Source: HMGU

Dr. Matthias Heinig
Junior Group Leader

Phone: +49 89 3187-2434
Fax: +49-89-3187-3369
Building/Room: 58a / 104

Google Scholar Profile

ResearchGate Profile



2006‑2010PhD in the labs of Norbert Hübner (Max Delbrück Center for molecular medicine Berlin) and Martin Vingron (Max Planck Insitiute for molecular genetics / Free University Berlin)
2003‑2005M.Sc. Bioinformatics FU Berlin
2000‑2003B.Sc. Bioinformatics LMU / TUM in Munich


Professional appointments 

2015‑nowGroup leader Genetic and Epigenetic Gene Regulation at the ICB, HMGU
2010‑2015Postdoctoral fellow at the department of computational molecular biology Max Planck Institute for molecular genetics Berlin
2005‑2006Research associate in the group of Vincent Schächter at CNRG Evry, France


Selected publications

Heinig M*, Adriaens ME*, Schafer S*, van Deutekom HWM, Lodder EM, Ware JS, Schneider V, Felkin LE, Creemers EE, Meder B, Katus HA, Rühle F, Stoll M, Cambien F, Villard E, Charron P, Varro A, Bishopric NH, George AL Jr, Dos Remedios C, Moreno-Moral A, Pesce F, Bauerfeind A, Rüschendorf F, Rintisch C, Petretto E, Barton PJ, Cook SA, Pinto YM, Bezzina CR, Hubner N. Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy. Genome Biol. 2017; 18:170 

Budach S, Heinig M*, Marsico A*. Principles of microRNA Regulation Revealed Through Modeling microRNA Expression Quantitative Trait LociGenetics. 2016; pii: genetics.116.187153.

Heinig M, Colome-Tatche M, Rintisch C, Schäfer S, Pravenec M, Hubner N, Vingron M, Johannes F. histoneHMM: Differential analysis of histone modifications with broad genomic footprints. BMC Bioinformatics 2015; 16:60

Rintisch C*, Heinig M*, Bauerfeind A, Schafer S, Mieth C, Patone G, Hummel O, Chen W, Cook S, Cuppen E, Colome-Tatche M, Johannes F, Jansen RC, Neil H, Werner M, Pravenec M, Vingron M, and Hubner N. Natural variation of histone modification and its impact on gene expression in the rat genome. Genome Res. 2014; 24(6):942-53

Heinig M*, Petretto E*, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R, Langley SR, Bauerfeind A, Hummel O, Lee YA, Paskas S, Rintisch C, Saar K, Cooper J, Buchan R, Gray EE, Cyster JG; Cardiogenics Consortium, Erdmann J, Hengstenberg C, Maouche S, Ouwehand WH, Rice CM, Samani NJ, Schunkert H, Goodall AH, Schulz H, Roider HG, Vingron M, Blankenberg S, Münzel T, Zeller T, Szymczak S, Ziegler A, Tiret L, Smyth DJ, Pravenec M, Aitman TJ, Cambien F, Clayton D, Todd JA, Hubner N, Cook SA. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature. 2010; 467(7314):460-4

Manke T*, Heinig M*, and Vingron M. Quantifying the effect of sequence variation on regulatory interactions. Hum Mutat. 2010; 31(4):477-83

* authors contributed equally to the work