Junior Group Vascular Epigenetics

The Vascular Epigenetics group elucidates the molecular mechanisms that underpin the complex interplay between metabolic, lifestyle and epigenetic factors. The group focuses on these themes in the context of vascular function and vascular disease. Using state-of-the-art techniques including single cell ChIP and RNA sequencing, mass-spectrometry based tracing of metabolic intermediates and chromatin modifications, light-sheet microscopy, in vivo disease models as well as high-throughput metabolic screening platforms, the group uses a highly integrative approach to understand complex pathologies. In close partnership with the University Hospital in Leipzig (Universitätsklinikum) and major pharmaceutical companies, we aim to translate our discoveries into effective therapies.