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Helmholtz Munich | ©Anna Tenditnaya

Dimitris Gorpas, PhD

Group Leader Fluorescence Imaging

Fluorescence Molecular Imaging, through its “red-flag” operation, enables earlier, faster, and personalized disease detection and surgical guidance.

Fluorescence Molecular Imaging, through its “red-flag” operation, enables earlier, faster, and personalized disease detection and surgical guidance.

CV

Dr. Dimitris Gorpas studied Electrical and Computer Engineering in the Department of Electrical and Computer Engineering at the Technical University of Athens, Greece. After his graduation, he obtained a Ph.D. in Engineering from the same institution. He went on to work as a postdoctoral research fellow to the Information Technologies Institute, Centre for Research and Technology, Hellas, Thessaloniki, Greece. In 2013, he moved to the Department of Biomedical Engineering at the University of California, Davis as a postdoctoral research employee. Since 2016, he is leading the Fluorescence Imaging group at the Chair of Biological Imaging and Center for Translational Cancer Research (TranslaTUM) of the Technical University of Munich, as well as the affiliated Institute for Biological and Medical Imaging at the Helmholtz Zentrum München. His scientific interests include the development of medical intraoperative and endoscopic imaging systems, their clinical validation, and surgical guidance through optical measurements. The aim of this research is to improve understanding of optical properties of tissue and their variation in relation to structural, molecular, and biochemical or functional parameters. The ultimate goal is the development of comprehensive imaging technologies to provide physicians innovative tools for diagnostic and therapeutic purposes.

Fields of Work and Expertise

Fluorescence Molecular ImagingMedical ImagingPhotonicsClinical TranslationStandardizationImage and Video Processing Computer/Robotic Vision

Personal Background

2016 - present

Group Leader, Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany (01/17-present / Permanent Contract), and Chair of Biological Imaging, Technical University of Munich, Munich, Germany (01/16-12/16).

2013-2015

Postdoctoral Research Employee, Department of Biomedical Engineering, University of California - Davis, Davis, California, USA.

2012-2013

Postdoctoral Research Fellow, Information Technologies Institute (ITI), Centre for Research and Technology, Hellas (CERTH), Thessaloniki, Greece.

11/10-08/11

Mandatory military service in Greece.

2003-2010

Ph.D. in Engineering, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

1998-2003

Diploma in Electrical and Computer Engineering, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

Honors and Awards

  • Recipient of special payment for outstanding scientific performance in 2018, Helmholtz Munich, Munich, Germany.
    2019

  • Award for "Excellence in Leadership and Grantsmanship", Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany.
    2018

  • Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
    2009

  • International SPIE Scholarship in Optical Science and Engineering.03/08–08/08 Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
    2009

  • Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
    2008

  • "Progress of Science" awards, Thomaidio Foundation, National Technical University of Athens, Greece. One of my publications (4 in total) was awarded each year.
    2005-2008

  • National Technical University of Athens scholarship for PhD students.
    2004-2008

  • Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
    2003-2004

Gold Star Awards Luxury Background
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Publications

2022 J Biomed

Sterkenburg, A.J., Hooghiemstra, W.T.R., Schmidt, I., Ntziachristos, V., Nagengast, W.B., Gorpas, D. (2022). Standardization and implementation of fluorescence molecular endoscopy in the clinic.

2022 Eur J Nucl Med Mol Imaging 49

Fang, H.-Y., Stangl, S., Marcazzan, S., Carvalho, M.J.B., Baumeister, T., Anand, A., Strangmann, J., Huspenina, J.S., Wang, T.C., Schmid, R.M., Feith, M., Friess, H., Ntziachristos, V., Multhoff, G., Gorpas, D., Quante, M. (2022). Targeted Hsp70 fluorescence molecular endoscopy detects dysplasia in Barrett’s esophagus.

2020 IEEE Trans Biomed Eng 67

Gorpas, D., Koch, M., Anastasopoulou, M., Bozhko, D., Klemm, U., Nieberler, M., Ntziachristos, V. (2020). Multi-Parametric Standardization of Fluorescence Imaging Systems Based on a Composite Phantom.

2019 Gut 68

Nagengast, W.B., Hartmans, E., Garcia-Allende, P.B., Peters, F.T.M., Linssen, M.D., Koch, M., Koller, M., Tjalma, J.J.J., Karrenbeld, A., Jorritsma-Smit, A., Kleibeuker, J.H., van Dam, G.M., Ntziachristos, V. (2019). Near-infrared fluorescence molecular endoscopy detects dysplastic oesophageal lesions using topical and systemic tracer of vascular endothelial growth factor A.

2019 Sci Rep 9

Gorpas, D., Phipps, J., Bec, J., Ma, D., Dochow, S., Yankelevich, D., Sorger, J., Popp, J., Bewley, A., Gandour-Edwards, R., Marcu, L., Farwell, D.G. (2019). Autofluorescence lifetime augmented reality as a means for real-time robotic surgery guidance in human patients.

2018 J Biophotonics 11

Bozhko, D., Karlas, A., Gorpas, D., Ntziachristos, V. (2018). Optoacoustic sensing of hematocrit to improve the accuracy of hybrid fluorescence-ultrasound intravascular imaging.

2018 Med Phys 45

Pogue, B.W., Zhu, T.C., Ntziachristos, V., Paulsen, K.D., Wilson, B.C., Pfefer, J., Nordstrom, R.J., Litorja, M., Wabnitz, H., Chen, Y., Gioux, S., Tromberg, B.J., Yodh, A.G. (2018). Fluorescence-guided surgery and intervention — An AAPM emerging technology blue paper.

2018 Nat Photonics 12

Koch, M., Symvoulidis, P., Ntziachristos, V. (2018). Tackling standardization in fluorescence molecular imaging.

2017 Cancer Res 77

Koch, M., de Jong, J.S., Glatz, J., Symvoulidis, P., Lamberts, L.E., Adams, A.L.L., Kranendonk, M.E.G., Terwisscha van Scheltinga, A.G.T., Aichler, M., Jansen, L., de Vries, J., Lub-de Hooge, M.N., Schröder, C.P., Jorritsma-Smit, A., Linssen, M.D., de Boer, E., van der Vegt, B., Nagengast, W.B., Elias, S.G., Oliveira, S., Witkamp, A.J., Mali, W.P.T.M., Van der Wall, E., Garcia-Allende, P.B., van Diest, P.J., de Vries, E.G.E., Walch, A., van Dam, G.M., Ntziachristos, V. (2017). Threshold Analysis and Biodistribution of Fluorescently Labeled Bevacizumab in Human Breast Cancer.

2017 J Biomed Opt 22

Gorpas, D., Koch, M., Anastasopoulou, M., Klemm, U., Ntziachristos, V. (2017). Benchmarking of fluorescence cameras through the use of a composite phantom.

Network

• Member of the European Society for Molecular Imaging (ESMI).
• Member of the Institute of Electrical and Electronics Engineers (IEEE).
• Member of the IEEE Engineering in Medicine and Biology Society.
• Member of the Society of Photo-Optical Instrumentation Engineers (SPIE).
• Member of Optica (formely OSA).
• Member of the Institute for Systems and Technologies of Information, Control and Communication (INSTICC).