Scientific highlights

20.01.2022

Differential effects of lung inflammation on insulin resistance in humans and mice

The rates of obesity, its associated diseases, and allergies are raising at alarming rates in most countries. House dust mites (HDM) are highly allergenic and exposure often associates with an urban sedentary indoor lifestyle, also resulting in obesity. Researchers investigated the epidemiological association and physiological impact of lung inflammation on obesity and glucose homeostasis. They found that asthma associates with insulin resistance in humans, but HDM challenge results in opposing effects on glucose homeostasis in mice due to increased energy expenditure, reduced adipose inflammation, and hepatosteatosis.

Original article:

Differential effects of lung inflammation on insulin resistance in humans and mice.