Research Group "Allergic Disease Epidemiology"

The research group Allergic Disease Epidemiology aims to investigate environmental and life style factors, genetic markers and metabolic processes for the onset and progression of allergic diseases.

We apply epidemiological statistical modelling techniques to study the complex interplay between environmental and life style factors in combination with metabolic and immunological processes which could be determined or modified by genetic variants in relation to allergic diseases.

The group uses data and biosamples from ongoing birth cohorts (GINIplus and LISA). Further, these data can be combined with information collected during the ongoing KORA-Fit study, allowing for a life-course approach.

The main research goals are:

  • To describe the natural course and trends of prevalence of asthma and allergic diseases (epidemiological life-course approach).

  • To determine the impact of exposures during early childhood and genetic predisposition on the development of the immune system and allergic diseases.

  • To investigate the influence and interplay of lifestyle (e.g. diet, physical activity), environment (e.g. neighborhood and build environment characteristics, greenness and air pollution), genetic and metabolic factors.

  • To evaluate the association of comorbidities such as adiposity and mental health with allergic diseases.