Hummel, S. ; Ott, R.
Maternal type 1 diabetes might protect offspring through epigenetic modifications.Mathieu, C. ; Wych, J. ; Hendriks, A.E.J. ; Van Ryckeghem, L. ; Tree, T. ; Chmura, P. ; Möller, C. ; Casteels, K. ; Danne, T. ; Reschke, F. ; Šmigoc Schweiger, D. ; Battelino, T. ; Johannesen, J. ; Rami-Merhar, B. ; Pieber, T. ; De Block, C. ; Evans, M. ; Hilbrands, R. ; Bosi, E. ; Willemsen, R.H. ; Basu, S. ; Pulkkinen, M.A. ; Knip, M. ; Cnop, M. ; Nitsche, A. ; Schulte, A.M. ; Niemöller, E. ; Peakman, M. ; Wilhelm-Benartzi, C. ; Gillespie, D. ; Overbergh, L. ; Mander, A.P. ; Marcovecchio, M.L. ; INNODIA consortium (Ziegler, A.-G.)
Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): A phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.Vercauteren, J. ; EDENT1FI consortium (Ziegler, A.-G.) ; EDENT1FI consortium (Achenbach, P.) ; EDENT1FI consortium (Winkler, C.) ; EDENT1FI consortium (Hummel, S.) ; EDENT1FI consortium (Korhonova, K.) ; EDENT1FI consortium (Scholz, M.) ; EDENT1FI consortium (Owoeye, S.) ; EDENT1FI consortium (Gündert, M.) ; EDENT1FI consortium (Kohls, M.) ; EDENT1FI consortium (Hoffmann, L.)
Harmonising terminology for type 1 diabetes: The EDENT1FI lexicon initiative.Rodriguez-Calvo, T.
Typ-1-Diabetes Merkmale unter dem Mikroskop. Ernst-Friedrich-Pfeiffer-Preis 2025 – Kurzübersicht der Preisträgerin Teresa Rodriguez-Calvo.Landgraf, R. ; Heinemann, L. ; Schwarz, T. ; Niederau, C. ; Pleus, S. ; Tytko, A. ; Werner, C. ; Müller-Wieland, D. ; Müller, U.A. ; Freckmann, G. ; Schleicher, E. ; Ziegler, A.-G. ; Nauck, M. ; Petersmann, A.
Definition, Klassifikation, Diagnostik und Differenzialdiagnostik des Diabetes mellitus: Update 2025.Schäfer-Graf, U.M. ; Laubner, K. ; Hummel, S. ; Gembruch, U. ; Groten, T. ; Kainer, F. ; Grieshop, M. ; Bancher-Todesca, D. ; Cervar-Zivkovic, M. ; Hösli, I. ; Kaltheuner, M. ; Gellner, R. ; Kautzky-Willer, A. ; Bührer, C. ; Hummel, M.
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge.Skurk, T. ; Grünerbel, A. ; Hummel, S. ; Kabisch, S. ; Keuthage, W. ; Kleinridders, A. ; Müssig, K. ; Nussbaumer, H. ; Rubin, D. ; Simon, M. ; Tombek, A. ; Weber, K.S.C.
Recommendations for the dietary prevention of type 2 diabetes mellitus.Weiss, A. ; Chakievska, L. ; Achenbach, P. ; Hergl, M. ; Hummel, S. ; Ott, R. ; Scholz, M. ; Winkler, C. ; Bonifacio, E. ; Ziegler, A.-G.
Stratifying the rate of disease progression by Progression Likelihood Scores in children and adolescents with stage 1 and stage 2 type 1 diabetes in Germany.Couper, J.J. ; Oakey, H. ; Penno, M.A.S. ; Wentworth, J.M. ; Watson, K.A. ; Brown, J.D. ; Huynh, D. ; Thomson, R.L. ; Craig, M.E. ; Davis, E.A. ; Haynes, A. ; Huynh, T.T. ; Vuillermin, P.J. ; Soldatos, G. ; Lopez, P.E. ; Morahan, G. ; McGorm, K. ; Kim, K.W. ; Barry, S.J. ; Hamilton-Williams, E.E. ; Rawlinson, W.D. ; Sinnott, R. ; Harrison, L.C. ; Achenbach, P. ; Colman, P.G.
Evolution of islet autoantibodies in the Environmental Determinants of Islet Autoimmunity (ENDIA) prospective cohort.Veijola, R. ; Tamura, R.N. ; Clasen, J.L. ; Elding Larsson, H. ; Warncke, K. ; Steck, A.K. ; Haller, M.J. ; Jonsdottir, B. ; Akolkar, B. ; Hagopian, W.A. ; Rewers, M.J. ; She, J.X. ; Ziegler, A.-G. ; Krischer, J.P. ; Toppari, J.
Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.Ziegler, A.-G. ; Achenbach, P. ; Weiss, A. ; Berner, R. ; Casteels, K. ; Larsson, H.E. ; Haupt, F. ; Hommel, A. ; Jacobs, A. ; Kordonouri, O. ; Lundgren, M. ; Ołtarzewski, M. ; Pfirrmann, M. ; Snape, M.D. ; Szypowska, A. ; Todd, J.A. ; Vatish, M. ; Berge, T.V.D. ; Winkler, C. ; Bonifacio, E.
Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): A European, randomised, placebo-controlled, primary prevention trial.Ott, R. ; Zapardiel-Gonzalo, J. ; Kreitmaier, P. ; Casteels, K. ; Hommel, A. ; Kordonouri, O. ; Elding Larsson, H. ; Szypowska, A. ; Vatish, M. ; Zeggini, E. ; Knopff, A. ; Winkler, C. ; Ziegler, A.-G. ; Bonifacio, E. ; Hummel, S.
Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity.Ott, R. ; Singh, T. ; Schütte-Borkovec,K. ; Scholz, M. ; Casteels, K. ; Gemulla, G. ; Kordonouri, O. ; Elding Larsson, H. ; Szypowska, A. ; Todd, J.A. ; Ziegler, A.-G. ; Bonifacio, E.
Epigenetic differences at immune and type 1 diabetes susceptibility genes in blood from young children after COVID-19 infection.Gehmeyr, M. ; Rojas López, M.B. ; Nitkunanantharajah, S. ; Preissl, H. ; Vosseler, A. ; Jumpertz von Schwartzenberg, R. ; Birkenfeld, A.L. ; Katsouli, N. ; Fasoula, N.-A. ; Karlas, A. ; Kallmayer, M. ; Ziegler, A.-G. ; Jüstel, D. ; Ntziachristos, V.
Enhanced maximum intensity projection (eMIP) for improving the fidelity of optoacoustic images.You, L. ; Salami, F. ; Tamura, R. ; Törn, C. ; Vehik, K. ; Hagopian, W.A. ; Rewers, M.J. ; McIndoe, R.A. ; Toppari, J. ; Ziegler, A.-G. ; Akolkar, B. ; Krischer, J.P. ; Lernmark, Å.
Predictors of transitions from GADA as the initial autoantibody to multiple autoantibodies of type 1 diabetes in children at risk by a dynamic prediction model.Köger, M. ; Winkler, C. ; Hummel, S. ; Weiss, A. ; Koutangni, T. ; Yates, M. ; Bonnemaire, M. ; Guenther, O. ; Zaccai, J. ; Ziegler, A.-G.
Generalizability of progression risk in the TN-10 trial to a European population with or without a first-degree relative with type 1 diabetes.Ziegler, A.-G. ; Cengiz, E. ; Kay, T.W.H.
The future of type 1 diabetes therapy.Koskenniemi, J.J. ; Clasen, J.L. ; You, L. ; Parikh, H.M. ; Vehik, K. ; Yang, J. ; Uusitalo, U. ; Veijola, R. ; Haller, M.J. ; Ziegler, A.-G. ; Rewers, M.J. ; Hagopian, W.A. ; Akolkar, B. ; Lernmark, A. ; Toppari, J. ; Larsson, H.E. ; Krischer, J.P. ; Lynch, K.F. ; Germany clinical center (Sanverdi, C. ; Heublein, A. ; Hummel, S. ; Knopff, A. ; Köger, M. ; Koletzko, S. ; Ramminger, C. ; Roth, R. ; Schmidt, J. ; Scholz, M. ; Stock, J. ; Warncke, K. ; Müller, L. ; Winkler, C.)
The contribution of BMI to a young child's risk of islet autoimmunity is dependent on HLA-DR4-DQ8 without HLA-DR3-DQ2.Skurk, T. ; Grünerbel, A. ; Hummel, S. ; Kabisch, S. ; Keuthage, W. ; Müssig, K. ; Nussbaumer, H. ; Rubin, D. ; Simon, M.C. ; Tombek, A. ; Weber, K.S.C.
Empfehlungen zurErnährungsprävention des Typ-2-Diabetes mellitus.von dem Berge, T. ; Achenbach, P. ; Gemulla, G. ; Hummel, S. ; Loff, A. ; Kordonouri, O.
Früherkennung des Typ-1-Diabetes im Kindesalter.Das Fr1da-plex-Netzwerk in Deutschland.Schäfer-Graf, U.M. ; Laubner, K. ; Hummel, S. ; Gembruch, U. ; Groten, T. ; Kainer, F. ; Grieshop, M. ; Bancher-Todesca, D. ; Cervar-Zivkovic, M. ; Hösli, I. ; Kaltheuner, M. ; Gellner, R. ; Kautzky-Willer, A. ; Bührer, C. ; Hummel, M.
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und NachsorgeKurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).Schäfer-Graf, U.M. ; Laubner, K. ; Hummel, S. ; Gembruch, U. ; Groten, T. ; Kainer, F. ; Grieshop, M. ; Bancher-Todesca, D. ; Cervar-Zivkovic, M. ; Hösli, I. ; Kaltheuner, M. ; Gellner, R. ; Kautzky-Willer, A. ; Bührer, C. ; Hummel, M.
Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care.Zapardiel-Gonzalo, J. ; Ziegler, A.-G. ; Bonifacio, E.
The genetic architecture of type 1 diabetes over time: How well can we rely on past data to predict the future?Tutino, M. ; Yu, N.Y.-L. ; Hatzikotoulas, K. ; Park, Y.-C. ; Kreitmaier, P. ; Katsoula, G. ; Berner, R. ; Casteels, K. ; Elding Larsson, H. ; Kordonouri, O. ; Ołtarzewski, M. ; Szypowska, A. ; Ott, R. ; Weiss, A. ; Winkler, C. ; Zapardiel-Gonzalo, J. ; Petrera, A. ; Hauck, S.M. ; Bonifacio, E. ; Ziegler, A.-G. ; Zeggini, E.
Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes.Rewers, M. ; Agardh, D. ; Johnson, S.B. ; Bonifacio, E. ; Larsson, H.E. ; Gesualdo, P. ; Hagopian, W. ; Haller, M.J. ; Hyöty, H. ; Johnson, R. ; McIndoe, R. ; McKinney, E.F. ; Melin, J. ; Lernmark, Å. ; Lloyd, R.E. ; Lynch, K.F. ; Norris, J.M. ; Rich, S.S. ; Roth, R. ; Schatz, D. ; Toppari, J. ; Triplett, E.W. ; Vehik, K. ; Virtanen, S.M. ; Ziegler, A.-G. ; Akolkar, B. ; Krischer, J.P.
Unfolding the mystery of autoimmunity: The environmental determinants of diabetes in the young (TEDDY) study.Helmholtz Health Prevention Task Force (Peters, A.) ; Hamann, S. ; Leendertz, F.H. ; Lange, B. ; Guzman, C.A. ; Grün, B. ; Jewell, S. ; Breteler, M.M.B. ; Aziz, N.A. ; Schiattarella, G.G. ; Lee, Y.A. ; Landthaler, M. ; Gorski, S.A. ; Steindorf, K. ; Hoffmeister, M. ; Braun, A. ; Helmholtz Health Prevention Task Force (Ziegler, A.-G.) ; Helmholtz Health Prevention Task Force (von Mutius, E.) ; Helmholtz Health Prevention Task Force (Krüger, J.) ; Mons, U. ; Helmholtz Health Prevention Task Force (Zeggini, E.)
Helmholtz Health task force to strengthen prevention research and its translation globally.Bonifacio, E. ; Coelho, R. ; Ewald, D.A. ; Gemulla, G. ; Hubmann, M. ; Jarosz-Chobot, P. ; Kohls, M. ; Kordonouri, O. ; Lampasona, V. ; Narendran, P. ; Pociot, F. ; Šumník, Z. ; Szypowska, A. ; Zapardiel-Gonzalo, J. ; Ziegler, A.-G.
The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes.Zeller, I. ; Weiss, A. ; Hummel, S. ; Ziegler, A.-G. ; Bonifacio, E.
Age-dependent gene expression trajectories during early childhood in children at increased risk for type 1 diabetes.Becker, M. ; Kälin, S. ; Neubig, A.H. ; Lauber, M. ; Opaleva, D. ; Hipp, H. ; Salb, V.K. ; Ott, V. ; Legutko, B. ; Kälin, R.E. ; Hippich, M. ; Scherm, M.G. ; Nascimento, L.F.R. ; Serr, I. ; Hosp, F. ; Nikolaev, A. ; Mohebiany, A. ; Krueger, M. ; Flachmeyer, B. ; Pfaffl, M.W. ; Haase, B. ; Yi, C.X. ; Dietzen, S. ; Bopp, T. ; Woods, S.C. ; Waisman, A. ; Weigmann, B. ; Mann, M. ; Tschöp, M.H. ; Daniel, C.
Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments.Warncke, K. ; Hofer, S.E. ; von Sengbusch, S. ; Ermer, U. ; Niemeyer, M. ; Lemmer, A. ; Hilgard, D. ; Welters, A. ; Holl, R.W. ; Eckert, A.J.
Did smoking behavior change in adolescents and young adults with and without diabetes during the COVID-19 pandemic? A cohort study from the DPV registry.Bonifacio, E. ; Ziegler, A.-G.
Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening.Hård Af Segerstad, E.M. ; Mramba, L.K. ; Aronsson, C.A. ; Uusitalo, U. ; Virtanen, S.M. ; Agardh, D. ; TEDDY Study Group (Ziegler, A.-G.)
Early dietary fiber intake reduces celiac disease risk in genetically prone children: Insights from the TEDDY study.Rodriguez-Calvo, T. ; Laiho, J.E. ; Oikarinen, M. ; Akhbari, P. ; Flaxman, C. ; Worthington, T. ; Apaolaza Gallegos, S.P. ; Kaddis, J.S. ; Kusmartseva, I. ; Tauriainen, S. ; Campbell-Thompson, M. ; Atkinson, M.A. ; von Herrath, M. ; Hyöty, H. ; Morgan, N.G. ; Pugliese, A. ; Richardson, S.J.
Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes.Richardson, S.J. ; Rodriguez-Calvo, T. ; Laiho, J.E. ; Kaddis, J.S. ; Nyalwidhe, J.O. ; Kusmartseva, I. ; Morfopoulou, S. ; Petrosino, J.F. ; Plagnol, V. ; Maedler, K. ; Morris, M.A. ; Nadler, J.L. ; Atkinson, M.A. ; von Herrath, M. ; Lloyd, R.E. ; Hyöty, H. ; Morgan, N.G. ; Pugliese, A.
Joint analysis of the nPOD-Virus Group data: The association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue.Krischer, J.P. ; Muller, S. ; You, L. ; Achenbach, P. ; Bazzigaluppi, E. ; Brigatti, C. ; Lampasona, V. ; Mathew, A. ; Robinson, P.N. ; Seftel, D. ; Sigal, G. ; Tsai, C.T. ; Wang, M. ; Yu, L.
A comparative analysis of the sensitivity, specificity, concordance, and the 5-year predictive power of diabetes-related autoantibody assays.Gesualdo, P. ; Melin, J. ; Karban, R. ; Crouch, C. ; Killian, M. ; Hopkins, D. ; Adamsson, A. ; Stock, J. ; Johnson, S.B. ; Baxter, J. ; Germany clinical center (Ziegler, A.-G. ; Sanverdi, C. ; Heublein, A. ; Hummel, S. ; Grätz, W. ; Knopff, A. ; Köger, M. ; Koletzko, S. ; Ramminger, C. ; Roth, R. ; Schmidt, J. ; Scholz, M. ; Warncke, K. ; Winkler, C. ; Müller, L.)
Structures and strategies for retaining an international pediatric cohort from birth: Lessons from The Environmental Determinants of Diabetes in the Young (TEDDY) study.Phillip, M. ; Achenbach, P. ; Addala, A. ; Albanese-O'Neill, A. ; Battelino, T. ; Bell, K.J. ; Besser, R.E.J. ; Bonifacio, E. ; Colhoun, H.M. ; Couper, J.J. ; Craig, M.E. ; Danne, T. ; de Beaufort, C. ; Dovc, K. ; Dutta, S. ; Ebekozien, O. ; Elding Larsson, H. ; Frohnert, B.I. ; Gallagher, M.P. ; Greenbaum, C.J. ; Griffin, K.J. ; Hagopian, W. ; Haller, M.J. ; Hendriks, E. ; Holt, R.I.G. ; Ismail, H.M. ; Jacobsen, L.M. ; Kolb, L.E. ; Kordonouri, O. ; Lange, K. ; Lash, R.W. ; Lernmark, Å. ; Libman, I.M. ; Lundgren, M. ; Maahs, D.M. ; Marcovecchio, M.L. ; Mathieu, C. ; Oron, T. ; Patil, S.P. ; Rewers, M.J. ; Rich, S.S. ; Schatz, D.A. ; Schulman-Rosenbaum, R. ; Simmons, K.M. ; Sims, E.K. ; Skyler, J.S. ; Speake, C. ; Steck, A.K. ; Tonyushkina, K.N. ; Veijola, R. ; Wentworth, J.M. ; Wherrett, D.K. ; Wood, J.R. ; Ziegler, A.-G. ; Dimeglio, L.A.
Considerations for more actionable consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Reply to Mallone R [letter].Hummel, S. ; Käßl, A. ; Arnolds, S. ; Achenbach, P. ; Berner, R. ; Casteels, K. ; Hyöty, H. ; Kordonouri, O. ; Larsson, H.E. ; Lundgren, M. ; Marcovecchio, M.L. ; Owen, C. ; Pfirrmann, M. ; Robson, S.C. ; Szadkowska, A. ; Szypowska, A. ; Tree, T. ; Weiss, A. ; Ziegler, A.-G. ; Bonifacio, E.
Anti-viral action against type 1 diabetes autoimmunity: The GPPAD-AVAnT1A study protocol.Schwarz, T. ; Niederau, C. ; Pleus, S. ; Tytko, A. ; Landgraf, R. ; Werner, C. ; Mueller-Wieland, D. ; Mueller, U.A. ; Freckmann, G. ; Schleicher, E. ; Nauck, M. ; Petersmann, A. ; Ziegler, A.-G. ; Heinemann, L.
Definition, Klassifikation, Diagnostik und Differenzialdiagnostik des Diabetes mellitus: Update 2024.Hoffmann, L. ; Kohls, M. ; Arnolds, S. ; Achenbach, P. ; Bergholdt, R. ; Bonifacio, E. ; Bosi, E. ; Gündert, M. ; Höfelschweiger, B.K. ; Hummel, S. ; Jarosz-Chobot, P. ; Kordonouri, O. ; Lampasona, V. ; Narendran, P. ; Overbergh, L. ; Pociot, F. ; Raposo, J.F. ; Šumník, Z. ; Szypowska, A. ; Vercauteren, J. ; Winkler, C. ; Mathieu, C. ; Ziegler, A.-G.
EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents.Hummel, S. ; Köger, M. ; Bonifacio, E. ; Ziegler, A.-G.
Dysglycaemia definitions and progression to clinical type 1 diabetes in children with multiple islet autoantibodies.