Scherm, M.G. ; Serr, I. ; Zahm, A.M. ; Schug, J. ; Bellusci, S. ; Manfredini, R. ; Salb, V.K. ; Gerlach, K. ; Weigmann, B. ; Ziegler, A.-G. ; Kaestner, K.H. ; Daniel, C.
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes.Vehik, K. ; Lynch, K.F. ; Wong, M.C. ; Tian, X. ; Ross, M.C. ; Gibbs, R.A. ; Ajami, N.J. ; Petrosino, J.F. ; Rewers, M. ; Toppari, J. ; Ziegler, A.-G. ; She, J.X. ; Lernmark, A. ; Akolkar, B. ; Hagopian, W.A. ; Schatz, D.A. ; Krischer, J.P. ; Hyöty, H. ; Lloyd, R.E.
Prospective virome analyses in young children at increased genetic risk for type 1 diabetes.Lindfors, K. ; Lin, J. ; Lee, H.S. ; Hyöty, H. ; Nykter, M. ; Kurppa, K. ; Liu, E. ; Koletzko, S. ; Rewers, M. ; Hagopian, W. ; Toppari, J. ; Ziegler, A.-G. ; Akolkar, B. ; Krischer, J.P. ; Petrosino, J.F. ; Lloyd, R.E. ; Agardh, D.
Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: The TEDDY study.Schäfer-Graf, U. ; Laubner, K. ; Hummel, S. ; Gembruch, U. ; Groten, T. ; Kainer, F. ; Grieshop, M. ; Bancher-Todesca, D. ; Cervar-Zivakovic, M. ; Hösli, I. ; Kaltheuner, M. ; Gellner, R. ; Kautzky-Willer, A. ; Bührer, C. ; Patchev, V. ; Nothacker, M.
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge. Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).Johnson, R.K. ; Vanderlinden, L. ; DeFelice, B.C. ; Kechris, K. ; Uusitalo, U. ; Fiehn, O. ; Sontag, M. ; Crume, T. ; Beyerlein, A. ; Lernmark, Å. ; Toppari, J. ; Ziegler, A.-G. ; She, J.X. ; Hagopian, W. ; Rewers, M. ; Akolkar, B. ; Krischer, J. ; Virtanen, S.M. ; Norris, J.M. ; Teddy Study Group
Metabolite-related dietary patterns and the development of islet autoimmunity.Gallegos, P.A. ; Balcacean, D. ; Zapardiel-Gonzalo, J. ; Richardson, S. ; Morgan, N. ; Akhbari, P. ; von Herrath, M. ; Kusmartseva, I. ; Pugliese, A. ; Rodriguez-Calvo, T.
Enterovirus as triggers of disease? New insights from autoantibody positive and type 1 diabetic nPOD donors.Van Rampelbergh, J. ; Boitard, C. ; Achenbach, P. ; Leslie, R.D. ; Dayan, C. ; Keymeulen, B. ; Owen, K.R. ; Lapauw, B. ; Carlier, V. ; Ahangarani, R.R. ; Gebruers, E. ; Vanderelst, L. ; Van Mechelen, M. ; Vandepapeliere, P.
Phase Ib clinical trial of IMCY-0098 in young adults with recent-onsent type 1 diabetes.Lampasona, V. ; Pittman, D.L. ; Williams, A.J. ; Achenbach, P. ; Schlosser, M. ; Akolkar, B. ; Winter, W.E.
Islet autoantibody standardization program 2018 workshop: Interlaboratory comparison of glutamic acid decarboxylase autoantibody assay performance.Roth, R. ; Lynch, K. ; Hyoty, H. ; Lönnrot, M. ; Driscoll, K.A. ; Johnson, S.B. ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Scholz, M. ; Stock, J. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
The association between stressful life events and respiratory infections during the first 4 years of life: The Environmental Determinants of Diabetes in the Young study.Andrén Aronsson, C. ; Lee, H.S. ; Hård Af Segerstad, E.M. ; Uusitalo, U. ; Yang, J. ; Koletzko, S. ; Liu, E. ; Kurppa, K. ; Bingley, P.J. ; Toppari, J. ; Ziegler, A.-G. ; She, J.X. ; Hagopian, W.A. ; Rewers, M. ; Akolkar, B. ; Krischer, J.P. ; Virtanen, S.M. ; Norris, J.M. ; Agardh, D.
Association of gluten intake during the first 5 years of Llfe with incidence of celiac disease autoimmunity and celiac disease among children at increased risk.Pigeot, I. ; Foraita, R. ; Frömke, C. ; Haller, B. ; Hoffmann, V. ; Zapf, A.
Ethical consideration of studies involving human subjects outside the regulatory framework: Not mandatory, but of high relevance (vol 62, pg 722, 2019).Uusitalo, U. ; Andrén Aronsson, C. ; Liu, X. ; Kurppa, K. ; Yang, J. ; Liu, E. ; Skidmore, J. ; Winkler, C. ; Rewers, M.J. ; Hagopian, W.A. ; She, J.X. ; Toppari, J. ; Ziegler, A.-G. ; Akolkar, B. ; Norris, J.M. ; Virtanen, S.M. ; Krischer, J.P. ; Agardh, D.
Early probiotic supplementation and the risk of celiac disease in children at genetic risk.Bonifacio, E. ; Achenbach, P.
Birth and coming of age of islet autoantibodies.Sebert, S. ; Lowry, E. ; Aumüller, N. ; Bermúdez, M.G. ; Bjerregaard, L.G. ; de Rooij, S.R. ; De Silva, M. ; El Marroun, H. ; Hummel, N. ; Juola, T. ; Mason, G. ; Much, D. ; Oliveros, E. ; Poupakis, S. ; Rautio, N. ; Schwarzfischer, P. ; Tzala, E. ; Uhl, O. ; van de Beek, C. ; Vehmeijer, F. ; Verdejo-Román, J. ; Wasenius, N. ; Webster, C. ; Ala-Mursula, L. ; Herzig, K.H. ; Keinänen-Kiukaanniemi, S. ; Miettunen, J. ; Baker, J.L. ; Campoy, C. ; Conti, G. ; Eriksson, J.G. ; Hummel, S. ; Jaddoe, V. ; Koletzko, B. ; Lewin, A. ; Rodriguez-Palermo, M. ; Roseboom, T. ; Rueda, R. ; Evans, J. ; Felix, J.F. ; Prokopenko, I. ; Sørensen, T.I.A. ; Järvelin, M.R.
Cohort Profile: The DynaHEALTH consortium - a European consortium for a life-course bio-psychosocial model of healthy ageing of glucose homeostasis.Hoffmann, V. ; Weiß, A. ; Winkler, C. ; Knopff, A. ; Jolink, M. ; Bonifacio, E. ; Ziegler, A.-G.
Landmark models to define the age-adjusted risk of developing stage 1 type 1 diabetes across childhood and adolescence.Ziegler, A.-G. ; Achenbach, P. ; Berner, R. ; Casteels, K. ; Danne, T. ; Gündert, M. ; Hasford, J. ; Hoffmann, V. ; Kordonouri, O. ; Lange, K. ; Elding Larsson, H. ; Lundgren, M. ; Snape, M.D. ; Szypowska, A. ; Todd, J.A. ; Bonifacio, E. ; The GPPAD Study
Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol.Winkler, C. ; Jolink, M. ; Knopff, A. ; Kwarteng, N.-A. ; Achenbach, P. ; Bonifacio, E. ; Ziegler, A.-G.
Age, HLA, and sex define a marked risk of organ-specific autoimmunity in first-degree relatives of patients with type 1 diabetes.Winkler, C. ; Haupt, F. ; Heigermoser, M. ; Zapardiel-Gonzalo, J. ; Ohli, J. ; Faure, T. ; Kalideri, E. ; Hommel, A. ; Delivani, P. ; Berner, R. ; Kordonouri, O. ; Roloff, F. ; von dem Berge, T. ; Lange, K. ; Oltarzewski, M. ; Glab, R. ; Szypowska, A. ; Snape, M.D. ; Vatish, M. ; Todd, J.A. ; Larsson, H.E. ; Ramelius, A. ; Kördel, J. ; Casteels, K. ; Paulus, J. ; Ziegler, A.-G. ; Bonifacio, E.
Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results.Schäfer-Graf, U. ; Laubner, K. ; Hummel, S. ; Gembruch, U. ; Groten, T. ; Kainer, F. ; Grieshop, M. ; Bancher-Todesca, D. ; Cervar-Zivakovic, M. ; Hösli, I. ; Kaltheuner, M. ; Gellner, R. ; Kautzky-Willer, A. ; Bührer, C. ; Patchev, V. ; Nothacker, M.
Gestational Diabetes mellitus (GDM), Diagnostics, Therapy and Aftercare Practice Recommendation - Abstract of the S3 Guideline (AWMF Register Number: 057-008).Krischer, J.P. ; Liu, X. ; Vehik, K. ; Akolkar, B. ; Hagopian, W.A. ; Rewers, M.J. ; She, J.X. ; Toppari, J. ; Ziegler, A.-G. ; Lernmark, A. ; The Teddy Study Group
Predicting islet cell autoimmunity and type 1 diabetes: An 8-year TEDDY study progress report.Kick, K. ; Achenbach, P.
Infektionen in der Schwangerschaft und frühen Kindheit. Risiko für Betazell-Autoimmunität und Typ-1-Diabetes?Pigeot, I. ; Foraita, R. ; Frömke, C. ; Haller, B. ; Hoffmann, V. ; Zapf, A.
Ethical consideration of studies involving human subjects outside the regulatory framework: not mandatory, but of high relevance.Laimighofer, M. ; Lickert, R. ; Fuerst, R. ; Theis, F.J. ; Winkler, C. ; Bonifacio, E. ; Ziegler, A.-G. ; Krumsiek, J.
Common patterns of gene regulation associated with Cesarean section and the development of islet autoimmunity - indications of immune cell activation.Eugster, A. ; Kraus, G. ; Lidzba, V. ; Müller, D. ; Jolink, M. ; Ziegler, A.-G. ; Bonifacio, E.
Cytoplasmic ends of tetraspanin 7 harbour epitopes recognised by autoantibodies in type 1 diabetes.Ashton, M.P. ; Eugster, A. ; Dietz, S. ; Loebel, D. ; Lindner, A. ; Kuehn, D. ; Taranko, A.E. ; Heschel, B. ; Gavrisan, A. ; Ziegler, A.-G. ; Aringer, M. ; Bonifacio, E.
Association of dendritic cell signatures with autoimmune inflammation revealed by single-cell profiling.Winkler, C.
Infantile vitamin-D-levels determine the risk for type 1-diabetes.Jacobsen, L.M. ; Elding Larsson, H. ; Tamura, R.N. ; Vehik, K. ; Clasen, J. ; Sosenko, J.M. ; Hagopian, W.A. ; She, J.X. ; Steck, A.K. ; Rewers, M. ; Simell, O. ; Toppari, J. ; Veijola, R. ; Ziegler, A.-G. ; Krischer, J.P. ; Akolkar, B. ; Haller, M.J. ; The Teddy Study Group
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.Hippich, M. ; Beyerlein, A. ; Hagopian, W.A. ; Krischer, J.P. ; Vehik, K. ; Knoop, J. ; Winker, C. ; Toppari, J. ; Lernmark, Å. ; Rewers, M.J. ; Steck, A.K. ; She, J.X. ; Akolkar, B. ; Robertson, C.C. ; Onengut-Gumuscu, S. ; Rich, S.S. ; Bonifacio, E. ; Ziegler, A.-G. ; The Teddy Study Group
Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families.Ziegler, A.-G. ; Hoffmann, G.F. ; Hasford, J. ; Larsson, H.E. ; Danne, T. ; Berner, R. ; Penno, M. ; Koralova, A. ; Dunne, J. ; Bonifacio, E.
Screening for asymptomatic β-cell autoimmunity in young children.Silvis, K. ; Aronsson, C.A. ; Liu, X. ; Uusitalo, U. ; Yang, J. ; Tamura, R. ; Lernmark, A. ; Rewers, M. ; Hagopian, W. ; She, J.X. ; Simell, O. ; Toppari, J. ; Ziegler, A.-G. ; Akolkar, B. ; Krischer, J. ; Virtanen, S.M. ; Norris, J.M. ; Teddy Study Group
Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study.Peplow, C. ; Assfalg, R. ; Beyerlein, A. ; Hasford, J. ; Bonifacio, E. ; Ziegler, A.-G.
Blood draws up to 3% of blood volume in clinical trials are safe in children.Ungethüm, K. ; Jolink, M. ; Hippich, M. ; Lachmann, L. ; Haupt, F. ; Winkler, C. ; Hummel, S. ; Pitchika, A. ; Kordonouri, O. ; Ziegler, A.-G. ; Beyerlein, A.
Physical activity is associated with lower insulin and C-peptide during glucose challenge in children and adolescents with family background of diabetes.