News & Highlights

The German Research Foundation (DFG) has awarded Reinhart Koselleck funding in the amount of 1.25 Mio. Euro to Prof. Irmela Jeremias, head of the Research Unit Apoptosis in Hematopoietic Stem Cells (AHS) at the Stem Cell Center, for her outstanding…

As single-cell omic techniques continue to revolutionize our understanding of gene expression patterns, the need for robust tools to infer gene regulatory networks (GRNs) becomes increasingly urgent. In a new study, Dr. Scialdone and his team at…

Chromosome segregation, a fundamental process in cell division, ensures the precise distribution of genetic material to daughter cells. Chen et al., explore the role of non-coding RNAs contributing to the robustness of this process.

Researchers at the Hamperl lab from the Institute of Epigenetics and Stem Cells (IES), working alongside the Scialdone lab at the institute and Lopes lab in University of Zurich, introduce the innovative approach for accurately mapping the dynamics…

We are happy to announce the date for the 8th Munich Epigenetics Spotlight meeting which will happen on Wednesday, October 23rd, 2024.

Stay tuned for more news!

In a recent publication in Genes and Development, the researchers from Torres-Padilla lab (Institute of Epigenetics and Stem Cells, IES) have shed light on the intricate interplay between nuclear organization and transcriptional activity during early…

On October 16, 2023, the Munich Epigenetics community came together for their 7th annual Epigenetics Spotlight meeting, dedicating an afternoon to explore the latest breakthroughs in the field of epigenetics.

In addition to the enlightening…

We pay tribute to the loss of a remarkable scientist, Colyn Crane-Robinson, who passed away on 5th March 2023. Throughout his lifetime, Colyn's unwavering dedication and infectious enthusiasm enriched our understanding of nucleic acid structures and…

In July, the Torres-Padilla lab published two new manuscripts showcasing their latest research contributions.

The IUBMB Focused Meeting on Integrative Omics of Nuclear Functions co-organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place in Crete (Greece) on October 15-20, 2023.

In a cross-departmental collaboration with the Institute for Diabetes and Cancer (IDC) and the Institute of Virology (Viro), researchers from the Schneider lab (Institute of Functional Epigenetics, IFE) have discovered a novel axis connecting…

The analysis of single-cell RNA-sequencing data is a powerful tool for identifying new types of cells. However, the rarer the cells are, the more challenging it becomes to find and characterize them. This means that rare cells can often go unnoticed,…

The Paris-Munich Epigenetics Workshop & Symposium organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place at the Max Planck Institute of Biochemistry in Munich on June 14-16, 2023.

Before a cell divides, the genomic content of a cell is duplicated during DNA replication. Each cell has many origins of replication (ORIs), but not all are active at the same time, and some fire earlier and some later. Combining their approach to…

Researchers from the Institute for Epigenetics and Stem Cells at Helmholtz Munich studied RNA Polymerase II (Pol II) in early mouse embryos and shed light on transcriptional elongation during zygotic genome activation (ZGA), a key process of…

You are excited about understanding life? You would like to gain hands-on research experience and find out more about the daily life of scientists?

The call for our SUMMER INTERNSHIP PROGRAM 2023 IN EPIGENETICS, STEM CELLS, AND ARTIFICAL…

When a cell divides, the correct distribution of cellular content, such as RNAs, to daughter cells is essential. By tagging RNAs with the new diSpinach aptamer in combination with a self-made microfluidics device, researchers at the Institute of…

Cells must continuously adjust to their environments and cope with changing temperatures, stress conditions, or resources. Particularly, if conditions change repeatedly, it might make sense for cells to adjust more effectively. A collaborative…

The fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.

Inspired by recent work from Antonio Scialdone’s group on the spatial expression of olfactory neurons, Maria Elena Torres Padilla and Robert Schneider, directors of IES and IFE respectively, teamed up with the Deutsches Museum to share our research…

The sixth Munich Epigenetic Spotlight meeting was held at the Stem Cell Center of Helmholtz Munich in Großhadern on Monday 24th October 2022. Keynote speakers were Eileen Furlong from EMBL, Heidelberg, and Yang Shi from the Ludwig Institute for…

The first 'Helmholtz Summer School on Chromatin Biology: A hands-on-expedition', organized by the Institute of Epigenetics and Stem Cells (IES) and the Institute of Functional Epigenetics (IFE) in collaboration with Abcam, took place on Campus from…

Since 2016, the annual Summer Internship Program in Epigenetics, Stem Cells, and Artificial Intelligence gives international students the opportunity to work alongside world-leading scientists on original research. Under the supervision of Kurt…

During her stay in August 2022, Anna Dumitriu ran a workshop with researchers at the Institute for Epigenetics and Stem Cells to share her thoughts and experiences of the creative process underlying her artwork “The Cellular Reprogramming Necklace”.

Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…

Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…

The EU funds a new Innovative Training Network (ITN) in the field of DNA replication, cell fate, and cancer with Helmholtz Munich as a beneficiary. The ITN will investigate the role of DNA replication as a determinant of cell fate and cancer.

The sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose.

Research carried out at Helmholtz Munich has shown that…

From October 17th to 20th October 2022, the conference "EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the Genome" will take place in Granada, Spain. The registration will open soon.

Reversing injury or disease is a major objective in research towards regenerative medicine. Replacing sick or damaged cells with healthy cells in order to repair damaged tissue is one of the most impactful strategies towards that goal. For that, a…

We are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.

The possibility to generate any cell type from a differentiated, somatic cell can advance cell-replacement therapies and holds great promises to regenerative medicine. Therefore, understanding the molecular mechanisms underlying cell-fate changes…

For the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…

After a rigorous peer-review process, the board of trustees of Academia Europeae, the pan-European academy of science, humanities, and letters, has elected our Stem Cell expert Prof. Maria-Elena Torres-Padilla. This is a recognition of her standing…

The work of the Scialdone Lab at the Helmholtz Zentrum München and the Rodriguez at the Imperial College elucidates that differences in mitochondrial activity are key determinants for cellular fitness in various contexts, where endogenous cell…