Study on transplanted hearts reveals risk genes for cardiovascular diseases

Source: Eleonora Adami/MDC

In the largest transcriptome study to date, an international research team including Matthias Heinig (leader of Genetic and Epigenetic Gene Regulation Group at the ICB), have discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions.  They analysed the entire transcriptome of heart tissue in healthy and diseased individuals and the study was recently published in ‘Genome Biology’.

For further information see the original publication: Heinig M et al. (2017): Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy, Genome Biology, and the Helmholtz Zentrum München Press Release