Computational Biomedicine

Publications

Author links open overlay panelaA

According to Google Scholar, our work has accumulated > 4,200 citations and h-index of 18. The total Research Interest (full-text reads and citations) of my work is higher than 95% compared to other researchers on ResearchGate. 

SELECTED PUBLICATIONS: 

Lina Keutzer*, Huifang You*, Ali Farnoud, Joakim Nyberg, Sebastian G. Wicha,
Gareth Maher-Edwards
, Georgios Vlasakakis, Gita Khalili Moghaddam, Elin M. SvenssonMichael P. Menden Ulrika S. H. Simonsson# and on behalf of the UNITE4TB Consortium
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampici
Pharmaceutics (2022)


Ali Farnoud, Alexander J. Ohnmacht, Martin Meinel, Michael P. Menden# 
Can artificial intelligence accelerate preclinical drug discovery and precision medicine?
Expert Opinion on Drug Discovery (2022)

Johanna Erber, Verena Kappler, Bernhard Haller, Hrvoje Mijočević, Ana Galhoz, Clarissa Prazeres da Costa, Friedemann Gebhardt, Natalia Graf, Dieter Hoffmann, Markus Thaler, Elke Lorenz, Hedwig Roggendorf, Florian Kohlmayer, Andreas Henkel, Michael P. Menden, Jürgen Ruland, Christoph D. Spinner, Ulrike Protzer*, Percy Knolle*, Paul Lingor*#, and on behalf of the SeCoMRI Study Group
Infection Control Measures and Prevalence of SARS-COV-2 IgG among 4,554 University Hospital Employees, Munich Germany
Emerging Infectious Diseases (2022)

Lucas Caldi Gomes*, Ana Galhoz*, Gaurav Jain, Anna-Elisa Roser, Fabian MaassEleonora Carboni, Elisabeth BarskiChristof Lenz, Katja Lohmann, Christine Klein, Mathias Bähr, André Fischer,  Michael P. Menden*Paul Lingor*#
Multi-omic landscaping of human midbrains identifies neuroinflammation as major disease mechanism in advanced-stage Parkinson’s disease. 
Clinical and Translational Medicine (2022)

Phong B. H. Nguyen*, Alexander J. Ohnmacht*, Samir Sharifli, Mathew J. Garnett and Michael P. Menden#
Inferred Ancestral Origin of Cancer Cell Lines Associates with Differential Drug Response
International Journal of Molecular Science 2021

Fabio Boniolo*, Emilio Dorigatti*, Alexander J. Ohnmacht*, Dieter Saur, Benjamin Schubert# & Michael P. Menden#
Artificial Intelligence in early drug discovery enabling precision medicine
Expert Opinion on Drug Discovery 2021

Wang D#, Hensman J, Kutkaite G, Toh TS, Galhoz A, GDSC Screening Team, Dry JR, Saez-Rodriguez J+, Garnett MJ, Menden MP#, Dondelinger F#
A statistical framework for assessing pharmacological responses and biomarkers using certainty estimates
eLife 2020

Inigo Ayestaran*, Ana Galhoz*, Elmar Spiegel, Ben Sidders, Jonathan R. Dry, Frank Dondelinger, Andreas Bender, Ultan McDermott, Francesco Iorio, Michael P. Menden#
Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens
Cell Patterns 2020 (IF: N/A, new Cell Journal)

 Guo T*#, Luna A*, Rajapakse VN*, ChiekKoh C*, Wu Z, Liu W, Sun Y, Gao H, Menden MP, Xu C, Calzone L, Martignetti L, Auwerx C, Buljan M, Banaei-Esfahani A, Ori A, Iskar M, Gillet L, Bi R, Zhang J, Zhang H, Yu C, Zhon Q, Varma S, Schmitt U, Qui P, Zhang Q, Zhu Y, Wild PJ, Garnett MJ, Bork P, Beck M, Liu K, Rodriguez JS, Elloumi F, Reinhold WC, Sander C, Pommier Y#, Aebersold R#
Quantitative proteome landscape of the NCI-60 cancer cell lines
iScience 2019

Menden MP*, Wang D*, Guan Y*, Mason M*, Szalai B*, Bulusu KC*, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang IS, Ghazoui Z, Ahsen MA, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Di Veroli G, Fawell S, Stolovitzky G, Guinney J#, Dry JR#, Saez-Rodriguez J#.
A cancer pharmacogenomic screen powering crowed-sourced advancement of drug combination prediction. 
Nature Communications 2019 (IF: 11.88)

Menden MP*, Casale FP*, Stephan J, Bignell GR, Iorio F, McDermott U, Garnett MJ, Saez-Rodriguez J#, Stegle O#.
The germline genetic component of drug sensitivity in cancer cell lines. 
Nature Communications 2018 (IF: 11.88)

Iorio F*, Knijnenburg TA*, Vis DJ*, Bignell GR*, Menden MP*, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Greninger P, van Dyk E, Chang H, de Silva H, Heyn HA, Deng X, Egan RK, Liu O, Mironenko T, Mitropoulos X, Richardson L, Wang J, Zhang T, Moran S, Saylos S, Soleimani M, Tamborero D, Lopez-Bigas N, Ross-Macdonald P, Esteller M, Gray N, Haber DA, Stratton MR, Benes CH, Wessels LFA, Saez-Rodriguez J, McDermott U#, Garnett MJ#.
A landscape of pharmacogenomic interactions in cancer.
Cell 2016 (IF: 28.71)

Stransky N*, Ghandi M*, Lehár J*, Amzallag A*, Menden MP*, Iorio F*, et al. (i.e. Cancer Cell Line Encyclopedia Consortium; Genomics of Drug Sensitivity in Cancer Consortium).
Pharmacogenomic agreement between two cancer cell line data sets.
Nature 2015 (IF: 41.46)
 

* equal contribution, # corresponding author, ' senior author.

FURTHER PUBLICATIONS: 
See google scholar for full list of publications