About our Research
Our team performs research in the area of molecular medicine with a focus on innate effector mechanisms of allergy, asthma and helminth infection.
Our team is particularly interested in uncovering the roles of eicosanoid lipid mediators and macrophages in type 2 immune responses in asthma, nasal polyposis and helminth infection. A particular focus is the identification and characterization of helminth molecules that regulate type 2 inflammatory diseases. As a second major aim, the team studies innate memory responses as a mechanism of chronic airway diseases. Ultimately, our team’s research is aimed at contributing to new therapeutic strategies to treat chronic airway inflammation.
Publications
Jargosch, M. ; Wasserer, S. ; Eigemann, J. ; Raunegger, T. ; Kurzen, N. ; Ding-Pfennigdorff, D. ; Bartnik, E. ; Schmidt-Weber, C.B. ; Biedermann, T. ; Eyerich, S. ; Eyerich, K. ; Florian, P. ; Herrmann, M. ; Saas, J. ; Lauffer, F.
Inhibition of RIPK1 prevents keratinocyte cell death and reduces skin inflammation in type 1 mediated chronic inflammatory skin diseases.Scala, E. ; Hillig, C. ; Mercurio, L. ; Fania, L. ; Gubinelli, E. ; Madonna, S. ; Menden, M.P. ; Eyerich, K. ; Eyerich, S. ; Albanesi, C.
331 IL-34 expression and function in hidradenitis suppurativa and psoriasis.Hübenthal, M. ; Klijnhout, J. ; Bogaard, E.v.d. ; Langreder, N. ; Eyerich, S. ; Strotton, M. ; Hartmann, J. ; Rintala, T. ; Fortino, V. ; Xing, H.
292 Role of innate immunity in molecular differentiation and mechanistic validation of endotypes of Atopic Dermatitis.