Computational Neurobiology
2020
- Arnold M, Nho K, Kueider-Paisley A, Massaro T, Huynh K, Brauner B, MahmoudianDehkordi S, Louie G, Moseley MA, Thompson JW, John-Williams LS, Tenenbaum JD, Blach C, Chang R, Brinton RD, Baillie R, Han X, Trojanowski JQ, Shaw LM, Martins R, Weiner MW, Trushina E, Toledo JB, Meikle PJ, Bennett DA, Krumsiek J, Doraiswamy PM, Saykin AJ, Kaddurah-Daouk R, Kastenmüller G (2020)
Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
Nature Communications: doi:10.1038/s41467-020-14959-w - Zhao N, Ren Y, Yamazaki Y, Qiao W, Li F, Felton LM, Mahmoudiandehkordi S, Kueider-Paisley A, Sonoustoun B, Arnold M, Shue F, Zheng J, Attrebi ON, Martens YA, Li Z, Bastea L, Meneses AD, Chen K, Tachibana M, Aikawa T, Oue H, Job L, Yamazaki A, Liu C, Storz P, Asmann YW, Ertekin-Taner N, Kanekiyo T, Kaddurah-Daouk R, and Bu G (2020)
Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways
2019
- AT Ahmed, S MahmoudianDehkordi, S Bhattacharyya, M Arnold, D Liu, D Neavin, MA Moseley, JW Thompson, L St John Williams, G Louie, MK Skime, L Wang, P Riva-Posse, W McDonald, WV Bobo, WE Craighead, R Krishnan, RM Weinshilboum, BW Dunlop, DS Millington, AJ Rush, MA Frye, R Kaddurah-Daouk, Mood Disorders Precision Medicine Consortium (2019)
Acylcarnitine Metabolomic Profiles Inform Clinically-Defined Major Depressive Phenotypes - Bernath MM, Bhattacharyya S, Nho K, Barupal DK, Fiehn O, Baillie R, Risacher SL, Arnold M, Jacobson T, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R, Saykin AJ for the Alzheimer's Disease Neuroimaging Initiative and the Alzheimer's Disease Metabolomics Consortium (2019)
Serum triglycerides in Alzheimer's disease: Relation to neuroimaging and CSF biomarkers - Barupal DK, Baillie R, Fan S, Saykin AJ, Meikle PJ, Arnold M, Nho K, Fiehn O, Kaddurah-Daouk R; for the Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium (2019)
Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology - St John-Williams L, Mahmoudiandehkordi S, Arnold M, Massaro T, Blach C, Kastenmüller G, Louie G, Kueider-Paisley A, Han X, Baillie R, Motsinger-Reif AA, Rotroff D, Nho K, Saykin AJ, Risacher SL, Koal T, Moseley MA, Tenenbaum JD, Thompson JW, Kaddurah-Daouk R; for the Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium (2019)
Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts - Nho K, Kueider-Paisley A, Ahmad S, MahmoudianDehkordi S, Arnold M, Risacher SL, Louie G, Blach C, Baillie R, Han X, Kastenmüller G, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, van Duijn C, Saykin AJ, Kaddurah-Daouk R; for the Alzheimer’s Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium (2019)
Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers - Bhattacharyya S, Ahmed AT, Arnold M, Liu D, Luo C, Zhu H, Mahmoudiandehkordi S, Neavin D, Louie G, Dunlop BW, Frye MA, Wang L, Weinshilboum RM, Krishnan RR, Rush AJ, Kaddurah-Daouk R (2019)
Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients
10.1038/s41398-019-0507-5
2018
- Mahmoudiandehkordi, S., M. Arnold, K. Nho, S. Ahmad, W. Jia, G. Xia, G. Louie, A. Kueider, M. A. Moseley, J. W. Thompson, L. St. John Williams, J. D. Tenenbaum, C. Blach, R. Baillie, X. Han, S. Bhattacharyya, J. B. Toledo, S. Schafferer, S. Klein, T. Koal, S. L. Risacher, M. A. Kling, A. Motsinger-Reif, D. M. Rotroff, J. Jack, T. Hankemeier, D. A. Bennett, P. L. De Jager, J. Q. Trojanowski, L. M. Shaw, M. W. Weiner, P. M. Doraiswamy, C. M. van Duijn, A. Saykin, G. Kastenmueller and R. Kaddurah-Daouk (2018)
Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease: An Emerging Role for Gut Microbiome - Nho, K., A. Kueider-Paisley, S. MahmoudianDehkord, M. Arnold, S. L. Risacher, G. Louie, C. Blach, R. Baillie, X. Han, G. Kastenmueller, W. Jia, G. Xie, S. Ahmad, T. Hankemeier, C. M. van Duijn, J. Q. Trojanowski, L. M. Shaw, M. W. Weiner, P. M. Doraiswamy, A. J. Saykin and R. Kaddurah-Daouk (2018)
Altered Bile Acid Profile in Mild Cognitive Impairment and Alzheimer’s Disease: Relationship to Neuroimaging and CSF Biomarkers - Varma VR, Oommen AM, Varma S, Casanova R, An Y, Andrews RM, O’Brien R, Pletnikova O, Troncoso JC, Toledo J, Baillie R, Arnold M, Kastenmueller G, Nho K, Doraiswamy PM, Saykin AJ, Kaddurah-Daouk R, Legido-Quigley C, Thambisetty M (2018)
Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
PLoS Medicine: doi:10.1371/journal.pmed.1002482 - Adler A, Kirchmeier P, Reinhard J, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Mewes HW, Arnold M, Ruepp A (2018)
PhenoDis: a comprehensive database for phenotypic characterization of rare cardiac diseases
Orphanet J Rare Dis: doi:10.1186/s13023-018-0765-y
2017
- Toledo JB, Arnold M, Kastenmüller G, Chang R, Baillie RA, Han X, Thambisetty M, Tenenbaum JD, Suhre K, Thompson JW, John-Williams LS, MahmoudianDehkordi S, Rotroff DM, Jack JR, Motsinger-Reif A, Risacher SL, Blach C, Lucas JE, Massaro T, Louie G, Zhu H, Dallmann G, Klavins K, Koal T, Kim S, Nho K, Shen L, Casanova R, Varma S, Legido-Quigley C, Moseley MA, Zhu K, Henrion MY, van der Lee SJ, Harms AC, Demirkan A, Hankemeier T, van Duijn CM, Trojanowski JQ, Shaw LM, Saykin AJ, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R; Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium (2017)
Metabolic network failures in Alzheimer's disease -- A biochemical road map
Alzheimer’s & Dementia: doi:10.1016/j.jalz.2017.01.020 - St John-Williams L, Blach C, Toledo JB, Rotroff DM, Kim S, Klavins K, Baillie R, Han X, Mahmoudiandehkordi S, Jack J, Massaro TJ, Lucas JE, Louie G, Motsinger-Reif AA, Risacher SL; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium, Saykin AJ, Kastenmüller G, Arnold M, Koal T, Moseley MA, Mangravite LM, Peters MA, Tenenbaum JD, Thompson JW, Kaddurah-Daouk R (2018)
Targeted metabolomics and medication classification data from participants in the ADNI1 cohort
Scientific Data: doi:10.1038/sdata.2017.140 - Suhre K, Arnold M, Bhagwat A, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MM, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J (2017)
Connecting genetic risk to disease endpoints through the human blood plasma proteome
Nature Communications: doi:10.1038/ncomms14357
2012-2016
- Fard D, Läer K, Rothämel T, Schürmann P, Arnold M, Cohen M, Vennemann M, Pfeiffer H, Bajanowski T, Pfeufer A, Dörk T, Klintschar M (2016)
Candidate gene variants of the immune system and sudden infant death syndrome
Int J Legal Med: doi:10.1007/s00414-016-1347-y - Raffler J, Friedrich N, Arnold M, Kacprowski T, Rueedi R, Altmaier E, Bergmann S, Budde K, Gieger C, Homuth G, Pietzner M, Römisch-Margl W, Strauch K, Völzke H, Waldenberger M, Wallaschofski H, Nauck M, Völker U, Kastenmüller G, Suhre K (2015)
Genome-wide association study with targeted and non-targeted NMR metabolomics identifies 15 novel loci of urinary human metabolic individuality
PLoS Genetics: doi:10.1371/journal.pgen.1005487 - Arnold M, Raffler J, Pfeufer A, Suhre K, Kastenmüller G (2015)
SNiPA: an interactive, genetic variant-centered annotation browser
Bioinformatics: doi:10.1093/bioinformatics/btu779 - Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E, The MuTHER Consortium, Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenmüller G, Spector TD, Soranzo N (2014)
An atlas of genetic influences on human blood metabolites.
Nature Genetics: doi:10.1038/ng.2982 - Wjst M, Sargurupremraj M, Arnold M (2013)
Genome-wide association studies in asthma: what they really told us about pathogenesis
Curr Opin Allergy Clin Immunol: doi:10.1097/ACI.0b013e32835c1674 - Arnold M, Hartsperger ML, Baurecht H, Rodríguez E, Wachinger B, Franke A, Kabesch M, Winkelmann J, Pfeufer A, Romanos M, Illig T, Mewes HW, Stümpflen V, Weidinger S (2012)
Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases
BMC Genomics: doi:10.1186/1471-2164-13-490 - Arnold M, Ellwanger DC, Hartsperger ML, Pfeufer A, Stümpflen V (2012)
Cis-Acting Polymorphisms Affect Complex Traits through Modifications of MicroRNA Regulation Pathways
PLoS ONE: doi:10.1371/journal.pone.0036694
