Curation of Human Disease Networks

Dr. Gisela Fobo

Phone: +49 89 3187-49587
Building/Room: 56/148

Member of Research Group: Curation of Human Disease Networks

Curriculum Vitae

1978 – 1984    M. Sc. Nutritional Science, University of Hohenheim
                       (German degree: Diplom Ernährungswissenschaftler)
1984 – 1988    PhD Fraunhofer Institute for Interfacial Engineering and Biotechnology /
                       Univ. of Hohenheim, Inst. of Biological Chemistry and Nutritional Science
1988 – 1997    MIPS, Max Planck Institute of Biochemistry, Munich
Since 1998      IBIS, Helmholtz Zentrum Munich


Liu X, Baarsma HA, Thiam CH, Montrone C, Brauner B., Fobo G, Heier JS, Duscha S, Königshoff M, Angeli V, Ruepp A, Campillos M. Systematic identification of pharmacological targets from small-molecule phenotypic screens. Cell Chemical Biology. 2016 Sep

Xu T, Brandmaier S, Messias AC, Herder C, Draisma HH, Demirkan A, Yu Z, Ried JS, Haller T, Heier M, Campillos M, Fobo G, Stark R, Holzapfel C, Adam J, Chi S, Rotter M, Panni T, Quante AS, He Y, Prehn C, Roemisch-Margl W, Kastenmüller G, Willemsen G, Pool R, Kasa K, van Dijk KW, Hankemeier T, Meisinger C, Thorand B, Ruepp A, Hrabé de Angelis M, Li Y, Wichmann HE, Stratmann B, Strauch K, Metspalu A, Gieger C, Suhre K, Adamski J, Illig T, Rathmann W, Roden M, Peters A, van Duijn CM, Boomsma DI, Meitinger T, Wang-Sattler R. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care. 2015 Aug 5. pii: dc150658. [Epub ahead of print] PMID: 26251408

Altmaier E, Fobo G, Heier M, Thorand B, Meisinger C, Römisch-Margl W, Waldenberger M, Gieger C, Illig T, Adamski J, Suhre K, Kastenmüller G. Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism. Eur J Epidemiol. 2014 May;29(5):325-36. doi: 10.1007/s10654-014-9910-7. Epub 2014 May 10. PMID: 24816436

Lechner M, Höhn V, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Kastenmüller G, Waegele B, Ruepp A. CIDeR: multifactorial interaction networks in human diseases. Genome Biol. 2012 Jul 18;13(7):R62. doi: 10.1186/gb-2012-13-7-r62. PMID: 22809392

Ruepp A, Kowarsch A, Schmidl D, Bruggenthin F, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Theis FJ. PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes. Genome Biol. 2010 Jan 20;11(1):R6

Smialowski P, Pagel P, Wong P, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Rattei T, Frishman D, Ruepp A. The Negatome database: a reference set of non-interacting protein pairs. Nucleic Acids Res. 2010 Jan;38(Database issue):D540-4

Ruepp A, Waegele B, Lechner M, Brauner B, Dunger-Kaltenbach I, Fobo G, Frishman G, Montrone C, Mewes HW. CORUM: the comprehensive resource of mammalian protein complexes--2009. Nucleic Acids Res. 2010 Jan;38(Database issue):D497-501

Waegele B, Dunger-Kaltenbach I, Fobo G, Montrone C, Mewes HW, Ruepp A. CRONOS: the cross-reference navigation server. Bioinformatics. 2009 Jan 1;25(1):141-3.

Andreas Ruepp, Octave Noubibou Doudieu, Jos van den Oever, Barbara Brauner, Irmtraud Dunger-Kaltenbach, Gisela Fobo, Goar Frishman, Corinna Montrone, Christine Skornia, Steffi Wanka, Thomas Rattei, Philipp Pagel, M. Louise Riley, Dmitrij Frishman, Dimitrij Surmeli, Igor V. Tetko, Matthias Oesterheld, Volker Stuempflen, Hans-Werner Mewes . The Mouse Functional Genome Database (MfunGD): functional annotation of proteins in the light of their cellular context. Nucleic Acids Research 34(Database-Issue): 568-571 (2006)

Igor V. Tetko, Barbara Brauner, Irmtraud Dunger-Kaltenbach, Goar Frishman, Corinna Montrone, Gisela Fobo, Andreas Ruepp, Alexey V. Antonov, Dimitrij Surmeli, Hans-Werner Mewes. MIPS bacterial genomes functional annotation benchmark dataset. Bioinformatics 21(10): 2520-2521 (2005)

Thuemmler F., Algarra P., Fobo G.M. Sequence similarities of phytochrome to protein kinases: implication for the structure, function and evolution of the phytochrome gene family. FEBS Lett. 1995; 357:149-155.

Ackermann H.W., Elzanowski A., Fobo G., Stewart G. Relationships of tailed phages: a survey of protein sequence identity. Arch. Virol. 1995; 140:1871-1884.

Dujon B., Alexandraki D.,...Fobo G.M.,...Becker I., Mewes H.W. Complete DNA sequence of yeast chromosome XI. Nature 1994; 369:371-378.

Feldmann H., Aigle M.,...Fobo G.M.,...Mewes H.W., Kleine K. Complete DNA sequence of yeast chromosome II. EMBO J. 1994; 13:5795-5809.

Kulbe K.D., Heinzler A., Knopki G.  Enzymatic synthesis of L-ascorbic acid via D-uronic acids; membrane-reactor integrated recovery of D-galacturonic acid from pectin hydrolysates. Ann. N. Y. Acad. Sci. 1987; 506:543-551.

Benedikter H., Knopki G., Renz P.  Phosphatidylinositol-specific phospholipase C from bovine blood platelets. Inhibition by calmodulin-inhibitors--activation by ATP and ADP. Z. Naturforsch. [C]. 1985; 40:68-72.

Patent:  Verfahren zur intrasequentiellen Cofaktor-Regeneration bei enzymatischen Synthesen, insbesondere bei der Herstellung von Vitamin C DE 35 02 141 C2