airway epithelial cell regulated by arginine methylation.Strunz, M. ; Simon, L. ; Ansari, M. ; Mattner, L. ; Angelidis, I. ; Mayr, C. ; Kathiriya, J. ; Yee, M. ; Ogar, P. ; Voss, C. ; Stöger, T. ; Kukhtevich, I. ; Schneider, R. ; Lehmann, M. ; Koenigshoff, M. ; Burgstaller, G. ; O'Reilly, M. ; Chapman, H. ; Theis, F.J. ; Schiller, H. B.
Fate trajectory modeling reveals convergence of airway derived progenitors and AT2 cells on transient KRT8+alveolar cell state during lung regeneration.Sodemann, E.B. ; Dähling, S. ; Klopfleisch, R. ; Boiarina, E. ; Cataldo, D. ; Alhasan, M.M. ; Yildirim, A.Ö. ; Witzenrath, M. ; Tabeling, C. ; Conrad, M.L.
Maternal asthma is associated with persistent changes in allergic offspring antibody glycosylation.Ehrmann, S. ; Schmid, O. ; Darquenne, C. ; Rothen-Rutishauser, B. ; Sznitman, J. ; Yang, L. ; Barosova, H. ; Vecellio, L. ; Mitchell, J. ; Henze-Vourc´h, N.
Innovative preclinical models for pulmonary drug delivery research.Hadrup, N. ; Zhernovkov, V. ; Jacobsen, N.R. ; Voss, C. ; Strunz, M. ; Schiller, H. B. ; Halappanavar, S. ; Poulsen, S.S. ; Kholodenko, B. ; Stöger, T. ; Saber, A.T. ; Vogel, U.
Acute phase response as a biological mechanism-of-action of (nano)particle-induced cardiovascular disease.Kollmus, H. ; Fuchs, H. ; Lengger, C. ; Haselimashhadi, H. ; Bogue, M.A. ; Östereicher, M.A. ; Horsch, M. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Beckers, J. ; Calzada-Wack, J. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Klein-Rodewald, T. ; Maier, H. ; Mayer-Kuckuk, P. ; Miller, G. ; Moreth, K. ; Neff, F. ; Rathkolb, B. ; Rácz, I. ; Rozman, J. ; Spielmann, N. ; Treise, I. ; Busch, D.H. ; Graw, J. ; Klopstock, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Mason, J. ; Torres, A. ; Balling, R. ; Mehaan, T. ; Gailus-Durner, V. ; Schughart, K. ; Hrabě de Angelis, M.
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.Jiang, D. ; Rinkevich, Y.
Scars or regeneration?-Dermal fibroblasts as drivers of diverse skin in wound responses.Hindelang, M. ; Kirsch, F. ; Leidl, R.
Effectiveness of non-pharmacological COPD management on health-related quality of life-a systematic review.Rajan, S. ; Weber, J. ; Chao, Y.K. ; Kannler, M. ; Krasteva-Christ, G. ; Yildirim, A.Ö. ; Brosien, M. ; Schredelseker, J. ; Weissmann, N. ; Grimm, C. ; Gudermann, T. ; Dietrich, A.
Essential functions of TRPV4 channels in alveolar epithelium.Giotopoulou, G.A. ; Stathopoulos, G.T.
Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment.Hadrup, N. ; Saber, A.T. ; Kyjovska, Z.O. ; Jacobsen, N.R. ; Vippola, M. ; Sarlin, E. ; Ding, Y. ; Schmid, O. ; Wallin, H. ; Jensen, K.A. ; Vogel, U.
Pulmonary toxicity of Fe2O3, ZnFe2O4, NiFe2O4 and NiZnFe4O8 nanomaterials: Inflammation and DNA strand breaks.Danielsen, P.H. ; Knudsen, K.B. ; Štrancar, J. ; Umek, P. ; Koklič, T. ; Garvas, M. ; Vanhala, E. ; Savukoski, S. ; Ding, Y. ; Madsen, A.M. ; Jacobsen, N.R. ; Weydahl, I.K. ; Berthing, T. ; Poulsen, S.S. ; Schmid, O. ; Wolff, H. ; Vogel, U.
Effects of physicochemical properties of TiO2 nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally exposed mice.Stoecklein, S. ; Hilgendorff, A. ; Li, M. ; Förster, K. ; Flemmer, A.W. ; Galiè, F. ; Wunderlich, S. ; Wang, D. ; Stein, S. ; Ehrhardt, H. ; Dietrich, O. ; Zou, Q. ; Zhou, S. ; Ertl-Wagner, B. ; Liu, H.
Variable functional connectivity architecture of the preterm human brain: Impact of developmental cortical expansion and maturation.Greiffo, F.R. ; Viteri-Alvarez, V. ; Frankenberger, M. ; Dietel, D. ; Ortega-Gomez, A. ; Lee, J.S. ; Hilgendorff, A. ; Behr, J. ; Soehnlein, O. ; Eickelberg, O. ; Fernandez, I.E.
CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases.Jiang, D. ; de Vries, J.C. ; Muschhammer, J. ; Schatz, S. ; Ye, H. ; Hein, T. ; Fidan, M. ; Romanov, V.S. ; Rinkevich, Y. ; Scharffetter-Kochanek, K.
Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing.George, L. ; Taylor, A.R. ; Esteve-Codina, A. ; Soler Artigas, M. ; Thun, G.A. ; Bates, S. ; Pavlidis, S. ; Wagers, S. ; Boland, A. ; Prasse, A. ; Boschetto, P. ; Parr, D.G. ; Nowinski, A. ; Barta, I. ; Hohlfeld, J. ; Greulich, T. ; van den Berge, M. ; Hiemstra, P.S. ; Timens, W. ; Hinks, T. ; Wenzel, S. ; Siddiqui, S. ; Richardson, M. ; Venge, P. ; Heath, S. ; Gut, I. ; Tobin, M.D. ; Edwards, L. ; Riley, J.H. ; Djukanovic, R. ; Auffray, C. ; De-Meulder, B. ; Erik-Dahlen, S. ; Adcock, I.M. ; Chung, K.F. ; Ziegler-Heitbrock, L. ; Sterk, P.J. ; Singh, D. ; Brightling, C.E.
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.Heitmeier, T. ; Sydykov, A. ; Lukas, C. ; Vroom, C. ; Korfei, M. ; Petrovic, A. ; Klingel, K. ; Günther, A. ; Eickelberg, O. ; Weissmann, N. ; Ghofrani, H.A. ; Seeger, W. ; Grimminger, F. ; Schermuly, R.T. ; Meiners, S. ; Kosanovic, D.
Altered proteasome function in right ventricular hypertrophy.Förster, K. ; Ertl-Wagner, B. ; Ehrhardt, H. ; Busen, H. ; Sass, S. ; Pomschar, A. ; Naehrlich, L. ; Schulze, A. ; Flemmer, A.W. ; Hübener, C. ; Eickelberg, O. ; Theis, F.J. ; Dietrich, O. ; Hilgendorff, A.
Altered relaxation times in MRI indicate bronchopulmonary dysplasia.Förster, K. ; Frank, A. ; Ehrhardt, H. ; Hilgendorff, A.
Neue diagnostische Werkzeuge für die frühzeitige Identifikation und strukturelle Charakterisierung der Bronchopulmonalen Dysplasie.Ramsheh, M.Y. ; Thun, G.A. ; Codina, A.E. ; Haldar, K. ; Barer, M. ; Gut, I. ; Ziegler-Heitbrock, L. ; Singh, D. ; Brightling, C.
Prevotella genera abundance in bronchial brush samples differentiates COPD from health and is associated with gene expression.Ramsheh, M.Y. ; Haldar, K. ; Barer, M. ; Ziegler-Heitbrock, L. ; Gut, I. ; Singh, D. ; Brightling, C.
Association between COPD bronchial brush microbiome-determined ?Proteobacteria:Firmicutes (G:F) ratio and GOLD grade and symptoms.Wolff, M. ; El-Merhie, N. ; Reuter, S. ; Goldmann, T. ; Yildirim, A.Ö. ; Fehrenbach, H. ; Krauss-Etschmann, S.
LSC-2019-Relevant murine model to study the development of COPD pathogenesis in smokers with viral infections.Gonzalez, E. ; Zhang, X. ; Oak, P. ; Markmann, M. ; Hilgendorff, A.
Hyperoxia exposure induces age-dependent changes in gene expression in healthy mouse lung.Lehmann, M. ; Mutze, K. ; Hu, Q. ; Königshoff, M.
Late Breaking Abstract - WNT/beta-catenin signaling induces cellular senescence in lung alveolar epithelial cells.Zhang, X. ; Rodriguez, E. ; Markmann, M. ; Oak, P. ; Hilgendorff, A.
Expression profiling of genes differentially regulated under hyperoxia andmechanical ventilation in mouse model of neonatal chronic lung disease.Hardy, S. ; Schneider, A. ; Frankenberger, M. ; Koch, A. ; Milger, K. ; Moulin, C. ; Fievez, M. ; Pilette, C. ; Meiners, S. ; Kammerl, I.E.
LSC-2019-Validating immunoproteasome activity as a potential biomarker in non-invasive samples from COPD patients.Chen, J. ; Brands, J. ; Bueno, M. ; Adler, H. ; Mora, A. ; Meiners, S. ; Kammerl, I.E.
LSC-2019-Effect of cigarette smoke on immunoproteasome function during virus infection.Cyrys, J. ; Schnelle-Kreis, J. ; Kowalski, M. ; Yildirim, A.Ö. ; Schmid, O. ; Stöger, T. ; Peters, A. ; Schneider, A.E. ; Pickford, R. ; Zhang, S. ; Breitner-Busch, S.
Ambient ultrafine particles: Evidence for policy maker.Meul, T. ; Wang, X. ; Angelidis, I. ; Berschneider, K. ; Schmitt, S. ; Zischka, H. ; von Toerne, C. ; Hauck, S.M. ; Schiller, H. B. ; Meiners, S.
Mitochondrial dysfunction activates MHC class I adaptive immune responses in lung aging.Behr, J. ; Wirtz, H. ; Pittrow, D. ; Prasse, A. ; Koschel, D. ; Geier, S. ; Klotsche, J. ; Andreas, S. ; Claussen, M. ; Grohe, C. ; Wilkens, H. ; Hagmeyer, L. ; Skowasch, D. ; Meyer, J.F. ; Kirschner, J. ; Glaeser, S. ; Kahn, N. ; Welte, T. ; Neurohr, C. ; Schwaiblmair, M. ; Held, M. ; Bahmer, T. ; Oqueka, T. ; Frankenberger, M. ; Kreuter, M.
Late Breaking Abstract - Survival and course of lung function in patients with idiopathic pulmonary fibrosis with or without antifibrotic treatment: Long-term results of the INSIGHTS-IPF registry.Morgan, K.S. ; Gradl, R. ; Dierolf, M. ; Jud, C. ; Günther, B. ; Werdiger, F. ; Gardner, M. ; Cmielewski, P. ; McCarron, A. ; Farrow, N. ; Haas, H. ; Kimm, M.A. ; Yang, L. ; Kutschke, D. ; Stöger, T. ; Schmid, O. ; Achterhold, K. ; Pfeiffer, F. ; Parsons, D. ; Donnelley, M.
In vivo x-ray imaging of the respiratory system using synchrotron sources and a compact light source.Thun, G.A. ; Derdak, S. ; Castro-Giner, F. ; Apunte-Ramos, K. ; Águeda, L. ; Wjst, M. ; Boland, A. ; Deleuze, J.F. ; Kolsum, U. ; Heiss-Neumann, M.S. ; Nowinski, A. ; Gorecka, D. ; Hohlfeld, J.M. ; Welte, T. ; Brightling, C.E. ; Parr, D.G. ; Prasse, A. ; Müller-Quernheim, J. ; Greulich, T. ; Stendardo, M. ; Boschetto, P. ; Barta, I. ; Döme, B. ; Gut, M. ; Singh, D. ; Ziegler-Heitbrock, L. ; Gut, I.G.
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.Ulke, H.M. ; Mutze, K. ; Lehmann, M. ; Wagner, D.E. ; Heinzelmann, K. ; Guenther, A. ; Eickelberg, O. ; Königshoff, M.
The oncogene ECT2 contributes to a hyperplastic, proliferative lung epithelial cell phenotype in idiopathic pulmonary fibrosis.Correa-Gallegos, D. ; Jiang, D. ; Christ, S. ; Ramesh, P. ; Ye, H. ; Wannemacher, J. ; Kalgudde Gopal, S. ; Yu, Q. ; Aichler, M. ; Walch, A.K. ; Mirastschijski, U. ; Volz, T. ; Rinkevich, Y.
Patch repair of deep wounds by mobilized fascia.Doll, S. ; Freitas, F.P. ; Shah, R. ; Aldrovandi, M. ; da Silva, M.C. ; Ingold, I. ; Grocin, A.G. ; Xavier da Silva, T.N. ; Panzilius, E. ; Scheel, C. ; Mourao, A. ; Buday, K. ; Sato, M. ; Wanninger, J. ; Vignane, T. ; Mohana, V. ; Rehberg, M. ; Flatley, A. ; Schepers, A. ; Kurz, A. ; White, D. ; Sauer, M. ; Sattler, M. ; Tate, E.W. ; Schmitz, W. ; Schulze, A. ; O’Donnell, V. ; Proneth, B. ; Popowicz, G.M. ; Pratt, D.A. ; Angeli, J.P.F. ; Conrad, M.
FSP1 is a glutathione-independent ferroptosis suppressor.Ramsheh, M.Y. ; Haldar, K. ; Bafadhel, M. ; George, L. ; Free, R.C. ; John, C. ; Reeve, N.F. ; Ziegler-Heitbrock, L. ; Gut, I. ; Singh, D. ; Mistry, V. ; Tobin, M.D. ; Oggioni, M.R. ; Brightling, C. ; Barer, M.R.
Resistome analyses of sputum from COPD and healthy subjects reveals bacterial load-related prevalence of target genes.Giopanou, I. ; Kanellakis, N.I. ; Giannou, A.D. ; Lilis, I. ; Marazioti, A. ; Spella, M. ; Papaleonidopoulos, V. ; Simoes, D.C.M. ; Zazara, D.E. ; Agalioti, T. ; Moschos, C. ; Magkouta, S. ; Kalomenidis, I. ; Panoutsakopoulou, V. ; Lamort, A.-S. ; Stathopoulos, G.T.
Osteopontin drives KRAS-mutant lung adenocarcinoma.Holzwarth, U. ; Cossio, U. ; Llop, J. ; Kreyling, W.G.
Unpredictable nanoparticle retention in commonly used plastic syringes introduces dosage uncertainties that may compromise the accuracy of nanomedicine and nanotoxicology studies.Gulbake, A.S. ; Jain, A. ; Shilpi, S. ; Kumar, P. ; Gulbake, A.
Mannosylated multiwalled carbon nanotubes assisted artesunate delivery for cerebral malaria.Kesireddy, V.S. ; Chillappagari, S. ; Ahuja, S. ; Knudsen, L. ; Henneke, I. ; Graumann, J. ; Meiners, S. ; Ochs, M. ; Ruppert, C. ; Korfei, M. ; Seeger, W. ; Mahavadi, P.
Susceptibility of microtubule-associated protein 1 light chain 3 beta (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.Pang, Y.P. ; Moura, M.C. ; Thompson, G.E. ; Nelson, D.R. ; Hummel, A.M. ; Jenne, D. ; Emerling, D. ; Volkmuth, W. ; Robinson, W.H. ; Specks, U.
Remote activation of a latent epitope in an autoantigen decoded with simulated B-factors.Sarker, R.S. ; Conlon, T.M. ; Morrone, C. ; Srivastava, B. ; Konyalilar, N. ; Verleden, S.E. ; Bayram, H. ; Fehrenbach, H. ; Yildirim, A.Ö.
CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis.Distler, J.H.W. ; Györfi, A.H. ; Ramanujam, M. ; Whitfield, M.L. ; Königshoff, M. ; Lafyatis, R.
Shared and distinct mechanisms of fibrosis.Andrault, P.-M. ; Schamberger, A.C. ; Chazeirat, T. ; Sizaret, D. ; Renault, J. ; Staab-Weijnitz, C.A. ; Hennen, E. ; Petit-Courty, A. ; Wartenberg, M. ; Saidi, A. ; Baranek, T. ; Guyetant, S. ; Courty, Y. ; Eickelberg, O. ; Lalmanach, G. ; Lecaille, F.
Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD.Alhasan, M. ; Cait, A. ; Heimesaat, M.M. ; Blaut, M. ; Klopfleisch, R. ; Yildirim, A.Ö. ; Sodemann, E.B. ; Bereswill, S. ; Conrad, M.L.
Antibiotic use during pregnancy impacts neonatal microbiota composition and increases offspring asthma severity.Arendt, K.A.M. ; Ntaliarda, G. ; Armenis, V. ; Stathopoulos, G.T.
An in vivo inflammatory loop potentiates KRAS blockade.Oplopoiou, M. ; Kati, D. ; Ntaliarda, G. ; Papaleonidopoulos, V. ; Giopanou, I. ; Lilis, I. ; Stathopoulos, G.T.
The role of Trp53 in chemical-induced lung adenocarcinoma.Welk, V. ; Meul, T. ; Lukas, C. ; Kammerl, I.E. ; Mulay, S.R. ; Schamberger, A.C. ; Semren, N. ; Fernandez, I.E. ; Anders, H.J. ; Günther, A. ; Behr, J. ; Eickelberg, O. ; Korfei, M. ; Meiners, S.
Proteasome activator PA200 regulates myofibroblast differentiation.Yang, L. ; Gradl, R. ; Dierolf, M. ; Möller, W. ; Kutschke, D. ; Feuchtinger, A. ; Hehn, L. ; Donnelley, M. ; Günther, B. ; Achterhold, K. ; Walch, A.K. ; Stöger, T. ; Razansky, D. ; Pfeiffer, F. ; Morgan, K.S. ; Schmid, O.
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.Umkehrer, S. ; Birnbacher, L. ; Burkhardt, R. ; Von Teuffenbach, M. ; Yildirim, A.Ö. ; Pfeiffer, D. ; Herzen, J. ; Pfeiffer, F.
Optimization of in vivo murine X-ray dark-field computed tomography.Wang, X. ; Chen, S. ; Ren, H. ; Chen, J. ; Li, J. ; Wang, Y. ; Hua, Y. ; Wang, X. ; Huang, N.
HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization.Tsai, J.M. ; Shoham, M. ; Fernhoff, N.B. ; George, B.M. ; Marjon, K.D. ; McCracken, M.N. ; Kao, K.S. ; Sinha, R. ; Volkmer, A.K. ; Miyanishi, M. ; Seita, J. ; Rinkevich, Y. ; Weissman, I.L.
Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation.Marazioti, A. ; Papadia, K. ; Kannavou, M. ; Spella, M. ; Basta, A. ; de Lastic, A.L. ; Rodi, M. ; Mouzaki, A. ; Samiotaki, M. ; Panayotou, G. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Cellular vesicles: New insights in engineering methods, interaction with cells and potential for brain targeting.Lamort, A.-S. ; Hamon, Y. ; Czaplewski, C. ; Gieldon, A. ; Seren, S. ; Coquet, L. ; Lecaille, F. ; Lesner, A. ; Lalmanach, G. ; Gauthier, F. ; Jenne, D. ; Korkmaz, B.
Processing and maturation of cathepsin C zymogen: A biochemical and molecular modeling analysis.Wang, H. ; Wei, Y. ; Pu, Y. ; Jiang, D. ; Jiang, X. ; Zhang, Y. ; Tao, J.
Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity.Thompson, G. ; Moura, M.C. ; Nelson, D. ; Fussner, L. ; Hummel, A. ; Jenne, D. ; Fervenza, F. ; Hoffman, G. ; Kallenberg, C. ; Langford, C. ; McCune, J. ; Merkel, P. ; Monach, P. ; Seo, P. ; Spiera, R. ; St Clair, E.W. ; Ytterberg, S. ; Stone, J. ; Robinson, W. ; Pang, Y. ; Specks, U.
Preferential binding to an unexpected epitope of a chimeric recombinant proteinase 3 variant by anti-neutrophil cytoplasmic antibodies.Lamort, A.-S. ; Giopanou, I. ; Psallidas, I. ; Stathopoulos, G.T.
Osteopontin as a link between inflammation and cancer: The thorax in the spotlight.Fei, Y. ; Liu, X. ; Mu, J. ; Li, J. ; Yu, X. ; Chang, J. ; Bi, Y. ; Stöger, T. ; Wajid, A. ; Muzyka, D. ; Sharshov, K. ; Shestopalov, A. ; Amonsin, A. ; Chen, J. ; Ding, Z. ; Yin, R.
The emergence of avian orthoavulavirus 13 in wild migratory waterfowl in China revealed the existence of diversified trailer region sequences and HN gene lengths within this serotype.Zhu, Y. ; Cao, Z. ; Peng, Y. ; Hu, L. ; Güney, T. ; Tang, B.
Facile surface modification method for synergistically enhancing the biocompatibility and bioactivity of poly(ether ether ketone) that induced osteodifferentiation.Nikolić, M.Z. ; Garrido-Martin, E.M. ; Greiffo, F.R. ; Fabre, A. ; Heijink, I.H. ; Boots, A. ; Greene, C.M. ; Hiemstra, P.S. ; Bartel, S.
From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 "Basic and Translational Science.".Doryab, A. ; Tas, S. ; Taskin, M.B. ; Yang, L. ; Hilgendorff, A. ; Groll, J. ; Wagner, D.E. ; Schmid, O.
Evolution of bioengineered lung models: Recent advances and challenges in tissue mimicry for studying the role of mechanical forces in cell biology.Merl-Pham, J. ; Basak, T. ; Knüppel, L. ; Ramanujam, D. ; Athanason, M. ; Behr, J. ; Engelhardt, S. ; Eickelberg, O. ; Hauck, S.M. ; Vanacore, R. ; Staab-Weijnitz, C.A.
Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro model of lung fibrosis.Förster, K. ; Herber-Jonat, S. ; Florian, A. ; Klemme, M. ; Flemmer, A.W.
Langzeitentwicklung von Kindern nach Extra Corporaler Membran Oxygenierung (ECMO).Ng-Blichfeldt, J.P. ; de Jong, T. ; Kortekaas, R.K. ; Wu, X. ; Lindner, M. ; Guryev, V. ; Hiemstra, P.S. ; Stolk, J. ; Königshoff, M. ; Gosens, R.
TGF-beta activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.Kreyling, W.G. ; Holzwarth, U. ; Schleh, C. ; Hirn, S. ; Wenk, A. ; Schäffler, M. ; Haberl, N. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics over a 28day period of freshly generated, pristine, 20 nm titanium dioxide nanoparticle aerosols in healthy adult rats after a single two-hour inhalation exposure.Rehm, S.R.T. ; Smirnova, N.F. ; Morrone, C. ; Götzfried, J. ; Feuchtinger, A. ; Pedersen, J. ; Korkmaz, B. ; Yildirim, A.Ö. ; Jenne, D.
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.Fernandez, I.M. ; Macrini, C. ; Krumbholz, M. ; Hensbergen, P.J. ; Ederveen, A.L.H. ; Winklmeier, S. ; Vural, A. ; Kurne, A. ; Jenne, D. ; Kamp, F. ; Gerdes, L.A. ; Hohlfeld, R. ; Wuhrer, M. ; Kuempfel, T. ; Meinl, E.
The glycosylation site of myelin oligodendrocyte glycoprotein affects autoantibody recognition in a large proportion of patients.Gradl, R. ; Dierolf, M. ; Yang, L. ; Hehn, L. ; Günther, B. ; Möller, W. ; Kutschke, D. ; Stöger, T. ; Gleich, B. ; Achterhold, K. ; Donnelley, M. ; Pfeiffer, F. ; Schmid, O. ; Morgan, K.S.
Visualizing treatment delivery and deposition in mouse lungs using in vivo x-ray imaging.Yu, S. ; Zhang, Y. ; Zhao, X. ; Chang, Z. ; Wei, Y. ; Sun, Y. ; Jiang, D. ; Jiang, X. ; Tao, J.
Cholecystokinin type B receptor-mediated inhibition of A-type K+ channels enhances sensory neuronal excitability through the phosphatidylinositol 3-kinase and c-Src-dependent JNK pathway.Farnoud, A. ; Orak, S. ; Schmid, O.
Numerical models of respiratory drug deposition and pharmacokinetics: Application to liposomal ciclosporin a (L-CSA).Schmid, O.
Advanced in vitro and in silico models improve predictions of in vivo/clinical pharmacokinetics of nanocarrier-laden inhaled drugs.Yang, L. ; Gradl, R. ; Feuchtinger, A. ; Morgan, K.S. ; Kutschke, D. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Pfeiffer, F. ; Schmidt, O.
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.Klotz, L.V. ; Lindner, M. ; Eichhorn, M.E. ; Grützner, U. ; Koch, I. ; Winter, H. ; Kauke, T. ; Duell, T. ; Hatz, R.
Pleurectomy/decortication and hyperthermic intrathoracic chemoperfusion using cisplatin and doxorubicin for malignant pleural mesothelioma.Orak, S. ; Rothen-Rutishauser, B. ; Jud, C. ; Farnoud, A. ; Bucholski, A. ; Egle, R. ; Boerner, G. ; Denk, O. ; Schmid, O.
Towards prediction of the pharmacokinetics of inhaled nanomedicine from physiological cell models: A case study with liposomal ciclosporin A (L-CSA) using the vitrocell cloud system.Marazioti, A. ; Papadia, K. ; Giannou, A. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection.Merrick, C. ; Sherrill, T. ; Kanellakis, N.I. ; Asciak, R. ; Stathopoulos, G.T. ; Maldonado, F. ; Rahman, N.M. ; Blackwell, T. ; Psallidas, I.
Novel mouse model of indwelling pleural catheter in mice with malignant pleural effusion.Spella, M. ; Lilis, I. ; Pepe, M. ; Chen, Y. ; Armaka, M. ; Lamort, A.-S. ; Zazara, D.E. ; Roumelioti, F. ; Vreka, M. ; Kanellakis, N.I. ; Wagner, D.E. ; Giannou, A.D. ; Armenis, V. ; Arendt, K.A.M. ; Klotz, L.V. ; Toumpanakis, D. ; Karavana, V. ; Zakynthinos, S.G. ; Giopanou, I. ; Marazioti, A. ; Aidinis, V. ; Sotillo, R. ; Stathopoulos, G.T.
Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.Conlon, T.M. ; Güneş, G. ; Sarker, R.S. ; Fehrenbach, H. ; Yildirim, A.Ö.
Arginine methylation epigenetically regulates airway epithelial cell injury in COPD pathogenesis.Srivastava, B. ; Conlon, T.M. ; Mitula, E. ; Sarker, R.S. ; Yildirim, A.Ö.
Developing oxysterol inhibitors as a novel therapeutic target for iBALT driven chronic pulmonary diseases.Gunsel, G.G. ; Conlon, T.M. ; Sarker, R. ; Jia, J. ; Heinzelmann, K. ; Tasdemir, D. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Metabolomic regulation of B cells drives the pathogenesis of COPD.Staab-Weijnitz, C.A. ; Merl-Pham, J. ; Basak, T. ; Knüppel, L. ; Ramanujam, D. ; Athanason, M. ; Behr, J. ; Engelhardt, S. ; Eickelberg, O. ; Hauck, S.M. ; Vanacore, R.
Quantitative proteomic profiling of extracellular matrix and collagen posttranslational modifications in an in vitro model of lung fibrosis.Heinzelmann, K. ; Ulke, H.M. ; Mutze, K. ; Wagner, D.E. ; Ren, W. ; Guenther, A. ; Eickelberg, O. ; Koenigshoff, M.
Epithelial cell transforming sequence 2 contributes to alveolar epithelial cell reprogramming in idiopathic pulmonary fibrosis.Fernandez, I.E. ; Greiffo, F.R. ; Viteri-Alvarez, V. ; Bastidas, I. ; Roy, R. ; Frankenberger, M. ; Behr, J. ; Forrest, A. ; Hilgendorff, A. ; Eickelberg, O.
Myeloid-derived suppressor cells orchestrate immunosuppressive networks in idiopathic pulmonary fibrosis.Lehmann, M. ; Klee, S. ; Wagner, D.E. ; Koenigshoff, M.
Wnt1-inducible signaling protein 1 (WISP1) augments nuclear factor (NF)-kB signaling in primary human lung fibroblasts.Bölükbas, D.A. ; Morrone, C. ; Doryab, A. ; Datz, S. ; Gößl, D. ; Meyer-Schwickerath, C. ; Vreka, M. ; van Rijt, S.H. ; Stöger, T. ; Stathopoulos, G.T. ; Lindstedt, S. ; Bein, T. ; Meiners, S. ; Wagner, D.E.
Fine-tuning lung cancer nanotherapy using closed cardiopulmonary circulation.Halappanavar, S. ; Rahman, L. ; Nikota, J. ; Poulsen, S.S. ; Ding, Y. ; Jackson, P. ; Wallin, H. ; Schmid, O. ; Vogel, U. ; Williams, A.
Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses.Moore, C. ; Blumhagen, R.Z. ; Yang, I.V. ; Walts, A. ; Powers, J. ; Walker, T. ; Bishop, M. ; Russell, P. ; Vestal, B. ; Cardwell, J. ; Markin, C.R. ; Mathai, S.K. ; Schwarz, M.I. ; Steele, M.P. ; Lee, J. ; Brown, K.K. ; Loyd, J.E. ; Crapo, J.D. ; Silverman, E.K. ; Cho, M.H. ; James, J.A. ; Guthridge, J.M. ; Cogan, J.D. ; Kropski, J.A. ; Swigris, J.J. ; Bair, C. ; Soon Kim, D. ; Ji, W. ; Kim, H. ; Song, W.J. ; Maier, L.A. ; Pacheco, K.A. ; Hirani, N. ; Poon, A.S. ; Li, F. ; Jenkins, R.G. ; Braybrooke, R. ; Saini, G. ; Maher, T.M. ; Molyneaux, P.L. ; Saunders, P. ; Zhang, Y. ; Gibson, K.F. ; Kass, D.J. ; Rojas, M. ; Sembrat, J. ; Wolters, P.J. ; Collard, H.R. ; Sundy, J.S. ; O'Riordan, T. ; Strek, M.E. ; Noth, I. ; Ma, S.F. ; Porteous, M.K. ; Kreider, M.E. ; Patel, N.B. ; Inoue, Y. ; Hirose, M. ; Arai, T. ; Akagawa, S. ; Eickelberg, O. ; Fernandez, I.E. ; Behr, J. ; Mogulkoc, N. ; Corte, T.J. ; Glaspole, I. ; Tomassetti, S. ; Ravaglia, C. ; Poletti, V. ; Crestani, B. ; Borie, R. ; Kannengiesser, C. ; Parfrey, H. ; Fiddler, C. ; Rassl, D. ; Molina-Molina, M. ; Machahua, C. ; Montes Worboys, A. ; Gudmundsson, G. ; Isaksson, H.J. ; Lederer, D.J. ; Podolanczuk, A.J. ; Montesi, S.B. ; Bendstrup, E. ; Danchel, V. ; Selman, M. ; Pardo, A. ; Henry, M.T. ; Keane, M.P. ; Doran, P. ; Vašáková, M. ; Sterclova, M. ; Ryerson, C.J. ; Wilcox, P.G. ; Okamoto, T. ; Furusawa, H. ; Miyazaki, Y. ; Laurent, G. ; Baltic, S. ; Prele, C. ; Moodley, Y. ; Shea, B.S. ; Ohta, K. ; Suzukawa, M. ; Narumoto, O. ; Nathan, S.D. ; Venuto, D.C. ; Woldehanna, M.L. ; Kokturk, N. ; de Andrade, J.A. ; Luckhardt, T. ; Kulkarni, T. ; Bonella, F. ; Donnelly, S.C. ; McElroy, A. ; Armstrong, M.E. ; Aranda, A. ; Carbone, R.G. ; Puppo, F. ; Beckman, K.B. ; Nickerson, D.A. ; Fingerlin, T.E. ; Schwartz, D.A.
Resequencing study confirms host defense and cell senescence gene variants contribute to the risk of idiopathic pulmonary fibrosis.Ballester-Lopez, C. ; Conlon, T.M. ; Ertüz, Z. ; Greiffo, F.R. ; Irmler, M. ; Verleden, S.E. ; Beckers, J. ; Fernandez, I.E. ; Eickelberg, O. ; Yildirim, A.Ö.
The Notch ligand DNER regulates macrophage IFN gamma release in chronic obstructive pulmonary disease.Modic, M. ; Grosch, M. ; Rot, G. ; Schirge, S. ; Lepko, T. ; Yamazaki, T. ; Lee, F.C.Y. ; Rusha, E. ; Shaposhnikov, D. ; Palo, M. ; Merl-Pham, J. ; Cacchiarelli, D. ; Rogelj, B. ; Hauck, S.M. ; von Mering, C. ; Meissner, A. ; Lickert, H. ; Hirose, T. ; Ule, J. ; Drukker, M.
Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition.Mascalzoni, D. ; Bentzen, H.B. ; Budin-Ljøsne, I. ; Bygrave, L.A. ; Bell, J. ; Dove, E.S. ; Fuchsberger, C. ; Hveem, K. ; Mayrhofer, M.T. ; Meraviglia, V. ; O'Brien, D.R. ; Pattaro, C. ; Pramstaller, P.P. ; Rakic, V. ; Rossini, A. ; Shabani, M. ; Svantesson, D.J.B. ; Tomasi, M. ; Ursin, L. ; Wjst, M. ; Kaye, J.
Are requirements to deposit data in research repositories compatible with the european union's general data protection regulation?Lilis, I. ; Ntaliarda, G. ; Papaleonidopoulos, V. ; Giotopoulou, G.A. ; Oplopoiou, M. ; Marazioti, A. ; Spella, M. ; Marwitz, S. ; Goldmann, T. ; Bravou, V. ; Giopanou, I. ; Stathopoulos, G.T.
Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma.Wjst, M.
We are still confused but on a higher level.Vetrivel, S. ; Tiso, N. ; Kügler, A. ; Irmler, M. ; Horsch, M. ; Beckers, J. ; Hladik, D. ; Giesert, F. ; Gailus-Durner, V. ; Fuchs, H. ; Sabrautzki, S. ; Adler, T. ; Treise, I. ; Busch, D.H. ; Aguilar-Pimentel, J.A. ; Ollert, M. ; Götz, A. ; Amarie, O.V. ; Stöger, T. ; Schulz, H. ; Becker, L. ; Klopstock, T. ; Schrewe, A. ; Spielmann, N. ; Bekeredjian, R. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Mayer-Kuckuk, P. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Neff, F. ; da Silva Buttkus, P. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Prehn, C. ; Adamski, J. ; Östereicher, M.A. ; Miller, G. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Hrabě de Angelis, M. ; Graw, J.
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.Kerdidani, D. ; Chouvardas, P. ; Arjo, A.R. ; Giopanou, I. ; Ntaliarda, G. ; Guo, Y.A. ; Tsikitis, M. ; Kazamias, G. ; Potaris, K. ; Stathopoulos, G.T. ; Zakynthinos, S. ; Kalomenidis, I. ; Soumelis, V. ; Kollias, G. ; Tsoumakidou, M.
Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma.Morrone, C. ; Smirnova, N.F. ; Kneidinger, N. ; Schiller, H. B. ; Eickelberg, O. ; Yildirim, A.Ö.
Elevetad cysteine-protease activity in bronchiolitis obliterans syndrome.Jiang, D. ; Christ, S. ; Gallegos, D.C. ; Ramesh, P. ; Gopal, S.K. ; Yu, Q. ; Mayr, C. ; Lupperger, V. ; Liu, J. ; Marr, C. ; Schiller, H. B. ; Rinkevich, Y.
Visualizing scar development in living tissues reveals the collective migration of fibroblasts mediated by N-cadherin.Castelletti, N. ; Kaiser, J.C. ; Simonetto, C. ; Furukawa, K. ; Küchenhoff, H. ; Stathopoulos, G.T.
Risk of lung adenocarcinoma from smoking and radiation arises in distinct molecular pathways.Gerckens, M. ; Alsafadi, H.N. ; Wagner, D.E. ; Lindner, M. ; Burgstaller, G. ; Königshoff, M.
Generation of human 3D lung tissue cultures (3D-LTCs) for disease modeling.Kanellakis, N.I. ; Giannou, A.D. ; Pepe, M. ; Αgalioti, T. ; Zazara, D.E. ; Giopanou, I. ; Psallidas, I. ; Spella, M. ; Μarazioti, A. ; Arendt, K.A.M. ; Lamort, A.-S. ; Tsaniras, S.C. ; Taraviras, S. ; Papadaki, H. ; Lilis, I. ; Stathopoulos, G.T.
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.Kunze, F.A. ; Bauer, M. ; Komuczki, J. ; Lanzinger, M. ; Gunasekera, K. ; Hopp, A.K. ; Lehmann, M. ; Becher, B. ; Müller, A. ; Hottiger, M.O.
ARTD1 in myeloid cells controls the IL-12/18-IFN-γ axis in a model of sterile sepsis, chronic bacterial infection, and cancer.Klotz, L.V. ; Courty, Y. ; Lindner, M. ; Petit-Courty, A. ; Stowasser, A. ; Koch, I. ; Eichhorn, M.E. ; Lilis, I. ; Morresi-Hauf, A. ; Arendt, K.A.M. ; Pepe, M. ; Giopanou, I. ; Ntaliarda, G. ; Behrend, S.J. ; Oplopoiou, M. ; Gissot, V. ; Guyetant, S. ; Marchand-Adam, S. ; Behr, J. ; Kaiser, J.C. ; Hatz, R.A. ; Lamort, A.-S. ; Stathopoulos, G.T.
Comprehensive clinical profiling of the Gauting locoregional lung adenocarcinoma donors.Krampitz, G.W. ; Tsai, J. ; Norton, J.A. ; Weissman, I.L. ; Rinkevich, Y.
Adhesions are derived from hypoxia responsive mesothelin-positive mesothelial cells and are resolved via targeted therapies.Bölükbas, D.A. ; De Santis, M.M. ; Alsafadi, H.N. ; Doryab, A. ; Wagner, D.E.
The preparation of decellularized mouse lung matrix scaffolds for analysis of lung regenerative cell potential.Smirnova, N.F. ; Conlon, T.M. ; Morrone, C. ; Dorfmuller, P. ; Humbert, M. ; Stathopoulos, G.T. ; Umkehrer, S. ; Pfeiffer, F. ; Yildirim, A.Ö. ; Eickelberg, O.
Inhibition of B cell–dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation.Zhang, Y. ; Jiang, D. ; Li, H. ; Sun, Y. ; Jiang, X. ; Gong, S. ; Qian, Z. ; Tao, J.
Melanocortin type 4 receptor-mediated inhibition of A-type K+ current enhances sensory neuronal excitability and mechanical pain sensitivity in rats.Hsiao, I.L. ; Fritsch-Decker, S. ; Leidner, A. ; Al-Rawi, M. ; Hug, V. ; Diabaté, S. ; Grage, S.L. ; Meffert, M. ; Stöger, T. ; Gerthsen, D. ; Ulrich, A.S. ; Niemeyer, C.M. ; Weiss, C.
Biocompatibility of amine-functionalized silica nanoparticles: The role of surface coverage.Angelidis, I. ; Simon, L. ; Fernandez, I.E. ; Strunz, M. ; Mayr, C. ; Greiffo, F.R. ; Tsitsiridis, G. ; Ansari, M. ; Graf, E. ; Strom, T.M. ; Nagendran, M. ; Desai, T. ; Eickelberg, O. ; Mann, M. ; Theis, F.J. ; Schiller, H. B.
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics.von Siemens, S.M. ; Jörres, R.A. ; Behr, J. ; Alter, P. ; Lutter, J. ; Lucke, T. ; Söhler, S. ; Welte, T. ; Watz, H. ; Vogelmeier, C.F. ; Trudzinski, F. ; Rief, W. ; Herbig, B. ; Kahnert, K.
Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: Results from the COSYCONET cohort study.Stöger, T. ; Adler, H.
"Novel" triggers of herpesvirus reactivation and their potential health relevance.Kylafis, G.F. ; Sleigh, P.A. ; Tomlin, A.S. ; Ding, Y.
Evacuation characteristics of released airborne TiO2 nanomaterial particles under different ventilation rates in a confined environment.Kammerl, I.E. ; Caniard, A. ; Merl-Pham, J. ; Ben-Nissan, G. ; Mayr, C.H. ; Mossina, A. ; Geerlof, A. ; Eickelberg, O. ; Hauck, S.M. ; Sharon, M. ; Meiners, S.
Dissecting the molecular effects of cigarette smoke on proteasome function.Yang, L. ; Feuchtinger, A. ; Möller, W. ; Ding, Y. ; Kutschke, D. ; Möller, G. ; Schittny, J.C. ; Burgstaller, G. ; Hofmann, W. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Schmid, O.
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.Yamano, T. ; Steinert, M. ; Steer, B. ; Klein, L. ; Hammerschmidt, W. ; Adler, H.
B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?Lau, M.Y.Z. ; Dharmage, S.C. ; Burgess, J.A. ; Win, A.K. ; Lowe, A.J. ; Lodge, C.J. ; Perret, J. ; Hui, J. ; Thomas, P.S. ; Giles, G. ; Thompson, B.R. ; Abramson, M.J. ; Walters, E.H. ; Matheson, M.C. ; Collaboration (Wjst, M.)
Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization.Gao, C. ; Ding, Z. ; Qian, J. ; Liu, X. ; Zhang, X. ; Cong, Y. ; Ding, C. ; Yu, S. ; Hu, S. ; Stöger, T. ; Yin, R.
The virulence of NDV NA-1 strain regulated by the 3 ' leader or 5 ' trailer sequences.Gradl, R. ; Morgan, K.S. ; Dierolf, M. ; Jud, C. ; Hehn, L. ; Günther, B. ; Möller, W. ; Kutschke, D. ; Yang, L. ; Stöger, T. ; Pfeiffer, D. ; Gleich, B. ; Achterhold, K. ; Schmid, O. ; Pfeiffer, F.
Dynamic in vivo chest x-ray dark field imaging in mice.Welk, V.
Dissecting the role of proteasome activators in lung biology and disease.Pepe, M. ; Pelizza, F. ; Lamort, A. ; Kanellakis, N.I. ; Stathopoulos, G.T.
Alteration patterns of tobacco carcinogens in lung adenocarcinoma reveal novel KRAS-addicted candidate oncogenes.Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Eickelberg, O.
Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging.De Santis, M. ; Ota, C. ; Costa, R. ; Doryab, A. ; Alsafadi, H.N. ; Bolukbas, D. ; Königshoff, M. ; Wagner, D.
Development of a hybrid alginate-ECM hydrogel as a potential bioink for 3D bioprinting.Welk, V. ; Meul, T. ; Lukas, C. ; Bolukbas, D. ; Koch, I. ; Lindner, M. ; Meiners, S.
Analyzing the role of proteasome activator 200 (PA200) in lung cancer.Knüppel, L. ; Heinzelmann, K. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FKBP10 regulates fibroblast migration via synthesis of collagen VI.Lamort, A. ; Weiss, S. ; Lillis, I. ; Armenis, V. ; Arendt, K.A.M. ; Pepe, M. ; Klotz, L.V. ; Marazioti, A. ; Spella, M. ; Giopanou, I. ; Ntaliarda, G. ; Giotopoulou, G.A. ; Lianou, M. ; Oplopoiou, M. ; Kauka, K. ; Jenne, D. ; Stathopoulos, G.T.
Tumor-derived granulocyte chemotactic protein 2 cooperates with neutrophil proteinase 3 to drive lung adenocarcinoma.Fernandez, I.E. ; Greiffo, F.R. ; Roi, R. ; Behr, J. ; Forrest, A.R. ; Eickelberg, O.
Circulating MDSC modulate IPF progression by orchestrating immunosuppressive and pro-fibrotic networks.Lambert, K.A. ; Lodge, C. ; Prendergast, L.A. ; Bowatte, G. ; Lowe, A. ; Wjst, M. ; Abramson, M.J. ; Dharmage, S.C. ; Erbas, B.
Associations between early life exposure to pollen and adolescent lung function are modified by residential greenness.Costa, R. ; Wagner, D.E. ; De Santis, M. ; Bailey, K.E. ; Doryab, A. ; Schorpp, K.K. ; Rothenaigner, I. ; Ota, C. ; Baarsma, H.A. ; Campillos, M.J. ; Hadian, K. ; Königshoff, M.
Novel compounds for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease.Wartenberg, M. ; Andrault, P. ; Schamberger, A.C. ; Chazeirat, T. ; Sizaret, D. ; Renault, J. ; Petit, A. ; Saidi, A. ; Guyetant, S. ; Courty, Y. ; Eickelberg, O. ; Lalmanach, G. ; Lecaille, F.
Cigarette smoke induces overexpression of cathepsin S in active smokers with and without COPD.Kindt-Dunjko, A. ; Foerster, K. ; Flemmer, A. ; Oak, P. ; Pomschar, A. ; Ertl-Wagner, B. ; Krumsiek, J. ; Hilgendorff, A.
Late Breaking Abstract - Protein signature stratifies severity of chronic lung disease in preterms after birth.Lopez, C.B. ; Conlon, T.M. ; Ertuz, Z. ; Eickelberg, O. ; Yildirim, A.Ö.
The novel notch ligand DNER modulates IFN. Levels in recruited macrophages by enhancing non-canonical notch during COPD progression.Lehmann, M. ; Klee, S. ; Kaufmann, G. ; Koenigshoff, M.
Human anti-Wnt1-inducible signaling protein (WISP) 1 antibodies attenuate experimental lung fibrosis ex vivo.Schmid, O. ; Möller, W. ; Stelzl, A. ; Lund, J. ; Yildirim, A.Ö. ; Krauss-Etschmann, S. ; Robichaud, A.
Preclinical experiments support recent clinical switch to delivered dose during methacholine bronchoprovocation testing.Smirnova, N.F. ; Morrone, C. ; Conlon, T.M. ; von Toerne, C. ; Hauck, S.M. ; Eickelberg, O. ; Yildirim, A.Ö.
A quantitative proteomics profiling of murine lung grafts indicates novel pathways associated with chronic lung allograft dysfunction.Knüppel, L. ; Merl-Pham, J. ; Hennen, E. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Hauck, S.M. ; Staab-Weijnitz, C.A.
A proteomic analysis of extracellular matrix from idiopathic pulmonary fibrosis patient-derived fibroblasts in response to transforming growth factor beta 1.Tsai, J.M. ; Sinha, R. ; Seita, J. ; Fernhoff, N. ; Christ, S. ; Koopmans, T. ; Krampitz, G.W. ; McKenna, K.M. ; Xing, L. ; Sandholzer, M. ; Sales, J.H. ; Shoham, M. ; McCracken, M. ; Joubert, L.M. ; Gordon, S.R. ; Poux, N. ; Wernig, G. ; Norton, J.A. ; Weissman, I.L. ; Rinkevich, Y.
Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers.Morrone, C. ; Smirnova, N.F. ; Kneidinger, N. ; Mann, M. ; Schiller, H.B. ; Eickelberg, O. ; Yildirim, A.Ö.
Increased peribronchiolar and perivascular cysteine protease activity is associated with bronchiolitis obliterans syndrome.Schittny, J.C. ; Möller, W. ; Holzwarth, U. ; Hirn, S. ; Wenk, A. ; Schleh, C. ; Schäffler, M. ; Haberl, N. ; Gibson, N. ; Kreyling, W.G.
Age-dependent deposition patterns and quantitative biokinetics of inhaled 20nm gold nanoparticles in rat lungs.Conlon, T.M. ; Sarker, R.S. ; Jia, J. ; Heinzelmann, K. ; Tasdemir, D. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Immuno-metabolomic regulation of B cell guided iBALT positioning drives cigarette smoke-induced COPD.Foerster, K. ; Ertl-Wagner, B. ; Sass, S. ; Stoecklein, S. ; Schoeppe, F. ; Dietrich, O. ; Pomschar, A. ; Schulze, A. ; Huebener, C. ; Theis, F.J. ; Ehrhardt, H. ; Flemmer, A. ; Hilgendorff, A.
Quantitative MRI measurements to detect pulmonary hypertension in bronchopulomnary dysplasia.Hu, Y. ; Skronska-Wasek, W. ; Ota, C. ; Mutze, K. ; Baarsma, H.A. ; Wagner, D.E. ; Lehmann, M. ; Bracke, K.R. ; Brusselle, G.G. ; Yildirim, A.Ö. ; Koenigshoff, M.
The progenitor cell marker LGR5 is reduced in epithelial cells in emphysema.Foerster, K. ; Sass, S. ; Pomschar, A. ; Ehrhardt, H. ; Naehrlich, L. ; Schulze, A. ; Flemmer, A. ; Huebener, C. ; Eickelberg, O. ; Theis, F.J. ; Dietrich, O. ; Ertl-Wagner, B. ; Hilgendorff, A.
Diagnosis of bronchopulmonary dysplasia using magnetic resonance imaging analysis.Heinzelmann, K. ; Gerckens, M. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Hilgendorff, A.
DPPIV expression in human lung fibroblasts affects phenotypic changes in fibrosis.Oak, P. ; Koschlig, M. ; Pritzke, T. ; Foerster, K. ; Ahnert, P. ; Windhorst, A. ; Reicherzer, T. ; Ehrhardt, H. ; Hilgendorff, A.
Gender specific response of the neonatal lung to postnatal injury.Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone treatment in pulmonary fibrosis detected by high resolution MALDI FTICR-mass spectrometry imaging.Preisendörfer, S. ; Knüppel, L. ; Ishikawa, Y. ; Binzenhöfer, L. ; Fernandez, I.E. ; Juan-Guardela, B.M. ; Ruppert, C. ; Guenther, A. ; Hatz, R. ; Behr, J. ; Kaminski, N. ; Schepers, A. ; Bachinger, H. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FK506 binding protein 11, a plasma cell-specific antibody folding catalyst, is increased in pulmonary fibrosis.Costa, R. ; Wagner, D.E. ; De Santis, M. ; Bailey, K.E. ; Doryab, A. ; Schorpp, K.K. ; Rothenaigner, I. ; Ota, C. ; Baarsma, H.A. ; Campillos, M. ; Hadian, K. ; Koenigshoff, M.
Drug repurposing for WNT/beta-catenin induced lung repair in chronic obstructive pulmonary disease.Mahmutovic, L. ; Akcesme, B. ; Durakovic, C. ; Akcesme, F.B. ; Maric, A. ; Adilovic, M. ; Hamad, N. ; Wjst, M. ; Feeney, O. ; Semiz, S.
Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine.Jiang, D. ; Rinkevich, Y.
Defining skin fibroblastic cell types beyond CD90.Matthes, S. ; Stadler, J. ; Barton, J. ; Leuschner, G. ; Munker, D. ; Arnold, P. ; Villena-Hermoza, H. ; Frankenberger, M. ; Probst, P. ; Koch, A. ; Kneidinger, N. ; Milger, K. ; Behr, J. ; Neurohr, C.
Asthma features in severe COPD: Identifying treatable traits.Thompson, G.A. ; Moura, M.C. ; Nelson, D. ; Hummel, A.M. ; Jenne, D. ; Fervenza, F. ; Hoffman, G.S. ; Kallenberg, C.G.M. ; Langford, C. ; McCune, J.W. ; Merkel, P.A. ; Monach, P.A. ; Seo, P. ; Spiera, R.F. ; St Clair, E.W. ; Ytterberg, S.R. ; Stone, J.H. ; Robinson, W.H. ; Pang, Y. ; Specks, U.
Characterization of preferential recognition of a chimeric recombinant proteinase 3 variant by anti-neutrophil cytoplasmic antibodies.Ghosh, S. ; Drexler, I. ; Bhatia, S. ; Adler, H. ; Gennery, A.R. ; Borkhardt, A.
Interleukin-2-inducible T-cell kinase deficiency-new patients, new insight?Koopmans, T. ; Rinkevich, Y.
Mesothelial to mesenchyme transition as a major developmental and pathological player in trunk organs and their cavities.Ghosh, S. ; Drexler, I. ; Bhatia, S. ; Adler, H. ; Gennery, A.R. ; Borkhardt, A.
Erratum: Corrigendum: Interleukin-2-inducible T-cell kinase deficiency-new patients, new insight? (Frontiers in immunology (2018) 9 (979)).Oplopoiou, M. ; Kati, D. ; Ntaliarda, G. ; Giopanou, I. ; Papaleonidopoulos, V. ; Lilis, I. ; Stathopoulos, G.T.
Trp53 signaling in chemically induced lung adenocarcinoma.Ng-Blichfeldt, J.P. ; Schrik, A. ; Kortekaas, R.K. ; Noordhoek, J.A. ; Heijink, I.H. ; Hiemstra, P.S. ; Stolk, J. ; Königshoff, M. ; Gosens, R.
Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.Magkouta, S. ; Kollintza, A. ; Moschos, C. ; Spella, M. ; Skianis, I. ; Pappas, A. ; Vazakidou, M.E. ; Stathopoulos, G.T. ; Kalomenidis, I.
Role of angiopoietins in mesothelioma progression.Kreyling, W.G. ; Möller, W. ; Holzwarth, U. ; Hirn, S. ; Wenk, A. ; Schleh, C. ; Schäffler, M. ; Haberl, N. ; Gibson, N. ; Schittny, J.C.
Age-dependent rat lung deposition patterns of inhaled 20 manometer gold nanoparticles and their quantitative biokinetics in adult rats.Chen, Y. ; Ding, Z. ; Liu, X. ; Chen, J. ; Li, J. ; Fei, Y. ; Liu, Z. ; Stöger, T. ; Bi, Y. ; Yin, R.
Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China.Prange, R. ; Thiedmann, M. ; Bhandari, A. ; Mishra, N. ; Sinha, A. ; Häsler, R. ; Rosenstiel, P. ; Uliczka, K. ; Wagner, C. ; Yildirim, A.Ö. ; Fink, C. ; Roeder, T.
A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention.Roth, C.J. ; Förster, K. ; Hilgendorff, A. ; Ertl-Wagner, B. ; Wall, W.A. ; Flemmer, A.W.
Gas exchange mechanisms in preterm infants on HFOV - a computational approach.Lehmann, M. ; Buhl, L. ; Alsafadi, H.N. ; Klee, S. ; Hermann, S. ; Mutze, K. ; Ota, C. ; Lindner, M. ; Behr, J. ; Hilgendorff, A. ; Wagner, D.E. ; Königshoff, M.
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.Ota, C. ; Ng-Blichfeldt, J.P. ; Korfei, M. ; Alsafadi, H.N. ; Lehmann, M. ; Skronska-Wasek, W. ; De Santis, M. ; Guenther, A. ; Wagner, D.E. ; Königshoff, M.
Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis.De Santis, M. ; Bolukbas, D.A. ; Lindstedt, S. ; Wagner, D.E.
How to build a lung: Latest advances and emerging themes in lung bioengineering.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Witting, M. ; Aichler, M. ; Feuchtinger, A. ; Burgstaller, G. ; Verleden, S.E. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.Martin-Medina, A. ; Lehmann, M. ; Burgy, O. ; Hermann, S. ; Baarsma, H.A. ; Wagner, D.E. ; De Santis, M. ; Ciolek, F. ; Hofer, T.P. ; Frankenberger, M. ; Aichler, M. ; Lindner, M. ; Gesierich, W. ; Guenther, A. ; Walch, A.K. ; Coughlan, C. ; Wolters, P. ; Lee, J.S. ; Behr, J. ; Königshoff, M.
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.Schmitzer, M. ; Winter, H. ; Kneidinger, N. ; Meimarakis, G. ; Dick, A. ; Schramm, R. ; Klotz, L.V. ; Preissler, G. ; Strobl, N. ; von Dossow, V. ; Schneider, C. ; Weig, T. ; Hatz, R. ; Kauke, T.
Persistence of de novo donor-specific HLA-antibodies after lung transplantation: A potential marker of decreased patient survival.Spadaro, M. ; Winklmeier, S. ; Beltrán, E. ; Macrini, C. ; Höftberger, R. ; Schuh, E. ; Thaler, F.S. ; Gerdes, L.A. ; Laurent, S.A. ; Gerhards, R. ; Brändle, S. ; Dornmair, K. ; Breithaupt, C. ; Krumbholz, M. ; Moser, M. ; Kirshnamoorthy, G. ; Kamp, F. ; Jenne, D. ; Hohlfeld, R. ; Kümpfel, T. ; Lassmann, H. ; Kawakami, N. ; Meinl, E.
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.Magkrioti, C. ; Oikonomou, N. ; Kaffe, E. ; Mouratis, M.A. ; Xylourgidis, N. ; Barbayianni, I. ; Megadoukas, P. ; Harokopos, V. ; Valavanis, C. ; Chun, J. ; Kosma, A. ; Stathopoulos, G.T. ; Bouros, E. ; Bouros, D. ; Syrigos, K. ; Aidinis, V.
The autotaxin - lysophosphatidic acid axis promotes lung carcinogenesis.Meiners, S. ; Lloyd, C. ; Chambers, R.C.
Cell–matrix interactions in lung disease and regeneration: ERS lung science conference 2018 report.Heinzelmann, K. ; Lehmann, M. ; Gerckens, M. ; Noskovicova, N. ; Frankenberger, M. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Hilgendorff, A. ; Königshoff, M. ; Eickelberg, O.
Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis.Psallidas, I. ; Kanellakis, N.I. ; Gerry, S. ; Thézénas, M.L. ; Charles, P.D. ; Samsonova, A. ; Schiller, H. B. ; Fischer, R. ; Asciak, R. ; Hallifax, R.J. ; Mercer, R. ; Dobson, M. ; Dong, T. ; Pavord, I.D. ; Collins, G.S. ; Kessler, B.M. ; Pass, H.I. ; Maskell, N. ; Stathopoulos, G.T. ; Rahman, N.M.
Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): A multicohort analysis.Tsai, J.M. ; Weissman, I.L. ; Rinkevich, Y.
Partial lobular hepatectomy: A surgical model for morphologic liver regeneration.Seren, S. ; Rashed Abouzaid, M. ; Eulenberg-Gustavus, C. ; Hirschfeld, J. ; Soliman, H. ; Jerke, U. ; N'Guessan, K. ; Dallet-Choisy, S. ; Lesner, A. ; Lauritzen, C. ; Schacher, B. ; Eickholz, P. ; Nagy, N. ; Széll, M. ; Croix, C. ; Viaud-Massuard, M.C. ; Al Farraj Aldosari, A. ; Ragunatha, S. ; Ibrahim Mostafa, M. ; Giampieri, F. ; Battino, M. ; Cornillier, H. ; Lorette, G. ; Stephan, J.L. ; Goizet, C. ; Pedersen, J. ; Gauthier, F. ; Jenne, D. ; Marchand-Adam, S. ; Chapple, I.L. ; Kettritz, R. ; Korkmaz, B.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.Yang, L. ; Kuang, H. ; Zhang, W. ; Wei, H. ; Xu, H.
Quantum dots cause acute systemic toxicity in lactating rats and growth restriction of offspring.Götzfried, J. ; Smirnova, N.F. ; Morrone, C. ; Korkmaz, B. ; Yildirim, A.Ö. ; Eickelberg, O. ; Jenne, D.
Preservation with alpha(1)-antitrypsin improves primary graft function of murine lung transplants.Kannler, M. ; Lüling, R. ; Yildirim, A.Ö. ; Gudermann, T. ; Steinritz, D. ; Dietrich, A.
TRPA1 channels: Expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia.Meiners, S. ; Evankovich, J. ; Mallampalli, R.K.
The ubiquitin proteasome system as a potential therapeutic target for systemic sclerosis.Reicherzer, T. ; Häffner, S. ; Shahzad, T. ; Gronbach, J. ; Mysliwietz, J. ; Huebener, C. ; Hasbargen, U. ; Gertheiss, J. ; Schulze, A. ; Bellusci, S. ; Morty, R.E. ; Hilgendorff, A. ; Ehrhardt, H.
Activation of the NF-kappa B pathway alters the phenotype of MSCs in the tracheal aspirates of preterm infants with severe BPD.Fritsch-Decker, S. ; Marquardt, C. ; Stöger, T. ; Diabaté, S. ; Weiss, C.
Revisiting the stress paradigm for silica nanoparticles: Decoupling of the anti-oxidative defense, pro-inflammatory response and cytotoxicity.Saxon, J.A. ; Yu, H. ; Polosukhin, V.V. ; Stathopoulos, G.T. ; Gleaves, L.A. ; McLoed, A.G. ; Massion, P.P. ; Yull, F.E. ; Zhao, Z. ; Blackwell, T.S.
P52 expression enhances lung cancer progression.Morrone, C.
Inhibition of neutrophil serine proteases by alpha 1 antitrypsin in during storage preserves primary graft functions of transplanted murine donor lungs.Gradl, R. ; Dierolf, M. ; Guenther, B. ; Hehn, L. ; Möller, W. ; Kutschke, D. ; Yang, L. ; Donnelley, M. ; Murrie, R. ; Erl, A. ; Stöger, T. ; Gleich, B. ; Achterhold, K. ; Schmid, O. ; Pfeiffer, F. ; Morgan, K.S.
In vivo dynamic phase-contrast X-ray Imaging using a compact light source.Zhang, W. ; Ohno, S. ; Steer, B. ; Klee, S. ; Staab-Weijnitz, C.A. ; Wagner, D.E. ; Lehmann, M. ; Stöger, T. ; Königshoff, M. ; Adler, H.
S100a4 is secreted by alternatively activated alveolar macrophages and promotes activation of lung fibroblasts in pulmonary fibrosis.Zhang, P. ; Ding, Z. ; Liu, X. ; Chen, Y. ; Li, J. ; Tao, Z. ; Fei, Y. ; Xue, C. ; Qian, J. ; Wang, X. ; Li, Q. ; Stöger, T. ; Chen, J. ; Bi, Y. ; Yin, R.
Enhanced replication of virulent Newcastle disease virus in chicken macrophages is due to polarized activation of cells by inhibition of TLR7.Vreka, M. ; Lilis, I. ; Papageorgopoulou, M. ; Giotopoulou, G.A. ; Lianou, M. ; Giopanou, I. ; Kanellakis, N.I. ; Spella, M. ; Agalioti, T. ; Armenis, V. ; Goldmann, T. ; Marwitz, S. ; Yull, F.E. ; Blackwell, T.S. ; Pasparakis, M. ; Marazioti, A. ; Stathopoulos, G.T.
IkB kinase a Is required for development and progression of KRAS-mutant lung adenocarcinoma.Knüppel, L. ; Heinzelmann, K. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis.Hartl, D. ; Tirouvanziam, R. ; Laval, J. ; Greene, C.M. ; Habiel, D.M. ; Sharma, L. ; Yildirim, A.Ö. ; Dela Cruz, C.S. ; Hogaboam, C.M.
Innate immunity of the lung: From basic mechanisms to translational medicine.Greiffo, F.R. ; Frankenberger, M. ; Dietel, D. ; Ortega-Gomez, A. ; Behr, J. ; Soehnlein, O. ; Fernandez, I.E. ; Eickelberg, O.
Fractalkine/CX3CR1 axis drives kinetic changes of monocytes in fibrotic Interstitial Lung Disease.Dehmel, S. ; Nathan, P. ; Bartel, S. ; El-Mehrie, N. ; Scherb, H. ; Milger, K. ; John-Schuster, G. ; Yildirim, A.Ö. ; Hyklema, M. ; Irmler, M. ; Beckers, J. ; Schaub, B. ; Eickelberg, O. ; Krauss-Etschmann, S.
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.Jiang, D. ; Correa-Gallegos, D. ; Christ, S. ; Stefanska, A. ; Liu, J. ; Ramesh, P. ; Rajendran, V. ; De Santis, M. ; Wagner, D.E. ; Rinkevich, Y.
Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring.Jia, J. ; Conlon, T.M. ; Sarker, R.S. ; Taşdemir, D. ; Smirnova, N.F. ; Srivastava, B. ; Verleden, S.E. ; Güneş, G. ; Wu, X. ; Prehn, C. ; Gao, J. ; Heinzelmann, K. ; Lintelmann, J. ; Irmler, M. ; Pfeiffer, S. ; Schloter, M. ; Zimmermann, R. ; Hrabě de Angelis, M. ; Beckers, J. ; Adamski, J. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.Guarino, C. ; Gruba, N. ; Grzywa, R. ; Dyguda-Kazimierowicz, E. ; Hamon, Y. ; Łȩgowska, M. ; Skoreński, M. ; Dallet-Choisy, S. ; Marchand-Adam, S. ; Kellenberger, C. ; Jenne, D. ; Sieńczyk, M. ; Lesner, A. ; Gauthier, F. ; Korkmaz, B.
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.Noskovicova, N. ; Heinzelmann, K. ; Burgstaller, G. ; Behr, J. ; Eickelberg, O.
Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation.Houssaini, A. ; Breau, M. ; Kebe, K. ; Abid, S. ; Marcos, E. ; Lipskaia, L. ; Rideau, D. ; Parpaleix, A. ; Huang, J. ; Amsellem, V. ; Vienney, N. ; Validire, P. ; Maitre, B. ; Attwe, A. ; Lukas, C. ; Vindrieux, D. ; Boczkowski, J. ; Derumeaux, G. ; Pende, M. ; Bernard, D. ; Meiners, S. ; Adnot, S.
mTOR pathway activation drives lung cell senescence and emphysema.Shandilya, N. ; Ligthart, T. ; van Voorde, I. ; Stahlmecke, B. ; Clavaguera, S. ; Philippot, C. ; Ding, Y. ; Goede, H.
A nanomaterial release model for waste shredding using a Bayesian belief network.Lai, T. ; Wu, M. ; Liu, J. ; Luo, M.C. ; He, L. ; Wang, X. ; Wu, B.L. ; Ying, S. ; Chen, Z. ; Li, W. ; Shen, H.
Acid-suppressive drug use during pregnancy and the risk of childhood asthma: A meta-analysis.Marazioti, A. ; Lilis, I. ; Vreka, M. ; Apostolopoulou, H. ; Kalogeropoulou, A. ; Giopanou, I. ; Giotopoulou, G.A. ; Krontira, A.C. ; Iliopoulou, M. ; Kanellakis, N.I. ; Agalioti, T. ; Giannou, A.D. ; Jones-Paris, C. ; Iwakura, Y. ; Kardamakis, D. ; Blackwell, T.S. ; Taraviras, S. ; Spella, M. ; Stathopoulos, G.T.
Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.Hellbach, K. ; Meinel, F.G. ; Conlon, T.M. ; Willer, K. ; Yaroshenko, A. ; Velroyen, A. ; Braunagel, M. ; Auweter, S. ; Reiser, M.F. ; Eickelberg, O. ; Pfeiffer, F. ; Yildirim, A.Ö.
X-ray dark-field imaging to depict acute lung inflammation in mice.Rozman, J. ; Rathkolb, B. ; Oestereicher, M.A. ; Schütt, C. ; Ravindranath, A.C. ; Leuchtenberger, S. ; Sharma, S. ; Kistler, M. ; Willershäuser, M. ; Brommage, R. ; Meehan, T.F. ; Mason, J. ; Haselimashhadi, H. ; Hough, T. ; Mallon, A.-M. ; Wells, S. ; Santos, L. ; Lelliott, C.J. ; White, J.K. ; Sorg, T. ; Champy, M.-F. ; Bower, L.R. ; Reynolds, C.L. ; Flenniken, A.M. ; Murray, S.A. ; Nutter, L.M.J. ; Svenson, K.L. ; West, D. ; Tocchini-Valentini, G.P. ; Beaudet, A.L. ; Bosch, F. ; Braun, R.B. ; Dobbie, M.S. ; Gao, X. ; Herault, Y. ; Moshiri, A. ; Moore, B.A. ; Kent Lloyd, K.C. ; McKerlie, C. ; Masuya, H. ; Tanaka, N. ; Flicek, P. ; Parkinson, H.E. ; Sedlacek, R. ; Seong, J.K. ; Wang, C.-K.L. ; Moore, M. ; Brown, S.D. ; Tschöp, M.H. ; Wurst, W. ; Klingenspor, M. ; Wolf, E. ; Beckers, J. ; Machicao, F. ; Peter, A. ; Staiger, H. ; Häring, H.-U. ; Grallert, H. ; Campillos, M. ; Maier, H. ; Fuchs, H. ; Gailus-Durner, V. ; Werner, T. ; Hrabě de Angelis, M. ; IMPC Consortium (Eickelberg, O.) ; IMPC Consortium (Yildirim, A.Ö.)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Burgstaller, G. ; Sengupta, A. ; Vierkotten, S. ; Preissler, G. ; Lindner, M. ; Behr, J. ; Königshoff, M. ; Eickelberg, O.
Distinct niches within the extracellular matrix dictate fibroblast function in (cell free) 3D lung tissue cultures.Maldonado, M. ; Salgado-Aguayo, A. ; Herrera, I. ; Cabrera, S. ; Ortíz-Quintero, B. ; Staab-Weijnitz, C.A. ; Eickelberg, O. ; Ramírez, R. ; Manicone, A.M. ; Selman, M. ; Pardo, A.
Upregulation and nuclear location of MMP28 in alveolar epithelium of idiopathic pulmonary fibrosis.Smirnova, N.F. ; Eickelberg, O.
Epithelial progenitor cells take center stage in lung transplantation.Skronska-Wasek, W. ; Gosens, R. ; Königshoff, M. ; Baarsma, H.A.
WNT receptor signalling in lung physiology and pathology.Zscheppang, K. ; Berg, J.V. ; Hedtrich, S. ; Verheyen, L. ; Wagner, D.E. ; Suttorp, N. ; Hippenstiel, S. ; Hocke, A.C.
Human pulmonary 3D models for translational research.Förster, K. ; Sass, S. ; Ehrhardt, H. ; Mous, D.S. ; Rottier, R.J. ; Oak, P. ; Schulze, A. ; Flemmer, A.W. ; Gronbach, J. ; Hübener, C. ; Desai, T. ; Eickelberg, O. ; Theis, F.J. ; Hilgendorff, A.
Early identification of bronchopulmonary dysplasia using novel biomarkers by proteomic screening.Borry, P. ; Bentzen, H.B. ; Budin-Ljøsne, I. ; Cornel, M.C. ; Howard, H.C. ; Feeney, O. ; Jackson, L. ; Mascalzoni, D. ; Mendes, Á. ; Peterlin, B. ; Riso, B. ; Shabani, M. ; Skirton, H. ; Sterckx, S. ; Vears, D. ; Wjst, M. ; Felzmann, H.
The challenges of the expanded availability of genomic information: An agenda-setting paper.Kostric, M. ; Milger, K. ; Krauss-Etschmann, S. ; Engel, M. ; Vestergaard, G. ; Schloter, M. ; Schöler, A.
Development of a stable lung microbiome in healthy neonatal mice.Leuschner, G. ; Stocker, F. ; Veit, T. ; Kneidinger, N. ; Winter, H. ; Schramm, R. ; Weig, T. ; Matthes, S. ; Ceelen, F. ; Arnold, P. ; Munker, D. ; Klenner, F. ; Hatz, R. ; Frankenberger, M. ; Behr, J. ; Neurohr, C.
Outcome of lung transplantation in idiopathic pulmonary fibrosis with previous anti-fibrotic therapy.Almendros, I. ; Bartel, S. ; Bostantzoglou, C. ; Jubrail, J. ; Lehmann, M. ; Wagner, D.E.
Early career members at the ers lsc 2017: Mechanistic overlap between chronic lung injury and cancer.Maldonado, M. ; Salgado-Aguayo, A. ; Herrera, I. ; Ortiz, B. ; Staab-Weijnitz, C.A. ; Selman, M. ; Pardo, A.
MMP28 is overexpressed in bronchial and alveolar epithelial cells in Idiopathic Pulmonary Fibrosis.Giopanou, I. ; Lilis, I. ; Papadaki, H. ; Papadas, T. ; Stathopoulos, G.T.
A link between ReIB expression and tumor progression in laryngeal cancer.Hellbach, K. ; Yaroshenko, A. ; Willer, K. ; Conlon, T.M. ; Braunagel, M.B. ; Auweter, S. ; Yildirim, A.Ö. ; Eickelberg, O. ; Pfeiffer, F. ; Reiser, M.F. ; Meinel, F.G.
X-ray dark-field radiography facilitates the diagnosis of pulmonary fibrosis in a mouse model.Ding, Y. ; Wohlleben, W. ; Boland, M. ; Vilsmeier, K. ; Riediker, M.
Nano-object release during machining of polymer-based manocomposites depends on process factors and the type of nanofiller.Schmid, O. ; Jud, C. ; Umehara, Y. ; Mueller, D. ; Bucholski, A. ; Gruber, F. ; Denk, O. ; Egle, R. ; Petri-Fink, A. ; Rothen-Rutishauser, B.M.
Biokinetics of aerosolized liposomal ciclosporin A in human lung cells in vitro using an air-liquid cell interface exposure system.Spadaro, M. ; Winklmeier, S. ; Beltran, E. ; Macrini, C. ; Hoeftberger, R. ; Schuh, E. ; Thaler, F.S. ; Gerdes, L.A. ; Laurent, S.A. ; Gerhards, R. ; Braendle, S. ; Dornmair, K. ; Moser, M. ; Krishnamoorthy, G. ; Kamp, F. ; Jenne, D. ; Hohlfeld, R. ; Kmpfel, T. ; Lassmann, H. ; Kawakami, N. ; Meinl, E.
Pathogenic mechanisms of human autoantibodies against myelin oligodendrocyte glycoprotein.Schmid, O. ; Cassee, F.R.
On the pivotal role of dose for particle toxicology and risk assessment: exposure is a poor surrogate for delivered dose.Voigt, C. ; May, P. ; Gottschlich, A. ; Markota, A. ; Wenk, D. ; Gerlach, I. ; Voigt, S. ; Stathopoulos, G.T. ; Arendt, K.A.M. ; Heise, C. ; Rataj, F. ; Janssen, K.P. ; Königshoff, M. ; Winter, H. ; Himsl, I. ; Thasler, W.E. ; Schnurr, M. ; Rothenfußer, S. ; Endres, S. ; Kobold, S.
Cancer cells induce interleukin-22 production from memory CD4+T cells via interleukin-1 to promote tumor growth.Brandsma, C.A. ; de Vries, M. ; Costa, R. ; Woldhuis, R.R. ; Königshoff, M. ; Timens, W.
Lung ageing and COPD: Is there a role for ageing in abnormal tissue repair?Ryerson, C.J. ; Corte, T.J. ; Lee, J.S. ; Richeldi, L. ; Walsh, S.L.F. ; Myers, J.L. ; Behr, J. ; Cottin, V. ; Danoff, S.K. ; Flaherty, K.R. ; Lederer, D.J. ; Lynch, D.A. ; Martinez, F.J. ; Raghu, G. ; Travis, W.D. ; Udwadia, Z. ; Wells, A.U. ; Collard, H.R.
A standardized diagnostic ontology for fibrotic interstitial lung disease. An International Working Group Perspective.Oak, P. ; Hilgendorff, A.
The BPD trio? Interaction of dysregulated PDGF, VEGF, and TGF signaling in neonatal chronic lung disease.Egaña, I. ; Kaito, H. ; Nitzsche, A. ; Becker, L. ; Ballester-Lopez, C. ; Niaudet, C. ; Petkova, M. ; Liu, W. ; Vandlandewijck, M. ; Vernaleken, A. ; Klopstock, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rask-Andersen, H. ; Johansson, H.J. ; Lehtiö, J. ; He, L. ; Yildirim, A.Ö. ; Hellström, M. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Ollert, M. ; Schmidt-Weber, C.B. ; Amarie, O.V. ; Graw, J. ; Beckers, J. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Moreth, K. ; Bekeredjian, R. ; Neff, F. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Rozman, J. ; Klingenspor, M. ; Stöger, T. ; Eickelberg, O. ; Treise, I. ; Busch, D.H. ; Östereicher, M.A. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S.)
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.Tacke, U. ; Weigand-Brunnhölzl, H. ; Hilgendorff, A. ; Giese, R.M. ; Flemmer, A.W. ; König, H. ; Warken-Madelung, B. ; Arens, M. ; Hesse, N. ; Schroeder, A.S.
Entwicklungsneurologie – vernetzte Medizin und neue Perspektiven.Bowl, M.R. ; Simon, M.M. ; Ingham, N.J. ; Greenaway, S. ; Santos, L. ; Cater, H. ; Taylor, S. ; Mason, J. ; Kurbatova, N. ; Pearson, S. ; Bower, L.R. ; Clary, D. ; Meziane, H. ; Reilly, P. ; Minowa, O. ; Kelsey, L. ; Tocchini-Valentini, G.P. ; Gao, X. ; Bradley, A. ; Skarnes, W.C. ; Moore, M. ; Beaudet, A.L. ; Justice, M.J. ; Seavitt, J.R. ; Dickinson, M.E. ; Wurst, W. ; Hrabě de Angelis, M. ; Herault, Y. ; Wakana, S. ; Nutter, L.M.J. ; Flenniken, A.M. ; McKerlie, C. ; Murray, S.A. ; Svenson, K.L. ; Braun, R.E. ; West, D.B. ; Llyod, K.C.K. ; Adams, D.J. ; White, J. ; Karp, N. ; Flicek, P. ; Smedley, D. ; Meehan, T.F. ; Parkinson, H.E. ; Teboul, L. ; Wells, S. ; Steel, K.P. ; Mallon, A.M. ; Brown, S.D. ; International Mouse Phenotyping Consortium (Beig, J. ; Bürger, A. ; Giesert, F. ; Graw, J. ; Kühn, R. ; Oritz, O. ; Schick, J. ; Seisenberger, C. ; Amarie, O.V. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Aguilar-Pimentel, J.A. ; Beckers, J. ; Brommage, R. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Marschall, S. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Treise, I. ; Stöger, T. ; Yildirim, A.Ö. ; Becker, L. ; Rathkolb, B. ; Eickelberg, O. ; Schmidt-Weber, C.B.)
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Mümmler, C. ; Burgy, O. ; Hermann, S. ; Mutze, K. ; Günther, A. ; Königshoff, M.
Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis.Fuchs, H. ; Aguilar-Pimentel, A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Cho, Y.-L. ; Garrett, L. ; Hölter, S.M. ; Irmler, M. ; Kistler, M. ; Kraiger, M. ; Mayer-Kuckuk, P. ; Moreth, K. ; Rathkolb, B. ; Rozman, J. ; da Silva Buttkus, P. ; Treise, I. ; Zimprich, A. ; Gampe, K. ; Hutterer, C. ; Leuchtenberger, S. ; Maier, H. ; Miller, M. ; Scheideler, A. ; Wu, M. ; Beckers, J. ; Bekeredjian, R. ; Brielmeier, M. ; Busch, D.H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Schmidt-Weber, C.B. ; Stöger, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.Schmid, O. ; Stöger, T.
Corrigendum to “Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung” [Journal of Aerosol Science 99 (2016) 133–143](S0021850215301166)(10.1016/j.jaerosci.2015.12.006).Greiffo, F.R. ; Eickelberg, O. ; Fernandez, I.E.
Systems medicine advances in interstitial lung disease.Johnston, B.D. ; Kreyling, W.G. ; Pfeiffer, C. ; Schäffler, M. ; Sarioglu, H. ; Ristig, S. ; Hirn, S. ; Haberl, N. ; Thalhammer, S. ; Hauck, S.M. ; Semmler-Behnke, M. ; Epple, M. ; Hühn, J. ; del Pino, P. ; Parak, W.J.
Colloidal stability and surface chemistry are key factors for the composition of the protein corona of inorganic gold nanoparticles.Bartel, S. ; Jatzlauk, G. ; Kepert, I. ; Fonseca, J. ; Müller, C. ; Milger, K. ; Hochwind, K. ; Kostric, M. ; Eickelberg, O. ; Schloter, M. ; Hartmann, A. ; Schmitt-Kopplin, P. ; Krauss-Etschmann, S.
The metabolite D-tryptophan from probiotic bacteria ameliorates allergic airway disease and influences the gut microbiome.Röhm, M. ; Carle, S. ; Maigler, F. ; Flamm, J. ; Kramer, V. ; Mavoungou, C. ; Schmid, O. ; Schindowski, K.
A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery.Xu, Q. ; Liu, X. ; Wang, X. ; Hua, Y. ; Chen, J. ; Li, J. ; Wang, Y. ; Stöger, T. ; Chen, S. ; Huang, N.
Growth arrest-specific protein 7 regulates the murine M1 alveolar macrophage polarization.Oak, P. ; Pritzke, T. ; Thiel, I. ; Koschlig, M. ; Mous, D.S. ; Windhorst, A. ; Jain, N. ; Eickelberg, O. ; Foerster, K. ; Schulze, A. ; Goepel, W. ; Reicherzer, T. ; Ehrhardt, H. ; Rottier, R.J. ; Ahnert, P. ; Gortner, L. ; Desai, T.J. ; Hilgendorff, A.
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.Segura, M.T. ; Demmelmair, H. ; Krauss-Etschmann, S. ; Nathan, P. ; Dehmel, S. ; Padilla, M.C. ; Rueda, R. ; Koletzko, B. ; Campoy, C.
Maternal BMI and gestational diabetes alter placental lipid transporters and fatty acid composition.Milger, K. ; Yu, Y. ; Brudy, E. ; Irmler, M. ; Skapenko, A. ; Mayinger, M. ; Lehmann, M. ; Beckers, J. ; Reichenberger, F. ; Behr, J. ; Eickelberg, O. ; Königshoff, M. ; Krauss-Etschmann, S.
Pulmonary CCR2+CD4+ T cells are immune regulatory and attenuate lung fibrosis development.Spella, M. ; Marazioti, A. ; Arendt, K.A.M. ; Stathopoulos, G.T.
RAS oncogenes direct metastasis.Lehmann, M. ; Korfei, M. ; Mutze, K. ; Klee, S. ; Skronska-Wasek, W. ; Alsafadi, H.N. ; Ota, C. ; Costa, R. ; Schiller, H. B. ; Lindner, M. ; Wagner, A. ; Günther, A.L. ; Königshoff, M.
Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.Spella, M. ; Lilis, I. ; Stathopoulos, G.T.
Shared epithelial pathways to lung repair and disease.Engel, M. ; Endesfelder, D. ; Schloter-Hai, B. ; Kublik, S. ; Granitsiotis, M.S. ; Boschetto, P. ; Stendardo, M. ; Barta, I. ; Döme, B. ; Deleuze, J.F. ; Boland, A. ; Müller-Quernheim, J. ; Prasse, A. ; Welte, T. ; Hohlfeld, J. ; Subramanian, D. ; Parr, D. ; Gut, I.G. ; Greulich, T. ; Koczulla, A.R. ; Nowinski, A. ; Gorecka, D. ; Singh, D. ; Gupta, S. ; Brightling, C.E. ; Hoffmann, H. ; Frankenberger, M. ; Hofer, T.P. ; Burggraf, D. ; Heiss-Neumann, M.S. ; Ziegler-Heitbrock, L. ; Schloter, M. ; zu Castell, W.
Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome.Gradl, R. ; Dierolf, M. ; Hehn, L. ; Günther, B. ; Yildirim, A.Ö. ; Gleich, B. ; Achterhold, K. ; Pfeiffer, F. ; Morgan, K.S.
Propagation-based phase-contrast x-ray imaging at a compact light source.Burgstaller, G. ; Oehrle, B. ; Gerckens, M. ; White, E.S. ; Schiller, H. B. ; Eickelberg, O.
The instructive extracellular matrix of the lung: Basic composition and alterations in chronic lung disease.Schiller, H. B. ; Mayr, C.H. ; Leuschner, G. ; Strunz, M. ; Staab-Weijnitz, C.A. ; Preisendörfer, S. ; Eckes, B. ; Moinzadeh, P. ; Krieg, T. ; Schwartz, D.A. ; Hatz, R.A. ; Behr, J. ; Mann, M. ; Eickelberg, O.
Deep proteome profiling reveals common prevalence of MZB1-positive plasma B cells in human lung and skin fibrosis.Manfrini, N. ; Ricciardi, S. ; Miluzio, A. ; Fedeli, M. ; Scagliola, A. ; Gallo, S. ; Brina, D. ; Adler, T. ; Busch, D.H. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Biffo, S.
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.Koch, A.
Positive Wirkung inhalativer Kortikoide bei Asthma mit < 2 Symptomtagen.Karp, N.A. ; Mason, J. ; Beaudet, A.L. ; Benjamini, Y. ; Bower, L. ; Braun, R.E. ; Brown, S.D.M. ; Chesler, E.J. ; Dickinson, M.E. ; Flenniken, A.M. ; Fuchs, H. ; Hrabě de Angelis, M. ; Gao, X. ; Guo, S. ; Greenaway, S. ; Heller, R. ; Herault, Y. ; Justice, M.J. ; Kurbatova, N. ; Lelliott, C.J. ; Lloyd, K.C.K. ; Mallon, A.M. ; Mank, J.E. ; Masuya, H. ; McKerlie, C. ; Meehan, T.F. ; Mott, R.F. ; Murray, S.A. ; Parkinson, H. ; Ramirez-Solis, R. ; Santos, L. ; Seavitt, J.R. ; Smedley, D. ; Sorg, T. ; Speak, A.O. ; Steel, K.P. ; Svenson, K.L. ; Wakana, S. ; West, D. ; Wells, S. ; Westerberg, H. ; Yaacoby, S. ; White, J.K. ; International Mouse Phenotyping Consortium (Aguilar-Pimentel, J.A. ; Treise, I. ; Moreth, K. ; Stöger, T. ; Amarie, O.V. ; Neff, C. ; Wurst, W. ; Calzada-Wack, J. ; Marschall, S. ; Brommage, R. ; Steinkamp, R. ; Lengger, C. ; Östereicher, M.A. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Yildirim, A.Ö. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Seisenberger, C. ; Bürger, A. ; Graw, J. ; Eickelberg, O. ; Schmidt-Weber, C.B. ; Gailus-Durner, V. ; Beckers, J. ; Rathkolb, B. ; Rozman, J.) ; Becker, L.
Prevalence of sexual dimorphism in mammalian phenotypic traits.Kaestle, M. ; Bartel, S. ; Geillinger-Kästle, K. ; Irmler, M. ; Beckers, J. ; Ryffel, B. ; Eickelberg, O. ; Krauss-Etschmann, S.
microRNA cluster 106a~363 is involved in T-Helper 17 (Th17) cell differentiation.Ganguly, K. ; Ettehadieh, D. ; Upadhyay, S. ; Takenaka, S. ; Adler, T. ; Karg, E.W. ; Krombach, F. ; Kreyling, W.G. ; Schulz, H. ; Schmid, O. ; Stöger, T.
Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: Comparison of inhalation versus intra-arterial infusion exposures in mice.Tufman, A. ; Kahnert, K. ; Kauffmann-Guerrero, D. ; Manapov, F. ; Milger, K. ; Müller-Lisse, U. ; Winter, H. ; Huber, R.M. ; Schneider, C.
Clinical relevance of the M1b and M1c descriptors from the proposed TNM 8 classification of lung cancer.Hose, A.J. ; Depner, M. ; Illi, S. ; Lau, S. ; Keil, T. ; Wahn, U. ; Fuchs, O. ; Pfefferle, P.I. ; Schmaußer-Hechfellner, E. ; Genuneit, J. ; Lauener, R. ; Karvonen, A.M. ; Roduit, C. ; Dalphin, J.-C. ; Riedler, J. ; Pekkanen, J. ; von Mutius, E. ; Ege, M.J. ; Bauer, C.P. ; Forster, J. ; Zepp, F. ; Wahn, V. ; Schuster, A. ; Bergmann, R.L. ; Bergmann, K.E. ; Reich, A. ; Grabenhenrich, L. ; Schaub, B. ; Loss, G.J. ; Renz, H. ; Kabesch, M. ; Roponen, M. ; Hyvärinen, A. ; Tiittanen, P. ; Remes, S. ; Braun-Fahrländer, C. ; Frei, R. ; Kaulek, V. ; Dalphin, M. ; Doekes, G. ; Blümer, N. ; Frey, U.H.
Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts.Garrett, L. ; Becker, L. ; Rozman, J. ; Puk, O. ; Stöger, T. ; Yildirim, A.Ö. ; Bohla, A. ; Eickelberg, O. ; Hans, W. ; Prehn, C. ; Adamski, J. ; Klopstock, T. ; Rácz, I. ; Zimmer, A. ; Klingenspor, M. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Hrabě de Angelis, M. ; Graw, J. ; Hölter, S.M.
Fgf9Y162C mutation alters information processing and social memory in mice.Αgalioti, T. ; Giannou, A.D. ; Krontira, A.C. ; Kanellakis, N.I. ; Kati, D. ; Vreka, M. ; Pepe, M. ; Spella, M. ; Lilis, I. ; Zazara, D.E. ; Nikolouli, E. ; Spiropoulou, N. ; Papadakis, A. ; Papadia, K. ; Voulgaridis, A. ; Harokopos, V. ; Stamou, P. ; Meiners, S. ; Eickelberg, O. ; Snyder, L.A. ; Antimisiaris, S.G. ; Kardamakis, D. ; Psallidas, I. ; Μarazioti, A. ; Stathopoulos, G.T.
Mutant KRAS promotes malignant pleural effusion formation.Zawada, A.M. ; Zhang, L. ; Emrich, I.E. ; Rogacev, K.S. ; Krezdorn, N. ; Rotter, B. ; Fliser, D. ; Devaux, Y. ; Ziegler-Heitbrock, L. ; Heine, G.H.
Reprint of: MicroRNA profiling of human intermediate monocytes.Milger, K. ; Götschke, J. ; Krause, L. ; Nathan, P. ; Alessandrini, F. ; Tufman, A. ; Fischer, R. ; Bartel, S. ; Theis, F.J. ; Behr, J. ; Dehmel, S. ; Müller, N.S. ; Kneidinger, N. ; Krauss-Etschmann, S.
Identification of a plasma miRNA biomarker-signature for allergic asthma: A translational approach.Greiffo, F.R. ; Fernandez, I.E. ; Frankenberger, M. ; Ortega-Gomez, A. ; Behr, J. ; Soehnlein, O. ; Eickelberg, O.
Monocyte immunophenotyping reflects aberrant activation patterns in interstitial lung disease patients.Heinzelmann, K. ; Noskovicova, N. ; Lehmann, M. ; Lindner, M. ; Hatz, R. ; Behr, J. ; Königshoff, M. ; Eickelberg, O.
Cd82 is a novel mediator of fibroblast proliferation.Fernandez, I.E. ; Roy, R. ; Greiffo, F.R. ; Frankenberger, M. ; Behr, J. ; Forrest, A.R. ; Eickelberg, O.
Quantitative proteomics reveals novel fibrotic networks of myeloid-derived suppressor cell and monocytes in ipf.John-Schuster, G. ; Conlon, T.M. ; Günter, S. ; Eickelberg, O. ; Heikenwalder, M. ; Yildirim, A.Ö.
Lymphotoxin-beta-receptor blockade prevents cigarette smoke-induced COPD.Conlon, T.M. ; Hackl, M. ; Bartel, J. ; Krumsiek, J. ; Irmler, M. ; Beckers, J. ; Theis, F.J. ; Eickelberg, O. ; Yildirim, A.Ö.
2d cross-omics integrated enrichment analysis of human and mice COPD lungs reveal novel pathological mechanisms of disease progression.Conlon, T.M. ; Jia, J. ; Gao, J. ; Heinzelmann, K. ; Tasdemir, D. ; Bayram, H. ; Eickelberg, O. ; Yildirim, A.Ö.
Loss of the cholesterol metabolizing enzyme Ch25h protects against cigarette smoke-induced COPD.Jarosch, I. ; Schneeberger, T. ; Gloeckl, R. ; Kreuter, M. ; Benstz, J. ; Frankenberger, M. ; Neurohr, C. ; Prasse, A. ; Behr, J. ; Kenn, K.
Different effects of pulmonary rehabilitation in Anxious Vs. Non-Anxious patients with idiopathic pulmonary fibrosis - a pilot study.Maldonado, M. ; Ortiz-Quintero, B. ; Herrera, I. ; Ramirez, R. ; Staab-Weijnitz, C.A. ; Eickelberg, O. ; Salgado-Aguayo, A. ; Selman, M. ; Pardo, A.
Matrix metalloproteinase (mmp)-28 is expressed in alveolar epithelial cells in idiopathic pulmonary fibrosis and increases their proliferation and migration.Ciolek, F. ; Heinzelmann, K. ; Eickelberg, O. ; Königshoff, M. ; Baarsma, H.
Regulation and function of non-canonical Wnt-5a in human lung fibroblasts.Welk, V. ; Meul, T. ; Merl-Pham, J. ; Korfei, M. ; Koch, I. ; Semren, N. ; Guenther, A. ; Lindner, M. ; Hauck, S.M. ; Eickelberg, O. ; Meiners, S.
Proteasomal activator 200 (pa200) regulates cellular proliferation: A putative role for Ipf and lung cancer pathogenesis.Ota, C. ; Ng-Blichfeldt, J. ; Mutze, K. ; Baarsma, H. ; Skronska-Wasek, W. ; Königshoff, M.
Hopx-Wnt crosstalk regulates alveolar homeostasis.Bartel, S. ; Schulz, N. ; Alessandrini, F. ; Schamberger, A.C. ; Pagel, P. ; Theis, F.J. ; Milger, K. ; Nößner, E. ; Stick, S.M. ; Kicic, A. ; Eickelberg, O. ; Freishtat, R.J. ; Krauss-Etschmann, S.
Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.Gromann, L.B. ; Scherer, K. ; Yaroshenko, A. ; Bölükbas, D.A. ; Hellbach, K. ; Meinel, F.G. ; Braunagel, M. ; Eickelberg, O. ; Reiser, M.F. ; Pfeiffer, F. ; Meiners, S. ; Herzen, J.
First experiences with in-vivo x-ray dark-field imaging of lung cancer in mice.Kneidinger, N. ; Milger, K. ; Janitza, S. ; Ceelen, F. ; Leuschner, G. ; Dinkel, J. ; Königshoff, M. ; Weig, T. ; Schramm, R. ; Winter, H. ; Behr, J. ; Neurohr, C.
Lung volumes predict survival in patients with chronic lung allograft dysfunction.Giopanou, I. ; Arendt, K.A.M. ; Stathopoulos, G.T.
Lung carcinogenesis and fibrosis taken together: Just coincidence?Lehmann, M. ; Buhl, L. ; Klee, S. ; Wagner, D.E. ; Behr, J. ; Lindner, M. ; Königshoff, M.
Effects of nintedanib and pirfenidone on alveolar epithelial cells in 2d and 3d lung cultures.Hilgendorff, A. ; Pritzke, T. ; Markmann, M. ; Oak, P. ; Koschlig, M. ; Hossain, H. ; Desai, T.
Time dependant effects of mechanical ventilation and hyperoxia on central signalling pathways in the developing lung identified by comprehensive transcriptome analysis.Yin, R. ; Zhang, P. ; Liu, X. ; Chen, Y. ; Tao, Z. ; Ai, L. ; Li, J. ; Yang, Y. ; Li, M. ; Xue, C. ; Qian, J. ; Wang, X. ; Chen, J. ; Li, Y. ; Xiong, Y. ; Zhang, J. ; Stöger, T. ; Bi, Y. ; Ding, Z.
Dispersal and transmission of avian paramyxovirus serotype 4 among wild birds and domestic poultry.Ganguly, K. ; George, L. ; Thimraj, T.A. ; Upadhyay, S. ; Schulz, H. ; Stöger, T.
Skewed alveolar macrophage polarization signature in mice with impaired pulmonary function following carbon nanoparticle exposure.Alsafadi, H.N. ; Lehmann, M. ; Lindner, M. ; Peschel, B. ; Königshoff, M. ; Wagner, D.E.
An ex vivo human model of idiopathic pulmonary fibrosis using precision cut lung slices.Noskovicova, N. ; Heinzelmann, K. ; Burgstaller, G. ; Eickelberg, O.
Cub domain containing protein 1/transforming growth factor-beta 1 cross-talk regulates (myo)fibroblast differentiation.Ng-Blichfeldt, J. ; Ota, C. ; Stolk, J. ; Hiemstra, P. ; Gosens, R. ; Königshoff, M.
Wnt activity marks lung progenitors capable of forming spheres in vitro.Sarker, R.S. ; Conlon, T.M. ; Dorer, J. ; Burgstaller, G. ; Merthan, L. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Bustin, M. ; Furusawa, T. ; Eickelberg, O. ; Yildirim, A.Ö.
Epigenetic histone-1 modulator Hmgn5 regulates cellular apoptosis In COPD pathogenesis.Houssaini, A. ; Breau, M. ; Kebe, K. ; Abid, S. ; Marcos, E. ; Lipskaia, L. ; Rideau, D. ; Parpaleix, A. ; Huang, J. ; Amsellem, V. ; Maitre, B. ; Bizard, E. ; Vienney, N. ; Luka, C. ; Validyre, P. ; Boczkowski, J. ; Derumeaux, G. ; Bernard, D. ; Meiners, S. ; Adnot, S.
Activation of the Mtor pathway drives lung cell senescence and emphysema in chronic obstructive pulmonary disease (COPD).Smirnova, N.F. ; Conlon, T.M. ; Yildirim, A.Ö. ; Eickelberg, O.
Orthotopic lung transplantation in a single- mismatch-based mouse model shows signs of chronic lung allograft dysfunction (clad) associated to inducible bronchus-associated lymphoid tissue (ibalt) formation.Hilgendorff, A. ; Foerster, K. ; Sass, S. ; Stoecklein, S. ; Dietrich, O. ; Pomschar, A. ; Schulze, A. ; Huebener, C. ; Theis, F.J. ; Erhardt, H. ; Flemmer, A.W. ; Ertl-Wagner, B.
Discrimination of pulmonary changes in neonatal chronic lung disease by a new Mri score.Oak, P. ; Pritzke, T. ; Koschlig, M. ; Windhorst, A. ; Jain, N. ; Reicherzer, T. ; Ehrhardt, H. ; Frankenberger, M. ; Schwarz, M.A. ; Hilgendorff, A.
Monocyte-centred inflammatory response driving pulmonary injury in neonatal chronic lung disease.Oak, P. ; Kamgari, N. ; Pritzke, T. ; John-Schuster, G. ; Jia, J. ; Yildirim, A.Ö. ; Hilgendorff, A.
Enhanced vulnerability of the developing lungs by moderate prenatal cigarette smoke upon postnatal injury.Kammerl, I.E. ; Chen, S. ; Vergara, E.E. ; Irmler, M. ; Beckers, J. ; Muchamuel, T. ; Kirk, C. ; Florea, B.I. ; Overkleeft, H.S. ; Eickelberg, O. ; Meiners, S. ; Stöger, T.
Deficiency of immunoproteasome subunits increases alternative polarization of alveolar macrophages.Baarsma, H.A. ; Skronska-Wasek, W. ; Mutze, K. ; Ciolek, F. ; Wagner, D.E. ; John-Schuster, G. ; Heinzelmann, K. ; Guenther, A. ; Bracke, K.R. ; Dagouassat, M. ; Boczkowski, J. ; Brusselle, G.G. ; Smits, R. ; Eickelberg, O. ; Yildirim, A.Ö. ; Königshoff, M.
Non-canonical Wnt-5a signaling impairs endogenous lung repair in COPD.Lopez, C.B. ; Conlon, T.M. ; Ertuez, Z. ; Eickelberg, O. ; Yildirim, A.Ö.
Inflammatory response of lung recruited macrophages is partly regulated by non-canonical notch pathway in chronic obstructive pulmonary diseases (COPD).Schrom, E. ; Huber, M. ; Aneja, M.K. ; Dohmen, C. ; Emrich, D. ; Geiger, J. ; Hasenpusch, G. ; Herrmann-Janson, A. ; Kretzschmann, V. ; Mykhailyk, O. ; Pasewald, T. ; Oak, P. ; Hilgendorff, A. ; Wohlleber, D. ; Hoymann, H. ; Schaudien, D. ; Plank, C. ; Rudolph, C. ; Kubisch-Dohmen, R.
Translation of angiotensin-converting enzyme 2 upon liver- and lung-targeted delivery of optimized chemically modified mRNA.Guarino, C. ; Hamon, Y. ; Croix, C. ; Lamort, A.-S. ; Dallet-Choisy, S. ; Marchand-Adam, S. ; Lesner, A. ; Baranek, T. ; Viaud-Massuard, M.C. ; Lauritzen, C. ; Pedersen, J.H. ; Heuze-Vourc'h, N. ; Si-Tahar, M. ; Firatli, E. ; Jenne, D. ; Gauthier, F. ; Horwitz, M.S. ; Borregaard, N. ; Korkmaz, B.
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.Scherer, K. ; Yaroshenko, A. ; Bölükbas, D.A. ; Gromann, L.B. ; Hellbach, K. ; Meinel, F.G. ; Braunagel, M. ; Berg, J.V. ; Eickelberg, O. ; Reiser, M.F. ; Pfeiffer, F. ; Meiners, S. ; Herzen, J.
X-ray dark-field radiography - in-vivo diagnosis of lung cancer in mice.Giannou, A.D. ; Marazioti, A. ; Kanellakis, N.I. ; Giopanou, I. ; Lilis, I. ; Zazara, D.E. ; Ntaliarda, G. ; Kati, D. ; Armenis, V. ; Giotopoulou, G.A. ; Krontira, A.C. ; Lianou, M. ; Agalioti, T. ; Vreka, M. ; Papageorgopoulou, M. ; Fouzas, S. ; Kardamakis, D. ; Psallidas, I. ; Spella, M. ; Stathopoulos, G.T.
NRAS destines tumor cells to the lungs.Oommen, E. ; Hummel, A.M. ; Allmannsberger, L. ; Cuthbertson, D. ; Carette, S. ; Pagnoux, C. ; Hoffman, G.S. ; Jenne, D. ; Khalidi, N.A. ; Koening, C. ; Langford, C. ; McAlear, C. ; Moreland, L. ; Seo, P. ; Sreih, A. ; Ytterberg, S. ; Merkel, P. ; Specks, U. ; Monach, P.
IgA antibodies to myeloperoxidase in patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss).Gall, H. ; Felix, J.F. ; Schneck, F.K. ; Milger, K. ; Sommer, N. ; Voswinckel, R. ; Franco, O.H. ; Hofman, A. ; Schermuly, R.T. ; Weissmann, N. ; Grimminger, F. ; Seeger, W. ; Ghofrani, H.A.
The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups.Kreyling, W.G. ; Holzwarth, U. ; Haberl, N. ; Kozempel, J. ; Wenk, A. ; Hirn, S. ; Schleh, C. ; Schäffler, M. ; Lipka, J. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics of titanium dioxide nanoparticles after intratracheal instillation in rats (Part 3).Kreyling, W.G. ; Holzwarth, U. ; Schleh, C. ; Kozempel, J. ; Wenk, A. ; Haberl, N. ; Hirn, S. ; Schäffler, M. ; Lipka, J. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics of titanium dioxide nanoparticles after oral application in rats (Part 2).Kreyling, W.G. ; Holzwarth, U. ; Haberl, N. ; Kozempel, J. ; Hirn, S. ; Wenk, A. ; Schleh, C. ; Schäffler, M. ; Lipka, J. ; Semmler-Behnke, M. ; Gibson, N.
Quantitative biokinetics of titanium dioxide nanoparticles after intravenous injection in rats (Part 1).Klar, K. ; Perchermeier, S. ; Bhattacharjee, S. ; Harb, H. ; Adler, T. ; Istvanffy, R. ; Loffredo-Verde, E. ; Oostendorp, R. ; Renz, H. ; Prazeres da Costa, C.U.
Chronic schistosomiasis during pregnancy epigenetically reprograms T cell differentiation in offspring of infected mothers.Tsai, J.M. ; Koh, P.W. ; Stefanska, A. ; Xing, L. ; Walmsley, G.G. ; Poux, N. ; Weissman, I.L. ; Rinkevich, Y.
Localized hepatic lobular regeneration by central-vein-associated lineage-restricted progenitors.Costa, R. ; Königshoff, M.
Linking wnt signaling to mucosal inflammation.Taggart, C. ; Mall, M.A. ; Lalmanach, G. ; Cataldo, D. ; Ludwig, A. ; Janciauskiene, S. ; Heath, N. ; Meiners, S. ; Overall, C.M. ; Schultz, C. ; Turk, B. ; Borensztajn, K.S.
Protean proteases: At the cutting edge of lung diseases.Giopanou, I. ; Lilis, I. ; Papaleonidopoulos, V. ; Agalioti, T. ; Kanellakis, N.I. ; Spiropoulou, N. ; Spella, M. ; Stathopoulos, G.T.
Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis.Papadia, K. ; Markoutsa, E. ; Mourtas, S. ; Giannou, A.D. ; La Ferla, B. ; Nicotra, F. ; Salmona, M. ; Klepetsanis, P. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Multifunctional LUV liposomes decorated for BBB and amyloid targeting. A. In vitro proof-of-concept.Fuchs, O. ; Bahmer, T. ; Rabe, K.F. ; von Mutius, E.
Asthma transition from childhood into adulthood.Geiger, S. ; Hereth, M. ; Forster, D. ; Hollauer, C. ; Ballester, C.F. ; Hermann, E. ; Yildirim, A.Ö. ; Guenther, C.
Amelioration of lung function and pulmonary tissue regeneration after treatment with AAT-expressing human MSCS in a murine model of elastase-induced emphysema.Loerz, C. ; Staab-Weijnitz, C.A. ; Huebbe, P. ; Giller, K. ; Metges, C. ; Rimbach, G. ; Maser, E.
Regulation of 11β-hydroxysteroid dehydrogenase type 1 following caloric restriction and re-feeding is species dependent.Zensen, C. ; Fernandez, I.E. ; Eickelberg, O. ; Feldmann, J. ; Lohmüller, T.
Detecting swelling states of red blood cells by "Cell-fluid coupling spectroscopy".Poobalasingam, T. ; Yates, L.L. ; Walker, S.A. ; Pereira, M. ; Gross, N.Y. ; Ali, A. ; Kolatsi-Joannou, M. ; Jarvelin, M.R. ; Pekkanen, J. ; Papakrivopoulou, E. ; Long, D.A. ; Griffiths, M. ; Wagner, D.E. ; Königshoff, M. ; Hind, M. ; Minelli, C. ; Lloyd, C.M. ; Dean, C.H.
Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.Malik, R. ; Dau, T. ; Gonik, M. ; Sivakumar, A. ; Deredge, D.J. ; Edeleva, E.V. ; Götzfried, J. ; van der Laan, S.W. ; Pasterkamp, G. ; Beaufort, N. ; Seixas, S. ; Bevan, S. ; Lincz, L.F. ; Holliday, E.G. ; Burgess, A.I. ; Rannikmäe, K. ; Minnerup, J. ; Kriebel, J. ; Waldenberger, M. ; Müller-Nurasyid, M. ; Lichtner, P. ; Saleheen, D. ; Rothwell, P.M. ; Levi, C. ; Attia, J. ; Sudlow, C.L. ; Braun, D. ; Markus, H.S. ; Wintrode, P.L. ; Berger, K. ; Jenne, D. ; Dichgans, M.
Common coding variant in SERPINA1 increases the risk for large artery stroke.Vonk, J.M. ; Scholtens, S. ; Postma, D.S. ; Moffatt, M.F. ; Jarvis, D. ; Ramasamy, A. ; Wjst, M. ; Omenaas, E.R. ; Bouzigon, E. ; Demenais, F. ; Nadif, R. ; Siroux, V. ; Polonikov, A.V. ; Solodilova, M. ; Ivanov, V.P. ; Curjuric, I. ; Imboden, M. ; Kumar, A. ; Probst-Hensch, N. ; Ogorodova, L.M. ; Puzyrev, V.P. ; Bragina, E.Y. ; Freidin, M.B. ; Nolte, I.M. ; Farrall, A.M. ; Cookson, W.O.C.M. ; Strachan, D.P. ; Koppelman, G.H. ; Boezen, H.M.
Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.Alsafadi, H.N. ; Staab-Weijnitz, C.A. ; Lehmann, M. ; Lindner, M. ; Peschel, B. ; Königshoff, M. ; Wagner, D.E.
An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.Knüppel, L. ; Ishikawa, Y. ; Aichler, M. ; Heinzelmann, K. ; Hatz, R. ; Behr, J. ; Walch, A.K. ; Bächinger, H.P. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
A novel antifibrotic mechanism of nintedanib and pirfenidone: Inhibition of collagen fibril assembly.Papadia, K. ; Giannou, A.D. ; Markoutsa, E. ; Bigot, C. ; Vanhoute, G. ; Mourtas, S. ; der Linden, A.V. ; Stathopoulos, G.T. ; Antimisiaris, S.G.
Multifunctional LUV liposomes decorated for BBB and amyloid targeting - B. In vivo brain targeting potential in wild-type and APP/PS1 mice.Skronska-Wasek, W. ; Mutze, K. ; Baarsma, H.A. ; Alsafadi, H.N. ; Lehmann, M. ; Costa, R. ; Wagner, D.E. ; Yildirim, A.Ö. ; Königshoff, M.
Reduced frizzled receptor 4 expression prevents WNT/β-catenin-driven alveolar lung repair in COPD.Sattler, C. ; Moritz, F. ; Chen, S. ; Steer, B. ; Kutschke, D. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schmitt-Kopplin, P. ; Adler, H. ; Stöger, T.
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.Altmäe, S. ; Segura, M.T. ; Esteban, F.J. ; Bartel, S. ; Brandi, P. ; Irmler, M. ; Beckers, J. ; Demmelmair, H. ; López-Sabater, C. ; Koletzko, B. ; Krauss-Etschmann, S. ; Campoy, C.
Maternal pre-pregnancy obesity is associated with altered placental transcriptome.Baarsma, H.A. ; Skronska-Wasek, W. ; Mutze, K. ; Ciolek, F. ; Wagner, D.E. ; John-Schuster, G. ; Heinzelmann, K. ; Günther, A. ; Bracke, K.R. ; Dagouassat, M. ; Boczkowski, J. ; Brusselle, G.G. ; Smits, R. ; Eickelberg, O. ; Yildirim, A.Ö. ; Königshoff, M.
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.Zawada, A.M. ; Zhang, L. ; Emrich, I.E. ; Rogacev, K.S. ; Krezdorn, N. ; Rotter, B. ; Fliser, D. ; Devaux, Y. ; Ziegler-Heitbrock, L. ; Heine, G.H.
MicroRNA profiling of human intermediate monocytes.Möller, W. ; Sheng Feng, M.S. ; Domanski, U. ; Franke, K.-J. ; Celik, G. ; Bartenstein, P. ; Becker, S. ; Meyer, G. ; Schmid, O. ; Eickelberg, O. ; Tatkov, S. ; Nilius, G.
Nasal high flow reduces dead space.Storch, U. ; Forst, A. ; Pardatscher, F. ; Erdogmus, S. ; Philipp, M. ; Gregoritza, M. ; Mederos y Schnitzlera, M. ; Gudermann, T.
Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.Hofmann, K. ; Fiedler, S. ; Vierkotten, S. ; Weber, J. ; Klee, S. ; Jia, J. ; Zwickenpflug, W. ; Flockerzi, V. ; Storch, U. ; Yildirim, A.Ö. ; Gudermann, T. ; Königshoff, M. ; Dietrich, A.
Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.Mossina, A. ; Lukas, C. ; Merl-Pham, J. ; Uhl, F.E. ; Mutze, K. ; Schamberger, A.C. ; Staab-Weijnitz, C.A. ; Jia, J. ; Yildirim, A.Ö. ; Königshoff, M. ; Hauck, S.M. ; Eickelberg, O. ; Meiners, S.
Cigarette smoke alters the secretome of lung epithelial cells.Campbell, B. ; Raherison, C. ; Lodge, C.J. ; Lowe, A.J. ; Gislason, T. ; Heinrich, J. ; Sunyer, J. ; Gómez Real, F. ; Norbäck, D. ; Matheson, M.C. ; Wjst, M. ; Dratva, J. ; de Marco, R. ; Jarvis, D. ; Schlünssen, V. ; Janson, C. ; Leynaert, B. ; Svanes, C. ; Dharmage, S.C.
The effects of growing up on a farm on adult lung function and allergic phenotypes: An international population-based study.Kepert, I. ; Fonseca, J. ; Müller, C. ; Milger, K. ; Hochwind, K. ; Kostric, M. ; Fedoseeva, M. ; Ohnmacht, C. ; Dehmel, S. ; Nathan, P. ; Bartel, S. ; Eickelberg, O. ; Schloter, M. ; Hartmann, A. ; Schmitt-Kopplin, P. ; Krauss-Etschmann, S.
D-Tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease.Hilgendorff, A. ; Windhorst, A. ; Klein, M. ; Tchatalbachev, S. ; Windemuth-Kieselbach, C. ; Kreuder, J. ; Heckmann, M. ; Gkatzoflia, A. ; Ehrhardt, H. ; Mysliwietz, J. ; Maier, M. ; Izar, B. ; Billion, A. ; Gortner, L. ; Chakraborty, T. ; Hossain, H.
Gene expression profiling at birth characterizing the preterm infant with early onset infection.Wjst, M. ; Werner, M.
Methods of genotyping.Förster, K. ; Sass, S. ; Dietrich, O. ; Pomschar, A. ; Nährlich, L. ; Schulze, A. ; Flemmer, A.W. ; Ehrhardt, H. ; Hübener, C. ; Eickelberg, O. ; Theis, F.J. ; Ertl-Wagner, B. ; Hilgendorff, A.
LSC Abstract – Early biomarkers indicating the development of neonatal chronic lung disease defined by clinical and imaging parameters.Ge, L. ; Habiel, D.M. ; Hansbro, P.M. ; Kim, R.Y. ; Gharib, S.A. ; Edelman, J.D. ; Königshoff, M. ; Parimon, T. ; Brauer, R. ; Huang, Y. ; Allen, J. ; Jiang, D. ; Kurkciyan, A.A. ; Mizuno, T. ; Stripp, B.R. ; Noble, P.W. ; Hogaboam, C.M. ; Chen, P.
miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways.Kanellakis, N.I. ; Giannou, A.D. ; Pepe, M. ; Agalioti, T. ; Zazara, D.E. ; Vreka, M. ; Lilis, I. ; Giopanou, I. ; Spella, M. ; Marazioti, A. ; Rahman, N. ; Pavord, I.D. ; Psallidas, I. ; Stathopoulos, G.T.
Mouse lung adenocarcinoma cell lines reveal PRL2C2 as a novel lung tumour promoter.Psallidas, I. ; Kanellakis, N.I. ; Vreka, M. ; Giannou, A.D. ; Maniatis, L. ; Moschos, C. ; Giopanou, I. ; Agalioti, T. ; Lilis, I. ; Magkouta, S. ; Kalomenidis, I. ; Rahman, N.M. ; Pavord, I.D. ; Stathopoulos, G.T.
Osteopontin as an airway epithelial tumour promoter.Schnitzler, M.M.Y. ; Storch, U. ; Gudermann, T.
Mechanosensitive G(q/11) protein-coupled receptors mediate myogenic vasoconstriction.Bonella, F. ; Kreuter, M. ; Hagmeyer, L. ; German Nintedanib Compassionate Use Consortium (Neurohr, C. ; Milger, K.) ; Keller, C. ; Kohlhaeufl, M.J. ; Mueller-Quernheim, J. ; Prasse, A.
Insights from the German compassionate use program of nintedanib for the treatment of idiopathic pulmonary fibrosis.Geiger, S. ; Hereth, M. ; Forster, D. ; Hollauer, C. ; Ballester, C.F. ; Hermann, F.G. ; Yildirim, A.Ö. ; Guenther, C.
Amelioration of lung function and pulmonary tissue regeneration after treatment with Alpha-1 antitrypsin (AAT)-expressing mesenchymal stem cells (MSCs) in a murine model of elastase-induced emphysema.Larsson, D.H. ; Vågberg, W. ; Yaroshenko, A. ; Yildirim, A.Ö. ; Hertz, H.M.
High-resolution short-exposure small-animal laboratory x-ray phase-contrast tomography.Dietz, K. ; de los Reyes Jimenez, M. ; Gollwitzer, E.S. ; Chaker, A. ; Zissler, U.M. ; Harris, N.L. ; Königshoff, M. ; Schmidt-Weber, C.B. ; Marsland, B.J. ; Esser-von Bieren, J.
Age-dependent regulation of remodeling factors during allergic airway inflammation.Houssaini, A. ; Abid, S. ; Derumeaux, G. ; Wan, F. ; Parpaleix, A. ; Rideau, D. ; Marcos, E. ; Czibik, G. ; Sawaki, D. ; Dubois-Rande, J.L. ; Zhenlin, L. ; Pende, M. ; Amsellem, V. ; Lipskaia, L. ; Adnot, A.
Selective TSC1 deletion in smooth muscle activates mTOR signaling and induces pulmonary hypertension.Pereira, P.R. ; Oliveira-Junior, M.C. ; MacKenzie, B. ; Chiovatto, J.E.D. ; Matos, Y. ; Greiffo, F.R. ; Rigonato-Oliveira, N.C. ; Brugemman, T.R. ; Delle, H. ; Idzko, M. ; Albertini, R. ; Ligeiro Oliveira, A.P. ; Damaceno-Rodrigues, N.R. ; Caldini, E.G. ; Fernandez, I.E. ; Castro-Faria-Neto, H.C. ; Dolhnikoff, M. ; Eickelberg, O. ; Vieira, R.P.
Exercise reduces lung fibrosis involving serotonin/akt signaling.Hamon, Y. ; Legowska, M. ; Herve, V. ; Dallet-Choisy, S. ; Marchand-Adam, S. ; Vanderlynden, L. ; Demonte, M. ; Williams, R. ; Scott, C.J. ; Si-Tahar, M. ; Heuze-Vourc'h, N. ; Lalmanach, G. ; Jenne, D. ; Lesner, A. ; Gauthier, F. ; Korkmaz, B.
Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases.Korkmaz, B. ; Lesner, A. ; Guarino, C. ; Wysocka, M. ; Kellenberger, C. ; Watier, H. ; Specks, U. ; Gauthier, F. ; Jenne, D.
Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease.Leppkes, M. ; Maueroeder, C. ; Hirth, S. ; Nowecki, S. ; Günther, C. ; Billmeier, U. ; Paulus, S. ; Biermann, M. ; Munoz, L.E. ; Hoffmann, M. ; Wildner, D. ; Croxford, A.L. ; Waisman, A. ; Mowen, K. ; Jenne, D. ; Krenn, V. ; Mayerle, J. ; Lerch, M.M. ; Schett, G. ; Wirtz, S. ; Neurath, M.F. ; Hermann, M. ; Becker, C.
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.White, E.S. ; Borok, Z. ; Brown, K. ; Eickelberg, O. ; Guenther, A. ; Jenkins, R. ; Kolb, M. ; Martinez, F.J. ; Roman, J. ; Sime, P.
An american thoracic society official research statement: Future directions in lung fibrosis research.Strange, C.B. ; Herth, F.J.F. ; Valipour, A. ; Shah, P.L. ; Eberhardt, R. ; Grah, C. ; Egan, J. ; Ficker, J.H. ; Wagner, M. ; Witt, C. ; Liebers, U. ; Hopkins, P.N. ; Gesierich, W. ; Phillips, M.A. ; Stanzel, F. ; McNulty, W. ; Petermann, C. ; Snell, G.I. ; Gompelmann, D.
Step-up randomized controlled trial of segmental vapor ablation in patients with severe emphysema: 6 month results.Oak, P. ; Koschlig, M. ; Windhorst, A. ; Jain, N. ; Reicherzer, T. ; Ehrhardt, H. ; Frankenberger, M. ; Alvira, C.M. ; Schwarz, M.A. ; Eickelberg, O. ; Hilgendorff, A.
Monocyte-centred inflammatory response characterizing early stages of Bpd development in the preterm infant.Jia, J. ; Conlon, T.M. ; Lopez, C.B. ; Eickelberg, O. ; Mall, M.A. ; Yildirim, A.Ö.
Chronic bronchitis enhancement in newborn mice from exposure to environmental tobacco smoke.Bonella, F. ; Kreuter, M. ; Hagmeyer, L. ; Neurohr, C. ; Keller, C. ; Kohlhaeufl, M. ; Mueller-Quernheim, J. ; Milger, K. ; Prasse, A.
Insights from a multi-centre real life experience in Germany with nintedanib for the Tteatment of idiopathic pulmonary fibrosis.Wagner, D.E. ; Mutze, K. ; Schiller, H.B. ; Costa, R. ; Kaminski, N. ; Königshoff, M.
Hippo signaling is deranged in idiopathic pulmonary fibrosis and correlates with disease severity.Knüppel, L. ; Ishikawa, Y. ; Heinzelmann, K. ; Hatz, R. ; Behr, J. ; Bachinger, H. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
Effects of nintedanib and pirfenidone on expression and maturation of collagen - A comprehensive analysis.Behr, J. ; Wirtz, H. ; Prasse, A. ; Pittrow, D. ; Klotsche, J. ; Koschel, D. ; Andreas, S. ; Claussen, M. ; Grohe, C. ; Kreuter, M.
Predictors of mortality in patients with idiopathic pulmonary fibrosis under clinical practice conditions: Insights-Ipf registry.Lehmann, M. ; Mutze, K. ; Schiller, H.B. ; Wagner, D.E. ; Königshoff, M.
Increased alveolar epithelial cell senescence in pulmonary fibrosis.Ciolek, F. ; Königshoff, M. ; Baarsma, H.A.
Regulation of non-canonical Wnt-5a by primary human lung fibroblasts.Skronska-Wasek, W. ; Mutze, K. ; Baarsma, H.A. ; Wagner, D.E. ; Stornaiuolo, M. ; Königshoff, M.
Cigarette smoke-induced downregulation of the epithelial cell enriched WNT receptor Fzd4 contributes to reduced Wnt/beta-catenin signaling and alveolar epithelial cell proliferation in COPD.Keller, I.E. ; Dann, A. ; Lukas, C. ; Brech, D. ; Vosyka, O. ; Nössner, E. ; Eickelberg, O. ; Meiners, S.
Proteasome-dependent Mhc I antigen presentation is altered by cigarette smoke.Conlon, T.M. ; Merthan, L. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Furusawa, T. ; Bustin, M. ; Eickelberg, O. ; Yildirim, A.Ö.
Reduced expression of the epigenetic regulator Hmgn5 enhances susceptibility to emphysema.Baarsma, H.A. ; Skronska-Wasek, W. ; Mutze, K. ; Ciolek, F. ; John-Schuster, G. ; Dagouassat, M. ; Günther, A. ; Boczkowski, J. ; Smits, R. ; Yildirim, A.Ö. ; Königshoff, M.
Non-canonical Wnt-5a compromises endogenous lung repair In COPD.Staab-Weijnitz, C.A. ; Schamberger, A.C. ; Fernandez, I.E. ; Schiller, H. B. ; Heinzelmann, K. ; Sterclova, M. ; Vasakova, M. ; Mann, M. ; Eickelberg, O.
Expression and regulation of glutathione peroxidase 3 in interstitial lung disease.Welk, V. ; Semren, N. ; Korfei, M. ; Günther, A. ; Eickelberg, O.
Proteasome activator 200 (pa200) is dysregulated in fibrotic remodeling of the lung.Koschlig, M. ; Tian, X. ; Sudheendra, D. ; Spiekerkoetter, E.F. ; Hilgendorff, A.
Enhanced effects of hyperoxia on Vessel development in newborn mice heterozygote for the bmp receptor 2.Stelzer, D. ; Ihle, F. ; Weber, A. ; Kneidinger, N. ; Zimmermann, G. ; Ceelen, F. ; Schramm, R. ; Winter, H. ; Frey, L. ; Andraschko, M. ; Vogeser, M. ; Behr, J. ; Neurohr, C.
Impact of posaconazol liquid vs. tablet formulation on plasma trough levels in lung transplant recipients.Wrenn, S. ; Coffey, A. ; Uhl, F.E. ; Bianchi, J. ; Dacken, B. ; Petersen, T. ; Wagner, D.E. ; Boyson, J.E. ; Weiss, D.J.
Decellularized wild type and alpha-galactosyltransferase knockout pig lungs stimulate M2 phenotype in human monocyte/macrophages.Mummler, C. ; Vierkotten, S. ; Mutze, K. ; Günther, A. ; Königshoff, M.
Runt-related transcription factor 2 (runx2) regulates mesenchymal cell differentiation and extracellular matrix production in pulmonary fibrosis.Fernandez, I.E. ; Greiffo, F.R. ; Frankenberger, M. ; Heinzelmann, K. ; Neurohr, C. ; Hatz, R. ; Behr, J. ; Eickelberg, O.
Peripheral blood myeloid-derived suppressor cells reflect disease status In Ipf.Klee, S. ; Lehmann, M. ; Wagner, D.E. ; Baarsma, H.A. ; Königshoff, M.
Wisp1 mediates Il6-dependent proliferation in healthy and Ipf-derived primary human lung fibroblasts.Psallidas, I. ; Kanellakis, N.I. ; Vreka, M. ; Giannou, A.D. ; Maniatis, L. ; Magkouta, S. ; Moschos, C. ; Giopanou, I. ; Agalioti, T. ; Lillis, I. ; Kalomenidis, I. ; Rahman, N.M. ; Stathopoulos, G.T.
Osteopontin as an airway epithelial tumor promoter.Houssaini, A. ; Kebe, K. ; Breau, M. ; Marcos, E. ; Huang, J. ; Attwe, A. ; Bizard, E. ; Abid, S. ; Validire, P. ; Maitre, B. ; Meiners, S. ; Amsellem, V. ; Adnot, S.
Targeting the mtor signaling pathway to inhibit lung cell senescence In chronic obstructive pulmonary disease (COPD).Schmid, O. ; Möller, W. ; Stelzl, A. ; Amarie, O.V. ; Eickelberg, O. ; Yildirim, A.Ö.
Towards standardized airway hyperresponsiveness measurements In mice.Dvorkin-Gheva, A. ; Vanderstocken, G. ; Yildirim, A.Ö. ; Brandsma, C.A. ; Obeidat, M. ; Bossé, Y. ; Hassell, J.A. ; Stampfli, M.R.
Total particulate matter concentration skews cigarette smoke’s gene expression profile.Hilgendorff, A. ; Apitz, C. ; Bonnet, D. ; Hansmann, G.
Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK.Wuttke, S. ; Zimpel, A. ; Bein, T. ; Braig, S. ; Stoiber, K. ; Vollmar, A. ; Müller, D. ; Haastert-Talini, K. ; Schaeske, J. ; Stiesch, M. ; Zahn, G. ; Mohmeyer, A. ; Behrens, P. ; Eickelberg, O. ; Bölükbas, D.A. ; Meiners, S.
Validating metal-organic framework nanoparticles for their nanosafety in diverse biomedical applications.Fuchs, H. ; Sabrautzki, S. ; Przemeck, G.K.H. ; Leuchtenberger, S. ; Lorenz-Depiereux, B. ; Becker, L. ; Rathkolb, B. ; Horsch, M. ; Garrett, L. ; Östereicher, M.A. ; Hans, W. ; Abe, K. ; Sagawa, N. ; Rozman, J. ; Vargas Panesso, I.L. ; Sandholzer, M. ; Lisse, T.S. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Calzada-Wack, J. ; Ehrhard, N. ; Elvert, R. ; Gau, C. ; Hölter, S.M. ; Micklich, K. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Stoeger, C. ; Vernaleken, A. ; Michel, D. ; Diener, S. ; Wieland, T. ; Adamski, J. ; Bekeredjian, R. ; Lengger, C. ; Maier, H. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Strom, T.M. ; Zimmer, A. ; Wolf, E. ; Wurst, W. ; Klopstock, T. ; Beckers, J. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
The first Scube3 mutant mouse line with pleiotropic phenotypic alterations.Dau, T. ; Edeleva, E.V. ; Seidel, S.A. ; Stockley, R.A. ; Braun, D. ; Jenne, D.
Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis.Ota, C. ; Baarsma, H.A. ; Wagner, D.E. ; Hilgendorff, A. ; Königshoff, M.
Linking bronchopulmonary dysplasia to adult chronic lung diseases: Role of WNT signaling.Andrade-Sousa, A.S. ; Rogério Pereira, P. ; MacKenzie, B. ; Oliveira-Junior, M.C. ; Assumpção-Neto, E. ; Brandão-Rangel, M.A. ; Damaceno-Rodrigues, N.R. ; Garcia Caldini, E. ; Velosa, A.P. ; Teodoro, W.R. ; Ligeiro de Oliveira, A.P. ; Dolhnikoff, M. ; Eickelberg, O. ; Vieira, R.P.
Aerobic exercise attenuated bleomycin-induced lung fibrosis in Th2-dominant mice.Liu, X. ; Baarsma, H.A. ; Thiam, C.H. ; Montrone, C. ; Brauner, B. ; Fobo, G. ; Heier, J.S. ; Duscha, S. ; Königshoff, M. ; Angeli, V. ; Ruepp, A. ; Campillos, M.
Systematic identification of pharmacological targets from small-molecule phenotypic screens.Sabrautzki, S. ; Sandholzer, M.A. ; Lorenz-Depiereux, B. ; Brommage, R. ; Przemeck, G.K.H. ; Vargas Panesso, I.L. ; Vernaleken, A. ; Garrett, L. ; Baron, K. ; Yildirim, A.Ö. ; Rozman, J. ; Rathkolb, B. ; Gau, C. ; Hans, W. ; Hölter, S.M. ; Marschall, S. ; Stoeger, C. ; Becker, L. ; Fuchs, H. ; Gailus-Durner, V. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Stefanie, L. ; Wolf, E. ; Strom, T.M. ; Wurst, W. ; Hrabě de Angelis, M.
Viable EdnraY129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.Hellbach, K. ; Yaroshenko, A. ; Willer, K. ; Pritzke, T. ; Baumann, A. ; Hesse, N. ; Auweter, S. ; Reiser, M.F. ; Eickelberg, O. ; Pfeiffer, F. ; Hilgendorff, A. ; Meinel, F.G.
Facilitated diagnosis of pneumothoraces in newborn mice using x-ray dark-field radiography.Fernandez, I.E. ; Greiffo, F.R. ; Frankenberger, M. ; Bandres, J. ; Heinzelmann, K. ; Neurohr, C. ; Hatz, R. ; Hartl, D. ; Behr, J. ; Eickelberg, O.
Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis.Lee, Y.C. ; Idell, S. ; Stathopoulos, G.T.
Translational research in pleural infection and beyond.Steer, B. ; Strehle, M. ; Sattler, C. ; Bund, D. ; Flach, B. ; Stöger, T. ; Haas, J.G. ; Adler, H.
The small noncoding RNAs (sncRNAs) of murine gammaherpesvirus 68 (MHV-68) are involved in regulating the latent-to-lytic switch in vivo.Dietz, K. ; de los Reyes Jimenez, M. ; Gollwitzer, E.S. ; Chaker, A. ; Zissler, U.M. ; Rådmark, O.P. ; Baarsma, H.A. ; Königshoff, M. ; Schmidt-Weber, C.B. ; Marsland, B.J. ; Esser-von Bieren, J.
Age dictates a steroid resistant cascade of Wnt5a, transglutaminase-2 and leukotrienes in inflamed airways.Yu, Y. ; He, Z. ; Cao, Y. ; Tang, H. ; Huang, F.
TAGLN2, a novel regulator involved in Hepatitis B virus transcription and replication.Yin, R. ; Liu, X. ; Zhang, P. ; Chen, Y. ; Xie, G. ; Ai, L. ; Xue, C. ; Qian, J. ; Bi, Y. ; Chen, J. ; Sun, Y. ; Stöger, T. ; Ding, Z.
A Raf kinase inhibitor demonstrates antiviral activities both in vitro and in vivo against different genotypes of virulent Newcastle disease virus.Houssaini, A. ; Kebe, K. ; Breau, M. ; Marcos, E. ; Abid, S. ; Bizard, E. ; Huang, J. ; Attwe, A. ; Rideau, D. ; Validire, P. ; Maitre, B. ; Amsellem, V. ; Meiners, S. ; Adnot, S.
Targeting the mtor signaling pathway to inhibit lung cell senescence in Chronic Obstructive Pulmonary Disease (COPD).Jia, J. ; Conlon, T.M. ; Seimetz, M. ; Bednorz, M. ; Zhou-Suckow, Z. ; Weissmann, N. ; Eickelberg, O. ; Mall, M.A. ; Yildirim, A.Ö.
Cigarette smoke causes acute airways disease and exacerbates chronic obstructive lung disease in neonatal mice.Tufman, A. ; Huber, R.M. ; Voelk, S. ; Aigner, F. ; Edelmann, M. ; Gamarra, F. ; Kiefl, R. ; Kahnert, K. ; Tian, F. ; Boulesteix, A.L. ; Endres, S. ; Kobold, S.
Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases.Weber, A. ; Herr, C. ; Hendrowarsito, L. ; Meyer, N. ; Nennstiel-Ratzel, U. ; von Mutius, E. ; Bolte, G. ; Colon, D. ; Kolb, S.
No further increase in the parent reported prevalence of allergies in Bavarian preschool children: Results from three cross-sectional studies.Smirnova, N.F. ; Schamberger, A.C. ; Nayakanti, S. ; Hatz, R. ; Behr, J. ; Eickelberg, O.
Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs.Schamberger, A.C. ; Schiller, H. B. ; Fernandez, I.E. ; Sterclova, M. ; Heinzelmann, K. ; Hennen, E. ; Hatz, R.A. ; Behr, J. ; Vasakova, M. ; Mann, M. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease.Richter, M.J. ; Milger, K. ; Tello, K. ; Stille, P. ; Seeger, W. ; Mayer, E. ; Ghofrani, H.A. ; Gall, H.
Heart rate response during 6-minute walking testing predicts outcome in operable chronic thromboembolic pulmonary hypertension.Zvarova, B. ; Uhl, F.E. ; Uriarte, J.J. ; Borg, Z.D. ; Coffey, A.L. ; Bonenfant, N.R. ; Weiss, D.J. ; Wagner, D.E.
Residual detergent detection method for nondestructive cytocompatibility evaluation of decellularized whole lung scaffolds.Meiners, S. ; Hilgendorff, A.
Early injury of the neonatal lung contributes to premature lung aging: A hypothesis.de Jong, S.E. ; Selman, M.H.J. ; Adegnika, A.A. ; Amoah, A.S. ; van Riet, E. ; Kruize, Y.C.M. ; Raynes, J.G. ; Rodriguez, A. ; Boakye, D. ; von Mutius, E. ; Knulst, A.C. ; Genuneit, J. ; Cooper, P.J. ; Hokke, C.H. ; Wuhrer, M. ; Yazdanbakhsh, M.
IgG1 Fc N-glycan galactosylation as a biomarker for immune activation.Hector, A. ; Kirn, T. ; Ralhan, A. ; Graepler-Mainka, U. ; Berenbrinker, S. ; Riethmueller, J. ; Hogardt, M. ; Wagner, M. ; Pfleger, A. ; Autenrieth, I. ; Kappler, M. ; Griese, M. ; Eber, E. ; Martus, P. ; Hartl, D.
Microbial colonization and lung function in adolescents with cystic fibrosis.Kammerl, I.E. ; Meiners, S.
Proteasome function shapes innate and adaptive immune responses.Staab-Weijnitz, C.A. ; Eickelberg, O.
Repositioning compounds from cancer drug discovery to IPF: PI3K inhibition.Platz, J. ; Bonenfant, N.R. ; Uhl, F. ; Coffey, A.J. ; McKnight, T. ; Parsons, C. ; Sokocevic, D. ; Borg, Z.D. ; Lam, Y.W. ; Deng, B. ; Fields, J. ; Desarno, M. ; Loi, R. ; Hoffman, A. ; Bianchi, J. ; Dacken, B. ; Petersen, T. ; Wagner, D.E. ; Weiss, D.J.
Comparative study to the use of decellularized alpha-Gal KO pig lungs for xenogeneic lung transplantation.McLoed, A.G. ; Sherrill, T.P. ; Cheng, D.S. ; Han, W. ; Saxon, J.A. ; Gleaves, L.A. ; Wu, P. ; Polosukhin, V.V. ; Karin, M. ; Yull, F.E. ; Stathopoulos, G.T. ; Georgoulias, V. ; Zaynagetdinov, R. ; Blackwell, T.S.
Neutrophil-derived IL-1β impairs the efficacy of NF-κB inhibitors against lung cancer.Chen, S. ; Yin, R. ; Mutze, K. ; Yu, Y. ; Takenaka, S. ; Königshoff, M. ; Stöger, T.
No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice.Psallidas, I. ; Kalomenidis, I. ; Porcel, J.M. ; Robinson, B.W. ; Stathopoulos, G.T.
Malignant pleural effusion: From bench to bedside.Subramanian, D.R. ; Gupta, S. ; Burggraf, D. ; vom Silberberg, S. ; Heimbeck, I. ; Heiss-Neumann, M.S. ; Haeussinger, K. ; Newby, C. ; Hargadon, B. ; Raj, V. ; Singh, D. ; Kolsum, U. ; Hofer, T.P. ; Al-Shair, K. ; Luetzen, N. ; Prasse, A. ; Müller-Quernheim, J. ; Benea, G. ; Leprotti, S. ; Boschetto, P. ; Gorecka, D. ; Nowinski, A. ; Oniszh, K. ; zu Castell, W. ; Hagen, M. ; Barta, I. ; Döme, B. ; Strausz, J. ; Greulich, T. ; Vogelmeier, C. ; Koczulla, A.R. ; Gut, I. ; Hohlfeld, J. ; Welte, T. ; Lavae-Mokhtari, M. ; Ziegler-Heitbrock, L. ; Brightling, C. ; Parr, D.G.
Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography.Zensen, C. ; Buelvas, I. ; Eickelberg, O. ; Lohmueller, T. ; Feldmann, J.
'Optical shaking' of red blood cells: A strategy to measure cell-fluid coupling with optical tweezers.Hamon, Y. ; Legowska, M. ; Herve, V. ; Dallet-Choisy, S. ; Marchand-Adam, S. ; Vanderlynden, L. ; Demonte, M. ; Williams, R. ; Scott, C.J. ; Si-Tahar, M. ; Heuze-Vourc'h, N. ; Lalmanach, G. ; Jenne, D. ; Lesner, A. ; Gauthier, F. ; Korkmaz, B.
Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases.Schmid, O. ; Stöger, T.
Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung.Lowe, A.J. ; Lodge, C.J. ; Allen, K.J. ; Abramson, M.J. ; Matheson, M.C. ; Thomas, P.S. ; Barton, C.A. ; Bennett, C.M. ; Erbas, B. ; Svanes, C. ; Wjst, M. ; Gómez Real, F. ; Perret, J.L. ; Russell, M.A. ; Southey, M.C. ; Hopper, J.L. ; Gurrin, L.C. ; Axelrad, C.J. ; Hill, D.J. ; Dharmage, S.C.
Cohort profile: Melbourne Atopy Cohort study (MACS).Zhou, H. ; Wang, Q. ; Yuan, D. ; Wang, J. ; Huang, Y. ; Wu, H. ; Jian, J. ; Yang, D. ; Huang, N. ; Haisch, C. ; Jiang, Z. ; Chen, S.
Early apoptosis real-time detection by label-free SERS based on externalized phosphatidylserine.Darquenne, C. ; Fleming, J.S. ; Katz, I. ; Martin, A.R. ; Schroeter, J. ; Usmani, O.S. ; Venegas, J. ; Schmid, O.
Bridging the gap between science and clinical efficacy: Physiology, imaging, and modeling of aerosols in the lung.Bowatte, G. ; Lodge, C.J. ; Lowe, A.J. ; Erbas, B. ; Dennekamp, M. ; Marks, G.B. ; Perret, J. ; Hui, J. ; Wjst, M. ; Gurrin, L.C. ; Allen, K.J. ; Abramson, M.J. ; Matheson, M.C. ; Dharmage, S.C.
Do variants in GSTs modify the association between traffic air pollution and asthma in adolescence?Lipka, J. ; Semmler-Behnke, M. ; Wenk, A. ; Burkhardt, J. ; Aigner, A. ; Kreyling, W.G.
Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments.Kolahian, S. ; Fernandez, I.E. ; Eickelberg, O. ; Hartl, D.
Immune mechanisms in pulmonary fibrosis.Welk, V. ; Coux, O. ; Kleene, V. ; Abeza, C. ; Trümbach, D. ; Eickelberg, O. ; Meiners, S.
Inhibition of proteasome activity induces formation of alternative proteasome complexes.Yaroshenko, A. ; Pritzke, T. ; Koschlig, M. ; Kamgari, N. ; Willer, K. ; Gromann, L. ; Auweter, S. ; Hellbach, K. ; Reiser, M. ; Eickelberg, O. ; Pfeiffer, F. ; Hilgendorff, A.
Visualization of neonatal lung injury associated with mechanical ventilation using X-ray dark-field radiography.Ehrhardt, H. ; Pritzke, T. ; Oak, P. ; Kossert, M. ; Biebach, L. ; Forster, K. ; Koschlig, M. ; Alvira, C.M. ; Hilgendorff, A.
Absence of TNF-α enhances inflammatory response in the newborn lung undergoing mechanical ventilation.van Rijt, S.H. ; Bölükbas, D.A. ; Argyo, C. ; Wipplinger, K. ; Naureen, M. ; Datz, S. ; Eickelberg, O. ; Meiners, S. ; Bein, T. ; Schmid, O. ; Stöger, T.
Applicability of avidin protein coated mesoporous silica nanoparticles as drug carriers in the lung.Sui, T. ; Lunt, A.J.G. ; Baimpas, N. ; Sandholzer, M. ; Li, T. ; Zeng, K. ; Landini, G. ; Korsunsky, A.M.
Understanding nature's residual strain engineering at the human dentine-enamel junction interface.Horowitz, J.C. ; Osterholzer, J.J. ; Marazioti, A. ; Stathopoulos, G.T.
"Scar-cinoma": Viewing the fibrotic lung mesenchymal cell in the context of cancer biology.Kermanizadeh, A. ; Gosens, I. ; MacCalman, L. ; Johnston, H. ; Danielsen, P.H. ; Jacobsen, N.R. ; Lenz, A.-G. ; Fernandes, T.F. ; Schins, R.P. ; Cassee, F.R. ; Wallin, H. ; Kreyling, W.G. ; Stöger, T. ; Loft, S. ; Møller, P. ; Tran, L. ; Stone, V.
A multilaboratory toxicological assessment of a panel of 10 engineered nanomaterials to human health - ENPRA project - the highlights, limitations, and current and future challenges.Fernandez, I.E. ; Amarie, O.V. ; Mutze, K. ; Königshoff, M. ; Yildirim, A.Ö. ; Eickelberg, O.
Systematic phenotyping and correlation of biomarkers with lung function and histology in lung fibrosis.Leppkes, M. ; Maueroeder, C. ; Hirth, S. ; Nowecki, S. ; Guenther, C. ; Billmeier, U. ; Paulus, S. ; Biermann, M. ; Munoz, L.E. ; Hoffmann, M. ; Wildner, D. ; Croxford, A.L. ; Waisman, A. ; Mowen, K. ; Jenne, D. ; Krenn, V. ; Mayerle, J. ; Lerch, M.M. ; Schett, G. ; Wirtz, S. ; Neurath, M.F. ; Hermann, M. ; Becker, C.
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.Chen, S. ; Kammerl, I.E. ; Vosyka, O. ; Baumann, T. ; Yu, Y. ; Wu, Y. ; Irmler, M. ; Overkleeft, H.S. ; Beckers, J. ; Eickelberg, O. ; Meiners, S. ; Stöger, T.
Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages.Minelli, C. ; Dean, C.H. ; Hind, M. ; Alves, A.C. ; Amaral, A.F.S. ; Siroux, V. ; Huikari, V. ; Artigas, M.S. ; Evans, D.M ; Loth, D.W. ; Bossé, Y. ; Postma, D.S. ; Sin, D. ; Thompson, J. ; Demenais, F. ; Henderson, J. ; SpiroMeta Consortium () ; CHARGE Consortium (Albrecht, E. ; Flexeder, C. ; Gieger, C. ; Grallert, H. ; Hampel, R. ; Heinrich, J. ; Karrasch, S. ; Schulz, H. ; Wjst, M.) ; Bouzigon, E. ; Jarvis, D. ; Jarvelin, M.R. ; Burney, P.
Association of forced vital capacity with the developmental gene NCOR2.Wysocka, M. ; Gruba, N. ; Grzywa, R. ; Giełdoń, A. ; Bąchor, R. ; Brzozowski, K. ; Sienczyk, M. ; Jenne, D. ; Szewczuk, Z. ; Rolka, K. ; Lesner, A.
PEGylated substrates of NSP4 protease: A tool to study protease specificity.Putman, R.K. ; Hatabu, H. ; Araki, T. ; Gudmundsson, G. ; Gao, W. ; Nishino, M. ; Okajima, Y. ; Dupuis, J. ; Latourelle, J.C. ; Cho, M.H. ; El-Chemaly, S. ; Coxson, H.O. ; Celli, B.R. ; Fernandez, I.E. ; Zazueta, O.E. ; Ross, J.C. ; Harmouche, R. ; Estépar, R.S. ; Diaz, A.A. ; Sigurdsson, S. ; Gudmundsson, E.F. ; Eiriksdottir, G. ; Aspelund, T. ; Budoff, M.J. ; Kinney, G.L. ; Hokanson, J.E. ; Williams, M.C. ; Murchison, J.T. ; MacNee, W. ; Hoffmann, U. ; O'Donnell, C.J. ; Launer, L.J. ; Harrris, T.B. ; Gudnason, V. ; Silverman, E.K. ; O'Connor, G.T. ; Washko, G.R. ; Rosas, I.O. ; Hunninghake, G.M.
Association between interstitial lung abnormalities and all-cause mortality.Klee, S. ; Lehmann, M. ; Wagner, D.E. ; Baarsma, H.A. ; Königshoff, M.
WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.Bartmann, J. ; Frankenberger, M. ; Neurohr, C. ; Eickelberg, O. ; Nößner, E. ; von Wulffen, W.
A novel role of MMP-13 for murine DC function: Its inhibition dampens T cell activation.Heinzelmann, K. ; Noskovicova, N. ; Merl-Pham, J. ; Preissler, G. ; Winter, H. ; Lindner, M. ; Hatz, R.A. ; Hauck, S.M. ; Behr, J. ; Eickelberg, O.
Surface proteome analysis identifies platelet derived growth factor receptor-alpha as a critical mediator of transforming growth factor-beta-induced collagen secretion.Kammerl, I.E. ; Dann, A. ; Mossina, A. ; Brech, D. ; Lukas, C. ; Vosyka, O. ; Nathan, P. ; Conlon, T.M. ; Wagner, D.E. ; Overkleeft, H.S. ; Prasse, A. ; Rosas, I.O. ; Straub, T. ; Krauss-Etschmann, S. ; Königshoff, M. ; Preissler, G. ; Winter, H. ; Lindner, M. ; Hatz, R.A. ; Behr, J. ; Heinzelmann, K. ; Yildirim, A.Ö. ; Nößner, E. ; Eickelberg, O. ; Meiners, S.
Impairment of immunoproteasome function by cigarette smoke and in COPD.Mori, Y. ; Takahashi, N. ; Ogawa, N. ; Gudermann, T.
Oxygen physiology: Sensors and ion channels.Spanjer, A.I. ; Baarsma, H.A. ; Oostenbrink, L.M. ; Jansen, S.R. ; Kuipers, C.C. ; Lindner, M. ; Postma, D.S. ; Meurs, H. ; Heijink, I.H. ; Gosens, R. ; Königshoff, M.
TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8.Lipka, J. ; Semmler-Behnke, M. ; Wenk, A. ; Burkhardt, J. ; Aigner, A. ; Kreyling, W.G.
Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice.Zhang, P. ; Xie, G. ; Liu, X. ; Ai, L. ; Chen, Y. ; Meng, X. ; Bi, Y. ; Chen, J. ; Sun, Y. ; Stöger, T. ; Ding, Z. ; Yin, R.
High genetic diversity of Newcastle disease virus in wild and domestic birds in Northeastern China from 2013 to 2015 reveals potential epidemic trends.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Wu, Y. ; Aichler, M. ; Eickelberg, O. ; Walch, A.K.
Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging.Bardou, O. ; Menou, A. ; François, C. ; Duitman, J.W. ; von der Thüsen, J.H. ; Borie, R. ; Sales, K.U. ; Mutze, K. ; Castier, Y. ; Sage, E.H. ; Liu, L. ; Bugge, T.H. ; Fairlie, D.P. ; Königshoff, M. ; Crestani, B. ; Borensztajn, K.S.
Membrane-anchored serine protease matriptase is a trigger of pulmonary fibrogenesis.Hamon, Y. ; Legowska, M. ; Fergelot, P. ; Dallet-Choisy, S. ; Newell, L. ; Vanderlynden, L. ; Kord Valeshabad, A. ; Acrich, K. ; Kord, H. ; Charalampos, T. ; Morice-Picard, F. ; Surplice, I. ; Zoidakis, J. ; David, K. ; Vlahou, A. ; Ragunatha, S. ; Nagy, N. ; Farkas, K. ; Széll, M. ; Goizet, C. ; Schacher, B. ; Battino, M. ; Al Farraj Aldosari, A. ; Wang, X. ; Liu, Y. ; Marchand-Adam, S. ; Lesner, A. ; Kara, E. ; Korkmaz-Icöz, S. ; Moss, C. ; Eickholz, P. ; Taïeb, A. ; Kavukcu, S. ; Jenne, D. ; Gauthier, F. ; Korkmaz, B.
Analysis of urinary cathepsin C for diagnosing Papillon-Lefèvre syndrome.Conlon, T.M. ; Bartel, J. ; Ballweg, K. ; Günter, S. ; Prehn, C. ; Krumsiek, J. ; Meiners, S. ; Theis, F.J. ; Adamski, J. ; Eickelberg, O. ; Yildirim, A.Ö.
Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema.Chillappagari, S. ; Müller, C. ; Mahavadi, P. ; Guenther, A. ; Nahrlich, L. ; Rosenblum, J. ; Rubin, B.K. ; Henke, M.O.
A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation.Karo-Atar, D. ; Bordowitz, A. ; Wand, O. ; Pasmanik-Chor, M. ; Fernandez, I.E. ; Itan, M. ; Frenkel, R. ; Herbert, D.R. ; Finkelman, F.D. ; Eickelberg, O. ; Munitz, A.
A protective role for IL-13 receptor α 1 in bleomycin-induced pulmonary injury and repair.John-Schuster, G. ; Günter, S. ; Hager, K. ; Conlon, T.M. ; Eickelberg, O. ; Yildirim, A.Ö.
Inflammaging increases susceptibility to cigarette smoke-induced COPD.