Curation of Human Disease Networks

Welcome to the Curation of Human Disease Networks Group

Advances in medical research revealed that a disease phenotype is the result of pathobiological processes that interact in complex networks. A large body of information that was generated in decades of experimental research is hidden in the scientific literature.

Our aim is to generate high-quality databases that describe experimentally validated interactions between molecules and processes involved in the development of diseases. In our group, experienced curators extract knowledge from scientific articles and collect information in structured and user-friendly databases. The manual approach allows not only to describe primary information but additionally to put the content into a biologically meaningful context. Validated datasets of high quality are invaluable knowledge bases for (i) experimentally working scientists, (ii) the analyses of data that are generated in systems biology and network medicine approaches and (iii) the generation of testable hypotheses.