Alle Publikationen
Karfusehr, C. ; Eder, M. ; Yang, H.Y. ; Beinsteiner, B. ; Jasnin, M. ; Simmel, F.C.
Self-assembled cell-scale containers made from DNA origami membranes.Urel, H. ; Benassou, S. ; Marti, H. ; Reska, T.T.M. ; Sauerborn, E. ; Pinheiro Alves de Souza, Y. ; Perlas Puente,A. ; Rayo, E. ; Biggel, M. ; Kesselheim, S. ; Borel, N. ; Martin, E.J. ; Venegas, C.B. ; Schloter, M. ; Schröder, K. ; Mittelstrass, J. ; Prospero, S. ; Ferguson, J.M. ; Urban, L.
Nanopore- and AI-empowered microbial viability inference.Introini, V. ; Porcella, G. ; Kidiyoor, G.R. ; Cicuta, P. ; Cosentino Lagomarsino, M.
Quantifying Nuclear Shape Fluctuations During Early Mitosis.Ries, C. ; Stark, T. ; Boulat, B. ; Ruhwedel, T. ; Delling, J.P. ; Infante, A.M. ; von Poblotzki, J.T. ; Ulivi, A.F. ; von Mücke-Heim, I.A. ; Chang, S.C.-E. ; Sakimura, K. ; Itoi, K. ; Nestvogel, D.B. ; Attardo, A. ; Czisch, M. ; Nave, K.A. ; Möbius, W. ; Dimou, L. ; Deussing, J.M.
Neuropeptide CRH prevents premature differentiation of OPCs following CNS injury and in early postnatal development.Gygax, D. ; Ramirez, S. ; Chibesa, M. ; Simpamba, T. ; Riffel, M. ; Riffel, T. ; Srivathsan, A. ; Nijland, R. ; Urban, L.
Evaluation of nanopore sequencing for increasing accessibility of eDNA studies in biodiverse countries.Nappi, A. ; Shilova, L. ; Karaletsos, T. ; Cai, N. ; Casale, F.P.
BayesRVAT enhances rare-variant association testing through Bayesian aggregation of functional annotations.Ma, Q. ; Ma, R. ; Yu, H. ; Jiang, X. ; Zhou, Q. ; Wang, X. ; Liang, X. ; Ni, K.
Inverse design of mode-locked fiber lasers based on conditional generative adversarial network (cGAN).Klassen, M.C. ; Balázs, A. ; Zöllner, J. ; Cleve, N. ; Czichon, L. ; von Schledorn, L. ; Hegermann, J. ; Nawroth, J. ; Roth, D. ; Mielenz, M. ; Hedtfeld, S. ; Stanke, F. ; Rubil, T. ; Ius, F. ; Jonigk, D. ; Hanrahan, J.W. ; Ruhparwar, A. ; Olmer, R. ; Mall, M.A. ; Merkert, S. ; Martin, U.
Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease.Korkmaz, R.Ü. ; Omony, J. ; Tan, X. ; Klotz, M. ; Dragunas, G. ; Chen, S. ; Shankhwar, S. ; Ertüz, Z. ; Müller, C. ; Ragab, M. ; Jeridi, A. ; Augustin, R. ; Nawroth, J. ; Kapellos, T. ; Rankl, B. ; Yildirim, A.Ö. ; von Mutius, E.
The therapeutic potential of farm dust extracts in a mouse model of eosinophilic inflammation.Neckermann, L. ; Erdösi, P. ; Zhang, L. ; Assum, I. ; Dropmann, A. ; Alaoua, S. ; Büttner, M. ; Lin, T. ; Gerstner, M. ; Ebert, M.P. ; Bantel, H. ; Dooley, S. ; Kluth, A. ; Menden, M.P. ; Martinez Jimenez, C.P. ; Hammad, S.
Preclinical evaluation of human ABCB5+ skin-derived stem cells reveals regenerative mechanisms and prognostic markers in a novel ACLF mouse model.Roth, D. ; Zampa, B. ; Augustin, R. ; Payandehjoo, D. ; Porcella, G. ; Sahin, A.T. ; van der Does, A.M. ; Nawroth, J.
Release, transfer, fold: Using a silicone adhesive for on-demand 3D tissue engineering.Matthews, R.E. ; Danac, J.M.C. ; Naden, E.L. ; Farleigh Smith, L.E. ; Lestari, S. ; Gungi, A. ; Appert, A. ; Buttress, T. ; Verma, A. ; Sinclair, O. ; Chong, F. ; Suberu, J. ; Antrobus, R. ; Bonev, B. ; Dawson, M.A. ; Reid, A.J. ; Timms, R.T. ; Ahringer, J. ; Tchasovnikarova, I.A.
CRAMP1 drives linker histone expression to enable Polycomb repression.Schneider, M.R. ; Meier, M.
Bringing high-resolution spatial order to sebaceous glands.Davis, K.A.S. ; Coleman, J.R.I. ; Adams, M. ; Breen, G. ; Cai, N. ; Davies, H.L. ; Davies, K.J.A. ; Dregan, A. ; Eley, T.C. ; Fox, E. ; Holliday, J. ; Hübel, C. ; John, A. ; Kassam, A.S. ; Kempton, M.J. ; Lee, W. ; Li, D. ; Maina, J.G. ; McCabe, R. ; McIntosh, A.M. ; Oram, S. ; Richards, M. ; Skelton, M. ; Starkey, F. ; Ter Kuile, A.R. ; Thornton, L.M. ; Wang, R. ; Yu, Z. ; Zvrskovec, J. ; Hotopf, M.
The UK Biobank mental health enhancement 2022: Methods and results.Ma, R. ; Santino, L.M. ; Chobola, T. ; Armbrust, N. ; Geilenkeuser, J. ; Sukumaran, S. ; Jing, Z. ; Levkina, A. ; Ridderbeek, K. ; Peng, T. ; Truong, D.J.J. ; Doll, S. ; Westmeyer, G.G. ; Cui, J.
A telescopic microscope equipped with a quanta image sensor for live-cell bioluminescence imaging.Merino‐Salomón, A. ; Schneider, J. ; Babl, L. ; Krohn, J.F. ; Sobrinos‐Sanguino, M. ; Schäfer, T. ; Luque-Ortega, J.R. ; Alfonso, C. ; Jimenez, M. ; Jasnin, M. ; Schwille, P. ; Rivas, G.
Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution.Nappi, A. ; Cai, N. ; Casale, F.P.
Bayesian aggregation of multiple annotations enhances rare variant association testing.Spearman, A.L. ; Lin, E.Y. ; Mobley, E.B. ; Chmyrov, A. ; Arus, B.A. ; Turner, D.W. ; Garcia, C.A. ; Bui, K. ; Rowlands, C.J. ; Bruns, O.T. ; Sletten, E.M.
High-resolution multicolor shortwave infrared dynamic in vivo imaging with chromenylium nonamethine dyes.Alvarez-Costes, S. ; Baker, C.S. ; Constantine, R. ; Carroll, E.L. ; Guhlin, J. ; Dutoit, L. ; Ferreira, S. ; Heimeier, D. ; Gemmell, N.J. ; Gillum, J. ; Hamner, R.M. ; Rayment, W. ; Roe, W. ; Te Aikā, B. ; Urban, L. ; Alexander, A.
Leveraging synteny to generate reference genomes for conservation: Assembling the genomes of Hector's and Māui dolphins.Zuber, V. ; Cronjé, T. ; Cai, N. ; Gill, D. ; Bottolo, L.
Bayesian causal graphical model for joint Mendelian randomization analysis of multiple exposures and outcomes.Luo, J. ; Molbay, M. ; Chen, Y. ; Horvath, I. ; Kadletz, K. ; Kick, B. ; Zhao, S. ; Al-Maskari, R. ; Singh, I. ; Ali, M. ; Bhatia, H.S. ; Minde, D.-P. ; Negwer, M. ; Höher, L. ; Calandra, G.M. ; Groschup, B. ; Su, J. ; Kimna, C. ; Rong, Z. ; Galensowske, N. ; Todorov, M.I. ; Jeridi, D. ; Ohn, T.-L. ; Roth, S. ; Simats, A. ; Singh, V. ; Khalin, I. ; Pan, C. ; Arus, B.A. ; Bruns, O.T. ; Zeidler, R. ; Liesz, A. ; Protzer, U. ; Plesnila, N. ; Ussar, S. ; Hellal, F. ; Paetzold, J.C. ; Elsner, M. ; Dietz, H. ; Ertürk, A.
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.Hölzlwimmer, F.R. ; Lindner, J. ; Tsitsiridis, G. ; Wagner, N. ; Casale, F.P. ; Yépez, V.A. ; Gagneur, J.
Aberrant gene expression prediction across human tissues.Zhou, J. ; Ridderbeek, K. ; Zou, P. ; Naden, A.B. ; Gaussmann, S. ; Song, F. ; Falter-Braun, P. ; Kay, E.R. ; Sattler, M. ; Cui, J.
Modular nanoparticle platform for solution-phase optical sensing of protein-protein interactions.Perlas Puente,A. ; Reska, T.T.M. ; Croville, G. ; Tarrés-Freixas, F. ; Guérin, J.L. ; Majó, N. ; Urban, L.
Improvements in RNA and DNA nanopore sequencing allow for rapid genetic characterization of avian influenza.Pieczykolan, M. ; Dancer, P.A. ; Klein, T. ; Piwonski, H. ; Rolbieski, H. ; Maity, B. ; Bruns, O.T. ; Cavallo, L. ; Kiessling, F. ; Rueping, M. ; Banala, S.
Small organic fluorophores with SWIR emission detectable beyond 1300 nm.Han, S. ; Yu, S. ; Shi, M. ; Harada, M. ; Ge, J. ; Lin, J. ; Prehn, C. ; Petrera, A. ; Li, Y. ; Sam, F. ; Matullo, G. ; Adamski, J. ; Suhre, K. ; Gieger, C. ; Hauck, S.M. ; Herder, C. ; Roden, M. ; Casale, F.P. ; Cai, N. ; Peters, A. ; Wang-Sattler, R.
LEOPARD: Missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer.Roth, D. ; Sahin, A.T. ; Ling, F. ; Tepho, N. ; Senger, C.N. ; Quiroz, E.J. ; Calvert, B.A. ; van der Does, A.M. ; Güney, T.G. ; Glasl, S. ; van Schadewijk, A. ; von Schledorn, L. ; Olmer, R. ; Kanso, E. ; Nawroth, J. ; Ryan, A.L.
Structure and function relationships of mucociliary clearance in human and rat airways.Koc-Gunel, S. ; Liu, E.C. ; Gautam, L.K. ; Calvert, B.A. ; Murthy, S. ; Harriott, N.C. ; Nawroth, J. ; Zhou, B. ; Krymskaya, V.P. ; Ryan, A.L.
Targeting fibroblast-endothelial interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics.Cai, N. ; Verhulst, B. ; Andreassen, O.A. ; Buitelaar, J.K. ; Edenberg, H.J. ; Hettema, J.M. ; Gandal, M. ; Grotzinger, A. ; Jonas, K. ; Lee, P. ; Mallard, T.T. ; Mattheisen, M. ; Neale, M.C. ; Nurnberger, J.I. ; Peyrot, W.J. ; Tucker-Drob, E.M. ; Smoller, J.W. ; Kendler, K.S.
Correction: Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.Huang, Y. ; Stankevych, M. ; Gujrati, V. ; Klemm, U. ; Mohammed, A. ; Wiesner, D. ; Saccomano, M. ; Tost, M. ; Feuchtinger, A. ; Mishra, K. ; Bruns, O.T. ; Geerlof, A. ; Ntziachristos, V. ; Stiel, A.-C.
Photoswitching protein-XTEN fusions as injectable optoacoustic probes.Lin, M. ; Zhang, L. ; Wang, Z. ; Liu, H. ; Wang, K. ; Tang, G. ; Wang, W. ; Sun, P.
A combined system with convolutional neural networks and transformers for automated quantification of left ventricular ejection fraction from 2D echocardiographic images.Li, W. ; Li, A. ; Yu, B. ; Zhang, X. ; Liu, X. ; White, K.L. ; Stevens, R.C. ; Baumeister, W. ; Sali, A. ; Jasnin, M. ; Sun, L.
In situ structure of actin remodeling during glucose-stimulated insulin secretion using cryo-electron tomography.Cai, N. ; Verhulst, B. ; Andreassen, O.A. ; Buitelaar, J.K. ; Edenberg, H.J. ; Hettema, J.M. ; Gandal, M. ; Grotzinger, A. ; Jonas, K. ; Lee, P. ; Mallard, T.T. ; Mattheisen, M. ; Neale, M.C. ; Nurnberger, J.I. ; Peyrout, W. ; Tucker-Drob, E.M. ; Smoller, J.W. ; Kendler, K.S.
Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.Bonev, B. ; Castelo-Branco, G. ; Chen, F. ; Codeluppi, S. ; Corces, M.R. ; Fan, J. ; Heiman, M. ; Harris, K. ; Inoue, F. ; Kellis, M. ; Levine, A.P. ; Lotfollahi, M. ; Luo, C. ; Maynard, K.R. ; Nitzan, M. ; Ramani, V. ; Satijia, R. ; Schirmer, L. ; Shen, Y. ; Sun, N. ; Green, G.S. ; Theis, F. ; Wang, X. ; Welch, J.D. ; Gokce, O. ; Konopka, G. ; Liddelow, S.A. ; Macosko, E. ; Ali Bayraktar, O. ; Habib, N. ; Nowakowski, T.J.
Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.Funk, M.C. ; Nawroth, J. ; Lehmann, M.
A breath of the future: A novel human model for COPD and beyond.Sadowski, M. ; Thompson, M. ; Mefford, J. ; Haldar, T. ; Oni-Orisan, A. ; Border, R. ; Pazokitoroudi, A. ; Cai, N. ; Ayroles, J.F. ; Sankararaman, S. ; Dahl, A.W. ; Zaitlen, N.
Characterizing the genetic architecture of drug response using gene-context interaction methods.West, A.G. ; Ayriss, N.J. ; Hoggard, M. ; Digby, A. ; Eason, D. ; Uddstrom, L. ; Chatterton, J. ; Handley, K.M. ; Urban, L. ; Taylor, M.W.
Elusive aetiology of exudative cloacitis in the critically endangered kākāpō.Bonev, B. ; Gonçalo, C.B. ; Chen, F. ; Codeluppi, S. ; Corces, M.R. ; Fan, J. ; Heiman, M. ; Harris, K. ; Inoue, F. ; Kellis, M. ; Levine, A.P. ; Lotfollahi, M. ; Luo, C. ; Maynard, K.R. ; Nitzan, M. ; Ramani, V. ; Satijia, R. ; Schirmer, L. ; Shen, Y. ; Sun, N. ; Green, G.S. ; Theis, F. ; Wang, X. ; Welch, J.D. ; Gokce, O. ; Konopka, G. ; Liddelow, S.A. ; Macosko, E. ; Bayraktar, O. ; Habib, N. ; Nowakowski, T.J.
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.Reverte-López, M. ; Kanwa, N. ; Qutbuddin, Y. ; Belousova, V. ; Jasnin, M. ; Schwille, P.
Self-organized spatial targeting of contractile actomyosin rings for synthetic cell division.Roth, D. ; Sahin, A.T. ; Ling, F. ; Senger, C.N. ; Quiroz, E.J. ; Calvert, B.A. ; van der Does, A.M. ; Güney, T.G. ; Tepho, N. ; Glasl, S. ; van Schadewijk, A. ; von Schledorn, L. ; Olmer, R. ; Kanso, E. ; Nawroth, J. ; Ryan, A.L.
Structure-function relationships of mucociliary clearance in human airways.Dybdahl Krebs, M. ; Georgii Hellberg, K.L. ; Lundberg, M. ; Appadurai, V. ; Ohlsson, H. ; Pedersen, E.S.L. ; Steinbach, J. ; Matthews, J. ; Border, R. ; LaBianca, S. ; Calle, X. ; Meijsen, J.J. ; Ingason, A. ; Buil, A. ; Vilhjálmsson, B.J. ; Flint, J. ; Bacanu, S.A. ; Cai, N. ; Dahl, A. ; Zaitlen, N. ; Werge, T. ; Kendler, K.S. ; Schork, A.J.
Genetic liability estimated from large-scale family data improves genetic prediction, risk score profiling, and gene mapping for major depression.Sens, D.W. ; Shilova, L. ; Gräf, L. ; Grebenshchikova, M. ; Eskofier, B.M. ; Casale, F.P.
Genetics-driven risk predictions leveraging the Mendelian randomization framework.Arteaga Cardona, F. ; Madirov, E. ; Popescu, R. ; Wang, D. ; Busko, D. ; Ectors, D. ; Kübel, C. ; Eggeler, Y.M. ; Arus, B.A. ; Chmyrov, A. ; Bruns, O.T. ; Richards, B.S. ; Hudry, D.
Dramatic impact of materials combinations on the chemical organization of core-shell nanocrystals: Boosting the Tm3+ emission above 1600 nm.Remmert, C. ; Otgonbayar, M. ; Perschel, J.A. ; Marder, M. ; Meier, M.
Protocol to generate a microfluidic vessels-on-chip platform using human pluripotent stem cell-derived endothelial cells.Urban, L. ; Santure, A.W. ; Uddstrom, L.R. ; Digby, A. ; Vercoe, D. ; Eason, D. ; Crane, J. ; Wylie, M.J. ; Davis, T. ; LeLec, M.F. ; Guhlin, J. ; Poulton, S. ; Slate, J. ; Alexander, A. ; Fuentes-Cross, P. ; Dearden, P.K. ; Gemmell, N.J. ; Azeem, F. ; Weyland, M. ; Schwefel, H.G.L. ; van Oosterhout, C. ; Morales, H.E.
The genetic basis of the kākāpō structural color polymorphism suggests balancing selection by an extinct apex predator.Martin, E.J. ; Speak, S.A. ; Urban, L. ; Morales, H.E. ; van Oosterhout, C.
Sonification of genomic data to represent genetic load in Zoo populations.Lamm, L. ; Righetto, R. ; Peng, T.
Mean shift clustering as a loss function for accurate and segmentation-aware localization of macromolecules in cryo-electron tomography.Ortega, J.V. ; Haas, M. ; Effland, A.
Learning Diffusion Functions for Image Restoration.Ling, F. ; Essock-Burns, T. ; McFall-Ngai, M. ; Katija, K. ; Nawroth, J. ; Kanso, E.
Flow physics guides morphology of ciliated organs.Catalán, A. ; Gygax, D. ; Rodríguez-Montes, L. ; Hinzke, T. ; Hoff, K.J. ; Duchen, P.
Two novel genomes of fireflies with different degrees of sexual dimorphism reveal insights into sex-biased gene expression and dosage compensation.Reska, T.T.M. ; Pozdniakova, S. ; Borràs, S. ; Perlas Puente,A. ; Sauerborn, E. ; Cañas, L. ; Schloter, M. ; Rodó, X. ; Wang, Y. ; Winkler, J.B. ; Schnitzler, J.-P. ; Urban, L.
Air monitoring by nanopore sequencing.Esteban, M.E. ; Pino Garcia, D. ; Romero-Lorca, A. ; Novillo, A. ; Gaibar, M. ; Riancho, J.A. ; Rojas-Martinez, A. ; Flores, C. ; Lapunzina, P. ; Carracedo, A. ; Athanasiadis, G.I. ; Fernández-Santander, A.
Worldwide distribution of genetic factors related to severity of COVID-19 infection.Simats, A. ; Zhang, S. ; Messerer, D. ; Chong, F. ; Beşkardeş, S. ; Chivukula, A.S. ; Cao, J. ; Besson-Girard, S. ; Montellano, F.A. ; Morbach, C. ; Carofiglio, O. ; Ricci, A. ; Roth, S. ; Llovera, G. ; Singh, R. ; Chen, Y. ; Filser, S. ; Plesnila, N. ; Braun, C. ; Spitzer, H. ; Gokce, O. ; Dichgans, M. ; Heuschmann, P.U. ; Hatakeyama, K. ; Beltrán, E. ; Clauss, S. ; Bonev, B. ; Schulz, C. ; Liesz, A.
Innate immune memory after brain injury drives inflammatory cardiac dysfunction.Pereira, A. ; Diwakar, S.J. ; Masserdotti, G. ; Beşkardeş, S. ; Simon, T. ; So, Y. ; Martín-Loarte, L. ; Bergemann, F. ; Vasan, L. ; Schauer, T. ; Danese, A. ; Bocchi, R. ; Colomé-Tatché, M. ; Schuurmans, C. ; Philpott, A. ; Straub, T. ; Bonev, B. ; Götz, M.
Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.Sauerborn, E. ; Corredor, N.C. ; Reska, T.T.M. ; Perlas Puente,A. ; Vargas da Fonseca Atum, S. ; Goldman, N. ; Wantia, N. ; Prazeres da Costa, C.U. ; Foster-Nyarko, E. ; Urban, L.
Detection of hidden antibiotic resistance through real-time genomics.Palmer, J.A. ; Rosenthal, N. ; Teichmann, S.A. ; Litvinukova, M.
Revisiting cardiac biology in the rra of single cell and spatial omics.Schneider, J. ; Jasnin, M.
Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography.Wang, F. ; Zhong, Y. ; Bruns, O.T. ; Liang, Y. ; Dai, H.
Author Correction: In vivo NIR-II fluorescence imaging for biology and medicine (Nature Photonics, (2024), 10.1038/s41566-024-01391-5).Yin, K. ; Büttner, M. ; Deligiannis, I.K. ; Strzelecki, M. ; Zhang, L. ; Talavera Lopez, C.N. ; Theis, F.J. ; Odom, D.T. ; Martinez Jimenez, C.P.
Polyploidisation pleiotropically buffers ageing in hepatocytes.Martinez-Sanchez, A. ; Lamm, L. ; Jasnin, M. ; Phelippeau, H.
Simulating the cellular context in synthetic datasets for cryo-electron tomography.Marder, M. ; Remmert, C. ; Perschel, J.A. ; Otgonbayar, M. ; von Toerne, C. ; Hauck, S.M. ; Bushe, J. ; Feuchtinger, A. ; Sheikh, B. ; Moussus, M. ; Meier, M.
Stem cell-derived vessels-on-chip for cardiovascular disease modeling.Brombal, L. ; Arfelli, F. ; Brun, F. ; Di Trapani, V. ; Endrizzi, M. ; Menk, R. ; Perion, P. ; Rigon, L. ; Saccomano, M. ; Tromba, G. ; Olivo, A.
Edge-illumination spectral phase-contrast tomography.Wang, F. ; Zhong, Y. ; Bruns, O.T. ; Liang, Y. ; Dai, H.
In vivo NIR-II fluorescence imaging for biology and medicine.Schmidt, S. ; Li, W. ; Schubert, M. ; Binnewerg, B. ; Prönnecke, C. ; Zitzmann, F.D. ; Bulst, M. ; Wegner, S. ; Meier, M. ; Guan, K. ; Jahnke, H.G.
Novel high-dense microelectrode array based multimodal bioelectronic monitoring system for cardiac arrhythmia re-entry analysis.Meng, X. ; Navoly, G. ; Giannakopoulou, O. ; Levey, D.F. ; Koller, D. ; Pathak, G.A. ; Koen, N. ; Lin, K. ; Adams, M.J. ; Rentería, M.E. ; Feng, Y. ; Gaziano, J.M. ; Stein, D.J. ; Zar, H.J. ; Campbell, M.L. ; van Heel, D.A. ; Trivedi, B. ; Finer, S. ; McQuillin, A. ; Bass, N.J. ; Chundru, V.K. ; Martin, H.C. ; Huang, Q.Q. ; Valkovskaya, M. ; Chu, C.Y. ; Kanjira, S. ; Kuo, P.H. ; Chen, H.C. ; Tsai, S.J. ; Liu, Y.L. ; Kendler, K.S. ; Peterson, R.E. ; Cai, N. ; Fang, Y.J. ; Sen, S. ; Scott, L.J. ; Burmeister, M. ; Loos, R.J.F. ; Preuss, M.H. ; Actkins, K.V. ; Davis, L.K. ; Uddin, M.N. ; Wani, A.H. ; Wildman, D.E. ; Aiello, A.E. ; Ursano, R.J. ; Kessler, R.C. ; Kanai, M. ; Okada, Y. ; Sakaue, S. ; Rabinowitz, J.A. ; Maher, B.S. ; Uhl, G. ; Eaton, W. ; Cruz-Fuentes, C.S. ; Martinez-Levy, G.A. ; Campos, A.I. ; Millwood, I.Y. ; Chen, Z. ; Li, L. ; Wassertheil-Smoller, S. ; Jiang, Y. ; Tian, C. ; Martin, N.G. ; Mitchell, B.L. ; Byrne, E.M. ; Awasthi, S. ; Coleman, J.R.I. ; Ripke, S. ; Sofer, T. ; Walters, R.G. ; McIntosh, A.M. ; Polimanti, R. ; Dunn, E.C. ; Stein, M.B. ; Gelernter, J. ; Lewis, C.M. ; Kuchenbaecker, K.
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.Pfaller, A.M. ; Kaplan, L. ; Moreira Carido Pereira, M. ; Grassmann, F. ; Díaz-Lezama, N. ; Ghaseminejad, F. ; Wunderlich, K.A. ; Glänzer, S. ; Bludau, O. ; Pannicke, T. ; Weber, B.H.F. ; Koch, S.F. ; Bonev, B. ; Hauck, S.M. ; Grosche, A.
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice.Zitzmann, F.D. ; Schmidt, S. ; Frank, R. ; Weigel, W. ; Meier, M. ; Jahnke, H.G.
Microcavity well-plate for automated parallel bioelectronic analysis of 3D cell cultures.Wagner, S. ; Matek, C. ; Shetab Boushehri, S. ; Boxberg, M. ; Lamm, L. ; Sadafi, A. ; Winter, D. ; Marr, C. ; Peng, T.
Built to last? Reproducibility and reusability of deep learning algorithms in computational pathology.Urban, L. ; Miller, A.K. ; Eason, D. ; Vercoe, D. ; Shaffer, M. ; Wilkinson, S.P. ; Jeunen, G.J. ; Gemmell, N.J. ; Digby, A.
Non-invasive real-time genomic monitoring of the critically endangered kākāpō.Huang, L. ; Tang, S. ; Rietkerk, J. ; Appadurai, V. ; Krebs, M.D. ; Schork, A.J. ; Werge, T. ; Zuber, V. ; Kendler, K. ; Cai, N.
Polygenic analyses show important differences between MDD symptoms collected using PHQ9 and CIDI-SF.Noack, F. ; Vangelisti, S. ; Ditzer, N. ; Chong, F. ; Albert, M. ; Bonev, B.
Joint epigenome profiling reveals cell-type-specific gene regulatory programmes in human cortical organoids.Hörner, M. ; Becker, J. ; Bohnert, R. ; Baños, M. ; Jerez-Longres, C. ; Mühlhäuser, V. ; Härrer, D. ; Wong, T.W. ; Meier, M. ; Weber, W.
A photoreceptor-based hydrogel with red light-responsive reversible sol-gel transition as transient cellular matrix.Adams, C.I.M. ; Jeunen, G.J. ; Cross, H. ; Taylor, H.R. ; Bagnaro, A. ; Currie, K. ; Hepburn, C. ; Gemmell, N.J. ; Urban, L. ; Baltar, F. ; Stat, M. ; Bunce, M. ; Knapp, M.
Environmental DNA metabarcoding describes biodiversity across marine gradients.Lingg, J.G.P. ; Bischof, T.S. ; Arus, B.A. ; Cosco, E. ; Sletten, E.M. ; Rowlands, C.J. ; Bruns, O.T. ; Chmyrov, A.
Shortwave-infrared line-scan confocal microscope for deep tissue imaging in intact organs.Rädsch, T. ; Reinke, A. ; Weru, V. ; Tizabi, M.D. ; Schreck, N. ; Kavur, A.E. ; Pekdemir, B. ; Roß, T. ; Kopp-Schneider, A. ; Maier-Hein, L.
Labelling instructions matter in biomedical image analysis.Nawroth, J. ; Giez, C. ; Klimovich, A. ; Kanso, E. ; Bosch, T.C.G.
Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host-microbe associations.Sánchez Quant, E.S. ; Richter, M. ; Colomé-Tatché, M. ; Martinez Jimenez, C.P.
Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge.Gruber, T. ; Contreras, R. ; Sánchez Quant, E.S. ; Miok, V. ; Makris, K. ; Le Thuc, O. ; Gonzales García, I. ; Garcia-Clavé, E. ; Althammer, F. ; Krabichler, Q. ; DeCamp, L.M. ; Jones, R.G. ; Lutter, D. ; Williams, R.H. ; Pfluger, P.T. ; Müller, T.D. ; Woods, S.C. ; Pospisilik, J.A. ; Martinez-Jimenez, C.P. ; Tschöp, M.H. ; Grinevich, V. ; García-Cáceres, C.
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.An, U. ; Pazokitoroudi, A. ; Alvarez, M. ; Huang, L. ; Bacanu, S.A. ; Schork, A.J. ; Kendler, K. ; Pajukanta, P. ; Flint, J. ; Zaitlen, N. ; Cai, N. ; Dahl, A. ; Sankararaman, S.
Deep learning-based phenotype imputation on population-scale biobank data increases genetic discoveries.Dahl, A. ; Thompson, M.L. ; An, U. ; Krebs, M.D. ; Appadurai, V. ; Border, R. ; Bacanu, S.A. ; Werge, T. ; Flint, J. ; Schork, A.J. ; Sankararaman, S. ; Kendler, K.S. ; Cai, N.
Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder.West, A.G. ; Digby, A. ; Santure, A.W. ; Guhlin, J.G. ; Dearden, P. ; Taylor, M.W. ; Urban, L.
Capturing species-wide diversity of the gut microbiota and its relationship with genomic variation in the critically endangered kākāpō.Rosowski, S. ; Remmert, C. ; Marder, M. ; Akishiba, M. ; Bushe, J. ; Feuchtinger, A. ; Platen, A. ; Ussar, S. ; Theis, F.J. ; Wiedenmann, S. ; Meier, M.
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.Carvajal Maldonado, J. ; Lamm, L. ; Liu, Y. ; Righetto, R. ; Schnabel, J.A. ; Peng, T.
F2FD: Fourier Perturbations for Denoising Cryo-Electron Tomograms and Comparison to Established Approaches.Barbosa, I.A.M. ; Gopalakrishnan, R. ; Mercan, S. ; Mourikis, T.P. ; Martin, T. ; Wengert, S. ; Sheng, C. ; Ji, F. ; Lopes, R. ; Knehr, J. ; Altorfer, M. ; Lindeman, A. ; Russ, C. ; Naumann, U. ; Golji, J. ; Sprouffske, K. ; Barys, L. ; Tordella, L. ; Schübeler, D. ; Schmelzle, T. ; Galli, G.G.
Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens.Urban, L. ; Perlas Puente,A. ; Francino, O. ; Martí-Carreras, J. ; Muga, B.A. ; Mwangi, J.W. ; Boykin Okalebo, L. ; Stanton, J.A.L. ; Black, A. ; Waipara, N. ; Fontsere, C. ; Eccles, D. ; Urel, H. ; Reska, T.T.M. ; Morales, H.E. ; Palmada-Flores, M. ; Marques-Bonet, T. ; Watsa, M. ; Libke, Z. ; Erkenswick, G. ; van Oosterhout, C.
Real-time genomics for One Health.Merz, S. ; Breunig, M. ; Melzer, M.K. ; Heller, S. ; Wiedenmann, S. ; Seufferlein, T. ; Meier, M. ; Krüger, J. ; Mulaw, M.A. ; Hohwieler, M. ; Kleger, A.
Single-cell profiling of GP2-enriched pancreatic progenitors to simultaneously create acinar, ductal, and endocrine organoids.Wirth, J. ; Huber, N. ; Yin, K. ; Brood, S. ; Chang, S.C.-E. ; Martinez Jimenez, C.P. ; Meier, M.
Spatial transcriptomics using multiplexed deterministic barcoding in tissue.Theissinger, K. ; Fernandes, C. ; Formenti, G. ; Bista, I. ; Berg, P.R. ; Bleidorn, C. ; Bombarely, A. ; Crottini, A. ; Gallo, G.R. ; Godoy, J.A. ; Jentoft, S. ; Malukiewicz, J. ; Mouton, A. ; Oomen, R.A. ; Paez, S. ; Palsbøll, P.J. ; Pampoulie, C. ; Ruiz-López, M.J. ; Secomandi, S. ; Svardal, H. ; Theofanopoulou, C. ; de Vries, J. ; Waldvogel, A.M. ; Zhang, G. ; Jarvis, E.D. ; Bálint, M. ; Ciofi, C. ; Waterhouse, R.M. ; Mazzoni, C.J. ; Höglund, J. ; European Reference Genome Atlas Consortium (Urban, L.)
How genomics can help biodiversity conservation.Moore, J.L. ; Bhaskar, D. ; Gao, F. ; Matte-Martone, C. ; Du, S. ; Lathrop, E. ; Ganesan, S. ; Shao, L. ; Norris, R. ; Campamà Sanz, N. ; Annusver, K. ; Kasper, M. ; Cox, A. ; Hendry, C. ; Rieck, B. ; Krishnaswamy, S. ; Greco, V.
Cell cycle controls long-range calcium signaling in the regenerating epidermis.Klein, T. ; Yang, S. ; Tusty, M.A. ; Nayak, J.V. ; Chang, M.T. ; Bruns, O.T. ; Bischof, T.S. ; Valdez, T.A.
Development of a shortwave infrared sinuscope for the detection of cerebrospinal fluid leaks.von Schledorn, L. ; Puertollano Martín, D. ; Cleve, N. ; Zöllner, J. ; Roth, D. ; Staar, B.O. ; Hegermann, J. ; Ringshausen, F.C. ; Nawroth, J. ; Martin, U. ; Olmer, R.
Primary ciliary dyskinesia patient-specific hiPSC-derived airway epithelium in air-liquid interface culture recapitulates disease specific phenotypes in vitro.Arus, B.A. ; Cosco, E. ; Yiu, J. ; Balba, I. ; Bischof, T.S. ; Sletten, E.M. ; Bruns, O.T.
Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice.Fürtjes, G. ; Reinecke, D. ; von Spreckelsen, N. ; Meißner, A.K. ; Rueß, D. ; Timmer, M. ; Freudiger, C. ; Ion-Margineanu, A. ; Khalid, F. ; Watrinet, K. ; Mawrin, C. ; Chmyrov, A. ; Goldbrunner, R. ; Bruns, O.T. ; Neuschmelting, V.
Intraoperative microscopic autofluorescence detection and characterization in brain tumors using stimulated Raman histology and two-photon fluorescence.Guhlin, J. ; Le Lec, M.F. ; Wold, J. ; Koot, E. ; Winter, D. ; Biggs, P.J. ; Galla, S.J. ; Urban, L. ; Foster, Y. ; Cox, M.P. ; Digby, A. ; Uddstrom, L.R. ; Eason, D. ; Vercoe, D. ; Davis, T. ; Howard, J.T. ; Jarvis, E.D. ; Robertson, F.E. ; Robertson, B.C. ; Gemmell, N.J. ; Steeves, T.E. ; Santure, A.W. ; Dearden, P.K.
Species-wide genomics of kākāpō provides tools to accelerate recovery.Kolabas, Z.I. ; Kuemmerle, L. ; Perneczky, R. ; Förstera, B. ; Ulukaya, S. ; Ali, M. ; Kapoor, S. ; Bartos, L.M. ; Büttner, M. ; Caliskan, Ö.S. ; Rong, Z. ; Mai, H. ; Höher, L. ; Jeridi, D. ; Molbay, M. ; Khalin, I. ; Deligiannis, I.K. ; Negwer, M. ; Roberts, K. ; Simats, A. ; Carofiglio, O. ; Todorov, M.I. ; Horvath, I. ; Öztürk, F. ; Hummel, S. ; Biechele, G. ; Zatcepin, A. ; Unterrainer, M. ; Gnörich, J. ; Roodselaar, J. ; Shrouder, J. ; Khosravani, P. ; Tast, B. ; Richter, L. ; Díaz-Marugán, L. ; Kaltenecker, D. ; Lux, L. ; Chen, Y. ; Zhao, S. ; Rauchmann, B.S. ; Sterr, M. ; Kunze, I. ; Stanic Aguilera, K.N. ; Kan, V.W.Y. ; Besson-Girard, S. ; Katzdobler, S. ; Palleis, C. ; Schädler, J. ; Paetzold, J.C. ; Liebscher, S. ; Hauser, A.E. ; Gokce, O. ; Lickert, H. ; Steinke, H. ; Benakis, C. ; Braun, C. ; Martinez Jimenez, C.P. ; Buerger, K. ; Albert, N.L. ; Höglinger, G. ; Levin, J. ; Haass, C. ; Kopczak, A. ; Dichgans, M. ; Havla, J. ; Kümpfel, T. ; Kerschensteiner, M. ; Schifferer, M. ; Simons, M. ; Liesz, A. ; Krahmer, N. ; Bayraktar, O.A. ; Franzmeier, N. ; Plesnila, N. ; Erener, S. ; Puelles, V.G. ; Delbridge, C. ; Bhatia, H.S. ; Hellal, F. ; Elsner, M. ; Bechmann, I. ; Ondruschka, B. ; Brendel, M. ; Theis, F.J. ; Ertürk, A.
Distinct molecular profiles of skull bone marrow in health and neurological disorders.Atwell, S. ; Waibel, D.J.E. ; Shetab Boushehri, S. ; Wiedenmann, S. ; Marr, C. ; Meier, M.
Label-free imaging of 3D pluripotent stem cell differentiation dynamics on chip.McCaw, Z.R. ; O'Dushlaine, C. ; Somineni, H. ; Bereket, M. ; Klein, C. ; Karaletsos, T. ; Casale, F.P. ; Koller, D. ; Soare, T.W.
An allelic-series rare-variant association test for candidate-gene discovery.Arteaga Cardona, F. ; Jain, N. ; Popescu, R. ; Busko, D. ; Madirov, E. ; Arus, B.A. ; Gerthsen, D. ; De Backer, A. ; Bals, S. ; Bruns, O.T. ; Chmyrov, A. ; Van Aert, S. ; Richards, B.S. ; Hudry, D.
Preventing cation intermixing enables 50% quantum yield in sub-15 nm short-wave infrared-emitting rare-earth based core-shell nanocrystals.Nawroth, J. ; Roth, D. ; van Schadewijk, A. ; Ravi, A. ; Maulana, T.I. ; Senger, C.N. ; van Riet, S. ; Ninaber, D.K. ; de Waal, A.M. ; Kraft, D. ; Hiemstra, P.S. ; Ryan, A.L. ; van der Does, A.M.
Breathing on chip: Dynamic flow and stretch accelerate mucociliary maturation of airway epithelium in vitroAlvarez, L. ; Marín-García, P.J. ; Rentero-Garrido, P. ; Martinez Jimenez, C.P. ; Llobat, L.
Interleukin 6 and interferon gamma haplotypes are related to cytokine serum levels in dogs in an endemic Leishmania infantum region.Kulaj, K. ; Harger, A. ; Bauer, M. ; Caliskan, Ö.S. ; Gupta, T.K. ; Chiang, D.M. ; Milbank, E. ; Reber, J. ; Karlas, A. ; Kotzbeck, P. ; Sailer, D.N. ; Volta, F. ; Lutter, D. ; Prakash, S. ; Merl-Pham, J. ; Ntziachristos, V. ; Hauner, H. ; Pfaffl, M.W. ; Tschöp, M.H. ; Müller, T.D. ; Hauck, S.M. ; Engel, B.D. ; Gerdes, J.M. ; Pfluger, P.T. ; Krahmer, N. ; Stemmer, K.
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.Strzelecki, M. ; Yin, K. ; Talavera Lopez, C.N. ; Martinez Jimenez, C.P.
Isolation of nuclei from flash-frozen liver tissue for single-cell multiomics.Border, R. ; Athanasiadis, G.I. ; Buil, A. ; Schork, A.J. ; Cai, N. ; Young, A.I. ; Werge, T. ; Flint, J. ; Kendler, K.S. ; Sankararaman, S. ; Dahl, A.W. ; Zaitlen, N.A.
Cross-trait assortative mating is widespread and inflates genetic correlation estimates.Chang, S. ; Fermani, F. ; Lao, C.L. ; Huang, L. ; Jakovcevski, M. ; Di Giaimo, R. ; Gagliardi, M. ; Menegaz, D. ; Hennrich, A.A. ; Ziller, M.J. ; Eder, M. ; Klein, R. ; Cai, N. ; Deussing, J.M.
Tripartite extended amygdala-basal ganglia CRH circuit drives locomotor activation and avoidance behavior.Gundlach, K.A. ; Nawroth, J. ; Kanso, E. ; Nasrin, F. ; Ruby, E.G. ; McFall-Ngai, M.
Ciliated epithelia are key elements in the recruitment of bacterial partners in the squid-vibrio symbiosis.Bauer, S. ; Eigenmann, J. ; Zhao, Y. ; Fleig, J. ; Hawe, J.S. ; Pan, C. ; Bongiovanni, D. ; Wengert, S. ; Ma, A.E. ; Lusis, A.J. ; Kovacic, J.C. ; Bjoerkegren, J.L.M. ; Maegdefessel, L. ; Schunkert, H. ; von Scheidt, M.
Identification of the transcription factor ATF3 as a direct and indirect regulator of the LDLR.Waibel, D.J.E. ; Atwell, S. ; Meier, M. ; Marr, C. ; Rieck, B.
Capturing shape information with multi-scale topological loss terms for 3D reconstruction.van den Hoek, H. ; Klena, N. ; Jordan, M.A. ; Viar, G.A. ; Righetto, R.D. ; Schaffer, M. ; Erdmann, P.S. ; Wan, W. ; Geimer, S. ; Plitzko, J.M. ; Baumeister, W. ; Pigino, G. ; Hamel, V. ; Guichard, P. ; Engel, B.D.
In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains.Dietrich, H.M. ; Righetto, R.D. ; Kumar, A. ; Wietrzynski, W. ; Trischler, R. ; Schuller, S.K. ; Wagner, J. ; Schwarz, F.M. ; Engel, B.D. ; Müller, V. ; Schuller, J.M.
Membrane-anchored HDCR nanowires drive hydrogen-powered CO2 fixation.Lamm, L. ; Righetto, R.D. ; Wietrzynski, W. ; Pöge, M. ; Martinez-Sanchez, A. ; Peng, T. ; Engel, B.D.
MemBrain: A deep learning-aided pipeline for detection of membrane proteins in Cryo-electron tomograms.Compera, N. ; Atwell, S. ; Wirth, J. ; von Toerne, C. ; Hauck, S.M. ; Meier, M.
Adipose microtissue-on-chip: A 3D cell culture platform for differentiation, stimulation, and proteomic analysis of human adipocytes.Waibel, D.J.E. ; Kiermeyer, N. ; Atwell, S. ; Sadafi, A. ; Meier, M. ; Marr, C.
SHAPR predicts 3D cell shapes from 2D microscopic images.An, U. ; Cai, N. ; Dahl, A. ; Sankararaman, S.
AutoComplete: Deep learning-based phenotype imputation for large-scale biomedical data.Cocina, A. ; Brechbühler, R. ; Vonk, S.J.W. ; Cui, J. ; Rossinelli, A.A. ; Rojo, H. ; Rabouw, F.T. ; Norris, D.J.
Nanophotonic approach to study excited-state dynamics in semiconductor nanocrystals.Trujillo, J.T. ; Long, J. ; Aboelnour, E. ; Ogas, J. ; Wisecaver, J.H.
CHD chromatin remodeling protein diversification yields novel clades and domains absent in classic model organisms.Wagner, S. ; Matek, C. ; Shetab Boushehri, S. ; Boxberg, M. ; Lamm, L. ; Sadafi, A. ; Waibel, D.J.E. ; Marr, C. ; Peng, T.
Make deep learning algorithms in computational pathology more reproducible and reusable.Han, X. ; Yu, Z. ; Zhuo, Y. ; Zhao, B. ; Ren, Y. ; Lamm, L. ; Xue, X. ; Feng, J. ; Marr, C. ; Shan, F. ; Peng, T. ; Zhang, X.Y.
The value of longitudinal clinical data and paired CT scans in predicting the deterioration of COVID-19 revealed by an artificial intelligence system.Wolff, G. ; Sakurai, M. ; Mhamane, A. ; Troullinaki, M. ; Maida, A. ; Deligiannis, I.K. ; Yin, K. ; Weber, P. ; Morgenstern, J. ; Wieder, A. ; Kwon, Y. ; Sekar, R. ; Zeigerer, A. ; Roden, M. ; Blüher, M. ; Volk, N. ; Poth, T. ; Hackert, T. ; Wiedmann, L. ; De Angelis Rigotti, F. ; Rodriguez-Vita, J. ; Fischer, A. ; Mukthavaram, R. ; Limphong, P. ; Tachikawa, K. ; Karmali, P. ; Payne, J. ; Chivukula, P. ; Ekim Üstünel, B. ; Martinez Jimenez, C.P. ; Szendrödi, J. ; Nawroth, P.P. ; Herzig, S.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.Scaltsoyiannes, V. ; Corre, N. ; Waltz, F. ; Giegé, P.
Types and functions of mitoribosome-specific ribosomal proteins across eukaryotes.Yin, K. ; Patten, D. ; Gough, S.C. ; de Barros Gonçalves, S. ; Chan, A. ; Olan, I. ; Cassidy, L. ; Poblocka, M. ; Zhu, H. ; Lun, A. ; Schuijs, M.J. ; Young, A. ; Martinez Jimenez, C.P. ; Halim, T.Y.F. ; Shetty, S. ; Narita, M. ; Hoare, M.
Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance.Aellen, M. ; Rossinelli, A.A. ; Keitel, R.C. ; Brechbühler, R. ; Antolinez, F.V. ; Rodrigo, S.G. ; Cui, J. ; Norris, D.J.
Role of gain in Fabry-Pérot surface plasmon polariton lasers.Ma, R. ; Yu, H. ; Ma, Q. ; Zhou, Q. ; Ni, K.
Angular velocity measurement with wide range based on dual-comb Sagnac interferometer.Schork, A.J. ; Peterson, R.E. ; Dahl, A. ; Cai, N. ; Kendler, K.S.
Author Correction: Indirect paths from genetics to education (Nature Genetics, (2022), 54, 4, (372-373), 10.1038/s41588-021-00999-5).Falkai, P. ; Koutsouleris, N. ; Bertsch, K. ; Bialas, M. ; Binder, E. ; Bühner, M. ; Buyx, A. ; Cai, N. ; Cappello, S. ; Ehring, T. ; Gensichen, J. ; Hamann, J. ; Hasan, A. ; Henningsen, P. ; Leucht, S. ; Möhrmann, K.H. ; Nagelstutz, E. ; Padberg, F. ; Peters, A. ; Pfäffel, L. ; Reich-Erkelenz, D. ; Riedl, V. ; Rueckert, D. ; Schmitt, A. ; Schulte-Körne, G. ; Scheuring, E. ; Schulze, T.G. ; Starzengruber, R. ; Stier, S. ; Theis, F.J. ; Winkelmann, J. ; Wurst, W. ; Priller, J.
Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health.Bandi, V.G. ; Luciano, M.P. ; Saccomano, M. ; Patel, N.L. ; Bischof, T.S. ; Lingg, J.G.P. ; Tsrunchev,P. ; Nix, M.N. ; Ruehle, B. ; Sanders, C. ; Riffle, L. ; Robinson, C.M. ; Difilippantonio, S. ; Kalen, J.D. ; Resch-Genger, U. ; Ivanic, J. ; Bruns, O.T. ; Schnermann, M.J.
Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines.Noack, F. ; Vangelisti, S. ; Raffl, G. ; Moreira Carido Pereira, M. ; Diwakar, S.J. ; Chong, F. ; Bonev, B.
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler.Schork, A.J. ; Peterson, R.E. ; Dahl, A. ; Cai, N. ; Kendler, K.S.
Indirect paths from genetics to education.Righetto, R.D. ; Engel, B.D.
Expanding the arsenal of bacterial spearguns.Righetto, R.D. ; Engel, B.D.
Publisher Correction: Expanding the arsenal of bacterial spearguns (Nature Microbiology, (2022), 7, 3, (363-364), 10.1038/s41564-022-01078-z).Nguyen, T.D. ; Harder, A. ; Xiong, Y. ; Kowalec, K. ; Hägg, S. ; Cai, N. ; Kuja-Halkola, R. ; Dalman, C. ; Sullivan, P.F. ; Lu, Y.
Genetic heterogeneity and subtypes of major depression.Zou, J. ; Gopalakrishnan, S. ; Parker, C.C. ; Nicod, J. ; Mott, R. ; Cai, N. ; Lionikas, A. ; Davies, R.W. ; Palmer, A.A. ; Flint, J.
Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility.Breunig, M. ; Merkle, J. ; Melzer, M.K. ; Heller, S. ; Seufferlein, T. ; Meier, M. ; Hohwieler, M. ; Kleger, A.
Differentiation of human pluripotent stem cells into pancreatic duct-like organoids.Salinas-Giegé, T. ; Englmeier, R. ; Meichel, H. ; Soufari, H. ; Kühn, L. ; Pfeffer, S. ; Förster, F. ; Engel, B.D. ; Giegé, P. ; Drouard, L. ; Hashem, Y. ; Waltz, F.
How to build a ribosome from RNA fragments in Chlamydomonas mitochondria.Neiburga, K.D. ; Vilne, B. ; Bauer, S. ; Bongiovanni, D. ; Ziegler, T. ; Lachmann, M. ; Wengert, S. ; Hawe, J.S. ; Güldener, U. ; Westerlund, A. ; Li, L. ; Pang, S. ; Yang, C. ; Saar, K. ; Huebner, N. ; Maegdefessel, L. ; Lange, R. ; Krane, M. ; Schunkert, H. ; von Scheidt, M.
Vascular tissue specific mirna profiles reveal novel correlations with risk factors in coronary artery disease.Ardila Riveros, J.C. ; Blöchinger, A. ; Atwell, S. ; Moussus, M. ; Compera, N. ; Rajabnia, O. ; Georgiev, T. ; Lickert, H. ; Meier, M. ; Lickert, H.
Automated optimization of endoderm differentiation on chip.Aboelnour, E. ; Bonev, B.
Evolutionary conservation and cell type specificity of nuclear compartments in the brain.Merkle, J. ; Breunig, M. ; Schmid, M. ; Allgöwer, C. ; Krüger, J. ; Melzer, M.K. ; Bens, S. ; Siebert, R. ; Perkhofer, L. ; Azoitei, N. ; Seufferlein, T. ; Heller, S. ; Meier, M. ; Müller, M. ; Kleger, A. ; Hohwieler, M.
Cdkn2a-mutated pancreatic ductal organoids from induced pluripotent stem cells to model a cancer predisposition syndrome.Höfler, M.V. ; Hoinka, N. ; Schäfer, T. ; Horn, M. ; Aussenac, F. ; Fuhrmann-Lieker, T. ; Gutmann, T.
Light amplification materials based on biopolymers doped with dye molecules - structural insights from 15N and 13C solid-state dynamic nuclear polarization.Keitel, R.C. ; Aellen, M. ; Feber, B.L. ; Rossinelli, A.A. ; Meyer, S.A. ; Cui, J. ; Norris, D.J.
Active mode switching in plasmonic microlasers by spatial control of optical gain.Moebel, E. ; Martinez-Sanchez, A. ; Lamm, L. ; Righetto, R.D. ; Wietrzynski, W. ; Albert, S. ; Larivière, D. ; Fourmentin, E. ; Pfeffer, S. ; Ortiz, J. ; Baumeister, W. ; Peng, T. ; Engel, B.D. ; Kervrann, C.
Author Correction: Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms (Nature Methods, (2021), 18, 11, (1386-1394), 10.1038/s41592-021-01275-4).Moebel, E. ; Martinez-Sanchez, A. ; Lamm, L. ; Righetto, R.D. ; Wietrzynski, W. ; Albert, S. ; Larivière, D. ; Fourmentin, E. ; Pfeffer, S. ; Ortiz, J. ; Baumeister, W. ; Peng, T. ; Engel, B.D. ; Kervrann, C.
Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms.Cai, N. ; Gomez-Duran, A. ; Yonova-Doing, E. ; Kundu, K. ; Burgess, A.I. ; Golder, Z.J. ; Calabrese, C. ; Bonder, M.J. ; Camacho, M. ; Lawson, R.A. ; Li, L. ; Williams-Gray, C.H. ; ICICLE-PD Study Group ; di Angelantonio, E. ; Roberts, D.J. ; Watkins, N.A. ; Ouwehand, W.H. ; Butterworth, A.S. ; Stewart, I.D. ; Pietzner, M. ; Wareham, N.J. ; Langenberg, C. ; Walter, K. ; Rothwell, P.M. ; Howson, J.M.M. ; Stegle, O. ; Chinnery, P.F. ; Soranzo, N.
Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases.Siehler, J. ; Blöchinger, A. ; Meier, M. ; Lickert, H.
Engineering islets from stem cells for advanced therapies of diabetes.Richter, M. ; Deligiannis, I.K. ; Yin, K. ; Danese, A. ; Lleshi, E. ; Coupland, P. ; Vallejos, C.A. ; Matchett, K.P. ; Henderson, N.C. ; Colomé-Tatché, M. ; Martinez Jimenez, C.P.
Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy.Wietrzynski, W. ; Traverso, E. ; Wollman, F.A. ; Wostrikoff, K.
The state of oligomerization of Rubisco controls the rate of synthesis of the Rubisco large subunit in Chlamydomonas reinhardtii.Compera, N. ; Atwell, S. ; Wirth, J. ; Wolfrum, B. ; Meier, M.
Upscaling of pneumatic membrane valves for the integration of 3D cell cultures on chip.Wiedenmann, S. ; Breunig, M. ; Merkle, J. ; von Toerne, C. ; Georgiev, T. ; Moussus, M. ; Schulte, L.N. ; Seufferlein, T. ; Sterr, M. ; Lickert, H. ; Weissinger, S.E. ; Möller, P. ; Hauck, S.M. ; Hohwieler, M. ; Kleger, A. ; Meier, M.
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip.Gupta, T.K. ; Klumpe, S. ; Gries, K. ; Heinz, S. ; Wietrzynski, W. ; Ohnishi, N. ; Niemeyer, J. ; Spaniol, B. ; Schaffer, M. ; Rast, A. ; Ostermeier, M. ; Strauss, M. ; Plitzko, J.M. ; Baumeister, W. ; Rudack, T. ; Sakamoto, W. ; Nickelsen, J. ; Schuller, J.M. ; Schroda, M. ; Engel, B.D.
Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity.Moussus, M. ; Meier, M.
A 3D-printed Arabidopsis thaliana root imaging platform.Breunig, M. ; Merkle, J. ; Wagner, M. ; Melzer, M.K. ; Barth, T.F.E. ; Engleitner, T. ; Krumm, J. ; Wiedenmann, S. ; Cohrs, C.M. ; Perkhofer, L. ; Jain, G. ; Krüger, J. ; Hermann, P.C. ; Schmid, M. ; Madácsy, T. ; Varga, A. ; Griger, J. ; Azoitei, N. ; Müller, M. ; Wessely, O. ; Robey, P.G. ; Heller, S. ; Dantes, Z. ; Reichert, M. ; Günes, C. ; Bolenz, C. ; Kuhn, F. ; Maléth, J. ; Speier, S. ; Liebau, S. ; Sipos, B. ; Kuster, B. ; Seufferlein, T. ; Rad, R. ; Meier, M. ; Hohwieler, M. ; Kleger, A.
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.Aboelnour, E. ; Bonev, B.
Decoding the organization, dynamics, and function of the 4D genome.Cosco, E. ; Arus, B.A. ; Spearman, A.L. ; Atallah, T.L. ; Lim, I. ; Leland, O.S. ; Caram, J.R. ; Bischof, T.S. ; Bruns, O.T. ; Sletten, E.M.
Bright chromenylium polymethine dyes enable fast, four-color in vivo imaging with shortwave infrared detection.Zabret, J. ; Bohn, S. ; Schuller, S.K. ; Arnolds, O. ; Möller, M. ; Meier-Credo, J. ; Liauw, P. ; Chan, A. ; Tajkhorshid, E. ; Langer, J.D. ; Stoll, R. ; Krieger-Liszkay, A. ; Engel, B.D. ; Rudack, T. ; Schuller, J.M. ; Nowaczyk, M.M.
Structural insights into photosystem II assembly.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wißmiller, K. ; von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.Bonder, M.J. ; Smail, C. ; Gloudemans, M.J. ; Frésard, L. ; Jakubosky, D. ; D'Antonio, M. ; Li, X. ; Ferraro, N.M. ; Carcamo-Orive, I. ; Mirauta, B. ; Seaton, D.D. ; Cai, N. ; Vakili, D. ; Horta, D. ; Zhao, C. ; Zastrow, D.B. ; Bonner, D.E. ; Wheeler, M.T. ; Kilpinen, H. ; Knowles, J.W. ; Smith, E.N. ; Frazer, K.A. ; Montgomery, S.B. ; Stegle, O.
Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics.Chatzinakos, C. ; Lee, D. ; Cai, N. ; Vladimirov, V.I. ; Webb, B.T. ; Riley, B.P. ; Flint, J. ; Kendler, K.S. ; Ressler, K.J. ; Daskalakis, N.P. ; Bacanu, S.A.
Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel.Ruiz Ojeda, F.J. ; Wang, J. ; Bäcker, T. ; Krueger, M. ; Zamani, S. ; Rosowski, S. ; Gruber, T. ; Onogi, Y. ; Feuchtinger, A. ; Schulz, T.J. ; Fässler, R. ; Müller, T.D. ; García-Cáceres, C. ; Meier, M. ; Blüher, M. ; Ussar, S.
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wissmiller, K. ; Gräfin von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Inceptor counteracts insulin signalling in β-cells to control glycaemia.Yu, Z. ; Han, X. ; Zhao, B. ; Zhuo, Y. ; Ren, Y. ; Xue, X. ; Lamm, L. ; Feng, J. ; Marr, C. ; Shan, F. ; Peng, T. ; Zhang, X.-Y.
DABC-Net for robust pneumonia segmentation and prediction of COVID-19 progression on chest CT scans.Fischer, A.W. ; Jaeckstein, M.Y. ; Gottschling, K. ; Heine, M. ; Sass, F. ; Mangels, N. ; Schlein, C. ; Worthmann, A. ; Bruns, O.T. ; Yuan, Y. ; Zhu, H. ; Chen, O. ; Ittrich, H. ; Nilsson, S.K. ; Stefanicka, P. ; Ukropec, J. ; Balaz, M. ; Dong, H. ; Sun, W. ; Reimer, R. ; Scheja, L. ; Heeren, J.
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation.Saif, M. ; Kwanten, W.J. ; Carr, J.A. ; Chen, I.X. ; Posada, J.M. ; Srivastava, A. ; Zhang, J. ; Zheng, Y. ; Pinter, M. ; Chatterjee, S. ; Softic, S. ; Kahn, C.R. ; van Leyen, K. ; Bruns, O.T. ; Jain, R.K. ; Bawendi, M.G.
Author Correction: Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin (Nature Biomedical Engineering, (2020), 4, 8, (801-813), 10.1038/s41551-020-0569-y).Peng, T. ; Lamm, L. ; Loeffler, D. ; Ahmed, N. ; Navab, N. ; Schroeder, T. ; Marr, C.
Background and illumination correction for time-lapse microscopy data with correlated foreground.Cosco, E. ; Spearman, A.L. ; Ramakrishnan, S. ; Lingg, J.G.P. ; Saccomano, M. ; Pengshung, M. ; Arus, B.A. ; Wong, K.C.Y. ; Glasl, S. ; Ntziachristos, V. ; Warmer, M. ; McLaughlin, R.R. ; Bruns, O.T. ; Sletten, E.M.
Shortwave infrared polymethine fluorophores matched to excitation lasers enable non-invasive, multicolour in vivo imaging in real time.He, S. ; Chou, H.T. ; Matthies, D. ; Wunder, T. ; Meyer, M.T. ; Atkinson, N. ; Martinez-Sanchez, A. ; Jeffrey, P.D. ; Port, S.A. ; Patena, W. ; He, G. ; Chen, V.K. ; Hughson, F.M. ; McCormick, A.J. ; Mueller-Cajar, O. ; Engel, B.D. ; Yu, Z. ; Jonikas, M.C.
The structural basis of Rubisco phase separation in the pyrenoid.Dong, Y. ; Han, Q. ; Ma, K. ; Song, F. ; Zheng, S. ; Ding, Y.
Study two kind different catalytic behaviors for K4H1.2[Co0.6(H2O)0.6SiW11.4O39.4]-cocatalyzed visible light driven water oxidation in pH 1–7 media.Szabo, Q. ; Donjon, A. ; Jerković, I. ; Papadopoulos, G.L. ; Cheutin, T. ; Bonev, B. ; Nora, E.P. ; Bruneau, B.G. ; Bantignies, F. ; Cavalli, G.
Regulation of single-cell genome organization into TADs and chromatin nanodomains.Chatzinakos, C. ; Georgiadis, F. ; Lee, D. ; Cai, N. ; Vladimirov, V.I. ; Docherty, A. ; Webb, B.T. ; Riley, B.P. ; Flint, J. ; Kendler, K.S. ; Daskalakis, N.P. ; Bacanu, S.A.
TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders.Klena, N. ; Le Guennec, M. ; Tassin, A.M. ; van den Hoek, H. ; Erdmann, P.S. ; Schaffer, M. ; Geimer, S. ; Aeschlimann, G. ; Kovacik, L. ; Sadian, Y. ; Goldie, K.N. ; Stahlberg, H. ; Engel, B.D. ; Hamel, V. ; Guichard, P.
Architecture of the centriole cartwheel-containing region revealed by cryo-electron tomography.Cai, N. ; Choi, K.W. ; Fried, E.I.
Reviewing the genetics of heterogeneity in depression: Operationalizations, manifestations, and etiologies.Saif, M. ; Kwanten, W.J. ; Carr, J.A. ; Chen, I.X. ; Posada, J.M. ; Srivastava, A. ; Zhang, J. ; Zheng, Y. ; Pinter, M. ; Chatterjee, S. ; Softic, S. ; Kahn, C.R. ; van Leyen, K. ; Bruns, O.T. ; Jain, R.K. ; Bawendi, M.G.
Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin.Zhao, S. ; Todorov, M.I. ; Cai, R. ; Ai-Maskari, R. ; Steinke, H. ; Kemter, E. ; Mai, H. ; Rong, Z. ; Warmer, M. ; Stanic Aguilera, K.N. ; Schoppe, O. ; Paetzold, J.C. ; Gesierich, B. ; Wong, M.N. ; Huber, T.B. ; Duering, M. ; Bruns, O.T. ; Menze, B. ; Lipfert, J. ; Puelles, V.G. ; Wolf, E. ; Bechmann, I. ; Ertürk, A.
Cellular and molecular probing of intact human organs.Kamies, R. ; Martinez Jimenez, C.P.
Advances of single-cell genomics and epigenomics in human disease: Where are we now?Wietrzynski, W. ; Schaffer, M. ; Tegunov, D. ; Albert, S. ; Kanazawa, A. ; Plitzko, J.M. ; Baumeister, W. ; Engel, B.D.
Charting the native architecture of Chlamydomonas thylakoid membranes with single-molecule precision.Cai, N. ; Revez, J.A. ; Adams, M.J. ; Andlauer, T.F.M. ; Breen, G. ; Byrne, E.M. ; Clarke, T.K. ; Forstner, A.J. ; Grabe, H.J. ; Hamilton, S.P. ; Levinson, D.F. ; Lewis, C.M. ; Lewis, G. ; Martin, N.G. ; Milaneschi, Y. ; Mors, O. ; Müller-Myhsok, B. ; Penninx, B.W.J.H. ; Perlis, R.H. ; Pistis, G. ; Potash, J.B. ; Preisig, M. ; Shi, J. ; Smoller, J.W. ; Streit, F. ; Tiemeier, H. ; Uher, R. ; Van der Auwera, S. ; Viktorin, A. ; Weissman, M.M. ; Kendler, K.S. ; Flint, J.
Minimal phenotyping yields genome-wide association signals of low specificity for major depression.Le Guennec, M. ; Klena, N. ; Gambarotto, D. ; Laporte, M.H. ; Tassin, A.M. ; van den Hoek, H. ; Erdmann, P.S. ; Schaffer, M. ; Kovacik, L. ; Borgers, S. ; Goldie, K.N. ; Stahlberg, H. ; Bornens, M. ; Azimzadeh, J. ; Engel, B.D. ; Hamel, V. ; Guichard, P.
A helical inner scaffold provides a structural basis for centriole cohesion.Wiener, J. ; Kokotek, D. ; Rosowski, S. ; Lickert, H. ; Meier, M.
Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics.Boxer, L.D. ; Renthal, W. ; Greben, A.W. ; Whitwam, T. ; Silberfeld, A. ; Stroud, H. ; Li, E. ; Yang, M.G. ; Kinde, B. ; Griffith, E.C. ; Bonev, B. ; Greenberg, M.E.
MeCP2 represses the rate of transcriptional initiation of highly methylated long genes.Schuller, J.M. ; Birrell, J.A. ; Tanaka, H. ; Konuma, T. ; Wulfhorst, H. ; Cox, N. ; Schuller, S.K. ; Thiemann, J. ; Lubitz, W. ; Sétif, P. ; Ikegami, T. ; Engel, B.D. ; Kurisu, G. ; Nowaczyk, M.M.
Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer.Antolinez, F.V. ; Winkler, J.M. ; Rohner, P. ; Kress, S.J.P. ; Keitel, R.C. ; Kim, D.K. ; Marques-Gallego, P. ; Cui, J. ; Rabouw, F.T. ; Poulikakos, D. ; Norris, D.J.
Defect-tolerant plasmonic elliptical resonators for long-range energy transfer.Chen, W. ; Cheng, C.A. ; Cosco, E. ; Ramakrishnan, A. ; Lingg, J.G.P. ; Bruns, O.T. ; Zink, J.I. ; Sletten, E.M.
Shortwave infrared imaging with J-aggregates stabilized in hollow mesoporous silica nanoparticles.Chen, H.C. ; Eling, N. ; Martinez Jimenez, C.P. ; O'Brien, L.M. ; Carbonaro, V. ; Marioni, J.C. ; Odom, D.T. ; de la Roche, M.
IL-7-dependent compositional changes within the gamma delta T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response.Rowlands, C.J. ; Bruns, O.T. ; Franke, D. ; Fukamura, D. ; Jain, R.K. ; Bawendi, M.G. ; So, P.T.C.
Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications.Karakus, U. ; Thamamongood, T. ; Ciminski, K. ; Ran, W. ; Günther, S.C. ; Pohl, M.O. ; Eletto, D. ; Jeney, C. ; Hoffmann, D. ; Reiche, S. ; Schinköthe, J. ; Ulrich, R. ; Wiener, J. ; Hayes, M.G.B. ; Chang, M.W. ; Hunziker, A. ; Yángüez, E. ; Aydillo, T. ; Krammer, F. ; Oderbolz, J. ; Meier, M. ; Oxenius, A. ; Halenius, A. ; Zimmer, G. ; Benner, C. ; Hale, B.G. ; García-Sastre, A. ; Beer, M. ; Schwemmle, M. ; Stertz, S.
MHC class II proteins mediate cross-species entry of bat influenza viruses.Schneider, N. ; Gäbelein, C. ; Wiener, J. ; Georgiev, T. ; Gobet, N. ; Weber, W. ; Meier, M.
Genetic code expansion method for temporal labeling of endogenously expressed proteins.Carr, J.A. ; Aellen, M. ; Franke, D. ; So, P.T.C. ; Bruns, O.T. ; Bawendi, M.G.
Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared.Martinez Jimenez, C.P. ; Eling, N. ; Chen, H.-C ; Vallejos, C.A. ; Kolodziejczyk, A.A. ; Connor, F. ; Stojic, L. ; Rayner, T.F. ; Stubbington, M.J.T. ; Teichmann, S.A. ; de la Roche, M. ; Marioni, J.C. ; Odom, D.T.
Aging increases cell-to-cell transcriptional variability upon immune stimulation.Schmidt, D. ; Wilson, M.D. ; Ballester, B. ; Schwalie, P.C. ; Brown, G.D. ; Marshall, A. ; Kutter, C. ; Watt, S. ; Martinez Jimenez, C.P. ; Mackay, S. ; Talianidis, I. ; Flicek, P. ; Odom, D.T.
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding.