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Lea Schuh
PhD candidate

E-mail
Building/Room: 58a/011

Curriculum Vitae

After graduating from the Oslo International School, Oslo, Norway, Lea Schuh studied mathematics in her bachelor's and master's at the Technical University of Munich (October 2013 - November 2018). For her master's thesis, she joined the lab of Arjun Raj, University of Pennsylvania, Philadelphia, PA, USA, for six months (April 2018 - October 2018). There she developed a mathematical model to investigate rare, correlated high-gene expression states as observed in pre-resistant melanoma cells. In December 2018, she then started her PhD at the Institute of Computational Biology, Helmholtz Zentrum München, in the group of Dr. Carsten Marr, Quantitative Single Cell Dynamics. During her PhD, she is using mathematical modeling to gain insights into gene expression regulation at the single-cell level. 

Publications

Schuh, L., Saint-Antoine, M., Sanford, E., Emert, B. L., Vargas-Garcia, C. A., Singh, A., Marr, C., Raj, A., Goyal, Y. Gene networks with transcriptional bursting recapitulate rare transient coordinated expression states in cancer. 2020. Cell Systems.

Schuh, L., Loos, C., Pokrovsky, D., Imhof, A., Rupp, R. A. W., Marr, C. H4K20 methylation kinetics are differently regulated by dilution and demethylation in proliferating and cell-cycle arrested Xenopus embryos. 2020. Cell Systems.

Alabert, C., Loos, C., Voelker-Albert, M., Graziano, S., Forne I., Reveron-Gomez, N., Schuh, L., Hasenauer, J., Marr, C., Imhof A., Groth, A. Domain model explains propagation dynamics and stability of K27 and K36 methylation landscapes. 2020. Cell Reports. 

Awards

2020: Add-on Fellowship for Interdisciplinary Life Science, Joachim Herz Stiftung 

2020: Award of Gerstetten's industry, City of Gerstetten

2020: Global Challenges for Women in Math Science Entrepreneurial Award 2020, Technical University of Munich

2019: Global Challenges for Women in Math Science Entrepreneurial Award 2019, Technical University of Munich

April 2018 - October 2018: PROMOS fellowship, DAAD (German Academic Exchange Service)