Publications
2024 Wissenschaftlicher Artikel in Science Advances Sci. Adv. 10:eadp6182 (2024)
Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition.
2024 Wissenschaftlicher Artikel in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 26, 4562-4570 (2024)
Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes.
2024 Wissenschaftlicher Artikel in Nature Neuroscience Nat. Neurosci. 27, 1758-1773 (2024)
A GnRH neuronal population in the olfactory bulb translates socially relevant odors into reproductive behavior in male mice.
2024 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.15796 (2024)
The role of incretin receptor agonists in the treatment of obesity.
2024 Wissenschaftlicher Artikel in eLife eLife 12:RP92075 (2024)
Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity.
2024 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-024-01021-8 (2024)
The interactions between energy homeostasis and neurovascular plasticity.
2024 Review in Cell Cell 187, 3829-3853 (2024)
Transforming obesity: The advancement of multi-receptor drugs.
2024 Wissenschaftlicher Artikel in Life Science Alliance Life Sci. All. 7:e202402828 (2024)
Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity.
2024 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 87:101992 (2024)
Experimental colonization with H. hepaticus, S. aureus and R. pneumotropicus does not influence the metabolic response to high-fat diet or incretin-analogues in wildtype SOPF mice.
2024 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 35, 566-568 (2024)
Antagonizing GIPR adds fire to the GLP-1R flame.
2024 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01078-9 (2024)
PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels.
2024 Review in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01079-8 (2024)
Obesity-induced inflammation: Connecting the periphery to the brain.
2024 Wissenschaftlicher Artikel in Science Science 384, 1111-1117 (2024)
Two-stage evolution of mammalian adipose tissue thermogenesis.
2024 Wissenschaftlicher Artikel in Endocrinology Endocrinology 165:bqae067 (2024)
Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ.
2024 Wissenschaftlicher Artikel in Facial Plastic Surgery Facial Plast. Surg., DOI: 10.1055/s-0044-1786185 (2024)
Characterization of fat used for the optimization of the soft tissue envelope of the nose in rhinoplasty.
2024 Letter to the Editor in Signal transduction and targeted therapy Signal Transduct. Target. Ther. 9:147 (2024)
Cellular precision modulation of JAK1: Tailoring therapies for allergic lung inflammation.
2024 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab., DOI: 10.1016/j.tem.2024.05.002 (2024)
Neuroendocrine gut-brain signaling in obesity.
2024 Review in Cell calcium Cell Calcium 121:102907 (2024)
Unravelling the complexity of the mitochondrial Ca2+ uniporter: Regulation, tissue specificity, and physiological implications.
2024 Wissenschaftlicher Artikel in Clinical Obesity Clin. Obes. 14:e12659 (2024)
IMPROVE 2022 International Meeting on pathway-related obesity: Vision of excellence.
2024 Review in Diabetes Therapy Diabetes Ther. 15, 1069-1084 (2024)
Dual and triple incretin-based co-agonists: Novel therapeutics for obesity and diabetes.
2024 Review in Peptides Peptides 176:171198 (2024)
Regulation of energy metabolism through central GIPR signaling.
2024 Wissenschaftlicher Artikel in Acta Neuropathologica Acta Neuropathol. 147:64 (2024)
Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion.
2024 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01025-8 (2024)
A spatiotemporal proteomic map of human adipogenesis.
2024 Letter to the Editor in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:104 (2024)
CVOT Summit Report 2023: New cardiovascular, kidney, and metabolic outcomes.
2024 Review in Frontiers in Molecular Biosciences Front. Mol. Biosci. 11:1347397 (2024)
Transfer of membrane(s) matter(s)-non-genetic inheritance of (metabolic) phenotypes?
2024 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 83:101915 (2024)
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.
2024 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 6, 448-457 (2024)
Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.
2024 Review in Frontiers in Nutrition Front. Nutr. 11:1322509 (2024)
Ketogenic diet and behavior: Insights from experimental studies.
2024 Review in Physiology Physiology 39, 142-156 (2024)
Pharmacological advances in incretin-based polyagonism - what we know and what we don'tt.
2024 Wissenschaftlicher Artikel in Nature Cell Biology Nat. Cell Biol. 26, 113–123 (2024)
EPAC1 enhances brown fat growth and beige adipogenesis.
2024 Wissenschaftlicher Artikel in Science Advances Sci. Adv. 10:eadi2689 (2024)
Transcriptional determinants of lipid mobilization in human adipocytes.
München, Technische Universität München, Fakultät für Medizin, Diss., 2023, 157 S.
The Role of Adipocyte-derived Extracellular Vesicles in Metabolic Diseases.
2023 Review in Frontiers in Molecular Biosciences Front. Mol. Biosci. 10:1336416 (2023)
Neither too much nor too little: Mitochondrial calcium concentration as a balance between physiological and pathological conditions.
2023 Masterclass in Neuroendocrinology Mast. Neuroend. 11, C1-C2 (2023)
Correction to: Control of Systemic Metabolism by Astrocytes in the Brain (Springer Nature, 10.1007/978-3-030-62383-8_6).
2023 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 79:101853 (2023)
Insulin regulates human pancreatic endocrine cell differentiation in vitro.
2023 Review in Science Translational Medicine Sci. Transl. Med. 15:eadh4453 (2023)
Seeking satiety: From signals to solutions.
2023 Wissenschaftlicher Artikel in Adipocyte Adipocyte:2283213 (2023)
Adipogenic characterization of immortalized CD55+ progenitor cells from human white adipose tissue.
2023 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 14:8175 (2023)
Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner.
2023 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 5, 2075–2085 (2023)
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.
2023 Wissenschaftlicher Artikel in Frontiers in Endocrinology Front. Endocrin. 14:1249863 (2023)
E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess.
2023 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, 335-338 (2023)
Regulation des Energiestoffwechsel durch GIP und GIPR:GLP-1R Ko-Agonisten.
2023 Editorial in Med (N Y) Med. 4, 849-851 (2023)
SURMOUNTing body weight barriers in type 2 diabetes.
2023 Wissenschaftlicher Artikel in BioSpektrum BioSpektrum 29, 137-139 (2023)
GLP-1-Mimetika – wegweisend zur Behandlung von Diabetes und Adipositas.
In: Encyclopedia of Human Nutrition: Volume 1-4, Fourth Edition. 2023. 161-167 ( ; 1-4)
Microbiota of the intestine: Biology and physiological functions.
2023 Editorial in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 11:1287533 (2023)
Editorial: Healthy adipose tissue expansion.
2023 Wissenschaftlicher Artikel in European Journal of Pharmacology Eur. J. Pharmacol. 960:176158 (2023)
Insights into the mechanism of action of the chlorophyll derivative 13-2-hydroxypheophytine a on reducing neutral lipid reserves in zebrafish larvae and mice adipocytes.
2023 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 42:113305 (2023)
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.
2023 Wissenschaftlicher Artikel in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 11:1240558 (2023)
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility.
2023 Wissenschaftlicher Artikel in Marine Drugs Mar. Drugs 21:498 (2023)
Metabolite profile characterization of cyanobacterial strains with bioactivity on lipid metabolism using in vivo and in vitro approaches.
2023 Editorial in Nature metabolism Nat. Metab. 5, 1454-1455 (2023)
Astrocytic GABA in LHA is an obesity ‘thermostat’.
2023 Wissenschaftlicher Artikel in Nature Cell Biology Nat. Cell Biol. 25, 975-988 (2023)
Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis.
2023 Wissenschaftlicher Artikel in BMC Biology BMC Biol. 21:150 (2023)
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice.
2023 Review in Biomolecules Biomolecules 13:41 (2023)
(Patho)physiology of glycosylphosphatidylinositol-anchored proteins II: Intercellular transfer of matter (Inheritance?) that matters.
2023 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 13:9908 (2023)
Placebo effects on nausea and motion sickness are resistant to experimentally-induced stress.
2023 Wissenschaftlicher Artikel in Nature Protocols Nat. Protoc. 18, 2181-2220 (2023)
Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice.
2023 Wissenschaftlicher Artikel in Stem Cell Reports Stem Cell Rep. 18, 1972-1986 (2023)
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.
2023 Review in Diabetologia Diabetologia 66, 1378-1394 (2023)
100 years of glucagon and 100 more.
2023 Wissenschaftlicher Artikel in Computers in Biology and Medicine Comput. Biol. Med. 163:107085 (2023)
Shared gene expression signatures between visceral adipose and skeletal muscle tissues are associated with cardiometabolic traits in children with obesity.
2023 Wissenschaftlicher Artikel in EMBO Reports EMBO Rep. 24:e57600 (2023)
The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.
2023 Wissenschaftlicher Artikel in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 11:1240039 (2023)
Inceptor facilitates acrosomal vesicle formation in spermatids and is required for male fertility.
2023 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 35, 1736-1751.e7 (2023)
Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration.
2023 Wissenschaftlicher Artikel in JAMA: Journal of the American Medical Association JAMA 330, 1151-1160 (2023)
SARS-CoV-2 infection and development of islet autoimmunity in early childhood.
2023 Review in Peptides Peptides 165:171003 (2023)
The molecular pharmacology of glucagon agonists in diabetes and obesity.
2023 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 72:101714 (2023)
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.
2023 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 14:1588 (2023)
Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis.
2023 Wissenschaftlicher Artikel in Nature Nature 615, 705-711 (2023)
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
2023 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:38 (2023)
Transfer of proteins from cultured human adipose to blood cells and induction of anabolic phenotype are controlled by serum, insulin and sulfonylurea drugs.
2023 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 35, 438-455.e7 (2023)
Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.
2023 Letter to the Editor in Cell Metabolism Cell Metab. 35, 377-379 (2023)
Protection from alcohol intoxication: Must be FGF21 to enter.
2023 Review in Nature metabolism Nat. Metab. 5, 933-944 (2023)
Gut hormone co-agonists for the treatment of obesity: From bench to bedside.
2023 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 5, 945-954 (2023)
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
2023 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 5, 861-879 (2023)
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes.
2023 Review in Biomolecules Biomolecules 13:41 (2023)
(Patho)Physiology of glycosylphosphatidylinositol-anchored proteins I: localization at plasma membranes and extracellular compartments.
2023 Wissenschaftlicher Artikel in Aging Cell Aging Cell 22:e13911 (2023)
Accelerated aging in mice with astrocytic redox imbalance as a consequence of SOD2 deletion.
2023 Review in Cell Metabolism Cell Metab. 35, 1519-1529 (2023)
GIPR/GLP-1R dual agonist therapies for diabetes and weight loss-chemistry, physiology, and clinical applications.
2023 Wissenschaftlicher Artikel in Pflügers Archiv Pflugers Arch. 475, 1149-1160 (2023)
Blood transcriptomics mirror regulatory mechanisms during hibernation-a comparative analysis of the Djungarian hamster with other mammalian species.
2023 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 35, 1373-1389.e8 (2023)
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting.
2023 Review in Diabetologia Diabetologia 66, 1780-1795 (2023)
Incretin hormones and type 2 diabetes.
2023 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 5, 1364-1381 (2023)
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.
2023 Wissenschaftlicher Artikel in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 25, 2171-2180 (2023)
Brain insulin responsiveness is linked to age and peripheral insulin sensitivity.
2023 Review in Innere Medizin Innere Med. 64, 629-635 (2023)
Adipositastherapie – werden Pharmakotherapien die Alternative zur metabolischen Chirurgie sein?
2023 Wissenschaftlicher Artikel in Cell Cell 186, 3706-3725.e29 (2023)
Distinct molecular profiles of skull bone marrow in health and neurological disorders.
2023 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:20 (2023)
Innova 2020: A follow-up study of the fecal microbiota of infants using a novel infant formula between 6 months and 12 months of age.
2023 Wissenschaftlicher Artikel in Frontiers in Genetics Front. Genet. 14:1128133 (2023)
Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa.
2023 Review in Diabetologia Diabetologia 66, 1796-1808 (2023)
Gut hormone-based pharmacology: Novel formulations and future possibilities for metabolic disease therapy.
2023 Wissenschaftlicher Artikel in Frontiers in Endocrinology Front. Endocrin. 14:1195677 (2023)
Atrial natriuretic peptide and leptin interactions in healthy men.
2023 Wissenschaftlicher Artikel in Cardiovascular Diabetology Cardiovasc. Diabetol. 22:217 (2023)
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.
2023 Wissenschaftlicher Artikel in World Journal of Pediatrics World J. Pediatr. 19, 864-872 (2023)
Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys.
2023 Wissenschaftlicher Artikel in Endocrinology Endocrinology 164:12 (2023)
Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice.
2023 Wissenschaftlicher Artikel in Diabetologia Diabetologia 66, 873-883 (2023)
Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response.
2023 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 69:101691 (2023)
Rest phase snacking increases energy resorption and weight gain in male mice.
2023 Wissenschaftlicher Artikel in Biological Psychiatry Biol. Psychiatry 94, 424-436 (2023)
The addiction-susceptibility TaqIA/Ankyrin repeat and kinase domain containing 1 kinase (ANKK1) controls reward and metabolism through dopamine receptor type 2 (D2R)-expressing neurons.
2023 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:25 (2023)
Effects of a novel infant formula on the fecal microbiota in the first six months of life: The INNOVA 2020 Study.
2023 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 14:709 (2023)
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.
2023 Review in Journal of Clinical Investigation J. Clin. Invest. 133:4 (2023)
Dual gut hormone receptor agonists for diabetes and obesity.
2023 Wissenschaftlicher Artikel in Nutrients Nutrients 15:147 (2023)
Effects of a novel infant formula on weight gain, body composition, safety and tolerability to infants: The INNOVA 2020 Study.
2023Vortrag: American Diabetes Association 83rd Scientific Sessions, Jun 23, 2023 - Jun 2, San Diego Convention Center. San Diego, CA, United States. (2023)
ScRNAseq based analysis of the stromal immune cell composition in murine pre-weaning and adult white adipose tissues .
2023 Wissenschaftlicher Artikel in JCI insight JCI insight 8:e163397 (2023)
TRPM7 kinase is required for insulin production and compensatory islet responses during obesity.
2023 Review in Advances in Experimental Medicine and Biology Adv. Exp. Med. Biol. 1396, 215-232 (2023)
Genome editing and protein energy malnutrition.
2022 Wissenschaftlicher Artikel in Bioinformatics Advances Bioinfo. Adv. 2:vbac042 (2022)
Correlation-guided Network Integration (CoNI), an R package for integrating numerical omics data that allows multiform graph representations to study molecular interaction networks.
2022 Wissenschaftlicher Artikel in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2204527119 (2022)
Insulin regulates neurovascular coupling through astrocytes.
2022 Wissenschaftlicher Artikel in Frontiers in Nutrition Front. Nutr. 9:992682 (2022)
Intake of slow-digesting carbohydrates is related to changes in the microbiome and its functional pathways in growing rats with obesity induced by diet.
2022 Wissenschaftlicher Artikel in Leukemia Leukemia 37, 288-297 (2022)
A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients.
2022 Wissenschaftlicher Artikel in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 10:965382 (2022)
Age-dependent increase of cytoskeletal components in sensory axons in human skin.
2022 Letter to the Editor in Lancet, The Lancet 400, 1826-1828 (2022)
Gut-hormone triple agonists: Clinical safety and metabolic benefits.
2022 Wissenschaftlicher Artikel in Allergy Allergy 78, 1218-1233 (2022)
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice.
2022 Wissenschaftlicher Artikel in Journal of Pharmaceutical and Biomedical Analysis : JPBA J. Pharm. Biomed. Anal. 221:115038 (2022)
Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain.
2022 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 64:101556 (2022)
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.
2022 Wissenschaftlicher Artikel in Nature Nature 609, 361–368 (2022)
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
2022 Wissenschaftlicher Artikel in Glia Glia 70, 2062-2078 (2022)
Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner.
2022 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 66:101616 (2022)
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
2022 Wissenschaftlicher Artikel in Brain and behavior Brain Behav. 12:e2685 (2022)
Central correlates of placebo effects in nausea differ between men and women.
2022 Wissenschaftlicher Artikel in EBioMedicine EBioMedicine 82:104118 (2022)
A classification and regression tree analysis identifies subgroups of childhood type 1 diabetes.
2022 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 34, 1824-1842.e9 (2022)
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
2022 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 4, 1071-1083 (2022)
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
2022 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 34, 1532-1547.e6 (2022)
Hypothalamic astrocytes control systemic glucose metabolism and energy balance.
2022 Wissenschaftlicher Artikel in Genome Biology Genome Biol. 23:207 (2022)
H3K18 lactylation marks tissue-specific active enhancers.
2022 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 4, 883-900 (2022)
Food-seeking behavior is triggered by skin ultraviolet exposure in males.
2022 Wissenschaftlicher Artikel in JCI insight JCI insight 7:e161498 (2022)
Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese.
2022 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 12:10325 (2022)
Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens.
2022 Wissenschaftlicher Artikel in The journal of experimental biology J. Exp. Biol. 225:jeb243860 (2022)
Obligatory homeothermy of mesic adapted African striped mice, Rhabdomys pumilio, is governed by seasonal basal metabolism and year-round "thermogenic readiness" of brown adipose tissue.
2022 Wissenschaftlicher Artikel in Methods in Molecular Biology Methods Mol. Biol. 2456, 123-140 (2022)
Phosphoproteomics and organelle proteomics in pancreatic islets.
Methods in Molecular Biology In: Circadian Regulation. 2022. 311-327 (Methods Mol. Biol. ; 2482)
Untargeted and targeted circadian metabolomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and flow injection-electrospray ionization-tandem mass spectrometry (FIA-ESI-MS/MS).
2022 Wissenschaftlicher Artikel in Computers in Biology and Medicine Comput. Biol. Med. 149:106049 (2022)
Computational exploration of the dual role of the phytochemical fortunellin: Antiviral activities against SARS-CoV-2 and immunomodulatory abilities against the host.
2022 Wissenschaftlicher Artikel in Life Sciences Life Sci. 303:120601 (2022)
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain.
2022 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 61:101508 (2022)
PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes.
2022 Wissenschaftlicher Artikel in Nutrients Nutrients 14:1922 (2022)
L-serine supplementation blunts fasting-induced weight regain by increasing brown fat thermogenesis.
2022 Wissenschaftlicher Artikel in Brain: A Journal of Neurology Brain 145, 4264-4274 (2022)
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency.
2022 Wissenschaftlicher Artikel in BMC Microbiology BMC Microbiol. 22:91 (2022)
Pharmacologically induced weight loss is associated with distinct gut microbiome changes in obese rats.
2022 Review in Frontiers in Endocrinology Front. Endocrin. 13:859044 (2022)
Immune cell regulation of white adipose progenitor cell fate.
2022 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:7418 (2022)
Biological role of the intercellular transfer of glycosylphosphatidylinositol-anchored proteins: Stimulation of lipid and glycogen synthesis.
2022 Review in Frontiers in Endocrinology Front. Endocrin. 13:838410 (2022)
Recent advances in incretin-based pharmacotherapies for the treatment of obesity and diabetes.
2022 Review in Biomedicines Biomedicines 10:126 (2022)
Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism.
2022 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 33, 493-506 (2022)
Regulatory networks determining substrate utilization in brown adipocytes.
2022 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 39:110835 (2022)
Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression.
2022 Wissenschaftlicher Artikel in Journal of Immunological Methods J. Immunol. Methods 502:113227 (2022)
Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment.
2022 Wissenschaftlicher Artikel in BMJ Open BMJ Open 12:e058268 (2022)
The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: Rationale, methodology and design.
2022 Sonstiges: Nachrichtenmeldung in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-022-00563-3 (2022)
Astroglial clean-up of satiety synapses.
2022 Wissenschaftlicher Artikel in EMBO Molecular Medicine EMBO Mol. Med.:e14797 (2022)
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
2022 Wissenschaftlicher Artikel in Neuron Neuron 110, 1516-1531.e9 (2022)
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy.
2022 Sonstiges: Nachrichtenmeldung in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 263–264 (2022)
An updated view on human neonatal thermogenesis.
2022 Wissenschaftlicher Artikel in Allergy Allergy 77, 2482-2497 (2022)
Differential effects of lung inflammation on insulin resistance in humans and mice.
2022 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 34, 329-345.e8 (2022)
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
2022 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 38:110270 (2022)
Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion.
2022 Wissenschaftlicher Artikel in Developmental Cell Dev. Cell 57, 387-397.e4 (2022)
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.
2022 Review in Nature Reviews - Drug Discovery Nat. Rev. Drug Discov. 21, 201-223 (2022)
Anti-obesity drug discovery: Advances and challenges.
2022 Editorial in Gut (eGut) Gut 71, 2147-2148 (2022)
Is epiploic fat the dermal fat of the intestine?
Masterclass in Neuroendocrinology In: Neuroanatomy of Neuroendocrine Systems. 2021. 317-346 (Mast. Neuroend. ; 12)
The Neuroanatomical Organization of Hypothalamic Feeding Circuits.
Masterclass in Neuroendocrinology In: Glial-Neuronal Signaling in Neuroendocrine Systems. 2021. 127-154 (Mast. Neuroend. ; 11)
Control of Systemic Metabolism by Astrocytes in the Brain.
2021 Wissenschaftlicher Artikel in Life Life 11:1393 (2021)
Physiological doses of hydroxytyrosol modulate gene expression in skeletal muscle of exercised rats.
2021 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:12526 (2021)
Synaptotagmin-13 is a neuroendocrine marker in brain, intestine and pancreas.
2021 Review in Journal of Cellular Biochemistry J. Cell. Biochem., DOI: 10.1002/jcb.30179 (2021)
Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise.
2021 Wissenschaftlicher Artikel in Biomedicines Biomedicines 9:1452 (2021)
Chip-based sensing of the intercellular transfer of cell surface proteins: Regulation by the metabolic state.
2021 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 54:101348 (2021)
Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels.
2021 Review in Nutrients Nutrients 13:3999 (2021)
Impact of exercise on gut microbiota in obesity.
2021 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 3, 1415-1431 (2021)
Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.
2021 Wissenschaftlicher Artikel in Life Science Alliance Life Sci. All. 4:e202101013 (2021)
Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress.
2021 Nature metabolism Nat. Metab. 3:1433 (2021)
Publisher Correction: Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.
2021 Review in Metabolites Metabolites 11:732 (2021)
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2020 Nature metabolism Nat. Metab. 2, 380 (2020)
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2020 Meeting abstract in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 393, 18-19 (2020)
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2020 Editorial in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:383 (2020)
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2020 Review in Journal of physiology and biochemistry J. Physiol. Biochem. 76, 193-211 (2020)
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2020 Review in Peptides Peptides 125:170225 (2020)
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2020 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 31, 13-24 (2020)
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2019 Molecular Metabolism Mol. Metab. 30:264 (2019)
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2019 Molecular Metabolism Mol. Metab. 30, 265-265 (2019)
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2019 Meeting abstract in Diabetologia Diabetologia 62, S136-S136 (2019)
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2019 Letter to the Editor in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 381:e17 (2019)
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2019 Meeting abstract in European Neuropsychopharmacology : ENP Eur. Neuropsychopharmacol. 29, 1138-1138 (2019)
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2019 Review in Journal of Clinical Investigation J. Clin. Invest. 130, 4058-4071 (2019)
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2019 Wissenschaftlicher Artikel in FASEB Journal FASEB J. 33, 12087-12098 (2019)
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2019 Review in Contact Contact 2, DOI: 10.1177/2515256419859186 (2019)
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2019 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 133, S794-S795 (2019)
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2019 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 133, S780-S780 (2019)
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2019 Wissenschaftlicher Artikel in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 317, https://doi.org/ 10.6084/m9.figshare.7994312.v1, E212-E233 (2019)
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TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.
2019 Wissenschaftlicher Artikel in Molecular Systems Biology Mol. Syst. Biol. 15:e8793 (2019)
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease.
Methods in Molecular Biology In: Calcium Signalling. 2019. 197-222 (Methods Mol. Biol. ; 1925)
Assessing calcium-stimulated mitochondrial bioenergetics using the seahorse XF96 analyzer.
2019 Wissenschaftlicher Artikel in Nature metabolism Nat. Metab. 1, 222-235 (2019)
Functional identity of hypothalamic melanocortin neurons depends on Tbx3.
2019 Wissenschaftlicher Artikel in Nature Nature 567, 113-117 (2019)
The centrosome protein AKNA regulates neurogenesis via microtubule organization.
2019 Wissenschaftlicher Artikel in Nutrients Nutrients 11:337 (2019)
Autism Spectrum Disorder (ASD) with and without mental regression is associated with changes in the fecal microbiota.
2019 Wissenschaftlicher Artikel in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 316, E615-E621 (2019)
Effect of bariatric surgery on plasma GDF15 in humans.
2019 Wissenschaftlicher Artikel in EMBO Reports EMBO Rep. 20:e46451 (2019)
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
2019 Wissenschaftlicher Artikel in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 316, E866-E879 (2019)
Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans.
2019Poster: Keystone Symposia, 11-14 February 2019, Banff, Canada. (2019)
Defining murine brown adipose tissue heterogeneity
2019 Meeting abstract in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 392, S35-S35 (2019)
Tri-agonist-induced PLC activation is associated with robust insulin secretion from murine islets.
2019 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 20, 51-62 (2019)
Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism.
2019 Review in Nature Neuroscience Nat. Neurosci. 22, 7-14 (2019)
Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism.
2019 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 20, 28-37 (2019)
Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin.
2019 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 15, 90-104 (2019)
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases.
2019 Wissenschaftlicher Artikel in Gastroenterology Gastroenterology 156, 692-707.e7 (2019)
Alternative splice forms of CYLD mediate ubiquitination of SMAD7 to prevent TGFB signaling and promote colitis.
2019 Wissenschaftlicher Artikel in Gastroenterology Gastroenterology 156, 203-217.e20 (2019)
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.
2019 Wissenschaftlicher Artikel in International Journal of Obesity Int. J. Obes. 43, 1305-1318 (2019)
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.
2018 Diabetes Diabetes 67, 343-344 (2018)
Erratum. Adipocyte glucocorticoid Receptor deficiency attenuates aging- and HFD-induced obesity and impairs the feeding-fasting transition. Diabetes 2017;66:272-286.
2018 Wissenschaftlicher Artikel in Frontiers in psychiatry Front. Psychiatr. 9:706 (2018)
Effects of placebo interventions on subjective and objective markers of appetite-a randomized controlled trial.
2018 Wissenschaftlicher Artikel in EMBO Journal, The EMBO J. 37:e99291 (2018)
Developmental and functional heterogeneity of white adipocytes within a single fat depot.
2018 Wissenschaftlicher Artikel in Journal of Medicinal Chemistry J. Med. Chem. 61, 11144-11157 (2018)
Celastrol promotes weight loss in diet-induced obesity by inhibiting the protein tyrosine phosphatases PTP1B and TCPTP in the hypothalamus.
2018 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 25, 3241-3251.e5 (2018)
The aryl hydrocarbon receptor pathway defines the time frame for restorative neurogenesis.
2018 Nature Communications Nat. Commun. 9:4975 (2018)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018).
2018 Wissenschaftlicher Artikel in Frontiers in Endocrinology Front. Endocrin. 9:673 (2018)
Family history of diabetes is associated with delayed fetal postprandial brain activity.
2018 Review in Journal of Internal Medicine J. Intern. Med. 284, 581-602 (2018)
Peptide-based multi-agonists: A new paradigm in metabolic pharmacology.
2018 Meeting abstract in Wiener medizinische Wochenschrift Wien. Med. Wochenschr. 130, 348-348 (2018)
Posture of adipose Mice under hypoxia reduces Hyperglycemia without Improving Insulin Sensitivity.
2018 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 25, 1425-1435 (2018)
MICU1 confers protection from MCU-dependent manganese toxicity.
2018 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 9:4304 (2018)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
2018 Wissenschaftlicher Artikel in Developmental Cell Dev. Cell 47, 205-221.e7 (2018)
Organellar proteomics and phospho-proteomics reveal subcellular teorganization in diet-induced hepatic steatosis.
2018 Review in Endocrine Reviews Endocr. Rev. 39, 719-738 (2018)
Targeting the incretin/glucagon system with triagonists to treat diabetes.
2018 Sonstiges: Meinungsartikel in Lancet, The Lancet 392, 2142-2144 (2018)
Twice the benefits with twincretins?
Nova Science Publishers, 2018.
Glycosylphosphatidylinositol-anchored proteins and their release from cells: From phenomenon to meaning.
2018 Wissenschaftlicher Artikel in Aging Cell Aging Cell 17:e12810 (2018)
Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism.
2018 Wissenschaftlicher Artikel in Cellular and Molecular Gastroenterology and Hepatology Cell. Mol. Gast. Hept. 6, 429-449 (2018)
Glycemic variability promotes both local invasion and metastatic colonization by pancreatic ductal adenocarcinoma.
2018 Wissenschaftlicher Artikel in Human Molecular Genetics Hum. Mol. Genet. 27, 3099-3112 (2018)
A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.
2018 Review in Pharmacological Research Pharmacol. Res. 137, 11-24 (2018)
Uncoupling proteins as a therapeutic target to protect the diabetic heart.
2018 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 17, 112-121 (2018)
Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements.
2018 Wissenschaftlicher Artikel in Diabetes Diabetes 67, 2456-2465 (2018)
Celastrol-induced weight loss is driven by hypophagia and independent from UCP1.
2018 Wissenschaftlicher Artikel in Journal of Immunological Methods J. Immunol. Methods 463, 54-60 (2018)
CD4+ T cell activation, function, and metabolism are inhibited by low concentrations of DMSO.
2018 Review in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 656, 1-18 (2018)
The release of glycosylphosphatidylinositol-anchored proteins from the cell surface.
2018 Review in Pharmacological reviews Pharmacol. Rev. 70, 712-746 (2018)
Anti-obesity therapy: From rainbow pills to polyagonists.
2018 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab., DOI: 10.1016/j.molmet.2018.07.002 (2018)
Chronic d-serine supplementation impairs insulin secretion.
2018 Review in Diabetologie, Die Diabetologie 14, 486-492 (2018)
Mit Big Data zur personalisierten Diabetesprävention.
2018 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 9:3432 (2018)
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
2018 Wissenschaftlicher Artikel in Cell Cell 174, 1571-1585.e11 (2018)
Atlas of circadian metabolism reveals system-wide coordination and communication between clocks.
2018 Wissenschaftlicher Artikel in PLoS Biology PLoS Biol. 16:e2005886 (2018)
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
2018 Wissenschaftlicher Artikel in Science Science 361:eaar7191 (2018)
Shifting the limits in wheat research and breeding using a fully annotated reference genome.
2018 Wissenschaftlicher Artikel in Cellular Signalling Cell. Signal. 51, 13-22 (2018)
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.
2018 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 8:11335 (2018)
Streptozotocin-induced beta-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
2018 Editorial in Frontiers in Physiology Front. Physiol. 9:891 (2018)
Editorial: The evolution of endothermy-from patterns to mechanisms.
2018 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 8:10723 (2018)
Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.
2018 Review in Trends in Pharmacological Sciences Trends Pharmacol. Sci. 39, 685-694 (2018)
Ghrelin and LEAP-2: Rivals in energy metabolism.
2018 Wissenschaftlicher Artikel in Integrative and comparative biology Integ. & comp. biol. 58, 495-505 (2018)
Comparing electron leak in vertebrate muscle mitochondria.
2018 Wissenschaftlicher Artikel in Journal of Lipid Research J. Lipid Res. 59, 1649-1659 (2018)
Circulating HDL levels control hypothalamic astrogliosis via apoA-I.
2018 Wissenschaftlicher Artikel in Clinical Immunology Clin. Immunol. 194, 87-91 (2018)
Novel minor HLA DR associated antigens in type 1 diabetes.
2018 Wissenschaftlicher Artikel in Obesity Facts Obes. Facts 11, 93-108 (2018)
The effect of SH2B1 variants on expression of leptin- and insulin-induced pathways in murine hypothalamus.
2018 Wissenschaftlicher Artikel in Obesity Obesity 26, 895-902 (2018)
Neural food reward processing in successful and unsuccessful weight maintenance.
2018 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab., DOI: 10.1016/j.molmet.2018.06.015 (2018)
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.
2018 Wissenschaftlicher Artikel in Diabetes Diabetes 67, 1773-1782 (2018)
Glucagon receptor signaling regulates energy metabolism via hepatic farnesoid X receptor and fibroblast growth factor 21.
2018 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 23, 3112-3125 (2018)
Prediction of adipose browning capacity by systematic integration of transcriptional profiles.
2018 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 28, 159-+ (2018)
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
2018 Review in Journal of Endocrinology J. Endocrinol. 238, R109-R119 (2018)
Are peptide conjugates the golden therapy against obesity?
2018 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 13, 77-82 (2018)
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice.
2018 Wissenschaftlicher Artikel in Circulation Circulation 138, 2007-2020 (2018)
Dicer in macrophages prevents atherosclerosis by promoting mitochondrial oxidative metabolism.
2018 Review in Journal of Physiology - Paris J. Physiol. 596, 2717-2733 (2018)
Pharmacological modulation of mitochondrial calcium homeostasis.
2018 Wissenschaftlicher Artikel in Journal of Visualized Experiments J. Vis. Exp. 2018:e56752 (2018)
Real-time analysis of Ttanscription factor binding, transcription, translation, and turnover to display global events during cellular activation.
2018 Review in The journal of experimental biology J. Exp. Biol. 221, 1:jeb162958 (2018)
Heterogeneity of adipose tissue in development and metabolic function.
2018 Wissenschaftlicher Artikel in Cancer Cell Cancer Cell 33, 770-784.e6 (2018)
Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor.
2018 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 22, 3072-3086 (2018)
Diet, genetics, and the gut microbiome drive dynamic changes in plasma metabolites.
2018 Review in The journal of experimental biology J. Exp. Biol. 121, 1:jeb169425 (2018)
Insights into brown adipose tissue evolution and function from non-model organisms.
2018 Wissenschaftlicher Artikel in Peptides Peptides 100, 18-23 (2018)
Controlled intramolecular antagonism as a regulator of insulin receptor maximal activity.
2018 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 9, 187-191 (2018)
Exercise increases circulating GDF15 in humans.
2018 Wissenschaftlicher Artikel in Hearing Research Hear. Res. 363, 70-77 (2018)
Fetal auditory evoked responses to onset of amplitude modulated sounds. A fetal magnetoencephalography (fMEG) study.
2018 Review in Current Opinion in Clinical Nutrition & Metabolic Care Curr. Opin. Clin. Nutr. Metab. Care 21, 164-167 (2018)
Skeletal muscle mass is controlled by the MRF4-MEF2 axis.
2018 Wissenschaftlicher Artikel in PLoS Biology PLoS Biol. 16:e2003992 (2018)
Mitochondria are physiologically maintained at close to 50 °C.
2018 Review in Journal of Peptide Science J. Pept. Sci. 24:e3056 (2018)
Max Bergmann award lecture: Macromolecular medicinal chemistry as applied to metabolic diseases.
2018 Wissenschaftlicher Artikel in Peptides Peptides 100, 236-242 (2018)
Ghrelin regulation of glucose metabolism.
2018 Wissenschaftlicher Artikel in Journal of Neuroinflammation J. Neuroinflamm. 15:35 (2018)
Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice.
2018 Review in Peptides Peptides 100, 190-201 (2018)
Gut hormone polyagonists for the treatment of type 2 diabetes.
2018 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 8:2736 (2018)
Oxytocin curbs calorie intake via food-specific increases in the activity of brain areas that process reward and establish cognitive control.
2018 Review in Experimental Physiology Exp. Physiol. 103, 157-169 (2018)
Crosslink between calcium and sodium signalling.
2018 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 9:288 (2018)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
2018 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 9, 4-14 (2018)
Respiromics - An integrative analysis linking mitochondrial bioenergetics to molecular signatures.
2018 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 8:1388 (2018)
Attentional and physiological processing of food images in functional dyspepsia patients: A pilot study.
2018 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 14, 140-162 (2018)
Animal models of obesity and diabetes mellitus.
2018 Review in Seminars in Immunopathology Semin. Immunopathol. 40, 215-224 (2018)
Hemostasis, endothelial stress, inflammation, and the metabolic syndrome.
2018 Wissenschaftlicher Artikel in Cancer Letters Cancer Lett. 415, 129-150 (2018)
Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells.
2018 Wissenschaftlicher Artikel in Cell Cell 172, 409–422.e21 (2018)
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.
2018 Wissenschaftlicher Artikel in Journal of Autoimmunity J. Autoimmun. 89, 63-74 (2018)
Allele-specific methylation of type 1 diabetes susceptibility genes.
2018 Review in Trends in Biochemical Sciences : TIBS Trends Biochem. Sci. 43, 1-4 (2018)
Immune responses - Transcriptional and post-transcriptional networks pass the baton.
2018 Wissenschaftlicher Artikel in Biomedical Chromatography Biomed. Chromatogr. 32:e4151 (2018)
Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine (C57Bl/6J) tissues.
2018 Wissenschaftlicher Artikel in Endocrinology Endocrinology 159, 400-413 (2018)
Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: A potential role for fibroblast growth factor-21.
2018 Wissenschaftlicher Artikel in Mitochondrion Mitochondrion, DOI: 10.1016/j.mito.2017.08.015 (2018)
Mitochondrial adaptation in steatotic mice.
2018 Wissenschaftlicher Artikel in International Journal of Obesity Int. J. Obes. 42, 507-517 (2018)
A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue.
2017 Wissenschaftlicher Artikel in Bio-Protocol Bio Protoc. 7:e2521 (2017)
An ex vivo perifusion method for quantitative determination of neuropeptide release from mouse hypothalamic explants.
2017 Wissenschaftlicher Artikel in European Journal of Endocrinology Eur. J. Endocrinol. 176, 123-132 (2017)
Acute administration of acyl, but not desacyl ghrelin, decreases blood pressure in healthy humans.
München, Technische Universität, Fakultät für Medizin, Diss., 2017, 88 S.
The role of mitochondrial fission protein Drp1 in pancreatic islets and beta cells.
Peter Lang GmbH, 2017. 359 Seiten
Gesundheit – Vom (bio)technologischen, (eigen)verantwortlichen, fairen und realistischen Umgang.
München, Technische Universität, Fakultät für Medizin, Diss., 2017, 86 S.
Energy deprivation induces a specific secretome in skeletal muscle.
2017 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 47, 186-186 (2017)
Linking TNF receptor signaling in virus-infected hepatocytes to cell death for immune control of liver infection.
2017 Wissenschaftlicher Artikel in Data in Brief Data Brief 15, 163-169 (2017)
Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks.
2017 Wissenschaftlicher Artikel in Nature Immunology Nat. Immunol. 19, 130–140 (2017)
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.
2017 Meeting abstract in Free Radical Biology and Medicine Free Radical Biol. Med. 112, 24-24 (2017)
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.
2017 Meeting abstract in Medicine & Science in Sports & Exercise Med. Sci. Sports Exerc. 49, 702-702 (2017)
Role of neuronal fractalkine in reducing diet-induced hypothalamic inflammation.
2017 Wissenschaftlicher Artikel in Bioorganic and Medicinal Chemistry Bioorg. Med. Chem. 26, 2873-2881 (2017)
Optimization of peptide-based polyagonists for treatment of diabetes and obesity.
2017 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 8:1725 (2017)
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.
2017 Wissenschaftlicher Artikel in Frontiers in Physiology Front. Physiol. 8:909 (2017)
Mitochondrial proton leak compensates for reduced oxidative power during frequent hypothermic events in a protoendothermic mammal, Echinops telfairi.
2017 Wissenschaftlicher Artikel in Hormone and Metabolic Research Horm. Metab. Res. 49, 892-898 (2017)
Thymus growth and fetal immune responses in diabetic pregnancies.
2017 Wissenschaftlicher Artikel in Neuron Neuron 96, 713-715 (2017)
A synaptic basis for GLP-1 action in the brain.
2017 Wissenschaftlicher Artikel in Journal of Clinical Investigation J. Clin. Invest. 127, 4148-4162 (2017)
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.
2017 Wissenschaftlicher Artikel in PLoS ONE PLoS ONE 12:e0187192 (2017)
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb.
2017 Wissenschaftlicher Artikel in Diabetes Diabetes 66, 2822-2829 (2017)
Tbx15 defines a glycolytic subpopulation and white adipocyte heterogeneity.
2017 Wissenschaftlicher Artikel in Diabetologie, Die Diabetologie 13, 505–513 (2017)
Inkretinbasierte Medikamente zur Diabetes- und Adipositastherapie. Entwicklungsperspektiven.
2017 Wissenschaftlicher Artikel in Science Advances Sci. Adv. 3:e1602878 (2017)
Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades.
2017 Wissenschaftlicher Artikel in American Journal of Psychiatry, The Am. J. Psychiatry 174, 850-858 (2017)
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa.
2017 Review in Cell Metabolism Cell Metab. 26, 585-587 (2017)
Dietary carbohydrates impair healthspan and promote mortality.
2017 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 20, 3034-3042 (2017)
Lipoprotein lipase maintains microglial innate immunity in obesity.
2017 Wissenschaftlicher Artikel in Obesity Obesity 25, 1647-1649 (2017)
Emerging poly-agonists for obesity and type 2 diabetes.
2017 Wissenschaftlicher Artikel in Frontiers in Physiology Front. Physiol. 8:704 (2017)
Comparison of mitochondrial reactive oxygen species production of ectothermic and endothermic fish muscle.
2017 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 26, 620-632.e6 (2017)
Molecular integration of incretin and glucocorticoid action reverses immunometabolic dysfunction and obesity.
2017 Wissenschaftlicher Artikel in PLoS ONE PLoS ONE 12:e0183488 (2017)
Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice.
2017 Wissenschaftlicher Artikel in Oncogene Oncogene 36, 4987-4996 (2017)
Insulin resistance in vascular endothelial cells promotes intestinal tumour formation.
2017 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 26, 475-492.e7 (2017)
A Stat6/Pten axis links regulatory T cells with adipose tissue function.
2017 Editorial in Cell Stem Cell Cell Stem Cell 21, 153-155 (2017)
Engineering skin with skinny genes.
2017 Editorial in Cell Metabolism Cell Metab. 26, 289-291 (2017)
Once blind, now we see GLP-1 molecular action.
2017 Wissenschaftlicher Artikel in Molecular Cell Mol. Cell 67, 711-723.e7 (2017)
Systematic identification of MCU modulators by orthogonal Iiterspecies chemical screening.
Wissenschaftlicher Artikel in Endocrine Development In: (10th ESPE Advanced Seminar in Developmental Endocrinology, 10 June 2016, Ulm). 2017. 165-182 (Endocr. Dev. ; 32)
Treatment of diabetes and obesity by rationally designed peptide agonists functioning at multiple metabolic receptors.
2017 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 7:8888 (2017)
Extracellular calcium modulates brown adipocyte differentiation and identity.
2017 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 26, 343-352.e2 (2017)
The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes.
2017 Review in Frontiers in Endocrinology Front. Endocrin. 8:197 (2017)
Hypothalamic inflammation and energy balance disruptions: Spotlight on chemokines.
2017 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 26, 437-446.e5 (2017)
Long-term cold adaptation does not require FGF21 or UCP1.
2017 Review in Diabetologia Diabetologia 60, 1851–1861 (2017)
GLP-1/glucagon receptor co-agonism for treatment of obesity.
2017 Sonstiges: Meinungsartikel in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 7744-7746 (2017)
Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue.
2017 Wissenschaftlicher Artikel in Diabetes Aktuell Diabetes akt. 15, 109-111 (2017)
Das Gehirn als Schaltzentrale des Stoffwechsels.
2017 Wissenschaftlicher Artikel in Diabetes Diabetes 66, 2555-2563 (2017)
Disruption of lipid uptake in astroglia exacerbates diet induced obesity.
2017 Wissenschaftlicher Artikel in Journal of Nuclear Medicine J. Nucl. Med. 58, 1100-1103 (2017)
Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein 1 deficient mice.
2017 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 6, 1226-1239 (2017)
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors.
2017 Wissenschaftlicher Artikel in Nature Neuroscience Nat. Neurosci. 20, 1096-1103 (2017)
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
2017 Wissenschaftlicher Artikel in Nature medicine Nat. Med. 23, 829-838 (2017)
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Diabetes In:. Alexandria: Amer Diabetes Assoc, 2017. 1766-1769 (Diabetes ; 66)
Single-molecule combinatorial therapeutics for treating obesity and diabetes.
2017 Wissenschaftlicher Artikel in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, E5167-E5176 (2017)
Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins.
2017 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 6, 897-908 (2017)
Dietary sugars, not lipids, drive hypothalamic inflammation.
2017 Meeting abstract in Glia Glia 65, E511-E511 (2017)
Hypercaloric environment triggers chronic remodeling of the hypothalamic vasculature via astroglial HIF1 alpha and VEGF signaling.
2017 Meeting abstract in Glia Glia 65, E219-E219 (2017)
Astrocytic leptin and insulin signals interact to maintain systemic metabolic homeostasis.
2017 Meeting abstract in Glia Glia 65, E218-E218 (2017)
Hypothalamic astrocyte activity state determines systemic glucose metabolism in mice.
2017 Meeting abstract in Glia Glia 65, E217-E218 (2017)
Astrocytic UCP2 is required for hypothalamic response to metabolic challenges.
2017 Meeting abstract in Glia Poster: (2017)
Mitochondrial function in Pink1 deficient astrocytes.
2017 Wissenschaftlicher Artikel in International Immunology Int. Immunol. 29, 173-181 (2017)
Splicing in immune cells - mechanistic insights and emerging topics.
2017 Wissenschaftlicher Artikel in Journal of Physiology - Paris J. Physiol. 595, 4845-4855 (2017)
Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice.
2017 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 8:15069 (2017)
Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.
2017 Wissenschaftlicher Artikel in Cell Reports Cell Rep. 19, 643-654 (2017)
Rapid genome-wide recruitment of RNA polymerase II drives transcription, splicing, and translation events during T cell responses.
2017 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 18:798 (2017)
Therapeutic potential of targeting the ghrelin pathway.
2017 Wissenschaftlicher Artikel in Inorganic Chemistry Inorg. Chem. 56, 3123-3126 (2017)
Synthetic methods for the preparation of a functional analogue of Ru360, a potent inhibitor of mitochondrial calcium uptake.
2017 Wissenschaftlicher Artikel in Diabetes Diabetes 66, 886-896 (2017)
Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor.
2017 Wissenschaftlicher Artikel in Neuroscience Neuroscience 357, 241-254 (2017)
Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.
2017 Wissenschaftlicher Artikel in Archives of Toxicology Arch. Toxicol. 91, 3427–3438 (2017)
Time-matched analysis of DNA adduct formationand early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.
2017 Wissenschaftlicher Artikel in Diabetes Diabetes 66, 1511-1520 (2017)
Endothelial HIF-1α enables hypothalamic glucose uptake to drive POMC neurons.
2017 Wissenschaftlicher Artikel in Cell Metabolism Cell Metab. 25, 1334-1347.e4 (2017)
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.
2017 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 7:44661 (2017)
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
2017 Wissenschaftlicher Artikel in Biologie aujourd'hui Biol. Aujourdhui 210, 211-225 (2017)
[Hypothalamic inflammation and energy balance deregulations: Focus on chemokines.].
2017 Wissenschaftlicher Artikel in Diabetologia Diabetologia 60, 1314-1324 (2017)
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.
2017 Wissenschaftlicher Artikel in Physiological Reviews Physiol. Rev. 97, 721-766 (2017)
The new biology and pharmacology of glucagon.
2017 Wissenschaftlicher Artikel in Cell Death and Differentiation Cell Death Differ. 24, 761-773 (2017)
SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.
2017 Wissenschaftlicher Artikel in Methods in Molecular Biology Methods Mol. Biol. 1567, 15-32 (2017)
Isolation of functional mitochondria from cultured cells and mouse tissues.
2017 Wissenschaftlicher Artikel in Diabetes Diabetes 66, 1247-1257 (2017)
Direct substrate delivery into mitochondrial-fission deficient pancreatic islets rescues insulin secretion.
2017 Editorial in Science Science 355, 1124-1125 (2017)
METABOLISM. Fat controls U. Circulating uridine acts as a hunger signal.
2017 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 13, 133-148 (2017)
Exercise-stimulated glucose uptake - regulation and implications for glycaemic control.
2017 Letter to the Editor in Diabetes Diabetes 66, e6-e6 (2017)
Response to comment on Ussar et al. Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor. Diabetes 2017;66:886-896.
2017 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 8:15143 (2017)
TNFα drives mitochondrial stress in POMC neurons in obesity.
2017 Review in Cell Cell 168, 758-774 (2017)
Gut-brain cross-talk in metabolic control.
2017 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 6, 440-446 (2017)
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice.
2017 Molecular Psychiatry Mol. Psychiatry 22, 321-322 (2017)
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index (vol 22, pg 192, 2017).
2017 Wissenschaftlicher Artikel in Nature medicine Nat. Med. 23, 623-630 (2017)
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis.
2017 Wissenschaftlicher Artikel in Journal of Thermal Biology J. Therm. Biol. 68, 83-88 (2017)
Phylogenetic analysis of the allometry of metabolic rate and mitochondrial basal proton leak.
2017 Review in Trends in Neurosciences Trends Neurosci. 40, 167-180 (2017)
Current understanding of the hypothalamic ghrelin pathways inducing appetite and adiposity.
2017 Wissenschaftlicher Artikel in Science Translational Medicine Sci. Transl. Med. 9:eaaf8848 (2017)
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.
2017 Wissenschaftlicher Artikel in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 19, 599-603 (2017)
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor.
2017 Review in Biochimie Biochimie 134, 77-85 (2017)
Targeted mitochondrial uncoupling beyond UCP1 - The fine line between death and metabolic health.
2017 Wissenschaftlicher Artikel in Molecular Psychiatry Mol. Psychiatry 22, 192-201 (2017)
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.
2016 Wissenschaftlicher Artikel in Biochimica et Biophysica Acta Biochim. Biophys. Acta 1863, 1054-1065 (2016)
Positive feedback amplifies the response of mitochondrial membrane potential to glucose concentration in clonal pancreatic beta cells.
2016 Letter to the Editor in Obstetrical & gynecological survey Obstet. Gynecol. Surv. 71, 719-720 (2016)
Epigenetic germline inheritance of diet-induced obesity and insulin resistance.
2016 Wissenschaftlicher Artikel in PLoS Pathogens PLoS Pathog. 12:e1005405 (2016)
A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog.
2016 Wissenschaftlicher Artikel in Journal of Clinical Investigation J. Clin. Invest. 126, 4430-4443 (2016)
Antibiotic effects on gut microbiota and metabolism are host dependent.
2016 Wissenschaftlicher Artikel in Deutsches Ärzteblatt Dtsch. Ärztebl. 113, 27-29 (2016)
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2016 Wissenschaftlicher Artikel in South African Journal of Botany S. Afr. J. Bot., DOI: 10.1016/j.sajb.2016.08.007 (2016)
A polyphenol-enriched fraction of Cyclopia intermedia decreases lipid content in 3T3-L1 adipocytes and reduces body weight gain of obese db/db mice.
2016 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 5, 1015-24 (2016)
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2016 Wissenschaftlicher Artikel in Drug research Drug Res. (Stuttg) 66, S.10 (2016)
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2016 Wissenschaftlicher Artikel in Journal of Psychosomatic Research J. Psychosomat. Res. 91, 9-11 (2016)
Effectiveness of a placebo intervention on visually induced nausea in women – A randomized controlled pilot study.
2016 Wissenschaftlicher Artikel in Molecular Neurodegeneration Mol. Neurodegener. 11:67 (2016)
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
2016 Wissenschaftlicher Artikel in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, E6659-E6668 (2016)
miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.
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Seasonal control of mammalian energy balance: Recent advances in the understanding of daily torpor and hibernation.
2016 Wissenschaftlicher Artikel in Immunity Immunity 45, 761-773 (2016)
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria.
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Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
2016 Wissenschaftlicher Artikel in Molecular Metabolism Mol. Metab. 5, 807-822 (2016)
α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors.
2016 Wissenschaftlicher Artikel in Journal of natural medicines J. Nat. Med. 22, 970-971 (2016)
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2016 Meeting abstract in Journal of Neurochemistry J. Neurochem. 138, 1, 422-422 (2016)
TREM2-deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
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Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic Impact for metabolic disease.
2016 Wissenschaftlicher Artikel in Diabetes Diabetes 66, 272-286:db160381 (2016)
Adipocyte glucocorticoid receptor deficiency attenuates aging and HFDinduced obesity, and impairs the feedingfasting transition.
2016 Wissenschaftlicher Artikel in Journal of Chromatography J. Chromatogr. B 1033-1034, 413-420 (2016)
Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography-mass spectrometry method.
Frankfurt am Main: Lang, Peter, 2016. 388 S.
Zivilisationskrankheiten – Für eine gesamtwissenschaftliche Prädiktion und Prävention. Molekulare, phänomenologische, systemische und gestalttheoretische Analyse von Altersdiabetes.
2016 Wissenschaftlicher Artikel in Journal of Experimental Medicine J. Exp. Med. 213, 2065-2080 (2016)
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.
2016 Review in Molecular Metabolism Mol. Metab. 5, 795-803 (2016)
Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome.
2016 Meeting abstract in Journal of Immunology J. Immunol. 196, 1 (2016)
The transcriptional regulator Bcl-3 impaires the function of regulatory T cells leading to the development of intestinal inflammation.
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A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
2016 Wissenschaftlicher Artikel in Glia Glia 64, 1962-1971 (2016)
The insulin-like growth factor I receptor regulates glucose transport by astrocytes.
2016 Wissenschaftlicher Artikel in Cell Cell 166, 867-880 (2016)
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Immunological characterization of intraocular lymphoid follicles in a spontaneous recurrent uveitis model.
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Absence of the autophagy adaptor SQSTM1/p62 causes childhood-onset neurodegeneration with ataxia, dystonia, and gaze palsy.
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3 screen ELISA for high-throughput detection of beta cell autoantibodies in capillary blood.
2016 Wissenschaftlicher Artikel in Frontiers in Endocrinology Front. Endocrin. 7:109 (2016)
Ring finger protein 11 inhibits melanocortin 3 and 4 receptor signaling.
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GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight.
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MTORC2 and AMPK differentially regulate muscle triglyceride content via perilipin 3.
2016 Editorial in Cell Metabolism Cell Metab. 24, 194-195 (2016)
Metabolic precision medicines: Curing POMC deficiency.
2016 Wissenschaftlicher Artikel in PLoS ONE PLoS ONE 11:e0159199 (2016)
Measurement of the absolute magnitude and time courses of mitochondrial membrane potential in primary and clonal pancreatic beta-cells.
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Ghrelin regulates glucose and glutamate transporters in hypothalamic astrocytes.
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Identification of proliferative and mature β-cells in the islets of Langerhans.
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Ghrelin modulates encoding-related brain function without enhancing memory formation in humans.
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TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
2016 Review in Cell Metabolism Cell Metab. 24, 51-62 (2016)
Unimolecular polypharmacy for treatment of diabetes and obesity.
2016 Wissenschaftlicher Artikel in Current Diabetes Reports Curr. Diab. Rep. 16:75 (2016)
Follicular helper T cells in autoimmunity.
2016 Sonstiges: Nachrichtenmeldung in Cell Metabolism Cell Metab. 23, 959-960 (2016)
Opposing effects of antidiabetic interventions on malignant growth and metastasis.
2016 Wissenschaftlicher Artikel in Arteriosclerosis, Thrombosis, and Vascular Biology Arterioscler. Thromb. Vasc. Biol. 36, 1534-1548 (2016)
Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.
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Unforeseen role for glucocorticoids in combinatorial anti-obesity pharmacology.
2016 Wissenschaftlicher Artikel in Diabetologia Diabetologia 59, 1973-1976 (2016)
Tetraspanin 7 autoantibodies in type 1 diabetes.
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Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: Design and initial results of the Fr1da study.
2016 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 6:24631 (2016)
Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism.
2016 Wissenschaftlicher Artikel in Science Signaling Sci. Signal. 9:ra43 (2016)
Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.
2016 Review in Current Opinion in Behavioral Sciences Curr. Opin. Behav. Sci. 9, 126-135 (2016)
Dietary triglycerides as signaling molecules that influence reward and motivation.
2016 Rezension in Molecular Metabolism Mol. Metab. 5, 253-254 (2016)
Insulin receptor trafficking steers insulin action.
2016 Review in Trends in Molecular Medicine Trends Mol. Med. 22, 359-376 (2016)
Reappraisal of GIP pharmacology for metabolic diseases.
2016 Wissenschaftlicher Artikel in Ecology and Evolution Ecol. Evol. 6, 2516-2535 (2016)
Diversification and coevolution of the ghrelin/growth hormone secretagogue receptor system in vertebrates.
2016 Review in Diabetologia Diabetologia 59, 920-927 (2016)
Renaissance of leptin for obesity therapy.
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Epigenetic germline inheritance of diet-induced obesity and insulin resistance.
2016 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 7:10782 (2016)
Hypothalamic leptin action is mediated by histone deacetylase 5.
2016 Editorial in Diabetes Diabetes 65, 551-553 (2016)
Hypothalamic injury: Fish oil to the rescue!
2016 Wissenschaftlicher Artikel in PLoS ONE PLoS ONE 11:e0149477 (2016)
Pitchfork and Gprasp2 target smoothened to the primary cilium for Hedgehog pathway activation.
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Assays for insulin and insulin-like metabolic activity based on hepatocytes, myocytes and diaphragms.
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Measurement of insulin and other glucose-regulating peptide hormones.
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Monitoring of diabetic late complication.
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Personalized diagnosis and therapy.
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Assays for insulin and Insulin-like regulation of energy metabolism.
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Insulin analogs: Assessment of insulin mitogenicity and IGF-I activity.
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Insulin target tissues and cells.
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Assays for insulin and insulin-like activity based on adipocytes.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2623-2656
Measurement of blood glucose-lowering and antidiabetic activity.
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Assays for insulin and insulin-like regulation of gene and protein expression.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3059-3070
Measurement of glucose absorption.
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Methods to induce experimental Diabetes Mellitus.
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Genetically diabetic animals.
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Assays for insulin and insulin-like signal transduction based on adipocytes, hepatocytes and myocytes.
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Assays for the expression and release of insulin and glucose-regulating peptide hormones from pancreatic β-cell.
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A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog.
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Incretin-like effects of small molecule trace amine-associated receptor 1 agonists.
2016 Editorial in Cell Cell 164, 341-342 (2016)
Epigenetic ON/OFF switches for obesity.
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Longitudinal frequencies of blood leukocyte sub-populations differ between NOD and NOR mice, but do not predict diabetes in NOD mice.
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Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.
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The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.
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Deletion of monoglyceride lpase in astrocytes attenuates lipopolysaccharide-induced neuroinflammation.
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eggNOG 4.5: A hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences.
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