Publications
Publications
Friedmann Angeli, J.P.F. ; Proneth, B. ; Hammond, V.J. ; Tyurina, Y.Y. ; Tyurin, V.A. ; O'Donnell, V.B. ; Kagan, V.E. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in a therapeutically relevant mechanism.Götz, S.
Die Rolle des Wnt/ß-Catenin-Signalweges bei der Entwicklung meso-diencephalisch dopaminerger Neuronen.Karaca, E.
Role of Sp transcription factors in adult neurogenesis.Aprile-Garcia, F. ; Metzger, M.W. ; Dedic, N. ; Walser, S.M. ; Jakubcakova, V. ; Czamara, D. ; Mitkovski, M. ; Müller-Myhsok, B. ; Kimura, M. ; Wurst, W. ; Stuehmer, W. ; Holsboer, F. ; Arzt, E. ; Deussing, J.M.
P2RX7-a susceptibility gene for mood disorders?Matsui, H. ; Namikawa, K. ; Köster, R.W.
Identification of the zebrafish red nucleus using wheat germ agglutinin transneuronal tracing.Meier, F.
Signaling pathways in mesodiencephalic dopaminergic and cerebellar neural development in vitro and in vivo.Panda, S.
Establishment of mouse disease models by using sequence specific nucleases.Häberle, M.-T. ; Kelsch, E. ; Dorsch, K. ; Möller, P. ; Ritz, O.
Knock-down of BCL6 / STAT6 sensitizes primary B cell lymphoma cells for treatment with current therapeutic agents.Andjeli, S. ; Lumi, X. ; Yan, X. ; Graw, J. ; Moe, M.C. ; Facskó, A. ; Hawlina, M. ; Petrovski, G.
Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes.Becker, L. ; Kling, E. ; Schiller, E. ; Zeh, R. ; Schrewe, A. ; Hölter, S.M. ; Mossbrugger, I. ; Calzada-Wack, J. ; Strecker, V. ; Wittig, I. ; Dumitru, I. ; Wenz, T. ; Bender, A. ; Aichler, M. ; Janik, D. ; Neff, F. ; Walch, A.K. ; Quintanilla-Fend, L. ; Floß, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Meitinger, T. ; Prokisch, H. ; Hrabě de Angelis, M. ; Klopstock, T.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Schäffner, I.
Fox transcription factors in adult neurogenesis.Brockmann, M.
Nedd8 in the brain - Its impact on synaptic function and the role of PSD-95.Symvoulidis, P. ; Cruz Perez, C. ; Schwaiger, M. ; Ntziachristos, V. ; Westmeyer, G.G.
Serial sectioning and mulstispectral imaging system for versatile biomedical applications.Gewies, A. ; Gorka, O. ; Bergmann, H. ; Pechloff, K. ; Petermann, F. ; Jeltsch, K. ; Rudelius, M. ; Kriegsmann, M. ; Weichert, W. ; Horsch, M. ; Beckers, J. ; Wurst, W. ; Heikenwälder, M. ; Korn, T. ; Heissmeyer, V. ; Ruland, J.
Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation.Giusti, S.A. ; Vogl, A.M. ; Brockmann, M.M. ; Vercelli, C.A. ; Rein, M.L. ; Trümbach, D. ; Wurst, W. ; Cazalla, D. ; Stein, V. ; Deussing, J.M. ; Refojo, D.
MicroRNA-9 controls dendritic development by targeting REST.Friedmann Angeli, J.P.F. ; Schneider, M. ; Proneth, B. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Hammond, V.J. ; Herbach, N. ; Aichler, M. ; Walch, A.K. ; Eggenhofer, E. ; Basavarajappa, D. ; Rådmark, O. ; Kobayashi, S. ; Seibt, T. ; Beck, H. ; Neff, F. ; Esposito, I. ; Wanke, R. ; Förster, H. ; Yefremova, O. ; Heinrichmeyer, M. ; Bornkamm, G.W. ; Geissler, E.K. ; Thomas, S.B. ; Stockwell, B.R. ; O'Donnell, V.B. ; Kagan, V.E. ; Schick, J. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Ramin, M. ; Bürger, A. ; Hörlein, A. ; Kerkau, D. ; von Walcke-Wulffen, V. ; Nicklas, W. ; Schenkel, J.
Stability of cryopreserved samples of mutant mice.Thor, T. ; Künkele, A. ; Pajtler, K.W. ; Wefers, A.K. ; Stephan, H. ; Mestdagh, P. ; Heukamp, L. ; Hartmann, W. ; Vandesompele, J. ; Sadowski, N. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Horsch, M. ; Calzada-Wack, J. ; Klein-Rodewald, T. ; Rácz, I. ; Zimmer, A. ; Beckers, J. ; Neff, F. ; Klopstock, T. ; de Antonellis, P. ; Zollo, M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Schüller, U. ; Hrabě de Angelis, M. ; Eggert, A. ; Schramm, A. ; Schulte, J.H.
MiR-34a deficiency accelerates medulloblastoma formation in vivo.Wefers, B. ; Ortiz, O. ; Wurst, W. ; Kühn, R.
Generation of targeted mouse mutants by embryo microinjection of TALENs.Sotnikov, S.V. ; Chekmareva, N.Y. ; Schmid, B. ; Harbich, D. ; Malik, V. ; Bauer, S. ; Kuehne, C. ; Markt, P.O. ; Deussing, J.M. ; Schmidt, M.V. ; Landgraf, R.
Enriched environment impacts trimethylthiazoline-induced anxiety-related behavior and immediate early gene expression: Critical role of Crhr1.Kühn, R. ; Wefers, B.
Editing and investigating genomes with TALE and CRISPR/Cas systems: Genome engineering across species using TALENs.Kühn, R. ; Brandl, C. ; Ortiz, O. ; Wurst, W.
Generation of targeted deletions in mouse zygotes by pairs of TALENs or SGRNAS/Cas9.Tiedemann, H.B. ; Schneltzer, E. ; Zeiser, S. ; Wurst, W. ; Beckers, J. ; Przemeck, G.K.H. ; Hrabě de Angelis, M.
Fast synchronization of ultradian oscillators controlled by Delta-Notch signaling with Cis-inhibition.Kandasamy, M. ; Lehner, B. ; Kraus, S. ; Sander, P.R. ; Marschallinger, J. ; Rivera, F.J. ; Trümbach, D. ; Ueberham, U. ; Reitsamer, H.A. ; Strauss, O. ; Bogdahn, U. ; Couillard-Despres, S. ; Aigner, L.
TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons.Schötz, U. ; Deliolanis, N. ; Ng, D. ; Pauli, J. ; Resch-Genger, U. ; Kühn, E. ; Heuer, S. ; Beisker, W. ; Köster, R.W. ; Zitzelsberger, H. ; Caldwell, R.B.
Usefulness of a darwinian system in a biotechnological application: Evolution of optical window fluorescent protein variants under selective pressure.Matthes, M. ; Preusse, M. ; Zhang, J. ; Schechter, J. ; Mayer, D. ; Lentes, B. ; Theis, F.J. ; Prakash, N. ; Wurst, W. ; Trümbach, D.
Mouse IDGenes: A reference database for genetic interactions in the developing mouse brain.Nehls, J. ; Koppensteiner, H. ; Brack-Werner, R. ; Floß, T. ; Schindler, M.
HIV-1 replication in human immune cells is independent of TAR DNA binding Protein 43 (TDP-43) expression.Kraus, P. ; Sivakamasundari, V. ; Yu, H.B. ; Xing, X. ; Lim, S.L. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Janas, E. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Adamski, J. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Eickelberg, O. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Lufkin, T. ; Stanton, L.W.
Pleiotropic functions for transcription factor Zscan10.Kemter, E. ; Rathkolb, B. ; Becker, L. ; Bolle, I. ; Busch, D.H. ; Dalke, C. ; Elvert, R. ; Favor, J. ; Graw, J. ; Hans, W. ; Ivandic, B. ; Kaladydjiev, S. ; Klopstock, T. ; Rácz, I. ; Rozman, J. ; Schrewe, A. ; Schulz, H. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wolf, E. ; Aigner, B.
Standardized, systemic phenotypic analysis of Slc12a1 I299F mutant mice.Floß, T.
Reply to Jawaid et al.: Mitochondrial dysfunction and decrease in body weight of transgenic knock-in mouse model for TDP-43: The question of glucose?.Blanco, S. ; Dietmann, S. ; Flores, J.V. ; Hussain, S. ; Kutter, C. ; Humphreys, P. ; Lukk, M. ; Lombard, P. ; Treps, L. ; Popis, M. ; Kellner, S. ; Hölter, S.M. ; Garrett, L. ; Wurst, W. ; Becker, L. ; Klopstock, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Káradóttir, R.T. ; Helm, M. ; Ule, J. ; Gleeson, J.G. ; Odom, D.T. ; Frye, M.
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.Toyoda, Y. ; Erkut, C. ; Pan-Montojo, F. ; Boland, S. ; Stewart, M.P. ; Müller, D.J. ; Wurst, W. ; Hyman, A.A. ; Kurzchalia, T.V.
Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival.Matsui, H. ; Namikawa, K. ; Babaryka, A. ; Köster, R.W.
Functional regionalization of the teleost cerebellum analyzed in vivo.Sotnikov, S. ; Wittmann, A. ; Bunck, M. ; Bauer, S. ; Deussing, J.M. ; Schmidt, M. ; Touma, C. ; Landgraf, R. ; Czibere, L.
Blunted HPA axis reactivity reveals glucocorticoid system dysbalance in a mouse model of high anxiety-related behavior.Meier, F. ; Giesert, F. ; Delic, S. ; Faus-Kessler, T. ; Matheus, F. ; Simeone, A. ; Hölter, S.M. ; Kühn, R. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Prakash, N.
FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.Lewerenz, J. ; Baxter, P.S. ; Kassubek, R. ; Albrecht, P. ; van Liefferinge, J. ; Westhoff, M.A. ; Halatsch, M.E. ; Karpel-Massler, G. ; Meakin, P.J. ; Hayes, J.D. ; Aronica, E.M. ; Smolders, I. ; Ludolph, A.C. ; Methner, A. ; Conrad, M. ; Massie, A. ; Hardingham, G.E. ; Maher, P.A.
Phosphoinositide 3-kinases upregulate system xc - via eukaryotic initiation factor 2α and activating transcription factor 4-A pathway active in glioblastomas and epilepsy.Marzaioli, V. ; Aguilar-Pimentel, J.A. ; Weichenmeier, I. ; Luxenhofer, G. ; Wiemann, M. ; Landsiedel, R. ; Wohlleben, W. ; Eiden, S. ; Mempel, M. ; Behrendt, H. ; Schmidt-Weber, C.B. ; Gutermuth, J. ; Alessandrini, F.
Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties.Zumbrennen-Bullough, K.B. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Calzada-Wack, J. ; Mossbrugger, I. ; Quintanilla-Fend, L. ; Rácz, I. ; Rathkolb, B. ; Klopstock, T. ; Wurst, W. ; Zimmer, A. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Romney, S.J. ; Leibold, E.A.
Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments.Yan, X. ; Sabrautzki, S. ; Horsch, M. ; Fuchs, H. ; Gailus-Durner, V. ; Beckers, J. ; Hrabě de Angelis, M. ; Graw, J.
Peroxidasin is essential for eye development in the mouse.Schulte, E.C. ; Schramm, K. ; Schurmann, C. ; Lichtner, P. ; Herder, C. ; Roden, M. ; Gieger, C. ; Peters, A. ; Trenkwalder, C. ; Högl, B. ; Frauscher, B. ; Berger, K. ; Fietze, I. ; Gross, N. ; Stiasny-Kolster, K. ; Oertel, W. ; Bachmann, C.G. ; Paulus, W. ; ; Völzke, H. ; Schminke, U. ; Nauck, M. ; Illig, T. ; Meitinger, T. ; Müller-Myhsok, B. ; Prokisch, H. ; Winkelmann, J.
Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.Huang, H. ; Koelle, P. ; Fendler, M. ; Schröttle, A. ; Czihal, M. ; Hoffmann, U. ; Conrad, M. ; Kuhlencordt, P.J.
Induction of inducible Nitric Oxide Synthase (iNOS) expression by oxLDL inhibits macrophage derived foam cell migration.Peng, X. ; Mandal, P.K. ; Kaminskyy, V.O. ; Lindqvist, A. ; Conrad, M. ; Arner, E.S.J.
Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.Wirth, E.K. ; Bharathi, B.S. ; Hatfield, D.L. ; Conrad, M. ; Brielmeier, M. ; Schweizer, U.
Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons.Steib, K. ; Schäffner, I. ; Jagasia, R. ; Ebert, B. ; Lie, D.C.
Mitochondria modify exercise-induced development of stem cell-derived neurons in the adult brain.Hüttl, R.E. ; Huber, A.B.
Quantitative analysis of axonal outgrowth in mice.Zimprich, A. ; Garett, L. ; Deussing, J.M. ; Wotjak, C.T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wurst, W. ; Hölter, S.M.
A robust and reliable non-invasive test for stress responsivity in mice.Moreth, K. ; Fischer, R. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Katus, H.A. ; Bekeredjian, R. ; Hrabě de Angelis, M.
High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains.Dykes, I.M. ; van Bueren, K.L. ; Ashmore, R.J. ; Floß, T. ; Wurst, W. ; Szumska, D. ; Bhattacharya, S. ; Scambler, P.J.
HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.Piccoli, G. ; Onofri, F. ; Cirnaru, M.D. ; Kaiser, C.J. ; Jagtap, P.K. ; Kastenmüller, A. ; Pischedda, F. ; Marte, A. ; von Zweydorf, F. ; Vogt, A. ; Giesert, F. ; Pan, L. ; Antonucci, F. ; Kiel, C. ; Zhang, M. ; Weinkauf, S. ; Sattler, M. ; Sala, C. ; Matteoli, M. ; Ueffing, M. ; Gloeckner, C.J.
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.Pertek, A. ; Meier, F. ; Irmler, M. ; Beckers, J. ; Skylaki, S. ; Endele, M. ; Wurst, W. ; Prakash, N. ; Kühn, R.
Simple derivation of transgene-free iPS cells by a dual recombinase approach.Poschmann, G. ; Seyfarth, K. ; Besong Agbo, D. ; Klafki, H.-W. ; Rozman, J. ; Wurst, W. ; Wiltfang, J. ; Meyer, H.E. ; Klingenspor, M. ; Stühler, K.
High fat diet induced isoform changes of the Parkinson’s disease protein DJ-1.Westmeyer, G.G. ; Emer, Y. ; Lintelmann, J. ; Jasanoff, A.
MRI-based detection of alkaline phosphatase gene reporter activity using a porphyrin solubility switch.Spieler, D. ; Kaffe, M. ; Knauf, F. ; Bessa, J. ; Tena, J.J. ; Giesert, F. ; Schormair, B. ; Tilch, E. ; Lee, H. ; Horsch, M. ; Czamara, D. ; Karbalai, N. ; von Toerne, C. ; Waldenberger, M. ; Gieger, C. ; Lichtner, P. ; Claussnitzer, M. ; Naumann, R. ; Müller-Myhsok, B. ; Torres, M. ; Garrett, L. ; Rozman, J. ; Klingenspor, M. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Beckers, J. ; Hölter, S.M. ; Meitinger, T. ; Hauck, S.M. ; Laumen, H. ; Wurst, W. ; Casares, F. ; Gómez-Skarmeta, J.L. ; Winkelmann, J.
Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon.Pischedda, F. ; Szczurkowska, J. ; Cirnaru, M.D. ; Giesert, F. ; Vezzoli, E. ; Ueffing, M. ; Sala, C. ; Francolini, M. ; Hauck, S.M. ; Cancedda, L. ; Piccoli, G.
A cell surface biotinylation assay to reveal membrane-associated neuronal cues: Negr1 regulates dendritic arborization.Beckervordersandforth, R. ; Deshpande, A. ; Schäffner, I. ; Huttner, H.B. ; Lepier, A. ; Lie, D.C. ; Götz, M.
In vivo targeting of adult neural stem cells in the dentate gyrus by a split-cre approach.Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E. ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S. ; Reichert, A.S. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T. ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Polzer, H. ; Volkmer, E. ; Saller, M. ; Prall, W.C. ; Haasters, F. ; Drosse, I. ; Wilhelmi, A. ; Mutschler, W. ; Schieker, M.
Comparison of different strategies for in vivo seeding of prevascularized scaffolds.Tripathi, P.P. ; Giovannantonio, L.G. ; Sanguinetti, E. ; Acampora, D. ; Allegra, M. ; Caleo, M. ; Wurst, W. ; Simeone, A. ; Bozzi, Y.
Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behaviour and seizure susceptibility.di Giovannantonio, L.G. ; di Salvio, M. ; Omodei, D. ; Prakash, N. ; Wurst, W. ; Pierani, A. ; Acampora, D. ; Simeone, A.
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.Luxenhofer, G. ; Helmbrecht, M.S. ; Langhoff, J. ; Giusti, S.A. ; Refojo, D. ; Huber, A.B.
MicroRNA-9 promotes the switch from early-born to late-born motor neuron populations by regulating Onecut transcription factor expression.Wurst, W. ; Prakash, N.
Wnt1-regulated genetic networks in midbrain dopaminergic neuron development.Kirchner, M. ; Fegg, W. ; Römmelt, H. ; Leuchner, M. ; Ries, L. ; Zimmermann, R. ; Michalke, B. ; Wallasch, M. ; Maguhn, J. ; Faus-Kessler, T. ; Jakobi, G.
Nitrogen deposition along differently exposed slopes in the Bavarian Alps.Yan, X.
The role of Peroxidasin and Bmpr1b in eye development and diseases.