Technological developments

Besides our strong research in protein engineering, we also engage in the development of infrastructure for optoacoustic spectroscopy and screening. For example, we developed a three-modality spectrometer allowing us to read the absorbance, fluorescence and optoacoustics spectra of a sample providing insight into its photophysics and new vantage points for the development of the agents.

1. Fuenzalida Werner JP, Huang Y, Mishra K, Janowski R, Vetschera P, Heichler C, Chmyrov A, Neufert C, Niessing D, Ntziachristos V, Stiel AC. Challenging a Preconception: Optoacoustic Spectrum Differs from the Optical Absorption Spectrum of Proteins and Dyes for Molecular Imaging. Chem. 2020. 92(15):10717-10724

1. Seeger M, Stiel AC*, Ntziachristos V*. In vitro optoacoustic flow cytometry with light scattering referencing. Sci Rep. 11(1):2181